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Anatomy and Pathology/Oncology

Analysis of Ocular Hypopigmentation in Rab38 cht/cht Mice Free
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Brian P. Brooks; Denise M. Larson; Chi-Chao Chan; Sten Kjellstrom; Richard S. Smith; Mary A. Crawford; Lynn Lamoreux; Marjan Huizing; Richard Hess; Xiaodong Jiao; J. Fielding Hejtmancik; Arvydas Maminishkis; Simon W. M. John; Ronald Bush; William J. Pavan
Tags: hypopigmentation disorder, mice, proteins, eye, melanosomes
Investigative Ophthalmology & Visual Science September 2007, Vol.48, 3905-3913. doi:https://doi.org/10.1167/iovs.06-1464
Effects of Foveal Ablation on Emmetropization and Form-Deprivation Myopia Free
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Earl L. Smith, III; Ramkumar Ramamirtham; Ying Qiao-Grider; Li-Fang Hung; Juan Huang; Chea-su Kee; David Coats; Evelyn Paysse
Tags: ablation, cercopithecidae, eye, myopia, refractive errors
Investigative Ophthalmology & Visual Science September 2007, Vol.48, 3914-3922. doi:https://doi.org/10.1167/iovs.06-1264
Localization of D-β-Aspartic Acid–Containing Proteins in Human Eyes Free
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Yuichi Kaji; Tetsuro Oshika; Yutaka Takazawa; Masashi Fukayama; Takumi Takata; Noriko Fujii
Tags: antibodies, eye, lens, crystalline, peptides, proteins
Investigative Ophthalmology & Visual Science September 2007, Vol.48, 3923-3927. doi:https://doi.org/10.1167/iovs.06-1284

Biochemistry and Molecular Biology

Expression of JAM-A in the Human Corneal Endothelium and Retinal Pigment Epithelium: Localization and Evidence for Role in Barrier Function Free
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Kenneth J. Mandell; Lennart Berglin; Eric A. Severson; Henry F. Edelhauser; Charles A. Parkos
Tags: antibodies, corneal endothelium, fluorescent antibody technique, retinal pigment epithelium, microscopy, confocal
Investigative Ophthalmology & Visual Science September 2007, Vol.48, 3928-3936. doi:https://doi.org/10.1167/iovs.06-1536
Genetic Heterogeneity in Microcornea-Cataract: Five Novel Mutations in CRYAA, CRYGD, and GJA8 Free
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Lars Hansen; Wenliang Yao; Hans Eiberg; Klaus Wilbrandt Kjaer; Kirsten Baggesen; J. Fielding Hejtmancik; Thomas Rosenberg
Tags: cataract, genetic heterogeneity, microcornea, mutation, phenotype
Investigative Ophthalmology & Visual Science September 2007, Vol.48, 3937-3944. doi:https://doi.org/10.1167/iovs.07-0013
Detection of Surfactant Proteins A and D in Human Tear Fluid and the Human Lacrimal System Free
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Lars Bräuer; Christian Kindler; Kristin Jäger; Saadettin Sel; Bernhard Nölle; Uwe Pleyer; Matthias Ochs; Friedrich P. Paulsen
Tags: body tissue, cornea, lacrimal apparatus, proteins, pulmonary surfactants
Investigative Ophthalmology & Visual Science September 2007, Vol.48, 3945-3953. doi:https://doi.org/10.1167/iovs.07-0201
AAV-Mediated Expression Targeting of Rod and Cone Photoreceptors with a Human Rhodopsin Kinase Promoter Free
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Shahrokh C. Khani; Basil S. Pawlyk; Oleg V. Bulgakov; Eileen Kasperek; Joyce E. Young; Michael Adamian; Xun Sun; Alexander J. Smith; Robin R. Ali; Tiansen Li
Tags: opsin, phosphotransferases, retinal cone, rhodopsin, rod photoreceptors
Investigative Ophthalmology & Visual Science September 2007, Vol.48, 3954-3961. doi:https://doi.org/10.1167/iovs.07-0257
Prediction and Verification of miRNA Expression in Human and Rat Retinas Free
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Amit Arora; Gareth J. McKay; David A. C. Simpson
Tags: micrornas, retina
Investigative Ophthalmology & Visual Science September 2007, Vol.48, 3962-3967. doi:https://doi.org/10.1167/iovs.06-1221
Ferritin H- and L-Chains in Fiber Cell Canine and Human Lenses of Different Ages Free
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Malgorzata Goralska; Lloyd N. Fleisher; M. Christine McGahan
Tags: dog, domestic, ferritin, lens (device), lens, crystalline
Investigative Ophthalmology & Visual Science September 2007, Vol.48, 3968-3975. doi:https://doi.org/10.1167/iovs.07-0130
Modified Saponification and HPLC Methods for Analyzing Carotenoids from the Retina of Quail: Implications for Its Use as a Nonprimate Model Species Free
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Matthew B. Toomey; Kevin J. McGraw
Tags: carotenoids, high pressure liquid chromatography procedure, quail, retina
Investigative Ophthalmology & Visual Science September 2007, Vol.48, 3976-3982. doi:https://doi.org/10.1167/iovs.07-0208

Clinical and Epidemiologic Research

Progression of Diabetic Macular Edema: Correlation with Blood–Retinal Barrier Permeability, Retinal Thickness, and Retinal Vessel Diameter Free
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Birgit Sander; Dorte Nellemann Thornit; Lotte Colmorn; Charlotte Strøm; Aniz Girach; Larry D. Hubbard; Henrik Lund-Andersen; Michael Larsen
Tags: blood-retinal barrier, diabetic macular edema, diameter, eye, light coagulation
Investigative Ophthalmology & Visual Science September 2007, Vol.48, 3983-3987. doi:https://doi.org/10.1167/iovs.06-1102
Estimating the Amount of Mental Effort Required for Independent Mobility: Persons with Glaucoma Free
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Duane R. Geruschat; Kathleen A. Turano
Tags: glaucoma, mobility
Investigative Ophthalmology & Visual Science September 2007, Vol.48, 3988-3994. doi:https://doi.org/10.1167/iovs.06-1193
The Impact of Optical Factors on Resolution Acuity in Children with Down Syndrome Free
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Julie-Anne Little; J. Margaret Woodhouse; Jan S. Lauritzen; Kathryn J. Saunders
Tags: child, down syndrome, optics, refractive errors
Investigative Ophthalmology & Visual Science September 2007, Vol.48, 3995-4001. doi:https://doi.org/10.1167/iovs.06-1387
Heritability and Familial Aggregation of Refractive Error in the Old Order Amish Free
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Jon A. Peet; Mary-Frances Cotch; Robert Wojciechowski; Joan E. Bailey-Wilson; Dwight Stambolian
Tags: refractive errors, myopia, hyperopia
Investigative Ophthalmology & Visual Science September 2007, Vol.48, 4002-4006. doi:https://doi.org/10.1167/iovs.06-1388
Exposure to Chlamydia pneumoniae Infection and Age-Related Macular Degeneration: The Blue Mountains Eye Study Free
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Luba Robman; Olaimatu S. Mahdi; Jie Jin Wang; George Burlutsky; Paul Mitchell; Gerald Byrne; Robyn Guymer; Hugh Taylor
Tags: age-related macular degeneration, chlamydia pneumoniae infections, eye, smoking, antibody titer
Investigative Ophthalmology & Visual Science September 2007, Vol.48, 4007-4011. doi:https://doi.org/10.1167/iovs.06-1434
A Population-Based Epidemiological and Genetic Study of X-Linked Retinitis Pigmentosa Free
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Holger Prokisch; Monika Hartig; Rosa Hellinger; Thomas Meitinger; Thomas Rosenberg
Tags: family, genes, genetic research, mutation, retinitis pigmentosa
Investigative Ophthalmology & Visual Science September 2007, Vol.48, 4012-4018. doi:https://doi.org/10.1167/iovs.07-0071
Retinopathy in Persons without Diabetes: The Los Angeles Latino Eye Study Free
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Jennifer R. Chao; Mei-Ying Lai; Stanley P. Azen; Ronald Klein; Rohit Varma; the Los Angeles Latino Eye Study Group
Tags: diabetes mellitus, eye, retinal diseases, hispanics or latinos, risk factors
Investigative Ophthalmology & Visual Science September 2007, Vol.48, 4019-4025. doi:https://doi.org/10.1167/iovs.07-0206

Cornea

Exposure to a Controlled Adverse Environment Impairs the Ocular Surface of Subjects with Minimally Symptomatic Dry Eye Free
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Maria J. González-García; Arancha González-Sáiz; Beatriz de la Fuente; Antonio Morilla-Grasa; Agustin Mayo-Iscar; Julio San-José; Jesus Feijó; Michael E. Stern; Margarita Calonge
Tags: capillary leak syndrome, cyclophosphamide/doxorubicin/etoposide, de lange syndrome, dry eye syndromes, phenolsulfonphthalein
Investigative Ophthalmology & Visual Science September 2007, Vol.48, 4026-4032. doi:https://doi.org/10.1167/iovs.06-0817
Impulse Activity in Corneal Sensory Nerve Fibers after Photorefractive Keratectomy Free
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Juana Gallar; M. Carmen Acosta; A. Ramón Gutiérrez; Carlos Belmonte
Tags: cornea, impulse, sensory nerves, wounds and injuries, fanconi syndrome
Investigative Ophthalmology & Visual Science September 2007, Vol.48, 4033-4037. doi:https://doi.org/10.1167/iovs.07-0012
Coated Microneedles for Drug Delivery to the Eye Free
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Jason Jiang; Harvinder S. Gill; Deepta Ghate; Bernard E. McCarey; Samir R. Patel; Henry F. Edelhauser; Mark R. Prausnitz
Tags: drug delivery systems, eye, fluorescein, pilocarpine, cornea
Investigative Ophthalmology & Visual Science September 2007, Vol.48, 4038-4043. doi:https://doi.org/10.1167/iovs.07-0066
Effect of Allergic Conjunctival Inflammation on the Allogeneic Response to Donor Cornea Free
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Thomas H. Flynn; Masaharu Ohbayashi; Yoshifumi Ikeda; Santa J. Ono; Daniel F. Larkin
Tags: allergic conjunctivitis, allografting, conjunctivitis, cornea, donors
Investigative Ophthalmology & Visual Science September 2007, Vol.48, 4044-4049. doi:https://doi.org/10.1167/iovs.06-0973
Morphologic Characterization of Organized Extracellular Matrix Deposition by Ascorbic Acid–Stimulated Human Corneal Fibroblasts Free
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Xiaoqing Guo; Audrey E. K. Hutcheon; Suzanna A. Melotti; James D. Zieske; Vickery Trinkaus-Randall; Jeffrey W. Ruberti
Tags: ascorbic acid, collagen, cornea, extracellular matrix, fibril
Investigative Ophthalmology & Visual Science September 2007, Vol.48, 4050-4060. doi:https://doi.org/10.1167/iovs.06-1216
Postnatal Corneal Transparency, Keratocyte Cell Cycle Exit and Expression of ALDH1A1 Free
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James V. Jester; Young G. Lee; Jiying Huang; Jennifer Houston; Brook Adams; H. Dwight Cavanagh; W. Matthew Petroll
Tags: cell cycle, cornea, crystallins, keratocytes, proteins
Investigative Ophthalmology & Visual Science September 2007, Vol.48, 4061-4069. doi:https://doi.org/10.1167/iovs.07-0431

Eye Movements, Strabismus, Amblyopia and Neuro-ophthalmology

Validation Study of VEP Vernier Acuity in Normal-Vision and Amblyopic Adults Free
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Chuan Hou; William V. Good; Anthony M. Norcia
Tags: amblyopia, emmetropia, evoked potentials, visual, psychophysics, validation studies
Investigative Ophthalmology & Visual Science September 2007, Vol.48, 4070-4078. doi:https://doi.org/10.1167/iovs.06-1368
Reduction of Inner Retinal Thickness in Patients with Autosomal Dominant Optic Atrophy Associated with OPA1 Mutations Free
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Yasuki Ito; Makoto Nakamura; Tomomi Yamakoshi; Jian Lin; Hiroshi Yatsuya; Hiroko Terasaki
Tags: mutation, optic atrophy, autosomal dominant, retinal nerve fiber layer, retina, visual acuity
Investigative Ophthalmology & Visual Science September 2007, Vol.48, 4079-4086. doi:https://doi.org/10.1167/iovs.07-0024
Optic Disc Evaluation by Optical Coherence Tomography in Nonarteritic Anterior Ischemic Optic Neuropathy Free
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Inés Contreras; Gema Rebolleda; Susana Noval; Francisco J. Muñoz-Negrete
Tags: nonarteritic anterior ischemic optic neuropathy, optic disk, optical coherence tomography, eye
Investigative Ophthalmology & Visual Science September 2007, Vol.48, 4087-4092. doi:https://doi.org/10.1167/iovs.07-0171
Acuity Development in Infantile Nystagmus Free
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Avery H. Weiss; John P. Kelly
Tags: albinism, aniridia, pathologic nystagmus
Investigative Ophthalmology & Visual Science September 2007, Vol.48, 4093-4099. doi:https://doi.org/10.1167/iovs.06-1165

Glaucoma

The British Infantile and Childhood Glaucoma (BIG) Eye Study Free
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Maria Papadopoulos; Noriko Cable; Jugnoo Rahi; Peng Tee Khaw; the BIG Eye Study Investigators
Tags: child, eye, glaucoma, glaucoma, congenital, glaucoma, primary
Investigative Ophthalmology & Visual Science September 2007, Vol.48, 4100-4106. doi:https://doi.org/10.1167/iovs.06-1350
Bimatoprost, Prostamide Activity, and Conventional Drainage Free
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Zhou Wan; David F. Woodward; Clive L. Cornell; Hans G. Fliri; José L. Martos; Simon N. Pettit; Jenny W. Wang; Alexander B. Kharlamb; Larry A. Wheeler; Michael E. Garst; Kari J. Landsverk; Craig S. Struble; W. Daniel Stamer
Tags: bimatoprost, drainage procedure, discharge, body substance, perfusion
Investigative Ophthalmology & Visual Science September 2007, Vol.48, 4107-4115. doi:https://doi.org/10.1167/iovs.07-0080
Dynamic Analysis of Dark–Light Changes of the Anterior Chamber Angle with Anterior Segment OCT Free
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Christopher Kai-shun Leung; Carol Yim Lui Cheung; Haitao Li; Syril Dorairaj; Cedric Ka Fai Yiu; Amy Lee Wong; Jeffrey Liebmann; Robert Ritch; Robert Weinreb; Dennis Shun Chiu Lam
Tags: anterior chamber of eye, gonioscopy
Investigative Ophthalmology & Visual Science September 2007, Vol.48, 4116-4122. doi:https://doi.org/10.1167/iovs.07-0010
In Vitro Studies of Antiglaucomatous Prostaglandin Analogues: Travoprost with and without Benzalkonium Chloride and Preserved Latanoprost Free
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Christophe Baudouin; Luisa Riancho; Jean-Michel Warnet; Françoise Brignole
Tags: annexin a5, apoptosis, benzalkonium chloride, latanoprost, necrosis
Investigative Ophthalmology & Visual Science September 2007, Vol.48, 4123-4128. doi:https://doi.org/10.1167/iovs.07-0266
Hsp27 Phosphorylation in Experimental Glaucoma Free
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Wei Huang; John B. Fileta; Theodoros Filippopoulos; Arjun Ray; Adam Dobberfuhl; Cynthia L. Grosskreutz
Tags: glaucoma, phosphorylation, raised intraocular pressure, intraocular pressure, retina
Investigative Ophthalmology & Visual Science September 2007, Vol.48, 4129-4135. doi:https://doi.org/10.1167/iovs.06-0606
Genome-Wide Scan of Exfoliation Syndrome Free
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Susanna Lemmelä; Eva Forsman; Pertti Sistonen; Aldur Eriksson; Henrik Forsius; Irma Järvelä
Tags: exfoliation syndrome, genome, lod score, open-angle glaucoma, family
Investigative Ophthalmology & Visual Science September 2007, Vol.48, 4136-4142. doi:https://doi.org/10.1167/iovs.06-1092
Effect of 15-Keto Latanoprost on Intraocular Pressure and Aqueous Humor Dynamics in Monkey Eyes Free
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Rong-Fang Wang; Donna J. Gagliuso; Thomas W. Mittag; Steven M. Podos
Tags: aqueous humor, cercopithecidae, eye, intraocular pressure, latanoprost
Investigative Ophthalmology & Visual Science September 2007, Vol.48, 4143-4147. doi:https://doi.org/10.1167/iovs.07-0035

Immunology and Microbiology

Expression of Indoleamine 2,3-Dioxygenase in Human Corneal Cells as a Local Immunosuppressive Factor Free
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Yang-Hwan Ryu; Jae-Chan Kim
Tags: cornea, immunosuppressive agents, tryptophan oxygenase, culture media, conditioned, t-lymphocytes
Investigative Ophthalmology & Visual Science September 2007, Vol.48, 4148-4152. doi:https://doi.org/10.1167/iovs.05-1336
Characterization of IL-17+ Interphotoreceptor Retinoid-Binding Protein-Specific T Cells in Experimental Autoimmune Uveitis Free
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Yong Peng; Gencheng Han; Hui Shao; Yali Wang; Henry J. Kaplan; Deming Sun
Tags: autoimmune diseases, interleukin-17, t-lymphocytes, uveitis, proteins
Investigative Ophthalmology & Visual Science September 2007, Vol.48, 4153-4161. doi:https://doi.org/10.1167/iovs.07-0251
Effects of CXCR3 Signaling on Development of Fatal Encephalitis and Corneal and Periocular Skin Disease in HSV-Infected Mice Are Mouse-Strain Dependent Free
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Patric Lundberg; Harry Openshaw; Mingwu Wang; Hui-Jung Yang; Edouard Cantin
Tags: cornea, encephalitis, mice, signal transduction, skin disorders
Investigative Ophthalmology & Visual Science September 2007, Vol.48, 4162-4170. doi:https://doi.org/10.1167/iovs.07-0261
Efficacy of Topical Immunoglobulins against Experimental Adenoviral Ocular Infection Free
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Edward C. Nwanegbo; Eric G. Romanowski; Y. Jerold Gordon; Andrea Gambotto
Tags: adenoviruses, antiviral agents, eye infections, immunoglobulins
Investigative Ophthalmology & Visual Science September 2007, Vol.48, 4171-4176. doi:https://doi.org/10.1167/iovs.07-0491

Lens

Purinergic Receptor–Mediated Regulation of Lens Connexin43 Free
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Monica M. Lurtz; Charles F. Louis
Tags: connexin 43, dyes, purinoceptor, hela cells, gap junction protein
Investigative Ophthalmology & Visual Science September 2007, Vol.48, 4177-4186. doi:https://doi.org/10.1167/iovs.06-0496
p53 Expression and Apoptosis in the Lens after Ultraviolet Radiation Exposure Free
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Marcelo Ayala; Hilja Strid; Ulrika Jacobsson; Per G. Söderberg
Tags: apoptosis, caspase-3, lens (device), lens, crystalline, protein p53
Investigative Ophthalmology & Visual Science September 2007, Vol.48, 4187-4191. doi:https://doi.org/10.1167/iovs.06-0660
MMP and TIMP Expression in Quiescent, Dividing, and Differentiating Human Lens Cells Free
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Lisa M. Hodgkinson; George Duncan; Lixin Wang; Caroline J. Pennington; Dylan R. Edwards; I. Michael Wormstone
Tags: lens (device), lens, crystalline, tissue inhibitor of metalloproteinases, proteins, gene expression
Investigative Ophthalmology & Visual Science September 2007, Vol.48, 4192-4199. doi:https://doi.org/10.1167/iovs.06-1371
Degradation of C-terminal Truncated αA-crystallins by the Ubiquitin–Proteasome Pathway Free
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Xinyu Zhang; Edward J. Dudek; Bingfen Liu; Linlin Ding; Alexandre F. Fernandes; Jack J. Liang; Joseph Horwitz; Allen Taylor; Fu Shang
Tags: catabolism, crystallins
Investigative Ophthalmology & Visual Science September 2007, Vol.48, 4200-4208. doi:https://doi.org/10.1167/iovs.07-0196
Anterior Capsular Plaque in Congenital Cataract: Occurrence, Morphology, Immunofluorescence, and Ultrastructure Free
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Kaid Johar; Abhay R. Vasavada; Kouko Tatsumi; Sheena Dholakia; Bharti Nihalani; Sarraju S. Lakshmana Rao
Tags: congenital cataract, fluorescent antibody technique, language morphology, morphology, cataract
Investigative Ophthalmology & Visual Science September 2007, Vol.48, 4209-4214. doi:https://doi.org/10.1167/iovs.07-0312

Physiology and Pharmacology

Role of Nitric Oxide in Choroidal Blood Flow Regulation during Light/Dark Transitions Free
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Karl-Heinz Huemer; Gerhard Garhofer; Tina Aggermann; Julia Kolodjaschna; Leopold Schmetterer; Gabriele Fuchsjäger-Mayrl
Tags: nitric oxide, regulation, vascular flow, omega-n-methylarginine, phenylephrine
Investigative Ophthalmology & Visual Science September 2007, Vol.48, 4215-4219. doi:https://doi.org/10.1167/iovs.07-0176
Effects of Topical Clonidine versus Brimonidine on Choroidal Blood Flow and Intraocular Pressure during Squatting Free
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Günther Weigert; Hemma Resch; Gerhard Garhofer; Gabriele Fuchsjäger-Mayrl; Leopold Schmetterer
Tags: brimonidine, clonidine, intraocular pressure, squatting ability, vascular flow
Investigative Ophthalmology & Visual Science September 2007, Vol.48, 4220-4225. doi:https://doi.org/10.1167/iovs.07-0178

Retina

The Prime Role of HDL to Transport Lutein into the Retina: Evidence from HDL-Deficient WHAM Chicks Having a Mutant ABCA1 Transporter Free
PDF
William E. Connor; P. Barton Duell; Ron Kean; Yingming Wang
Tags: high density lipoproteins, lutein, retina, plasma, membrane transport proteins
Investigative Ophthalmology & Visual Science September 2007, Vol.48, 4226-4231. doi:https://doi.org/10.1167/iovs.06-1275
Resveratrol, a Component of Red Wine, Elicits Dilation of Isolated Porcine Retinal Arterioles: Role of Nitric Oxide and Potassium Channels Free
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Taiji Nagaoka; Travis W. Hein; Akitoshi Yoshida; Lih Kuo
Tags: arteriole, dilatation, pathologic, nitric oxide, potassium channel, resveratrol
Investigative Ophthalmology & Visual Science September 2007, Vol.48, 4232-4239. doi:https://doi.org/10.1167/iovs.07-0094
Pathological and Electrophysiological Features of a Canine Cone–Rod Dystrophy in the Miniature Longhaired Dachshund Free
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Clare Turney; N. H. Victor Chong; Robert A. Alexander; Chris R. Hogg; Lorraine Fleming; Deborah Flack; Keith C. Barnett; Alan C. Bird; Graham E. Holder; Philip J. Luthert
Tags: dog, domestic, electroretinography, erg protein, human, progressive cone-rod dystrophy, retinal cone
Investigative Ophthalmology & Visual Science September 2007, Vol.48, 4240-4249. doi:https://doi.org/10.1167/iovs.04-0737
Pseudoxanthoma Elasticum with Generalized Retinal Dysfunction, a Common Finding? Free
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Isabelle Audo; Olivier M. Vanakker; Alaric Smith; Bart P. Leroy; Anthony G. Robson; Sharon A. Jenkins; Paul J. Coucke; Alan C. Bird; Anne De Paepe; Graham E. Holder; Andrew R. Webster
Tags: pathophysiology, pseudoxanthoma elasticum, electroretinography
Investigative Ophthalmology & Visual Science September 2007, Vol.48, 4250-4256. doi:https://doi.org/10.1167/iovs.05-1604
Chemotactic Effect of Ciliary Neurotrophic Factor on Macrophages in Retinal Ganglion Cell Survival and Axonal Regeneration Free
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Ling-Ping Cen; Jian-Min Luo; Cheng-Wu Zhang; You-Ming Fan; Yue Song; Kwok-Fai So; Nico van Rooijen; Chi Pui Pang; Dennis S. C. Lam; Qi Cui
Tags: ciliary neurotrophic factor, macrophages, eye, retinal ganglion cells
Investigative Ophthalmology & Visual Science September 2007, Vol.48, 4257-4266. doi:https://doi.org/10.1167/iovs.06-0791
Effect of VEGF-A on Expression of Profibrotic Growth Factor and Extracellular Matrix Genes in the Retina Free
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Esther J. Kuiper; John M. Hughes; Rob J. Van Geest; Ilse M. C. Vogels; Roel Goldschmeding; Cornelis J. F. Van Noorden; Reinier O. Schlingemann; Ingeborg Klaassen
Tags: genes, retina, rna, messenger, vascular endothelial growth factor a, growth factor
Investigative Ophthalmology & Visual Science September 2007, Vol.48, 4267-4276. doi:https://doi.org/10.1167/iovs.06-0804
Haplotypes Spanning the Complement Factor H Gene Are Protective against Age-Related Macular Degeneration Free
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Kylee L. Spencer; Michael A. Hauser; Lana M. Olson; Nathalie Schnetz-Boutaud; William K. Scott; Silke Schmidt; Paul Gallins; Anita Agarwal; Eric A. Postel; Margaret A. Pericak-Vance; Jonathan L. Haines
Tags: age-related macular degeneration, complement factor h, genes, haplotypes, smoking
Investigative Ophthalmology & Visual Science September 2007, Vol.48, 4277-4283. doi:https://doi.org/10.1167/iovs.06-1427
Clinical and Molecular Genetics of Leber's Congenital Amaurosis: A Multicenter Study of Italian Patients Free
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Francesca Simonelli; Carmela Ziviello; Francesco Testa; Settimio Rossi; Elisa Fazzi; Paolo Emilio Bianchi; Maurizio Fossarello; Sabrina Signorini; Chiara Bertone; Silvana Galantuomo; Francesco Brancati; Enza Maria Valente; Alfredo Ciccodicola; Ernesto Rinaldi; Alberto Auricchio; Sandro Banfi
Tags: genes, genetics, molecular, italian, leber's amaurosis, multicenter studies
Investigative Ophthalmology & Visual Science September 2007, Vol.48, 4284-4290. doi:https://doi.org/10.1167/iovs.07-0068
The Role of Gremlin, a BMP Antagonist, and Epithelial-to-Mesenchymal Transition in Proliferative Vitreoretinopathy Free
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Helena Lee; Sarah J. O'Meara; Colm O'Brien; Rosemary Kane
Tags: antagonists, epithelial to mesenchymal transition, vitreoretinopathy, proliferative, polymerase chain reaction, vimentin
Investigative Ophthalmology & Visual Science September 2007, Vol.48, 4291-4299. doi:https://doi.org/10.1167/iovs.07-0086
Reproducibility of Quantitative Optical Coherence Tomography Subanalysis in Neovascular Age-Related Macular Degeneration Free
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Sandra Joeres; Jerry W. Tsong; Paul G. Updike; Allyson T. Collins; Laurie Dustin; Alexander C. Walsh; Peggy W. Romano; SriniVas R. Sadda
Tags: body tissue, exudative age-related macular degeneration, eye, optical coherence tomography, retina
Investigative Ophthalmology & Visual Science September 2007, Vol.48, 4300-4307. doi:https://doi.org/10.1167/iovs.07-0179
Homozygosity for a Novel ABCA4 Founder Splicing Mutation Is Associated with Progressive and Severe Stargardt-like Disease Free
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Anat Beit-Ya'acov; Liliana Mizrahi-Meissonnier; Alexey Obolensky; Carmit Landau; Anat Blumenfeld; Ada Rosenmann; Eyal Banin; Dror Sharon
Tags: homozygote, mutation, rna splicing, haplotypes, stargardt's disease
Investigative Ophthalmology & Visual Science September 2007, Vol.48, 4308-4314. doi:https://doi.org/10.1167/iovs.07-0244
The Role of VEGF and VEGFR2/Flk1 in Proliferation of Retinal Progenitor Cells in Murine Retinal Degeneration Free
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Koji M. Nishiguchi; Makoto Nakamura; Hiroki Kaneko; Shu Kachi; Hiroko Terasaki
Tags: retinal degeneration, stem cells, vascular endothelial growth factor a, bromodeoxyuridine, mice
Investigative Ophthalmology & Visual Science September 2007, Vol.48, 4315-4320. doi:https://doi.org/10.1167/iovs.07-0354

Retinal Cell Biology

Endogenous Bone Marrow–Derived Cells Express Retinal Pigment Epithelium Cell Markers and Migrate to Focal Areas of RPE Damage Free
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Yang Li; Pelin Atmaca-Sonmez; Carrie L. Schanie; Suzanne T. Ildstad; Henry J. Kaplan; Volker Enzmann
Tags: bone marrow, coculture techniques, granulocyte colony-stimulating factor, mice, proto-oncogene protein c-kit
Investigative Ophthalmology & Visual Science September 2007, Vol.48, 4321-4327. doi:https://doi.org/10.1167/iovs.06-1015
Eicosapentaenoic Acid Is Anti-Inflammatory in Preventing Choroidal Neovascularization in Mice Free
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Takashi Koto; Norihiro Nagai; Hiroshi Mochimaru; Toshihide Kurihara; Kanako Izumi-Nagai; Shingo Satofuka; Hajime Shinoda; Kousuke Noda; Yoko Ozawa; Makoto Inoue; Kazuo Tsubota; Yuichi Oike; Susumu Ishida
Tags: anti-inflammatory agents, choroidal neovascularization, mice, eicosapentaenoic acid, peroxisome proliferator-activated receptors
Investigative Ophthalmology & Visual Science September 2007, Vol.48, 4328-4334. doi:https://doi.org/10.1167/iovs.06-1148
In Vivo Immunostaining Demonstrates Macrophages Associate with Growing and Regressing Vessels Free
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Jikui Shen; Bing Xie; Aling Dong; Mara Swaim; Sean F. Hackett; Peter A. Campochiaro
Tags: antibodies, cd31 antigens, immunohistochemistry, ischemia, macrophages
Investigative Ophthalmology & Visual Science September 2007, Vol.48, 4335-4341. doi:https://doi.org/10.1167/iovs.07-0113
Suppression of Diabetes-Induced Retinal Inflammation by Blocking the Angiotensin II Type 1 Receptor or Its Downstream Nuclear Factor-κB Pathway Free
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Norihiro Nagai; Kanako Izumi-Nagai; Yuichi Oike; Takashi Koto; Shingo Satofuka; Yoko Ozawa; Kenji Yamashiro; Makoto Inoue; Kazuo Tsubota; Kazuo Umezawa; Susumu Ishida
Tags: diabetes mellitus, diabetes mellitus, type 2, inflammation, intercellular adhesion molecule 1, receptor, angiotensin, type 1
Investigative Ophthalmology & Visual Science September 2007, Vol.48, 4342-4350. doi:https://doi.org/10.1167/iovs.06-1473
Rod Photoreceptor Function Predicts Blood Vessel Abnormality in Retinopathy of Prematurity Free
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James D. Akula; Ronald M. Hansen; M. Elena Martinez-Perez; Anne B. Fulton
Tags: electroretinography, rats, retinopathy of prematurity, rod photoreceptors, oxygen
Investigative Ophthalmology & Visual Science September 2007, Vol.48, 4351-4359. doi:https://doi.org/10.1167/iovs.07-0204
Positive Feedback Regulation between MMP-9 and VEGF in Human RPE Cells Free
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Margrit Hollborn; Christina Stathopoulos; Anja Steffen; Peter Wiedemann; Leon Kohen; Andreas Bringmann
Tags: gelatinase b, regulation, retinal pigment cell, vascular endothelial growth factor a, gelatinase a
Investigative Ophthalmology & Visual Science September 2007, Vol.48, 4360-4367. doi:https://doi.org/10.1167/iovs.06-1234

Visual Psychophysics and Physiological Optics

The Influence of Manual Dexterity on Reading Speed with a Hand-held Magnifier Free
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Chris Dickinson; Maggie Shim
Tags: hand-held magnifiers, jebsen-taylor hand function test, reading (activity), reading speed, finger-to-nose test
Investigative Ophthalmology & Visual Science September 2007, Vol.48, 4368-4374. doi:https://doi.org/10.1167/iovs.07-0001
Dynamics of Accommodative Facility in Myopes Free
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Hema Radhakrishnan; Peter M. Allen; W. Neil Charman
Tags: reaction time, visual accommodation, lens (device), lens, crystalline
Investigative Ophthalmology & Visual Science September 2007, Vol.48, 4375-4382. doi:https://doi.org/10.1167/iovs.07-0269
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