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Anatomy and Pathology/Oncology

AMD-like Lesions in the Rat Retina: A Latent Consequence of Perinatal Hemorrhage Free
PDF
David V. Pow; Claudia M. Diaz
Tags: hemorrhage, retina, macrophages, perinatal period, hemosiderin
Investigative Ophthalmology & Visual Science July 2008, Vol.49, 2790-2798. doi:https://doi.org/10.1167/iovs.08-1757
Targeting Hypoxia, a Novel Treatment for Advanced Retinoblastoma Free
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Hinda Boutrid; Maria-Elena Jockovich; Timothy G. Murray; Yolanda Piña; William J. Feuer; Theodore J. Lampidis; Colleen M. Cebulla
Tags: hypoxia, neoplasms, retinoblastoma
Investigative Ophthalmology & Visual Science July 2008, Vol.49, 2799-2805. doi:https://doi.org/10.1167/iovs.08-1751
Matrix Metalloproteinase-2 Is Expressed in Melanoma-Associated Spongiform Scleropathy Free
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Ghassan Ayish Alyahya; Miriam Kolko; Jan Ulrik Prause; Boye Schnack Nielsen; Jinmei Wang; Steffen Heegaard
Tags: gelatinase a, melanoma, sclera, neoplasms, fibroblasts
Investigative Ophthalmology & Visual Science July 2008, Vol.49, 2806-2811. doi:https://doi.org/10.1167/iovs.07-1436
Abnormal Vessel Formation in the Choroid of Mice Lacking Tissue Inhibitor of Metalloprotease-3 Free
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Andreas Janssen; Julia Hoellenriegel; Marton Fogarasi; Heinrich Schrewe; Mathias Seeliger; Ernst Tamm; Andreas Ohlmann; Christian Albrecht May; Bernhard H. F. Weber; Heidi Stöhr
Tags: metalloproteases, mice, choroid, body tissue
Investigative Ophthalmology & Visual Science July 2008, Vol.49, 2812-2822. doi:https://doi.org/10.1167/iovs.07-1444
Size Overlap between Benign Melanocytic Choroidal Nevi and Choroidal Malignant Melanomas Free
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James J. Augsburger; Zélia M. Corrêa; Nikolaos Trichopoulos; Adeel Shaikh
Tags: malignant melanoma of choroid, nevus, neoplasms, diameter, frequency distribution
Investigative Ophthalmology & Visual Science July 2008, Vol.49, 2823-2828. doi:https://doi.org/10.1167/iovs.07-1603

Biochemistry and Molecular Biology

Proteomic Analysis of Climatic Keratopathy Droplets Free
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Michelle Menegay; DeMia Lee; Khalid F. Tabbara; Thamara A. Cafaro; Julio A. Urrets-Zavalía; Horacio M. Serra; Sanjoy K. Bhattacharya
Tags: cornea, labrador keratopathy, proteins, dose fractionation
Investigative Ophthalmology & Visual Science July 2008, Vol.49, 2829-2837. doi:https://doi.org/10.1167/iovs.07-1438
Human RPE Melanosomes Protect from Photosensitized and Iron-Mediated Oxidation but Become Pro-oxidant in the Presence of Iron upon Photodegradation Free
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Bartosz Różanowski; Janice M. Burke; Michael E. Boulton; Tadeusz Sarna; Małgorzata Różanowska
Tags: iron, melanins, melanosomes, oxidation, phototoxic dermatitis
Investigative Ophthalmology & Visual Science July 2008, Vol.49, 2838-2847. doi:https://doi.org/10.1167/iovs.08-1700
Mitochondrial Proteomics of the Retinal Pigment Epithelium at Progressive Stages of Age-Related Macular Degeneration Free
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Curtis L. Nordgaard; Pabalu P. Karunadharma; Xiao Feng; Timothy W. Olsen; Deborah A. Ferrington
Tags: age-related macular degeneration, mitochondria, proteins, proteomics, retinal pigment epithelium
Investigative Ophthalmology & Visual Science July 2008, Vol.49, 2848-2855. doi:https://doi.org/10.1167/iovs.07-1352
Secretoglobins: Lacrimal Gland–Specific Rabbit Lipophilin mRNAs Free
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Susann G. Remington; Jean M. Crow; J. Daniel Nelson
Tags: lacrimal gland, oryctolagus cuniculus, rna, polymerase chain reaction, gel
Investigative Ophthalmology & Visual Science July 2008, Vol.49, 2856-2862. doi:https://doi.org/10.1167/iovs.07-1496
Genetic Modifiers of Retinal Degeneration in the rd3 Mouse Free
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Michael Danciger; Diego Ogando; Haidong Yang; Michael T. Matthes; Nicole Yu; Kelly Ahern; Douglas Yasumura; Robert W. Williams; Matthew M. LaVail
Tags: genetics, mice, retinal degeneration, quantitative trait loci, genes
Investigative Ophthalmology & Visual Science July 2008, Vol.49, 2863-2869. doi:https://doi.org/10.1167/iovs.08-1715
Versican and Fibrillin-1 Form a Major Hyaluronan-Binding Complex in the Ciliary Body Free
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Akiko Ohno-Jinno; Zenzo Isogai; Masahiko Yoneda; Kenji Kasai; Osamu Miyaishi; Yoko Inoue; Takuya Kataoka; Jing-Song Zhao; Huili Li; Masayuki Takeyama; Douglas R. Keene; Lynn Y. Sakai; Koji Kimata; Masayoshi Iwaki; Masahiro Zako
Tags: chickens, ciliary body, fibrillins, hyaluronan, antibodies
Investigative Ophthalmology & Visual Science July 2008, Vol.49, 2870-2877. doi:https://doi.org/10.1167/iovs.07-1488
The Leber Congenital Amaurosis Protein AIPL1 Functions as Part of a Chaperone Heterocomplex Free
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Juan Hidalgo-de-Quintana; R. Jane Evans; Michael E. Cheetham; Jacqueline van der Spuy
Tags: heat-shock proteins 70, hsp90 heat-shock proteins, molecular chaperones, proteins, leber's amaurosis
Investigative Ophthalmology & Visual Science July 2008, Vol.49, 2878-2887. doi:https://doi.org/10.1167/iovs.07-1576

Clinical and Epidemiologic Research

Visual Disability, Visual Function, and Myopia among Rural Chinese Secondary School Children: The Xichang Pediatric Refractive Error Study (X-PRES)—Report 1 Free
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Nathan Congdon; Yunfei Wang; Yue Song; Kai Choi; Mingzhi Zhang; Zhongxia Zhou; Zhenling Xie; Liping Li; Xueyu Liu; Abhishek Sharma; Bin Wu; Dennis S. C. Lam
Tags: child, chinese (other dialects), chinese people, disability, myopia
Investigative Ophthalmology & Visual Science July 2008, Vol.49, 2888-2894. doi:https://doi.org/10.1167/iovs.07-1160
Spectacle Acceptance among Secondary School Students in Rural China: The Xichang Pediatric Refractive Error Study (X-PRES)—Report 5 Free
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Liping Li; Yue Song; Xiaojian Liu; Bei Lu; Kai Choi; Dennis S. C. Lam; Mingzhi Zhang; Mingwei Zheng; Yunfei Wang; Abhishek Sharma; Nathan Congdon
Tags: child, china, eyeglasses, pediatrics, pressure-physical agent
Investigative Ophthalmology & Visual Science July 2008, Vol.49, 2895-2902. doi:https://doi.org/10.1167/iovs.07-1531
Role of Near Work in Myopia: Findings in a Sample of Australian School Children Free
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Jenny M. Ip; Seang-Mei Saw; Kathryn A. Rose; Ian G. Morgan; Annette Kifley; Jie Jin Wang; Paul Mitchell
Tags: myopia, child, reading (activity), school-age child, school (environment)
Investigative Ophthalmology & Visual Science July 2008, Vol.49, 2903-2910. doi:https://doi.org/10.1167/iovs.07-0804
Diurnal Variation of Axial Length, Intraocular Pressure, and Anterior Eye Biometrics Free
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Scott A. Read; Michael J. Collins; D. Robert Iskander
Tags: biometry, circadian rhythms, eye, intraocular pressure, cornea
Investigative Ophthalmology & Visual Science July 2008, Vol.49, 2911-2918. doi:https://doi.org/10.1167/iovs.08-1833
Minus-Lens–Stimulated Accommodative Amplitude Decreases Sigmoidally with Age: A Study of Objectively Measured Accommodative Amplitudes from Age 3 Free
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Heather A. Anderson; Gloria Hentz; Adrian Glasser; Karla K. Stuebing; Ruth E. Manny
Tags: lens (device), lens, crystalline, visual accommodation, child
Investigative Ophthalmology & Visual Science July 2008, Vol.49, 2919-2926. doi:https://doi.org/10.1167/iovs.07-1492

Cornea

Association of Protein Tyrosine Phosphatases (PTPs)-1B with c-Met Receptor and Modulation of Corneal Epithelial Wound Healing Free
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Azucena Kakazu; Guru Sharma; Haydee E. P. Bazan
Tags: cornea, epithelium, met gene, protein tyrosine phosphatase, wound healing
Investigative Ophthalmology & Visual Science July 2008, Vol.49, 2927-2935. doi:https://doi.org/10.1167/iovs.07-0709
Epidermal Growth Factor Synergism with TGF-β1 via PI-3 Kinase Activity in Corneal Keratocyte Differentiation Free
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Jiucheng He; Haydee E. P. Bazan
Tags: 1-phosphatidylinositol 3-kinase, cornea, epidermal growth factor, keratocytes, western blotting
Investigative Ophthalmology & Visual Science July 2008, Vol.49, 2936-2945. doi:https://doi.org/10.1167/iovs.07-0900
Increased Clusterin Expression in Fuchs’ Endothelial Dystrophy Free
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Ula V. Jurkunas; Maya S. Bitar; Ian Rawe; Deshea L. Harris; Kathryn Colby; Nancy C. Joyce
Tags: clu gene, clusterin, fuchs' endothelial dystrophy, proteins, western blotting
Investigative Ophthalmology & Visual Science July 2008, Vol.49, 2946-2955. doi:https://doi.org/10.1167/iovs.07-1405
Decreased Expression of Peroxiredoxins in Fuchs’ Endothelial Dystrophy Free
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Ula V. Jurkunas; Ian Rawe; Maya S. Bitar; Cheng Zhu; Deshea L. Harris; Kathryn Colby; Nancy C. Joyce
Tags: cornea, fuchs' endothelial dystrophy, gel, polymerase chain reaction, protein isoforms
Investigative Ophthalmology & Visual Science July 2008, Vol.49, 2956-2963. doi:https://doi.org/10.1167/iovs.07-1529
Laser Scanning In Vivo Confocal Microscopy Reveals Reduced Innervation and Reduction in Cell Density in All Layers of the Keratoconic Cornea Free
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Rachael L. Niederer; Divya Perumal; Trevor Sherwin; Charles N. J. McGhee
Tags: cornea, eye, keratoconus, lasers, microscopy, confocal
Investigative Ophthalmology & Visual Science July 2008, Vol.49, 2964-2970. doi:https://doi.org/10.1167/iovs.07-0968
Conjunctival and Corneal Pneumatic Sensitivity Is Associated with Signs and Symptoms of Ocular Dryness Free
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Ping Situ; Trefford L. Simpson; Desmond Fonn; Lyndon W. Jones
Tags: conjunctiva, cornea, signs and symptoms, dry eye syndromes
Investigative Ophthalmology & Visual Science July 2008, Vol.49, 2971-2976. doi:https://doi.org/10.1167/iovs.08-1734

Eye Movements, Strabismus, Amblyopia and Neuro-ophthalmology

Task-Induced Stress and Motivation Decrease Foveation-Period Durations in Infantile Nystagmus Syndrome Free
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Kwang M. Cham; Andrew J. Anderson; Larry A. Abel
Tags: motivation, pathologic nystagmus, stress, syndrome, waveforms
Investigative Ophthalmology & Visual Science July 2008, Vol.49, 2977-2984. doi:https://doi.org/10.1167/iovs.07-1626
A Primate Model of Nonarteritic Anterior Ischemic Optic Neuropathy Free
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Celia S. Chen; Mary A. Johnson; Robert A. Flower; Bernard J. Slater; Neil R. Miller; Steven L. Bernstein
Tags: eye, nonarteritic anterior ischemic optic neuropathy, primates, magnetic resonance imaging, electrophysiology
Investigative Ophthalmology & Visual Science July 2008, Vol.49, 2985-2992. doi:https://doi.org/10.1167/iovs.07-1651

Glaucoma

Controlled Delivery of 5-Chlorouracil Using Poly(Ortho Esters) in Filtering Surgery for Glaucoma Free
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Marianne Berdugo Polak; Fatemeh Valamanesh; Olivia Felt; Alicia Torriglia; Jean-Claude Jeanny; Jean-Louis Bourges; Patrice Rat; Aoife Thomas-Doyle; David BenEzra; Robert Gurny; Francine Behar-Cohen
Tags: esters, filtering surgery, fluorouracil, glaucoma, oryctolagus cuniculus
Investigative Ophthalmology & Visual Science July 2008, Vol.49, 2993-3003. doi:https://doi.org/10.1167/iovs.07-0919
Contribution of TRPV1 to Microglia-Derived IL-6 and NFκB Translocation with Elevated Hydrostatic Pressure Free
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Rebecca M. Sappington; David J. Calkins
Tags: interleukin-6, microglia, translocation (genetics), trpv1 receptor, hydrostatic pressure
Investigative Ophthalmology & Visual Science July 2008, Vol.49, 3004-3017. doi:https://doi.org/10.1167/iovs.07-1355
Mapping Standard Automated Perimetry to the Peripapillary Retinal Nerve Fiber Layer in Glaucoma Free
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Antonio Ferreras; Luís E. Pablo; David F. Garway-Heath; Paolo Fogagnolo; Julián García-Feijoo
Tags: glaucoma, perimetry, retinal nerve fiber layer
Investigative Ophthalmology & Visual Science July 2008, Vol.49, 3018-3025. doi:https://doi.org/10.1167/iovs.08-1775
Effect of Repeated IOP Challenge on Rat Retinal Function Free
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Zheng He; Bang V. Bui; Algis J. Vingrys
Tags: intraocular pressure, recovery of function
Investigative Ophthalmology & Visual Science July 2008, Vol.49, 3026-3034. doi:https://doi.org/10.1167/iovs.07-1628
Glaucoma and On-Road Driving Performance Free
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Sharon A. Haymes; Raymond P. LeBlanc; Marcelo T. Nicolela; Lorraine A. Chiasson; Balwantray C. Chauhan
Tags: glaucoma, vision
Investigative Ophthalmology & Visual Science July 2008, Vol.49, 3035-3041. doi:https://doi.org/10.1167/iovs.07-1609
Conjunctival Modifications in Ocular Hypertension and Primary Open Angle Glaucoma: An In Vivo Confocal Microscopy Study Free
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Marco Ciancaglini; Paolo Carpineto; Luca Agnifili; Mario Nubile; Vincenzo Fasanella; Leonardo Mastropasqua
Tags: conjunctiva, eye, glaucoma, microscopy, confocal, ocular hypertension
Investigative Ophthalmology & Visual Science July 2008, Vol.49, 3042-3048. doi:https://doi.org/10.1167/iovs.07-1201
Development and Evaluation of a Contrast Sensitivity Perimetry Test for Patients with Glaucoma Free
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Aliya Hot; Mitchell W. Dul; William H. Swanson
Tags: contrast sensitivity, glaucoma, perimetry
Investigative Ophthalmology & Visual Science July 2008, Vol.49, 3049-3057. doi:https://doi.org/10.1167/iovs.07-1205

Immunology and Microbiology

Upregulated IL-23 and IL-17 in Behçet Patients with Active Uveitis Free
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Wei Chi; Xuefei Zhu; Peizeng Yang; Xiaoli Liu; Xiaomin Lin; Hongyan Zhou; Xiangkun Huang; Aize Kijlstra
Tags: interleukin-17, interleukin-23, uveitis, behcet syndrome
Investigative Ophthalmology & Visual Science July 2008, Vol.49, 3058-3064. doi:https://doi.org/10.1167/iovs.07-1390

Physiology and Pharmacology

Metabotropic Receptor-Activated Calcium Increases and Store-Operated Calcium Influx in Mouse Müller Cells Free
PDF
Noel Da Silva; Caroline E. Herron; Kelly Stevens; Christine A. B. Jollimore; Steven Barnes; Melanie E. M. Kelly
Tags: calcium, mice, muscarinic acetylcholine receptor, cations, cell culture techniques
Investigative Ophthalmology & Visual Science July 2008, Vol.49, 3065-3073. doi:https://doi.org/10.1167/iovs.07-1118
Determining the Pharmacological Activity of Physalis peruviana Fruit Juice on Rabbit Eyes and Fibroblast Primary Cultures Free
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Juan Manuel Pardo; Marta Raquel Fontanilla; Luis Fernando Ospina; Lady Espinosa
Tags: anti-inflammatory agents, draize test, eye, fibroblasts, fruit juice
Investigative Ophthalmology & Visual Science July 2008, Vol.49, 3074-3079. doi:https://doi.org/10.1167/iovs.07-0633
Effect of Intravitreal Administration of Somatostatin and sst2 Analogs on AMPA-Induced Neurotoxicity in Rat Retina Free
PDF
Foteini Kiagiadaki; Kyriaki Thermos
Tags: alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid, retina, somatostatin, khat
Investigative Ophthalmology & Visual Science July 2008, Vol.49, 3080-3089. doi:https://doi.org/10.1167/iovs.07-1644

Retina

Genotype–Phenotype Correlations for Exudative Age-Related Macular Degeneration Associated with Homozygous HTRA1 and CFH Genotypes Free
PDF
Nicolas Leveziel; Jennyfer Zerbib; Florence Richard; Giuseppe Querques; Gilles Morineau; Veronique Fremeaux-Bacchi; Gabriel Coscas; Gisèle Soubrane; Pascale Benlian; Eric H. Souied
Tags: choroidal neovascularization, exudative age-related macular degeneration, genotype, genotype-phenotype associations, homozygote
Investigative Ophthalmology & Visual Science July 2008, Vol.49, 3090-3094. doi:https://doi.org/10.1167/iovs.07-1540
Morphologic Changes in Patients with Geographic Atrophy Assessed with a Novel Spectral OCT–SLO Combination Free
PDF
Ute E. K. Wolf-Schnurrbusch; Volker Enzmann; Christian K. Brinkmann; Sebastian Wolf
Tags: atrophy, eye, retina, atrophic condition of skin
Investigative Ophthalmology & Visual Science July 2008, Vol.49, 3095-3099. doi:https://doi.org/10.1167/iovs.07-1460
Coagulation Gene Predictors of Photodynamic Therapy for Occult Choroidal Neovascularization in Age-Related Macular Degeneration Free
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Francesco Parmeggiani; Ciro Costagliola; Donato Gemmati; Sergio D'Angelo; Paolo Perri; Claudio Campa; Linda Catozzi; Federica Federici; Adolfo Sebastiani; Carlo Incorvaia
Tags: age-related macular degeneration, choroidal neovascularization, genes, photochemotherapy, blood coagulation
Investigative Ophthalmology & Visual Science July 2008, Vol.49, 3100-3106. doi:https://doi.org/10.1167/iovs.07-1654
Neutralizing VEGF Decreases Tortuosity and Alters Endothelial Cell Division Orientation in Arterioles and Veins in a Rat Model of ROP: Relevance to Plus Disease Free
PDF
M. Elizabeth Hartnett; David Martiniuk; Grace Byfield; Pete Geisen; Gefei Zeng; Victoria L. Bautch
Tags: arteriole, endothelial cells, vascular endothelial growth factor a, nitric oxide synthase, neutralizing antibodies
Investigative Ophthalmology & Visual Science July 2008, Vol.49, 3107-3114. doi:https://doi.org/10.1167/iovs.08-1780
Quantitative Subanalysis of Optical Coherence Tomography after Treatment with Ranibizumab for Neovascular Age-Related Macular Degeneration Free
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Pearse A. Keane; Sandra Liakopoulos; Sharel C. Ongchin; Florian M. Heussen; Sandeep Msutta; Karen T. Chang; Alexander C. Walsh; Srinivas R. Sadda
Tags: aftercare, exudative age-related macular degeneration, optical coherence tomography, ranibizumab, volume
Investigative Ophthalmology & Visual Science July 2008, Vol.49, 3115-3120. doi:https://doi.org/10.1167/iovs.08-1689
Focal Macular Electroretinograms in Eyes with Wet-type Age-Related Macular Degeneration Free
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Hiroaki Nishihara; Mineo Kondo; Kohei Ishikawa; Tadasu Sugita; Chang-Hua Piao; Yoshiharu Nakamura; Hiroko Terasaki
Tags: age-related macular degeneration, electroretinography, eye, visual acuity, wave - physical agent
Investigative Ophthalmology & Visual Science July 2008, Vol.49, 3121-3125. doi:https://doi.org/10.1167/iovs.08-1835
Prevalence and Associated Risk Factors of Age-Related Macular Degeneration in an Elderly Chinese Population in Taiwan: The Shihpai Eye Study Free
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Shih-Jen Chen; Ching-Yu Cheng; Kai-Ling Peng; An-Fei Li; Wen-Ming Hsu; Jorn-Hon Liu; Pesus Chou
Tags: age-related macular degeneration, chinese people, eye, older adult, prevalence
Investigative Ophthalmology & Visual Science July 2008, Vol.49, 3126-3133. doi:https://doi.org/10.1167/iovs.08-1803
Isolated Ocular Disease Is Associated with Decreased Mucolipin-1 Channel Conductance Free
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Ehud Goldin; Rafael C. Caruso; William Benko; Christine R. Kaneski; Stephanie Stahl; Raphael Schiffmann
Tags: electroretinography, eye diseases, ion channels, mutation, proteins
Investigative Ophthalmology & Visual Science July 2008, Vol.49, 3134-3142. doi:https://doi.org/10.1167/iovs.07-1649
Evidence of Retinal Function Using Microperimetry following Autologous Retinal Pigment Epithelium-Choroid Graft in Macular Dystrophy Free
PDF
Fred K. Chen; Gurmit S. Uppal; Gary S. Rubin; Andrew R. Webster; Peter J. Coffey; Lyndon Da Cruz
Tags: choroid, epithelium, macular dystrophy, pigment, surgical procedures, operative
Investigative Ophthalmology & Visual Science July 2008, Vol.49, 3143-3150. doi:https://doi.org/10.1167/iovs.07-1648
TEM7 (PLXDC1) in Neovascular Endothelial Cells of Fibrovascular Membranes from Patients with Proliferative Diabetic Retinopathy Free
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Yoko Yamaji; Shigeo Yoshida; Keijiro Ishikawa; Akihito Sengoku; Kota Sato; Ayako Yoshida; Rumi Kuwahara; Kenoki Ohuchida; Eiji Oki; Hiroshi Enaida; Kimihiko Fujisawa; Toshihiro Kono; Tatsuro Ishibashi
Tags: endothelial cells, polymerase chain reaction, proliferative diabetic retinopathy, tissue membrane, proteins
Investigative Ophthalmology & Visual Science July 2008, Vol.49, 3151-3157. doi:https://doi.org/10.1167/iovs.07-1249
Photodynamic Therapy in Retinoblastoma: Effects of Verteporfin on Retinoblastoma Cell Lines Free
PDF
Harald Stephan; Réka Boeloeni; Angelika Eggert; Norbert Bornfeld; Andreas Schueler
Tags: cell lines, retinoblastoma, verteporfin, photochemotherapy
Investigative Ophthalmology & Visual Science July 2008, Vol.49, 3158-3163. doi:https://doi.org/10.1167/iovs.07-1016
Effects of Bevacizumab (Avastin) on Retinal Cells in Organotypic Culture Free
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Stefanie Kaempf; Sandra Johnen; Anna Katharina Salz; Andreas Weinberger; Peter Walter; Gabriele Thumann
Tags: bevacizumab
Investigative Ophthalmology & Visual Science July 2008, Vol.49, 3164-3171. doi:https://doi.org/10.1167/iovs.07-1265
Carrier of R14W in Carbonic Anhydrase IV Presents Bothnia Dystrophy Phenotype Caused by Two Allelic Mutations in RLBP1 Free
PDF
Linda Köhn; Marie S. I. Burstedt; Frida Jonsson; Konstantin Kadzhaev; Eneli Haamer; Ola Sandgren; Irina Golovleva
Tags: carbonic anhydrase iv, mutation, phenotype, polymerase chain reaction, dna
Investigative Ophthalmology & Visual Science July 2008, Vol.49, 3172-3177. doi:https://doi.org/10.1167/iovs.07-1664
Ionic Dysregulatory Phenotyping of Pathologic Retinal Thinning with Manganese-Enhanced MRI Free
PDF
Bruce A. Berkowitz; Marius Gradianu; Stephen Schafer; Ying Jin; Andre Porchia; Raymond Iezzi; Robin Roberts
Tags: magnetic resonance imaging, manganese, phenotype determination, tissue degeneration, hypoxia
Investigative Ophthalmology & Visual Science July 2008, Vol.49, 3178-3184. doi:https://doi.org/10.1167/iovs.08-1720
Autologous Transplantation of RPE with Partial-Thickness Choroid after Mechanical Debridement of Bruch Membrane in the Rabbit Free
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Yuntao Hu; Taoran Zhang; Jianguo Wu; Ying Li; Xinrong Lu; Fang Qian; Zhengqin Yin; Zhizhong Ma
Tags: bruch's basal membrane, choroid, mechanical debridement, oryctolagus cuniculus, surgical procedures, operative
Investigative Ophthalmology & Visual Science July 2008, Vol.49, 3185-3192. doi:https://doi.org/10.1167/iovs.07-1299
Interleukin-6 as a Photoreceptor Neuroprotectant in an Experimental Model of Retinal Detachment Free
PDF
Deborah Y. Chong; Christopher S. Boehlke; Qiong-Duan Zheng; Linda Zhang; Ying Han; David N. Zacks
Tags: interleukin-6, neuroprotective agents, photoreceptors, retinal detachment, in situ nick-end labeling
Investigative Ophthalmology & Visual Science July 2008, Vol.49, 3193-3200. doi:https://doi.org/10.1167/iovs.07-1641
Long-term Vision Rescue by Human Neural Progenitors in a Rat Model of Photoreceptor Degeneration Free
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Shaomei Wang; Sergej Girman; Bin Lu; Nicholas Bischoff; Toby Holmes; Rebecca Shearer; Lynda S. Wright; Clive N. Svendsen; David M. Gamm; Raymond D. Lund
Tags: luminance, photoreceptors, proto-oncogene proteins c-abl, tissue degeneration, vision
Investigative Ophthalmology & Visual Science July 2008, Vol.49, 3201-3206. doi:https://doi.org/10.1167/iovs.08-1831

Retinal Cell Biology

Selective Degeneration of Central Photoreceptors after Hyperbaric Oxygen in Normal and Metallothionein-Knockout Mice Free
PDF
Michele Nachman-Clewner; Frank J. Giblin; C. Kathleen Dorey; Robert H. I. Blanks; Loan Dang; Christopher J. Dougherty; Janet C. Blanks
Tags: hyperbaric oxygenation, metallothionein, mice, photoreceptors, retina
Investigative Ophthalmology & Visual Science July 2008, Vol.49, 3207-3215. doi:https://doi.org/10.1167/iovs.07-1039
Role of the Polyol Pathway in High Glucose–Induced Apoptosis of Retinal Pericytes and Proliferation of Endothelial Cells Free
PDF
Yoshihiro Takamura; Takeshi Tomomatsu; Eri Kubo; Syousai Tsuzuki; Yoshio Akagi
Tags: electroconvulsive therapy, epidural cortical stimulation, glucose, pericytes, apoptosis
Investigative Ophthalmology & Visual Science July 2008, Vol.49, 3216-3223. doi:https://doi.org/10.1167/iovs.07-1643
A High-Throughput Screening Method for Small-Molecule Pharmacologic Chaperones of Misfolded Rhodopsin Free
PDF
Syed M. Noorwez; David A. Ostrov; J. Hugh McDowell; Mark P. Krebs; Shalesh Kaushal
Tags: high-throughput screening methods, opsin, pharmacology, rhodopsin, small molecule
Investigative Ophthalmology & Visual Science July 2008, Vol.49, 3224-3230. doi:https://doi.org/10.1167/iovs.07-1539
Role of NADPH Oxidase and Stat3 in Statin-Mediated Protection against Diabetic Retinopathy Free
PDF
Mohamed Al-Shabrawey; Manuela Bartoli; Azza B. El-Remessy; Guochuan Ma; Suraporn Matragoon; Tahira Lemtalsi; R. William Caldwell; Ruth B. Caldwell
Tags: diabetes mellitus, diabetic retinopathy, nadph oxidases, simvastatin, stat3 protein
Investigative Ophthalmology & Visual Science July 2008, Vol.49, 3231-3238. doi:https://doi.org/10.1167/iovs.08-1754
Role of NADPH Oxidase in Retinal Vascular Inflammation Free
PDF
Mohamed Al-Shabrawey; Modesto Rojas; Tammy Sanders; Ali Behzadian; Azza El-Remessy; Manuela Bartoli; Abdul Kader Parpia; Gregory Liou; Ruth B. Caldwell
Tags: cybb gene, diabetes mellitus, inflammation, intercellular adhesion molecule 1, leukocyte cell adhesion
Investigative Ophthalmology & Visual Science July 2008, Vol.49, 3239-3244. doi:https://doi.org/10.1167/iovs.08-1755
Involvement of OA1, an Intracellular GPCR, and Gαi3, Its Binding Protein, in Melanosomal Biogenesis and Optic Pathway Formation Free
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Alejandra Young; Elisabeth B. Powelson; Irene E. Whitney; Mary A. Raven; Steven Nusinowitz; Meisheng Jiang; Lutz Birnbaumer; Benjamin E. Reese; Debora B. Farber
Tags: carrier proteins, electroretinography, eye, g-protein-coupled receptors, melanosomes
Investigative Ophthalmology & Visual Science July 2008, Vol.49, 3245-3252. doi:https://doi.org/10.1167/iovs.08-1806

Visual Psychophysics and Physiological Optics

Increased Role of Peripheral Vision in Self-Induced Motion in Patients with Age-Related Macular Degeneration Free
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Luminita Tarita-Nistor; Esther G. González; Samuel N. Markowitz; Linda Lillakas; Martin J. Steinbach
Tags: age-related macular degeneration, motion, peripheral vision, scotoma
Investigative Ophthalmology & Visual Science July 2008, Vol.49, 3253-3258. doi:https://doi.org/10.1167/iovs.07-1290

Clinical Trials

Effect of Progressive Addition Lenses on Myopia Progression in Japanese Children: A Prospective, Randomized, Double-Masked, Crossover Trial Free
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Satoshi Hasebe; Hiroshi Ohtsuki; Takafumi Nonaka; Chiaki Nakatsuka; Manabu Miyata; Ichiro Hamasaki; Shuhei Kimura
Tags: child, lens (device), lens, crystalline, myopia, papillon-lefevre disease
Investigative Ophthalmology & Visual Science July 2008, Vol.49, 2781-2789. doi:https://doi.org/10.1167/iovs.07-0385

Erratum

ERRATUM Free
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Investigative Ophthalmology & Visual Science July 2008, Vol.49, 2805. doi:
Copyright © 2025 Association for Research in Vision and Ophthalmology.
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