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Anatomy and Pathology/Oncology

Whole-Genome Microarray Detects Deletions and Loss of Heterozygosity of Chromosome 3 Occurring Exclusively in Metastasizing Uveal Melanoma Free
PDF
Sarah L. Lake; Sarah E. Coupland; Azzam F. G. Taktak; Bertil E. Damato
Tags: chromosomes, human, pair 3, genes, genome, loss of heterozygosity, neoplasms
Investigative Ophthalmology & Visual Science October 2010, Vol.51, 4884-4891. doi:https://doi.org/10.1167/iovs.09-5083
CT Based Three-Dimensional Measurement of Orbit and Eye Anthropometry Free
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Ashley A. Weaver; Kathryn L. Loftis; Josh C. Tan; Stefan M. Duma; Joel D. Stitzel
Tags: anthropometry, eye, orbit
Investigative Ophthalmology & Visual Science October 2010, Vol.51, 4892-4897. doi:https://doi.org/10.1167/iovs.10-5503
Genetic Heterogeneity in Uveal Melanoma Assessed by Multiplex Ligation-Dependent Probe Amplification Free
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Justyna Dopierala; Bertil E. Damato; Sarah L. Lake; Azzam F. G. Taktak; Sarah E. Coupland
Tags: amplification, genetic heterogeneity, heterogeneity, ligation, neoplasms
Investigative Ophthalmology & Visual Science October 2010, Vol.51, 4898-4905. doi:https://doi.org/10.1167/iovs.09-5004

Biochemistry and Molecular Biology

Leber's Hereditary Optic Neuropathy Affects Only Female Matrilineal Relatives in Two Chinese Families Free
PDF
Jia Qu; Ying Wang; Yi Tong; Xiangtian Zhou; Fuxin Zhao; Li Yang; Shoukang Zhang; Juanjuan Zhang; Constance E. West; Min-Xin Guan
Tags: chinese (other dialects), chinese people, family, genetic pedigree, optic atrophy, hereditary, leber
Investigative Ophthalmology & Visual Science October 2010, Vol.51, 4906-4912. doi:https://doi.org/10.1167/iovs.09-5027
Retinal Pigment Epithelium Defects Accelerate Photoreceptor Degeneration in Cell Type–Specific Knockout Mouse Models of Choroideremia Free
PDF
Tanya Tolmachova; Silene T. Wavre-Shapton; Alun R. Barnard; Robert E. MacLaren; Clare E. Futter; Miguel C. Seabra
Tags: choroideremia, mice, mice, knockout, photoreceptors, retinal pigment epithelium
Investigative Ophthalmology & Visual Science October 2010, Vol.51, 4913-4920. doi:https://doi.org/10.1167/iovs.09-4892
Proteome Analysis of Human Aqueous Humor Free
PDF
Uttio Roy Chowdhury; Benjamin J. Madden; Mary Christine Charlesworth; Michael P. Fautsch
Tags: aqueous humor, cytokine, proteins, proteome, growth factor
Investigative Ophthalmology & Visual Science October 2010, Vol.51, 4921-4931. doi:https://doi.org/10.1167/iovs.10-5531
An Intergenic Region between the tagSNP rs3793917 and rs11200638 in the HTRA1 Gene Indicates Association with Age-Related Macular Degeneration Free
PDF
Andrea J. Richardson; F. M. Amirul Islam; Khin Zaw Aung; Robyn H. Guymer; Paul N. Baird
Tags: age-related macular degeneration, htra1 gene, single nucleotide polymorphism, genes
Investigative Ophthalmology & Visual Science October 2010, Vol.51, 4932-4936. doi:https://doi.org/10.1167/iovs.09-5114
Variations in NTF4, VAV2, and VAV3 Genes Are Not Involved with Primary Open-Angle and Primary Angle-Closure Glaucomas in an Indian Population Free
PDF
Kollu N. Rao; Inderjeet Kaur; Rajul S. Parikh; Anil K. Mandal; Garudadri Chandrasekhar; Ravi Thomas; Subhabrata Chakrabarti
Tags: angle closure glaucoma, genes, ntf5 gene, open-angle glaucoma, screening
Investigative Ophthalmology & Visual Science October 2010, Vol.51, 4937-4941. doi:https://doi.org/10.1167/iovs.10-5553
7-Ketocholesterol–Induced Inflammation: Involvement of Multiple Kinase Signaling Pathways via NFκB but Independently of Reactive Oxygen Species Formation Free
PDF
Ignacio M. Larrayoz; Jiahn-Dar Huang; Jung Wha Lee; Iranzu Pascual; Ignacio R. Rodríguez
Tags: cytokine, inflammation, interleukin-6, interleukin-8, mitogen-activated protein kinases
Investigative Ophthalmology & Visual Science October 2010, Vol.51, 4942-4955. doi:https://doi.org/10.1167/iovs.09-4854

Clinical and Epidemiologic Research

Infrared Fundus Autofluorescence and Central Serous Chorioretinopathy Free
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Tetsuju Sekiryu; Tomohiro Iida; Ichiro Maruko; Kuniharu Saito; Takeshi Kondo
Tags: central serous chorioretinopathy, eye, fundus autofluorescence imaging, melanins, diagnostic imaging
Investigative Ophthalmology & Visual Science October 2010, Vol.51, 4956-4962. doi:https://doi.org/10.1167/iovs.09-5009
The Epidemiology and Socioeconomic Associations of Retinal Detachment in Scotland: A Two-Year Prospective Population-Based Study Free
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Danny Mitry; David G. Charteris; David Yorston; M. A. Rehman Siddiqui; Harry Campbell; Anna-Louise Murphy; Brian W. Fleck; Alan F. Wright; Jaswinder Singh; the Scottish RD Study Group
Tags: epidemiology, incidence, radiation recall dermatitis, retinal detachment, scotland
Investigative Ophthalmology & Visual Science October 2010, Vol.51, 4963-4968. doi:https://doi.org/10.1167/iovs.10-5400
Population Density and Refractive Error among Chinese Children Free
PDF
Mingzhi Zhang; Liping Li; Lizhen Chen; Jack Lee; Jiasi Wu; Amy Yang; Connie Chen; Daocheng Xu; Dennis S. C. Lam; Abhishek Sharma; Sian Griffiths; Yang Gao; Nathan Congdon
Tags: child, chinese (other dialects), chinese people, myopia, population density
Investigative Ophthalmology & Visual Science October 2010, Vol.51, 4969-4976. doi:https://doi.org/10.1167/iovs.10-5424
Impact of Ethnicity on the Correlation of Retinal Parameters with Axial Length Free
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Yasser M. Tariq; Chameen Samarawickrama; Amy Pai; George Burlutsky; Paul Mitchell
Tags: ethnic group, retinal nerve fiber layer, child, european continental ancestry group, asian
Investigative Ophthalmology & Visual Science October 2010, Vol.51, 4977-4982. doi:https://doi.org/10.1167/iovs.10-5226
New-Onset Maternal Gestational Hypertension and Risk of Retinopathy of Prematurity Free
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Mohamed A. Zayed; Abhineet Uppal; M. Elizabeth Hartnett
Tags: hypertension, pregnancy-induced, infant, mothers, retinopathy of prematurity, birth weight
Investigative Ophthalmology & Visual Science October 2010, Vol.51, 4983-4988. doi:https://doi.org/10.1167/iovs.10-5283
Association of Matrix Metalloproteinase Gene Polymorphisms with Refractive Error in Amish and Ashkenazi Families Free
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Robert Wojciechowski; Joan E. Bailey-Wilson; Dwight Stambolian
Tags: family, genes, matrix metalloproteinases, polymorphism, refractive errors
Investigative Ophthalmology & Visual Science October 2010, Vol.51, 4989-4995. doi:https://doi.org/10.1167/iovs.10-5474
Trichiasis Surgery in The Gambia: A 4-Year Prospective Study Free
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Saul N. Rajak; Pateh Makalo; Ansumana Sillah; Martin J. Holland; David C. W. Mabey; Robin L. Bailey; Matthew J. Burton
Tags: eyelid trichiasis, gambia, prospective studies, recurrence, surgical procedures, operative
Investigative Ophthalmology & Visual Science October 2010, Vol.51, 4996-5001. doi:https://doi.org/10.1167/iovs.10-5169

Cornea

TGF-β–Stimulated CTGF Production Enhanced by Collagen and Associated with Biogenesis of a Novel 31-kDa CTGF Form in Human Corneal Fibroblasts Free
PDF
Edward G. Tall; Audrey M. Bernstein; Noelynn Oliver; Julia L. Gray; Sandra K. Masur
Tags: connective tissue growth factor, fibroblasts, cornea, collagen
Investigative Ophthalmology & Visual Science October 2010, Vol.51, 5002-5011. doi:https://doi.org/10.1167/iovs.09-5110
Upregulation of Matrix Metalloproteinase Expression by Poly(I:C) in Corneal Fibroblasts: Role of NF-κB and Interleukin-1β Free
PDF
Kazuhiro Kimura; Tomoko Orita; Yukiko Kondo; Hongyan Zhou; Teruo Nishida
Tags: cornea, fibroblasts, interstitial collagenase, matrix metalloproteinases, stromelysin 1
Investigative Ophthalmology & Visual Science October 2010, Vol.51, 5012-5018. doi:https://doi.org/10.1167/iovs.10-5167
Increased Expression of Cathepsins and Obesity-Induced Proinflammatory Cytokines in Lacrimal Glands of Male NOD Mouse Free
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Xiaodong Li; Kaijin Wu; Maria Edman; Katja Schenke-Layland; Michelle MacVeigh-Aloni; Srikanth Reddy Janga; Barbara Schulz; Sarah F. Hamm-Alvarez
Tags: adaptive testing, cathepsins, cats, cytokine, langer-giedion syndrome
Investigative Ophthalmology & Visual Science October 2010, Vol.51, 5019-5029. doi:https://doi.org/10.1167/iovs.09-4523
Posterior Linear Stromal Haze Formation after Simultaneous Photorefractive Keratectomy followed by Corneal Collagen Cross-linking Free
PDF
George D. Kymionis; Dimitra M. Portaliou; Vasilios F. Diakonis; Georgios A. Kontadakis; Maria S. Krasia; Anastasios G. Papadiamantis; Efekan Coskunseven; Aristofanis I. Pallikaris
Tags: cornea, corneal collagen cross-linking, corneal opacity, microscopy, confocal, surgical procedures, operative
Investigative Ophthalmology & Visual Science October 2010, Vol.51, 5030-5033. doi:https://doi.org/10.1167/iovs.09-5105
Effect of Hypoxic Stress–Activated Polo-like Kinase 3 on Corneal Epithelial Wound Healing Free
PDF
Jiawei Lu; Ling Wang; Wei Dai; Luo Lu
Tags: cornea, epithelium, hypoxia, stress, wound healing
Investigative Ophthalmology & Visual Science October 2010, Vol.51, 5034-5040. doi:https://doi.org/10.1167/iovs.10-5501

Eye Movements, Strabismus, Amblyopia and Neuro-ophthalmology

Electrophysiological Detection of Delayed Postretinal Neural Conduction in Human Amblyopia Free
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Vincenzo Parisi; Maria Elisa Scarale; Nicole Balducci; Michela Fresina; Emilio C. Campos
Tags: amblyopia, evoked potentials, visual, eye, nerve conduction function, electroretinography
Investigative Ophthalmology & Visual Science October 2010, Vol.51, 5041-5048. doi:https://doi.org/10.1167/iovs.10-5412

Glaucoma

Retinal Nerve Fiber Layer Loss in Glaucoma Patients with a Relative Afferent Pupillary Defect Free
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Shenton S. L. Chew; William J. Cunnningham; Greg D. Gamble; Helen V. Danesh-Meyer
Tags: glaucoma, relative afferent pupillary defect, retinal nerve fiber layer, eye
Investigative Ophthalmology & Visual Science October 2010, Vol.51, 5049-5053. doi:https://doi.org/10.1167/iovs.09-4216
Regulation of Tenon's Capsule Fibroblast Cell Proliferation by the Opioid Growth Factor and the Opioid Growth Factor Receptor Axis Free
PDF
Matthew S. Klocek; Joseph W. Sassani; Renee N. Donahue; Patricia J. McLaughlin; Ian S. Zagon
Tags: cell proliferation, fibroblasts, growth factor, growth factor receptors, necrosis
Investigative Ophthalmology & Visual Science October 2010, Vol.51, 5054-5061. doi:https://doi.org/10.1167/iovs.09-4949
Three-Dimensional Imaging of the Macular Retinal Nerve Fiber Layer in Glaucoma with Spectral-Domain Optical Coherence Tomography Free
PDF
Atsushi Sakamoto; Masanori Hangai; Masayuki Nukada; Hideo Nakanishi; Satoshi Mori; Yuriko Kotera; Ryo Inoue; Nagahisa Yoshimura
Tags: glaucoma, optical coherence tomography, retinal nerve fiber layer, imaging, three-dimensional, eye
Investigative Ophthalmology & Visual Science October 2010, Vol.51, 5062-5070. doi:https://doi.org/10.1167/iovs.09-4954
Oxidative Stress and the Regulation of Complement Activation in Human Glaucoma Free
PDF
Gülgün Tezel; Xiangjun Yang; Cheng Luo; Angela D. Kain; David W. Powell; Markus H. Kuehn; Henry J. Kaplan
Tags: complement activation, complement system proteins, glaucoma, oxidative stress, regulation
Investigative Ophthalmology & Visual Science October 2010, Vol.51, 5071-5082. doi:https://doi.org/10.1167/iovs.10-5289
Qualitative and Quantitative Morphologic Changes in the Vasculature and Extracellular Matrix of the Prelaminar Optic Nerve Head in Eyes with POAG Free
PDF
Ozan-Yueksel Tektas; Elke Lütjen-Drecoll; Michael Scholz
Tags: blood capillaries, capillary bed, eye, open-angle glaucoma, optic disk
Investigative Ophthalmology & Visual Science October 2010, Vol.51, 5083-5091. doi:https://doi.org/10.1167/iovs.09-5101
Histologic Effects of a New Device for High-Intensity Focused Ultrasound Cyclocoagulation Free
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Florent Aptel; Thomas Charrel; Xavier Palazzi; Jean-Yves Chapelon; Philippe Denis; Cyril Lafon
Tags: eye, high-intensity focused ultrasound, necrosis, oryctolagus cuniculus, transducers
Investigative Ophthalmology & Visual Science October 2010, Vol.51, 5092-5098. doi:https://doi.org/10.1167/iovs.09-5135

Immunology and Microbiology

Expression and Function of Inducible Costimulator on Peripheral Blood CD4+ T Cells in Behçet's Patients with Uveitis: A New Activity Marker? Free
PDF
Yoshihiko Usui; Masaru Takeuchi; Naoyuki Yamakawa; Aya Takeuchi; Takeshi Kezuka; Juan Ma; Ryusaku Matsuda; Yoko Okunuki; Hisaya Akiba; Hiroshi Goto
Tags: behcet syndrome, t-lymphocytes, uveitis
Investigative Ophthalmology & Visual Science October 2010, Vol.51, 5099-5104. doi:https://doi.org/10.1167/iovs.10-5286
Prevention of Endotoxin-Induced Uveitis in Rats by Plant Sterol Guggulsterone Free
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Nilesh M. Kalariya; Mohammad Shoeb; Aramati B. M. Reddy; Min Zhang; Frederik J. G. M. van Kuijk; Kota V. Ramana
Tags: cyclooxygenase-2, cyclooxygenase-2 inhibitors, cytokine, endotoxins, eye
Investigative Ophthalmology & Visual Science October 2010, Vol.51, 5105-5113. doi:https://doi.org/10.1167/iovs.09-4873
A Highly Virulent Staphylococcus aureus: Rabbit Anterior Chamber Infection, Characterization, and Genetic Analysis Free
PDF
Charles L. Balzli; John Bartell; Joseph J. Dajcs; Clare C. McCormick; Armando R. Caballero; David Stroman; Richard J. O'Callaghan
Tags: anterior chamber of eye, genetic analysis, infections, oryctolagus cuniculus, staphylococcus aureus
Investigative Ophthalmology & Visual Science October 2010, Vol.51, 5114-5120. doi:https://doi.org/10.1167/iovs.10-5179
The Monocyte Chemokine Receptor CX3CR1 Does Not Play a Significant Role in the Pathogenesis of Experimental Autoimmune Uveoretinitis Free
PDF
Jelena Kezic; Paul G. McMenamin
Tags: autoimmune diseases, autoimmunity, chemokine receptors, chimera organism, mice
Investigative Ophthalmology & Visual Science October 2010, Vol.51, 5121-5127. doi:https://doi.org/10.1167/iovs.10-5325
Characterization of Humoral Immune Responses to Chlamydial HSP60, CPAF, and CT795 in Inflammatory and Severe Trachoma Free
PDF
Troy Skwor; Ram Prasad Kandel; Sunniya Basravi; Aslam Khan; Bassant Sharma; Deborah Dean
Tags: antibodies, chaperonin 60, chlamydia, fusion proteins, immune response
Investigative Ophthalmology & Visual Science October 2010, Vol.51, 5128-5136. doi:https://doi.org/10.1167/iovs.09-5113
Adeno-Associated Virus–Mediated IL-10 Gene Transfer Suppresses Lacrimal Gland Immunopathology in a Rabbit Model of Autoimmune Dacryoadenitis Free
PDF
Padmaja B. Thomas; Deedar M. Samant; Shivaram Selvam; Rui Hua Wei; Yanru Wang; Douglas Stevenson; Joel E. Schechter; Florence Apparailly; Austin K. Mircheff; Melvin D. Trousdale
Tags: autoimmune diseases, autoimmunity, dacryoadenitis, gene transfer techniques, immunopathology specialty
Investigative Ophthalmology & Visual Science October 2010, Vol.51, 5137-5144. doi:https://doi.org/10.1167/iovs.10-5423

Lens

Large-Scale Binding of α-Crystallin to Cell Membranes of Aged Normal Human Lenses: A Phenomenon That Can Be Induced by Mild Thermal Stress Free
PDF
Michael G. Friedrich; Roger J. W. Truscott
Tags: cell membrane, crystallins, lens (device), lens, crystalline, proteins
Investigative Ophthalmology & Visual Science October 2010, Vol.51, 5145-5152. doi:https://doi.org/10.1167/iovs.10-5261
Tissue Localization and Solubilities of αA-crystallin and its Numerous C-terminal Truncation Products in Pre- and Postcataractous ICR/f Rat Lenses Free
PDF
David R. Stella; Kyle A. Floyd; Angus C. Grey; Matthew B. Renfrow; Kevin L. Schey; Stephen Barnes
Tags: body tissue, crystallins, lens (device), lens, crystalline, proteins
Investigative Ophthalmology & Visual Science October 2010, Vol.51, 5153-5161. doi:https://doi.org/10.1167/iovs.10-5302
α- and β-Crystallins Modulate the Head Group Order of Human Lens Membranes during Aging Free
PDF
Xiangjia Zhu; Katharina Gaus; Yi Lu; Astrid Magenau; Roger J. W. Truscott; Todd W. Mitchell
Tags: crystallins, lens (device), lens, crystalline, tissue membrane, proteins
Investigative Ophthalmology & Visual Science October 2010, Vol.51, 5162-5167. doi:https://doi.org/10.1167/iovs.09-4947

Physiology and Pharmacology

ATP-Induced Relaxation of Porcine Retinal Arterioles In Vitro Depends on Prostaglandin E Synthesized in the Perivascular Retinal Tissue Free
PDF
Kim Holmgaard; Toke Bek
Tags: arteriole, body tissue, prostaglandins, prostaglandins e, suidae
Investigative Ophthalmology & Visual Science October 2010, Vol.51, 5168-5175. doi:https://doi.org/10.1167/iovs.09-4608
Cellular Basis for Bimatoprost Effects on Human Conventional Outflow Free
PDF
W. Daniel Stamer; David Piwnica; Thierry Jolas; Robert W. Carling; Clive L. Cornell; Hans Fliri; Jose Martos; Simon N. Pettit; Jenny W. Wang; David F. Woodward
Tags: bimatoprost, spectrum analysis
Investigative Ophthalmology & Visual Science October 2010, Vol.51, 5176-5181. doi:https://doi.org/10.1167/iovs.09-4955
Two-Photon Fluorescence Excitation Microscopy to Assess Transscleral Diffusional Pathways in an Isolated Perfused Bovine Eye Model Free
PDF
Wee Kuan Kek; Wallace S. Foulds; Gail McConnell; Amanda J. Wright; John M. Girkin; Clive G. Wilson
Tags: cattle, excitation, eye, fluorescence, photons
Investigative Ophthalmology & Visual Science October 2010, Vol.51, 5182-5189. doi:https://doi.org/10.1167/iovs.09-3854
Knockdown of NBCe1 In Vivo Compromises the Corneal Endothelial Pump Free
PDF
Cailing Liu; Qiang Cheng; Tracy Nguyen; Joseph A. Bonanno
Tags: cornea, endothelium, oryctolagus cuniculus, eye, brinzolamide ophthalmic suspension
Investigative Ophthalmology & Visual Science October 2010, Vol.51, 5190-5197. doi:https://doi.org/10.1167/iovs.10-5257
Delivery of SAR 1118 to the Retina via Ophthalmic Drops and its Effectiveness in a Rat Streptozotocin (STZ) Model of Diabetic Retinopathy (DR) Free
PDF
Vidhya R. Rao; Elizabeth Prescott; Namdev B. Shelke; Ruchit Trivedi; Peter Thomas; Craig Struble; Tom Gadek; Charles A. O'Neill; Uday B. Kompella
Tags: blood-retinal barrier, diabetes mellitus, diabetic retinopathy, eye, eyedrops
Investigative Ophthalmology & Visual Science October 2010, Vol.51, 5198-5204. doi:https://doi.org/10.1167/iovs.09-5144
Evaluation of Clearance Mechanisms with Transscleral Drug Delivery Free
PDF
Sung Jin Lee; Weiling He; Shaun B. Robinson; Michael R. Robinson; Karl G. Csaky; Hyuncheol Kim
Tags: conjunctiva, drug clearance, drug delivery systems, excretory function, eye
Investigative Ophthalmology & Visual Science October 2010, Vol.51, 5205-5212. doi:https://doi.org/10.1167/iovs.10-5337

Retina

Detection of Cystoid Macular Edema with Three-Dimensional Optical Coherence Tomography versus Fluorescein Angiography Free
PDF
Yanling Ouyang; Pearse A. Keane; Srinivas R. Sadda; Alexander C. Walsh
Tags: education, medical, continuing, eye, fluorescein angiography, macular edema, cystoid, optical coherence tomography
Investigative Ophthalmology & Visual Science October 2010, Vol.51, 5213-5218. doi:https://doi.org/10.1167/iovs.09-4635
Macular Pigment Optical Density in Central Serous Chorioretinopathy Free
PDF
Yuzuru Sasamoto; Fumi Gomi; Miki Sawa; Motokazu Tsujikawa; Toshimitsu Hamasaki
Tags: central serous chorioretinopathy, eye, optics, pigment, retina
Investigative Ophthalmology & Visual Science October 2010, Vol.51, 5219-5225. doi:https://doi.org/10.1167/iovs.09-4881
ERK1/2 Signaling Pathways Involved in VEGF Release in Diabetic Rat Retina Free
PDF
Xiaofeng Ye; Gezhi Xu; Qing Chang; Jiaweng Fan; Zhongcui Sun; Yaowu Qin; Alice C. Jiang
Tags: diabetes mellitus, retina, vascular endothelial growth factor a, transcription factor ap-1, signal transduction pathways
Investigative Ophthalmology & Visual Science October 2010, Vol.51, 5226-5233. doi:https://doi.org/10.1167/iovs.09-4899
High Subretinal Fluid Procoagulant Activity in Rhegmatogenous Retinal Detachment Free
PDF
Lukas J. A. G. Ricker; Raed Al Dieri; Gerold J. M. Beckers; Elisabeth Pels; Albert T. A. Liem; Fred Hendrikse; Aize Kijlstra; H. Coenraad Hemker; Ellen C. La Heij
Tags: plasma, radiation recall dermatitis, rhegmatogenous retinal detachment, thrombin, vitreous body
Investigative Ophthalmology & Visual Science October 2010, Vol.51, 5234-5239. doi:https://doi.org/10.1167/iovs.10-5354
Diabetic eNOS-Knockout Mice Develop Accelerated Retinopathy Free
PDF
Qiuhong Li; Amrisha Verma; Ping-yang Han; Takahiko Nakagawa; Richard J. Johnson; Maria B. Grant; Martha Campbell-Thompson; Yagna P. R. Jarajapu; Bo Lei; William W. Hauswirth
Tags: diabetes mellitus, mice, nitric oxide synthase, retinal diseases, blood capillaries
Investigative Ophthalmology & Visual Science October 2010, Vol.51, 5240-5246. doi:https://doi.org/10.1167/iovs.09-5147
The Effect of Bright Light on Lens Compensation in Chicks Free
PDF
Regan S. Ashby; Frank Schaeffel
Tags: lens (device), lens, crystalline, myopia, dopamine
Investigative Ophthalmology & Visual Science October 2010, Vol.51, 5247-5253. doi:https://doi.org/10.1167/iovs.09-4689
In Vivo Assessment of Retinal Vascular Wall Dimensions Free
PDF
M. Dominik Fischer; Gesine Huber; Yuxi Feng; Naoyuki Tanimoto; Regine Mühlfriedel; Susanne C. Beck; Eric Tröger; Christoph Kernstock; Markus N. Preising; Birgit Lorenz; Hans Peter Hammes; Mathias W. Seeliger
Tags: arteriole, blood vessel wall, diameter, electroretinography, histology
Investigative Ophthalmology & Visual Science October 2010, Vol.51, 5254-5259. doi:https://doi.org/10.1167/iovs.09-5139
Three-Dimensional 1060-nm OCT: Choroidal Thickness Maps in Normal Subjects and Improved Posterior Segment Visualization in Cataract Patients Free
PDF
Marieh Esmaeelpour; Boris Považay; Boris Hermann; Bernd Hofer; Vedran Kajic; Ketan Kapoor; Nik J. L. Sheen; Rachel V. North; Wolfgang Drexler
Tags: cataract, diagnostic imaging, eye, maps
Investigative Ophthalmology & Visual Science October 2010, Vol.51, 5260-5266. doi:https://doi.org/10.1167/iovs.10-5196
Loss of Tubedown Expression as a Contributing Factor in the Development of Age-Related Retinopathy Free
PDF
Robert L. Gendron; Nora V. Laver; William V. Good; Hans E. Grossniklaus; Ewa Miskiewicz; Maria A. Whelan; Jacqueline Walker; Hélène Paradis
Tags: aging, body tissue, choroid, endothelium, eye
Investigative Ophthalmology & Visual Science October 2010, Vol.51, 5267-5277. doi:https://doi.org/10.1167/iovs.09-4527
17-β Estradiol Protects ARPE-19 Cells from Oxidative Stress through Estrogen Receptor-β Free
PDF
Anand Giddabasappa; Matthew Bauler; Muralimohan Yepuru; Edward Chaum; James T. Dalton; Jeetendra Eswaraka
Tags: estradiol, estrogen, mitochondria, oxidative stress, western blotting
Investigative Ophthalmology & Visual Science October 2010, Vol.51, 5278-5287. doi:https://doi.org/10.1167/iovs.10-5316
Evaluation of AAV-Mediated Expression of Chop2-GFP in the Marmoset Retina Free
PDF
Elena Ivanova; Grace-Soon Hwang; Zhuo-Hua Pan; David Troilo
Tags: callithrix, neurons, retina, mass or substance concentration per volume
Investigative Ophthalmology & Visual Science October 2010, Vol.51, 5288-5296. doi:https://doi.org/10.1167/iovs.10-5389
Multifocal ERG Defects Associated with Insufficient Long-Term Glycemic Control in Adolescents with Type 1 Diabetes Free
PDF
Ekta Lakhani; Tom Wright; Mohamed Abdolell; Carol Westall
Tags: adolescent, diabetes mellitus, type 1, electroretinography, glycemic control, hemoglobin a, glycosylated
Investigative Ophthalmology & Visual Science October 2010, Vol.51, 5297-5303. doi:https://doi.org/10.1167/iovs.10-5200
Retinal Disease in Rpe65-Deficient Mice: Comparison to Human Leber Congenital Amaurosis Due to RPE65 Mutations Free
PDF
Rafael C. Caruso; Tomas S. Aleman; Artur V. Cideciyan; Alejandro J. Roman; Alexander Sumaroka; Cristina L. Mullins; Sanford L. Boye; William W. Hauswirth; Samuel G. Jacobson
Tags: mice, leber's amaurosis, retinal diseases, mutation, photoreceptors
Investigative Ophthalmology & Visual Science October 2010, Vol.51, 5304-5313. doi:https://doi.org/10.1167/iovs.10-5559

Retinal Cell Biology

Altered mTOR Signaling in Senescent Retinal Pigment Epithelium Free
PDF
Yan Chen; Jian Wang; Jiyang Cai; Paul Sternberg
Tags: mtor serine-threonine kinases, signal transduction, retinal pigment epithelium, aging, retinal pigment cell
Investigative Ophthalmology & Visual Science October 2010, Vol.51, 5314-5319. doi:https://doi.org/10.1167/iovs.10-5280
In Vivo and In Vitro Development of S- and M-Cones in Rat Retina Free
PDF
Blanca Arango-Gonzalez; Arnold Szabó; German Pinzon-Duarte; Ákos Lukáts; Elke Guenther; Konrad Kohler
Tags: opsin, retina, retinal cone
Investigative Ophthalmology & Visual Science October 2010, Vol.51, 5320-5327. doi:https://doi.org/10.1167/iovs.09-4741
Ectopic Mitf in the Embryonic Chick Retina by Co-transfection of β-Catenin and Otx2 Free
PDF
Peter D. Westenskow; Jon B. McKean; Fumi Kubo; Shinichi Nakagawa; Sabine Fuhrmann
Tags: mitf protein, retina, transfection, embryo
Investigative Ophthalmology & Visual Science October 2010, Vol.51, 5328-5335. doi:https://doi.org/10.1167/iovs.09-5015
Ectopic Mitf in the Embryonic Chick Retina by Co-transfection of β-Catenin and Otx2 Free
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Peter D. Westenskow; Jon B. McKean; Fumi Kubo; Shinichi Nakagawa; Sabine Fuhrmann
Investigative Ophthalmology & Visual Science October 2010, Vol.51, 5328-5335. doi:https://doi.org/10.1167/iovs.09-5015
Complement Component C5a Activates ICAM-1 Expression on Human Choroidal Endothelial Cells Free
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Jessica M. Skeie; John H. Fingert; Stephen R. Russell; Edwin M. Stone; Robert F. Mullins
Tags: c5a receptors, choroid, complement system proteins, endothelial cells, intercellular adhesion molecule 1
Investigative Ophthalmology & Visual Science October 2010, Vol.51, 5336-5342. doi:https://doi.org/10.1167/iovs.10-5322
Modulation of MCT3 Expression during Wound Healing of the Retinal Pigment Epithelium Free
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Shannon Gallagher-Colombo; Arvydas Maminishkis; Susan Tate; Gerald B. Grunwald; Nancy J. Philp
Tags: antibodies, choroid, eye, fluorescent antibody technique, retinal pigment cell
Investigative Ophthalmology & Visual Science October 2010, Vol.51, 5343-5350. doi:https://doi.org/10.1167/iovs.09-5028

Visual Neuroscience

Measurement of Evoked Potentials after Electrical Stimulation of the Human Optic Nerve Free
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Marten E. Brelén; Valerie Vince; Benoit Gérard; Claude Veraart; Jean Delbeke
Tags: electric stimulation, evoked potentials, optic nerve, voluntary workers, visual prosthesis
Investigative Ophthalmology & Visual Science October 2010, Vol.51, 5351-5355. doi:https://doi.org/10.1167/iovs.09-4346
Task-Dependent V1 Responses in Human Retinitis Pigmentosa Free
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Yoichiro Masuda; Hiroshi Horiguchi; Serge O. Dumoulin; Ayumu Furuta; Satoru Miyauchi; Satoshi Nakadomari; Brian A. Wandell
Tags: blood oxygen level dependent, primary visual cortex, retinitis pigmentosa, visual fields, functional magnetic resonance imaging
Investigative Ophthalmology & Visual Science October 2010, Vol.51, 5356-5364. doi:https://doi.org/10.1167/iovs.09-4775

Visual Psychophysics and Physiological Optics

qCSF in Clinical Application: Efficient Characterization and Classification of Contrast Sensitivity Functions in Amblyopia Free
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Fang Hou; Chang-Bing Huang; Luis Lesmes; Li-Xia Feng; Liming Tao; Yi-Feng Zhou; Zhong-Lin Lu
Tags: amblyopia, contrast sensitivity, precision
Investigative Ophthalmology & Visual Science October 2010, Vol.51, 5365-5377. doi:https://doi.org/10.1167/iovs.10-5468
Influence of Amplitude, Starting Point, and Age on First- and Second-Order Dynamics of Edinger-Westphal–Stimulated Accommodation in Rhesus Monkeys Free
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Martin Baumeister; Mark Wendt; Adrian Glasser
Tags: cercopithecidae, velocity, visual accommodation, macaca mulatta
Investigative Ophthalmology & Visual Science October 2010, Vol.51, 5378-5390. doi:https://doi.org/10.1167/iovs.10-5269

Clinical Trials

Quantitative Comparison of Drusen Segmented on SD-OCT versus Drusen Delineated on Color Fundus Photographs Free
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Nieraj Jain; Sina Farsiu; Aziz A. Khanifar; Srilaxmi Bearelly; R. Theodore Smith; Joseph A. Izatt; Cynthia A. Toth
Tags: drusen, color, fundus photography
Investigative Ophthalmology & Visual Science October 2010, Vol.51, 4875-4883. doi:https://doi.org/10.1167/iovs.09-4962

Perspective

AGEs and Diabetic Retinopathy Free
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Alan W. Stitt
Tags: age, diabetic retinopathy, rage, diabetes mellitus
Investigative Ophthalmology & Visual Science October 2010, Vol.51, 4867-4874. doi:https://doi.org/10.1167/iovs.10-5881
Copyright © 2025 Association for Research in Vision and Ophthalmology.
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