Volume 51 Issue 10 | IOVS

Anatomy and Pathology/Oncology

Whole-Genome Microarray Detects Deletions and Loss of Heterozygosity of Chromosome 3 Occurring Exclusively in Metastasizing Uveal Melanoma Free

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Sarah L. Lake; Sarah E. Coupland; Azzam F. G. Taktak; Bertil E. Damato

Tags: chromosomes, human, pair 3, genes, genome, intraocular melanoma, loss of heterozygosity

Investigative Ophthalmology & Visual Science October 2010, Vol.51, 4884-4891. doi:10.1167/iovs.09-5083

CT Based Three-Dimensional Measurement of Orbit and Eye Anthropometry Free

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Ashley A. Weaver; Kathryn L. Loftis; Josh C. Tan; Stefan M. Duma; Joel D. Stitzel

Tags: anthropometry, eye, orbit

Investigative Ophthalmology & Visual Science October 2010, Vol.51, 4892-4897. doi:10.1167/iovs.10-5503

Genetic Heterogeneity in Uveal Melanoma Assessed by Multiplex Ligation-Dependent Probe Amplification Free

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Justyna Dopierala; Bertil E. Damato; Sarah L. Lake; Azzam F. G. Taktak; Sarah E. Coupland

Tags: amplification, genetic heterogeneity, heterogeneity, intraocular melanoma, ligation

Investigative Ophthalmology & Visual Science October 2010, Vol.51, 4898-4905. doi:10.1167/iovs.09-5004

Biochemistry and Molecular Biology

Leber's Hereditary Optic Neuropathy Affects Only Female Matrilineal Relatives in Two Chinese Families Free

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Jia Qu; Ying Wang; Yi Tong; Xiangtian Zhou; Fuxin Zhao; Li Yang; Shoukang Zhang; Juanjuan Zhang; Constance E. West; Min-Xin Guan

Tags: chinese (other dialects), chinese people, family, genetic pedigree, optic atrophy, hereditary, leber

Investigative Ophthalmology & Visual Science October 2010, Vol.51, 4906-4912. doi:10.1167/iovs.09-5027

Retinal Pigment Epithelium Defects Accelerate Photoreceptor Degeneration in Cell Type–Specific Knockout Mouse Models of Choroideremia Free

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Tanya Tolmachova; Silene T. Wavre-Shapton; Alun R. Barnard; Robert E. MacLaren; Clare E. Futter; Miguel C. Seabra

Tags: choroideremia, mice, mice, knockout, photoreceptors, retinal pigment epithelium

Investigative Ophthalmology & Visual Science October 2010, Vol.51, 4913-4920. doi:10.1167/iovs.09-4892

Proteome Analysis of Human Aqueous Humor Free

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Uttio Roy Chowdhury; Benjamin J. Madden; Mary Christine Charlesworth; Michael P. Fautsch

Tags: aqueous humor, cytokine, proteins, proteome, growth factor

Investigative Ophthalmology & Visual Science October 2010, Vol.51, 4921-4931. doi:10.1167/iovs.10-5531

An Intergenic Region between the tagSNP rs3793917 and rs11200638 in the HTRA1 Gene Indicates Association with Age-Related Macular Degeneration Free

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Andrea J. Richardson; F. M. Amirul Islam; Khin Zaw Aung; Robyn H. Guymer; Paul N. Baird

Tags: age-related macular degeneration, htra1 gene, single nucleotide polymorphism, genes

Investigative Ophthalmology & Visual Science October 2010, Vol.51, 4932-4936. doi:10.1167/iovs.09-5114

Variations in NTF4, VAV2, and VAV3 Genes Are Not Involved with Primary Open-Angle and Primary Angle-Closure Glaucomas in an Indian Population Free

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Kollu N. Rao; Inderjeet Kaur; Rajul S. Parikh; Anil K. Mandal; Garudadri Chandrasekhar; Ravi Thomas; Subhabrata Chakrabarti

Tags: angle closure glaucoma, genes, ntf5 gene, open-angle glaucoma, screening

Investigative Ophthalmology & Visual Science October 2010, Vol.51, 4937-4941. doi:10.1167/iovs.10-5553

7-Ketocholesterol–Induced Inflammation: Involvement of Multiple Kinase Signaling Pathways via NFκB but Independently of Reactive Oxygen Species Formation Free

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Ignacio M. Larrayoz; Jiahn-Dar Huang; Jung Wha Lee; Iranzu Pascual; Ignacio R. Rodríguez

Tags: cytokine, inflammation, interleukin-6, interleukin-8, mitogen-activated protein kinases

Investigative Ophthalmology & Visual Science October 2010, Vol.51, 4942-4955. doi:10.1167/iovs.09-4854

Clinical and Epidemiologic Research

Infrared Fundus Autofluorescence and Central Serous Chorioretinopathy Free

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Tetsuju Sekiryu; Tomohiro Iida; Ichiro Maruko; Kuniharu Saito; Takeshi Kondo

Tags: central serous chorioretinopathy, eye, fundus autofluorescence imaging, melanins, diagnostic imaging

Investigative Ophthalmology & Visual Science October 2010, Vol.51, 4956-4962. doi:10.1167/iovs.09-5009

The Epidemiology and Socioeconomic Associations of Retinal Detachment in Scotland: A Two-Year Prospective Population-Based Study Free

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Danny Mitry; David G. Charteris; David Yorston; M. A. Rehman Siddiqui; Harry Campbell; Anna-Louise Murphy; Brian W. Fleck; Alan F. Wright; Jaswinder Singh; the Scottish RD Study Group

Tags: epidemiology, incidence, radiation recall dermatitis, retinal detachment, scotland

Investigative Ophthalmology & Visual Science October 2010, Vol.51, 4963-4968. doi:10.1167/iovs.10-5400

Population Density and Refractive Error among Chinese Children Free

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Mingzhi Zhang; Liping Li; Lizhen Chen; Jack Lee; Jiasi Wu; Amy Yang; Connie Chen; Daocheng Xu; Dennis S. C. Lam; Abhishek Sharma; Sian Griffiths; Yang Gao; Nathan Congdon

Tags: child, chinese (other dialects), chinese people, myopia, population density

Investigative Ophthalmology & Visual Science October 2010, Vol.51, 4969-4976. doi:10.1167/iovs.10-5424

Impact of Ethnicity on the Correlation of Retinal Parameters with Axial Length Free

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Yasser M. Tariq; Chameen Samarawickrama; Amy Pai; George Burlutsky; Paul Mitchell

Tags: ethnic group, retinal nerve fiber layer, child, whites, asian

Investigative Ophthalmology & Visual Science October 2010, Vol.51, 4977-4982. doi:10.1167/iovs.10-5226

New-Onset Maternal Gestational Hypertension and Risk of Retinopathy of Prematurity Free

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Mohamed A. Zayed; Abhineet Uppal; M. Elizabeth Hartnett

Tags: hypertension, pregnancy-induced, infant, mothers, retinopathy of prematurity, birth weight

Investigative Ophthalmology & Visual Science October 2010, Vol.51, 4983-4988. doi:10.1167/iovs.10-5283

Association of Matrix Metalloproteinase Gene Polymorphisms with Refractive Error in Amish and Ashkenazi Families Free

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Robert Wojciechowski; Joan E. Bailey-Wilson; Dwight Stambolian

Tags: family, genes, matrix metalloproteinases, polymorphism, refractive errors

Investigative Ophthalmology & Visual Science October 2010, Vol.51, 4989-4995. doi:10.1167/iovs.10-5474

Trichiasis Surgery in The Gambia: A 4-Year Prospective Study Free

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Saul N. Rajak; Pateh Makalo; Ansumana Sillah; Martin J. Holland; David C. W. Mabey; Robin L. Bailey; Matthew J. Burton

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