Select a back issue
Select a back issue
  • Alerts
    User Alerts
    You are adding an alert for:
    Investigative Ophthalmology & Visual Science
    You will receive an email whenever new content is published in the Investigative Ophthalmology & Visual Science. You can manage this and all other alerts in My Account
    The alert will be sent to:
    ×
    This feature is available to authenticated users only.
    Sign In or Create an Account ×

Anatomy and Pathology/Oncology

Sex, Eye Size, and the Rate of Myopic Eye Growth Due to Form Deprivation in Outbred White Leghorn Chickens Free
PDF
Yen-Po Chen; Ankush Prashar; Paul M. Hocking; Jonathan T. Erichsen; Chi Ho To; Frank Schaeffel; Jeremy A. Guggenheim
Tags: chickens, disease susceptibility, eye, myopia
Investigative Ophthalmology & Visual Science February 2010, Vol.51, 651-657. doi:https://doi.org/10.1167/iovs.09-3826
Intravascular Presence of Tumor Cells as Prognostic Parameter in Uveal Melanoma: A 35-Year Survey Free
PDF
Long V. Ly; Omar F. F. Odish; Didi de Wolff-Rouendaal; Guy S. O. A. Missotten; Gregorius P. M. Luyten; Martine J. Jager
Tags: tumor cells, uveal melanoma, neoplasms, surveys
Investigative Ophthalmology & Visual Science February 2010, Vol.51, 658-665. doi:https://doi.org/10.1167/iovs.09-3824
Cross-sectional Anatomic Configurations of Peripapillary Atrophy Evaluated with Spectral Domain-Optical Coherence Tomography Free
PDF
Kelvin Yoon Chiang Lee; Atsuo Tomidokoro; Rei Sakata; Shinsuke Konno; Chihiro Mayama; Hitomi Saito; Keiko Hayashi; Aiko Iwase; Makoto Araie
Tags: atrophy, eye, optic disk, optics, tomography
Investigative Ophthalmology & Visual Science February 2010, Vol.51, 666-671. doi:https://doi.org/10.1167/iovs.09-3663

Biochemistry and Molecular Biology

Formation of Amyloid Fibrils In Vitro from Partially Unfolded Intermediates of Human γC-Crystallin Free
PDF
Yongting Wang; Sarah Petty; Amy Trojanowski; Kelly Knee; Daniel Goulet; Ishita Mukerji; Jonathan King
Tags: amyloid fibrils, crystallins, fibril, proteins, fluorescence
Investigative Ophthalmology & Visual Science February 2010, Vol.51, 672-678. doi:https://doi.org/10.1167/iovs.09-3987
Trichostatin A–Induced TGF-β Type II Receptor Expression in Retinoblastoma Cell Lines Free
PDF
Yoshiko Kashiwagi; Kuniko Horie; Chikako Kanno; Motoko Inomata; Takashi Imamura; Mitsuyasu Kato; Teiko Yamamoto; Hidetoshi Yamashita
Tags: cell lines, retinoblastoma
Investigative Ophthalmology & Visual Science February 2010, Vol.51, 679-685. doi:https://doi.org/10.1167/iovs.09-4073
Functional Redundancy of R7 RGS Proteins in ON-Bipolar Cell Dendrites Free
PDF
Frank S. Chen; Hoon Shim; Duncan Morhardt; Rebecca Dallman; Elizabeth Krahn; Ludine McWhinney; Anjali Rao; Stephen J. Gold; Ching-Kang Chen
Tags: dendrites, electroretinography, mice, redundancy, retina
Investigative Ophthalmology & Visual Science February 2010, Vol.51, 686-693. doi:https://doi.org/10.1167/iovs.09-4084

Clinical and Epidemiologic Research

Activities of Daily Vision Scale: What Do the Subscales Measure? Free
PDF
Vijaya K. Gothwal; Thomas A. Wright; Ecosse L. Lamoureux; Konrad Pesudovs
Tags: cataract, myopia, vision, rasch model, disability
Investigative Ophthalmology & Visual Science February 2010, Vol.51, 694-700. doi:https://doi.org/10.1167/iovs.09-3448
Prevalence of Early and Late Age-Related Macular Degeneration in India: The INDEYE Study Free
PDF
Tiruvengada Krishnan; Ravilla D. Ravindran; Gudlavalleti V. S. Murthy; Praveen Vashist; Kathryn E. Fitzpatrick; R. Duraisami Thulasiraj; Neena John; Giovanni Maraini; Monica Camparini; Usha Chakravarthy; Astrid E. Fletcher
Tags: age-related macular degeneration, india, prevalence
Investigative Ophthalmology & Visual Science February 2010, Vol.51, 701-707. doi:https://doi.org/10.1167/iovs.09-4114
Ophthalmic Artery Blood Flow in Very-Low-Birth-Weight Preterm Infants Free
PDF
Catia Rejane S. Soares; Rita C. Silveira; Renato S. Procianoy
Tags: infant, premature, infant, very low birth weight, newborn, ophthalmic artery, vascular flow
Investigative Ophthalmology & Visual Science February 2010, Vol.51, 708-711. doi:https://doi.org/10.1167/iovs.09-4206
Reliability and Validity of the National Eye Institute Visual Function Questionnaire-25 in Patients with Age-Related Macular Degeneration Free
PDF
Dennis A. Revicki; Anne M. Rentz; Neesha Harnam; Vince S. Thomas; Paolo Lanzetta
Tags: age-related macular degeneration, eye, questionnaires, reliability, validity of results
Investigative Ophthalmology & Visual Science February 2010, Vol.51, 712-717. doi:https://doi.org/10.1167/iovs.09-3766
Adaptive Gait Changes Due to Spectacle Magnification and Dioptric Blur in Older People Free
PDF
David B. Elliott; Graham J. Chapman
Tags: gait, magnification, older adult, lens (device), lens, crystalline
Investigative Ophthalmology & Visual Science February 2010, Vol.51, 718-722. doi:https://doi.org/10.1167/iovs.09-4250
Parameters Associated with the Different Astigmatism Axis Orientations Free
PDF
Yossi Mandel; Richard A. Stone; David Zadok
Tags: astigmatism, body mass index procedure
Investigative Ophthalmology & Visual Science February 2010, Vol.51, 723-730. doi:https://doi.org/10.1167/iovs.09-4356
Susceptibility Genes and Progression in Age-Related Maculopathy: A Study of Single Eyes Free
PDF
Astrid Farwick; Jürgen Wellmann; Monika Stoll; Daniel Pauleikhoff; Hans-Werner Hense
Tags: age-related macular degeneration, disease susceptibility, eye, genes, motor agitation and retardation scale
Investigative Ophthalmology & Visual Science February 2010, Vol.51, 731-736. doi:https://doi.org/10.1167/iovs.09-3953
Heritabilities of Ocular Biometrical Traits in Two Croatian Isolates with Extended Pedigrees Free
PDF
Veronique Vitart; Goran Benčić; Caroline Hayward; Jelena Škunca Herman; Jennifer Huffman; Susan Campbell; Kajo Bućan; Lina Zgaga; Ivana Kolčić; Ozren Polašek; Harry Campbell; Alan Wright; Zoran Vatavuk; Igor Rudan
Tags: chief complaint, croatian, genetic pedigree, refraction, vaccine information sheets
Investigative Ophthalmology & Visual Science February 2010, Vol.51, 737-743. doi:https://doi.org/10.1167/iovs.09-3720
Vision-Related Quality of Life and Visual Function after Vitrectomy for Various Vitreoretinal Disorders Free
PDF
Fumiki Okamoto; Yoshifumi Okamoto; Shinichi Fukuda; Takahiro Hiraoka; Tetsuro Oshika
Tags: quality of life, vision, vitrectomy, vitreoretinal disease, preoperative care
Investigative Ophthalmology & Visual Science February 2010, Vol.51, 744-751. doi:https://doi.org/10.1167/iovs.09-3992
Objective Measurement of Distance Visual Acuity Determined by Computerized Optokinetic Nystagmus Test Free
PDF
Joon Young Hyon; Hwan Eok Yeo; Jong-Mo Seo; In Bum Lee; Jin Hak Lee; Jeong-Min Hwang
Tags: visual acuity, nystagmus, optokinetic
Investigative Ophthalmology & Visual Science February 2010, Vol.51, 752-757. doi:https://doi.org/10.1167/iovs.09-4362

Cornea

Cultivated Human Conjunctival Epithelial Transplantation for Total Limbal Stem Cell Deficiency Free
PDF
Leonard P. K. Ang; Hidetoshi Tanioka; Satoshi Kawasaki; Leslie P. S. Ang; Kenta Yamasaki; Tien Phuc Do; Zaw M. Thein; Noriko Koizumi; Takahiro Nakamura; Norihiko Yokoi; Aoi Komuro; Tsutomu Inatomi; Mina Nakatsukasa; Shigeru Kinoshita
Tags: conjunctiva, cornea, epithelium, limbal stem cell deficiency, transplantation
Investigative Ophthalmology & Visual Science February 2010, Vol.51, 758-764. doi:https://doi.org/10.1167/iovs.09-3379
Preservation of the Limbal Stem Cell Phenotype by Appropriate Culture Techniques Free
PDF
Ewa Anna Meyer-Blazejewska; Friedrich E. Kruse; Katrin Bitterer; Christian Meyer; Carmen Hofmann-Rummelt; Peter H. Wünsch; Ursula Schlötzer-Schrehardt
Tags: culture media, dissociation, fibrin, phenotype, stem cells
Investigative Ophthalmology & Visual Science February 2010, Vol.51, 765-774. doi:https://doi.org/10.1167/iovs.09-4109
Comparison of Fresh Corneal Tissue versus Glycerin-Cryopreserved Corneal Tissue in Deep Anterior Lamellar Keratoplasty Free
PDF
Wei Chen; Ying Lin; Xiaobo Zhang; Lihua Wang; Mimi Liu; Jingbo Liu; Ya Ye; Li Sun; Huixiang Ma; Jia Qu
Tags: body tissue, cornea, cryopreservation, glycerol, keratoplasty
Investigative Ophthalmology & Visual Science February 2010, Vol.51, 775-781. doi:https://doi.org/10.1167/iovs.09-3422
Developmental Corneal Innervation: Interactions between Nerves and Specialized Apical Corneal Epithelial Cells Free
PDF
James K. Kubilus; Thomas F. Linsenmayer
Tags: cornea, corneal epithelial cells, nerve supply, neurons, nervousness
Investigative Ophthalmology & Visual Science February 2010, Vol.51, 782-789. doi:https://doi.org/10.1167/iovs.09-3942
Impaired Angiogenic Response in the Corneas of Mice Lacking Osteopontin Free
PDF
Norihito Fujita; Shuko Fujita; Yuka Okada; Kyoko Fujita; Ai Kitano; Osamu Yamanaka; Takeshi Miyamoto; Shigeyuki Kon; Toshimitsu Uede; Susan R. Rittling; David T. Denhardt; Shizuya Saika
Tags: angiogenesis, cornea, cytokine, fibroblasts, mice
Investigative Ophthalmology & Visual Science February 2010, Vol.51, 790-794. doi:https://doi.org/10.1167/iovs.09-3420
Essential Role for Pbx1 in Corneal Morphogenesis Free
PDF
Mark J. Murphy; Bozena K. Polok; Daniel F. Schorderet; Michael L. Cleary
Tags: cornea, mice, morphogenesis, corneal epithelium
Investigative Ophthalmology & Visual Science February 2010, Vol.51, 795-803. doi:https://doi.org/10.1167/iovs.08-3327
Neuroprotectin D1 Synthesis and Corneal Nerve Regeneration after Experimental Surgery and Treatment with PEDF plus DHA Free
PDF
M. Soledad Cortina; Jiucheng He; Na Li; Nicolas G. Bazan; Haydee E. P. Bazan
Tags: cornea, nerve regeneration, neurons, surgical procedures, operative, epithelium
Investigative Ophthalmology & Visual Science February 2010, Vol.51, 804-810. doi:https://doi.org/10.1167/iovs.09-3641
Model to Predict Endothelial Cell Loss after Iris-Fixated Phakic Intraocular Lens Implantation Free
PDF
Muriël Doors; Tos T. J. M. Berendschot; Carroll A. B. Webers; Rudy M. M. A. Nuijts
Tags: endothelial cells, implantation procedure, intraocular lens implantation procedure, iris fixation, preoperative care
Investigative Ophthalmology & Visual Science February 2010, Vol.51, 811-815. doi:https://doi.org/10.1167/iovs.09-3981
Role of CCR7 in Facilitating Direct Allosensitization and Regulatory T-Cell Function in High-Risk Corneal Transplantation Free
PDF
Yiping Jin; Sunil K. Chauhan; Daniel R. Saban; Reza Dana
Tags: donors, keratoplasty, t-lymphocytes, regulatory t-lymphocytes, lesch-nyhan syndrome
Investigative Ophthalmology & Visual Science February 2010, Vol.51, 816-821. doi:https://doi.org/10.1167/iovs.09-3952
Induction of FGF-2 Synthesis by IL-1β in Aqueous Humor through P13-Kinase and p38 in Rabbit Corneal Endothelium Free
PDF
Jong-Suk Song; Jeong Goo Lee; EunDuck P. Kay
Tags: aqueous humor, corneal endothelium, fibroblast growth factor 2, freezing, oryctolagus cuniculus
Investigative Ophthalmology & Visual Science February 2010, Vol.51, 822-829. doi:https://doi.org/10.1167/iovs.09-4240
Cellular-Level Characterization of Lymph Vessels in Live, Unlabeled Corneas by In Vivo Confocal Microscopy Free
PDF
Beatrice Bourghardt Peebo; Per Fagerholm; Catharina Traneus-Röckert; Neil Lagali
Tags: cornea, lymph, microscopy, confocal, lymphatic vessels
Investigative Ophthalmology & Visual Science February 2010, Vol.51, 830-835. doi:https://doi.org/10.1167/iovs.09-4407
Aliphatic β-Nitroalcohols for Therapeutic Corneoscleral Cross-linking: Chemical Mechanisms and Higher Order Nitroalcohols Free
PDF
David C. Paik; Marissa R. Solomon; Quan Wen; Nicholas J. Turro; Stephen L. Trokel
Tags: body temperature, cross-linking, formaldehyde, nitrites, temperature
Investigative Ophthalmology & Visual Science February 2010, Vol.51, 836-843. doi:https://doi.org/10.1167/iovs.09-3937
Association between High Tear Epidermal Growth Factor Levels and Corneal Subepithelial Fibrosis in Dry Eye Conditions Free
PDF
Kavita Rao; William J. Farley; Stephen C. Pflugfelder
Tags: cornea, dry eye syndromes, epidermal growth factor, fibrosis, metaplasia
Investigative Ophthalmology & Visual Science February 2010, Vol.51, 844-849. doi:https://doi.org/10.1167/iovs.09-3875
Potentiation of Femtosecond Laser Intratissue Refractive Index Shaping (IRIS) in the Living Cornea with Sodium Fluorescein Free
PDF
Lana J. Nagy; Li Ding; Lisen Xu; Wayne H. Knox; Krystel R. Huxlin
Tags: cornea, femtosecond pulsed lasers, body tissue, sodium fluorescein, refractive index
Investigative Ophthalmology & Visual Science February 2010, Vol.51, 850-856. doi:https://doi.org/10.1167/iovs.09-3901
Optical Functional Properties of the Boston Keratoprosthesis Free
PDF
Rony R. Sayegh; Linda Avena Diaz; Fernando Vargas-Martín; Robert H. Webb; Claes H. Dohlman; Eli Peli
Tags: contact lenses, eye, glare, immune reconstitution inflammatory syndrome, optics
Investigative Ophthalmology & Visual Science February 2010, Vol.51, 857-863. doi:https://doi.org/10.1167/iovs.09-3372
Growth Factor Regulation of Corneal Keratocyte Differentiation and Migration in Compressed Collagen Matrices Free
PDF
Areum Kim; Neema Lakshman; Dimitris Karamichos; W. Matthew Petroll
Tags: collagen, cornea, growth factor, keratocytes, platelet-derived growth factor
Investigative Ophthalmology & Visual Science February 2010, Vol.51, 864-875. doi:https://doi.org/10.1167/iovs.09-4200
Human Corneal Adaptation to Mechanical, Cooling, and Chemical Stimuli Free
PDF
Jiangtao Chen; Yunwei Feng; Trefford L. Simpson
Tags: cornea
Investigative Ophthalmology & Visual Science February 2010, Vol.51, 876-881. doi:https://doi.org/10.1167/iovs.08-3072

Glaucoma

Twenty-four Hour (Nyctohemeral) Rhythm of Intraocular Pressure and Ocular Perfusion Pressure in Normal-Tension Glaucoma Free
PDF
Elisabeth Renard; Karine Palombi; Claude Gronfier; Jean-Louis Pepin; Christian Noel; Christophe Chiquet; Jean-Paul Romanet
Tags: intraocular pressure, low tension glaucoma, perfusion, rhythm, night time
Investigative Ophthalmology & Visual Science February 2010, Vol.51, 882-889. doi:https://doi.org/10.1167/iovs.09-3668
Violation of the ISNT Rule in Nonglaucomatous Pediatric Optic Disc Cupping Free
PDF
Alexander E. Pogrebniak; Ben Wehrung; Katherine L. Pogrebniak; Rajesh K. Shetty; Pam Crawford
Tags: cupping therapy, eye, optic disk, pediatrics
Investigative Ophthalmology & Visual Science February 2010, Vol.51, 890-895. doi:https://doi.org/10.1167/iovs.09-3837
Retinal Nerve Fiber Layer Thickness Measurement Comparability between Time Domain Optical Coherence Tomography (OCT) and Spectral Domain OCT Free
PDF
Jong S. Kim; Hiroshi Ishikawa; Michelle L. Gabriele; Gadi Wollstein; Richard A. Bilonick; Larry Kagemann; James G. Fujimoto; Joel S. Schuman
Tags: optical coherence tomography, retinal nerve fiber layer, glaucoma
Investigative Ophthalmology & Visual Science February 2010, Vol.51, 896-902. doi:https://doi.org/10.1167/iovs.09-4110
Tumor Necrosis Factor-α Concentrations in the Aqueous Humor of Patients with Glaucoma Free
PDF
Hideko Sawada; Takeo Fukuchi; Takayuki Tanaka; Haruki Abe
Tags: aqueous humor, glaucoma, tumor necrosis, tumor necrosis factors
Investigative Ophthalmology & Visual Science February 2010, Vol.51, 903-906. doi:https://doi.org/10.1167/iovs.09-4247
Hemoglobin Expression and Regulation in Glaucoma: Insights into Retinal Ganglion Cell Oxygenation Free
PDF
Gülgün Tezel; Xiangjun Yang; Cheng Luo; Jian Cai; Angela D. Kain; David W. Powell; Markus H. Kuehn; William M. Pierce
Tags: eye, glaucoma, hemoglobin, hypoxia, proteins
Investigative Ophthalmology & Visual Science February 2010, Vol.51, 907-919. doi:https://doi.org/10.1167/iovs.09-4014
Impairments of Contrast Discrimination and Contrast Adaptation in Glaucoma Free
PDF
Allison M. McKendrick; Geoff P. Sampson; Mark J. Walland; David R. Badcock
Tags: glaucoma
Investigative Ophthalmology & Visual Science February 2010, Vol.51, 920-927. doi:https://doi.org/10.1167/iovs.08-3332
Combined Treatment with Bevacizumab and 5-Fluorouracil Attenuates the Postoperative Scarring Response after Experimental Glaucoma Filtration Surgery Free
PDF
Alicia How; Jocelyn Leng Leng Chua; Amanda Charlton; Roseline Su; Marcus Lim; Rajesh S. Kumar; Jonathan G. Crowston; Tina T. Wong
Tags: bevacizumab, blister, cicatrix, combined modality therapy, filtering surgery
Investigative Ophthalmology & Visual Science February 2010, Vol.51, 928-932. doi:https://doi.org/10.1167/iovs.09-3949
Increased 24-Hour Variation of Human Intraocular Pressure with Short Axial Length Free
PDF
Nils A. Loewen; John H. K. Liu; Robert N. Weinreb
Tags: intraocular pressure, myopia, hyperopia, emmetropia, supine position
Investigative Ophthalmology & Visual Science February 2010, Vol.51, 933-937. doi:https://doi.org/10.1167/iovs.09-4218
Comparison of Cirrus OCT and Stratus OCT on the Ability to Detect Localized Retinal Nerve Fiber Layer Defects in Preperimetric Glaucoma Free
PDF
Jin Wook Jeoung; Ki Ho Park
Tags: glaucoma, retinal nerve fiber layer
Investigative Ophthalmology & Visual Science February 2010, Vol.51, 938-945. doi:https://doi.org/10.1167/iovs.08-3335
Experimental Model of Ocular Hypertension in the Rat: Study of the Optic Nerve Capillaries and Action of Hypotensive Drugs Free
PDF
Florentina Díaz; Alicia Villena; Lourdes Vidal; Mercedes Moreno; José García-Campos; Ignacio Pérez de Vargas
Tags: antihypertensive agents, blood capillaries, capillary bed, optic nerve, ocular hypertension
Investigative Ophthalmology & Visual Science February 2010, Vol.51, 946-951. doi:https://doi.org/10.1167/iovs.09-3667
Elevated Albumin in Retinas of Monkeys with Experimental Glaucoma Free
PDF
Louvenia Carter-Dawson; Yujin Zhang; Ronald S. Harwerth; Ricky Rojas; Pramod Dash; Xinping C. Zhao; Elizabeth WoldeMussie; Guadalupe Ruiz; Alice Chuang; William P. Dubinsky; John B. Redell
Tags: albumins, cercopithecidae, glaucoma, proteins, retina
Investigative Ophthalmology & Visual Science February 2010, Vol.51, 952-959. doi:https://doi.org/10.1167/iovs.09-4331
Identification of Barriers to Retinal Engraftment of Transplanted Stem Cells Free
PDF
Thomas V. Johnson; Natalie D. Bull; Keith R. Martin
Tags: engraftment, retina, stem cells, tissue transplants, laminin
Investigative Ophthalmology & Visual Science February 2010, Vol.51, 960-970. doi:https://doi.org/10.1167/iovs.09-3884
Endothelial Nitric Oxide Synthase Gene Variants and Primary Open-Angle Glaucoma: Interactions with Sex and Postmenopausal Hormone Use Free
PDF
Jae Hee Kang; Janey L. Wiggs; Bernard A. Rosner; Susan E. Hankinson; Wael Abdrabou; Bao Jian Fan; Jonathan Haines; Louis R. Pasquale
Tags: genes, hormones, nitric oxide synthase, open-angle glaucoma, postmenopause
Investigative Ophthalmology & Visual Science February 2010, Vol.51, 971-979. doi:https://doi.org/10.1167/iovs.09-4266
Laser-Induced Ocular Hypertension in Albino CD-1 Mice Free
PDF
Christine T. Fu; David Sretavan
Tags: albinism, axon, intraocular pressure, laser therapy, lasers
Investigative Ophthalmology & Visual Science February 2010, Vol.51, 980-990. doi:https://doi.org/10.1167/iovs.09-4324
Axonal/Glial Upregulation of EphB/ephrin-B Signaling in Mouse Experimental Ocular Hypertension Free
PDF
Christine T. Fu; Tony Tran; David Sretavan
Tags: ephrins, signal transduction, up-regulation (physiology), optic disk, mice
Investigative Ophthalmology & Visual Science February 2010, Vol.51, 991-1001. doi:https://doi.org/10.1167/iovs.09-3579

Immunology and Microbiology

Platelet-Derived Growth Factor-BB: A Stimulus for Cytokine Production by Orbital Fibroblasts in Graves' Ophthalmopathy Free
PDF
Leendert van Steensel; Dion Paridaens; Gemma M. Dingjan; Paul L. A. van Daele; P. Martin van Hagen; Robert W. A. M. Kuijpers; Willem A. van den Bosch; Hemmo A. Drexhage; Herbert Hooijkaas; Willem A. Dik
Tags: cytokine, fibroblasts, platelet-derived growth factor, graves' ophthalmopathy
Investigative Ophthalmology & Visual Science February 2010, Vol.51, 1002-1007. doi:https://doi.org/10.1167/iovs.09-4338
Live Conjunctiva-Associated Lymphoid Tissue Analysis in Rabbit under Inflammatory Stimuli Using In Vivo Confocal Microscopy Free
PDF
Hong Liang; Christophe Baudouin; Benedicte Dupas; Françoise Brignole-Baudouin
Tags: conjunctiva, lymphoid tissue, microscopy, confocal, oryctolagus cuniculus, tumor necrosis factors
Investigative Ophthalmology & Visual Science February 2010, Vol.51, 1008-1015. doi:https://doi.org/10.1167/iovs.09-3509

Physiology and Pharmacology

Effect of HCN Channel Inhibition on Retinal Morphology and Function in Normal and Dystrophic Rodents Free
PDF
Luca Della Santina; Muriel Bouly; Antonella Asta; Gian Carlo Demontis; Luigi Cervetto; Claudia Gargini
Tags: electroretinography, ivabradine, language morphology, mice, morphology
Investigative Ophthalmology & Visual Science February 2010, Vol.51, 1016-1023. doi:https://doi.org/10.1167/iovs.09-3680
Permeability of Human Amniotic Membrane to Ofloxacin In Vitro Free
PDF
Miklós D. Resch; Béla E. Resch; Eszter Csizmazia; László Imre; János Németh; Piroska Révész; Erzsébet Csányi
Tags: amnion, ofloxacin, permeability
Investigative Ophthalmology & Visual Science February 2010, Vol.51, 1024-1027. doi:https://doi.org/10.1167/iovs.09-4254
Assessment of the Integrin α5β1 Antagonist JSM6427 in Proliferative Vitreoretinopathy Using In Vitro Assays and a Rabbit Model of Retinal Detachment Free
PDF
Grit Zahn; Kristine Volk; Geoffrey P. Lewis; Dörte Vossmeyer; Roland Stragies; Jeffrey S. Heier; Paul E. Daniel, Jr; Anthony P. Adamis; Ethan A. Chapin; Steven K. Fisher; Frank G. Holz; Karin U. Löffler; Jochen Knolle
Tags: integrins, oryctolagus cuniculus, retinal detachment, vitreoretinopathy, proliferative, antagonists
Investigative Ophthalmology & Visual Science February 2010, Vol.51, 1028-1035. doi:https://doi.org/10.1167/iovs.09-3575

Retina

Mutations in ASCC3L1 on 2q11.2 Are Associated with Autosomal Dominant Retinitis Pigmentosa in a Chinese Family Free
PDF
Ningdong Li; Han Mei; Ian M. MacDonald; XiaoDong Jiao; J. Fielding Hejtmancik
Tags: chinese (other dialects), chinese people, family, mutation, retinitis pigmentosa
Investigative Ophthalmology & Visual Science February 2010, Vol.51, 1036-1043. doi:https://doi.org/10.1167/iovs.09-3725
Inhibition of Vitreoretinal VEGF Elevation and Blood–Retinal Barrier Breakdown in Streptozotocin-Induced Diabetic Rats by Brimonidine Free
PDF
Jyotirmoy Kusari; Sheila X. Zhou; Edwin Padillo; Kenneth G. Clarke; Daniel W. Gil
Tags: diabetes mellitus, rats, streptozocin, vascular endothelial growth factor a, proteins
Investigative Ophthalmology & Visual Science February 2010, Vol.51, 1044-1051. doi:https://doi.org/10.1167/iovs.08-3293
RNA Binding Protein with Multiple Splicing: A New Marker for Retinal Ganglion Cells Free
PDF
Jacky M. K. Kwong; Joseph Caprioli; Natik Piri
Tags: immunohistochemistry, retina, retinal ganglion cells, rna splicing, rna, messenger
Investigative Ophthalmology & Visual Science February 2010, Vol.51, 1052-1058. doi:https://doi.org/10.1167/iovs.09-4098
Severe Retinal Degeneration Caused by a Novel Rhodopsin Mutation Free
PDF
Haiquan Liu; Meng Wang; Chun-Hong Xia; Xin Du; John G. Flannery; Kevin D. Ridge; Bruce Beutler; Xiaohua Gong
Tags: mice, mutation, retinal degeneration, rhodopsin, mutant proteins
Investigative Ophthalmology & Visual Science February 2010, Vol.51, 1059-1065. doi:https://doi.org/10.1167/iovs.09-3585
Fourier Domain Optical Coherence Tomography as a Noninvasive Means for In Vivo Detection of Retinal Degeneration in Xenopus laevis Tadpoles Free
PDF
Damian C. Lee; Jing Xu; Marinko V. Sarunic; Orson L. Moritz
Tags: optical coherence tomography, retinal degeneration, xenopus laevis, diagnostic imaging, animals, transgenic
Investigative Ophthalmology & Visual Science February 2010, Vol.51, 1066-1070. doi:https://doi.org/10.1167/iovs.09-4260
Impact of Scanning Density on Measurements from Spectral Domain Optical Coherence Tomography Free
PDF
Srinivas R. Sadda; Pearse A. Keane; Yanling Ouyang; Jared F. Updike; Alexander C. Walsh
Tags: maps, optical coherence tomography, volume
Investigative Ophthalmology & Visual Science February 2010, Vol.51, 1071-1078. doi:https://doi.org/10.1167/iovs.09-4325
Normal Central Retinal Function and Structure Preserved in Retinitis Pigmentosa Free
PDF
Samuel G. Jacobson; Alejandro J. Roman; Tomas S. Aleman; Alexander Sumaroka; Waldo Herrera; Elizabeth A. M. Windsor; Lori A. Atkinson; Sharon B. Schwartz; Janet D. Steinberg; Artur V. Cideciyan
Tags: photoreceptors, retina, retinal cone, retinitis pigmentosa, rod photoreceptors
Investigative Ophthalmology & Visual Science February 2010, Vol.51, 1079-1085. doi:https://doi.org/10.1167/iovs.09-4372
The Relationship of Macular Pigment Optical Density to Serum Lutein in Retinitis Pigmentosa Free
PDF
Michael A. Sandberg; Elizabeth J. Johnson; Eliot L. Berson
Tags: lutein, optics, pigment, retinitis pigmentosa
Investigative Ophthalmology & Visual Science February 2010, Vol.51, 1086-1091. doi:https://doi.org/10.1167/iovs.09-3396
Alterations in Serum Fatty Acid Concentrations and Desaturase Activities in Bietti Crystalline Dystrophy Unaffected by CYP4V2 Genotypes Free
PDF
Timothy Y. Y. Lai; Kai-On Chu; Kwok-Ping Chan; Tsz-Kin Ng; Gary H. F. Yam; Dennis S. C. Lam; Chi-Pui Pang
Tags: fatty acids, genotype, crystal structure, insulin
Investigative Ophthalmology & Visual Science February 2010, Vol.51, 1092-1097. doi:https://doi.org/10.1167/iovs.09-3665
Identification of Genes and Pathways Involved in Retinal Neovascularization by Microarray Analysis of Two Animal Models of Retinal Angiogenesis Free
PDF
Franco M. Recchia; Lili Xu; John S. Penn; Braden Boone; Phillip J. Dexheimer
Tags: angiogenesis, animal model, gene expression, genes, retinal neovascularization
Investigative Ophthalmology & Visual Science February 2010, Vol.51, 1098-1105. doi:https://doi.org/10.1167/iovs.09-4006
Cone versus Rod Disease in a Mutant Rpgr Mouse Caused by Different Genetic Backgrounds Free
PDF
Sandra Brunner; Sergej Skosyrski; Renate Kirschner-Schwabe; Klaus-Peter Knobeloch; John Neidhardt; Silke Feil; Esther Glaus; Ulrich F. O. Luhmann; Klaus Rüther; Wolfgang Berger
Tags: genetics, mice, retinal cone, rod photoreceptors, mutation
Investigative Ophthalmology & Visual Science February 2010, Vol.51, 1106-1115. doi:https://doi.org/10.1167/iovs.08-2742
Noncoding Variant in the Complement Factor H Gene and Risk of Exudative Age-Related Macular Degeneration in a Chinese Population Free
PDF
Lei Cui; Haiying Zhou; Jie Yu; Erdan Sun; Yinbo Zhang; Wei Jia; Yiqun Jiao; Torkel Snellingen; Xipu Liu; Apiradee Lim; Ningli Wang; Ningpu Liu
Tags: chinese (other dialects), chinese people, complement factor h, exudative age-related macular degeneration, genes
Investigative Ophthalmology & Visual Science February 2010, Vol.51, 1116-1120. doi:https://doi.org/10.1167/iovs.09-4265

Retinal Cell Biology

RGS7 and -11 Complexes Accelerate the ON-Bipolar Cell Light Response Free
PDF
Jianmei Zhang; Brett G. Jeffrey; Catherine W. Morgans; Neal S. Burke; Tammie L. Haley; Robert M. Duvoisin; R. Lane Brown
Tags: complex, electroretinography, mice, rod photoreceptors, proteins
Investigative Ophthalmology & Visual Science February 2010, Vol.51, 1121-1129. doi:https://doi.org/10.1167/iovs.09-4163
Function of MYO7A in the Human RPE and the Validity of Shaker1 Mice as a Model for Usher Syndrome 1B Free
PDF
Daniel Gibbs; Tanja Diemer; Kornnika Khanobdee; Jane Hu; Dean Bok; David S. Williams
Tags: cell motility, melanosomes, mice, retinal pigment cell, usher syndrome
Investigative Ophthalmology & Visual Science February 2010, Vol.51, 1130-1135. doi:https://doi.org/10.1167/iovs.09-4032
Role of Cytosolic Phospholipase A2 in Retinal Neovascularization Free
PDF
Joshua M. Barnett; Gary W. McCollum; John S. Penn
Tags: cobra perilaryngeal airway, phospholipases a, retinal neovascularization, vascular endothelial growth factor a, cytosol
Investigative Ophthalmology & Visual Science February 2010, Vol.51, 1136-1142. doi:https://doi.org/10.1167/iovs.09-3691
Silencing of the CHM Gene Alters Phagocytic and Secretory Pathways in the Retinal Pigment Epithelium Free
PDF
Nataliya V. Gordiyenko; Robert N. Fariss; Connie Zhi; Ian M. MacDonald
Tags: bodily secretions, catabolism, genes, phagocytosis, phagosomes
Investigative Ophthalmology & Visual Science February 2010, Vol.51, 1143-1150. doi:https://doi.org/10.1167/iovs.09-4117
Microarray Analysis Identifies Changes in Inflammatory Gene Expression in Response to Amyloid-β Stimulation of Cultured Human Retinal Pigment Epithelial Cells Free
PDF
Khaliq H. Kurji; Jing Z. Cui; Tony Lin; David Harriman; Shiv S. Prasad; Ljuba Kojic; Joanne A. Matsubara
Tags: amyloid, gene expression, genes, retinal pigment cell, interleukin-8
Investigative Ophthalmology & Visual Science February 2010, Vol.51, 1151-1163. doi:https://doi.org/10.1167/iovs.09-3622
Mitochondrial DNA Damage Induced by 7-Ketocholesterol in Human Retinal Pigment Epithelial Cells In Vitro Free
PDF
Ana L. Gramajo; Leandro C. Zacharias; Aneesh Neekhra; Saurabh Luthra; Shari R. Atilano; Marilyn Chwa; Donald J. Brown; Baruch D. Kuppermann; M. Cristina Kenney
Tags: dna, mitochondrial, retinal pigment cell, mitochondria, polymerase chain reaction, superoxides
Investigative Ophthalmology & Visual Science February 2010, Vol.51, 1164-1170. doi:https://doi.org/10.1167/iovs.09-3443
Synthesis of Sphingosine Is Essential for Oxidative Stress-Induced Apoptosis of Photoreceptors Free
PDF
Carolina E. Abrahan; Gisela E. Miranda; Daniela L. Agnolazza; Luis E. Politi; Nora P. Rotstein
Tags: apoptosis, photoreceptors, sphingosine, stress, ceramides
Investigative Ophthalmology & Visual Science February 2010, Vol.51, 1171-1180. doi:https://doi.org/10.1167/iovs.09-3909
Generation of Light-Sensitive Photoreceptor Phenotypes by Genetic Modification of Human Adult Ocular Stem Cells with Crx Free
PDF
Catherine Jomary; Stephen E. Jones; Andrew J. Lotery
Tags: adult, genetics, phenotype, photoreceptors, stem cells
Investigative Ophthalmology & Visual Science February 2010, Vol.51, 1181-1189. doi:https://doi.org/10.1167/iovs.09-4385
Vascular Endothelial Growth Factor as an Autocrine Survival Factor for Retinal Pigment Epithelial Cells under Oxidative Stress via the VEGF-R2/PI3K/Akt Free
PDF
Suk Ho Byeon; Sung Chul Lee; Soo Hyun Choi; Hyung-Keun Lee; Joon H. Lee; Young Kwang Chu; Oh Woong Kwon
Tags: autocrine, coefficient of determination, oxidative stress, retinal pigment cell, transverse spin relaxation rate
Investigative Ophthalmology & Visual Science February 2010, Vol.51, 1190-1197. doi:https://doi.org/10.1167/iovs.09-4144
Protection of Retinal Ganglion Cells by Caspase Substrate-Binding Peptide IQACRG from N-Methyl-d-Aspartate Receptor-Mediated Excitotoxicity Free
PDF
Masaaki Seki; Walid Soussou; Shin-ichi Manabe; Stuart A. Lipton
Tags: aspartate, caspases, excitotoxicity, intravitreal injections, n-methylaspartate
Investigative Ophthalmology & Visual Science February 2010, Vol.51, 1198-1207. doi:https://doi.org/10.1167/iovs.09-4102

Visual Neuroscience

Visual Response Properties of Y Cells in the Detached Feline Retina Free
PDF
Yan Nan; Chunxia Xiao; Baiyu Chen; Rutledge G. Ellis-Behnke; Kwok-Fai So; Mingliang Pu
Tags: cats, retina, retinal detachment, luminance
Investigative Ophthalmology & Visual Science February 2010, Vol.51, 1208-1215. doi:https://doi.org/10.1167/iovs.09-4179
Electrophysiological Evidence of Early Functional Damage in Glaucoma and Ocular Hypertension Free
PDF
Rachel V. North; Adrian L. Jones; Neville Drasdo; John M. Wild; James E. Morgan
Tags: diagnostic imaging, electroretinography, glaucoma, ocular hypertension, open-angle glaucoma
Investigative Ophthalmology & Visual Science February 2010, Vol.51, 1216-1222. doi:https://doi.org/10.1167/iovs.09-3409

Visual Psychophysics and Physiological Optics

Spatiotemporal Interactions in Retinal Prosthesis Subjects Free
PDF
Alan Horsager; Robert J. Greenberg; Ione Fine
Tags: visual prosthesis
Investigative Ophthalmology & Visual Science February 2010, Vol.51, 1223-1233. doi:https://doi.org/10.1167/iovs.09-3746
Presbyopic Spectacle Coverage, Willingness to Pay for Near Correction, and the Impact of Correcting Uncorrected Presbyopia in Adults in Zanzibar, East Africa Free
PDF
Heidi R. Laviers; Fatma Omar; Hakika Jecha; Garnia Kassim; Clare Gilbert
Tags: adult, eyeglasses, follow-up, presbyopia, africa, eastern
Investigative Ophthalmology & Visual Science February 2010, Vol.51, 1234-1241. doi:https://doi.org/10.1167/iovs.08-3154
Enhanced Contrast Sensitivity Confirms Active Compensation in Blur Adaptation Free
PDF
Narayanan Rajeev; Andrew Metha
Tags: contrast sensitivity, spatial frequency, lens (device), lens, crystalline
Investigative Ophthalmology & Visual Science February 2010, Vol.51, 1242-1246. doi:https://doi.org/10.1167/iovs.09-3965
Small Effect of Interline Spacing on Maximal Reading Speed in Low-Vision Patients with Central Field Loss Irrespective of Scotoma Size Free
PDF
Aurélie Calabrèse; Jean-Baptiste Bernard; Louis Hoffart; Géraldine Faure; Fatiha Barouch; John Conrath; Eric Castet
Tags: reading speed, scotoma, visual impairment, eye
Investigative Ophthalmology & Visual Science February 2010, Vol.51, 1247-1254. doi:https://doi.org/10.1167/iovs.09-3682
Basic Quantitative Assessment of Visual Performance in Patients with Very Low Vision Free
PDF
Michael Bach; Michaela Wilke; Barbara Wilhelm; Eberhart Zrenner; Robert Wilke
Tags: motion, visual impairment, vision, eye, visual prosthesis
Investigative Ophthalmology & Visual Science February 2010, Vol.51, 1255-1260. doi:https://doi.org/10.1167/iovs.09-3512

Clinical Trials

Normative Measurements of the Chinese Extraocular Musculature by High-Field Magnetic Resonance Imaging Free
PDF
Sunny Shen; Kee Siew Fong; Hwee Bee Wong; Audrey Looi; Ling Ling Chan; Jack Rootman; Lay Leng Seah
Tags: chinese (other dialects), chinese people, magnetic resonance imaging, muscle
Investigative Ophthalmology & Visual Science February 2010, Vol.51, 631-636. doi:https://doi.org/10.1167/iovs.09-3614
Concordance of Disease Progression in Bilateral Geographic Atrophy Due to AMD Free
PDF
Monika Fleckenstein; Christine Adrion; Steffen Schmitz-Valckenberg; Arno P. Göbel; Almut Bindewald-Wittich; Hendrik P. N. Scholl; Ulrich Mansmann; Frank G. Holz; for the FAM Study Group
Tags: atrophy, disease progression, eye, visual acuity, atrophic condition of skin
Investigative Ophthalmology & Visual Science February 2010, Vol.51, 637-642. doi:https://doi.org/10.1167/iovs.09-3547
Expression of CXCL9, -10, -11, and CXCR3 in the Tear Film and Ocular Surface of Patients with Dry Eye Syndrome Free
PDF
Kyung-Chul Yoon; Chang-Soo Park; In-Cheon You; Hwan-Jun Choi; Kwang-Hoon Lee; Seong-Kyu Im; Hong-Yong Park; Stephen C. Pflugfelder
Tags: dry eye syndromes, tear film finding, sjogren's syndrome, chemokines
Investigative Ophthalmology & Visual Science February 2010, Vol.51, 643-650. doi:https://doi.org/10.1167/iovs.09-3425
Copyright © 2025 Association for Research in Vision and Ophthalmology.
×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×
This site uses cookies. By continuing to use our website, you are agreeing to our privacy policy.Accept