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Anatomy and Pathology/Oncology

Serum DJ-1/PARK 7 Is a Potential Biomarker of Choroidal Nevi Transformation Free
PDF
Manuel F. Bande; Maria Santiago; Maria Jose Blanco; Purificacion Mera; Carmela Capeans; Maria Xose Rodríguez-Alvarez; Maria Pardo; Antonio Piñeiro
Tags: biological markers, nevus, risk factors
Investigative Ophthalmology & Visual Science January 2012, Vol.53, 62-67. doi:https://doi.org/10.1167/iovs.11-7948
The Vitreous Glycoprotein Opticin Inhibits Preretinal Neovascularization Free
PDF
Magali M. Le Goff; Hongbin Lu; Marta Ugarte; Stephen Henry; Masamine Takanosu; Richard Mayne; Paul N. Bishop
Tags: eye, glycoproteins, mice, neovascularization, pathologic, vitreous body
Investigative Ophthalmology & Visual Science January 2012, Vol.53, 228-234. doi:https://doi.org/10.1167/iovs.11-8514
Alterations in Protein Expression in Tree Shrew Sclera during Development of Lens-Induced Myopia and Recovery Free
PDF
Michael R. Frost; Thomas T. Norton
Tags: lens (device), myopia, proteins, recovery of function, sclera
Investigative Ophthalmology & Visual Science January 2012, Vol.53, 322-336. doi:https://doi.org/10.1167/iovs.11-8354

Biochemistry and Molecular Biology

Lysosomal Phospholipase A2 Activity in Pig Aqueous Humor Free
PDF
Akira Abe; Miki Hiraoka; Shuichiro Inatomi; Ikuyo Ohguro; Hiroshi Ohguro
Tags: aqueous humor, body tissue, hypertension, phospholipase, liposomes
Investigative Ophthalmology & Visual Science January 2012, Vol.53, 152-156. doi:https://doi.org/10.1167/iovs.11-7891
Transduction of PTEN Proteins Using the Tat Domain Modulates TGF-β1–Mediated Signaling Pathways and Transdifferentiation in Subconjunctival Fibroblasts Free
PDF
Eun Jee Chung; Hyung Keun Lee; Sun-Ah Jung; Seung Jae Lee; Hee Youn Chee; Yong Ho Sohn; Joon H. Lee
Tags: fibroblasts, fusion proteins, proteins, pten gene, cell transdifferentiation
Investigative Ophthalmology & Visual Science January 2012, Vol.53, 379-386. doi:https://doi.org/10.1167/iovs.11-8491
ADAMTSL4, a Secreted Glycoprotein Widely Distributed in the Eye, Binds Fibrillin-1 Microfibrils and Accelerates Microfibril Biogenesis Free
PDF
Luis A. R. Gabriel; Lauren W. Wang; Hannah Bader; Jason C. Ho; Alana K. Majors; Joe G. Hollyfield; Elias I. Traboulsi; Suneel S. Apte
Tags: eye, fibrillins, glycoproteins, microfibrils, origin of life
Investigative Ophthalmology & Visual Science January 2012, Vol.53, 461-469. doi:https://doi.org/10.1167/iovs.10-5955

Clinical and Epidemiologic Research

Heritability of Peripheral Refraction in Chinese Children and Adolescents: The Guangzhou Twin Eye Study Free
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Xiaohu Ding; Zhi Lin; Qunxiao Huang; Yingfeng Zheng; Nathan Congdon; Mingguang He
Tags: adolescent, child, chinese (other dialects), chinese people, eye
Investigative Ophthalmology & Visual Science January 2012, Vol.53, 107-111. doi:https://doi.org/10.1167/iovs.11-8716
Anterior Segment Optical Coherence Tomography Study of the Cornea and Anterior Segment in Adult Ethnic South Asian Indian Eyes Free
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Marcus Ang; Wesley Chong; Wan Ting Tay; Leonard Yuen; Tien Yin Wong; Ming-Guang He; Seang Mei Saw; Tin Aung; Jodhbir S. Mehta
Tags: adult, asian indians, cornea, eye, optical coherence tomography
Investigative Ophthalmology & Visual Science January 2012, Vol.53, 120-125. doi:https://doi.org/10.1167/iovs.11-8386
Diagnostic Characteristics of Tests for Ocular Chlamydia after Mass Azithromycin Distributions Free
PDF
Jeremy D. Keenan; Craig W. See; Jeanne Moncada; Berhan Ayele; Teshome Gebre; Nicole E. Stoller; Charles E. McCulloch; Travis C. Porco; Bruce D. Gaynor; Paul M. Emerson; Julius Schachter; Thomas M. Lietman
Tags: azithromycin, chlamydia, dna, rna, trachoma
Investigative Ophthalmology & Visual Science January 2012, Vol.53, 235-240. doi:https://doi.org/10.1167/iovs.11-8493
Relationship between Air Pollution and Outpatient Visits for Nonspecific Conjunctivitis Free
PDF
Chia-Jen Chang; Hsi-Hsien Yang; Chin-An Chang; Hsien-Yang Tsai
Tags: air pollution, conjunctivitis, outpatients
Investigative Ophthalmology & Visual Science January 2012, Vol.53, 429-433. doi:https://doi.org/10.1167/iovs.11-8253
Refractive Error and Presbyopia in Timor-Leste: The Impact of 5 Years of a National Spectacle Program Free
PDF
Jacqueline Ramke; Garry Brian; Thomas Naduvilath
Tags: presbyopia, refractive errors, eyeglasses, surveys
Investigative Ophthalmology & Visual Science January 2012, Vol.53, 434-439. doi:https://doi.org/10.1167/iovs.11-8161
Elevated Blood Pressure is Associated with Rarefaction of the Retinal Vasculature in Children Free
PDF
Emil D. Kurniawan; Ning Cheung; Carol Y. Cheung; Wan Ting Tay; Seang Mei Saw; Tien Yin Wong
Tags: child, fractals, hypertension, retinal vasculature, blood pressure
Investigative Ophthalmology & Visual Science January 2012, Vol.53, 470-474. doi:https://doi.org/10.1167/iovs.11-8835

Cornea

Role of Epithelial–Mesenchymal Transition in Repair of the Lacrimal Gland after Experimentally Induced Injury Free
PDF
Samantha You; Orna Avidan; Ayesha Tariq; Ivy Ahluwalia; Paul C. Stark; Claire L. Kublin; Driss Zoukhri
Tags: epithelium, lacrimal gland, vimentin, wounds and injuries, western blotting
Investigative Ophthalmology & Visual Science January 2012, Vol.53, 126-135. doi:https://doi.org/10.1167/iovs.11-7893
Brillouin Optical Microscopy for Corneal Biomechanics Free
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Giuliano Scarcelli; Roberto Pineda; Seok Hyun Yun
Tags: cornea, optics, corneal collagen cross-linking, biomechanics, diagnostic imaging
Investigative Ophthalmology & Visual Science January 2012, Vol.53, 185-190. doi:https://doi.org/10.1167/iovs.11-8281
Therapeutic Effects of Epidermal Growth Factor on Benzalkonium Chloride–Induced Dry Eye in a Mouse Model Free
PDF
Xinye Xiao; Huan He; Zhirong Lin; Pingping Luo; Hui He; Tong Zhou; Yueping Zhou; Zuguo Liu
Tags: benzalkonium chloride, dry eye syndromes, epidermal growth factor, mice, bronchioloalveolar carcinoma
Investigative Ophthalmology & Visual Science January 2012, Vol.53, 191-197. doi:https://doi.org/10.1167/iovs.11-8553
Analysis of the Role of ZEB1 in the Pathogenesis of Posterior Polymorphous Corneal Dystrophy Free
PDF
Vivek S. Yellore; Sylvia A. Rayner; Catherine K. Nguyen; Rajendra K. Gangalum; Zhe Jing; Suraj P. Bhat; Anthony J. Aldave
Tags: cornea, pathogenesis, polymorphous corneal dystrophy, promoter regions (genetics), proteins
Investigative Ophthalmology & Visual Science January 2012, Vol.53, 273-278. doi:https://doi.org/10.1167/iovs.11-8038
Isolation and Expansion of Human Limbal Stromal Niche Cells Free
PDF
Hua-Tao Xie; Szu-Yu Chen; Gui-Gang Li; Scheffer C. G. Tseng
Tags: cardiac support procedures, collagenase, epithelial cells, epithelium, mast-cell sarcoma
Investigative Ophthalmology & Visual Science January 2012, Vol.53, 279-286. doi:https://doi.org/10.1167/iovs.11-8441
Differences in Human Meibum Lipid Composition with Meibomian Gland Dysfunction Using NMR and Principal Component Analysis Free
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Douglas Borchman; Gary N. Foulks; Marta C. Yappert; Sarah E. Milliner
Tags: lipids, meibomian gland, pathophysiology, principal component analysis
Investigative Ophthalmology & Visual Science January 2012, Vol.53, 337-347. doi:https://doi.org/10.1167/iovs.11-8551
Changes in Human Meibum Lipid Composition with Age Using Nuclear Magnetic Resonance Spectroscopy Free
PDF
Douglas Borchman; Gary N. Foulks; Marta C. Yappert; Sarah E. Milliner
Tags: lipids, nuclear magnetic resonance, spectrum analysis, adult, infant
Investigative Ophthalmology & Visual Science January 2012, Vol.53, 475-482. doi:https://doi.org/10.1167/iovs.11-8341
Characterization of Ocular Surface Epithelial and Progenitor Cell Markers in Human Adipose Stromal Cells Derived from Lipoaspirates Free
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Eva M. Martínez-Conesa; Enric Espel; Manuel Reina; Ricardo P. Casaroli-Marano
Tags: adhesions, epithelium, polymerase chain reaction, stem cells, stromal cells
Investigative Ophthalmology & Visual Science January 2012, Vol.53, 513-520. doi:https://doi.org/10.1167/iovs.11-7550
Microkeratome-Assisted Preparation of Ultrathin Grafts for Descemet Stripping Automated Endothelial Keratoplasty Free
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Massimo Busin; Amit K. Patel; Vincenzo Scorcia; Diego Ponzin
Tags: endothelium, keratoplasty, tissue transplants, body tissue, cornea
Investigative Ophthalmology & Visual Science January 2012, Vol.53, 521-524. doi:https://doi.org/10.1167/iovs.11-7753
Noninvasive In Vivo Assessment of Soft Contact Lens Type on Tear Film Surface Quality Free
PDF
Dorota H. Szczesna-Iskander; D. Robert Iskander; Scott A. Read; David Alonso-Caneiro
Tags: contact lenses, hydrophilic, lens (device), lens, crystalline, tear film finding, contact lenses
Investigative Ophthalmology & Visual Science January 2012, Vol.53, 525-531. doi:https://doi.org/10.1167/iovs.11-8257

Eye Movements, Strabismus, Amblyopia and Neuro-ophthalmology

Accuracy of Funduscopy to Identify True Edema versus Pseudoedema of the Optic Disc Free
PDF
Arturo Carta; Stefania Favilla; Marco Prato; Stefania Bianchi-Marzoli; Alfredo A. Sadun; Paolo Mora
Tags: edema, ophthalmoscopy, optic disk
Investigative Ophthalmology & Visual Science January 2012, Vol.53, 1-6. doi:https://doi.org/10.1167/iovs.11-8082
Effects of the Sustained Release of IGF-1 on Extraocular Muscle of the Infant Non-Human Primate: Adaptations at the Effector Organ Level Free
PDF
Christy L. Willoughby; Stephen P. Christiansen; Michael J. Mustari; Linda K. McLoon
Tags: infant, insulin-like growth factor i, primates, muscle, muscle of orbit
Investigative Ophthalmology & Visual Science January 2012, Vol.53, 68-75. doi:https://doi.org/10.1167/iovs.11-8356
Abnormal Achromatic and Chromatic Contrast Sensitivity in Neurofibromatosis Type 1 Free
PDF
Maria José Ribeiro; Inês Ribeiro Violante; Inês Bernardino; Fabiana Ramos; Jorge Saraiva; Pablo Reviriego; Meena Upadhyaya; Eduardo Duarte Silva; Miguel Castelo-Branco
Tags: contrast sensitivity, neurofibromatoses, neurofibromatosis 1
Investigative Ophthalmology & Visual Science January 2012, Vol.53, 287-293. doi:https://doi.org/10.1167/iovs.11-8225
Influence of Background Complexity on Visual Sensitivity and Binocular Summation Using Patterns with and without Noise Free
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Akemi Wakayama; Chota Matsumoto; Kazuyo Ohmure; Masahiko Inase; Yoshikazu Shimomura
Tags: noise, summation
Investigative Ophthalmology & Visual Science January 2012, Vol.53, 387-393. doi:https://doi.org/10.1167/iovs.11-8022

Genetics

A Zebrafish Model of Axenfeld-Rieger Syndrome Reveals That pitx2 Regulation by Retinoic Acid Is Essential for Ocular and Craniofacial Development Free
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Brenda L. Bohnsack; Daniel S. Kasprick; Phillip E. Kish; Daniel Goldman; Alon Kahana
Tags: embryo, zebrafish, syndrome, rna, messenger, eye
Investigative Ophthalmology & Visual Science January 2012, Vol.53, 7-22. doi:https://doi.org/10.1167/iovs.11-8494
A Single-Base Substitution in the Seed Region of miR-184 Causes EDICT Syndrome Free
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Benjamin W. Iliff; S. Amer Riazuddin; John D. Gottsch
Tags: seeds, syndrome
Investigative Ophthalmology & Visual Science January 2012, Vol.53, 348-353. doi:https://doi.org/10.1167/iovs.11-8783
Common Polymorphisms in the SERPINI2 Gene Are Associated with Refractive Error in the 1958 British Birth Cohort Free
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Pirro G. Hysi; Claire L. Simpson; Yvonne K. Y. Fok; Dianne Gerrelli; Andrew R. Webster; Shomi S. Bhattacharya; Christopher J. Hammond; Pak C. Sham; Jugnoo S. Rahi
Tags: birth, cohort studies, genes, polymorphism, refractive errors
Investigative Ophthalmology & Visual Science January 2012, Vol.53, 440-447. doi:https://doi.org/10.1167/iovs.10-5640
Nonsense-Mediated Decay as the Molecular Cause for Autosomal Recessive Bestrophinopathy in Two Unrelated Families Free
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Esther Pomares; Anniken Burés-Jelstrup; Sheila Ruiz-Nogales; Borja Corcóstegui; Roser González-Duarte; Rafael Navarro
Tags: autosomal recessive inheritance, family, mutation, reverse transcriptase polymerase chain reaction, phenotype
Investigative Ophthalmology & Visual Science January 2012, Vol.53, 532-537. doi:https://doi.org/10.1167/iovs.11-7964
JAK2 and STAT3 Polymorphisms in a Han Chinese Population with Behçet's Disease Free
PDF
Ke Hu; Shengping Hou; Zhengxuan Jiang; Aize Kijlstra; Peizeng Yang
Tags: behcet syndrome, chinese (other dialects), chinese people, polymorphism, stat3 protein
Investigative Ophthalmology & Visual Science January 2012, Vol.53, 538-541. doi:https://doi.org/10.1167/iovs.11-8440

Glaucoma

Involvement of EphB/Ephrin-B Signaling in Axonal Survival in Mouse Experimental Glaucoma Free
PDF
Christine T. Fu; David Sretavan
Tags: axon, ephrins, glaucoma, mice, optic nerve
Investigative Ophthalmology & Visual Science January 2012, Vol.53, 76-84. doi:https://doi.org/10.1167/iovs.11-8546
Effects of Aging on 24-Hour Intraocular Pressure Measurements in Sitting and Supine Body Positions Free
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Kaweh Mansouri; Robert N. Weinreb; John H. K. Liu
Tags: aging, intraocular pressure, posture, sitting position, supine position
Investigative Ophthalmology & Visual Science January 2012, Vol.53, 112-116. doi:https://doi.org/10.1167/iovs.11-8763
Three-Dimensional Evaluation of the Lamina Cribrosa Using Spectral-Domain Optical Coherence Tomography in Glaucoma Free
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Eun Ji Lee; Tae-Woo Kim; Robert N. Weinreb; Min Hee Suh; Myungjoo Kang; Ki Ho Park; Seok Hwan Kim; Dong Myung Kim
Tags: cribriform plate, glaucoma, optic disk, optical coherence tomography, diagnostic imaging
Investigative Ophthalmology & Visual Science January 2012, Vol.53, 198-204. doi:https://doi.org/10.1167/iovs.11-7848
Multiplex Cytokine Analysis of Aqueous Humor in Eyes with Primary Open-Angle Glaucoma, Exfoliation Glaucoma, and Cataract Free
PDF
Yasuyuki Takai; Masaki Tanito; Akihiro Ohira
Tags: aqueous humor, cataract, cytokine, eye, glaucoma
Investigative Ophthalmology & Visual Science January 2012, Vol.53, 241-247. doi:https://doi.org/10.1167/iovs.11-8434
Spectral-Domain Optical Coherence Tomography Enhanced Depth Imaging of the Normal and Glaucomatous Nonhuman Primate Optic Nerve Head Free
PDF
Hongli Yang; Jingjing Qi; Christy Hardin; Stuart K. Gardiner; Nicholas G. Strouthidis; Brad Fortune; Claude F. Burgoyne
Tags: cribriform plate, diagnostic imaging, eye, glaucoma, optic disk
Investigative Ophthalmology & Visual Science January 2012, Vol.53, 394-405. doi:https://doi.org/10.1167/iovs.11-8244
2-D Pattern of Nerve Fiber Bundles in Glaucoma Emerging from Spectral-Domain Optical Coherence Tomography Free
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Mona K. Garvin; Michael D. Abràmoff; Kyungmoo Lee; Meindert Niemeijer; Milan Sonka; Young H. Kwon
Tags: glaucoma, nerve fibers, optical coherence tomography
Investigative Ophthalmology & Visual Science January 2012, Vol.53, 483-489. doi:https://doi.org/10.1167/iovs.11-8349

Immunology and Microbiology

An Optical Coherence Tomography Study on Degeneration of Retinal Nerve Fiber Layer in Rats with Autoimmune Optic Neuritis Free
PDF
Katharina Hein; Ivana Gadjanski; Benedikt Kretzschmar; Katharina Lange; Ricarda Diem; Muriel B. Sättler; Mathias Bähr
Tags: autoimmunity, optic neuritis, optical coherence tomography, rats, retinal nerve fiber layer
Investigative Ophthalmology & Visual Science January 2012, Vol.53, 157-163. doi:https://doi.org/10.1167/iovs.11-8092
Vitreal IgM Autoantibodies Target Neurofilament Medium in a Spontaneous Model of Autoimmune Uveitis Free
PDF
Margarete E. Swadzba; Sieglinde Hirmer; Barbara Amann; Stefanie M. Hauck; Cornelia A. Deeg
Tags: autoantibodies, autoimmune diseases, autoimmunity, immunoglobulin m, uveitis
Investigative Ophthalmology & Visual Science January 2012, Vol.53, 294-300. doi:https://doi.org/10.1167/iovs.11-8734
αβ TCR+ T Cells, but Not B Cells, Promote Autoimmune Keratitis in B10 Mice Lacking γδ T Cells Free
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Rebecca L. O'Brien; Jennifer L. Chain; M. Kemal Aydintug; Dawn Bohrer-Kunter; Yafei Huang; Ian R. Hardy; John C. Cambier; Kevin Lahmers; Tanja Nuhsbaum; Richard Davidson; Deming Sun; Willi K. Born
Tags: keratitis, mice, t-lymphocytes, autoimmune diseases, b-lymphocytes
Investigative Ophthalmology & Visual Science January 2012, Vol.53, 301-308. doi:https://doi.org/10.1167/iovs.11-8855
Neuroprotective Effects of Recombinant T-cell Receptor Ligand in Autoimmune Optic Neuritis in HLA-DR2 Mice Free
PDF
Grazyna Adamus; Lori Brown; Shayne Andrew; Roberto Meza-Romero; Gregory G. Burrows; Arthur A. Vandenbark
Tags: autoimmune diseases, hla-dr2 antigen, inflammation, ligands, mice
Investigative Ophthalmology & Visual Science January 2012, Vol.53, 406-412. doi:https://doi.org/10.1167/iovs.11-8419
Traversal of Multilayered Corneal Epithelia by Cytotoxic Pseudomonas aeruginosa Requires the Phospholipase Domain of ExoU Free
PDF
Julio C. Ramirez; Suzanne M. J. Fleiszig; Aaron B. Sullivan; Connie Tam; Roya Borazjani; David J. Evans
Tags: corneal epithelium, epithelium, phospholipase, pseudomonas aeruginosa, bacteria
Investigative Ophthalmology & Visual Science January 2012, Vol.53, 448-453. doi:https://doi.org/10.1167/iovs.11-8999

Lens

A Fully Human In Vitro Capsular Bag Model to Permit Intraocular Lens Evaluation Free
PDF
Lucy J. Dawes; Christopher D. Illingworth; I. Michael Wormstone
Tags: intraocular lens implant device, lens, crystalline, cataract surgery, lens (device), polymethyl methacrylate
Investigative Ophthalmology & Visual Science January 2012, Vol.53, 23-29. doi:https://doi.org/10.1167/iovs.11-8851
Protective Effect of the Thioltransferase Gene on In Vivo UVR-300 nm–Induced Cataract Free
PDF
Martin Kronschläger; Konstantin Galichanin; Joakim Ekström; Marjorie F. Lou; Per G. Söderberg
Tags: cataract, genes, lens (device), lens, crystalline, mice
Investigative Ophthalmology & Visual Science January 2012, Vol.53, 248-252. doi:https://doi.org/10.1167/iovs.11-8504
Ocular Biocompatibility of Nitinol Intraocular Clips Free
PDF
Jeffrey L. Olson; Raul Velez-Montoya; Michael Erlanger
Tags: biocompatibility, intraocular surgical clips, nitinol, surgical procedures, operative, sutures
Investigative Ophthalmology & Visual Science January 2012, Vol.53, 354-360. doi:https://doi.org/10.1167/iovs.11-8496

Nantotechnology and Regenerative Medicine

Subretinal Delivery of Ultrathin Rigid-Elastic Cell Carriers Using a Metallic Shooter Instrument and Biodegradable Hydrogel Encapsulation Free
PDF
Boris V. Stanzel; Zengping Liu; Ralf Brinken; Norbert Braun; Frank G. Holz; Nicole Eter
Tags: implants, hydrogel, muscle rigidity, encapsulation, gelatin
Investigative Ophthalmology & Visual Science January 2012, Vol.53, 490-500. doi:https://doi.org/10.1167/iovs.11-8260

Physiology and Pharmacology

Acute Retinal Ischemia Inhibits Endothelium-Dependent Nitric Oxide–Mediated Dilation of Retinal Arterioles via Enhanced Superoxide Production Free
PDF
Travis W. Hein; Yi Ren; Luke B. Potts; Zhaoxu Yuan; Enoch Kuo; Robert H. Rosa, Jr; Lih Kuo
Tags: arteriole, dilatation, pathologic, endothelium, nitric oxide, retinal ischemia
Investigative Ophthalmology & Visual Science January 2012, Vol.53, 30-36. doi:https://doi.org/10.1167/iovs.11-8753
Effect of Circadian Clock Gene Mutations on Nonvisual Photoreception in the Mouse Free
PDF
Leah Owens; Ethan Buhr; Daniel C. Tu; Tamara L. Lamprecht; Janet Lee; Russell N. Van Gelder
Tags: clock gene, mice, mutation, retinal degeneration, pupil
Investigative Ophthalmology & Visual Science January 2012, Vol.53, 454-460. doi:https://doi.org/10.1167/iovs.11-8717

Retina

Retinal Venular Caliber Predicts Visual Outcome after Intravitreal Ranibizumab Injection Treatments for Neovascular AMD Free
PDF
Sanjeewa S. Wickremasinghe; Lucy Busija; Robyn H. Guymer; Tien Y. Wong; Salmaan Qureshi
Tags: diameter, exudative age-related macular degeneration, eye, ranibizumab, vision
Investigative Ophthalmology & Visual Science January 2012, Vol.53, 37-41. doi:https://doi.org/10.1167/iovs.11-7689
Experimental Endoscopic Endovascular Cannulation: A Novel Approach to Thrombolysis in Retinal Vessel Occlusion Free
PDF
Lars-Olof Hattenbach; Joachim Puchta; Ingo Hilgenberg
Tags: catheterization, endoscopy, retinal vessels, thrombolytic therapy, puncture wound
Investigative Ophthalmology & Visual Science January 2012, Vol.53, 42-46. doi:https://doi.org/10.1167/iovs.11-8486
Correlation between Macular Morphology and Sensitivity in Patients with Retinitis Pigmentosa and Hyperautofluorescent Ring Free
PDF
Eva Lenassi; Eric Troeger; Robert Wilke; Marko Hawlina
Tags: language morphology, morphology, perimetry, retinitis pigmentosa, fundus autofluorescence imaging
Investigative Ophthalmology & Visual Science January 2012, Vol.53, 47-52. doi:https://doi.org/10.1167/iovs.11-8048
Noninvasive Imaging of the Foveal Avascular Zone with High-Speed, Phase-Variance Optical Coherence Tomography Free
PDF
Dae Yu Kim; Jeff Fingler; Robert J. Zawadzki; Susanna S. Park; Lawrence S. Morse; Daniel M. Schwartz; Scott E. Fraser; John S. Werner
Tags: diagnostic imaging, heterogeneity of variance, optical coherence tomography, blood capillaries, parafoveal region
Investigative Ophthalmology & Visual Science January 2012, Vol.53, 85-92. doi:https://doi.org/10.1167/iovs.11-8249
Automated Characterization of Pigment Epithelial Detachment by Optical Coherence Tomography Free
PDF
Sun Young Lee; Paul F. Stetson; Humberto Ruiz-Garcia; Florian M. Heussen; SriniVas R. Sadda
Tags: optical coherence tomography, parent's evaluation of developmental status, retinal pigment epithelial detachment
Investigative Ophthalmology & Visual Science January 2012, Vol.53, 164-170. doi:https://doi.org/10.1167/iovs.11-8188
The Source of Moving Particles in Parafoveal Capillaries Detected by Adaptive Optics Scanning Laser Ophthalmoscopy Free
PDF
Akihito Uji; Masanori Hangai; Sotaro Ooto; Kohei Takayama; Naoko Arakawa; Hiroshi Imamura; Koji Nozato; Nagahisa Yoshimura
Tags: blood capillaries, exanthema, optics, parafoveal region, scanning laser ophthalmoscopy
Investigative Ophthalmology & Visual Science January 2012, Vol.53, 171-178. doi:https://doi.org/10.1167/iovs.11-8192
Correlation of Fundus Autofluorescence Gray Values with Vision and Microperimetry in Resolved Central Serous Chorioretinopathy Free
PDF
Jaeryung Oh; Seong-Woo Kim; Soon-Sun Kwon; In Kyung Oh; Kuhl Huh
Tags: central serous chorioretinopathy, fundus autofluorescence imaging, vision
Investigative Ophthalmology & Visual Science January 2012, Vol.53, 179-184. doi:https://doi.org/10.1167/iovs.11-8704
Multifocal Pupillography Identifies Ranibizumab-Induced Changes in Retinal Function for Exudative Age-Related Macular Degeneration Free
PDF
Faran Sabeti; Ted Maddess; Rohan W. Essex; Andrew C. James
Tags: exudative age-related macular degeneration, ranibizumab
Investigative Ophthalmology & Visual Science January 2012, Vol.53, 253-260. doi:https://doi.org/10.1167/iovs.11-8004
Diurnal Variation of Choroidal Thickness in Normal, Healthy Subjects Measured by Spectral Domain Optical Coherence Tomography Free
PDF
Colin S. Tan; Yanling Ouyang; Humberto Ruiz; SriniVas R. Sadda
Tags: circadian rhythms, optical coherence tomography, choroid
Investigative Ophthalmology & Visual Science January 2012, Vol.53, 261-266. doi:https://doi.org/10.1167/iovs.11-8782
Novel Noninvasive Detection of the Fovea Avascular Zone Using Confocal Red-Free Imaging in Diabetic Retinopathy and Retinal Vein Occlusion Free
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Yong Un Shin; Sungmin Kim; Byung Ro Lee; Joong Won Shin; Sun I. Kim
Tags: diabetic retinopathy, diagnostic imaging, fovea centralis, retinal vein occlusion
Investigative Ophthalmology & Visual Science January 2012, Vol.53, 309-315. doi:https://doi.org/10.1167/iovs.11-8510
Interocular Symmetry of Abnormal Multifocal Electroretinograms in Adolescents with Diabetes and No Retinopathy Free
PDF
Michal Laron; Marcus A. Bearse, Jr; Kevin Bronson-Castain; Soffia Jonasdottir; Barbara King-Hooper; Shirin Barez; Marilyn E. Schneck; Anthony J. Adams
Tags: adolescent, diabetes mellitus, diabetes mellitus, type 2, electroretinography, eye
Investigative Ophthalmology & Visual Science January 2012, Vol.53, 316-321. doi:https://doi.org/10.1167/iovs.11-8825
Profiling Retinal Biochemistry in the MPDZ Mutant Retinal Dysplasia and Degeneration Chick: A Model of Human RP and LCA Free
PDF
James R. Beattie; Sorcha Finnegan; Ross W. Hamilton; Manir Ali; Christopher F. Inglehearn; Alan W. Stitt; John J. McGarvey; Paul M. Hocking; William J. Curry
Tags: biochemistry, retina, retinal dysplasia, sinus histiocytosis, tissue degeneration
Investigative Ophthalmology & Visual Science January 2012, Vol.53, 413-420. doi:https://doi.org/10.1167/iovs.11-8591
Generation of an Inbred Miniature Pig Model of Retinitis Pigmentosa Free
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Jason W. Ross; Juan P. Fernandez de Castro; Jianguo Zhao; Melissa Samuel; Eric Walters; Cecilia Rios; Patricia Bray-Ward; Bryan W. Jones; Robert E. Marc; Wei Wang; Liang Zhou; Jennifer M. Noel; Maureen A. McCall; Paul J. DeMarco; Randall S. Prather; Henry J. Kaplan
Tags: animals, transgenic, retinitis pigmentosa, suidae, transgenes, rhodopsin
Investigative Ophthalmology & Visual Science January 2012, Vol.53, 501-507. doi:https://doi.org/10.1167/iovs.11-8784
C9-R95X Polymorphism in Patients with Neovascular Age-Related Macular Degeneration Free
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Koji M. Nishiguchi; Tetsuhiro R. Yasuma; Daisuke Tomida; Makoto Nakamura; Kohei Ishikawa; Masato Kikuchi; Yuhsuke Ohmi; Toshimitsu Niwa; Nobuyuki Hamajima; Koichi Furukawa; Hiroko Terasaki
Tags: choroidal neovascularization, exudative age-related macular degeneration, polymorphism, vascular endothelial growth factor a, lasers
Investigative Ophthalmology & Visual Science January 2012, Vol.53, 508-512. doi:https://doi.org/10.1167/iovs.11-8425

Retinal Cell Biology

Vitreous IGFBP-3 Effects on Müller Cell Proliferation and Tractional Force Generation Free
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Jeffery L. King; Clyde Guidry
Tags: cell proliferation, insulin-like growth factor binding protein 3, insulin-like growth factor i, insulin-like growth factor ii, vitreous body
Investigative Ophthalmology & Visual Science January 2012, Vol.53, 93-99. doi:https://doi.org/10.1167/iovs.11-8683
Prominin-1 Localizes to the Open Rims of Outer Segment Lamellae in Xenopus laevis Rod and Cone Photoreceptors Free
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Zhou Han; David W. Anderson; David S. Papermaster
Tags: antibodies, proteins, retinal cone, rod photoreceptors, photoreceptors
Investigative Ophthalmology & Visual Science January 2012, Vol.53, 361-373. doi:https://doi.org/10.1167/iovs.11-8635

Translational

TUDCA Slows Retinal Degeneration in Two Different Mouse Models of Retinitis Pigmentosa and Prevents Obesity in Bardet-Biedl Syndrome Type 1 Mice Free
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Arlene V. Drack; Alina V. Dumitrescu; Sajag Bhattarai; Daniel Gratie; Edwin M. Stone; Robert Mullins; Val C. Sheffield
Tags: bardet-biedl syndrome, electroretinography, mice, obesity, retinal degeneration
Investigative Ophthalmology & Visual Science January 2012, Vol.53, 100-106. doi:https://doi.org/10.1167/iovs.11-8544
Frequency and Amplitude Modulation Have Different Effects on the Percepts Elicited by Retinal Stimulation Free
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Devyani Nanduri; Ione Fine; Alan Horsager; Geoffrey M. Boynton; Mark S. Humayun; Robert J. Greenberg; James D. Weiland
Tags: accommodation phosphene
Investigative Ophthalmology & Visual Science January 2012, Vol.53, 205-214. doi:https://doi.org/10.1167/iovs.11-8401

Visual Neuroscience

Diffusion Tensor Imaging Detected Optic Nerve Injury Correlates with Decreased Compound Action Potentials after Murine Retinal Ischemia Free
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Qing Wang; Roman Vlkolinsky; Mingqiang Xie; Andre Obenaus; Sheng-Kwei Song
Tags: action potentials, diffusion tensor imaging, myelin, optic nerve, optic nerve injuries
Investigative Ophthalmology & Visual Science January 2012, Vol.53, 136-142. doi:https://doi.org/10.1167/iovs.11-7908

Visual Psychophysics and Physiological Optics

The Accommodative Lag of the Young Hyperopic Patient Free
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T. Rowan Candy; Kathryn H. Gray; Christy C. Hohenbary; Don W. Lyon
Tags: amblyopia, astigmatism, child, cycloplegics, eye
Investigative Ophthalmology & Visual Science January 2012, Vol.53, 143-149. doi:https://doi.org/10.1167/iovs.11-8174
Full-Field Accommodation in Rhesus Monkeys Measured Using Infrared Photorefraction Free
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Lin He; Mark Wendt; Adrian Glasser
Tags: refraction, visual accommodation, macaca mulatta, calibration
Investigative Ophthalmology & Visual Science January 2012, Vol.53, 215-223. doi:https://doi.org/10.1167/iovs.11-8324
Protective Effects of High Ambient Lighting on the Development of Form-Deprivation Myopia in Rhesus Monkeys Free
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Earl L. Smith, III; Li-Fang Hung; Juan Huang
Tags: cercopithecidae, lighting, macaca mulatta, myopia, eye
Investigative Ophthalmology & Visual Science January 2012, Vol.53, 421-428. doi:https://doi.org/10.1167/iovs.11-8652

Clinical Trials

Validated Automatic Segmentation of AMD Pathology Including Drusen and Geographic Atrophy in SD-OCT Images Free
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Stephanie J. Chiu; Joseph A. Izatt; Rachelle V. O'Connell; Katrina P. Winter; Cynthia A. Toth; Sina Farsiu
Tags: atrophy, drusen, pathology, eye, volume
Investigative Ophthalmology & Visual Science January 2012, Vol.53, 53-61. doi:https://doi.org/10.1167/iovs.11-7640
The Rate of Visual Field Change in the Ocular Hypertension Treatment Study Free
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Shaban Demirel; Carlos Gustavo V. De Moraes; Stuart K. Gardiner; Jeffrey M. Liebmann; George A. Cioffi; Robert Ritch; Mae O. Gordon; Michael A. Kass; for the Ocular Hypertension Treatment Study
Tags: eye, ocular hypertension, open-angle glaucoma, visual fields, optic disk
Investigative Ophthalmology & Visual Science January 2012, Vol.53, 224-227. doi:https://doi.org/10.1167/iovs.10-7117
Pseudomonas aeruginosa Keratitis: Outcomes and Response to Corticosteroid Treatment Free
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Aileen Sy; Muthiah Srinivasan; Jeena Mascarenhas; Prajna Lalitha; Revathi Rajaraman; Meenakshi Ravindran; Catherine E. Oldenburg; Kathryn J. Ray; David Glidden; Michael E. Zegans; Stephen D. McLeod; Thomas M. Lietman; Nisha R. Acharya
Tags: adrenal corticosteroids, glucocorticoids, keratitis, mineralocorticoids, pseudomonas aeruginosa
Investigative Ophthalmology & Visual Science January 2012, Vol.53, 267-272. doi:https://doi.org/10.1167/iovs.11-7840
Effect of Nifedipine on Choroidal Blood Flow Regulation during Isometric Exercise Free
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Doreen Schmidl; Ana Prinz; Julia Kolodjaschna; Elzbieta Polska; Alexandra Luksch; Gabriele Fuchsjager-Mayrl; Gerhard Garhofer; Leopold Schmetterer
Tags: exercise, isometric, nifedipine, regulation, vascular flow, placebos
Investigative Ophthalmology & Visual Science January 2012, Vol.53, 374-378. doi:https://doi.org/10.1167/iovs.11-8536

Letters to the Editor

Elastic Modulus Determination of Normal and Glaucomatous Human Trabecular Meshwork Free
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Paul Russell; Mark Johnson
Tags: glaucoma, trabecular meshwork
Investigative Ophthalmology & Visual Science January 2012, Vol.53, 117. doi:https://doi.org/10.1167/iovs.11-9314
Author Response: On Alternative Methods for Measuring Visual Field Decay: Tobit Linear Regression Free
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Joseph Caprioli; Dennis Mock; Elena Bitrian; Abdelmonem Afifi; Fei Yu; Kouros Nouri-Mahdavi; Anne Coleman
Tags: linear regression, visual fields
Investigative Ophthalmology & Visual Science January 2012, Vol.53, 118. doi:https://doi.org/10.1167/iovs.11-9240
Author Response: Incident Open-Angle Glaucoma and Ocular Perfusion Pressure Free
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Wishal D. Ramdas; Roger C. W. Wolfs; Albert Hofman; Paulus T. V. M. de Jong; Johannes R. Vingerling; Nomdo M. Jansonius
Tags: open-angle glaucoma, perfusion
Investigative Ophthalmology & Visual Science January 2012, Vol.53, 150-151. doi:https://doi.org/10.1167/iovs.11-8913

Erratum

Erratum Free
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Investigative Ophthalmology & Visual Science January 2012, Vol.53, 119. doi:https://doi.org/10.1167/iovs.10-5688a
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