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Research Highlight

A Significant Advance in the Biomechanical Evaluation of the Optic Nerve Head Free
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Thao D. Nguyen
Investigative Ophthalmology & Visual Science January 2014, Vol.55, 215. doi:10.1167/iovs.13-13789
Toward an Improved Understanding of the Physiology of Aqueous Humor Flow Free
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J. Cameron Millar
Investigative Ophthalmology & Visual Science January 2014, Vol.55, 404. doi:10.1167/iovs.13-13753

Anatomy and Pathology/Oncology

Enzymatic Degradation Identifies Components Responsible for the Structural Properties of the Vitreous Body Free
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Benjamen A. Filas; Qianru Zhang; Ruth J. Okamoto; Ying-Bo Shui; David C. Beebe
Tags: vitreous body, catabolism
Investigative Ophthalmology & Visual Science January 2014, Vol.55, 55-63. doi:10.1167/iovs.13-13026
Ocular Changes in TgF344-AD Rat Model of Alzheimer's Disease Free
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Yuchun Tsai; Bin Lu; Alexander V. Ljubimov; Sergey Girman; Fred N. Ross-Cisneros; Alfredo A. Sadun; Clive N. Svendsen; Robert M. Cohen; Shaomei Wang
Tags: alzheimer's disease, antibodies, choroid, eye, rats
Investigative Ophthalmology & Visual Science January 2014, Vol.55, 523-534. doi:10.1167/iovs.13-12888

Biochemistry and Molecular Biology

Biophysical and Morphological Evaluation of Human Normal and Dry Eye Meibum Using Hot Stage Polarized Light Microscopy Free
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Igor A. Butovich; Hua Lu; Anne McMahon; Howard Ketelson; Michelle Senchyna; David Meadows; Elaine Campbell; Mike Molai; Emily Linsenbardt
Tags: birefringence, dry eye syndromes, lipids, proteins, temperature
Investigative Ophthalmology & Visual Science January 2014, Vol.55, 87-101. doi:10.1167/iovs.13-13355
Effect of Nerve Growth Factor on the In Vitro Induction of Apoptosis of Human Conjunctival Epithelial Cells by Hyperosmolar Stress Free
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Soon-Suk Kang; Sae-Jin Ha; Eun-Soon Kim; Jin-A Shin; Jae Yong Kim; Hungwon Tchah
Tags: apoptosis, conjunctival epithelial cells, hyperosmolality, hyperosmolar hyperglycemia, nerve growth factors
Investigative Ophthalmology & Visual Science January 2014, Vol.55, 535-541. doi:10.1167/iovs.13-12459

Clinical and Epidemiologic Research

Corneal Biomechanical Properties and Glaucoma-Related Quantitative Traits in the EPIC-Norfolk Eye Study Free
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Anthony P. Khawaja; Michelle P. Y. Chan; David C. Broadway; David F. Garway-Heath; Robert Luben; Jennifer L. Y. Yip; Shabina Hayat; Kay-Tee Khaw; Paul J. Foster
Tags: cornea, corneal hysteresis, eye, glaucoma, retinal nerve fiber layer
Investigative Ophthalmology & Visual Science January 2014, Vol.55, 117-124. doi:10.1167/iovs.13-13290
Accuracy of Rural Refractionists in Western China Free
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Zhongqiang Zhou; Junxia Zeng; Xiaochen Ma; Xiaopeng Pang; Hongmei Yi; Qianyun Chen; Mirjam E. Meltzer; Mingguang He; Scott Rozelle; Nathan Congdon
Tags: child, china, eye, refraction, refractive errors
Investigative Ophthalmology & Visual Science January 2014, Vol.55, 154-161. doi:10.1167/iovs.13-13250
Reduced Fluorescein Angiography and Fundus Photography Use in the Management of Neovascular Macular Degeneration and Macular Edema During the Past Decade Free
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Eric W. Schneider; Prithvi Mruthyunjaya; Nidhi Talwar; Kristen Harris Nwanyanwu; Bin Nan; Joshua D. Stein
Tags: diagnostic imaging, diagnostic techniques and procedures, edema, fluorescein angiography, fundus photography
Investigative Ophthalmology & Visual Science January 2014, Vol.55, 542-549. doi:10.1167/iovs.13-13034
Subfoveal Choroidal Thickness in 1323 Children Aged 11 to 12 Years and Association With Puberty: The Copenhagen Child Cohort 2000 Eye Study Free