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Anatomy and Pathology/Oncology

Polyol Metabolism of Retrograde Axonal Transport in Diabetic Rat Large Optic Nerve Fiber Free
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Masanori Ino-ue; Lixin Zhang; Hiroaki Naka; Hiroshi Kuriyama; Misao Yamamoto
Tags: axonal transport, diabetes mellitus, optic nerve, metabolism
Investigative Ophthalmology & Visual Science December 2000, Vol.41, 4055-4058. doi:

Biochemistry and Molecular Biology

The Human cGMP-PDE β-Subunit Promoter Region Directs Expression of the Gene to Mouse Photoreceptors Free
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Sandra B. Ogueta; Adriana Di Polo; John G. Flannery; Clyde K. Yamashita; Debora B. Farber
Tags: cyclic gmp, galactosidase, genes, mice, mice, transgenic
Investigative Ophthalmology & Visual Science December 2000, Vol.41, 4059-4063. doi:
Polymorphisms of the Aldose Reductase Gene and Susceptibility to Retinopathy in Type 1 Diabetes Mellitus Free
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Andrew Demaine; Deborah Cross; Ann Millward
Tags: aldehyde reductase, diabetic retinopathy, disease susceptibility, genes, polymorphism
Investigative Ophthalmology & Visual Science December 2000, Vol.41, 4064-4068. doi:
RP1 Protein Truncating Mutations Predominate at the RP1 adRP Locus Free
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Annette Payne; Eranga Vithana; Shagufta Khaliq; Abdul Hameed; Jane Deller; Leen Abu-Safieh; Sana Kermani; Bart P. Leroy; S. Qasim Mehdi; Anthony T. Moore; Alan C. Bird; Shomi S. Bhattacharya
Tags: mutation, proteins, family
Investigative Ophthalmology & Visual Science December 2000, Vol.41, 4069-4073. doi:

Clinical and Epidemiologic Research

Operational Comparison of Single-Dose Azithromycin and Topical Tetracycline for Trachoma Free
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Richard J. C. Bowman; Ansumana Sillah; Carlijn van Dehn; Victoria M. Goode; Mahiul Muquit; Gordon J. Johnson; Paul Milligan; Jane Rowley; Hannah Faal; Robin L. Bailey
Tags: azithromycin, single-dose regimen, tetracycline, trachoma
Investigative Ophthalmology & Visual Science December 2000, Vol.41, 4074-4079. doi:

Cornea

C57BL/6 Mice Lacking Muc1 Show No Ocular Surface Phenotype Free
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Yukitaka Danjo; Linda D. Hazlett; Ilene K. Gipson
Tags: mice, mice, inbred c57bl, mice, knockout, phenotype, bacterial adhesion
Investigative Ophthalmology & Visual Science December 2000, Vol.41, 4080-4084. doi:
Corneal Endothelial Cell Survival in Organ Cultures under Acute Oxidative Stress: Effect of VIP Free
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Shay-Whey M. Koh; James A. Waschek
Tags: cattle, cornea, corneal endothelium, endothelial cells, eye
Investigative Ophthalmology & Visual Science December 2000, Vol.41, 4085-4092. doi:
Corneal Epithelial Tight Junctions and Their Response to Lipopolysaccharide Challenge Free
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Xian-jin Yi; Yuan Wang; Fu-Shin X. Yu
Tags: cornea, corneal epithelial cells, epithelium, lipopolysaccharides, proteins
Investigative Ophthalmology & Visual Science December 2000, Vol.41, 4093-4100. doi:
Developmental Changes in Patterns of Expression of Tenascin-C Variants in the Human Cornea Free
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Henry Maseruka; Alan Ridgway; Andrew Tullo; Richard Bonshek
Tags: adult, child, cornea, newborn, tenascin
Investigative Ophthalmology & Visual Science December 2000, Vol.41, 4101-4107. doi:
Measurement of mRNAs for TGFβ and Extracellular Matrix Proteins in Corneas of Rats after PRK Free
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Cui Chen; Beatrice Michelini–Norris; Scott Stevens; James Rowsey; Xiao-ou Ren; Michael Goldstein; Gregory Schultz
Tags: cornea, extracellular matrix proteins, rna, rna, messenger, rats
Investigative Ophthalmology & Visual Science December 2000, Vol.41, 4108-4116. doi:
Optical and Visual Impact of Tear Break-up in Human Eyes Free
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Ron Tutt; Arthur Bradley; Carolyn Begley; Larry N. Thibos
Tags: eye, image quality, optics, tear film finding
Investigative Ophthalmology & Visual Science December 2000, Vol.41, 4117-4123. doi:
Protein Kinase C Regulation of Corneal Endothelial Cell Proliferation and Cell Cycle Free
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Melanie A. Graham; Ian Rawe; Darlene A. Dartt; Nancy C. Joyce
Tags: cell cycle, cell proliferation, cornea, endothelial cells, protein isoforms
Investigative Ophthalmology & Visual Science December 2000, Vol.41, 4124-4132. doi:
Regulation of Human Corneal Epithelial Cell Proliferation and Apoptosis by Dexamethasone Free
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Tristan Bourcier; Patricia Forgez; Vincent Borderie; Sarah Scheer; William Rostène; Laurent Laroche
Tags: apoptosis, corneal epithelial cells, dexamethasone, epithelial cells, regulation
Investigative Ophthalmology & Visual Science December 2000, Vol.41, 4133-4141. doi:
Differential Expression of Matrix Metalloproteinases and Their Tissue Inhibitors at the Advancing Pterygium Head Free
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Nick Di Girolamo; Denis Wakefield; Minas T. Coroneo
Tags: matrix metalloproteinases, pterygium, body tissue
Investigative Ophthalmology & Visual Science December 2000, Vol.41, 4142-4149. doi:

Glaucoma

Comparison of Conventional and Pattern Discrimination Perimetry in a Prospective Study of Glaucoma Patients Free
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Irfan Ansari; Balwantray C. Chauhan; Terry A. McCormick; Raymond P. LeBlanc
Tags: glaucoma, perimetry, prospective studies, visual fields
Investigative Ophthalmology & Visual Science December 2000, Vol.41, 4150-4157. doi:
Enhanced Short-Term Plasmid Transfection of Filtration Surgery Tissues Free
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Guy J. Angella; Mark B. Sherwood; Lakshmi Balasubramanian; J. William Doyle; Mary F. Smith; Gysbert van Setten; Michael Goldstein; Gregory S. Schultz
Tags: body tissue, chloramphenicol o-acetyltransferase, filtering surgery, plasmids, transfection
Investigative Ophthalmology & Visual Science December 2000, Vol.41, 4158-4162. doi:
Recombinant TIGR/MYOC Increases Outflow Resistance in the Human Anterior Segment Free
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Michael P. Fautsch; Cindy K. Bahler; David J. Jewison; Douglas H. Johnson
Tags: myoc gene, proteins
Investigative Ophthalmology & Visual Science December 2000, Vol.41, 4163-4168. doi:
RGC Death in Mice after Optic Nerve Crush Injury: Oxidative Stress and Neuroprotection Free
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Hana Levkovitch–Verbin; Cathy Harris–Cerruti; Yoram Groner; Larry A. Wheeler; Michal Schwartz; Eti Yoles
Tags: crushing injuries, mice, neuroprotection, optic nerve, oxidative stress
Investigative Ophthalmology & Visual Science December 2000, Vol.41, 4169-4174. doi:

Immunology and Microbiology

Growth Factors and Collagen Distribution in Vernal Keratoconjunctivitis Free
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Andrea Leonardi; Paola Brun; Marco Tavolato; Giovanni Abatangelo; Mario Plebani; Antonio G. Secchi
Tags: body tissue, collagen, growth factor, keratoconjunctivitis, vernal, platelet-derived growth factor
Investigative Ophthalmology & Visual Science December 2000, Vol.41, 4175-4181. doi:
Induction of Experimental Autoimmune Keratitis by Adoptive Transfer of Human Corneal Antigen–Specific T-Cell Line Free
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Esen Karamursel Akpek; Sammy H. Liu; John D. Gottsch
Tags: adoptive transfer, antigens, autoimmune diseases, autoimmunity, cornea
Investigative Ophthalmology & Visual Science December 2000, Vol.41, 4182-4188. doi:
Membrane-Type Matrix Metalloproteinases in Mice Intracorneally Infected with Pseudomonas aeruginosa Free
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Zhong Dong; Moshira Ghabrial; Malkhan Katar; Rafael Fridman; Richard S. Berk
Tags: cornea, matrix metalloproteinases, mice, pseudomonas aeruginosa, tissue membrane
Investigative Ophthalmology & Visual Science December 2000, Vol.41, 4189-4194. doi:
Complement Regulatory Activity of Normal Human Intraocular Fluid Is Mediated by MCP, DAF, and CD59 Free
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Jeong-Hyeon Sohn; Henry J. Kaplan; Hye-Jung Suk; Puran S. Bora; Nalini S. Bora
Tags: antigens, cd59, aqueous humor, complement system proteins, vitreous body
Investigative Ophthalmology & Visual Science December 2000, Vol.41, 4195-4202. doi:
Interleukin-1 Receptor Antagonist Therapy and Induction of Anterior Chamber–Associated Immune Deviation–Type Tolerance after Corneal Transplantation Free
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Jun Yamada; Su-Ning Zhu; J. Wayne Streilein; M. Reza Dana
Tags: anterior chamber of eye, antigens, eye, interleukin-1 receptor antagonists, keratoplasty
Investigative Ophthalmology & Visual Science December 2000, Vol.41, 4203-4208. doi:
Preventive Effect of Local Plasmid DNA Vaccine Encoding gD or gD-IL-2 on Herpetic Keratitis Free
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Tomoyuki Inoue; Yoshitsugu Inoue; Takao Nakamura; Atsushi Yoshida; Kenichiro Takahashi; Yumiko Inoue; Yoshikazu Shimomura; Yasuo Tano; Yukio Fujisawa; Aki Aono; Kozaburo Hayashi
Tags: gadolinium, grenada, immunization, keratitis, herpetic, mice
Investigative Ophthalmology & Visual Science December 2000, Vol.41, 4209-4215. doi:

Lens

Hepatocyte Growth Factor Function and c-Met Expression in Human Lens Epithelial Cells Free
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I. Michael Wormstone; Shigeo Tamiya; Julia M. Marcantonio; John R. Reddan
Tags: hepatocyte growth factor, lens, crystalline, met gene, epithelial cells
Investigative Ophthalmology & Visual Science December 2000, Vol.41, 4216-4222. doi:
Induction of Cell Cycle Entry and Cell Death in Postmitotic Lens Fiber Cells by Overexpression of E2F1 or E2F2 Free
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Qin Chen; Fang-Cheng Hung; Larry Fromm; Paul A. Overbeek
Tags: cell cycle, lens (device), lens, crystalline, cell death, protein overexpression
Investigative Ophthalmology & Visual Science December 2000, Vol.41, 4223-4231. doi:
Influence of Specific Regions in Lp82 Calpain on Protein Stability, Activity, and Localization within Lens Free
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Hong Ma; Marjorie Shih; Chiho Fukiage; Mitsuyoshi Azuma; Melinda K. Duncan; Nathan A. Reed; Isabelle Richard; Jacques S. Beckmann; Thomas R. Shearer
Tags: calpain, lens (device), lens, crystalline, proteins
Investigative Ophthalmology & Visual Science December 2000, Vol.41, 4232-4239. doi:

Physiology and Pharmacology

Mediation of Calcium-Independent Contraction in Trabecular Meshwork through Protein Kinase C and Rho-A Free
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Hagen Thieme; Michael Nuskovski; Jens Uwe Nass; Uwe Pleyer; Olaf Strauss; Michael Wiederholt
Tags: calcium, protein kinase c, trabecular meshwork, immunoprecipitation, western blotting
Investigative Ophthalmology & Visual Science December 2000, Vol.41, 4240-4246. doi:
Chloride Channel Expression in Cultured Human Fetal RPE Cells: Response to Oxidative Stress Free
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Nancy K. Wills; Tianxiang Weng; Lijun Mo; Helen L. Hellmich; Alan Yu; Ting Wang; Sarah Buchheit; Bernard F. Godley
Tags: chloride channels, chlorides, fetus, retinal pigment cell, oxidative stress
Investigative Ophthalmology & Visual Science December 2000, Vol.41, 4247-4255. doi:
Effect of VEGF on Retinal Microvascular Endothelial Hydraulic Conductivity: The Role of NO Free
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Sunitha Lakshminarayanan; David A. Antonetti; Thomas W. Gardner; John M. Tarbell
Tags: vascular endothelial growth factor a, endothelium
Investigative Ophthalmology & Visual Science December 2000, Vol.41, 4256-4261. doi:
Involvement of Calcium-Activated Potassium Channels in the Regulation of DNA Synthesis in Cultured Müller Glial Cells Free
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Hannes Kodal; Michael Weick; Vanessa Moll; Bernd Biedermann; Andreas Reichenbach; Andreas Bringmann
Tags: calcium-activated potassium channel, dna chemical synthesis, neuroglia, regulation, mass or substance concentration per volume
Investigative Ophthalmology & Visual Science December 2000, Vol.41, 4262-4267. doi:

Retina

Incorporation and Differentiation of Hippocampus-Derived Neural Stem Cells Transplanted in Injured Adult Rat Retina Free
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Akihiro Nishida; Masayo Takahashi; Hidenobu Tanihara; Ichiro Nakano; Jun B. Takahashi; Akira Mizoguchi; Chizuka Ide; Yoshihito Honda
Tags: adult, hippocampus, neural stem cells, retina, transplantation
Investigative Ophthalmology & Visual Science December 2000, Vol.41, 4268-4274. doi:
A Novel Model of Retinopathy of Prematurity Simulating Preterm Oxygen Variability in the Rat Free
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Steve Cunningham; Janet R. McColm; Jean Wade; Kofi Sedowofia; Neil McIntosh; Brian Fleck
Tags: oxygen, retinopathy of prematurity, vascular endothelial growth factor a, blood capillaries, retina
Investigative Ophthalmology & Visual Science December 2000, Vol.41, 4275-4280. doi:
Tetracycline-Inducible System for Photoreceptor-Specific Gene Expression Free
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Michelle A. Chang; James W. Horner; Bruce R. Conklin; Ronald A. DePinho; Dean Bok; Donald J. Zack
Tags: animals, transgenic, doxycycline, gene expression, opsin, photoreceptors
Investigative Ophthalmology & Visual Science December 2000, Vol.41, 4281-4287. doi:
Retinal Changes after Retinal Translocation Surgery with Scleral Imbrication in Dog Eyes Free
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Atsushi Hayashi; Shinichi Usui; Kiyotomi Kawaguchi; Sayuri Fujioka; Shunji Kusaka; Takashi Fujikado; Masahito Ohji; Yasuo Tano
Tags: dog, domestic, eye, sclera, surgical procedures, operative, translocation (genetics)
Investigative Ophthalmology & Visual Science December 2000, Vol.41, 4288-4292. doi:
Genetics and Phenotypes of RPE65 Mutations in Inherited Retinal Degeneration Free
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Debra A. Thompson; Péter Gyürüs; Laura L. Fleischer; Eve L. Bingham; Christina L. McHenry; Eckart Apfelstedt–Sylla; Eberhart Zrenner; Birgit Lorenz; Julia E. Richards; Samuel G. Jacobson; Paul A. Sieving; Andreas Gal
Tags: mutation, phenotype, retinal degeneration, genetics
Investigative Ophthalmology & Visual Science December 2000, Vol.41, 4293-4299. doi:
Retinal Damage by Air Infusion during Vitrectomy in Rabbit Eyes Free
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Tadashi Hasumura; Naoko Yonemura; Akira Hirata; Yasuhiro Murata; Akira Negi
Tags: eye, infusion procedures, oryctolagus cuniculus, vitrectomy, retina
Investigative Ophthalmology & Visual Science December 2000, Vol.41, 4300-4304. doi:
Ultrastructural Changes Associated with Accumulation of Inclusion Bodies in Rat Retinal Pigment Epithelium Free
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Akiko Okubo; Munefumi Sameshima; Kazuhiko Unoki; Fumiyuki Uehara; Alan C. Bird
Tags: eye, inclusion bodies, injections, phagosomes, photoreceptors
Investigative Ophthalmology & Visual Science December 2000, Vol.41, 4305-4312. doi:

Retinal Cell Biology

Ganglion Cell Loss after Optic Nerve Crush Mediated through AMPA-Kainate and NMDA Receptors Free
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Frank Schuettauf; Rita Naskar; Christian K. Vorwerk; David Zurakowski; Evan B. Dreyer
Tags: alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid, ganglia, n-methyl-d-aspartate receptors, optic nerve
Investigative Ophthalmology & Visual Science December 2000, Vol.41, 4313-4316. doi:
Green Cone Opsin and Rhodopsin Regulation by CNTF and Staurosporine in Cultured Chick Photoreceptors Free
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Han-Qing Xie; Ruben Adler
Tags: ciliary neurotrophic factor, opsin, photoreceptors, retinal cone, rhodopsin
Investigative Ophthalmology & Visual Science December 2000, Vol.41, 4317-4323. doi:
Promotion of Adhesion and Migration of RPE Cells to Provisional Extracellular Matrices by TNF-α Free
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ManLin Jin; Shikun He; Vanessa Wörpel; Stephen J. Ryan; David R. Hinton
Tags: adhesions, retinal pigment cell, tumor necrosis factors, integrins, fibronectins
Investigative Ophthalmology & Visual Science December 2000, Vol.41, 4324-4332. doi:
Expression Pattern of the Ocular Albinism Type 1 (Oa1) Gene in the Murine Retinal Pigment Epithelium Free
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Enrico M. Surace; Barbara Angeletti; Andrea Ballabio; Valeria Marigo
Tags: albinism, ocular, genes, retinal pigment epithelium, eye, in situ hybridization
Investigative Ophthalmology & Visual Science December 2000, Vol.41, 4333-4337. doi:
Neuroglycan C, a Neural Tissue–Specific Transmembrane Chondroitin Sulfate Proteoglycan, in Retinal Neural Network Formation Free
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Masaru Inatani; Hidenobu Tanihara; Atsuhiko Oohira; Yasumasa Otori; Akihiro Nishida; Megumi Honjo; Noriaki Kido; Yoshihito Honda
Tags: chondroitin sulfates, nerve tissue, proteins, proteoglycan, retina
Investigative Ophthalmology & Visual Science December 2000, Vol.41, 4338-4346. doi:

Visual Psychophysics and Physiological Optics

Rod-Mediated Increment Threshold Functions in Infants Free
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Ronald M. Hansen; Anne B. Fulton
Tags: infant, rod photoreceptors, parafoveal region
Investigative Ophthalmology & Visual Science December 2000, Vol.41, 4347-4352. doi:

In-Brief

Lighting the Way to Better Ocular Therapies Free
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Tags: lighting, oxygen, complement system proteins, trachoma, azithromycin
Investigative Ophthalmology & Visual Science December 2000, Vol.41, f4-F5. doi:

Other

Reviewers Free
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Tags: betula, calculi, christianity, patients' rooms, subacute sclerosing panencephalitis
Investigative Ophthalmology & Visual Science December 2000, Vol.41, 4353-4358. doi:
Copyright © 2025 Association for Research in Vision and Ophthalmology.
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