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Anatomy and Pathology/Oncology

Age-Dependent Changes in the Basal Retinovitreous Adhesion Free
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Jing Wang; David McLeod; David B. Henson; Paul N. Bishop
Tags: adhesions, eye, vitreous body, donors, retina
Investigative Ophthalmology & Visual Science May 2003, Vol.44, 1793-1800. doi:https://doi.org/10.1167/iovs.02-0802
EMAP-II Expression Is Associated with Macrophage Accumulation in Primary Uveal Melanoma Free
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Ruud Clarijs; Lia Schalkwijk; Dirk J. Ruiter; Robert M. W. de Waal
Tags: macrophages, neoplasms, uveal melanoma, immunohistochemistry, tumor cells
Investigative Ophthalmology & Visual Science May 2003, Vol.44, 1801-1806. doi:https://doi.org/10.1167/iovs.02-0624
Characterization of Mucins in Human Lacrimal Sac and Nasolacrimal Duct Free
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Friedrich P. Paulsen; Anthony P. Corfield; Margitta Hinz; Werner Hoffmann; Ulrich Schaudig; Andreas B. Thale; Monica Berry
Tags: mucins, nasolacrimal duct, lacrimal duct, immunohistochemistry
Investigative Ophthalmology & Visual Science May 2003, Vol.44, 1807-1813. doi:https://doi.org/10.1167/iovs.02-0744

Biochemistry and Molecular Biology

Expression and Localization of Tenomodulin, a Transmembrane Type Chondromodulin-I-Related Angiogenesis Inhibitor, in Mouse Eyes Free
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Yusuke Oshima; Chisa Shukunami; Junichi Honda; Koji Nishida; Fumi Tashiro; Jun-ichi Miyazaki; Yuji Hiraki; Yasuo Tano
Tags: adenoviruses, angiogenesis inhibitors, choroideremia, eye, in situ hybridization
Investigative Ophthalmology & Visual Science May 2003, Vol.44, 1814-1823. doi:https://doi.org/10.1167/iovs.02-0664
Analysis of the Frequent R1141X Mutation in the ABCC6 Gene in Pseudoxanthoma Elasticum Free
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Xiaofeng Hu; Ron Peek; Astrid Plomp; Jacoline ten Brink; George Scheffer; Simone van Soest; Anita Leys; Paulus T. V. M. de Jong; Arthur A. B. Bergen
Tags: abcc6 gene, mutation, pseudoxanthoma elasticum
Investigative Ophthalmology & Visual Science May 2003, Vol.44, 1824-1829. doi:https://doi.org/10.1167/iovs.02-0981
New Locus for Autosomal Dominant High Myopia Maps to the Long Arm of Chromosome 17 Free
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Prasuna Paluru; Shawn M. Ronan; Elise Heon; Marcella Devoto; Scott C. Wildenberg; Genaro Scavello; Ann Holleschau; Outi Mäkitie; William G. Cole; Richard A. King; Terri L. Young
Tags: arm of chromosome, myopia, maps
Investigative Ophthalmology & Visual Science May 2003, Vol.44, 1830-1836. doi:https://doi.org/10.1167/iovs.02-0697

Cornea

Corneal Transduction to Inhibit Angiogenesis and Graft Failure Free
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Raghu C. Murthy; Trevor J. McFarland; Jon Yoken; Sandy Chen; Chris Barone; Dorthea Burke; Yi Zhang; Binoy Appukuttan; J. Timothy Stout
Tags: angiogenesis, cornea, tissue transplants, neovascularization, pathologic, keratoplasty
Investigative Ophthalmology & Visual Science May 2003, Vol.44, 1837-1842. doi:https://doi.org/10.1167/iovs.02-0853
Effects of Eyelid Closure and Disposable and Silicone Hydrogel Extended Contact Lens Wear on Rabbit Corneal Epithelial Proliferation Free
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Patrick M. Ladage; David H. Ren; W. Matthew Petroll; James V. Jester; Jan P. G. Bergmanson; H. Dwight Cavanagh
Tags: contact lenses, cornea, epithelium, eyelid, hydrogel
Investigative Ophthalmology & Visual Science May 2003, Vol.44, 1843-1849. doi:https://doi.org/10.1167/iovs.02-0897
Myofibroblast Differentiation of Normal Human Keratocytes and hTERT, Extended-Life Human Corneal Fibroblasts Free
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James V. Jester; Jiying Huang; Stephen Fisher; Jennifer Spiekerman; Jin Ho Chang; Woodring E. Wright; Jerry W. Shay
Tags: cornea, fibroblasts, keratocytes, myofibroblasts, karyotype determination procedure
Investigative Ophthalmology & Visual Science May 2003, Vol.44, 1850-1858. doi:https://doi.org/10.1167/iovs.02-0973
Defensin Expression by the Cornea: Multiple Signalling Pathways Mediate IL-1β Stimulation of hBD-2 Expression by Human Corneal Epithelial Cells Free
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Alison M. McDermott; Rachel L. Redfern; Bei Zhang; Ying Pei; Ling Huang; Rita J. Proske
Tags: cornea, corneal epithelial cells, cytokine, defb4 gene, defensins
Investigative Ophthalmology & Visual Science May 2003, Vol.44, 1859-1865. doi:https://doi.org/10.1167/iovs.02-0787
Antioxidant Protection against Corneal Damage by Free Radicals during Phacoemulsification Free
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Alexander Rubowitz; Ehud I. Assia; Mordechai Rosner; Morris Topaz
Tags: antioxidants, cornea, free radicals, phacoemulsification, ascorbic acid
Investigative Ophthalmology & Visual Science May 2003, Vol.44, 1866-1870. doi:https://doi.org/10.1167/iovs.02-0892
Corneal Abnormalities in Pax6 +/− Small Eye Mice Mimic Human Aniridia-Related Keratopathy Free
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Thaya Ramaesh; J. Martin Collinson; Kanna Ramaesh; Matthew H. Kaufman; John D. West; Baljean Dhillon
Tags: aniridia, cornea, eye, mice
Investigative Ophthalmology & Visual Science May 2003, Vol.44, 1871-1878. doi:https://doi.org/10.1167/iovs.02-0576
Connective Tissue Growth Factor Expression and Action in Human Corneal Fibroblast Cultures and Rat Corneas after Photorefractive Keratectomy Free
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Timothy D. Blalock; Matthew R. Duncan; Juan C. Varela; Michael H. Goldstein; Sonal S. Tuli; Gary R. Grotendorst; Gregory S. Schultz
Tags: connective tissue growth factor, cornea, fibroblasts, proteins
Investigative Ophthalmology & Visual Science May 2003, Vol.44, 1879-1887. doi:https://doi.org/10.1167/iovs.02-0860
Periductal Area as the Primary Site for T-Cell Activation in Lacrimal Gland Chronic Graft-Versus-Host Disease Free
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Yoko Ogawa; Masataka Kuwana; Kazuto Yamazaki; Yukihiko Mashima; Masakazu Yamada; Takehiko Mori; Shinichiro Okamoto; Yoshihisa Oguchi; Yutaka Kawakami
Tags: graft-versus-host disease, chronic, hla-dr antigens, intercellular adhesion molecule 1, lacrimal gland, t-cell activation
Investigative Ophthalmology & Visual Science May 2003, Vol.44, 1888-1896. doi:https://doi.org/10.1167/iovs.02-0699
Kinetic Analysis of Tear Interference Images in Aqueous Tear Deficiency Dry Eye before and after Punctal Occlusion Free
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Eiki Goto; Scheffer C. G. Tseng
Tags: dry eye syndromes, kinetics, lipids, eye, cornea
Investigative Ophthalmology & Visual Science May 2003, Vol.44, 1897-1905. doi:https://doi.org/10.1167/iovs.02-0818
Annulus of Collagen Fibrils in Mouse Cornea and Structural Matrix Alterations in a Murine-Specific Keratopathy Free
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Andrew J. Quantock; Sally Dennis; Wakako Adachi; Shigeru Kinoshita; Craig Boote; Keith M. Meek; Yoshibumi Matsushima; Masayoshi Tachibana
Tags: collagen, cornea, diagnostic radiologic examination, fibril, mice
Investigative Ophthalmology & Visual Science May 2003, Vol.44, 1906-1911. doi:https://doi.org/10.1167/iovs.02-0884
Apoptosis in Keratocytes Caused by Mitomycin C Free
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Tae-im Kim; Hungwon Tchah; Seung-ah Lee; Kyungrim Sung; Beom Jin Cho; Michael S. Kook
Tags: apoptosis, keratocytes, mitomycin
Investigative Ophthalmology & Visual Science May 2003, Vol.44, 1912-1917. doi:https://doi.org/10.1167/iovs.02-0977

Eye Movements, Strabismus, Amblyopia and Neuro-ophthalmology

Molecular Organization of the Extraocular Muscle Neuromuscular Junction: Partial Conservation of and Divergence from the Skeletal Muscle Prototype Free
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Sangeeta Khanna; Chelliah R. Richmonds; Henry J. Kaminski; John D. Porter
Tags: agrin, dystrophin-associated glycoprotein complex, muscle, muscle of orbit, neuregulins
Investigative Ophthalmology & Visual Science May 2003, Vol.44, 1918-1926. doi:https://doi.org/10.1167/iovs.02-0890
Activated Satellite Cells in Extraocular Muscles of Normal Adult Monkeys and Humans Free
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Linda K. McLoon; Jonathan Wirtschafter
Tags: adult, cercopithecidae, muscle of orbit, muscle satellite cell, myogenin
Investigative Ophthalmology & Visual Science May 2003, Vol.44, 1927-1932. doi:https://doi.org/10.1167/iovs.02-0673
Effects of Scleral Search Coil Wear on Visual Function Free
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Elizabeth L. Irving; James E. Zacher; Robert S. Allison; Murchison G. Callender
Tags: eye, sclera, vision, visual acuity, cornea
Investigative Ophthalmology & Visual Science May 2003, Vol.44, 1933-1938. doi:https://doi.org/10.1167/iovs.01-0926
Strabological Findings after Macular Translocation Surgery with 360° Retinotomy Free
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Miho Sato; Hiroko Terasaki; Nobuchika Ogino; Yoko Okamoto; Emi Amano; Kiyoko Ukai; Toshie Hirai
Tags: surgical procedures, operative, translocation (genetics), diplopia
Investigative Ophthalmology & Visual Science May 2003, Vol.44, 1939-1944. doi:https://doi.org/10.1167/iovs.02-0171

Glaucoma

Effects of Prostaglandin Analogues on Human Ciliary Muscle and Trabecular Meshwork Cells Free
PDF
Xiujun Zhao; Keri E. Pearson; Dietrich A. Stephan; Paul Russell
Tags: ciliary muscle, genes, latanoprost, polymerase chain reaction, prostaglandins, synthetic
Investigative Ophthalmology & Visual Science May 2003, Vol.44, 1945-1952. doi:https://doi.org/10.1167/iovs.02-0920
Perfusion with the Olfactomedin Domain of Myocilin Does Not Affect Outflow Facility Free
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Andreas Goldwich; C. Ross Ethier; Darren W.-H. Chan; Ernst R. Tamm
Tags: myoc gene, perfusion, proteins, recombinant proteins
Investigative Ophthalmology & Visual Science May 2003, Vol.44, 1953-1961. doi:https://doi.org/10.1167/iovs.02-0863
Spatial Resolution of the Tendency-Oriented Perimetry Algorithm Free
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Andrew J. Anderson
Tags: perimetry, visual fields
Investigative Ophthalmology & Visual Science May 2003, Vol.44, 1962-1968. doi:https://doi.org/10.1167/iovs.02-0828
Scanning Laser Polarimetry with Variable Corneal Compensation: Identification and Correction for Corneal Birefringence in Eyes with Macular Disease Free
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Harmohina Bagga; David S. Greenfield; Robert W. Knighton
Tags: age-related macular degeneration, birefringence, cornea, eye, macular disorders
Investigative Ophthalmology & Visual Science May 2003, Vol.44, 1969-1976. doi:https://doi.org/10.1167/iovs.02-0923
Ultrasound Activates the TM ELAM-1/IL-1/NF-κB Response: A Potential Mechanism for Intraocular Pressure Reduction after Phacoemulsification Free
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Nan Wang; Shravan K. Chintala; M. Elizabeth Fini; Joel S. Schuman
Tags: e-selectin, interleukin-1, intraocular pressure, phacoemulsification, ultrasonography
Investigative Ophthalmology & Visual Science May 2003, Vol.44, 1977-1981. doi:https://doi.org/10.1167/iovs.02-0631
Retinal Ganglion Cell Protection with Geranylgeranylacetone, a Heat Shock Protein Inducer, in a Rat Glaucoma Model Free
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Yoko Ishii; Jacky M. K. Kwong; Joseph Caprioli
Tags: glaucoma, heat-shock proteins, quercetin, retinal ganglion cells, raised intraocular pressure
Investigative Ophthalmology & Visual Science May 2003, Vol.44, 1982-1992. doi:https://doi.org/10.1167/iovs.02-0912

Immunology and Microbiology

Visualization of Cell Death In Vivo during Murine Endotoxin-Induced Uveitis Free
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Peizeng Yang; Justine R. Smith; K. Sampath Damodar; Stephen R. Planck; James T. Rosenbaum
Tags: cell death, endotoxins, immune reconstitution inflammatory syndrome, iris, uveitis
Investigative Ophthalmology & Visual Science May 2003, Vol.44, 1993-1997. doi:https://doi.org/10.1167/iovs.02-0582
Role of Connective Tissue Growth Factor in the Pathogenesis of Conjunctival Scarring in Ocular Cicatricial Pemphigoid Free
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Mohammed S. Razzaque; C. Stephen Foster; A. Razzaque Ahmed
Tags: collagen type i, conjunctiva, connective tissue growth factor, pathogenesis, fibroblasts
Investigative Ophthalmology & Visual Science May 2003, Vol.44, 1998-2003. doi:https://doi.org/10.1167/iovs.02-0967
Immunohistology of Antigen-Presenting Cells In Vivo: A Novel Method for Serial Observation of Fluorescently Labeled Cells Free
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Matthias D. Becker; Stephen R. Planck; Sergio Crespo; Kiera Garman; Ross J. Fleischman; Per Dullforce; Gregory W. Seitz; Tammy M. Martin; David C. Parker; James T. Rosenbaum
Tags: anterior chamber of eye, antibodies, antigen-presenting cells, immune reconstitution inflammatory syndrome, iris
Investigative Ophthalmology & Visual Science May 2003, Vol.44, 2004-2009. doi:https://doi.org/10.1167/iovs.02-0560
Differential and Cooperative Effects of TNFα, IL-1β, and IFNγ on Human Conjunctival Epithelial Cell Receptor Expression and Chemokine Release Free
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James L. Stahl; Ellen B. Cook; Frank M. Graziano; Neal P. Barney
Tags: chemokines, conjunctival epithelial cells, interleukin-8, rantes, intercellular adhesion molecule 1
Investigative Ophthalmology & Visual Science May 2003, Vol.44, 2010-2015. doi:https://doi.org/10.1167/iovs.02-0721
Expression of Classic and Nonclassic HLA Class I Antigens in Uveal Melanoma Free
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Gerasimos Anastassiou; Vera Rebmann; Stephan Wagner; Norbert Bornfeld; Hans Grosse-Wilde
Tags: histocompatibility antigens class i, hla-a2 antigen, human leukocyte antigens, uveal melanoma, antigens
Investigative Ophthalmology & Visual Science May 2003, Vol.44, 2016-2019. doi:https://doi.org/10.1167/iovs.02-0810
Regulation of MMPs and TIMPs by IL-1β during Corneal Ulceration and Infection Free
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Mei Lang Xue; Denis Wakefield; Mark D. P. Willcox; Andrew R. Lloyd; Nick Di Girolamo; Nerida Cole; Archana Thakur
Tags: antibodies, cornea, corneal ulcer, infections, matrix metalloproteinases
Investigative Ophthalmology & Visual Science May 2003, Vol.44, 2020-2025. doi:https://doi.org/10.1167/iovs.02-0565
Differential Expression of Chemokines by Human Retinal Pigment Epithelial Cells Infected with Cytomegalovirus Free
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Yuko Momma; Chandrasekharam N. Nagineni; Marian S. Chin; Kumar Srinivasan; Barbara Detrick; John J. Hooks
Tags: chemokines, human herpesvirus 5, cytomegalovirus, infections
Investigative Ophthalmology & Visual Science May 2003, Vol.44, 2026-2033. doi:https://doi.org/10.1167/iovs.02-0980

Lens

Alteration of Cadherin in Dexamethasone-Induced Cataract Organ-Cultured Rat Lens Free
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Jungmook Lyu; Jung-A Kim; Sung Kun Chung; Ki-San Kim; Choun-Ki Joo
Tags: cadherins, cataract, dexamethasone, lens (device), lens, crystalline
Investigative Ophthalmology & Visual Science May 2003, Vol.44, 2034-2040. doi:https://doi.org/10.1167/iovs.02-0602
Expression of the Functional Glucocorticoid Receptor in Mouse and Human Lens Epithelial Cells Free
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Vanita Gupta; B. J. Wagner
Tags: epithelial cells, glucocorticoid receptors, lens, crystalline, mice, rna, messenger
Investigative Ophthalmology & Visual Science May 2003, Vol.44, 2041-2046. doi:https://doi.org/10.1167/iovs.02-1091
Vitamin C Metabolomic Mapping in the Lens with 6-Deoxy-6-fluoro-ascorbic Acid and High-Resolution 19F-NMR Spectroscopy Free
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Makoto Satake; Barbara Dmochowska; Yoko Nishikawa; Janusz Madaj; Jie Xue; Zhongwu Guo; D. Venkat Reddy; Peter L. Rinaldi; Vincent M. Monnier
Tags: ascorbic acid, catabolism, lens (device), lens, crystalline, spectrum analysis
Investigative Ophthalmology & Visual Science May 2003, Vol.44, 2047-2058. doi:https://doi.org/10.1167/iovs.02-0575
Influence of Age, Diabetes, and Cataract on Calcium, Lipid-Calcium, and Protein-Calcium Relationships in Human Lenses Free
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Daxin Tang; Douglas Borchman; Marta C. Yappert; Gijs F. J. M. Vrensen; Vittorio Rasi
Tags: calcium, lens, crystalline, lipids, proteins, lens (device)
Investigative Ophthalmology & Visual Science May 2003, Vol.44, 2059-2066. doi:https://doi.org/10.1167/iovs.02-0345
Oxidative Damage to Human Lens Epithelial Cells in Culture: Estrogen Protection of Mitochondrial Potential, ATP, and Cell Viability Free
PDF
Xiaofei Wang; James W. Simpkins; James A. Dykens; Patrick R. Cammarata
Tags: cell survival, epithelial cells, estrogen, lens, crystalline, mitochondria
Investigative Ophthalmology & Visual Science May 2003, Vol.44, 2067-2075. doi:https://doi.org/10.1167/iovs.02-0841
In Vitro Study on the Closure of Posterior Capsulorrhexis in the Human Eye Free
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Veva De Groot; Gijs F. J. M. Vrensen; Ben Willekens; Yasmine Van Tenten; Marie-José Tassignon
Tags: capsulorhexis, eye, tissue membrane
Investigative Ophthalmology & Visual Science May 2003, Vol.44, 2076-2083. doi:https://doi.org/10.1167/iovs.02-0525
Spectrum and Range of Oxidative Stress Responses of Human Lens Epithelial Cells to H2O2 Insult Free
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Sumanta Goswami; Nancy L. Sheets; Jiři Zavadil; Bharesh K. Chauhan; Erwin P. Bottinger; Venkat N. Reddy; Marc Kantorow; Aleš Cvekl
Tags: epithelial cells, genes, lens, crystalline, oxidative stress, proteins
Investigative Ophthalmology & Visual Science May 2003, Vol.44, 2084-2093. doi:https://doi.org/10.1167/iovs.02-0882
Response of Lens Epithelial Cells to Injury: Role of Lumican in Epithelial-Mesenchymal Transition Free
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Shizuya Saika; Takeshi Miyamoto; Sai-ichi Tanaka; Takeshi Tanaka; Iku Ishida; Yoshitaka Ohnishi; Akira Ooshima; Toshiyuki Ishiwata; Goro Asano; Tai-ichiro Chikama; Atsushi Shiraishi; Chia-Yang Liu; Candace W.-C. Kao; Winston W.-Y. Kao
Tags: epithelial to mesenchymal transition, lens (device), lens epithelial cell, lens, crystalline, mice
Investigative Ophthalmology & Visual Science May 2003, Vol.44, 2094-2102. doi:https://doi.org/10.1167/iovs.02-1059
Stimulation of Lens Cell Differentiation by Gap Junction Protein Connexin 45.6 Free
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Sumin Gu; X. Sean Yu; Xinye Yin; Jean X. Jiang
Tags: gap junction protein, lens (device), lens cell, lens, crystalline, retroviridae
Investigative Ophthalmology & Visual Science May 2003, Vol.44, 2103-2111. doi:https://doi.org/10.1167/iovs.02-1045

Physiology and Pharmacology

Comparative Toxicity and Concentrations of Intravitreal Amphotericin B Formulations in a Rabbit Model Free
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Joan P. Cannon; Richard Fiscella; Sutthiporn Pattharachayakul; Kevin W. Garey; Felipe De Alba; Stephen Piscitelli; Deepak P. Edward; Larry H. Danziger
Tags: amphotericin b, oryctolagus cuniculus, toxic effect, eye, amphotericin b, deoxycholate drug combination
Investigative Ophthalmology & Visual Science May 2003, Vol.44, 2112-2117. doi:https://doi.org/10.1167/iovs.02-1020
Aqueous Humor Dynamics and Trabecular Meshwork and Anterior Ciliary Muscle Morphologic Changes with Age in Rhesus Monkeys Free
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B’Ann True Gabelt; Johannes Gottanka; Elke Lütjen-Drecoll; Paul L. Kaufman
Tags: aqueous humor, cercopithecidae, ciliary muscle, macaca mulatta, trabecular meshwork
Investigative Ophthalmology & Visual Science May 2003, Vol.44, 2118-2125. doi:https://doi.org/10.1167/iovs.02-0569
Choroidal Blood Flow during Exercise-Induced Changes in the Ocular Perfusion Pressure Free
PDF
John V. Lovasik; Hélène Kergoat; Charles E. Riva; Benno L. Petrig; Martial Geiser
Tags: bicycling, exercise, perfusion, recovery of function, vascular flow
Investigative Ophthalmology & Visual Science May 2003, Vol.44, 2126-2132. doi:https://doi.org/10.1167/iovs.02-0825

Retina

Monitoring Retinal Function during Transpupillary Thermotherapy for Occult Choroidal Neovascularization in Age-Related Macular Degeneration Free
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Benedetto Falsini; Francesco Focosi; Fernando Molle; Chiara Manganelli; Giancarlo Iarossi; Antonello Fadda; Giorgio Dorin; Martin A. Mainster
Tags: age-related macular degeneration, choroidal neovascularization, heat application, therapeutic, lasers, eye
Investigative Ophthalmology & Visual Science May 2003, Vol.44, 2133-2140. doi:https://doi.org/10.1167/iovs.02-0716
Human Retinal Molecular Weight Exclusion Limit and Estimate of Species Variation Free
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Timothy L. Jackson; Richard J. Antcliff; Jost Hillenkamp; John Marshall
Tags: body tissue, dextran, dextrans, diffusion, fluorescein-5-isothiocyanate
Investigative Ophthalmology & Visual Science May 2003, Vol.44, 2141-2146. doi:https://doi.org/10.1167/iovs.02-1027
Sequence of Early Vascular Events after Photodynamic Therapy Free
PDF
Stephan Michels; Ursula Schmidt-Erfurth
Tags: choroidal neovascularization, photochemotherapy, angiogram, eye, diagnostic imaging
Investigative Ophthalmology & Visual Science May 2003, Vol.44, 2147-2154. doi:https://doi.org/10.1167/iovs.02-0604
VEGF164 Is Proinflammatory in the Diabetic Retina Free
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Susumu Ishida; Tomohiko Usui; Kenji Yamashiro; Yuichi Kaji; Ednan Ahmed; Karen G. Carrasquillo; Shiro Amano; Tetsuo Hida; Yoshihisa Oguchi; Anthony P. Adamis
Tags: diabetes mellitus, leukostasis, retina, vascular endothelial growth factor a, intercellular adhesion molecule 1
Investigative Ophthalmology & Visual Science May 2003, Vol.44, 2155-2162. doi:https://doi.org/10.1167/iovs.02-0807
Production and Activation of Matrix Metalloproteinase-2 in Proliferative Diabetic Retinopathy Free
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Kousuke Noda; Susumu Ishida; Makoto Inoue; Ken-ichi Obata; Yoshihisa Oguchi; Yasunori Okada; Eiji Ikeda
Tags: body tissue, gelatinase a, proliferative diabetic retinopathy, vitreous body, matrix metalloproteinases
Investigative Ophthalmology & Visual Science May 2003, Vol.44, 2163-2170. doi:https://doi.org/10.1167/iovs.02-0662
Mutations in the Pre-mRNA Splicing-Factor Genes PRPF3, PRPF8, and PRPF31 in Spanish Families with Autosomal Dominant Retinitis Pigmentosa Free
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María Martínez-Gimeno; María José Gamundi; Imma Hernan; Miquel Maseras; Elena Millá; Carmen Ayuso; Blanca García-Sandoval; Magdalena Beneyto; Concha Vilela; Montserrat Baiget; Guillermo Antiñolo; Miguel Carballo
Tags: family, genes, heterogeneous nuclear rna, mutation, retinitis pigmentosa
Investigative Ophthalmology & Visual Science May 2003, Vol.44, 2171-2177. doi:https://doi.org/10.1167/iovs.02-0871
An Early-Onset Autosomal Dominant Macular Dystrophy (MCDR3) Resembling North Carolina Macular Dystrophy Maps to Chromosome 5 Free
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Michel Michaelides; Samantha Johnson; Alok K. Tekriwal; Graham E. Holder; Caren Bellmann; Esther Kinning; Geoffrey Woodruff; Richard C. Trembath; David M. Hunt; Anthony T. Moore
Tags: chromosomes, human, pair 5, macular dystrophy, maps, genetic linkage analysis
Investigative Ophthalmology & Visual Science May 2003, Vol.44, 2178-2183. doi:https://doi.org/10.1167/iovs.02-1094
Contribution of TNF-α to Leukocyte Adhesion, Vascular Leakage, and Apoptotic Cell Death in Endotoxin-Induced Uveitis In Vivo Free
PDF
Kan Koizumi; Vassiliki Poulaki; Sven Doehmen; Gerhard Welsandt; Sven Radetzky; Alexandra Lappas; Norbert Kociok; Bernd Kirchhof; Antonia M. Joussen
Tags: cell death, endotoxins, etanercept, leukocyte cell adhesion, leukocytes
Investigative Ophthalmology & Visual Science May 2003, Vol.44, 2184-2191. doi:https://doi.org/10.1167/iovs.02-0589
Insulin-like Growth Factor-I and its Receptor in Neovascular Age-Related Macular Degeneration Free
PDF
Antoinette C. Lambooij; Karel H. M. van Wely; Dicky J. Lindenbergh-Kortleve; Robert W. A. M. Kuijpers; Mike Kliffen; Cornelia M. Mooy
Tags: exudative age-related macular degeneration, insulin-like growth factor i, choroidal neovascularization, rna, messenger, in situ hybridization
Investigative Ophthalmology & Visual Science May 2003, Vol.44, 2192-2198. doi:https://doi.org/10.1167/iovs.02-0410
Retinal Pigment Epithelium Wound Healing in Human Bruch’s Membrane Explants Free
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Hao Wang; Yoshihiko Ninomiya; Ilene K. Sugino; Marco A. Zarbin
Tags: bruch's basal membrane, debridement, retinal pigment epithelium, wound healing, wounds and injuries
Investigative Ophthalmology & Visual Science May 2003, Vol.44, 2199-2210. doi:https://doi.org/10.1167/iovs.02-0435

Retinal Cell Biology

Differential Temporal and Spatial Expression of Immediate Early Genes in Retinal Neurons after Ischemia–Reperfusion Injury Free
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Nagahisa Yoshimura; Takanobu Kikuchi; Sachiko Kuroiwa; Satoko Gaun
Tags: genes, genes, immediate-early, neurons, polymerase chain reaction, reperfusion injury
Investigative Ophthalmology & Visual Science May 2003, Vol.44, 2211-2220. doi:https://doi.org/10.1167/iovs.02-0704
GDNF Regulates Chicken Rod Photoreceptor Development and Survival in Reaggregated Histotypic Retinal Spheres Free
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Andrée Rothermel; Paul G. Layer
Tags: glial cell-line derived neurotrophic factor, rod photoreceptors, chickens
Investigative Ophthalmology & Visual Science May 2003, Vol.44, 2221-2228. doi:https://doi.org/10.1167/iovs.02-0915
Generation of Activated Sialoadhesin-Positive Microglia during Retinal Degeneration Free
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Edward H. Hughes; Frank C. Schlichtenbrede; Conor C. Murphy; Gian-Marco Sarra; Philip J. Luthert; Robin R. Ali; Andrew D. Dick
Tags: microglia, retinal degeneration, photoreceptors
Investigative Ophthalmology & Visual Science May 2003, Vol.44, 2229-2234. doi:https://doi.org/10.1167/iovs.02-0824
Cell Cycle Regulation in Retinal Progenitors by Glia-Derived Neurotrophic Factor and Docosahexaenoic Acid Free
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M. Fernanda Insua; Andrés Garelli; Nora P. Rotstein; O. Lorena German; Andrés Arias; Luis E. Politi
Tags: cdkn1b gene, cell cycle, cell cycle control, docosahexaenoic acids, glial cell-line derived neurotrophic factor
Investigative Ophthalmology & Visual Science May 2003, Vol.44, 2235-2244. doi:https://doi.org/10.1167/iovs.02-0952
DNA Is a Target of the Photodynamic Effects Elicited in A2E-Laden RPE by Blue-Light Illumination Free
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Janet R. Sparrow; Jilin Zhou; Bolin Cai
Tags: blue light, dna, dna damage, light, lighting
Investigative Ophthalmology & Visual Science May 2003, Vol.44, 2245-2251. doi:https://doi.org/10.1167/iovs.02-0746
Protective Effect of Docosahexaenoic Acid on Oxidative Stress-Induced Apoptosis of Retina Photoreceptors Free
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Nora P. Rotstein; Luis E. Politi; O. Lorena German; Romina Girotti
Tags: apoptosis, docosahexaenoic acids, paraquat, photoreceptors, retina
Investigative Ophthalmology & Visual Science May 2003, Vol.44, 2252-2259. doi:https://doi.org/10.1167/iovs.02-0901
Isolation of the Mouse Nyctalopin Gene Nyx and Expression Studies in Mouse and Rat Retina Free
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Katrin Pesch; Christina Zeitz; Julia E. Fries; Stefanie Münscher; Carsten M. Pusch; Konrad Kohler; Wolfgang Berger; Bernd Wissinger
Tags: genes, mice, patient isolation, retina, social isolation
Investigative Ophthalmology & Visual Science May 2003, Vol.44, 2260-2266. doi:https://doi.org/10.1167/iovs.02-0115

Visual Neuroscience

Retinal Spectral Sensitivity, Fur Coloration, and Urine Reflectance in the Genus Octodon (Rodentia): Implications for Visual Ecology Free
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Andrés E. Chávez; Francisco Bozinovic; Leo Peichl; Adrián G. Palacios
Tags: ecology, electroretinography, rodentia, ultraviolet rays, urine
Investigative Ophthalmology & Visual Science May 2003, Vol.44, 2290-2296. doi:https://doi.org/10.1167/iovs.02-0670

Visual Psychophysics and Physiological Optics

Simple Reaction Times in Color Space: The Influence of Chromaticity, Contrast, and Cone Opponency Free
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Declan J. McKeefry; Neil R. A. Parry; Ian J. Murray
Tags: color, reaction time, retinal cone
Investigative Ophthalmology & Visual Science May 2003, Vol.44, 2267-2276. doi:https://doi.org/10.1167/iovs.02-0772
Loss of Cone Function in Age-Related Maculopathy Free
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Joanna A. Phipps; Robyn H. Guymer; Algis J. Vingrys
Tags: age-related macular degeneration, color, contrast sensitivity, retinal cone, steady state
Investigative Ophthalmology & Visual Science May 2003, Vol.44, 2277-2283. doi:https://doi.org/10.1167/iovs.02-0769
Nearwork-Induced Transient Myopia in Preadolescent Hong Kong Chinese Free
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James Stuart Wolffsohn; Bernard Gilmartin; Roger Wing-hong Li; Marion Hastings Edwards; Sandy Wing-shan Chat; John Kwok-fai Lew; Bibianna Sin-ying Yu
Tags: chinese (other dialects), chinese people, hong kong, myopia, myopia transient
Investigative Ophthalmology & Visual Science May 2003, Vol.44, 2284-2289. doi:https://doi.org/10.1167/iovs.02-0373

Erratum

Erratum Free
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Investigative Ophthalmology & Visual Science May 2003, Vol.44, 1813. doi:
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