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Editorial

IOVS Statement on “Double Publication” Free
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Robert N. Frank
Tags: ethics, peer review, science, societies, academia (organization)
Investigative Ophthalmology & Visual Science May 2005, Vol.46, 1549-1550. doi:https://doi.org/10.1167/iovs.05-0278

Anatomy and Pathology/Oncology

Persistent Hyperplastic Primary Vitreous in Transgenic Mice Expressing IE180 of the Pseudorabies Virus Free
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Satoshi Taharaguchi; Kazuhiko Yoshida; Yukiko Tomioka; Saori Yoshino; Toshimitsu Uede; Etsuro Ono
Tags: eye, herpesvirus 1, suid, mice, transgenic, persistent hyperplastic primary vitreous, mice
Investigative Ophthalmology & Visual Science May 2005, Vol.46, 1551-1556. doi:https://doi.org/10.1167/iovs.04-0743
Experimental Percutaneous Cannulation of the Supraorbital Arteries: Implication for Future Therapy Free
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Oliver K. Schwenn; Eike Gunther Wüstenberg; Moritz A. Konerding; Lars-Olof Hattenbach
Tags: catheterization, cadaver, tissue dissection, doppler continuous wave
Investigative Ophthalmology & Visual Science May 2005, Vol.46, 1557-1560. doi:https://doi.org/10.1167/iovs.04-1129
Functional Analysis of the p53 Pathway in Response to Ionizing Radiation in Uveal Melanoma Free
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Young Sun; Binh N. Tran; Lori A. Worley; Rachel B. Delston; J. William Harbour
Tags: radiation, ionizing, uveal melanoma, western blotting
Investigative Ophthalmology & Visual Science May 2005, Vol.46, 1561-1564. doi:https://doi.org/10.1167/iovs.04-1362

Biochemistry and Molecular Biology

TNF−857T, a Genetic Risk Marker for Acute Anterior Uveitis Free
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Ni-Wen Kuo; Penny A. Lympany; Victor Menezo; Anna L. Lagan; Sally John; Tun Kuan Yeo; Sidath Liyanage; Roland M. du Bois; Kenneth I. Welsh; Susan Lightman
Tags: genetic risk, single nucleotide polymorphism, tumor necrosis factors, uveitis, anterior, alleles
Investigative Ophthalmology & Visual Science May 2005, Vol.46, 1565-1571. doi:https://doi.org/10.1167/iovs.04-0932
The Lacrimal Gland Transcriptome Is an Unusually Rich Source of Rare and Poorly Characterized Gene Transcripts Free
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Aylin M. Ozyildirim; Graeme J. Wistow; James Gao; Jiahu Wang; Douglas P. Dickinson; Henry F. Frierson, Jr; Gordon W. Laurie
Tags: genes, lacrimal gland, proteins, mice
Investigative Ophthalmology & Visual Science May 2005, Vol.46, 1572-1580. doi:https://doi.org/10.1167/iovs.04-1380
Whole-Body Bioluminescent Imaging of Human Uveal Melanoma in a New Mouse Model of Local Tumor Growth and Metastasis Free
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Irene C. Notting; Jeroen T. Buijs; Ivo Que; Ratna E. Mintardjo; Geertje van der Horst; Marcel Karperien; Guy S. O. A. Missotten; Nicoline E. Schalij-Delfos; Jan E. E. Keunen; Gabri van der Pluijm
Tags: bioluminescence, diagnostic imaging, mice, neoplasm metastasis, tumor growth
Investigative Ophthalmology & Visual Science May 2005, Vol.46, 1581-1587. doi:https://doi.org/10.1167/iovs.04-0245

Clinical and Epidemiologic Research

Heritability of Refractive Error and Familial Aggregation of Myopia in an Elderly American Population Free
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Robert Wojciechowski; Nathan Congdon; Heidi Bowie; Beatriz Munoz; Donna Gilbert; Sheila K. West
Tags: myopia, refractive errors, older adult, relationship - sibling
Investigative Ophthalmology & Visual Science May 2005, Vol.46, 1588-1592. doi:https://doi.org/10.1167/iovs.04-0740
Association between Symptoms and Signs of Dry Eye among an Elderly Chinese Population in Taiwan: The Shihpai Eye Study Free
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Pei-Yu Lin; Ching-Yu Cheng; Wen-Ming Hsu; Su-Ying Tsai; Ming-Wei Lin; Jorn-Hon Liu; Pesus Chou
Tags: dry eye syndromes, eye, signs and symptoms, taiwan, older adult
Investigative Ophthalmology & Visual Science May 2005, Vol.46, 1593-1598. doi:https://doi.org/10.1167/iovs.04-0864

Cornea

No Pathogenic Mutations Identified in the COL8A2 Gene or Four Positional Candidate Genes in Patients with Posterior Polymorphous Corneal Dystrophy Free
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Vivek S. Yellore; Sylvia A. Rayner; Leslie Emmert-Buck; Geoffrey C. Tabin; Irving Raber; Sadeer B. Hannush; R. Doyle Stulting; Kapil Sampat; Rominder Momi; Alexandre H. Principe; Anthony J. Aldave
Tags: candidate disease gene, genes, mutation, polymorphous corneal dystrophy, polymerase chain reaction
Investigative Ophthalmology & Visual Science May 2005, Vol.46, 1599-1603. doi:https://doi.org/10.1167/iovs.04-1321
Detection and Quantification of Sulfated Disaccharides from Keratan Sulfate and Chondroitin/Dermatan Sulfate during Chick Corneal Development by ESI-MS/MS Free
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Yuntao Zhang; Abigail H. Conrad; Elena S. Tasheva; Ke An; Lolita M. Corpuz; Yutaka Kariya; Kiyoshi Suzuki; Gary W. Conrad
Tags: cornea, disaccharides, chondroitin
Investigative Ophthalmology & Visual Science May 2005, Vol.46, 1604-1614. doi:https://doi.org/10.1167/iovs.04-1453
Dynamic Changes in the Tear Film in Dry Eyes Free
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Robert Montés-Micó; Jorge L. Alió; W. Neil Charman
Tags: dry eye syndromes, tear film finding, eye
Investigative Ophthalmology & Visual Science May 2005, Vol.46, 1615-1619. doi:https://doi.org/10.1167/iovs.05-0017
Sphere Formation and Expression of Neural Proteins by Human Corneal Stromal Cells In Vitro Free
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Saiko Uchida; Seiichi Yokoo; Yasuo Yanagi; Tomohiko Usui; Chinatsu Yokota; Tatsuya Mimura; Makoto Araie; Satoru Yamagami; Shiro Amano
Tags: cornea, immunocytochemistry, proteins, reverse transcriptase polymerase chain reaction, stromal cells
Investigative Ophthalmology & Visual Science May 2005, Vol.46, 1620-1625. doi:https://doi.org/10.1167/iovs.04-0288
Human Corneal Endothelial Cell Precursors Isolated by Sphere-Forming Assay Free
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Seiichi Yokoo; Satoru Yamagami; Yasuo Yanagi; Saiko Uchida; Tatsuya Mimura; Tomohiko Usui; Shiro Amano
Tags: cornea, endothelial cells, immunocytochemistry, reverse transcriptase polymerase chain reaction, glial fibrillary acidic protein
Investigative Ophthalmology & Visual Science May 2005, Vol.46, 1626-1631. doi:https://doi.org/10.1167/iovs.04-1263
Ocular Surface Reconstruction Using Autologous Rabbit Oral Mucosal Epithelial Sheets Fabricated Ex Vivo on a Temperature-Responsive Culture Surface Free
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Yasutaka Hayashida; Kohji Nishida; Masayuki Yamato; Katsuhiko Watanabe; Naoyuki Maeda; Hitoshi Watanabe; Akihiko Kikuchi; Teruo Okano; Yasuo Tano
Tags: body temperature, body tissue, epithelial cells, epithelium, oral mucous membrane
Investigative Ophthalmology & Visual Science May 2005, Vol.46, 1632-1639. doi:https://doi.org/10.1167/iovs.04-0813
Treatment of Ocular Tissues Exposed to Nitrogen Mustard: Beneficial Effect of Zinc Desferrioxamine Combined with Steroids Free
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Yair Morad; Eyal Banin; Edward Averbukh; Eduard Berenshtein; Alexey Obolensky; Mordechai Chevion
Tags: antioxidants, body tissue, deferoxamine, mechlorethamine, normal saline
Investigative Ophthalmology & Visual Science May 2005, Vol.46, 1640-1646. doi:https://doi.org/10.1167/iovs.04-1165
Flt-1 Intraceptors Inhibit Hypoxia-Induced VEGF Expression In Vitro and Corneal Neovascularization In Vivo Free
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Nirbhai Singh; Shivan Amin; Elizabeth Richter; Saadia Rashid; Vincent Scoglietti; Pooja D. Jani; Jin Wang; Rajwinder Kaur; Jayakrishna Ambati; Zheng Dong; Balamurali K. Ambati
Tags: corneal neovascularization, hypoxia, vascular endothelial growth factor a, vegfr-1, cornea
Investigative Ophthalmology & Visual Science May 2005, Vol.46, 1647-1652. doi:https://doi.org/10.1167/iovs.04-1172
Serum-Free Spheroid Culture of Mouse Corneal Keratocytes Free
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Satoru Yoshida; Shigeto Shimmura; Jun Shimazaki; Naoshi Shinozaki; Kazuo Tsubota
Tags: cornea, keratocytes, mice, gel, collagen
Investigative Ophthalmology & Visual Science May 2005, Vol.46, 1653-1658. doi:https://doi.org/10.1167/iovs.04-1405

Glaucoma

A New Statistical Approach for Quantifying Change in Series of Retinal and Optic Nerve Head Topography Images Free
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Andrew J. Patterson; David F. Garway-Heath; Nicholas G. Strouthidis; David P. Crabb
Tags: antidepressive agents, tricyclic, computer simulation, glaucoma, optic disk, pixel
Investigative Ophthalmology & Visual Science May 2005, Vol.46, 1659-1667. doi:https://doi.org/10.1167/iovs.04-0953

Immunology and Microbiology

Synthesis of α-Chemokines IP-10, I-TAC, and MIG Are Differentially Regulated in Human Corneal Keratocytes Free
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Karla A. McInnis; Andrea Britain; Robert N. Lausch; John E. Oakes
Tags: chemokines, cornea, teller acuity cards, trigeminal autonomic cephalalgias, tumor necrosis factors
Investigative Ophthalmology & Visual Science May 2005, Vol.46, 1668-1674. doi:https://doi.org/10.1167/iovs.04-1010
Local Gene Transfer to Modulate Rat Corneal Allograft Rejection Free
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Claire F. Jessup; Helen M. Brereton; Pamela J. Sykes; Michael A. Thiel; Douglas J. Coster; Keryn A. Williams
Tags: adenoviruses, allografting, cornea, rejection (psychology), single-chain antibodies
Investigative Ophthalmology & Visual Science May 2005, Vol.46, 1675-1681. doi:https://doi.org/10.1167/iovs.04-1140

Lens

Human Lens Phospholipid Changes with Age and Cataract Free
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Li Huang; Vahid Grami; Yernan Marrero; Daxin Tang; Marta C. Yappert; Vittorio Rasi; Douglas Borchman
Tags: cataract, lens, crystalline, lipids, phospholipids
Investigative Ophthalmology & Visual Science May 2005, Vol.46, 1682-1689. doi:https://doi.org/10.1167/iovs.04-1155
Noncontact Optical Measurement of Lens Capsule Thickness in Human, Monkey, and Rabbit Postmortem Eyes Free
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Noël M. Ziebarth; Fabrice Manns; Stephen R. Uhlhorn; Anna S. Venkatraman; Jean-Marie Parel
Tags: cercopithecidae, eye, lens capsule, crystalline, optics, oryctolagus cuniculus
Investigative Ophthalmology & Visual Science May 2005, Vol.46, 1690-1697. doi:https://doi.org/10.1167/iovs.05-0039

Physiology and Pharmacology

Ocular Vasodynamic Changes in Light and Darkness in Smokers Free
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Ulf Havelius; Flemming Hansen
Tags: central retinal artery, darkness, smoking, eye, fluid flow
Investigative Ophthalmology & Visual Science May 2005, Vol.46, 1698-1705. doi:https://doi.org/10.1167/iovs.04-0756
Acute Effects of PGF2α on MMP-2 Secretion from Human Ciliary Muscle Cells: A PKC- and ERK-Dependent Process Free
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Shahid Husain; Farahdiba Jafri; Craig E. Crosson
Tags: bodily secretions, ciliary muscle, gelatinase a, latanoprost, gel
Investigative Ophthalmology & Visual Science May 2005, Vol.46, 1706-1713. doi:https://doi.org/10.1167/iovs.04-0993
Systemic Hyperoxia and Retinal Vasomotor Responses Free
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Seendy Jean-Louis; John V. Lovasik; Hélène Kergoat
Tags: hyperoxia, oxygen, retinal vessels, diameter, inspiration
Investigative Ophthalmology & Visual Science May 2005, Vol.46, 1714-1720. doi:https://doi.org/10.1167/iovs.04-1216
Short-Term Increase of Intraocular Pressure Does Not Alter the Response of Retinal and Optic Nerve Head Blood Flow to Flicker Stimulation Free
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Gerhard Garhöfer; Hemma Resch; Günther Weigert; Solveig Lung; Christian Simader; Leopold Schmetterer
Tags: intraocular pressure, optic disk, photopsia, vascular flow, retinal vessels
Investigative Ophthalmology & Visual Science May 2005, Vol.46, 1721-1725. doi:https://doi.org/10.1167/iovs.04-1347

Retina

Association of HLA Class I and Class II Polymorphisms with Age-Related Macular Degeneration Free
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Srini V. Goverdhan; Martin W. Howell; Robert F. Mullins; Clive Osmond; Peter R. Hodgkins; James Self; Kim Avery; Andrew J. Lotery
Tags: human leukocyte antigens, age-related macular degeneration, polymorphism
Investigative Ophthalmology & Visual Science May 2005, Vol.46, 1726-1734. doi:https://doi.org/10.1167/iovs.04-0928
Screen of the IMPDH1 Gene among Patients with Dominant Retinitis Pigmentosa and Clinical Features Associated with the Most Common Mutation, Asp226Asn Free
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Yuko Wada; Michael A. Sandberg; Terri L. McGee; Melissa A. Stillberger; Eliot L. Berson; Thaddeus P. Dryja
Tags: genes, mutation, retinitis pigmentosa, electroretinography
Investigative Ophthalmology & Visual Science May 2005, Vol.46, 1735-1741. doi:https://doi.org/10.1167/iovs.04-1197
Early-Onset, Autosomal Recessive, Progressive Retinal Atrophy in Persian Cats Free
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HyungChul Rah; David J. Maggs; Thomas N. Blankenship; Kristina Narfstrom; Leslie A. Lyons
Tags: adaptive testing, atrophy, autosomal recessive inheritance, breeding, cats
Investigative Ophthalmology & Visual Science May 2005, Vol.46, 1742-1747. doi:https://doi.org/10.1167/iovs.04-1019

Retinal Cell Biology

Time Course of Neurotrophic Factor Upregulation and Retinal Protection against Light-Induced Damage after Optic Nerve Section Free
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Krisztina Valter; Silvia Bisti; Claudia Gargini; Silvia Di Loreto; Rita Maccarone; Luigi Cervetto; Jonathan Stone
Tags: ciliary neurotrophic factor, fibroblast growth factor 2, nerve growth factors, neurons, optic nerve
Investigative Ophthalmology & Visual Science May 2005, Vol.46, 1748-1754. doi:https://doi.org/10.1167/iovs.04-0657
Human RPE Expression of Cell Survival Factors Free
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Ping Yang; Jessica L. Wiser; James J. Peairs; Jessica N. Ebright; Zachary J. Zavodni; Catherine Bowes Rickman; Glenn J. Jaffe
Tags: casp8 and fadd-like apoptosis regulating protein, cell survival, prognostic factors, proteins, retinal pigment cell
Investigative Ophthalmology & Visual Science May 2005, Vol.46, 1755-1764. doi:https://doi.org/10.1167/iovs.04-1039
Nuclear Gene Expression Changes Due to Mitochondrial Dysfunction in ARPE-19 Cells: Implications for Age-Related Macular Degeneration Free
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Michael V. Miceli; S. Michal Jazwinski
Tags: age-related macular degeneration, gene expression, mitochondria, pathophysiology, genes
Investigative Ophthalmology & Visual Science May 2005, Vol.46, 1765-1773. doi:https://doi.org/10.1167/iovs.04-1327

Visual Neuroscience

Useful Visual Field Reduction as a Function of Age and Risk of Accident in Simulated Car Driving Free
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Joceline Rogé; Thierry Pébayle; Aurélie Campagne; Alain Muzet
Tags: accidents, visual fields, automobile driving
Investigative Ophthalmology & Visual Science May 2005, Vol.46, 1774-1779. doi:https://doi.org/10.1167/iovs.04-0540
Cortical Activation Via an Implanted Wireless Retinal Prosthesis Free
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Peter Walter; Zoltán F. Kisvárday; Michael Görtz; Nils Alteheld; Gernot Rossler; Thomas Stieglitz; Ulf T. Eysel
Tags: diagnostic imaging, implants, optics, visual prosthesis, wireless technology
Investigative Ophthalmology & Visual Science May 2005, Vol.46, 1780-1785. doi:https://doi.org/10.1167/iovs.04-0924

Visual Psychophysics and Physiological Optics

A VEP Measure of the Binocular Fusion of Horizontal and Vertical Disparities Free
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Julia Hale; Richard A. Harrad; Suzanne P. McKee; Mark W. Pettet; Anthony M. Norcia
Tags: evoked potentials, visual, health disparity, eye
Investigative Ophthalmology & Visual Science May 2005, Vol.46, 1786-1790. doi:https://doi.org/10.1167/iovs.04-0954
Cognition, Ocular Accommodation, and Cardiovascular Function in Emmetropes and Late-Onset Myopes Free
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Leon Nicholas Davies; James Stuart Wolffsohn; Bernard Gilmartin
Tags: cardiovascular physiology, cognition, visual accommodation
Investigative Ophthalmology & Visual Science May 2005, Vol.46, 1791-1796. doi:https://doi.org/10.1167/iovs.04-0986
Inducing Form-Deprivation Myopia in Fish Free
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Wei Shen; Mathilakath Vijayan; Jacob G. Sivak
Tags: eye, myopia, lens (device), lens, crystalline
Investigative Ophthalmology & Visual Science May 2005, Vol.46, 1797-1803. doi:https://doi.org/10.1167/iovs.04-1318

Erratum

Erratum Free
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Investigative Ophthalmology & Visual Science May 2005, Vol.46, 1556. doi:
Copyright © 2025 Association for Research in Vision and Ophthalmology.
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