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Anatomy and Pathology/Oncology

Demonstration of an Anterior Diffusional Pathway for Solutes in the Normal Human Eye with High Spatial Resolution Contrast-Enhanced Dynamic MR Imaging Free
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Robert J. Bert; Shelton D. Caruthers; Hernan Jara; Jaroslaw Krejza; Elias R. Melhem; Nancy H. Kolodny; Samuel Patz; Thomas F. Freddo
Tags: anterior chamber of eye, eye, magnetic resonance imaging, noise, vitreous body
Investigative Ophthalmology & Visual Science December 2006, Vol.47, 5153-5162. doi:https://doi.org/10.1167/iovs.05-0372
A Novel Imaging Technique for Experimental Choroidal Neovascularization Free
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Mercedes Campos; Juan Amaral; S. Patricia Becerra; Robert N. Fariss
Tags: choroidal neovascularization, lasers, diagnostic imaging, fluorescein-5-isothiocyanate, laser injuries
Investigative Ophthalmology & Visual Science December 2006, Vol.47, 5163-5170. doi:https://doi.org/10.1167/iovs.06-0156
Retinal Nerve Fiber Layer Measurements in Myopia: An Optical Coherence Tomography Study Free
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Christopher Kai-Shun Leung; Shaheeda Mohamed; King Sai Leung; Carol Yim-Lui Cheung; Sylvia Lai-wa Chan; Daphne Ka-yee Cheng; August Ki-cheung Lee; Gloria Yuk-oi Leung; Srinivas Kamalakara Rao; Dennis Shun Chiu Lam
Tags: myopia, optical coherence tomography, retinal nerve fiber layer, eye
Investigative Ophthalmology & Visual Science December 2006, Vol.47, 5171-5176. doi:https://doi.org/10.1167/iovs.06-0545
Correlation of Heterogeneity for Chromosome 3 Copy Number with Cell Type in Choroidal Melanoma of Mixed-Cell Type Free
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Teresa Sandinha; Maura Farquharson; Ian McKay; Fiona Roberts
Tags: chromosomes, human, pair 3, heterogeneity, malignant melanoma of choroid, monosomy, neoplasms
Investigative Ophthalmology & Visual Science December 2006, Vol.47, 5177-5180. doi:https://doi.org/10.1167/iovs.06-0332

Biochemistry and Molecular Biology

Caspase-1 Ablation Protects Photoreceptors in a Model of Autosomal Dominant Retinitis Pigmentosa Free
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Marijana Samardzija; Andreas Wenzel; Markus Thiersch; Rico Frigg; Charlotte Remé; Christian Grimm
Tags: ablation, caspase-1, photoreceptors, retinal degeneration, mice
Investigative Ophthalmology & Visual Science December 2006, Vol.47, 5181-5190. doi:https://doi.org/10.1167/iovs.06-0556
The Roles of Three Palmitoylation Sites of RPE65 in Its Membrane Association and Isomerohydrolase Activity Free
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Yusuke Takahashi; Gennadiy Moiseyev; Ying Chen; Jian-xing Ma
Tags: proteins, tissue membrane, western blotting, dose fractionation, mutagenesis, site-directed
Investigative Ophthalmology & Visual Science December 2006, Vol.47, 5191-5196. doi:https://doi.org/10.1167/iovs.06-0614
Biological Effects of Thyrotropin Receptor Activation on Human Orbital Preadipocytes Free
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Lei Zhang; Glynn Baker; Dominika Janus; Carol A. Paddon; Dagmar Fuhrer; Marian Ludgate
Tags: thyrotropin receptor
Investigative Ophthalmology & Visual Science December 2006, Vol.47, 5197-5203. doi:https://doi.org/10.1167/iovs.06-0596
Prolonged Rhodopsin Phosphorylation in Light-Induced Retinal Degeneration in Rat Models Free
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Futoshi Ishikawa; Hiroshi Ohguro; Ikuyo Ohguro; Hitoshi Yamazaki; Kazuhisa Mamiya; Tomomi Metoki; Tadashi Ito; Yumiko Yokoi; Mitsuru Nakazawa
Tags: phosphorylation, rats, retinal degeneration, rhodopsin, stress
Investigative Ophthalmology & Visual Science December 2006, Vol.47, 5204-5211. doi:https://doi.org/10.1167/iovs.05-1149
Mutation Causing Self-Aggregation in Human γC-Crystallin Leading to Congenital Cataract Free
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Venu Talla; Chitra Narayanan; Narayanaswamy Srinivasan; Dorairajan Balasubramanian
Tags: crystallins, mutation, congenital cataract, proteins
Investigative Ophthalmology & Visual Science December 2006, Vol.47, 5212-5217. doi:https://doi.org/10.1167/iovs.06-0427
Pax6 Regulation in Retinal Cells by CCCTC Binding Factor Free
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Tie Li; Zhenyu Lu; Luo Lu
Tags: chickens, embryo, galactosidase, mice, transgenic, regulation
Investigative Ophthalmology & Visual Science December 2006, Vol.47, 5218-5226. doi:https://doi.org/10.1167/iovs.06-0254

Clinical and Epidemiologic Research

Dose-Ranging Study of Lutein Supplementation in Persons Aged 60 Years or Older Free
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Julie M. Rosenthal; Jonghyeon Kim; Francisco de Monastario; Darby J. S. Thompson; Richard A. Bone; John T. Landrum; Fabiana F. de Moura; Frederick Khachik; Huiping Chen; Rosemary L. Schleicher; Frederick L. Ferris, III; Emily Y. Chew
Tags: lutein
Investigative Ophthalmology & Visual Science December 2006, Vol.47, 5227-5233. doi:https://doi.org/10.1167/iovs.05-1513
The Effect of Lutein and Zeaxanthin Supplementation on Metabolites of These Carotenoids in the Serum of Persons Aged 60 or Older Free
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Frederick Khachik; Fabiana F. de Moura; Emily Y. Chew; Larry W. Douglass; Frederick L. Ferris, III; Jonghyeon Kim; Darby J. S. Thompson
Tags: carotenoids, lutein, metabolites
Investigative Ophthalmology & Visual Science December 2006, Vol.47, 5234-5242. doi:https://doi.org/10.1167/iovs.06-0504

Cornea

Expression of VSX1 in Human Corneal Keratocytes during Differentiation into Myofibroblasts in Response to Wound Healing Free
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Vanessa Barbaro; Enzo Di Iorio; Stefano Ferrari; Luigi Bisceglia; Alessandro Ruzza; Michele De Luca; Graziella Pellegrini
Tags: cornea, keratocytes, myofibroblasts, wound healing
Investigative Ophthalmology & Visual Science December 2006, Vol.47, 5243-5250. doi:https://doi.org/10.1167/iovs.06-0185
Multiphoton Fluorescence and Second Harmonic Generation Imaging of the Structural Alterations in Keratoconus Ex Vivo Free
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Hsin-Yuan Tan; Yen Sun; Wen Lo; Sung-Jan Lin; Ching-Hsi Hsiao; Yeong-Fong Chen; Samuel Chao-Ming Huang; Wei-Chou Lin; Shiou-Hwa Jee; Hsin-Su Yu; Chen-Yuan Dong
Tags: diagnostic imaging, fluorescence, keratoconus, harmonics, cornea
Investigative Ophthalmology & Visual Science December 2006, Vol.47, 5251-5259. doi:https://doi.org/10.1167/iovs.06-0386
Stimulation of Collagen Synthesis by Insulin and Proteoglycan Accumulation by Ascorbate in Bovine Keratocytes In Vitro Free
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Kurt Musselmann; Bradley Kane; Bridgette Alexandrou; John R. Hassell
Tags: cattle, collagen, collagen synthesis, insulin, keratocytes
Investigative Ophthalmology & Visual Science December 2006, Vol.47, 5260-5266. doi:https://doi.org/10.1167/iovs.06-0612
Phosphatase-Mediated Crosstalk Control of ERK and p38 MAPK Signaling in Corneal Epithelial Cells Free
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Zheng Wang; Hua Yang; Souvenir D. Tachado; José E. Capó-Aponte; Victor N. Bildin; Henry Koziel; Peter S. Reinach
Tags: corneal epithelial cells, mitogen-activated protein kinase p38, phosphoric monoester hydrolases, phosphorylation, signal transduction
Investigative Ophthalmology & Visual Science December 2006, Vol.47, 5267-5275. doi:https://doi.org/10.1167/iovs.06-0642
Cell Surface Glycoconjugate Abnormalities and Corneal Epithelial Wound Healing in the Pax6 +/ − Mouse Model of Aniridia-Related Keratopathy Free
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Romana Kucerova; Jingxing Ou; Diane Lawson; Lucy J. Leiper; J. Martin Collinson
Tags: aniridia, cornea, corneal epithelial cells, epithelium, glycoconjugates
Investigative Ophthalmology & Visual Science December 2006, Vol.47, 5276-5282. doi:https://doi.org/10.1167/iovs.06-0581
Mapping of a Gene Causing Brittle Cornea Syndrome in Tunisian Jews to 16q24 Free
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Almogit Abu; Moshe Frydman; Dina Marek; Eran Pras; Chaim Stolovitch; Ayala Aviram-Goldring; Shlomit Rienstein; Haike Reznik-Wolf; Elon Pras
Tags: dna, ehlers-danlos syndrome 6b, genes, genes, vif, jews
Investigative Ophthalmology & Visual Science December 2006, Vol.47, 5283-5287. doi:https://doi.org/10.1167/iovs.06-0206

Eye Movements, Strabismus, Amblyopia and Neuro-ophthalmology

Reflexive Optokinetic Nystagmus in Younger and Older Observers under Photopic and Mesopic Viewing Conditions Free
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Trevor J. Hine; Guy Wallis; Joanne M. Wood; Efty P. Stavrou
Tags: continuing professional development, eye movement, nystagmus, optokinetic, spatial frequency, velocity
Investigative Ophthalmology & Visual Science December 2006, Vol.47, 5288-5294. doi:https://doi.org/10.1167/iovs.06-0539
Eye Movements of Patients with Tunnel Vision While Walking Free
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Fernando Vargas-Martín; Eli Peli
Tags: bilateral visual field constriction, eye, eye movement, gait, walking (activity)
Investigative Ophthalmology & Visual Science December 2006, Vol.47, 5295-5302. doi:https://doi.org/10.1167/iovs.05-1043
Leber’s Hereditary Optic Neuropathy with Childhood Onset Free
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Piero Barboni; Giacomo Savini; Maria Lucia Valentino; Chiara La Morgia; Costantino Bellusci; Anna Maria De Negri; Federico Sadun; Arturo Carta; Michele Carbonelli; Alfredo A. Sadun; Valerio Carelli
Tags: child, optic atrophy, hereditary, leber, eye
Investigative Ophthalmology & Visual Science December 2006, Vol.47, 5303-5309. doi:https://doi.org/10.1167/iovs.06-0520

Glaucoma

Control of Filtering Bleb Structure through Tissue Bioengineering: An Animal Model Free
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Henry Shen-Lih Chen; Robert Ritch; Theodore Krupin; Wei-Cherng Hsu
Tags: animal model, blister, body tissue, collagen, implants
Investigative Ophthalmology & Visual Science December 2006, Vol.47, 5310-5314. doi:https://doi.org/10.1167/iovs.06-0378
A Genome-wide Scan Maps a Novel Juvenile-Onset Primary Open-Angle Glaucoma Locus to 15q Free
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Dan Yi Wang; Bao Jian Fan; John K. H. Chua; Pancy O. S. Tam; Christopher K. S. Leung; Dennis S. C. Lam; Chi Pui Pang
Tags: child, genome, maps, open-angle glaucoma, haplotypes
Investigative Ophthalmology & Visual Science December 2006, Vol.47, 5315-5321. doi:https://doi.org/10.1167/iovs.06-0179
Measurement Variability in Heidelberg Retina Tomograph Imaging of Neuroretinal Rim Area Free
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Victoria M. F. Owen; Nicholas G. Strouthidis; David F. Garway-Heath; David P. Crabb
Tags: diagnostic imaging, heidelberg retina tomograph, neuroretinal rim, noise, follow-up
Investigative Ophthalmology & Visual Science December 2006, Vol.47, 5322-5330. doi:https://doi.org/10.1167/iovs.06-0096
A Comparison between Multifocal and Conventional VEP Latency Changes Secondary to Glaucomatous Damage Free
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Tomas M. Grippo; Donald C. Hood; Fabio N. Kanadani; Isaac Ezon; Vivienne C. Greenstein; Jeffrey M. Liebmann; Robert Ritch
Tags: evoked potentials, visual, glaucoma, eye
Investigative Ophthalmology & Visual Science December 2006, Vol.47, 5331-5336. doi:https://doi.org/10.1167/iovs.06-0527
Corneal Thickness- and Age-Related Biomechanical Properties of the Cornea Measured with the Ocular Response Analyzer Free
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Aachal Kotecha; Ahmed Elsheikh; Cynthia R. Roberts; Haogang Zhu; David F. Garway-Heath
Tags: cornea, intraocular pressure, eye
Investigative Ophthalmology & Visual Science December 2006, Vol.47, 5337-5347. doi:https://doi.org/10.1167/iovs.06-0557
Automated Analysis of Heidelberg Retina Tomograph Optic Disc Images by Glaucoma Probability Score Free
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Annemiek Coops; David Barry Henson; Anna J. Kwartz; Paul Habib Artes
Tags: glaucoma, magnetic resonance angiography, mineralocorticoid receptor antagonists, optic disk, heidelberg retina tomograph
Investigative Ophthalmology & Visual Science December 2006, Vol.47, 5348-5355. doi:https://doi.org/10.1167/iovs.06-0579
Structure and Function in Glaucoma: The Relationship between a Functional Visual Field Map and an Anatomic Retinal Map Free
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Nicholas G. Strouthidis; Veronica Vinciotti; Allan J. Tucker; Stuart K. Gardiner; David P. Crabb; David F. Garway-Heath
Tags: glaucoma, visual fields, optic disk, filters
Investigative Ophthalmology & Visual Science December 2006, Vol.47, 5356-5362. doi:https://doi.org/10.1167/iovs.05-1660
Microtubule Contribution to the Reflectance of the Retinal Nerve Fiber Layer Free
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Xiang-Run Huang; Robert W. Knighton; Lora N. Cavuoto
Tags: colchicine, microtubules, retinal nerve fiber layer
Investigative Ophthalmology & Visual Science December 2006, Vol.47, 5363-5367. doi:https://doi.org/10.1167/iovs.06-0451
SNPs and Interaction Analyses of Noelin 2, Myocilin, and Optineurin Genes in Japanese Patients with Open-Angle Glaucoma Free
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Tomoyo Funayama; Yukihiko Mashima; Yuichiro Ohtake; Karin Ishikawa; Nobuo Fuse; Noriko Yasuda; Takeo Fukuchi; Akira Murakami; Yoshihiro Hotta; Naoki Shimada; for The Glaucoma Gene Research Group
Tags: genes, glaucoma, intraocular pressure, japanese, myoc gene
Investigative Ophthalmology & Visual Science December 2006, Vol.47, 5368-5375. doi:https://doi.org/10.1167/iovs.06-0196

Immunology and Microbiology

B7+ Iris Pigment Epithelial Cells Convert T Cells into CTLA-4+, B7-Expressing CD8+ Regulatory T Cells Free
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Sunao Sugita; Hiroshi Keino; Yuri Futagami; Hiroshi Takase; Manabu Mochizuki; Joan Stein-Streilein; J. Wayne Streilein
Tags: cytotoxic t-lymphocyte antigen 4, interprofessional education, t-lymphocytes, immune reconstitution inflammatory syndrome, cd80 antigens
Investigative Ophthalmology & Visual Science December 2006, Vol.47, 5376-5384. doi:https://doi.org/10.1167/iovs.05-1354
RPE Cells Resist Bystander Killing by CTLs, but Are Highly Susceptible to Antigen-Dependent CTL Killing Free
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Dale S. Gregerson; Kathleen L. Lew; Scott W. McPherson; Neal D. Heuss; Deborah A. Ferrington
Tags: antigens, killing, peptides, retinal pigment cell, caspase-3
Investigative Ophthalmology & Visual Science December 2006, Vol.47, 5385-5394. doi:https://doi.org/10.1167/iovs.06-0636

Lens

Inhibition of Aldose Reductase Prevents Lipopolysaccharide-Induced Inflammatory Response in Human Lens Epithelial Cells Free
PDF
Agnieszka Pladzyk; Aramati B. M. Reddy; Umesh C. S. Yadav; Ravinder Tammali; Kota V. Ramana; Satish K. Srivastava
Tags: ablation, aldehyde reductase, apoptosis, caspase-3, epithelial cells
Investigative Ophthalmology & Visual Science December 2006, Vol.47, 5395-5403. doi:https://doi.org/10.1167/iovs.06-0469
Biological Response in Various Compartments of the Rat Lens after In Vivo Exposure to UVR-B Analyzed by HR-MAS 1H NMR Spectroscopy Free
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May-Britt Tessem; Tone F. Bathen; Stefan Löfgren; Oddbjørn Sæther; Vino Mody; Linda Meyer; Xiuqin Dong; Per G. Söderberg; Anna Midelfart
Tags: lens (device), lens, crystalline, spectrum analysis, in vivo exposure
Investigative Ophthalmology & Visual Science December 2006, Vol.47, 5404-5411. doi:https://doi.org/10.1167/iovs.05-1633
Contrast Acuity in Cataracts of Different Morphology and Association to Self-Reported Visual Function Free
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Eva Stifter; Stefan Sacu; Arnulf Thaler; Herbert Weghaupt
Tags: cataract, vision, self-report
Investigative Ophthalmology & Visual Science December 2006, Vol.47, 5412-5422. doi:https://doi.org/10.1167/iovs.05-1564

Physiology and Pharmacology

RGC Sensitivity to Mild Systemic Hypoxia Free
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Hélène Kergoat; Marie-Ève Hérard; Marianne Lemay
Tags: hypoxia
Investigative Ophthalmology & Visual Science December 2006, Vol.47, 5423-5427. doi:https://doi.org/10.1167/iovs.06-0602
Chloride Secretion by Porcine Ciliary Epithelium: New Insight into Species Similarities and Differences in Aqueous Humor Formation Free
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Chi-Wing Kong; King-Kit Li; Chi-Ho To
Tags: aqueous humor, bathing, biological transport, bodily secretions, chlorides
Investigative Ophthalmology & Visual Science December 2006, Vol.47, 5428-5436. doi:https://doi.org/10.1167/iovs.06-0180

Retina

Evaluation of the New Photosensitizer Tookad (WST09) for Photodynamic Vessel Occlusion of the Choroidal Tissue in Rabbits Free
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Carsten Framme; Helmut G. Sachs; Barbara Flucke; Dirk Theisen-Kunde; Reginald Birngruber
Tags: angiogram, body tissue, dyes, oryctolagus cuniculus, photosensitizing agents
Investigative Ophthalmology & Visual Science December 2006, Vol.47, 5437-5446. doi:https://doi.org/10.1167/iovs.06-0532
Development of the Electroretinographic Oscillatory Potentials in Normal and ROP Rats Free
PDF
Kegao Liu; James D. Akula; Ronald M. Hansen; Anne Moskowitz; Michael S. Kleinman; Anne B. Fulton
Tags: rats, electroretinography
Investigative Ophthalmology & Visual Science December 2006, Vol.47, 5447-5452. doi:https://doi.org/10.1167/iovs.06-0702
Expanded Genome Scan in Extended Families with Age-Related Macular Degeneration Free
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Sandra Barral; Peter J. Francis; Dennis W. Schultz; Mitchell B. Schain; Chad Haynes; Jacek Majewski; Jurg Ott; Ted Acott; Richard G. Weleber; Michael L. Klein
Tags: age-related macular degeneration, family, genome, choroidal neovascularization, lod score
Investigative Ophthalmology & Visual Science December 2006, Vol.47, 5453-5459. doi:https://doi.org/10.1167/iovs.06-0655
Dynamic and Quantitative Analysis of Choroidal Neovascularization by Fluorescein Angiography Free
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Syed Mahmood Shah; Sinan Tatlipinar; Edward Quinlan; Jennifer U. Sung; Homayoun Tabandeh; Quan Dong Nguyen; Ahmed S. Fahmy; Ingrid Zimmer-Galler; R. C. Andrew Symons; Jesse M. Cedarbaum; Peter A. Campochiaro
Tags: angiogram, choroidal neovascularization, fluorescein, fluorescein angiography, fluorescence
Investigative Ophthalmology & Visual Science December 2006, Vol.47, 5460-5468. doi:https://doi.org/10.1167/iovs.06-0012
Calpain-Specific Proteolysis in Primate Retina: Contribution of Calpains in Cell Death Free
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Emi Nakajima; Larry L. David; Cory Bystrom; Thomas R. Shearer; Mitsuyoshi Azuma
Tags: calpain, proteins, retina, cercopithecidae, proteolysis
Investigative Ophthalmology & Visual Science December 2006, Vol.47, 5469-5475. doi:https://doi.org/10.1167/iovs.06-0567
Chronic Ingestion of (3R,3′R,6′R)-Lutein and (3R,3′R)-Zeaxanthin in the Female Rhesus Macaque Free
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Frederick Khachik; Edra London; Fabiana F. de Moura; Mary Johnson; Scott Steidl; Louis DeTolla; Steven Shipley; Rigoberto Sanchez; Xue-Qing Chen; Jodi Flaws; Gerard Lutty; Scott McLeod; Bruce Fowler
Tags: carotenoids, cercopithecidae, lutein, metabolites, plasma
Investigative Ophthalmology & Visual Science December 2006, Vol.47, 5476-5486. doi:https://doi.org/10.1167/iovs.06-0194
Human Macula Investigated In Vivo with Polarization-Sensitive Optical Coherence Tomography Free
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Michael Pircher; Erich Götzinger; Oliver Findl; Stephan Michels; Wolfgang Geitzenauer; Christina Leydolt; Ursula Schmidt-Erfurth; Christoph K. Hitzenberger
Tags: macula densa, macula lutea, optical coherence tomography, retina, diagnostic imaging
Investigative Ophthalmology & Visual Science December 2006, Vol.47, 5487-5494. doi:https://doi.org/10.1167/iovs.05-1589
Autofluorescence Characteristics of Early, Atrophic, and High-Risk Fellow Eyes in Age-Related Macular Degeneration Free
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R. Theodore Smith; Jackie K. Chan; Mihai Busuoic; Vasuki Sivagnanavel; Alan C. Bird; N. Victor Chong
Tags: age-related macular degeneration, atrophic condition of skin, autofluorescence, drusen, eye
Investigative Ophthalmology & Visual Science December 2006, Vol.47, 5495-5504. doi:https://doi.org/10.1167/iovs.05-1318
CTRP5 Is a Membrane-Associated and Secretory Protein in the RPE and Ciliary Body and the S163R Mutation of CTRP5 Impairs Its Secretion Free
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Md Nawajes A. Mandal; Vidyullatha Vasireddy; G. Bhanuprakash Reddy; XiaoFei Wang; Sayoko E. Moroi; Bikash R. Pattnaik; Bret A. Hughes; John R. Heckenlively; Peter F. Hitchcock; Monica M. Jablonski; Radha Ayyagari
Tags: mutation, proteins, tissue membrane, ciliary body, bodily secretions
Investigative Ophthalmology & Visual Science December 2006, Vol.47, 5505-5513. doi:https://doi.org/10.1167/iovs.06-0312
Spatial and Temporal Expression of MFRP and Its Interaction with CTRP5 Free
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Md Nawajes A. Mandal; Vidyullatha Vasireddy; Monica M. Jablonski; XiaoFei Wang; John R. Heckenlively; Bret A. Hughes; G. Bhanuprakash Reddy; Radha Ayyagari
Tags: antibodies, body tissue, eye, genes, mice
Investigative Ophthalmology & Visual Science December 2006, Vol.47, 5514-5521. doi:https://doi.org/10.1167/iovs.06-0449
Noninvasive Volumetric Imaging and Morphometry of the Rodent Retina with High-Speed, Ultrahigh-Resolution Optical Coherence Tomography Free
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Vivek J. Srinivasan; Tony H. Ko; Maciej Wojtkowski; Mariana Carvalho; Allen Clermont; Sven-Erik Bursell; Qin Hui Song; Janis Lem; Jay S. Duker; Joel S. Schuman; James G. Fujimoto
Tags: diagnostic imaging, optical coherence tomography, retina, rodentia
Investigative Ophthalmology & Visual Science December 2006, Vol.47, 5522-5528. doi:https://doi.org/10.1167/iovs.06-0195
Time-Lapse Imaging of Vitreoretinal Angiogenesis Originating from Both Quiescent and Mature Vessels in a Novel Ex Vivo System Free
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Tomoaki Murakami; Kiyoshi Suzuma; Hitoshi Takagi; Mihori Kita; Hirokazu Ohashi; Daisuke Watanabe; Tomonari Ojima; Masafumi Kurimoto; Tetsushi Kimura; Atsushi Sakamoto; Noriharu Unoki; Nagahisa Yoshimura
Tags: angiogenesis, diagnostic imaging, endothelial cells, neovascularization, pathologic, vascular endothelial growth factor a
Investigative Ophthalmology & Visual Science December 2006, Vol.47, 5529-5536. doi:https://doi.org/10.1167/iovs.06-0373

Retinal Cell Biology

Retinal Pigment Epithelial Cells Synthesize Laminins, Including Laminin 5, and Adhere to Them through α3- and α6-Containing Integrins Free
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Sabine Aisenbrey; Minlei Zhang; Daniel Bacher; Jason Yee; William J. Brunken; Dale D. Hunter
Tags: integrins, laminin, retinal pigment cell, antibodies, biological response modifiers
Investigative Ophthalmology & Visual Science December 2006, Vol.47, 5537-5544. doi:https://doi.org/10.1167/iovs.05-1590
Neuroprotective Effects of Angiotensin II Type 1 Receptor (AT1R) Blocker, Telmisartan, via Modulating AT1R and AT2R Signaling in Retinal Inflammation Free
PDF
Toshihide Kurihara; Yoko Ozawa; Kei Shinoda; Norihiro Nagai; Makoto Inoue; Yuichi Oike; Kazuo Tsubota; Susumu Ishida; Hideyuki Okano
Tags: inflammation, signal transduction, telmisartan, receptor, angiotensin, type 1, synaptophysin
Investigative Ophthalmology & Visual Science December 2006, Vol.47, 5545-5552. doi:https://doi.org/10.1167/iovs.06-0478
Rod Photoreceptor Loss in Rho−/− Mice Reduces Retinal Hypoxia and Hypoxia-Regulated Gene Expression Free
PDF
Tanyth E. de Gooyer; Kathryn A. Stevenson; Pete Humphries; David A. C. Simpson; Timothy M. Curtis; Tom A. Gardiner; Alan W. Stitt
Tags: gene expression, hypoxia, mice, rod photoreceptors, retina
Investigative Ophthalmology & Visual Science December 2006, Vol.47, 5553-5560. doi:https://doi.org/10.1167/iovs.06-0646
Retinopathy Is Reduced during Experimental Diabetes in a Mouse Model of Outer Retinal Degeneration Free
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Tanyth E. de Gooyer; Kathryn A. Stevenson; Pete Humphries; David A. C. Simpson; Tom A. Gardiner; Alan W. Stitt
Tags: diabetes mellitus, diabetes mellitus, type 2, mice, retinal degeneration, retinal diseases
Investigative Ophthalmology & Visual Science December 2006, Vol.47, 5561-5568. doi:https://doi.org/10.1167/iovs.06-0647
Activation of Caspase-8 and Caspase-12 Pathways by 7-Ketocholesterol in Human Retinal Pigment Epithelial Cells Free
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Saurabh Luthra; Babak Fardin; Joyce Dong; Dieter Hertzog; Sami Kamjoo; Simon Gebremariam; Virit Butani; Raja Narayanan; Jeanie K. Mungcal; Baruch D. Kuppermann; M. Cristina Kenney
Tags: caspase-8, caspases, retinal pigment cell, apoptosis
Investigative Ophthalmology & Visual Science December 2006, Vol.47, 5569-5575. doi:https://doi.org/10.1167/iovs.06-0333
Expression, Subcellular Localization, and Regulation of Sigma Receptor in Retinal Müller Cells Free
PDF
Guoliang Jiang; Barbara Mysona; Ying Dun; Jaya P. Gnana-Prakasam; Navjotsin Pabla; Weiguo Li; Zheng Dong; Vadivel Ganapathy; Sylvia B. Smith
Tags: cardiac support procedures, ligands, mast-cell sarcoma, mice, millennium cohort study
Investigative Ophthalmology & Visual Science December 2006, Vol.47, 5576-5582. doi:https://doi.org/10.1167/iovs.06-0608
Loss of BCL-XL in Rod Photoreceptors: Increased Susceptibility to Bright Light Stress Free
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Lixin Zheng; Robert E. Anderson; Martin-Paul Agbaga; Edmund B. Rucker, III; Yun-Zheng Le
Tags: disease susceptibility, mice, photoreceptors, rod photoreceptors, stress
Investigative Ophthalmology & Visual Science December 2006, Vol.47, 5583-5589. doi:https://doi.org/10.1167/iovs.06-0163
Cell Cycle–Specific and Cell Type–Specific Expression of Rb in the Developing Human Retina Free
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Thomas C. Lee; Dena Almeida; Nidia Claros; David H. Abramson; David Cobrinik
Tags: cell cycle, retina, cell nucleus, retinal cone
Investigative Ophthalmology & Visual Science December 2006, Vol.47, 5590-5598. doi:https://doi.org/10.1167/iovs.06-0063

Visual Psychophysics and Physiological Optics

Orientation Discrimination and Contrast Detection Thresholds in Migraine for Cardinal and Oblique Angles Free
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Marc S. Tibber; Antonio Guedes; Alex J. Shepherd
Tags: migraine disorders
Investigative Ophthalmology & Visual Science December 2006, Vol.47, 5599-5604. doi:https://doi.org/10.1167/iovs.06-0640
Contrasting Blue-on-Yellow with White-on-White Visual Fields: Roles of Visual Adaptation for Healthy Peri- or Postmenopausal Women Younger Than 70 Years of Age Free
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Alvin Eisner; Maureen D. Toomey; Lisa J. Incognito; Jean P. O’Malley; John R. Samples
Tags: visual fields, pupil size, shedler-westen assessment procedure–200, postmenopause
Investigative Ophthalmology & Visual Science December 2006, Vol.47, 5605-5614. doi:https://doi.org/10.1167/iovs.05-1612

Lecture

Introducing Trevor D. Lamb and Edward N. Pugh, Jr, the 2006 Recipients of the Proctor Medal Free
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King-Wai Yau
Tags: atrial myxoma with lentigines
Investigative Ophthalmology & Visual Science December 2006, Vol.47, 5137. doi:https://doi.org/10.1167/iovs.06-0187
Phototransduction, Dark Adaptation, and Rhodopsin Regeneration The Proctor Lecture Free
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Trevor D. Lamb; Edward N. Pugh, Jr
Tags: dark adaptation, kinetics, phototransduction, retinoids, rhodopsin
Investigative Ophthalmology & Visual Science December 2006, Vol.47, 5138-5152. doi:https://doi.org/10.1167/iovs.06-0849

Erratum

ERRATUM Free
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Investigative Ophthalmology & Visual Science December 2006, Vol.47, 5162. doi:
ERRATUM Free
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Investigative Ophthalmology & Visual Science December 2006, Vol.47, 5170. doi:
ERRATUM Free
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Investigative Ophthalmology & Visual Science December 2006, Vol.47, 5180. doi:
Copyright © 2025 Association for Research in Vision and Ophthalmology.
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