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Anatomy and Pathology/Oncology

Demonstration of an Anterior Diffusional Pathway for Solutes in the Normal Human Eye with High Spatial Resolution Contrast-Enhanced Dynamic MR Imaging Free
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Robert J. Bert; Shelton D. Caruthers; Hernan Jara; Jaroslaw Krejza; Elias R. Melhem; Nancy H. Kolodny; Samuel Patz; Thomas F. Freddo
Tags: anterior chamber of eye, eye, magnetic resonance imaging, noise, vitreous body
Investigative Ophthalmology & Visual Science December 2006, Vol.47, 5153-5162. doi:10.1167/iovs.05-0372
A Novel Imaging Technique for Experimental Choroidal Neovascularization Free
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Mercedes Campos; Juan Amaral; S. Patricia Becerra; Robert N. Fariss
Tags: choroidal neovascularization, lasers, diagnostic imaging, fluorescein-5-isothiocyanate, laser injuries
Investigative Ophthalmology & Visual Science December 2006, Vol.47, 5163-5170. doi:10.1167/iovs.06-0156
Retinal Nerve Fiber Layer Measurements in Myopia: An Optical Coherence Tomography Study Free
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Christopher Kai-Shun Leung; Shaheeda Mohamed; King Sai Leung; Carol Yim-Lui Cheung; Sylvia Lai-wa Chan; Daphne Ka-yee Cheng; August Ki-cheung Lee; Gloria Yuk-oi Leung; Srinivas Kamalakara Rao; Dennis Shun Chiu Lam
Tags: myopia, optical coherence tomography, retinal nerve fiber layer, eye
Investigative Ophthalmology & Visual Science December 2006, Vol.47, 5171-5176. doi:10.1167/iovs.06-0545
Correlation of Heterogeneity for Chromosome 3 Copy Number with Cell Type in Choroidal Melanoma of Mixed-Cell Type Free
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Teresa Sandinha; Maura Farquharson; Ian McKay; Fiona Roberts
Tags: chromosomes, human, pair 3, heterogeneity, malignant melanoma of choroid, monosomy, neoplasms
Investigative Ophthalmology & Visual Science December 2006, Vol.47, 5177-5180. doi:10.1167/iovs.06-0332

Biochemistry and Molecular Biology

Caspase-1 Ablation Protects Photoreceptors in a Model of Autosomal Dominant Retinitis Pigmentosa Free
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Marijana Samardzija; Andreas Wenzel; Markus Thiersch; Rico Frigg; Charlotte Remé; Christian Grimm
Tags: ablation, caspase-1, photoreceptors, retinal degeneration, mice
Investigative Ophthalmology & Visual Science December 2006, Vol.47, 5181-5190. doi:10.1167/iovs.06-0556
The Roles of Three Palmitoylation Sites of RPE65 in Its Membrane Association and Isomerohydrolase Activity Free
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Yusuke Takahashi; Gennadiy Moiseyev; Ying Chen; Jian-xing Ma
Tags: proteins, tissue membrane, western blotting, dose fractionation, mutagenesis, site-directed
Investigative Ophthalmology & Visual Science December 2006, Vol.47, 5191-5196. doi:10.1167/iovs.06-0614
Biological Effects of Thyrotropin Receptor Activation on Human Orbital Preadipocytes Free
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Lei Zhang; Glynn Baker; Dominika Janus; Carol A. Paddon; Dagmar Fuhrer; Marian Ludgate
Tags: thyrotropin receptor
Investigative Ophthalmology & Visual Science December 2006, Vol.47, 5197-5203. doi:10.1167/iovs.06-0596
Prolonged Rhodopsin Phosphorylation in Light-Induced Retinal Degeneration in Rat Models Free
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Futoshi Ishikawa; Hiroshi Ohguro; Ikuyo Ohguro; Hitoshi Yamazaki; Kazuhisa Mamiya; Tomomi Metoki; Tadashi Ito; Yumiko Yokoi; Mitsuru Nakazawa
Tags: phosphorylation, rats, retinal degeneration, rhodopsin, stress
Investigative Ophthalmology & Visual Science December 2006, Vol.47, 5204-5211. doi:10.1167/iovs.05-1149
Mutation Causing Self-Aggregation in Human γC-Crystallin Leading to Congenital Cataract Free
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Venu Talla; Chitra Narayanan; Narayanaswamy Srinivasan; Dorairajan Balasubramanian
Tags: crystallins, mutation, congenital cataract, proteins
Investigative Ophthalmology & Visual Science December 2006, Vol.47, 5212-5217. doi:10.1167/iovs.06-0427
Pax6 Regulation in Retinal Cells by CCCTC Binding Factor Free
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Tie Li; Zhenyu Lu; Luo Lu
Tags: chickens, embryo, galactosidase, mice, transgenic, regulation
Investigative Ophthalmology & Visual Science December 2006, Vol.47, 5218-5226. doi:10.1167/iovs.06-0254

Clinical and Epidemiologic Research

Dose-Ranging Study of Lutein Supplementation in Persons Aged 60 Years or Older Free
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Julie M. Rosenthal; Jonghyeon Kim; Francisco de Monastario; Darby J. S. Thompson; Richard A. Bone; John T. Landrum; Fabiana F. de Moura; Frederick Khachik; Huiping Chen; Rosemary L. Schleicher; Frederick L. Ferris, III; Emily Y. Chew
Tags: lutein
Investigative Ophthalmology & Visual Science December 2006, Vol.47, 5227-5233. doi:10.1167/iovs.05-1513
The Effect of Lutein and Zeaxanthin Supplementation on Metabolites of These Carotenoids in the Serum of Persons Aged 60 or Older Free
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Frederick Khachik; Fabiana F. de Moura; Emily Y. Chew; Larry W. Douglass; Frederick L. Ferris, III; Jonghyeon Kim; Darby J. S. Thompson
Tags: carotenoids, lutein, metabolites
Investigative Ophthalmology & Visual Science December 2006, Vol.47, 5234-5242. doi:10.1167/iovs.06-0504

Cornea

Expression of VSX1 in Human Corneal Keratocytes during Differentiation into Myofibroblasts in Response to Wound Healing Free
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Vanessa Barbaro; Enzo Di Iorio; Stefano Ferrari; Luigi Bisceglia; Alessandro Ruzza; Michele De Luca; Graziella Pellegrini
Tags: cornea, keratocytes, myofibroblasts, wound healing
Investigative Ophthalmology & Visual Science December 2006, Vol.47, 5243-5250. doi:10.1167/iovs.06-0185
Multiphoton Fluorescence and Second Harmonic Generation Imaging of the Structural Alterations in Keratoconus Ex Vivo Free
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Hsin-Yuan Tan; Yen Sun; Wen Lo; Sung-Jan Lin; Ching-Hsi Hsiao; Yeong-Fong Chen; Samuel Chao-Ming Huang; Wei-Chou Lin; Shiou-Hwa Jee; Hsin-Su Yu; Chen-Yuan Dong
Tags: diagnostic imaging, fluorescence, keratoconus, harmonics, cornea
Investigative Ophthalmology & Visual Science December 2006, Vol.47, 5251-5259. doi:10.1167/iovs.06-0386
Stimulation of Collagen Synthesis by Insulin and Proteoglycan Accumulation by Ascorbate in Bovine Keratocytes In Vitro Free
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Kurt Musselmann; Bradley Kane; Bridgette Alexandrou; John R. Hassell
Tags: cattle, collagen, collagen synthesis, insulin, keratocytes
Investigative Ophthalmology & Visual Science December 2006, Vol.47, 5260-5266. doi:10.1167/iovs.06-0612
Phosphatase-Mediated Crosstalk Control of ERK and p38 MAPK Signaling in Corneal Epithelial Cells Free
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