Volume 47 Issue 9 | IOVS

Clinical and Cytogenetic Analyses in Uveal Melanoma Free

Emine Kilic; Walter van Gils; Elisabeth Lodder; H. Berna Beverloo; Marjan E. van Til; Cornelia M. Mooy; Dion Paridaens; Annelies de Klein; Gregorius P. M. Luyten

Tags: cytogenetic analysis, intraocular melanoma, neoplasms, histopathology tests, chromosome abnormality

Investigative Ophthalmology & Visual Science September 2006, Vol.47, 3703-3707. doi:https://doi.org/10.1167/iovs.06-0101

Mitochondria as the Primary Target of Resveratrol-Induced Apoptosis in Human Retinoblastoma Cells Free

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Dhruv Sareen; Paul R. van Ginkel; Jennifer C. Takach; Ayesha Mohiuddin; Soesiawati R. Darjatmoko; Daniel M. Albert; Arthur S. Polans

Tags: apoptosis, mitochondria, resveratrol, retinoblastoma, cytochrome c

Investigative Ophthalmology & Visual Science September 2006, Vol.47, 3708-3716. doi:https://doi.org/10.1167/iovs.06-0119

Iontophoretic Delivery of Carboplatin in a Murine Model of Retinoblastoma Free

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Brandy Hayden; Maria-Elena Jockovich; Timothy G. Murray; Martina T. Kralinger; Monika Voigt; Eleut Hernandez; William Feuer; Jean-Marie Parel

Tags: carboplatin, retinoblastoma, neoplasms, eye

Investigative Ophthalmology & Visual Science September 2006, Vol.47, 3717-3721. doi:https://doi.org/10.1167/iovs.06-0365

Biochemistry and Molecular Biology

Heterologous Expression of Bovine Rhodopsin in Drosophila Photoreceptor Cells Free

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Syed Tariq Ahmad; Michael Natochin; Brandy Barren; Nikolai O. Artemyev; Joseph E. O’Tousa

Tags: drosophila, photoreceptors, rhodopsin, cattle, diptera

Investigative Ophthalmology & Visual Science September 2006, Vol.47, 3722-3728. doi:https://doi.org/10.1167/iovs.06-0281

Analysis of CFH, TLR4, and APOE Polymorphism in India Suggests the Tyr402His Variant of CFH to be a Global Marker for Age-Related Macular Degeneration Free

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Inderjeet Kaur; Avid Hussain; Nazimul Hussain; Taraprasad Das; Avinash Pathangay; Annie Mathai; Anjli Hussain; Rishita Nutheti; Praveen K. Nirmalan; Subhabrata Chakrabarti

Tags: age-related macular degeneration, apolipoprotein e, india, polymorphism, single nucleotide polymorphism

Investigative Ophthalmology & Visual Science September 2006, Vol.47, 3729-3735. doi:https://doi.org/10.1167/iovs.05-1430

CRB1 Heterozygotes with Regional Retinal Dysfunction: Implications for Genetic Testing of Leber Congenital Amaurosis Free

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Suzanne Yzer; Gerald A. Fishman; Julie Racine; Sana Al-Zuhaibi; Hadi Chakor; Allison Dorfman; Janet Szlyk; Pierre Lachapelle; L. Ingeborgh van den Born; Rando Allikmets; Irma Lopez; Frans P. M. Cremers; Robert K. Koenekoop

Tags: family, genetic screening, heterozygote, leber's amaurosis, macular disorders

Investigative Ophthalmology & Visual Science September 2006, Vol.47, 3736-3744. doi:https://doi.org/10.1167/iovs.05-1637

Light-Driven Cone Arrestin Translocation in Cones of Postnatal Guanylate Cyclase-1 Knockout Mouse Retina Treated with AAV-GC1 Free

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Shannon E. Haire; Jijing Pang; Sanford L. Boye; Izabel Sokal; Cheryl M. Craft; Krzysztof Palczewski; William W. Hauswirth; Susan L. Semple-Rowland

Tags: arrestin, mice, retina, retinal cone, translocation (genetics)

Investigative Ophthalmology & Visual Science September 2006, Vol.47, 3745-3753. doi:https://doi.org/10.1167/iovs.06-0086

Why Do Mutations in the Ubiquitously Expressed Housekeeping Gene IMPDH1 Cause Retina-Specific Photoreceptor Degeneration? Free

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Sara J. Bowne; Qin Liu; Lori S. Sullivan; Jingya Zhu; Catherine J. Spellicy; Catherine Bowes Rickman; Eric A. Pierce; Stephen P. Daiger

Tags: genes, mice, mutation, photoreceptors, protein isoforms

Investigative Ophthalmology & Visual Science September 2006, Vol.47, 3754-3765. doi:https://doi.org/10.1167/iovs.06-0207

Clinical and Epidemiologic Research

Influence of Tamsulosin on the Iris and Its Implications for Cataract Surgery Free

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Olavi Pärssinen; Esa Leppänen; Pekka Keski-Rahkonen; Timo Mauriala; Benoit Dugué; Marko Lehtonen

Tags: cataract surgery, immune reconstitution inflammatory syndrome, iris, tamsulosin, pupil

Investigative Ophthalmology & Visual Science September 2006, Vol.47, 3766-3771. doi:https://doi.org/10.1167/iovs.06-0153

Atherosclerosis, C-Reactive Protein, and Risk for Open-Angle Glaucoma: The Rotterdam Study Free

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Simone de Voogd; Roger C. W. Wolfs; Nomdo M. Jansonius; Jacqueline C. M. Witteman; Albert Hofman; Paulus T. V. M. de Jong

Tags: atherosclerosis, c-reactive protein, open-angle glaucoma

Investigative Ophthalmology & Visual Science September 2006, Vol.47, 3772-3776. doi:https://doi.org/10.1167/iovs.05-1278

Mutational Screening of the RP2 and RPGR Genes in Spanish Families with X-Linked Retinitis Pigmentosa Free

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Maria García-Hoyos; Blanca Garcia-Sandoval; Diego Cantalapiedra; Rosa Riveiro; Isabel Lorda-Sánchez; Maria Jose Trujillo-Tiebas; Marta Rodriguez de Alba; Jose Maria Millan; Monserrat Baiget; Carmen Ramos; Carmen Ayuso

Tags: family, genes, mutation, retinitis pigmentosa, screening

Investigative Ophthalmology & Visual Science September 2006, Vol.47, 3777-3782. doi:https://doi.org/10.1167/iovs.06-0323

Lutein and Zeaxanthin and the Risk of Cataract: The Melbourne Visual Impairment Project Free

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Hien T. V. Vu; Luba Robman; Allison Hodge; Catherine A. McCarty; Hugh R. Taylor

Tags: cataract, lutein, visual impairment, cataract, nuclear

Investigative Ophthalmology & Visual Science September 2006, Vol.47, 3783-3786. doi:https://doi.org/10.1167/iovs.05-0587

Cornea

No Pathogenic Mutations Identified in the COL8A1 and COL8A2 Genes in Familial Fuchs Corneal Dystrophy Free

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Anthony J. Aldave; Sylvia A. Rayner; Andrew K. Salem; Gina L. Yoo; Brian T. Kim; Monika Saeedian; Baris Sonmez; Vivek S. Yellore

Tags: genes, hereditary corneal dystrophy, mutation, family, dna

Investigative Ophthalmology & Visual Science September 2006, Vol.47, 3787-3790. doi:https://doi.org/10.1167/iovs.05-1635

Two-Stage Genome-Wide Linkage Scan in Keratoconus Sib Pair Families Free

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Xiaohui Li; Yaron S. Rabinowitz; Yongming G. Tang; Yoana Picornell; Kent D. Taylor; Mingshu Hu; Huiying Yang

Tags: family, genome, keratoconus, chromosomes

Investigative Ophthalmology & Visual Science September 2006, Vol.47, 3791-3795. doi:https://doi.org/10.1167/iovs.06-0214

Inhibition by Triptolide of Chemokine, Proinflammatory Cytokine, and Adhesion Molecule Expression Induced by Lipopolysaccharide in Corneal Fibroblasts Free

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Ying Lu; Yang Liu; Ken Fukuda; Yoshikuni Nakamura; Naoki Kumagai; Teruo Nishida

Tags: cell adhesion molecules, chemokines, cornea, cytokine, dexamethasone

Investigative Ophthalmology & Visual Science September 2006, Vol.47, 3796-3800. doi:https://doi.org/10.1167/iovs.06-0319

Serial Analysis of Gene Expression (SAGE) in the Rat Limbal and Central Corneal Epithelium Free

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Wakako Adachi; Hagit Ulanovsky; Yan Li; Barbara Norman; Janine Davis; Joram Piatigorsky

Tags: cornea, corneal epithelium, proteins, serial analysis of gene expression, libraries

Investigative Ophthalmology & Visual Science September 2006, Vol.47, 3801-3810. doi:https://doi.org/10.1167/iovs.06-0216

Defensins HNP1 and HBD2 Stimulation of Wound-Associated Responses in Human Conjunctival Fibroblasts Free

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Jing Li; Michael Raghunath; Donald Tan; Ricky R. Lareu; ZhenCheng Chen; Roger W. Beuerman

Tags: conjunctiva, defb4 gene, defensins, fibroblasts, collagen

Investigative Ophthalmology & Visual Science September 2006, Vol.47, 3811-3819. doi:https://doi.org/10.1167/iovs.05-1360

Establishment of a Cultivated Human Conjunctival Epithelium as an Alternative Tissue Source for Autologous Corneal Epithelial Transplantation Free

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Hidetoshi Tanioka; Satoshi Kawasaki; Kenta Yamasaki; Leonard P. K. Ang; Noriko Koizumi; Takahiro Nakamura; Norihiko Yokoi; Aoi Komuro; Tsutomu Inatomi; Shigeru Kinoshita

Tags: body tissue, conjunctival epithelium, cornea, epithelium, transplantation

Investigative Ophthalmology & Visual Science September 2006, Vol.47, 3820-3827. doi:https://doi.org/10.1167/iovs.06-0293

Eye Movements, Strabismus, Amblyopia and Neuro-ophthalmology

Identification of Acetylcholine Receptor Subunits Differentially Expressed in Singly and Multiply Innervated Fibers of Extraocular Muscles Free

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Sven Fraterman; Tejvir S. Khurana; Neal A. Rubinstein

Tags: adult, cholinergic receptors, muscle of orbit, muscle, myogenin

Investigative Ophthalmology & Visual Science September 2006, Vol.47, 3828-3834. doi:https://doi.org/10.1167/iovs.06-0073

Glaucoma

Potential Role of Tissue Transglutaminase in Glaucoma Filtering Surgery Free

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Siegfried G. Priglinger; Claudia S. Alge; Daniel Kook; Martin Thiel; Ricarda Schumann; Kirsten Eibl; Alice Yu; Aljoscha S. Neubauer; Anselm Kampik; Ulrich Welge-Lussen

Tags: blister, body tissue, cell culture techniques, cicatrix, fibronectins

Investigative Ophthalmology & Visual Science September 2006, Vol.47, 3835-3845. doi:https://doi.org/10.1167/iovs.05-0960

Novel Mutations of FOXC1 and PITX2 in Patients with Axenfeld-Rieger Malformations Free

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Nicole Weisschuh; Paul Dressler; Frank Schuettauf; Christiane Wolf; Bernd Wissinger; Eugen Gramer

Tags: congenital abnormality, mutation, genes, nucleotides

Investigative Ophthalmology & Visual Science September 2006, Vol.47, 3846-3852. doi:https://doi.org/10.1167/iovs.06-0343

Evoked Expression of the Glutamate Transporter GLT-1c in Retinal Ganglion Cells in Human Glaucoma and in a Rat Model Free

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Robert K. P. Sullivan; Elizabeth WoldeMussie; Lauren Macnab; Guadalupe Ruiz; David V. Pow

Tags: glaucoma, glutamate, glutamates, membrane transport proteins, retinal ganglion cells

Investigative Ophthalmology & Visual Science September 2006, Vol.47, 3853-3859. doi:https://doi.org/10.1167/iovs.06-0231

Pressure-Induced Regulation of IL-6 in Retinal Glial Cells: Involvement of the Ubiquitin/Proteasome Pathway and NFκB Free

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Rebecca M. Sappington; David J. Calkins

Tags: interleukin-6, microglia, neuroglia, regulation, astrocytes

Investigative Ophthalmology & Visual Science September 2006, Vol.47, 3860-3869. doi:https://doi.org/10.1167/iovs.05-1408

Enhanced Imaging Algorithm for Scanning Laser Polarimetry with Variable Corneal Compensation Free

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Nicolaas J. Reus; Qienyuan Zhou; Hans G. Lemij

Tags: cornea, diagnostic imaging, eye, glaucoma, scanning laser polarimetry

Investigative Ophthalmology & Visual Science September 2006, Vol.47, 3870-3877. doi:https://doi.org/10.1167/iovs.05-0067

Biochemical Activity of Reactive Oxygen Species Scavengers Do Not Predict Retinal Ganglion Cell Survival Free

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Christopher R. Schlieve; Christopher J. Lieven; Leonard A. Levin

Tags: gas scavengers, paraquat, reactive oxygen species, retinal ganglion cells, superoxides

Investigative Ophthalmology & Visual Science September 2006, Vol.47, 3878-3886. doi:https://doi.org/10.1167/iovs.05-1010

Effect of Latanoprost on the Expression of Matrix Metalloproteinases and Their Tissue Inhibitors in Human Trabecular Meshwork Cells Free

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Dong-Jin Oh; Jonathan L. Martin; Adrienne J. Williams; Paul Russell; David E. Birk; Douglas J. Rhee

Tags: body tissue, latanoprost, matrix metalloproteinases, rna, messenger

Investigative Ophthalmology & Visual Science September 2006, Vol.47, 3887-3895. doi:https://doi.org/10.1167/iovs.06-0036

Asymmetries and Visual Field Summaries as Predictors of Glaucoma in the Ocular Hypertension Treatment Study Free

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Richard A. Levine; Shaban Demirel; Juanjuan Fan; John L. Keltner; Chris A. Johnson; Michael A. Kass; the Ocular Hypertension Treatment Study Group

Tags: eye, glaucoma, ocular hypertension, open-angle glaucoma, visual fields

Investigative Ophthalmology & Visual Science September 2006, Vol.47, 3896-3903. doi:https://doi.org/10.1167/iovs.05-0469

The Relationship between Retinal Ganglion Cell Function and Retinal Nerve Fiber Thickness in Early Glaucoma Free

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Lori M. Ventura; Nancy Sorokac; Roosevelt De Los Santos; William J. Feuer; Vittorio Porciatti

Tags: glaucoma, retinal nerve fiber layer, retinal ganglion cells, nerve fibers, electromyography

Investigative Ophthalmology & Visual Science September 2006, Vol.47, 3904-3911. doi:https://doi.org/10.1167/iovs.06-0161

Immunology and Microbiology

Pigment Epithelial Growth Factor Suppresses Inflammation by Modulating Macrophage Activation Free

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Parisa Zamiri; Sharmila Masli; J. Wayne Streilein; Andrew W. Taylor

Tags: antibodies, epithelium, growth factor, inflammation, interleukin-10

Investigative Ophthalmology & Visual Science September 2006, Vol.47, 3912-3918. doi:https://doi.org/10.1167/iovs.05-1267

A Common Locus for Late-Onset Fuchs Corneal Dystrophy Maps to 18q21.2-q21.32 Free

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Olof H. Sundin; Karl W. Broman; Howard H. Chang; Elizabeth C. L. Vito; Walter J. Stark; John D. Gottsch

Tags: family, hereditary corneal dystrophy, maps, haplotypes, genetic linkage analysis

Investigative Ophthalmology & Visual Science September 2006, Vol.47, 3919-3926. doi:https://doi.org/10.1167/iovs.05-1619

Hemorheologic Abnormalities Associated with HIV Infection: Altered Erythrocyte Aggregation and Deformability Free

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Alisa Kim; Hajir Dadgostar; Gary N. Holland; Rosalinda Wenby; Fei Yu; Brian G. Terry; Herbert J. Meiselman

Tags: erythrocyte aggregation measurement, hiv, hiv infections, erythrocyte deformability, anti-retroviral agents

Investigative Ophthalmology & Visual Science September 2006, Vol.47, 3927-3932. doi:https://doi.org/10.1167/iovs.06-0137

Hemorheologic Abnormalities Associated with HIV Infection: In Vivo Assessment of Retinal Microvascular Blood Flow Free

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Hajir Dadgostar; Gary N. Holland; Xin Huang; Adnan Tufail; Alisa Kim; Timothy C. Fisher; William G. Cumberland; Herbert J. Meiselman; Arthur Benjamin; Dirk-Uwe Bartsch

Tags: fluid flow, hiv, hiv infections, vascular flow, retina

Investigative Ophthalmology & Visual Science September 2006, Vol.47, 3933-3938. doi:https://doi.org/10.1167/iovs.06-0138

Identification of MHC Class I H-2 K^b/D^b-Restricted Immunogenic Peptides Derived from Retinal Proteins Free

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Mingjun Wang; Fang Bai; Mette Pries; Søren Buus; Jan U. Prause; Mogens H. Nissen

Tags: peptides, proteins, immunization, genes, mhc class i

Investigative Ophthalmology & Visual Science September 2006, Vol.47, 3939-3945. doi:https://doi.org/10.1167/iovs.06-0133

Interferon-α: A Key Factor in Autoimmune Disease? Free

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Jarka Plskova; Kathrin Greiner; Elizabeth Muckersie; Linda Duncan; John V. Forrester

Tags: autoimmune diseases, dendritic cells, interferons, t-lymphocytes, uveitis

Investigative Ophthalmology & Visual Science September 2006, Vol.47, 3946-3950. doi:https://doi.org/10.1167/iovs.06-0058

Lens

The Unfolded Protein Response in Lens Epithelial Cells from Galactosemic Rat Lenses Free

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Michael L. Mulhern; Christian J. Madson; Andrew Danford; Kengo Ikesugi; Peter F. Kador; Toshimichi Shinohara

Tags: galactose, glucose, lens (device), lens, crystalline, proteins

Investigative Ophthalmology & Visual Science September 2006, Vol.47, 3951-3959. doi:https://doi.org/10.1167/iovs.06-0193

Accelerated Cataract Formation and Reduced Lens Epithelial Water Permeability in Aquaporin-1-Deficient Mice Free

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Javier Ruiz-Ederra; A. S. Verkman

Tags: aquaporin 1, cataract, lens (device), lens, crystalline, mice

Investigative Ophthalmology & Visual Science September 2006, Vol.47, 3960-3967. doi:https://doi.org/10.1167/iovs.06-0229

Physiology and Pharmacology

Effect of Subconjunctivally Injected, Liposome-Bound, Low-Molecular-Weight Heparin on the Absorption Rate of Subconjunctival Hemorrhage in Rabbits Free

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Jun-Woong Moon; Yun-Kyoung Song; Jun-Pil Jee; Chong-Kook Kim; Ho-Kyung Choung; Jeong-Min Hwang

Tags: liposomes, low-molecular-weight heparin, process of absorption, subconjunctival hemorrhage, oryctolagus cuniculus

Investigative Ophthalmology & Visual Science September 2006, Vol.47, 3968-3974. doi:https://doi.org/10.1167/iovs.05-1345

Metallothionein, an Endogenous Antioxidant, Protects against Retinal Neuron Damage in Mice Free

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Shinsuke Suemori; Masamitsu Shimazawa; Kazuhide Kawase; Masahiko Satoh; Hisamitsu Nagase; Tetsuya Yamamoto; Hideaki Hara

Tags: antioxidants, metallothionein, mice, neurons, n-methylaspartate

Investigative Ophthalmology & Visual Science September 2006, Vol.47, 3975-3982. doi:https://doi.org/10.1167/iovs.06-0275

Cyclosporine-Loaded Microspheres for Treatment of Uveitis: In Vitro Characterization and In Vivo Pharmacokinetic Study Free

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Yuan He; Yuling Liu; Yu Liu; Jiancheng Wang; Xuan Zhang; Wanliang Lu; Zhizhong Ma; Xiuan Zhu; Qiang Zhang

Tags: cysteine, microspheres, uveitis, cyclosporine

Investigative Ophthalmology & Visual Science September 2006, Vol.47, 3983-3988. doi:https://doi.org/10.1167/iovs.05-1373

PKC Isoform–Specific Enhancement of Capacitative Calcium Entry in Human Corneal Epithelial Cells Free

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Fan Zhang; Quan Wen; Stefan Mergler; Hua Yang; Zheng Wang; Victor N. Bildin; Peter S. Reinach

Tags: calcium, phorbol 12,13-dibutyrate, protein isoforms, corneal epithelial cells, rna, small interfering

Investigative Ophthalmology & Visual Science September 2006, Vol.47, 3989-4000. doi:https://doi.org/10.1167/iovs.06-0253

Human Trabecular Meshwork Cells Express Functional Serotonin-2A (5HT_2A) Receptors: Role in IOP Reduction Free

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Najam A. Sharif; Curtis R. Kelly; Marsha McLaughlin

Tags: agonists, intraocular pressure, serotonin, trabecular meshwork, donors

Investigative Ophthalmology & Visual Science September 2006, Vol.47, 4001-4010. doi:https://doi.org/10.1167/iovs.06-0062

Histamine-Induced Phosphorylation of the Regulatory Light Chain of Myosin II Disrupts the Barrier Integrity of Corneal Endothelial Cells Free

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Sangly P. Srinivas; Minati Satpathy; Ying Guo; Vasuki Anandan

Tags: histamine, personal integrity, phosphorylation, antigens, cd98 light chains, cornea

Investigative Ophthalmology & Visual Science September 2006, Vol.47, 4011-4018. doi:https://doi.org/10.1167/iovs.05-1127

On Pulse-Wave Propagation in the Ocular Circulation Free

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Konstantin Gugleta; Asan Kochkorov; Robert Katamay; Claudia Zawinka; Josef Flammer; Selim Orgul

Tags: arteriole, choroid, cold sensation, cold temperature, common cold

Investigative Ophthalmology & Visual Science September 2006, Vol.47, 4019-4025. doi:https://doi.org/10.1167/iovs.06-0168

Short-Term Retinal Vessel Diameter Variability in Relation to the History of Cold Extremities Free

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Asan Kochkorov; Konstantin Gugleta; Claudia Zawinka; Robert Katamay; Josef Flammer; Selim Orgul

Tags: cold sensation, cold temperature, common cold, diameter, limb

Investigative Ophthalmology & Visual Science September 2006, Vol.47, 4026-4033. doi:https://doi.org/10.1167/iovs.06-0177

Analysis of Retinal Vasodilation after Flicker Light Stimulation in Relation to Vasospastic Propensity Free

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Konstantin Gugleta; Claudia Zawinka; Ines Rickenbacher; Asan Kochkorov; Robert Katamay; Josef Flammer; Selim Orgul

Tags: dilatation, pathologic, photopsia, diameter, vasodilation

Investigative Ophthalmology & Visual Science September 2006, Vol.47, 4034-4041. doi:https://doi.org/10.1167/iovs.06-0351

The Prostanoid EP₂ Receptor Agonist Butaprost Increases Uveoscleral Outflow in the Cynomolgus Monkey Free

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Siv F. E. Nilsson; Enken Drecoll; Elke Lütjen-Drecoll; Carol B. Toris; Achim H.-P. Krauss; Alexander Kharlamb; Amelia Nieves; Teresa Guerra; David F. Woodward

Tags: agonists, aqueous humor, eye, intraocular pressure, macaca fascicularis

Investigative Ophthalmology & Visual Science September 2006, Vol.47, 4042-4049. doi:https://doi.org/10.1167/iovs.05-1627

Circadian Intraocular Pressure Rhythm Is Generated by Clock Genes Free

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Ari Maeda; Sosuke Tsujiya; Tomomi Higashide; Kazunori Toida; Takeshi Todo; Tomoko Ueyama; Hitoshi Okamura; Kazuhisa Sugiyama

Tags: clock gene, intraocular pressure, rhythm, mice

Investigative Ophthalmology & Visual Science September 2006, Vol.47, 4050-4052. doi:https://doi.org/10.1167/iovs.06-0183

Increased Levels of Diadenosine Polyphosphates in Dry Eye Free

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Assumpta Peral; Gonzalo Carracedo; M. Carmen Acosta; Juana Gallar; Jesús Pintor

Tags: dry eye syndromes, polyphosphates, bodily secretions, blinking

Investigative Ophthalmology & Visual Science September 2006, Vol.47, 4053-4058. doi:https://doi.org/10.1167/iovs.05-0980

Retina

Vascular Endothelial Growth Factor Upregulates Expression of ADAMTS1 in Endothelial Cells through Protein Kinase C Signaling Free

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Zhenhua Xu; Yilin Yu; Elia J. Duh

Tags: endothelial cells, vascular endothelial growth factor a, protein kinase c, rna, messenger, signal transduction

Investigative Ophthalmology & Visual Science September 2006, Vol.47, 4059-4066. doi:https://doi.org/10.1167/iovs.05-1528

Plasma Homocysteine and Cysteine Levels in Retinal Vein Occlusion Free

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Antonio Pinna; Ciriaco Carru; Angelo Zinellu; Stefano Dore; Luca Deiana; Francesco Carta

Tags: cysteine, homocysteine, retinal vein occlusion

Investigative Ophthalmology & Visual Science September 2006, Vol.47, 4067-4071. doi:https://doi.org/10.1167/iovs.06-0290

Oxygen Distribution and Consumption in the Developing Rat Retina Free

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Stephen J. Cringle; Paula K. Yu; Er-Ning Su; Dao-Yi Yu

Tags: oxygen, retina, rats, oxygen consumption

Investigative Ophthalmology & Visual Science September 2006, Vol.47, 4072-4076. doi:https://doi.org/10.1167/iovs.05-1638

α-Lipoic Acid Corrects Late-Phase Supernormal Retinal Oxygenation Response in Experimental Diabetic Retinopathy Free

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Robin Roberts; Hongmei Luan; Bruce A. Berkowitz

Tags: alveolar ventilation function, cell respiration, diabetes mellitus, diabetic retinopathy, magnetic resonance imaging

Investigative Ophthalmology & Visual Science September 2006, Vol.47, 4077-4082. doi:https://doi.org/10.1167/iovs.06-0464

Gene Transfer to Rabbit Retina with Electron Avalanche Transfection Free

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Thomas W. Chalberg; Alexander Vankov; Fanni E. Molnar; Alexander F. Butterwick; Philip Huie; Michele P. Calos; Daniel V. Palanker

Tags: electroporation, gene transfer techniques, oryctolagus cuniculus, retina, transfection

Investigative Ophthalmology & Visual Science September 2006, Vol.47, 4083-4090. doi:https://doi.org/10.1167/iovs.06-0092

Complement Factor H: Spatial and Temporal Expression and Localization in the Eye Free

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Nawajes A. Mandal; Radha Ayyagari

Tags: body tissue, complement factor h, eye, mice, proteins

Investigative Ophthalmology & Visual Science September 2006, Vol.47, 4091-4097. doi:https://doi.org/10.1167/iovs.05-1655

Repetitive Nonlethal Oxidant Injury to Retinal Pigment Epithelium Decreased Extracellular Matrix Turnover In Vitro and Induced Sub-RPE Deposits In Vivo Free

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Maria E. Marin-Castaño; Gary E. Striker; Oscar Alcazar; Paola Catanuto; Diego G. Espinosa-Heidmann; Scott W. Cousins

Tags: gelatinase a, oxidants, wounds and injuries, proteins, collagen type iv

Investigative Ophthalmology & Visual Science September 2006, Vol.47, 4098-4112. doi:https://doi.org/10.1167/iovs.05-1230

Remodeling of the Human Retina in Choroideremia: Rab Escort Protein 1 (REP-1) Mutations Free

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Samuel G. Jacobson; Artur V. Cideciyan; Alexander Sumaroka; Tomas S. Aleman; Sharon B. Schwartz; Elizabeth A. M. Windsor; Alejandro J. Roman; Edwin M. Stone; Ian M. MacDonald

Tags: choroideremia, mutation, proteins, retina, photoreceptors

Investigative Ophthalmology & Visual Science September 2006, Vol.47, 4113-4120. doi:https://doi.org/10.1167/iovs.06-0424

Retinal Cell Biology

Adenovirally Transduced Bone Marrow Stromal Cells Differentiate into Pigment Epithelial Cells and Induce Rescue Effects in RCS Rats Free

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Stefan Arnhold; Peter Heiduschka; Helmut Klein; Yvonne Absenger; Serkan Basnaoglu; Florian Kreppel; Sylvia Henke-Fahle; Stefan Kochanek; Karl-Ulrich Bartz-Schmidt; Klaus Addicks; Ulrich Schraermeyer

Tags: bone marrow, epithelial cells, mesenchymal stem cells, photoreceptors, pigment

Investigative Ophthalmology & Visual Science September 2006, Vol.47, 4121-4129. doi:https://doi.org/10.1167/iovs.04-1501

Elevated Glucose Changes the Expression of Ionotropic Glutamate Receptor Subunits and Impairs Calcium Homeostasis in Retinal Neural Cells Free

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Ana R. Santiago; Susana C. Rosa; Paulo F. Santos; Armando J. Cristóvão; Alistair J. Barber; António F. Ambrósio

Tags: ampa receptors, calcium ion homeostasis, glucose, glutamate receptors, hyperglycemia

Investigative Ophthalmology & Visual Science September 2006, Vol.47, 4130-4137. doi:https://doi.org/10.1167/iovs.06-0085

Small Molecule Anti-Angiogenic Probes of the Ubiquitin Proteasome Pathway: Potential Application to Choroidal Neovascularization Free

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Paola Bargagna-Mohan; Padma Priya Ravindranath; Royce Mohan

Tags: angiogenesis, choroidal neovascularization, endothelial cells, small molecule, ubiquitin-proteasome proteolytic pathway

Investigative Ophthalmology & Visual Science September 2006, Vol.47, 4138-4145. doi:https://doi.org/10.1167/iovs.05-1452

Visual Psychophysics and Physiological Optics

Object Localization in Blurred and Jumbled Scenes: Differences between Myopic and Emmetropic Observers Free

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Guillaume Giraudet; Laure Azavant

Tags: adaptability, decision making, frequency of responses, learning, natural scenes

Investigative Ophthalmology & Visual Science September 2006, Vol.47, 4146-4151. doi:https://doi.org/10.1167/iovs.05-0430

Use of an Augmented-Vision Device for Visual Search by Patients with Tunnel Vision Free

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Gang Luo; Eli Peli

Tags: bilateral visual field constriction, gaze, vision, visual search, cues

Investigative Ophthalmology & Visual Science September 2006, Vol.47, 4152-4159. doi:https://doi.org/10.1167/iovs.05-1672

Retinal Microscotomas Revealed with Adaptive-Optics Microflashes Free

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Walter Makous; Joseph Carroll; Jessica I. Wolfing; Julianna Lin; Nathan Christie; David R. Williams

Tags: mosaicism, optics, retinal cone, exanthema, retina

Investigative Ophthalmology & Visual Science September 2006, Vol.47, 4160-4167. doi:https://doi.org/10.1167/iovs.05-1195

Diurnal Fluctuations and Developmental Changes in Ocular Dimensions and Optical Aberrations in Young Chicks Free

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Yibin Tian; Christine F. Wildsoet

Tags: eye, optics, refractive errors, surgical procedures, operative

Investigative Ophthalmology & Visual Science September 2006, Vol.47, 4168-4178. doi:https://doi.org/10.1167/iovs.05-1211

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