Volume 48 Issue 5 | IOVS

Anatomy and Pathology/Oncology

Morphometry of the Retrobulbar Human Optic Nerve: Comparison between Conventional Sonography and Ultrafast Magnetic Resonance Sequences Free

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Wolf A. Lagrèze; Alexander Lazzaro; Matthias Weigel; Hans-Christian Hansen; Jürgen Hennig; Thorsten A. Bley

Tags: optic nerve, ultrasonography, vibration, magnetic resonance imaging

Investigative Ophthalmology & Visual Science May 2007, Vol.48, 1913-1917. doi:https://doi.org/10.1167/iovs.06-1075

The Spatial Distribution of Monosomy 3 and Network Vasculogenic Mimicry Patterns in Uveal Melanoma Free

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Tal Meir; Michael Zeschnigk; Lars Maßhöfer; Jacob Pe’er; Itay Chowers

Tags: monosomy, neoplasms, uveal melanoma

Investigative Ophthalmology & Visual Science May 2007, Vol.48, 1918-1922. doi:https://doi.org/10.1167/iovs.06-1308

Histogenesis of the Intravitreal Membrane and Secondary Vitreous in the Mouse Free

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Masataka Ito; Misako Nakashima; Nobuo Tsuchida; Junko Imaki; Masahiko Yoshioka

Tags: histogenesis, lectin, mice, tissue membrane, vitreous body

Investigative Ophthalmology & Visual Science May 2007, Vol.48, 1923-1930. doi:https://doi.org/10.1167/iovs.06-0325

Biochemistry and Molecular Biology

Platelet-Activating Factor Overturns the Transcriptional Repressor Disposition of Sp1 in the Expression of MMP-9 in Human Corneal Epithelial Cells Free

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Faramarz Taheri; Haydee E. P. Bazan

Tags: gelatinase b, platelet activating factor, transcriptional repression, corneal epithelial cells, dna

Investigative Ophthalmology & Visual Science May 2007, Vol.48, 1931-1941. doi:https://doi.org/10.1167/iovs.06-1008

Increased Sensitivity to Light-Induced Damage in a Mouse Model of Autosomal Dominant Retinal Disease Free

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D. Alan White; William W. Hauswirth; Shalesh Kaushal; Alfred S. Lewin

Tags: electroretinography, light, lighting, mice, apoptosis

Investigative Ophthalmology & Visual Science May 2007, Vol.48, 1942-1951. doi:https://doi.org/10.1167/iovs.06-1131

Upregulation of TGF-β–Induced Tissue Transglutaminase Expression by PI3K-Akt Pathway Activation in Human Subconjunctival Fibroblasts Free

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Sun-Ah Jung; Hyung Keun Lee; Jin Sook Yoon; Sung-Joo Kim; Chan Yoon Kim; Heesang Song; Ki-Chul Hwang; Jong Bok Lee; Joon H. Lee

Tags: body tissue, fibroblasts, pi3k/akt signaling pathway, transglutaminases, up-regulation (physiology)

Investigative Ophthalmology & Visual Science May 2007, Vol.48, 1952-1958. doi:https://doi.org/10.1167/iovs.06-1164

Bestrophin Gene Mutations Cause Canine Multifocal Retinopathy: A Novel Animal Model for Best Disease Free

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Karina E. Guziewicz; Barbara Zangerl; Sarah J. Lindauer; Robert F. Mullins; Lynne S. Sandmeyer; Bruce H. Grahn; Edwin M. Stone; Gregory M. Acland; Gustavo D. Aguirre

Tags: animal model, dog, domestic, mutation, retinal diseases, vitelliform dystrophy

Investigative Ophthalmology & Visual Science May 2007, Vol.48, 1959-1967. doi:https://doi.org/10.1167/iovs.06-1374

Functional Comparisons of Visual Arrestins in Rod Photoreceptors of Transgenic Mice Free

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Sanny Chan; William W. Rubin; Ana Mendez; Xiao Liu; Xiufeng Song; Susan M. Hanson; Cheryl M. Craft; Vsevolod V. Gurevich; Marie E. Burns; Jeannie Chen

Tags: arrestin, arrestins, mice, transgenic, retinal cone, rod photoreceptors

Investigative Ophthalmology & Visual Science May 2007, Vol.48, 1968-1975. doi:https://doi.org/10.1167/iovs.06-1287

Clinical and Epidemiologic Research

Rasch Analysis of the Daily Living Tasks Dependent on Vision (DLTV) Free

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Frances Denny; Adele H. Marshall; Michael R. Stevenson; Patricia M. Hart; Usha Chakravarthy

Tags: rasch model, vision

Investigative Ophthalmology & Visual Science May 2007, Vol.48, 1976-1982. doi:https://doi.org/10.1167/iovs.06-0135

Circulating Inflammatory Markers and Hemostatic Factors in Age-Related Maculopathy: A Population-Based Case–Control Study Free

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Kathy H. C. Wu; Ava Grace Tan; Elena Rochtchina; Emmanuel J. Favaloro; Andrew Williams; Paul Mitchell; Jie Jin Wang

Tags: age-related macular degeneration, hemostatics, inflammatory markers, homocysteine, fibrinogen

Investigative Ophthalmology & Visual Science May 2007, Vol.48, 1983-1988. doi:https://doi.org/10.1167/iovs.06-0223

Knowledge, Attitudes, and Beliefs about Dilated Eye Examinations among African-Americans Free

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Nancy J. Ellish; Renee Royak-Schaler; Susan R. Passmore; Eve J. Higginbotham

Tags: african american, ophthalmic examination and evaluation, attitude, perception, glaucoma

Investigative Ophthalmology & Visual Science May 2007, Vol.48, 1989-1994. doi:https://doi.org/10.1167/iovs.06-0934

The Association between Retinal Vascular Network Geometry and Cognitive Ability in an Elderly Population Free

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Niall Patton; Alison Pattie; Tom MacGillivray; Tariq Aslam; Baljean Dhillon; Alan Gow; John M. Starr; Lawrence J. Whalley; Ian J. Deary

Tags: cognitive ability, older adult, vasculature, cognition, memory

Investigative Ophthalmology & Visual Science May 2007, Vol.48, 1995-2000. doi:https://doi.org/10.1167/iovs.06-1123

Cornea

Benzalkonium Chloride Induces Dephosphorylation of Myosin Light Chain in Cultured Corneal Epithelial Cells Free

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Ying Guo; Minati Satpathy; Graeme Wilson; Sangly P. Srinivas

Tags: actins, benzalkonium chloride, corneal epithelial cells, cytoskeleton, myosin light chain kinase

Investigative Ophthalmology & Visual Science May 2007, Vol.48, 2001-2008. doi:https://doi.org/10.1167/iovs.06-0613

Mitomycin C Upregulates IL-8 and MCP-1 Chemokine Expression via Mitogen-Activated Protein Kinases in Corneal Fibroblasts Free

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San-Fang Chou; Shu-Wen Chang; Jia-Ling Chuang

Tags: chemokines, cornea, fibroblasts, interleukin-8, mitogen-activated protein kinases

Investigative Ophthalmology & Visual Science May 2007, Vol.48, 2009-2016. doi:https://doi.org/10.1167/iovs.06-0835

The Cornea in Sjögren’s Syndrome: An In Vivo Confocal Study Free

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Edoardo Villani; Daniela Galimberti; Francesco Viola; Chiara Mapelli; Roberto Ratiglia

Tags: cornea, sjogren's syndrome, epithelium

Investigative Ophthalmology & Visual Science May 2007, Vol.48, 2017-2022. doi:https://doi.org/10.1167/iovs.06-1129

A Pharmacokinetic and Safety Evaluation of an Episcleral Cyclosporine Implant for Potential Use in High-Risk Keratoplasty Rejection Free

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Susan S. Lee; Hyuncheol Kim; Nam Sun Wang; Peter M. Bungay; Brian C. Gilger; Peng Yuan; Jonghyeon Kim; Karl G. Csaky; Michael R. Robinson

Tags: cyclosporine, implants, keratoplasty, rejection (psychology), pharmacokinetics

Investigative Ophthalmology & Visual Science May 2007, Vol.48, 2023-2029. doi:https://doi.org/10.1167/iovs.06-0985

Nanoparticles Sustain Expression of Flt Intraceptors in the Cornea and Inhibit Injury-Induced Corneal Angiogenesis Free

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Pooja D. Jani; Nirbhai Singh; Crystal Jenkins; Swita Raghava; Yun Mo; Shivan Amin; Uday B. Kompella; Balamurali K. Ambati

Tags: cornea, corneal neovascularization, nanoparticles, wounds and injuries, plasmids

Investigative Ophthalmology & Visual Science May 2007, Vol.48, 2030-2036. doi:https://doi.org/10.1167/iovs.06-0853

Photo Cross-linkable Biodendrimers as Ophthalmic Adhesives for Central Lacerations and Penetrating Keratoplasties Free

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Lovorka Degoricija; C. Starck Johnson; Michel Wathier; Terry Kim; Mark W. Grinstaff

Tags: adhesives, eye, keratoplasty, penetrating, lacerations, wounds and injuries

Investigative Ophthalmology & Visual Science May 2007, Vol.48, 2037-2042. doi:https://doi.org/10.1167/iovs.06-0957

Localization of ZO-1 in the Nucleolus of Corneal Fibroblasts Free

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Miriam Benezra; Roseanne S. Greenberg; Sandra K. Masur

Tags: cell nucleolus, cornea, fibroblasts, cell nucleus, oryctolagus cuniculus

Investigative Ophthalmology & Visual Science May 2007, Vol.48, 2043-2049. doi:https://doi.org/10.1167/iovs.06-0754

Comparative Analysis of Human Conjunctival and Corneal Epithelial Gene Expression with Oligonucleotide Microarrays Free

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Helen C. Turner; Murat T. Budak; M. A. Murat Akinci; J. Mario Wolosin

Tags: body tissue, conjunctiva, cornea, epithelium, gene expression

Investigative Ophthalmology & Visual Science May 2007, Vol.48, 2050-2061. doi:https://doi.org/10.1167/iovs.06-0998

Reproducibility of Endothelial Assessment during Corneal Organ Culture: Comparison of a Computer-Assisted Analyzer with Manual Methods Free

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Nilanjana Deb-Joardar; Gilles Thuret; Yann Gavet; Sophie Acquart; Olivier Garraud; Harald Egelhoffer; Philippe Gain

Tags: computers, cornea, endothelium, organ culture techniques, eye banks

Investigative Ophthalmology & Visual Science May 2007, Vol.48, 2062-2067. doi:https://doi.org/10.1167/iovs.06-1043

Corneal Femtosecond Laser Keratotomy Results in Isolated Stromal Injury and Favorable Wound-Healing Response Free

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Christian Meltendorf; Guido J. Burbach; Jens Bühren; Reinhold Bug; Christian Ohrloff; Thomas Deller

Tags: cornea, epithelium, femtosecond pulsed lasers, fibroblasts, keratocytes

Investigative Ophthalmology & Visual Science May 2007, Vol.48, 2068-2075. doi:https://doi.org/10.1167/iovs.06-1150

Eye Movements, Strabismus, Amblyopia and Neuro-ophthalmology

Shifts in Listing’s Plane Produced by Vertical Axis Rotation: Sustained Ocular Torsion Due to Semicircular Canal Stimulation Free

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Benjamin T. Crane; Jun-Ru Tian; Joseph L. Demer

Tags: musculoskeletal torsion, function, torsion, semicircular canal, eye, scanning laser polarimetry

Investigative Ophthalmology & Visual Science May 2007, Vol.48, 2076-2083. doi:https://doi.org/10.1167/iovs.06-1219

Screening and Treating Amblyopia: Are We Making a Difference? Free

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Yair Morad; Erez Bakshi; Avi Levin; Oren G. Binyamini; David Zadok; Isaac Avni; Yosefa Bar Dayan

Tags: amblyopia, screening

Investigative Ophthalmology & Visual Science May 2007, Vol.48, 2084-2088. doi:https://doi.org/10.1167/iovs.06-0089

Infantile Nystagmus Adapts to Visual Demand Free

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Debbie Wiggins; J. Margaret Woodhouse; Tom H. Margrain; Christopher M. Harris; Jonathan T. Erichsen

Tags: pathologic nystagmus, eye movement, waveforms

Investigative Ophthalmology & Visual Science May 2007, Vol.48, 2089-2094. doi:https://doi.org/10.1167/iovs.06-1108

Glaucoma

Prostaglandin FP Receptors Do Not Contribute to 24-hour Intraocular Pressure Variation in Mice Free

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Jonathan G. Crowston; Christy A. Morris; James D. Lindsey; Robert N. Weinreb

Tags: intraocular pressure, mice, prostaglandins

Investigative Ophthalmology & Visual Science May 2007, Vol.48, 2095-2098. doi:https://doi.org/10.1167/iovs.06-0516

Scanning Laser Polarimetry with Enhanced Corneal Compensation and Optical Coherence Tomography in Normal and Glaucomatous Eyes Free

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Mitra Sehi; Stephen Ume; David S. Greenfield; Advanced Imaging in Glaucoma Study Group

Tags: cornea, eye, glaucoma, optical coherence tomography, scanning laser polarimetry

Investigative Ophthalmology & Visual Science May 2007, Vol.48, 2099-2104. doi:https://doi.org/10.1167/iovs.06-1087

Influence of Actin Cytoskeletal Integrity on Matrix Metalloproteinase-2 Activation in Cultured Human Trabecular Meshwork Cells Free

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Krishna Sanka; Rupalatha Maddala; David L. Epstein; P. Vasantha Rao

Tags: actins, cytochalasin d, cytoskeleton, gelatinase a, latrunculin a

Investigative Ophthalmology & Visual Science May 2007, Vol.48, 2105-2114. doi:https://doi.org/10.1167/iovs.06-1089

Contrast Sensitivity Changes Due to Glaucoma and Normal Aging: Low-Spatial-Frequency Losses in Both Magnocellular and Parvocellular Pathways Free

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Allison M. McKendrick; Geoff P. Sampson; Mark J. Walland; David R. Badcock

Tags: aging, contrast sensitivity, glaucoma, spatial frequency

Investigative Ophthalmology & Visual Science May 2007, Vol.48, 2115-2122. doi:https://doi.org/10.1167/iovs.06-1208

Lack of Association between Interleukin-1 Gene Cluster Polymorphisms and Glaucoma in Chinese Subjects Free

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Alicia C. S. How; Tin Aung; Xinyi Chew; Victor H. K. Yong; Marcus C. C. Lim; Kelvin Y. C. Lee; Ju-Yuan Toh; Yuqing Li; Jianjun Liu; Eranga N. Vithana

Tags: chinese (other dialects), chinese people, gene clusters, glaucoma, interleukin-1

Investigative Ophthalmology & Visual Science May 2007, Vol.48, 2123-2126. doi:https://doi.org/10.1167/iovs.06-1213

Effect of Ocular Hypertension on Retinal Nitridergic Pathway Activity Free

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Nicolás Belforte; María Cecilia Moreno; Cora Cymeryng; Melina Bordone; María Inés Keller Sarmiento; Ruth E. Rosenstein

Tags: arginine, eye, ocular hypertension, retina, cyclic gmp

Investigative Ophthalmology & Visual Science May 2007, Vol.48, 2127-2133. doi:https://doi.org/10.1167/iovs.06-1229

Connective Tissue Structure of the Tree Shrew Optic Nerve and Associated Ageing Changes Free

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Julie Albon; Sarah Farrant; Saeed Akhtar; Rob Young; Mike E. Boulton; Gillian Smith; Martin Taylor; Jez Guggenheim; James E. Morgan

Tags: connective tissue, optic nerve, tupaiidae, aging, optic disk

Investigative Ophthalmology & Visual Science May 2007, Vol.48, 2134-2144. doi:https://doi.org/10.1167/iovs.06-0084

Elevated Hydrostatic Pressure Triggers Mitochondrial Fission and Decreases Cellular ATP in Differentiated RGC-5 Cells Free

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Won-Kyu Ju; Quan Liu; Keun-Young Kim; Jonathan G. Crowston; James D. Lindsey; Neeraj Agarwal; Mark H. Ellisman; Guy A. Perkins; Robert N. Weinreb

Tags: hydrostatic pressure, mitochondria, precipitating factors

Investigative Ophthalmology & Visual Science May 2007, Vol.48, 2145-2151. doi:https://doi.org/10.1167/iovs.06-0573

The Rho-Kinase Inhibitor H-1152P Suppresses the Wound-Healing Activities of Human Tenon’s Capsule Fibroblasts In Vitro Free

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Aysegül Tura; Salvatore Grisanti; Katrin Petermeier; Sigrid Henke-Fahle

Tags: collagen, fibroblasts, phosphotransferases, tenon's capsule, gel

Investigative Ophthalmology & Visual Science May 2007, Vol.48, 2152-2161. doi:https://doi.org/10.1167/iovs.06-1271

Immunology and Microbiology

LYVE-1–Positive Macrophages Are Present in Normal Murine Eyes Free

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Heping Xu; Mei Chen; Delyth M. Reid; John V. Forrester

Tags: body tissue, bone marrow, conjunctiva, eye, flow cytometry

Investigative Ophthalmology & Visual Science May 2007, Vol.48, 2162-2171. doi:https://doi.org/10.1167/iovs.06-0783

Bacterial Transcytosis across Conjunctival M Cells Free

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Carisa K. Petris; Miriam Golomb; Thomas E. Phillips

Tags: bacteria, conjunctiva, microfold cell, transcytosis, hair follicle

Investigative Ophthalmology & Visual Science May 2007, Vol.48, 2172-2177. doi:https://doi.org/10.1167/iovs.06-1202

Minimally Activated CD8 Autoreactive T Cells Specific for IRBP Express a High Level of Foxp3 and Are Functionally Suppressive Free

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Yong Peng; Hui Shao; Yan Ke; Ping Zhang; Gencheng Han; Henry J. Kaplan; Deming Sun

Tags: foxp3 gene, t-lymphocytes, antigens

Investigative Ophthalmology & Visual Science May 2007, Vol.48, 2178-2184. doi:https://doi.org/10.1167/iovs.06-1189

Role of Anti–Glycoproteins D (Anti–gD) and K (Anti–gK) IgGs in Pathology of Herpes Stromal Keratitis in Humans Free

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Kevin R. Mott; Yanira Osorio; Ezra Maguen; Anthony B. Nesburn; Alec E. Wittek; Steve Cai; Subhendra Chattopadhyay; Homayon Ghiasi

Tags: antibodies, enzyme-linked immunosorbent assay, glycoproteins, grenada, human herpesvirus 1

Investigative Ophthalmology & Visual Science May 2007, Vol.48, 2185-2193. doi:https://doi.org/10.1167/iovs.06-1276

Modulation of CD8⁺ CTL Effector Function by Fibroblasts Derived from the Immunoprivileged Cornea Free

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Jared E. Knickelbein; Sherrie Divito; Robert L. Hendricks

Tags: clofibrate, cornea, cytotoxicity, fibroblasts, human herpesvirus 1

Investigative Ophthalmology & Visual Science May 2007, Vol.48, 2194-2202. doi:https://doi.org/10.1167/iovs.06-1321

Multiplex Bead Analysis of Vitreous Humor of Patients with Vitreoretinal Disorders Free

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Somnath Banerjee; Vijay Savant; Robert A. H. Scott; S. John Curnow; Graham R. Wallace; Philip I. Murray

Tags: cytokine, vitreoretinal disease, vitreous body, chemokines, growth factor

Investigative Ophthalmology & Visual Science May 2007, Vol.48, 2203-2207. doi:https://doi.org/10.1167/iovs.06-1358

Lens

Homozygous CRYBB1 Deletion Mutation Underlies Autosomal Recessive Congenital Cataract Free

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David Cohen; Udy Bar-Yosef; Jaime Levy; Libe Gradstein; Nadav Belfair; Rivka Ofir; Sarah Joshua; Tova Lifshitz; Rivka Carmi; Ohad S. Birk

Tags: autosomal recessive inheritance, congenital cataract, homozygote, mutation, genes

Investigative Ophthalmology & Visual Science May 2007, Vol.48, 2208-2213. doi:https://doi.org/10.1167/iovs.06-1019

Activation of Src Kinases Signals Induction of Posterior Capsule Opacification Free

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Janice L. Walker; Iris M. Wolff; Liping Zhang; A. Sue Menko

Tags: after-cataract, cataract surgery, chick embryo, epithelial to mesenchymal transition, lens (device)

Investigative Ophthalmology & Visual Science May 2007, Vol.48, 2214-2223. doi:https://doi.org/10.1167/iovs.06-1059

Inhibitory Effects of Retinoic Acid Receptor Alpha Stimulants on Murine Cataractogenesis through Suppression of Deregulated Calpains Free

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Nami Nishikiori; Makoto Osanai; Hideki Chiba; Takashi Kojima; Hiroshi Ohguro; Norimasa Sawada

Tags: calpain, central nervous system stimulants, retinoic acid receptor, tretinoin

Investigative Ophthalmology & Visual Science May 2007, Vol.48, 2224-2229. doi:https://doi.org/10.1167/iovs.06-1222

Physiology and Pharmacology

Pharmacokinetics of Intraocular Drug Delivery by Periocular Injections Using Ocular Fluorophotometry Free

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Deepta Ghate; William Brooks; Bernard E. McCarey; Henry F. Edelhauser

Tags: choroid, drug delivery systems, fluorophotometry, injections, mass or substance concentration per volume

Investigative Ophthalmology & Visual Science May 2007, Vol.48, 2230-2237. doi:https://doi.org/10.1167/iovs.06-0954

Clearance of Intravitreal Voriconazole Free

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Ying-Cheng Shen; Mei-Yen Wang; Chun-Yuan Wang; Tsun-Chung Tsai; Hin-Yeung Tsai; Yi-Fen Lee; Li-Chen Wei

Tags: drug clearance, voriconazole

Investigative Ophthalmology & Visual Science May 2007, Vol.48, 2238-2241. doi:https://doi.org/10.1167/iovs.06-1362

Retina

Cross Talk between c-Met and Epidermal Growth Factor Receptor during Retinal Pigment Epithelial Wound Healing Free

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Ke-Ping Xu; Fu-Shin X. Yu

Tags: epidermal growth factor receptors, met gene, wound healing, heparin-binding egf-like growth factor, pigment

Investigative Ophthalmology & Visual Science May 2007, Vol.48, 2242-2248. doi:https://doi.org/10.1167/iovs.06-0560

Optical Coherence Tomography of the Macula in Congenital Achromatopsia Free

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Balázs Varsányi; Gábor Márk Somfai; Balázs Lesch; Rita Vámos; Ágnes Farkas

Tags: achromatopsia, macula densa, macula lutea, optical coherence tomography

Investigative Ophthalmology & Visual Science May 2007, Vol.48, 2249-2253. doi:https://doi.org/10.1167/iovs.06-1173

Correlation between Focal Macular Electroretinograms and Angiographic Findings after Photodynamic Therapy Free

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Kohei Ishikawa; Mineo Kondo; Yasuki Ito; Masato Kikuchi; Hiroaki Nishihara; Chang-Hua Piao; Tadasu Sugita; Hiroko Terasaki

Tags: angiogram, electroretinography, photochemotherapy, visual acuity

Investigative Ophthalmology & Visual Science May 2007, Vol.48, 2254-2259. doi:https://doi.org/10.1167/iovs.06-1277

Automated Detection and Differentiation of Drusen, Exudates, and Cotton-Wool Spots in Digital Color Fundus Photographs for Diabetic Retinopathy Diagnosis Free

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Meindert Niemeijer; Bram van Ginneken; Stephen R. Russell; Maria S. A. Suttorp-Schulten; Michael D. Abràmoff

Tags: color, cotton wool spots, diabetic retinopathy, drusen, exudates

Investigative Ophthalmology & Visual Science May 2007, Vol.48, 2260-2267. doi:https://doi.org/10.1167/iovs.06-0996

Reduced Photoreceptor Damage after Photodynamic Therapy through Blockade of Nitric Oxide Synthase in a Model of Choroidal Neovascularization Free

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Haicheng She; Toru Nakazawa; Akihisa Matsubara; Toshio Hisatomi; Tara A. Young; Norman Michaud; Edward Connolly; Ali Hafezi-Moghadam; Evangelos S. Gragoudas; Joan W. Miller

Tags: choroidal neovascularization, nitric oxide synthase, photoreceptors, rats, photochemotherapy

Investigative Ophthalmology & Visual Science May 2007, Vol.48, 2268-2277. doi:https://doi.org/10.1167/iovs.06-0979

IDOCS: Intelligent Distributed Ontology Consensus System—The Use of Machine Learning in Retinal Drusen Phenotyping Free

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George Thomas; Michael A. Grassi; John R. Lee; Albert O. Edwards; Michael B. Gorin; Ronald Klein; Thomas L. Casavant; Todd E. Scheetz; Edwin M. Stone; Andrew B. Williams

Tags: consensus, drusen, learning, phenotype determination, retinal drusen

Investigative Ophthalmology & Visual Science May 2007, Vol.48, 2278-2284. doi:https://doi.org/10.1167/iovs.06-1022

Retinal Abnormalities in Early Alzheimer’s Disease Free

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Fatmire Berisha; Gilbert T. Feke; Clement L. Trempe; J. Wallace McMeel; Charles L. Schepens

Tags: alzheimer's disease, vascular flow, retinal nerve fiber layer, retina

Investigative Ophthalmology & Visual Science May 2007, Vol.48, 2285-2289. doi:https://doi.org/10.1167/iovs.06-1029

Intraretinal Oxygen Distribution and Consumption during Retinal Artery Occlusion and Graded Hyperoxic Ventilation in the Rat Free

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Dao-Yi Yu; Stephen J. Cringle; Paula K. Yu; Er-Ning Su

Tags: oxygen, respiration, retinal artery occlusion, retina, oxygen consumption

Investigative Ophthalmology & Visual Science May 2007, Vol.48, 2290-2296. doi:https://doi.org/10.1167/iovs.06-1197

High-Resolution In Vivo Imaging of the RPE Mosaic in Eyes with Retinal Disease Free

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Austin Roorda; Yuhua Zhang; Jacque L. Duncan

Tags: diagnostic imaging, eye, mosaicism, retinal diseases, retinal pigment cell

Investigative Ophthalmology & Visual Science May 2007, Vol.48, 2297-2303. doi:https://doi.org/10.1167/iovs.06-1450

Retinal Cell Biology

Neuron Stress and Loss Following Rodent Anterior Ischemic Optic Neuropathy in Double-Reporter Transgenic Mice Free

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Steven L. Bernstein; Yan Guo; Bernard J. Slater; Adam Puche; Shalom E. Kelman

Tags: animals, transgenic, anterior ischemic optic neuropathy, axon, mice, transgenic, neurons

Investigative Ophthalmology & Visual Science May 2007, Vol.48, 2304-2310. doi:https://doi.org/10.1167/iovs.06-0486

Neuroprotection in the Juvenile Rat Model of Light-Induced Retinopathy: Evidence Suggesting a Role for FGF-2 and CNTF Free

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Sandrine Joly; Vincent Pernet; Sylvain Chemtob; Adriana Di Polo; Pierre Lachapelle

Tags: child, ciliary neurotrophic factor, fibroblast growth factor 2, neuroprotection, retina

Investigative Ophthalmology & Visual Science May 2007, Vol.48, 2311-2320. doi:https://doi.org/10.1167/iovs.06-1205

Suppression of Choroidal Neovascularization by Inhibiting Angiotensin-Converting Enzyme: Minimal Role of Bradykinin Free

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Norihiro Nagai; Yuichi Oike; Kanako Izumi-Nagai; Takashi Koto; Shingo Satofuka; Hajime Shinoda; Kousuke Noda; Yoko Ozawa; Makoto Inoue; Kazuo Tsubota; Susumu Ishida

Tags: choroidal neovascularization, angiotensin-converting enzyme, bradykinin, vascular endothelial growth factor a, intercellular adhesion molecule 1

Investigative Ophthalmology & Visual Science May 2007, Vol.48, 2321-2326. doi:https://doi.org/10.1167/iovs.06-1296

Calcitriol Is a Potent Inhibitor of Retinal Neovascularization Free

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Daniel M. Albert; Elizabeth A. Scheef; Shoujian Wang; Farideh Mehraein; Soesiawati R. Darjatmoko; Christine M. Sorenson; Nader Sheibani

Tags: calcitriol, retinal neovascularization

Investigative Ophthalmology & Visual Science May 2007, Vol.48, 2327-2334. doi:https://doi.org/10.1167/iovs.06-1210

A Potential Role for PDGF-C in Experimental and Clinical Proliferative Vitreoretinopathy Free

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Hetian Lei; Peter Hovland; Gisela Velez; Aaron Haran; Debra Gilbertson; Tatsuo Hirose; Andrius Kazlauskas

Tags: platelet-derived growth factor, vitreous body

Investigative Ophthalmology & Visual Science May 2007, Vol.48, 2335-2342. doi:https://doi.org/10.1167/iovs.06-0965

Bilberry (Vaccinium myrtillus) Anthocyanins Modulate Heme Oxygenase-1 and Glutathione S-Transferase-pi Expression in ARPE-19 Cells Free

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Paul E. Milbury; Brigitte Graf; Joanne M. Curran-Celentano; Jeffrey B. Blumberg

Tags: anthocyanins, glutathione, heme, oxygenases, transferase

Investigative Ophthalmology & Visual Science May 2007, Vol.48, 2343-2349. doi:https://doi.org/10.1167/iovs.06-0452

Loss of Insulin-Mediated Vasoprotection: Early Effect of Diabetes on Pericyte-Containing Microvessels of the Retina Free

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Takatoshi Kobayashi; Donald G. Puro

Tags: diabetes mellitus, diabetes mellitus, type 2, insulin, ischemia, microvessels

Investigative Ophthalmology & Visual Science May 2007, Vol.48, 2350-2355. doi:https://doi.org/10.1167/iovs.06-1357

Visual Neuroscience

Neuroprotective Effect of Transcorneal Electrical Stimulation on the Acute Phase of Optic Nerve Injury Free

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Ken-ichiro Miyake; Miho Yoshida; Yoshitsugu Inoue; Yoshio Hata

Tags: electric stimulation, evoked potentials, visual, neuroprotective effect, optic nerve, optic nerve injuries

Investigative Ophthalmology & Visual Science May 2007, Vol.48, 2356-2361. doi:https://doi.org/10.1167/iovs.06-1329

Visual Psychophysics and Physiological Optics

Male Prevalence of Acquired Color Vision Defects in Asymptomatic Carriers of Leber’s Hereditary Optic Neuropathy Free

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Dora Fix Ventura; Mirella Gualtieri; André G. F. Oliveira; Marcelo F. Costa; Peter Quiros; Federico Sadun; Anna Maria de Negri; Solange R. Salomão; Adriana Berezovsky; Jerome Sherman; Alfredo A. Sadun; Valerio Carelli

Tags: carrier state, optic atrophy, hereditary, leber, color vision defect, prevalence

Investigative Ophthalmology & Visual Science May 2007, Vol.48, 2362-2370. doi:https://doi.org/10.1167/iovs.06-0331

The Effect of Myopia on Contrast Thresholds Free

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Bistra D. Stoimenova

Tags: myopia, luminance, refractive errors

Investigative Ophthalmology & Visual Science May 2007, Vol.48, 2371-2374. doi:https://doi.org/10.1167/iovs.05-1377

Pupil Size and Retinal Straylight in the Normal Eye Free

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Luuk Franssen; Juan Tabernero; Joris E. Coppens; Thomas J. T. P. van den Berg

Tags: eye, pupil, pupil size, miosis disorder, diameter

Investigative Ophthalmology & Visual Science May 2007, Vol.48, 2375-2382. doi:https://doi.org/10.1167/iovs.06-0759

Legibility Variations of Chinese Characters and Implications for Visual Acuity Measurement in Chinese Reading Population Free

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Jun-Yun Zhang; Ting Zhang; Feng Xue; Lei Liu; Cong Yu

Tags: chinese (other dialects), chinese people, personality character, visual acuity, reading (activity)

Investigative Ophthalmology & Visual Science May 2007, Vol.48, 2383-2390. doi:https://doi.org/10.1167/iovs.06-1195

Erratum

ERRATUM Free

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