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Anatomy and Pathology/Oncology

Multiplex Ligation-Dependent Probe Amplification of Uveal Melanoma: Correlation with Metastatic Death Free
PDF
Bertil Damato; Justyna Dopierala; Annelies Klaasen; Marcory van Dijk; Julie Sibbring; Sarah E. Coupland
Tags: amplification, ligation, uveal melanoma, neoplasms, dna
Investigative Ophthalmology & Visual Science July 2009, Vol.50, 3048-3055. doi:https://doi.org/10.1167/iovs.08-3165
A Targeted Inhibitor of the Alternative Complement Pathway Reduces Angiogenesis in a Mouse Model of Age-Related Macular Degeneration Free
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Bärbel Rohrer; Qin Long; Beth Coughlin; R. Brooks Wilson; Yuxiang Huang; Fei Qiao; Peter H. Tang; Kannan Kunchithapautham; Gary S. Gilkeson; Stephen Tomlinson
Tags: age-related macular degeneration, angiogenesis, choroidal neovascularization, complement pathway, alternative, familial hypercholesterolemia
Investigative Ophthalmology & Visual Science July 2009, Vol.50, 3056-3064. doi:https://doi.org/10.1167/iovs.08-2222

Biochemistry and Molecular Biology

Revisiting Old Drugs as Novel Agents for Retinoblastoma: In Vitro and In Vivo Antitumor Activity of Cardenolides Free
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Christophe Antczak; Carolyn Kloepping; Constantin Radu; Thorsten Genski; Lutz Müller-Kuhrt; Karsten Siems; Elisa de Stanchina; David H. Abramson; Hakim Djaballah
Tags: cardenolides, ouabain, retinoblastoma, screening
Investigative Ophthalmology & Visual Science July 2009, Vol.50, 3065-3073. doi:https://doi.org/10.1167/iovs.08-3158
Early Synaptic Defects in tulp1 −/− Mice Free
PDF
Gregory H. Grossman; Gayle J. T. Pauer; Umadevi Narendra; Neal S. Peachey; Stephanie A. Hagstrom
Tags: mice, photoreceptors, synapses, dendrites, retina
Investigative Ophthalmology & Visual Science July 2009, Vol.50, 3074-3083. doi:https://doi.org/10.1167/iovs.08-3190
Localization of Age-Related Macular Degeneration-Associated ARMS2 in Cytosol, Not Mitochondria Free
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Gaofeng Wang; Kylee L. Spencer; Brenda L. Court; Lana M. Olson; William K. Scott; Jonathan L. Haines; Margaret A. Pericak-Vance
Tags: cytosol, mitochondria, tissue degeneration, single nucleotide polymorphism, htra1 gene
Investigative Ophthalmology & Visual Science July 2009, Vol.50, 3084-3090. doi:https://doi.org/10.1167/iovs.08-3240
Imatinib Mesylate and AMN107 Inhibit PDGF-Signaling in Orbital Fibroblasts: A Potential Treatment for Graves’ Ophthalmopathy Free
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Leendert van Steensel; Dion Paridaens; Benjamin Schrijver; Gemma M. Dingjan; Paul L. A. van Daele; P. Martin van Hagen; Willem A. van den Bosch; Hemmo A. Drexhage; Herbert Hooijkaas; Willem A. Dik
Tags: fibroblasts, imatinib mesylate, nilotinib, platelet-derived growth factor, graves' ophthalmopathy
Investigative Ophthalmology & Visual Science July 2009, Vol.50, 3091-3098. doi:https://doi.org/10.1167/iovs.08-2443
Expression of Cytochrome P450 (CYP) Enzymes in Human Nonpigmented Ciliary Epithelial Cells: Induction of CYP1B1 Expression by TCDD Free
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Marjo Volotinen; Jukka Mäenpää; Esko Kankuri; Olli Oksala; Olavi Pelkonen; Miki Nakajima; Tsuyoshi Yokoi; Jukka Hakkola
Tags: cytochrome p450, enzymes, epithelial cells, rna, messenger, tetrachlorodibenzodioxin
Investigative Ophthalmology & Visual Science July 2009, Vol.50, 3099-3105. doi:https://doi.org/10.1167/iovs.08-2790
Potential for Transcriptional Upregulation of Cochlin in Glaucomatous Trabecular Meshwork: A Combinatorial Bioinformatic and Biochemical Analytical Approach Free
PDF
Renata G. Picciani; Anthony Diaz; Richard K. Lee; Sanjoy K. Bhattacharya
Tags: glaucoma, proteins, trabecular meshwork, transcription, genetic, up-regulation (physiology)
Investigative Ophthalmology & Visual Science July 2009, Vol.50, 3106-3111. doi:https://doi.org/10.1167/iovs.08-3106

Clinical and Epidemiologic Research

Quality of Life in Patients with Leber Hereditary Optic Neuropathy Free
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Matthew Anthony Kirkman; Alex Korsten; Miriam Leonhardt; Konstantin Dimitriadis; Ireneaus F. De Coo; Thomas Klopstock; Philip G. Griffiths; Gavin Hudson; Patrick F. Chinnery; Patrick Yu-Wai-Man
Tags: optic atrophy, hereditary, leber, quality of life, visual impairment
Investigative Ophthalmology & Visual Science July 2009, Vol.50, 3112-3115. doi:https://doi.org/10.1167/iovs.08-3166
An International Collaborative Family-Based Whole-Genome Linkage Scan for High-Grade Myopia Free
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Yi-Ju Li; Jeremy A. Guggenheim; Anuradha Bulusu; Ravikanth Metlapally; Diana Abbott; Francois Malecaze; Patrick Calvas; Thomas Rosenberg; Sandrine Paget; Rosalind C. Creer; George Kirov; Michael J. Owen; Bei Zhao; Tristan White; David A. Mackey; Terri L. Young
Tags: family, genome, myopia, phenotype, single nucleotide polymorphism
Investigative Ophthalmology & Visual Science July 2009, Vol.50, 3116-3127. doi:https://doi.org/10.1167/iovs.08-2781

Cornea

The Effect of Growth Factor Signaling on Keratocytes In Vitro and Its Relationship to the Phases of Stromal Wound Repair Free
PDF
LaTia Etheredge; Bradley P. Kane; John R. Hassell
Tags: fibroblast growth factor 2, growth factor, insulin-like growth factor i, keratocytes, platelet-derived growth factor
Investigative Ophthalmology & Visual Science July 2009, Vol.50, 3128-3136. doi:https://doi.org/10.1167/iovs.08-3077
Depletion of Passenger Leukocytes from Corneal Grafts: An Effective Means of Promoting Transplant Survival? Free
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Xian Zhang; Linling Shen; Yiping Jin; Daniel R. Saban; Sunil K. Chauhan; Reza Dana
Tags: cd45 antigens, cornea, keratoplasty, leukocytes, transplantation
Investigative Ophthalmology & Visual Science July 2009, Vol.50, 3137-3144. doi:https://doi.org/10.1167/iovs.08-1899
Detection of Subepithelial Fibrosis Associated with Corneal Stromal Edema by Second Harmonic Generation Imaging Microscopy Free
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Naoyuki Morishige; Naoyuki Yamada; Shinichiro Teranishi; Tai-ichiro Chikama; Teruo Nishida; Atsushi Takahara
Tags: cornea, diagnostic imaging, edema, fibrosis, harmonics
Investigative Ophthalmology & Visual Science July 2009, Vol.50, 3145-3150. doi:https://doi.org/10.1167/iovs.08-3309
Immunologic Mechanisms of Corneal Allografts Reconstituted from Cultured Allogeneic Endothelial Cells in an Immune-Privileged Site Free
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Takahiko Hayashi; Satoru Yamagami; Kazumi Tanaka; Seiichi Yokoo; Tomohiko Usui; Shiro Amano; Nobuhisa Mizuki
Tags: allografting, chronic exertional compartment syndrome, cornea, immunology, keratoplasty
Investigative Ophthalmology & Visual Science July 2009, Vol.50, 3151-3158. doi:https://doi.org/10.1167/iovs.08-2530
Lower Volumes of Tear Menisci in Contact Lens Wearers with Dry Eye Symptoms Free
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Qi Chen; Jianhua Wang; Meixiao Shen; Chunyan Cai; Jianhua Li; Lele Cui; Jia Qu; Fan Lu
Tags: contact lenses, dry eye syndromes, knee meniscus, lens (device), lens, crystalline
Investigative Ophthalmology & Visual Science July 2009, Vol.50, 3159-3163. doi:https://doi.org/10.1167/iovs.08-2794
Cytopathology and Exocrine Dysfunction Induced in Ex Vivo Rabbit Lacrimal Gland Acinar Cell Models by Chronic Exposure to Histamine or Serotonin Free
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Michelle L. McDonald; Yanru Wang; Shivaram Selvam; Tamako Nakamura; Robert H. Chow; Joel E. Schechter; Samuel C. Yiu; Austin K. Mircheff
Tags: acinar cells, beta-n-acetylhexosaminidase, bodily secretions, hexosaminidases, histamine
Investigative Ophthalmology & Visual Science July 2009, Vol.50, 3164-3175. doi:https://doi.org/10.1167/iovs.08-2768
Concentration and Bioavailability of Ciprofloxacin and Teicoplanin in the Cornea Free
PDF
Stephen B. Kaye; Timothy Neal; Steven Nicholson; Jagoda Szkurlat; Sharon Bamber; Andrew C. Baddon; Sarah Anderson; Keeley Seddon; Nichola Dwyer; Andrew M. Lovering; Godfrey Smith
Tags: antimicrobials, ciprofloxacin, cornea, mass or substance concentration per volume, teicoplanin
Investigative Ophthalmology & Visual Science July 2009, Vol.50, 3176-3184. doi:https://doi.org/10.1167/iovs.08-3201
CRB1 Gene Mutations Are Associated with Keratoconus in Patients with Leber Congenital Amaurosis Free
PDF
Timothy T. McMahon; Linda S. Kim; Gerald A. Fishman; Edwin M. Stone; Xinping C. Zhao; Richard W. Yee; Jarema Malicki
Tags: keratoconus, leber's amaurosis, mutation
Investigative Ophthalmology & Visual Science July 2009, Vol.50, 3185-3187. doi:https://doi.org/10.1167/iovs.08-2886
Amniotic Membrane Transplantation Induces Apoptosis in T Lymphocytes in Murine Corneas with Experimental Herpetic Stromal Keratitis Free
PDF
Dirk Bauer; Susanne Wasmuth; Maren Hennig; Hanna Baehler; Klaus-Peter Steuhl; Arnd Heiligenhaus
Tags: apoptosis, cornea, cytokine, stromal keratitis, t-lymphocytes
Investigative Ophthalmology & Visual Science July 2009, Vol.50, 3188-3198. doi:https://doi.org/10.1167/iovs.08-3041
Biomechanical Properties of the Cornea in Fuchs’ Corneal Dystrophy Free
PDF
María A. del Buey; José A. Cristóbal; Francisco J. Ascaso; Laura Lavilla; Elena Lanchares
Tags: cornea, hereditary corneal dystrophy, eye, intraocular pressure
Investigative Ophthalmology & Visual Science July 2009, Vol.50, 3199-3202. doi:https://doi.org/10.1167/iovs.08-3312
Production and Activity of Matrix Metalloproteinase-9 on the Ocular Surface Increase in Dysfunctional Tear Syndrome Free
PDF
Suksri Chotikavanich; Cintia S. de Paiva; De Quan Li; Joseph J. Chen; Fang Bian; William J. Farley; Stephen C. Pflugfelder
Tags: gelatinase b, syndrome
Investigative Ophthalmology & Visual Science July 2009, Vol.50, 3203-3209. doi:https://doi.org/10.1167/iovs.08-2476

Eye Movements, Strabismus, Amblyopia and Neuro-ophthalmology

Replication of the Recessive STBMS1 Locus but with Dominant Inheritance Free
PDF
Aine Rice; Jérémie Nsengimana; Ian G. Simmons; Carmel Toomes; Janice Hoole; Colin E. Willoughby; Frances Cassidy; Grange A. Williams; Nick D. George; Eamonn Sheridan; Terri L. Young; Tim I. Hunter; Brendan T. Barrett; David B. Elliott; D. Tim Bishop; Chris F. Inglehearn
Tags: dominant inheritance, esotropia, family, strabismus, genetic pedigree
Investigative Ophthalmology & Visual Science July 2009, Vol.50, 3210-3217. doi:https://doi.org/10.1167/iovs.07-1631
Disrupted Retinotopic Maps in Amblyopia Free
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Behzad Mansouri; Bruce C. Hansen; Robert F. Hess
Tags: amblyopia, maps
Investigative Ophthalmology & Visual Science July 2009, Vol.50, 3218-3225. doi:https://doi.org/10.1167/iovs.08-2914
Immunolocalization of GQ1b and Related Gangliosides in Human Extraocular Neuromuscular Junctions and Muscle Spindles Free
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Jing-Xia Liu; Hugh J. Willison; Fatima Pedrosa-Domellöf
Tags: gangliosides, muscle spindles, muscle, neuromuscular junction, epitopes
Investigative Ophthalmology & Visual Science July 2009, Vol.50, 3226-3232. doi:https://doi.org/10.1167/iovs.08-3333

Glaucoma

Postoperative Use of Bevacizumab as an Antifibrotic Agent in Glaucoma Filtration Surgery in the Rabbit Free
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Farnaz Memarzadeh; Rohit Varma; Le-Tien Lin; Jignesh G. Parikh; Laurie Dustin; Ana Alcaraz; Dean Eliott
Tags: bevacizumab, blister, filtering surgery, glaucoma, oryctolagus cuniculus
Investigative Ophthalmology & Visual Science July 2009, Vol.50, 3233-3237. doi:https://doi.org/10.1167/iovs.08-2441
Expression of Prostaglandin PGE2 Receptors under Conditions of Aging and Stress and the Protective Effect of the EP2 Agonist Butaprost on Retinal Ischemia Free
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Neville N. Osborne; Guang-Yu Li; Dan Ji; Belmira L. Andrade da Costa; Rebecca J. Fawcett; Kui Dong Kang; Kay D. Rittenhouse
Tags: aging, agonists, ischemia, physiologic reperfusion, prostaglandins e
Investigative Ophthalmology & Visual Science July 2009, Vol.50, 3238-3248. doi:https://doi.org/10.1167/iovs.08-3185
Combining Ganglion Cell Topology and Data of Patients with Glaucoma to Determine a Structure–Function Map Free
PDF
Andrew Turpin; Geoff P. Sampson; Allison M. McKendrick
Tags: anatomy, regional, axon, eye, ganglia, glaucoma
Investigative Ophthalmology & Visual Science July 2009, Vol.50, 3249-3256. doi:https://doi.org/10.1167/iovs.08-2492

Immunology and Microbiology

Genetic Dissociation of Dacryoadenitis and Sialadenitis in a Sjögren’s Syndrome Mouse Model with Common and Different Susceptibility Gene Loci Free
PDF
Tomoyuki Kamao; Tatsuhiko Miyazaki; Yoshiko Soga; Hiroaki Komori; Miho Terada; Yuichi Ohashi; Masato Nose
Tags: dacryoadenitis, disease susceptibility, mice, sialadenitis, sjogren's syndrome
Investigative Ophthalmology & Visual Science July 2009, Vol.50, 3257-3265. doi:https://doi.org/10.1167/iovs.08-3132
Protective Role of γδ T Cells in Spontaneous Ocular Inflammation Free
PDF
Rebecca L. O'Brien; Molly A. Taylor; Jacqueline Hartley; Tanja Nuhsbaum; Steve Dugan; Kevin Lahmers; M. Kemal Aydintug; J. M. Wands; Christina L. Roark; Willi K. Born
Tags: eye inflammation, keratitis, mice, t-lymphocytes, autoimmune diseases
Investigative Ophthalmology & Visual Science July 2009, Vol.50, 3266-3274. doi:https://doi.org/10.1167/iovs.08-2982
Optic Neuritis in Different Strains of Mice by a Recombinant HSV-1 Expressing Murine Interleukin-2 Free
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Mandana Zandian; Raelene Belisle; Kevin R. Mott; Steven Nusinowitz; Florence M. Hofman; Homayon Ghiasi
Tags: aldesleukin, demyelination, human herpesvirus 1, mice, optic nerve
Investigative Ophthalmology & Visual Science July 2009, Vol.50, 3275-3282. doi:https://doi.org/10.1167/iovs.08-3211

Lens

αB-crystallin: A Golgi-Associated Membrane Protein in the Developing Ocular Lens Free
PDF
Rajendra K. Gangalum; Suraj P. Bhat
Tags: crystallins, golgi apparatus, lens, crystalline, membrane proteins, lens (device)
Investigative Ophthalmology & Visual Science July 2009, Vol.50, 3283-3290. doi:https://doi.org/10.1167/iovs.08-3052
Comprehensive Mutational Screening in a Cohort of Danish Families with Hereditary Congenital Cataract Free
PDF
Lars Hansen; Annemette Mikkelsen; Peter Nürnberg; Gudrun Nürnberg; Iram Anjum; Hans Eiberg; Thomas Rosenberg
Tags: cataract, cohort studies, congenital cataract, danish, family
Investigative Ophthalmology & Visual Science July 2009, Vol.50, 3291-3303. doi:https://doi.org/10.1167/iovs.08-3149
Ovarian Hormone Modulation of Radiation-Induced Cataractogenesis: Dose-Response Studies Free
PDF
Robert M. Bigsby; Shailaja Valluri; Jennifer Lopez; Marc S. Mendonca; Andrea Caperell-Grant; Colleen DesRosiers; Joseph R. Dynlacht
Tags: cataract, ovarian hormone, radiation, estradiol, estrogen
Investigative Ophthalmology & Visual Science July 2009, Vol.50, 3304-3310. doi:https://doi.org/10.1167/iovs.08-3262
Tryptophan Metabolites from Young Human Lenses and the Photooxidation of Ascorbic Acid by UVA Light Free
PDF
Beryl J. Ortwerth; Jaya Bhattacharyya; Ekaterina Shipova
Tags: ascorbic acid, lens, crystalline, oxidation, ultraviolet a radiation, tryptophan
Investigative Ophthalmology & Visual Science July 2009, Vol.50, 3311-3319. doi:https://doi.org/10.1167/iovs.08-2927

Physiology and Pharmacology

Prostanoid EP4 Receptor Stimulation Produces Ocular Hypotension by a Mechanism That Does Not Appear to Involve Uveoscleral Outflow Free
PDF
David F. Woodward; Siv F. E. Nilsson; Carol B. Toris; Alexander B. Kharlamb; Amelia L. Nieves; Achim H.-P. Krauss
Tags: alprostadil, eye, intraocular pressure, ocular hypotension, prostaglandins
Investigative Ophthalmology & Visual Science July 2009, Vol.50, 3320-3328. doi:https://doi.org/10.1167/iovs.08-3031
Functional and Molecular Characterization of the Endothelin System in Retinal Arterioles Free
PDF
Travis W. Hein; Yi Ren; Zhaoxu Yuan; Wenjuan Xu; Sonal Somvanshi; Taiji Nagaoka; Akitoshi Yoshida; Lih Kuo
Tags: arteriole, endothelin-1, endothelins
Investigative Ophthalmology & Visual Science July 2009, Vol.50, 3329-3336. doi:https://doi.org/10.1167/iovs.08-3129
NC-1059: A Channel-Forming Peptide That Modulates Drug Delivery across In Vitro Corneal Epithelium Free
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Jesica Martin; Pradeep Malreddy; Takeo Iwamoto; Lisa C. Freeman; Harriet J. Davidson; John M. Tomich; Bruce D. Schultz
Tags: corneal epithelium, dextran, drug delivery systems, epithelium, fluorescein-5-isothiocyanate
Investigative Ophthalmology & Visual Science July 2009, Vol.50, 3337-3345. doi:https://doi.org/10.1167/iovs.08-3053
A Drug-Eluting Contact Lens Free
PDF
Joseph B. Ciolino; Todd R. Hoare; Naomi G. Iwata; Irmgard Behlau; Claes H. Dohlman; Robert Langer; Daniel S. Kohane
Tags: ciprofloxacin, contact lenses, fluorescein, polyhydroxyethyl methacrylate, drug release
Investigative Ophthalmology & Visual Science July 2009, Vol.50, 3346-3352. doi:https://doi.org/10.1167/iovs.08-2826
Human Trabecular Meshwork Cell Volume Decrease by NO-Independent Soluble Guanylate Cyclase Activators YC-1 and BAY-58-2667 Involves the BKCa Ion Channel Free
PDF
William M. Dismuke; Najam A. Sharif; Dorette Z. Ellis
Tags: cell volume, cyclic gmp, ion channels, soluble guanylyl cyclase, transcriptional activation
Investigative Ophthalmology & Visual Science July 2009, Vol.50, 3353-3359. doi:https://doi.org/10.1167/iovs.08-3127

Retina

The Role of Supplemental Oxygen and JAK/STAT Signaling in Intravitreous Neovascularization in a ROP Rat Model Free
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Grace Byfield; Steve Budd; M. Elizabeth Hartnett
Tags: oxygen, signal transduction, stat family gene, statim, vitreous neovascularization
Investigative Ophthalmology & Visual Science July 2009, Vol.50, 3360-3365. doi:https://doi.org/10.1167/iovs.08-3256
Quantitative Subanalysis of Cystoid Spaces and Outer Nuclear Layer Using Optical Coherence Tomography in Age-Related Macular Degeneration Free
PDF
Amir H. Kashani; Pearse A. Keane; Laurie Dustin; Alexander C. Walsh; Srinivas R. Sadda
Tags: age-related macular degeneration, exudative age-related macular degeneration, optical coherence tomography, retina, software
Investigative Ophthalmology & Visual Science July 2009, Vol.50, 3366-3373. doi:https://doi.org/10.1167/iovs.08-2691
Interocular Difference and Duration for Doubling of the Minimal Angle of Visual Resolution in Patients with Stargardt Disease Free
PDF
Manal Hajali; Gerald A. Fishman; Robert J. Anderson; J. Jason McAnany
Tags: stargardt's disease, eye
Investigative Ophthalmology & Visual Science July 2009, Vol.50, 3374-3377. doi:https://doi.org/10.1167/iovs.08-2775
Evaluation of Optical Coherence Tomography Retinal Thickness Parameters for Use in Clinical Trials for Neovascular Age-Related Macular Degeneration Free
PDF
Pearse A. Keane; Sandra Liakopoulos; Renu V. Jivrajka; Karen T. Chang; Tarek Alasil; Alexander C. Walsh; Srinivas R. Sadda
Tags: exudative age-related macular degeneration, optical coherence tomography, software
Investigative Ophthalmology & Visual Science July 2009, Vol.50, 3378-3385. doi:https://doi.org/10.1167/iovs.08-2728
Complement Component 3 (C3) Haplotypes and Risk of Advanced Age-Related Macular Degeneration Free
PDF
Kyu Hyung Park; Brooke L. Fridley; Euijung Ryu; Nirubol Tosakulwong; Albert O. Edwards
Tags: age-related macular degeneration, complement 3, haplotypes, single nucleotide polymorphism, alleles
Investigative Ophthalmology & Visual Science July 2009, Vol.50, 3386-3393. doi:https://doi.org/10.1167/iovs.08-3231
Growth Factors Outside the PDGF Family Drive Experimental PVR Free
PDF
Hetian Lei; Gisela Velez; Peter Hovland; Tatsuo Hirose; Debra Gilbertson; Andrius Kazlauskas
Tags: growth factor, platelet-derived growth factor, family, vitreous body, oryctolagus cuniculus
Investigative Ophthalmology & Visual Science July 2009, Vol.50, 3394-3403. doi:https://doi.org/10.1167/iovs.08-3042
Selective Loss of Inner Retinal Layer Thickness in Type 1 Diabetic Patients with Minimal Diabetic Retinopathy Free
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Hille W. van Dijk; Pauline H. B. Kok; Mona Garvin; Milan Sonka; J. Hans DeVries; Robert P. J. Michels; Mirjam E. J. van Velthoven; Reinier O. Schlingemann; Frank D. Verbraak; Michael D. Abràmoff
Tags: diabetes mellitus, diabetic retinopathy, diabetes mellitus, type 1
Investigative Ophthalmology & Visual Science July 2009, Vol.50, 3404-3409. doi:https://doi.org/10.1167/iovs.08-3143
Effects of Dioxin on Vascular Endothelial Growth Factor (VEGF) Production in the Retina Associated with Choroidal Neovascularization Free
PDF
Aya Takeuchi; Masaru Takeuchi; Kosuke Oikawa; Koh-hei Sonoda; Yoshihiko Usui; Yoko Okunuki; Atsunobu Takeda; Yuji Oshima; Keiichi Yoshida; Masahiko Usui; Hiroshi Goto; Masahiko Kuroda
Tags: choroidal neovascularization, mice, retina, rna, messenger, tetrachlorodibenzodioxin
Investigative Ophthalmology & Visual Science July 2009, Vol.50, 3410-3416. doi:https://doi.org/10.1167/iovs.08-2299
Identification of Optical Density Ratios in Subretinal Fluid as a Clinically Relevant Biomarker in Exudative Macular Disease Free
PDF
Christian Ahlers; Isabelle Golbaz; Elisa Einwallner; Roman Dunavölgyi; Panagiotis Malamos; Geraldine Stock; Christian Pruente; Ursula Schmidt-Erfurth
Tags: age-related macular degeneration, biological markers, follow-up, macular disorders, optics
Investigative Ophthalmology & Visual Science July 2009, Vol.50, 3417-3424. doi:https://doi.org/10.1167/iovs.08-2759
Subretinal Transplantation of Forebrain Progenitor Cells in Nonhuman Primates: Survival and Intact Retinal Function Free
PDF
Peter J. Francis; Shaomei Wang; Yi Zhang; Anna Brown; Thomas Hwang; Trevor J. McFarland; Brett G. Jeffrey; Bin Lu; Lynda Wright; Binoy Appukuttan; David J. Wilson; J. Timothy Stout; Martha Neuringer; David M. Gamm; Raymond D. Lund
Tags: eye, primates, prosencephalon, stem cells, transplantation
Investigative Ophthalmology & Visual Science July 2009, Vol.50, 3425-3431. doi:https://doi.org/10.1167/iovs.08-2908
Macular Thickness Measurements in Healthy Eyes Using Six Different Optical Coherence Tomography Instruments Free
PDF
Ute E. K. Wolf-Schnurrbusch; Lala Ceklic; Christian K. Brinkmann; Milko E. Iliev; Manuel Frey; Simon P. Rothenbuehler; Volker Enzmann; Sebastian Wolf
Tags: eye, optical coherence tomography, copernicus trial
Investigative Ophthalmology & Visual Science July 2009, Vol.50, 3432-3437. doi:https://doi.org/10.1167/iovs.08-2970
Comparative Evaluation of Apoptotic Activity in Photoreceptor Cells after Intravitreal Injection of Bevacizumab and Pegaptanib Sodium in Rabbits Free
PDF
Berrin Avci; Remzi Avci; Ümit Übeyt Inan; Berkant Kaderli
Tags: bevacizumab, intravitreal injections, oryctolagus cuniculus, pegaptanib, photoreceptors
Investigative Ophthalmology & Visual Science July 2009, Vol.50, 3438-3446. doi:https://doi.org/10.1167/iovs.08-2871
Cysteine-rich 61, a Member of the CCN Family, as a Factor Involved in the Pathogenesis of Proliferative Diabetic Retinopathy Free
PDF
Jian-Jang You; Chang-Hao Yang; Muh-Shy Chen; Chung-May Yang
Tags: antibodies, chemotaxis, complex communication needs, cysteine, endothelial cells
Investigative Ophthalmology & Visual Science July 2009, Vol.50, 3447-3455. doi:https://doi.org/10.1167/iovs.08-2603
A Novel Rat Model with Obesity-Associated Retinal Degeneration Free
PDF
Geereddy Bhanuprakash Reddy; Vidyullatha Vasireddy; Md Nawajes A. Mandal; Mrudula Tiruvalluru; Xiaofei F. Wang; Monica M. Jablonski; Giridharan Nappanveettil; Radha Ayyagari
Tags: obesity, retina, retinal degeneration, rats
Investigative Ophthalmology & Visual Science July 2009, Vol.50, 3456-3463. doi:https://doi.org/10.1167/iovs.08-2498
Test–Retest Variability of Microperimetry Using the Nidek MP1 in Patients with Macular Disease Free
PDF
Fred K. Chen; Praveen J. Patel; Wen Xing; Catey Bunce; Catherine Egan; Adnan T. Tufail; Peter J. Coffey; Gary S. Rubin; Lyndon Da Cruz
Tags: age-related macular degeneration, macular disorders, scotoma, mountain sickness, chronic, eye
Investigative Ophthalmology & Visual Science July 2009, Vol.50, 3464-3472. doi:https://doi.org/10.1167/iovs.08-2926

Retinal Cell Biology

Expression and Modulation of RPE Cell Membrane Complement Regulatory Proteins Free
PDF
Ping Yang; Jillian Tyrrell; Ian Han; Glenn J. Jaffe
Tags: antigens, cd55, antigens, cd59, cd46 antigen, complement system proteins, cytokine
Investigative Ophthalmology & Visual Science July 2009, Vol.50, 3473-3481. doi:https://doi.org/10.1167/iovs.08-3202
Steroids Do Not Prevent Photoreceptor Degeneration in the Light-Exposed T4R Rhodopsin Mutant Dog Retina Irrespective of AP-1 Inhibition Free
PDF
Danian Gu; William A. Beltran; Sue Pearce-Kelling; Zexiao Li; Gregory M. Acland; Gustavo D. Aguirre
Tags: dog, domestic, light exposure, photoreceptors, retina, rhodopsin
Investigative Ophthalmology & Visual Science July 2009, Vol.50, 3482-3494. doi:https://doi.org/10.1167/iovs.08-3111
Regulation of Retinal Photoreceptor Phagocytosis in a Diurnal Mammal by Circadian Clocks and Ambient Lighting Free
PDF
Corina Bobu; David Hicks
Tags: lighting, mammals, phagocytosis, photoreceptors, regulation
Investigative Ophthalmology & Visual Science July 2009, Vol.50, 3495-3502. doi:https://doi.org/10.1167/iovs.08-3145
Maturation of the Fetal Human Choriocapillaris Free
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Takayuki Baba; Rhonda Grebe; Takuya Hasegawa; Imran Bhutto; Carol Merges; D. Scott McLeod; Gerard A. Lutty
Tags: chief complaint, endothelial cells, enzymes, fenestration, fetus
Investigative Ophthalmology & Visual Science July 2009, Vol.50, 3503-3511. doi:https://doi.org/10.1167/iovs.08-2614
Prevention of Ocular Inflammation in Endotoxin-Induced Uveitis with Resveratrol by Inhibiting Oxidative Damage and Nuclear Factor–κB Activation Free
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Shunsuke Kubota; Toshihide Kurihara; Hiroshi Mochimaru; Shingo Satofuka; Kousuke Noda; Yoko Ozawa; Yuichi Oike; Susumu Ishida; Kazuo Tsubota
Tags: resveratrol, eye inflammation, uveitis, endotoxins, prevention
Investigative Ophthalmology & Visual Science July 2009, Vol.50, 3512-3519. doi:https://doi.org/10.1167/iovs.08-2666

Visual Psychophysics and Physiological Optics

Short-Term Adaptive Modification of Dynamic Ocular Accommodation Free
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Shrikant R. Bharadwaj; Indu Vedamurthy; Clifton M. Schor
Tags: velocity, visual accommodation
Investigative Ophthalmology & Visual Science July 2009, Vol.50, 3520-3528. doi:https://doi.org/10.1167/iovs.08-2577
Refractive Shifts in Four Selected Artificial Vitreous Substitutes Based on Gullstrand-Emsley and Liou-Brennan Schematic Eyes Free
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Qianying Gao; Xiang Chen; Jian Ge; Yongji Liu; Zhaoxin Jiang; Zhi Lin; Yaqin Liu
Tags: eye, vitreous substitute, silicone oils, vitreous body, balanced salt solutions
Investigative Ophthalmology & Visual Science July 2009, Vol.50, 3529-3534. doi:https://doi.org/10.1167/iovs.08-2802

Clinical Trials

A Single Intraoperative Sub-Tenon’s Capsule Injection of Triamcinolone and Ciprofloxacin in a Controlled-Release System for Cataract Surgery Free
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Fernando Paganelli; José A. Cardillo; Luiz A. S. Melo, Jr; David R. Lucena; Arnobio A. Silva, Jr; Anselmo G. Oliveira; Ana L. Höfling-Lima; Quan Dong Nguyen; Baruch D. Kuppermann; Rubens Belfort, Jr; and the Brazilian Ocular Pharmacology and Pharmaceutical Technology Research Group (BOPP)
Tags: cataract surgery, ciprofloxacin, episcleral block, intraoperative care, prednisolone
Investigative Ophthalmology & Visual Science July 2009, Vol.50, 3041-3047. doi:https://doi.org/10.1167/iovs.08-2920

Erratum

ERRATUM Free
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Investigative Ophthalmology & Visual Science July 2009, Vol.50, 3136. doi:
Copyright © 2025 Association for Research in Vision and Ophthalmology.
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