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Research Highlight

Pupillometry: A Clinical Measure of Retinal Function in Inherited Disease Free
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Stewart Thompson
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5570. doi:https://doi.org/10.1167/iovs.12-10616
Toward a Better Understanding of Tear Film Stability Free
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Jerry R. Paugh
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5750. doi:https://doi.org/10.1167/iovs.12-10645

Anatomy and Pathology/Oncology

Ocular Anterior Segment Dysgenesis upon Ablation of p120 Catenin in Neural Crest Cells Free
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Huiyu Tian; Ellen Sanders; Albert Reynolds; Frans van Roy; Jolanda van Hengel
Tags: ablation, acute stress disorder, atrial septal defect, autism spectrum disorder, congenital abnormality
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5139-5153. doi:https://doi.org/10.1167/iovs.12-9472
Different Subsets of Tumor-Infiltrating Lymphocytes Correlate with Macrophage Influx and Monosomy 3 in Uveal Melanoma Free
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Inge H. G. Bronkhorst; T. H. Khanh Vu; Ekaterina S. Jordanova; Gregorius P. M. Luyten; Sjoerd H. van der Burg; Martine J. Jager
Tags: lymphocytes, tumor-infiltrating, macrophages, monosomy, neoplasms, uveal melanoma
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5370-5378. doi:https://doi.org/10.1167/iovs.11-9280
Transscleral Optical Spectroscopy of Uveal Melanoma in Enucleated Human Eyes Free
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Jørgen Krohn; Pontus Svenmarker; Can T. Xu; Sverre J. Mørk; Stefan Andersson-Engels
Tags: eye, melanoma, neoplasms, optics, spectrum analysis
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5379-5385. doi:https://doi.org/10.1167/iovs.12-9840
Immune Mediators in Vitreous Fluids from Patients with Vitreoretinal B-Cell Lymphoma Free
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Yoshihiko Usui; Yoshihiro Wakabayashi; Yoko Okunuki; Keisuke Kimura; Kazuki Tajima; Ryusaku Matsuda; Shunichiro Ueda; Juan Ma; Takeshi Nagai; Hideki Mori; Takeshi Kezuka; Toshitaka Nagao; Hiroshi Goto
Tags: b-cell lymphomas, body fluid, immune mediator, vitreous body, biological response modifiers
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5395-5402. doi:https://doi.org/10.1167/iovs.11-8719
Muscarinic Antagonist Control of Myopia: Evidence for M4 and M1 Receptor-Based Pathways in the Inhibition of Experimentally-Induced Axial Myopia in the Tree Shrew Free
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Baskar Arumugam; Neville A. McBrien
Tags: antagonists, myopia, tupaiidae
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5827-5837. doi:https://doi.org/10.1167/iovs.12-9943

Biochemistry and Molecular Biology

Antifibrotic Effects of Quercetin in Primary Orbital Fibroblasts and Orbital Fat Tissue Cultures of Graves' Orbitopathy Free
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Jin Sook Yoon; Min Kyung Chae; Sun Young Jang; Sang Yeul Lee; Eun Jig Lee
Tags: gelatinase a, quercetin, tissue culture, fibroblasts, gelatinase b
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5921-5929. doi:https://doi.org/10.1167/iovs.12-9646
Pretreatment with Proteasome Inhibitors Protects against Oxidative Injuries via PPARα-Dependent and -Independent Pathways in ARPE-19 Cells Free
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Jingjing Cai; Lin Sun; Bing Lin; Meng'ai Wu; Jia Qu; B. Joy Snider; Shengzhou Wu
Tags: proteasome inhibitors, wounds and injuries, multicatalytic endopeptidase complex, mechlorethamine
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5967-5974. doi:https://doi.org/10.1167/iovs.12-10048

Clinical and Epidemiologic Research

Visual Characteristics of Elderly Night Drivers in the Salisbury Eye Evaluation Driving Study Free
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Mona A. Kaleem; Beatriz E. Munoz; Cynthia A. Munro; Emily W. Gower; Sheila K. West
Tags: contrast sensitivity, eye, night time, older adult, visual fields
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5161-5167. doi:https://doi.org/10.1167/iovs.12-9866
Association of Conjunctival Bacterial Infection and Female Sex in Cicatricial Trachoma Free
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Vicky Cevallos; John P. Whitcher; Muluken Melese; Wondu Alemayehu; Elizabeth Yi; Jaya D. Chidambaram; Scott Lee; Harsha Reddy; Bruce D. Gaynor; Thomas M. Lietman; Jeremy D. Keenan
Tags: conjunctiva, eyelid trichiasis, infections, trachoma
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5208-5212. doi:https://doi.org/10.1167/iovs.12-9984
Relationship between Clinical Macular Changes and Retinal Function in Age-Related Macular Degeneration Free
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Peter N. Dimitrov; Liubov D. Robman; Mary Varsamidis; Khin Zaw Aung; Galina Makeyeva; Lucy Busija; Algis J. Vingrys; Robyn H. Guymer
Tags: age-related macular degeneration, drusen, eye, vision, psychophysics
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5213-5220. doi:https://doi.org/10.1167/iovs.11-8958
Right and Left Correlation of Retinal Vessel Caliber Measurements in Anisometropic Children: Effect of Refractive Error Free
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Nichole Joachim; Elena Rochtchina; Ava Grace Tan; Thomas Hong; Paul Mitchell; Jie Jin Wang
Tags: anisometropia, child, refractive errors, retinal vascular caliber, eye
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5227-5230. doi:https://doi.org/10.1167/iovs.12-9422
Association between Ocular Dominance and Spherical/Astigmatic Anisometropia, Age, and Sex: Analysis of 1274 Hyperopic Individuals Free
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Stephan J. Linke; Julio Baviera; Gisbert Richard; Toam Katz
Tags: anisometropia, eye, hyperopia, ocular dominance, astigmatism
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5362-5369. doi:https://doi.org/10.1167/iovs.11-8781
Prevalence of Myopia and its Association with Body Stature and Educational Level in 19-Year-Old Male Conscripts in Seoul, South Korea Free
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Su-Kyung Jung; Jin Hae Lee; Hirohiko Kakizaki; Donghyun Jee
Tags: educational status, korea, myopia, prevalence
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5579-5583. doi:https://doi.org/10.1167/iovs.12-10106
Retinal Nerve Fiber Layer Thickness Reproducibility Using Seven Different OCT Instruments Free
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Luisa Pierro; Marco Gagliardi; Lorenzo Iuliano; Alessandro Ambrosi; Francesco Bandello
Tags: retinal nerve fiber layer
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5912-5920. doi:https://doi.org/10.1167/iovs.11-8644

Cornea

Mesenchymal Stem Cells in the Human Corneal Limbal Stroma Free
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Matthew James Branch; Khurram Hashmani; Permesh Dhillon; D. Rhodri E. Jones; Harminder Singh Dua; Andrew Hopkinson
Tags: cornea, flow cytometry, mesenchymal stem cells, keratocytes, cd34 antigens
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5109-5116. doi:https://doi.org/10.1167/iovs.11-8673
Long-Term Changes in Corneal Structure and Tear Inflammatory Mediators after Orthokeratology and LASIK Free
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Javier González-Pérez; César Villa-Collar; José Manuel González-Méijome; Nery García Porta; Manuel Ángel Parafita
Tags: cornea, inflammation mediators, keratomileusis, laser in situ, orthokeratology, lens (device)
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5301-5311. doi:https://doi.org/10.1167/iovs.11-9155
FK962 Promotes Neurite Elongation and Regeneration of Cultured Rat Trigeminal Ganglion Cells: Possible Involvement of GDNF Free
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Yayoi Kishimoto; Chiho Yabuta; Thomas R. Shearer; Mitsuyoshi Azuma
Tags: glial cell-line derived neurotrophic factor, neurites, trigeminal ganglion, neurons
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5312-5319. doi:https://doi.org/10.1167/iovs.11-8957
Presence and Physiologic Function of the Renin–Angiotensin System in Mouse Lacrimal Gland Free
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Saori Yaguchi; Yoko Ogawa; Shigeto Shimmura; Shin Hatou; Shigeru Nakamura; Takaaki Inaba; Toshihiro Imada; Yoko Ozawa; Yutaka Kawakami; Susumu Ishida; Kazuo Tsubota
Tags: fibroblasts, lacrimal gland, mice, renin-angiotensin system, angiotensin ii
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5416-5425. doi:https://doi.org/10.1167/iovs.12-9891
The Use of Fluorescent Quenching in Studying the Contribution of Evaporation to Tear Thinning Free
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Jason J. Nichols; P. Ewen King-Smith; Erich A. Hinel; Miru Thangavelu; Kelly K. Nichols
Tags: evaporation, fluorescein, fluorescence, mass or substance concentration per volume, tear film finding
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5426-5432. doi:https://doi.org/10.1167/iovs.12-10033
Correlations between Tear Cytokines, Chemokines, and Soluble Receptors and Clinical Severity of Dry Eye Disease Free
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Kyung-Sun Na; Jee-Won Mok; Ja Yeon Kim; Chang Rhe Rho; Choun-Ki Joo
Tags: chemokines, cytokine, dry eye syndromes, interleukin-17
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5443-5450. doi:https://doi.org/10.1167/iovs.11-9417
Confocal Comparison of Corneal Nerve Regeneration and Keratocyte Reaction between FS-LASIK, OUP-SBK, and Conventional LASIK Free
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Fengju Zhang; Shijing Deng; Ning Guo; Mengmeng Wang; Xuguang Sun
Tags: cornea, keratocytes, keratomileusis, laser in situ, nerve regeneration, surgical flaps
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5536-5544. doi:https://doi.org/10.1167/iovs.11-8786
Modeling the Effect of Forward Scatter and Aberrations on Visual Acuity after Endothelial Keratoplasty Free
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Jay W. McLaren; Sanjay V. Patel
Tags: keratoplasty, visual acuity, endothelium, descemet stripping endothelial keratoplasty, eye
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5545-5551. doi:https://doi.org/10.1167/iovs.12-10011
In Vitro Effects of Three Blood Derivatives on Human Corneal Epithelial Cells Free
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Vanesa Freire; Noelia Andollo; Jaime Etxebarria; Juan A. Durán; María-Celia Morales
Tags: cell proliferation, corneal epithelial cells, growth factor, reverse transcriptase polymerase chain reaction, gap junction protein
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5571-5578. doi:https://doi.org/10.1167/iovs.11-7340
Expression of Angiogenesis-Related Factors in Human Corneas after Cultivated Oral Mucosal Epithelial Transplantation Free
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Hung-Chi Jesse Chen; Lung-Kun Yeh; Yueh-Ju Tsai; Chyong-Huey Lai; Chi-Chun Chen; Jui-Yang Lai; Chi-Chin Sun; Grace Chang; Tsann-Long Hwang; Jan-Kan Chen; David Hui-Kang Ma
Tags: angiogenesis, angiogenesis factor, cornea, epithelium, oral mucous membrane
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5615-5623. doi:https://doi.org/10.1167/iovs.11-9293
Expression of Toll-Like Receptor 4 Contributes to Corneal Inflammation in Experimental Dry Eye Disease Free
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Hyun Soo Lee; Takaaki Hattori; Eun Young Park; William Stevenson; Sunil K. Chauhan; Reza Dana
Tags: cornea, dry eye syndromes, toll-like receptor 4, keratitis
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5632-5640. doi:https://doi.org/10.1167/iovs.12-9547
Comparison of Different Methods of Glycerol Preservation for Deep Anterior Lamellar Keratoplasty Eligible Corneas Free
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Jinyang Li; Shuai Shi; Xin Zhang; Shouxiang Ni; Yu Wang; Christine A Curcio; Wei Chen
Tags: cornea, glycerol, keratoplasty, body tissue
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5675-5685. doi:https://doi.org/10.1167/iovs.12-9936
Mesenchymal Stem Cells Derived from Human Limbal Niche Cells Free
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Gui-Gang Li; Ying-Ting Zhu; Hua-Tao Xie; Szu-Yu Chen; Scheffer C. G. Tseng
Tags: angiogenesis, fibroblasts, mesenchymal stem cells, stromal cells, collagenase
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5686-5697. doi:https://doi.org/10.1167/iovs.12-10300
Assessment of Vision-Related Quality of Life in Dry Eye Patients Free
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Meiyan Li; Lan Gong; William J. Chapin; Min Zhu
Tags: dry eye syndromes, quality of life, vision, questionnaires
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5722-5727. doi:https://doi.org/10.1167/iovs.11-9094
Mitochondrial Superoxide Anion Overproduction in Tet-mev-1 Transgenic Mice Accelerates Age-Dependent Corneal Cell Dysfunctions Free
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Hiromi Onouchi; Takamasa Ishii; Masaki Miyazawa; Yuichi Uchino; Kayo Yasuda; Phil S. Hartman; Kenji Kawai; Kazuo Tsubota; Naoaki Ishii
Tags: cornea, eye, mice, mice, transgenic, mitochondria
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5780-5787. doi:https://doi.org/10.1167/iovs.12-9573
Decline in DJ-1 and Decreased Nuclear Translocation of Nrf2 in Fuchs Endothelial Corneal Dystrophy Free
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Maya S. Bitar; Cailing Liu; Alireza Ziaei; Yuming Chen; Thore Schmedt; Ula V. Jurkunas
Tags: antibodies, catabolism, cell nucleus, chronic exertional compartment syndrome, disease susceptibility
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5806-5813. doi:https://doi.org/10.1167/iovs.12-10119
In Vitro Amyloid Aggregate Forming Ability of TGFBI Mutants that Cause Corneal Dystrophies Free
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Gary Hin-Fai Yam; Kaijie Wang; Vishal Jhanji; Kwong-Wai Choy; Larry Baum; Chi-Pui Pang
Tags: amyloid, hereditary corneal dystrophy, mutation, peptides, proteins
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5890-5898. doi:https://doi.org/10.1167/iovs.11-9068
Monitoring of Cornea Elastic Properties Changes during UV-A/Riboflavin-Induced Corneal Collagen Cross-Linking using Supersonic Shear Wave Imaging: A Pilot Study Free
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Thu-Mai Nguyen; Jean-François Aubry; David Touboul; Mathias Fink; Jean-Luc Gennisson; Jeremy Bercoff; Mickael Tanter
Tags: cornea, corneal collagen cross-linking, diagnostic imaging, riboflavin, ultraviolet a radiation
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5948-5954. doi:https://doi.org/10.1167/iovs.11-9142

Eye Movements, Strabismus, Amblyopia and Neuro-ophthalmology

Differences in Gene Expression between Strabismic and Normal Human Extraocular Muscles Free
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Amy L. Altick; Cheng-Yuan Feng; Karen Schlauch; L. Alan Johnson; Christopher S. von Bartheld
Tags: gene expression, genes, muscle, muscle of orbit, polymerase chain reaction
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5168-5177. doi:https://doi.org/10.1167/iovs.12-9785
Eye Position Stability in Amblyopia and in Normal Binocular Vision Free
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Esther G. González; Agnes M. F. Wong; Ewa Niechwiej-Szwedo; Luminita Tarita-Nistor; Martin J. Steinbach
Tags: amblyopia, eye, vision, binocular
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5386-5394. doi:https://doi.org/10.1167/iovs.12-9941
Diagnostic Ability of Retinal Nerve Fiber Layer Thickness Measurements and Neurologic Hemifield Test to Detect Chiasmal Compression Free
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Chan Hee Moon; Si Hyung Lee; Bum-Tae Kim; Sun Chul Hwang; Young-Hoon Ohn; Tae Kwann Park
Tags: compression, retinal nerve fiber layer, glaucoma
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5410-5415. doi:https://doi.org/10.1167/iovs.12-9905
Characterization of Pupil Responses to Blue and Red Light Stimuli in Autosomal Dominant Retinitis Pigmentosa due to NR2E3 Mutation Free
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Aki Kawasaki; Sylvain V. Crippa; Randy Kardon; Lorette Leon; Christian Hamel
Tags: mutation, pupil reaction, retinitis pigmentosa, blue light, rod photoreceptors
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5562-5569. doi:https://doi.org/10.1167/iovs.12-10230
Chromatic Pupillometry Dissects Function of the Three Different Light-Sensitive Retinal Cell Populations in RPE65 Deficiency Free
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Birgit Lorenz; Elisabeth Strohmayr; Steffen Zahn; Christoph Friedburg; Martin Kramer; Markus Preising; Knut Stieger
Tags: pupil reaction, pupillometry, retinal cone, rod photoreceptors, pupil
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5641-5652. doi:https://doi.org/10.1167/iovs.12-9974
Albino Mice as an Animal Model for Infantile Nystagmus Syndrome Free
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Ghislaine L. Traber; Chien-Cheng Chen; Ying-Yu Huang; Marcella Spoor; Jeanine Roos; Maarten A. Frens; Dominik Straumann; Christian Grimm
Tags: albinism, animal model, mice, pathologic nystagmus, syndrome
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5737-5747. doi:https://doi.org/10.1167/iovs.12-10137
A Perioculomotor Nitridergic Population in the Macaque and Cat Free
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Jonathan T. Erichsen; Paul J. May
Tags: adaptive testing, cats, cercopithecidae, chloramphenicol o-acetyltransferase, macaca
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5751-5761. doi:https://doi.org/10.1167/iovs.12-10287
Individual Differences in Binocular Coordination Are Uncovered by Directly Comparing Monocular and Binocular Reading Conditions Free
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Stephanie Jainta; Wolfgang Jaschinski
Tags: eye, eye movement, reading (activity), strabismus
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5762-5769. doi:https://doi.org/10.1167/iovs.12-9707

Genetics

Exclusion of RPGRIP1 ins44 from Primary Causal Association with Early-Onset Cone–Rod Dystrophy in Dogs Free
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Tatyana Kuznetsova; Simone Iwabe; Kathleen Boesze-Battaglia; Sue Pearce-Kelling; Yim Chang-Min; Kendra McDaid; Keiko Miyadera; Andras Komaromy; Gustavo D. Aguirre
Tags: dog, domestic, retinitis pigmentosa, progressive cone-rod dystrophy, electroretinography, mutation
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5486-5501. doi:https://doi.org/10.1167/iovs.12-10178
Genome-Wide Expression Profiling of Patients with Primary Open Angle Glaucoma Free
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Dilek Colak; Jose Morales; Thomas M. Bosley; Albandary Al-Bakheet; Banan AlYounes; Namik Kaya; Khaled K. Abu-Amero
Tags: gene expression profiling, genome, open-angle glaucoma, genes
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5899-5904. doi:https://doi.org/10.1167/iovs.12-9634

Glaucoma

Comparison of Two Spectral Domain Optical Coherence Tomography Devices for Angle-Closure Assessment Free
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Desmond T. Quek; Arun K. Narayanaswamy; Tin A. Tun; Hla M. Htoon; Mani Baskaran; Shamira A. Perera; Tin Aung
Tags: diagnostic imaging, eye, gonioscopy, optical coherence tomography, sclera
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5131-5136. doi:https://doi.org/10.1167/iovs.12-10132
Toxicity Evaluation of Antiglaucoma Drugs Using Stratified Human Cultivated Corneal Epithelial Sheets Free
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Suguru Nakagawa; Tomohiko Usui; Seiichi Yokoo; Sachiko Omichi; Mikiko Kimakura; Yosai Mori; Kazunori Miyata; Makoto Aihara; Shiro Amano; Makoto Araie
Tags: antiglaucoma agents, bacterial artificial chromosomes, blood alcohol concentration, bronchioloalveolar carcinoma, cornea
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5154-5160. doi:https://doi.org/10.1167/iovs.12-9685
Morphometric Analysis of Aqueous Humor Outflow Structures with Spectral-Domain Optical Coherence Tomography Free
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Andrew W. Francis; Larry Kagemann; Gadi Wollstein; Hiroshi Ishikawa; Steven Folz; Darryl R. Overby; Ian A. Sigal; Bo Wang; Joel S. Schuman
Tags: aqueous humor, casts, surgical, eye, optical coherence tomography, corrosion casting
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5198-5207. doi:https://doi.org/10.1167/iovs.11-9229
Quantitative Mapping of Collagen Fiber Orientation in Non-glaucoma and Glaucoma Posterior Human Sclerae Free
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Jacek K. Pijanka; Baptiste Coudrillier; Kimberly Ziegler; Thomas Sorensen; Keith M. Meek; Thao D. Nguyen; Harry A. Quigley; Craig Boote
Tags: collagen fiber, glaucoma, sclera, diagnostic radiologic examination, anisotropy
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5258-5270. doi:https://doi.org/10.1167/iovs.12-9705
Transforming Growth Factor-β2 Induces Synthesis and Secretion of Endothelin-1 in Human Trabecular Meshwork Cells Free
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Cynthia L. Von Zee; Kelly A. Langert; Evan B. Stubbs, Jr
Tags: bodily secretions, endothelin-1, trabecular meshwork, rna, messenger, actins
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5279-5286. doi:https://doi.org/10.1167/iovs.11-9289
Regional Variations in Mechanical Strain in the Posterior Human Sclera Free
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Massimo A. Fazio; Rafael Grytz; Luigi Bruno; Michael J. A. Girard; Stuart Gardiner; Christopher A. Girkin; J. Crawford Downs
Tags: eye, sclera
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5326-5333. doi:https://doi.org/10.1167/iovs.12-9668
Validation of Point-Wise Exponential Regression to Measure the Decay Rates of Glaucomatous Visual Fields Free
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Parham Azarbod; Dennis Mock; Elena Bitrian; Abdelmonem A. Afifi; Fei Yu; Kouros Nouri-Mahdavi; Anne L. Coleman; Joseph Caprioli
Tags: glaucoma, visual fields
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5403-5409. doi:https://doi.org/10.1167/iovs.12-9930
The Association between Retinal Vessel Diameter and Retinal Nerve Fiber Layer Thickness in Asymmetric Normal Tension Glaucoma Patients Free
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Joon Mo Kim; Mo Sae Kim; Hyo Ju Jang; Ki Ho Park; Joseph Caprioli
Tags: arteriole, diameter, glaucoma, low tension glaucoma, retinal nerve fiber layer
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5609-5614. doi:https://doi.org/10.1167/iovs.12-9783
Changes in Optic Nerve Head Circulation in Response to Vasoactive Agents: Intereye Comparison in Monkeys with Experimental Unilateral Glaucoma Free
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Chihiro Mayama; Kiyoshi Ishii; Takashi Ota; Atsuo Tomidokoro; Makoto Araie
Tags: cercopithecidae, eye, glaucoma, optic disk, vasoactive agents
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5771-5778. doi:https://doi.org/10.1167/iovs.12-9765
Influence of Anterior Segment Power on the Scan Path and RNFL Thickness Using SD-OCT Free
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Nimesh B. Patel; Brenda Garcia; Ronald S. Harwerth
Tags: retinal nerve fiber layer, contact lenses
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5788-5798. doi:https://doi.org/10.1167/iovs.12-9937
Laminar Displacement and Prelaminar Tissue Thickness Change after Glaucoma Surgery Imaged with Optical Coherence Tomography Free
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Alexandre S. C. Reis; Neil O'Leary; Miriam J. Stanfield; Lesya M. Shuba; Marcelo T. Nicolela; Balwantray C. Chauhan
Tags: body tissue, glaucoma surgery, intraocular pressure, optic disk, optical coherence tomography
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5819-5826. doi:https://doi.org/10.1167/iovs.12-9924
Determinants of Ganglion Cell–Inner Plexiform Layer Thickness Measured by High-Definition Optical Coherence Tomography Free
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Victor T. Koh; Yih-Chung Tham; Carol Y. Cheung; Wan-Ling Wong; Mani Baskaran; Seang-Mei Saw; Tien Y. Wong; Tin Aung
Tags: ganglia, optical coherence tomography, retinal nerve fiber layer, eye, glaucoma
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5853-5859. doi:https://doi.org/10.1167/iovs.12-10414
Wavelength-Dependent Change of Retinal Nerve Fiber Layer Reflectance in Glaucomatous Retinas Free
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Xiang-Run Huang; Ye Zhou; Robert W. Knighton; Wei Kong; William J. Feuer
Tags: glaucoma, retina, retinal nerve fiber layer, cytoskeleton
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5869-5876. doi:https://doi.org/10.1167/iovs.12-10001
Moving from PROMs to POEMs for Glaucoma Care: A Qualitative Scoping Exercise Free
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John E. A. Somner; Freda Sii; Rupert R. Bourne; Vinette Cross; Jennifer M. Burr; Peter Shah
Tags: exercise, glaucoma, poems syndrome, questionnaires
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5940-5947. doi:https://doi.org/10.1167/iovs.12-10223
A Neurobehavioral Analysis of the Prevention of Visual Impairment in the DBA/2J Mouse Model of Glaucoma Free
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Aimée A. Wong; Richard E. Brown
Tags: cell count, glaucoma, mice, superior colliculus, visual impairment
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5956-5966. doi:https://doi.org/10.1167/iovs.12-10020

Immunology and Microbiology

Screening of Ocular Enterobacteriaceae Isolates for Presence of Chromosomal blaNDM-1 and ESBL Genes: A 2-Year Study at a Tertiary Eye Care Center Free
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Murali Sowmiya; Jambulingam Malathi; Hajib Naraharirao Madhavan
Tags: enterobacteriaceae, extended-spectrum beta lactamases, genes, screening, prevalence
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5251-5257. doi:https://doi.org/10.1167/iovs.12-10467
Suppression of Murine Experimental Autoimmune Optic Neuritis by Mature Dendritic Cells Transfected with Calcitonin Gene–Related Peptide Gene Free
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Ryusaku Matsuda; Takeshi Kezuka; Chiharu Nishiyama; Yoshihiko Usui; Yoshimichi Matsunaga; Yoko Okunuki; Naoyuki Yamakawa; Hideoki Ogawa; Ko Okumura; Hiroshi Goto
Tags: autoimmune diseases, calcitonin gene-related peptide, mice, optic neuritis, immunization
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5475-5485. doi:https://doi.org/10.1167/iovs.12-9935
Suppression of Murine Experimental Autoimmune Optic Neuritis by Mature Dendritic Cells Transfected with Calcitonin Gene–Related Peptide Gene Free
PDF
Ryusaku Matsuda; Takeshi Kezuka; Chiharu Nishiyama; Yoshihiko Usui; Yoshimichi Matsunaga; Yoko Okunuki; Naoyuki Yamakawa; Hideoki Ogawa; Ko Okumura; Hiroshi Goto
Tags: autoimmune diseases, calcitonin gene-related peptide, mice, optic neuritis, immunization
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5475-5485. doi:https://doi.org/10.1167/iovs.12-9935
Comparative Ocular Microbial Communities in Humans with and without Blepharitis Free
PDF
Se Hee Lee; Doo Hwan Oh; Ji Young Jung; Jae Chan Kim; Che Ok Jeon
Tags: blepharitis, community, pyrosequencing, rna, ribosomal, 16s
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5585-5593. doi:https://doi.org/10.1167/iovs.12-9922
Biofilm-Forming Capacity of Staphylococcus epidermidis , Staphylococcus aureus , and Pseudomonas aeruginosa from Ocular Infections Free
PDF
Wenbo Hou; Xuguang Sun; Zhiqun Wang; Yang Zhang
Tags: bacteria, biofilms, bone plates, eye infections, pseudomonas aeruginosa
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5624-5631. doi:https://doi.org/10.1167/iovs.11-9114
Decreased microRNA-155 Expression in Ocular Behcet's Disease but Not in Vogt Koyanagi Harada Syndrome Free
PDF
Qingyun Zhou; Xiang Xiao; Chaokui Wang; Xuedong Zhang; Fuzhen Li; Yan Zhou; Aize Kijlstra; Peizeng Yang
Tags: behcet syndrome, interleukin-6, micrornas, uveitis, uveomeningoencephalitic syndrome
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5665-5674. doi:https://doi.org/10.1167/iovs.12-9832

Lens

Changes in Lens Power in Singapore Chinese Children during Refractive Development Free
PDF
Rafael Iribarren; Ian G. Morgan; Yiong Huak Chan; Xiaoyu Lin; Seang-Mei Saw
Tags: child, lens (device), lens, crystalline, myopia, singapore
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5124-5130. doi:https://doi.org/10.1167/iovs.12-9637

Low Vision

Standardized Assessment of Reading Performance: The New International Reading Speed Texts IReST Free
PDF
Susanne Trauzettel-Klosinski; Klaus Dietz; the IReST Study Group
Tags: languages, reading (activity), reading speed
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5452-5461. doi:https://doi.org/10.1167/iovs.11-8284
Peripheral Vision of Youths with Low Vision: Motion Perception, Crowding, and Visual Search Free
PDF
Duje Tadin; Jeffrey B. Nyquist; Kelly E. Lusk; Anne L. Corn; Joseph S. Lappin
Tags: motion, motion perception, visual impairment, visual search, vision
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5860-5868. doi:https://doi.org/10.1167/iovs.12-10350

Multidisciplinary Ophthalmic Imaging

Effect of Image Compression and Resolution on Retinal Vascular Caliber Free
PDF
Thomas W. Pauli; Sapna Gangaputra; Larry D. Hubbard; Dennis W. Thayer; Charles S. Chandler; Qian Peng; Ashwini Narkar; Nicola J. Ferrier; Ronald P. Danis
Tags: image compression, retinal vascular caliber, compression
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5117-5123. doi:https://doi.org/10.1167/iovs.12-9643
A Novel Technique of Adjusting Segmentation Boundary Layers to Achieve Comparability of Retinal Thickness and Volumes between Spectral Domain and Time Domain Optical Coherence Tomography Free
PDF
Colin S. H. Tan; Kelvin Z. Li; Tock Han Lim
Tags: optical coherence tomography, diagnostic imaging
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5515-5519. doi:https://doi.org/10.1167/iovs.12-9868
Behavior of SD-OCT–Detected Hyperreflective Foci in the Retina of Anti-VEGF–Treated Patients with Diabetic Macular Edema Free
PDF
Carsten Framme; Paul Schweizer; Manfred Imesch; Sebastian Wolf; Ute Wolf-Schnurrbusch
Tags: anti-vascular endothelial growth factor therapy, diabetic macular edema, palmar-plantar erythrodysesthesia syndrome, retina, heart failure
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5814-5818. doi:https://doi.org/10.1167/iovs.12-9950

Nantotechnology and Regenerative Medicine

Intravitreal Silicon-Based Quantum Dots as Neuroprotective Factors in a Model of Retinal Photoreceptor Degeneration Free
PDF
Jeffrey L. Olson; Raul Velez-Montoya; Naresh Mandava; Conrad R. Stoldt
Tags: photoreceptors, quantum dots, retina, silicon, tissue degeneration
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5713-5721. doi:https://doi.org/10.1167/iovs.12-9745

Physiology and Pharmacology

Unoprostone Isopropyl and Metabolite M1 Activate BK Channels and Prevent ET-1–Induced [Ca2+]i Increases in Human Trabecular Meshwork and Smooth Muscle Free
PDF
John Cuppoletti; Danuta H. Malinowska; Kirti P. Tewari; Jayati Chakrabarti; Ryuji Ueno
Tags: cell membrane, endothelin-1, metabolites, unoprostone isopropyl, transcriptional activation
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5178-5189. doi:https://doi.org/10.1167/iovs.11-9046
Differential Effects of Trabecular Meshwork Stiffness on Outflow Facility in Normal Human and Porcine Eyes Free
PDF
Lucinda J. Camras; W. Daniel Stamer; David Epstein; Pedro Gonzalez; Fan Yuan
Tags: eye, suidae, trabecular meshwork, heterogeneity of variance
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5242-5250. doi:https://doi.org/10.1167/iovs.12-9825
Pharmacologic Manipulation of Conventional Outflow Facility in Ex Vivo Mouse Eyes Free
PDF
Alexandra Boussommier-Calleja; Jacques Bertrand; David F. Woodward; C. Ross Ethier; W. Daniel Stamer; Darryl R. Overby
Tags: eye, mice, perfusion, pharmacology
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5838-5845. doi:https://doi.org/10.1167/iovs.12-9923

Retina

Abnormal Retinal Vascular Reactivity in Individuals with Impaired Glucose Tolerance: A Preliminary Study Free
PDF
Sunni R. Patel; Srikanth Bellary; Lu Qin; George M. Balanos; David McIntyre; Doina Gherghel
Tags: cardiovascular diseases, glucose intolerance
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5102-5108. doi:https://doi.org/10.1167/iovs.12-9512
Fundus Autofluorescence Findings in a Mouse Model of Retinal Detachment Free
PDF
Roberta Secondi; Jian Kong; Anna M. Blonska; Giovanni Staurenghi; Janet R. Sparrow
Tags: fluorescence, fundus autofluorescence imaging, mice, retinal detachment, retina
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5190-5197. doi:https://doi.org/10.1167/iovs.12-9672
Ocular Pharmacokinetics of Bevacizumab in Vitrectomized Eyes with Silicone Oil Tamponade Free
PDF
Yu Xu; Yongsheng You; Wennan Du; Chunhui Zhao; Jie Li; Jianbo Mao; Hao Chen; Lingyun Cheng
Tags: bevacizumab, eye, silicone oils, pharmacokinetics
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5221-5226. doi:https://doi.org/10.1167/iovs.12-9702
Microarray Analysis of Murine Retinal Light Damage Reveals Changes in Iron Regulatory, Complement, and Antioxidant Genes in the Neurosensory Retina and Isolated RPE Free
PDF
Majda Hadziahmetovic; Usha Kumar; Ying Song; Steven Grieco; Delu Song; Yafeng Li; John W. Tobias; Joshua L. Dunaief
Tags: antioxidants, complement system proteins, genes, iron, retina
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5231-5241. doi:https://doi.org/10.1167/iovs.12-10204
Effect of Angle of Incidence on Macular Thickness and Volume Measurements Obtained by Spectral-Domain Optical Coherence Tomography Free
PDF
Amirhossein Hariri; Sun Young Lee; Humberto Ruiz-Garcia; Muneeswar Gupta Nittala; Florian M. Heussen; Srinivas R. Sadda
Tags: incidence, optical coherence tomography, volume, pupil
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5287-5291. doi:https://doi.org/10.1167/iovs.12-9767
Chemokine Receptor Expression in Peripheral Blood Monocytes from Patients with Neovascular Age-Related Macular Degeneration Free
PDF
Michelle Grunin; Tal Burstyn-Cohen; Shira Hagbi-Levi; Amnon Peled; Itay Chowers
Tags: chemokine receptors, exudative age-related macular degeneration, monocytes, chemokines
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5292-5300. doi:https://doi.org/10.1167/iovs.11-9165
Retinal Vessel Oxygen Saturation in Healthy Individuals Free
PDF
Asbjorg Geirsdottir; Olafur Palsson; Sveinn Hakon Hardarson; Olof Birna Olafsdottir; Jona Valgerdur Kristjansdottir; Einar Stefánsson
Tags: oxygen saturation measurement, retinal vessels, arteriole, venule, oxygen analyzer, device
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5433-5442. doi:https://doi.org/10.1167/iovs.12-9912
Longitudinal Changes in Retinal Nerve Fiber Layer Thickness after Vitrectomy for Rhegmatogenous Retinal Detachment Free
PDF
Yeon-Hee Lee; Jong-Eun Lee; Yong-IL Shin; Kyung-Mu Lee; Young-Joon Jo; Jung-Yeul Kim
Tags: eye, retinal detachment, retinal nerve fiber layer, rhegmatogenous retinal detachment, vitrectomy
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5471-5474. doi:https://doi.org/10.1167/iovs.12-9782
Quantitative Morphometry of Perifoveal Capillary Networks in the Human Retina Free
PDF
Geoffrey Chan; Chandrakumar Balaratnasingam; Paula K. Yu; William H. Morgan; Ian L. McAllister; Stephen J. Cringle; Dao-Yi Yu
Tags: blood capillaries, retina, donors
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5502-5514. doi:https://doi.org/10.1167/iovs.12-10265
Antibody-Mediated Retinal Pericyte Injury: Implications for Diabetic Retinopathy Free
PDF
Yan Li; Dawn Smith; Qing Li; Nader Sheibani; Suber Huang; Timothy Kern; Ram H. Nagaraj; Feng Lin
Tags: antibodies, pericytes, diabetic retinopathy, cytotoxicity, wounds and injuries
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5520-5526. doi:https://doi.org/10.1167/iovs.12-10010
Transcorneal Electrical Stimulation Shows Neuroprotective Effects in Retinas of Light-Exposed Rats Free
PDF
Andreas Schatz; Blanca Arango-Gonzalez; Dominik Fischer; Heike Enderle; Sylvia Bolz; Tobias Röck; Lubka Naycheva; Christian Grimm; André Messias; Eberhart Zrenner; Karl Ulrich Bartz-Schmidt; Gabriel Willmann; Florian Gekeler
Tags: electric stimulation, electroretinography, in situ nick-end labeling, neuroprotective effect, rats
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5552-5561. doi:https://doi.org/10.1167/iovs.12-10037
RPGR-Associated Retinal Degeneration in Human X-Linked RP and a Murine Model Free
PDF
Wei Chieh Huang; Alan F. Wright; Alejandro J. Roman; Artur V. Cideciyan; Forbes D. Manson; Dina Y. Gewaily; Sharon B. Schwartz; Sam Sadigh; Maria P. Limberis; Peter Bell; James M. Wilson; Anand Swaroop; Samuel G. Jacobson
Tags: mice, retinal cone, retinal degeneration, retinal diseases, rod photoreceptors
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5594-5608. doi:https://doi.org/10.1167/iovs.12-10070
Aldose Reductase Deficiency Reduced Vascular Changes in Neonatal Mouse Retina in Oxygen-Induced Retinopathy Free
PDF
Zhong Jie Fu; Suk-Yee Li; Norbert Kociok; David Wong; Sookja K. Chung; Amy C. Y. Lo
Tags: aldehyde reductase, androgen-insensitivity syndrome, immunohistochemistry, mice, neovascularization, pathologic
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5698-5712. doi:https://doi.org/10.1167/iovs.12-10122
Quantitative Confocal Imaging of the Retinal Microvasculature in the Human Retina Free
PDF
Priscilla Ern Zhi Tan; Paula K. Yu; Chandrakumar Balaratnasingam; Stephen J. Cringle; William H. Morgan; Ian L. McAllister; Dao-Yi Yu
Tags: blood capillaries, diagnostic imaging, retina, retinal vasculature, microvascular network
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5728-5736. doi:https://doi.org/10.1167/iovs.12-10017
Does Retinal Vascular Geometry Vary with Cardiac Cycle? Free
PDF
Hao Hao; Muhammad B. Sasongko; Tien Y. Wong; Mohd Zulfaezal Che Azemin; Behzad Aliahmad; Lauren Hodgson; Ryo Kawasaki; Carol Y. Cheung; Jie Jin Wang; Dinesh K. Kumar
Tags: cardiac cycle, diameter, retinal vessels
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5799-5805. doi:https://doi.org/10.1167/iovs.11-9326
Genetic, Behavioral, and Sociodemographic Risk Factors for Second Eye Progression in Age-Related Macular Degeneration Free
PDF
Yara T. E. Lechanteur; Johannes P. H. van de Ven; Dzenita Smailhodzic; Camiel J. F. Boon; B. Jeroen Klevering; Sascha Fauser; Joannes M. M. Groenewoud; Gert-Jan van der Wilt; Anneke I. den Hollander; Carel B. Hoyng
Tags: age-related macular degeneration, eye, genetics, risk factors, body mass index procedure
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5846-5852. doi:https://doi.org/10.1167/iovs.11-7731
Effect of Vitrectomy on Aqueous VEGF Concentration and Pharmacokinetics of Bevacizumab in Macaque Monkeys Free
PDF
Masashi Kakinoki; Osamu Sawada; Tomoko Sawada; Yoshitsugu Saishin; Hajime Kawamura; Masahito Ohji
Tags: bevacizumab, macaca, mass or substance concentration per volume, pharmacokinetics, vascular endothelial growth factor a
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5877-5880. doi:https://doi.org/10.1167/iovs.12-10164
Increased Prostaglandin E2 (PGE2) Levels in Proliferative Diabetic Retinopathy, and Correlation with VEGF and Inflammatory Cytokines Free
PDF
Scott D. Schoenberger; Stephen J. Kim; Jinsong Sheng; Kasra A. Rezaei; Maziar Lalezary; Edward Cherney
Tags: cytokine, diabetic retinopathy, dinoprostone, proliferative diabetic retinopathy, prostaglandins
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5906-5911. doi:https://doi.org/10.1167/iovs.12-10410

Retinal Cell Biology

Development of Retinal Pigment Epithelium from Human Parthenogenetic Embryonic Stem Cells and MicroRNA Signature Free
PDF
Wen-Bo Li; Yun-Shan Zhang; Zhen-Yu Lu; Li-Jie Dong; Fei E. Wang; Rong Dong; Xiao-Rong Li
Tags: micrornas, retinal pigment cell, embryonic stem cells, retinal pigment epithelium
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5334-5343. doi:https://doi.org/10.1167/iovs.12-8303
Induction of Autophagy and Cell Death by Tamoxifen in Cultured Retinal Pigment Epithelial and Photoreceptor Cells Free
PDF
Kyung Sook Cho; Young Hee Yoon; Jeong A. Choi; Sook-Jeong Lee; Jae-Young Koh
Tags: autophagy, cell death, photoreceptors, pigment, tamoxifen
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5344-5353. doi:https://doi.org/10.1167/iovs.12-9827
Moderately Reduced ATP Levels Promote Oxidative Stress and Debilitate Autophagic and Phagocytic Capacities in Human RPE Cells Free
PDF
Florian Schütt; Sebastian Aretz; Gerd U. Auffarth; Jürgen Kopitz
Tags: atractyloside, oxidative stress, proteins, retinal pigment cell, glutathione
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5354-5361. doi:https://doi.org/10.1167/iovs.12-9845
Attenuation of EphrinB2 Reverse Signaling Decreases Vascularized Area and Preretinal Vascular Tuft Formation in the Murine Model of Oxygen-Induced Retinopathy Free
PDF
Alyssa C. Taylor; Thomas A. Mendel; Katelyn E. Mason; Katherine E. Degen; Paul A. Yates; Shayn M. Peirce
Tags: attenuation, blood capillaries, mice, oxygen, retina
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5462-5470. doi:https://doi.org/10.1167/iovs.11-8599
Activated Blood Coagulation Factor X (FXa) Induces Angiogenic Growth Factor Expression in Human Retinal Pigment Epithelial Cells Free
PDF
Margrit Hollborn; Leon Kohen; Cornelia Werschnik; Lore Tietz; Peter Wiedemann; Andreas Bringmann
Tags: angiogenesis, factor x, growth factor, retinal pigment cell, vascular endothelial growth factor a
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5930-5939. doi:https://doi.org/10.1167/iovs.11-9214

Visual Neuroscience

Myopia Progression in Children Is Linked with Reduced Foveal mfERG Response Free
PDF
Wing-cheung Ho; Chea-su Kee; Henry Ho-lung Chan
Tags: child, myopia
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5320-5325. doi:https://doi.org/10.1167/iovs.12-10185
Effect of Contrast, Stimulus Density, and Viewing Distance on Multifocal Steady-State Visual Evoked Potentials (MSVs) Free
PDF
Siti N. Abdullah; Nada Aldahlawi; Yanti Rosli; Vaegan; Mei Ying Boon; Ted Maddess
Tags: evoked potentials, visual, steady state, spatial frequency
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5527-5535. doi:https://doi.org/10.1167/iovs.11-9325
Flash Responses of Mouse Rod Photoreceptors in the Isolated Retina and Corneal Electroretinogram: Comparison of Gain and Kinetics Free
PDF
Hanna Heikkinen; Frans Vinberg; Marja Pitkänen; Bertel Kommonen; Ari Koskelainen
Tags: cornea, electroretinography, kinetics, mice, retina
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5653-5664. doi:https://doi.org/10.1167/iovs.12-9678
Neural and Vascular Responses to Fused Binocular Stimuli:
A VEP and fNIRS Study Free
PDF
Sobanawartiny Wijeakumar; Uma Shahani; Daphne L. McCulloch; William A. Simpson
Tags: evoked potentials, visual, hyperbaric oxygenation
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5881-5889. doi:https://doi.org/10.1167/iovs.12-10399

Clinical Trials

Use of the Argus II Retinal Prosthesis to Improve Visual Guidance of Fine Hand Movements Free
PDF
Michael P. Barry; Gislin Dagnelie; Argus II Study Group
Tags: hand, prostheses, visual prosthesis, vision
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5095-5101. doi:https://doi.org/10.1167/iovs.12-9536
A Randomized, Controlled Trial of an Intervention Promoting Cataract Surgery Acceptance in Rural China: The Guangzhou Uptake of Surgery Trial (GUSTO) Free
PDF
Tianyu Liu; Nathan Congdon; Xixi Yan; Ling Jin; Ying Wu; David Friedman; Mingguang He
Tags: cataract, cataract surgery, china, randomized controlled trial, surgical procedures, operative
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5271-5278. doi:https://doi.org/10.1167/iovs.12-9798

Letters to the Editor

Author Response: Is Drusen Area Really So Important? Free
PDF
Thomas Friberg; Richard Bilonick; Peter Brennen
Tags: drusen
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5137-5138. doi:https://doi.org/10.1167/iovs.12-10282
Comparative Resilience of Clinical Perimetric Tests to Induced Levels of Intraocular Straylight Free
PDF
Marta Gonzalez-Hernandez; Manuel Gonzalez de la Rosa
Tags: perimetry
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5748. doi:https://doi.org/10.1167/iovs.12-10445
Author Response: Comparative Resilience of Clinical Perimetric Tests to Induced Levels of Intraocular Straylight Free
PDF
Ciara Bergin; Justyna D. Oleszczuk; Eamon Sharkawi
Tags: perimetry
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5749. doi:https://doi.org/10.1167/iovs.12-10601
Nonspecific PCR Amplification of CRYBB2-Pseudogene Leads to Misconception of Natural Variation as Mutation Free
PDF
K. Dinesh Kumar; G. Senthil Kumar; S. T. Santhiya
Tags: amplification, misconceptions, mutation, polymerase chain reaction, pseudogenes
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5770. doi:https://doi.org/10.1167/iovs.12-10575
Author Response: Nintendo Wii Remote Controllers for Head Posture Measurement—Accuracy, Validity, and Reliability of the Infrared Optical Head Tracker Letters Free
PDF
Jongshin Kim; Kyoung Won Nam; Ik Gyu Jang; Hee Kyung Yang; Kwang Gi Kim; Jeong–Min Hwang
Tags: optics, posture, reliability, validity of results
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5779. doi:https://doi.org/10.1167/iovs.12-10558
Author Response: Analysis of the Use of Multiple Comparison Corrections in Ophthalmology Research Free
PDF
Andrew W. Stacey; Craig N. Czyz
Tags: ophthalmology
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5955. doi:https://doi.org/10.1167/iovs.12-10642

Erratum

Erratum Free
PDF
Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5451. doi:https://doi.org/10.1167/iovs.11-8538a
Erratum Free
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Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5584. doi:https://doi.org/10.1167/iovs.12-9439a
Erratum Free
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Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5905. doi:https://doi.org/10.1167/iovs.12-9713a
Erratum Free
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Investigative Ophthalmology & Visual Science August 2012, Vol.53, 5975. doi:https://doi.org/10.1167/iovs.12-9878a
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