Select a back issue
Select a back issue
  • Alerts
    User Alerts
    You are adding an alert for:
    Investigative Ophthalmology & Visual Science
    You will receive an email whenever new content is published in the Investigative Ophthalmology & Visual Science. You can manage this and all other alerts in My Account
    The alert will be sent to:
    ×
    This feature is available to authenticated users only.
    Sign In or Create an Account ×

Research Highlight

Quantifying Structures in the Ocular Fundus Free
PDF
Douglas R. Anderson; Claude Burgoyne
Investigative Ophthalmology & Visual Science July 2012, Vol.53, 4531. doi:10.1167/iovs.12-10253

Anatomy and Pathology/Oncology

JARID1B Protein Expression and Prognostic Implications in Uveal Melanoma Free
PDF
Patrik Radberger; Agatha Radberger; Vladimir J. N. Bykov; Stefan Seregard; Mario A. Economou
Tags: intraocular melanoma, melanoma, neoplasms, proteins
Investigative Ophthalmology & Visual Science July 2012, Vol.53, 4442-4449. doi:10.1167/iovs.11-9296
Impact of Repeated Topical-Loaded Manganese-Enhanced MRI on the Mouse Visual System Free
PDF
Shu-Wei Sun; Tiffany Thiel; Hsiao-Fang Liang
Tags: magnetic resonance imaging, manganese, mice, optic nerve, visual system
Investigative Ophthalmology & Visual Science July 2012, Vol.53, 4699-4709. doi:10.1167/iovs.12-9715

Biochemistry and Molecular Biology

Ceramide Kinase-Like (CERKL) Interacts with Neuronal Calcium Sensor Proteins in the Retina in a Cation-Dependent Manner Free
PDF
Mariela J. Nevet; Sharon Vekslin; Alexander M. Dizhoor; Elena V. Olshevskaya; Rotem Tidhar; Anthony H. Futerman; Tamar Ben-Yosef
Tags: calcium, cations, ceramides, phosphotransferases, proteins
Investigative Ophthalmology & Visual Science July 2012, Vol.53, 4565-4574. doi:10.1167/iovs.12-9770
Leber's Hereditary Optic Neuropathy Is Associated with the T3866C Mutation in Mitochondrial ND1 Gene in Three Han Chinese Families Free
PDF
Xiangtian Zhou; Yaping Qian; Juanjuan Zhang; Yi Tong; Pingping Jiang; Min Liang; Xianning Dai; Huihui Zhou; Fuxin Zhao; Yanchun Ji; Jun Qin Mo; Jia Qu; Min-Xin Guan
Tags: cell lines, chinese (other dialects), chinese people, dna, mitochondrial, family
Investigative Ophthalmology & Visual Science July 2012, Vol.53, 4586-4594. doi:10.1167/iovs.11-9109
Surface Chemistry Study of the Interactions of Pharmaceutical Ingredients with Human Meibum Films Free
PDF
Georgi A. Georgiev; Norihiko Yokoi; Slavyana Ivanova; Rumen Krastev; Zdravko Lalchev
Tags: bacterial artificial chromosomes, blood alcohol concentration, bronchioloalveolar carcinoma, compression, eyedrops
Investigative Ophthalmology & Visual Science July 2012, Vol.53, 4605-4615. doi:10.1167/iovs.12-9907
Differential Expression of Fourteen Proteins between Uveal Melanoma from Patients Who Subsequently Developed Distant Metastases versus Those Who Did Not Free
PDF
Annett Linge; Susan Kennedy; Deirdre O'Flynn; Stephen Beatty; Paul Moriarty; Michael Henry; Martin Clynes; Annemarie Larkin; Paula Meleady
Tags: intraocular melanoma, proteins, fatty acid binding protein 3, neoplasm metastasis, metastasis, distant
Investigative Ophthalmology & Visual Science July 2012, Vol.53, 4634-4643. doi:10.1167/iovs.11-9019
Species Variation in Small Molecule Components of Animal Vitreous Free
PDF
Jenifer Mains; Lay Ean Tan; Tong Zhang; Louise Young; Ruiwen Shi; Clive Wilson
Tags: small molecule, vitreous body, acetylcholinesterase, oryctolagus cuniculus, body tissue
Investigative Ophthalmology & Visual Science July 2012, Vol.53, 4778-4786. doi:10.1167/iovs.12-9998
Pattern of Expression of p53, Its Family Members, and Regulators during Early Ocular Development and in the Post-Mitotic Retina Free
PDF
Linda Vuong; Daniel E. Brobst; Anisse Saadi; Ivana Ivanovic; Muayyad R. Al-Ubaidi
Tags: eye development, family, proteins, retina, polymerase chain reaction
Investigative Ophthalmology & Visual Science July 2012, Vol.53, 4821-4831. doi:10.1167/iovs.11-8681

Clinical and Epidemiologic Research

A New Epidemiological Aid in Deciding Whether to Continue or Stop a Treatment Free
PDF
Mari Elshout; Margriet I. van der Reis; Carroll A. B. Webers; Ellen C. La Heij; Fred Hendrikse; Jan S. A. G. Schouten
Tags: visual acuity, follow-up, intraocular pressure, convergence insufficiency, weight measurement scales
Investigative Ophthalmology & Visual Science July 2012, Vol.53, 4331-4336. doi:10.1167/iovs.11-9242
The Association between Time Spent Outdoors and Myopia Using a Novel Biomarker of Outdoor Light Exposure Free
PDF
Justin C. Sherwin; Alex W. Hewitt; Minas T. Coroneo; Lisa S. Kearns; Lyn R. Griffiths; David A. Mackey
Tags: biological markers, conjunctiva, myopia, autofluorescence, light exposure
Investigative Ophthalmology & Visual Science July 2012, Vol.53, 4363-4370. doi:10.1167/iovs.11-8677
Prevalence and Associated Risk Factors of Myopic Maculopathy in Elderly Chinese: The Shihpai Eye Study Free
PDF
Shih-Jen Chen; Ching-Yu Cheng; An-Fei Li; Kai-Ling Peng; Pesus Chou; Shih-Hwa Chiou; Wen-Ming Hsu
Tags: chinese people, elderly, eye, macular disorders, prevalence
Investigative Ophthalmology & Visual Science July 2012, Vol.53, 4868-4873. doi:10.1167/iovs.12-9919
Topography of Geographic Atrophy in Age-Related Macular Degeneration Free
PDF
Matthias M. Mauschitz; Sofia Fonseca; Petrus Chang; Arno P. Göbel; Monika Fleckenstein; Glenn J. Jaffe; Frank G. Holz; Steffen Schmitz-Valckenberg; for the GAP Study Group
Tags: atrophy, age-related macular degeneration
Investigative Ophthalmology & Visual Science July 2012, Vol.53, 4932-4939. doi:10.1167/iovs.12-9711
The Heritability of Macular Response to Supplemental Lutein and Zeaxanthin: A Classic Twin Study Free
PDF
Christopher J. Hammond; S. H. Melissa Liew; Frederik J. Van Kuijk; Stephen Beatty; John M. Nolan; Tim D. Spector; Clare E. Gilbert
Tags: carotenoids, lutein, twin studies, twins, diet
Investigative Ophthalmology & Visual Science July 2012, Vol.53, 4963-4968. doi:10.1167/iovs.12-9618
Devising Two-Stage and Multistage Phase II Studies on Systemic Adjuvant Therapy for Uveal Melanoma Free
PDF
John Whitehead; Svetlana Tishkovskaya; Jemma O'Connor; Bertil Damato
Tags: adjuvant therapy, intraocular melanoma, phase 2 clinical trials, sample size, research design
Investigative Ophthalmology & Visual Science July 2012, Vol.53, 4986-4989. doi:10.1167/iovs.12-9858
Myopia Control with Orthokeratology Contact Lenses in Spain: Refractive and Biometric Changes Free
PDF
Jacinto Santodomingo-Rubido; César Villa-Collar; Bernard Gilmartin; Ramón Gutiérrez-Ortega
Tags: biometry, myopia, orthokeratology, orthokeratology contact lenses, spain
Investigative Ophthalmology & Visual Science July 2012, Vol.53, 5060-5065. doi:10.1167/iovs.11-8005

Cornea

Anti-Inflammatory Effects of Alpha Linolenic Acid on Human Corneal Epithelial Cells Free
PDF
Nir Erdinest; Or Shmueli; Yoni Grossman; Haim Ovadia; Abraham Solomon
Tags: alpha-linolenic acid, anti-inflammatory agents, corneal epithelial cells, cytokine, interleukin-6
Investigative Ophthalmology & Visual Science July 2012, Vol.53, 4396-4406. doi:10.1167/iovs.12-9724