Select a back issue
Select a back issue
  • Alerts
    User Alerts
    You are adding an alert for:
    Investigative Ophthalmology & Visual Science
    You will receive an email whenever new content is published in the Investigative Ophthalmology & Visual Science. You can manage this and all other alerts in My Account
    The alert will be sent to:
    ×
    This feature is available to authenticated users only.
    Sign In or Create an Account ×

Anatomy and Pathology/Oncology

Epigenetic Regulation Identifies RASEF as a Tumor-Suppressor Gene in Uveal Melanoma Free
PDF
Willem Maat; Sigrid H. W. Beiboer; Martine J. Jager; Gré P. M. Luyten; Nelleke A. Gruis; Pieter A. van der Velden
Tags: genes, uveal melanoma, tumor suppressor genes, methylation, epigenetics
Investigative Ophthalmology & Visual Science April 2008, Vol.49, 1291-1298. doi:https://doi.org/10.1167/iovs.07-1135
Resveratrol Inhibits Uveal Melanoma Tumor Growth via Early Mitochondrial Dysfunction Free
PDF
Paul R. van Ginkel; Soesiawati R. Darjatmoko; Dhruv Sareen; Lalita Subramanian; Saswati Bhattacharya; Mary J. Lindstrom; Daniel M. Albert; Arthur S. Polans
Tags: mitochondria, resveratrol, tumor growth, uveal melanoma, pathophysiology
Investigative Ophthalmology & Visual Science April 2008, Vol.49, 1299-1306. doi:https://doi.org/10.1167/iovs.07-1233

Biochemistry and Molecular Biology

ApoB100,LDLR−/− Mice Exhibit Reduced Electroretinographic Response and Cholesteryl Esters Deposits in the Retina Free
PDF
Lionel Bretillon; Niyazi Acar; Mathias W. Seeliger; Mylène Santos; Marie Annick Maire; Pierre Juanéda; Lucy Martine; Stéphane Grégoire; Corinne Joffre; Alain M. Bron; Catherine Creuzot-Garcher
Tags: cholesterol esters, low density lipoprotein receptor, mice, retina, electroretinography
Investigative Ophthalmology & Visual Science April 2008, Vol.49, 1307-1314. doi:https://doi.org/10.1167/iovs.07-0808
New Type of Mutations in Three Spanish Families with Choroideremia Free
PDF
Maria Garcia-Hoyos; Isabel Lorda-Sanchez; Pilar Gómez-Garre; Cristina Villaverde; Diego Cantalapiedra; Ana Bustamante; Dan Diego-Alvarez; Elena Vallespin; Jesus Gallego-Merlo; Maria Jose Trujillo; Carmen Ramos; Carmen Ayuso
Tags: choroideremia, family, haplotypes, mutation, proteins
Investigative Ophthalmology & Visual Science April 2008, Vol.49, 1315-1321. doi:https://doi.org/10.1167/iovs.07-1169

Clinical and Epidemiologic Research

Does the Level of Physical Activity in University Students Influence Development and Progression of Myopia?—A 2-Year Prospective Cohort Study Free
PDF
Nina Jacobsen; Hanne Jensen; Ernst Goldschmidt
Tags: myopia, physical activity, prospective studies, college students, student
Investigative Ophthalmology & Visual Science April 2008, Vol.49, 1322-1327. doi:https://doi.org/10.1167/iovs.07-1144
Glucose-6-Phosphate Dehydrogenase (G6PD) Deficiency in Nonarteritic Anterior Ischemic Optic Neuropathy in a Sardinian Population, Italy Free
PDF
Antonio Pinna; Giuliana Solinas; Carlo Masia; Angelo Zinellu; Ciriaco Carru; Arturo Carta
Tags: glucosephosphate dehydrogenase, nonarteritic anterior ischemic optic neuropathy, glucose-6-phosphate dehydrogenase deficiency, italy
Investigative Ophthalmology & Visual Science April 2008, Vol.49, 1328-1332. doi:https://doi.org/10.1167/iovs.07-1115
Impact of Glaucoma, Lens Opacities, and Cataract Surgery on Visual Functioning and Related Quality of Life: The Barbados Eye Studies Free
PDF
Suh-Yuh Wu; Anselm Hennis; Barbara Nemesure; M. Cristina Leske
Tags: barbados, cataract, cataract surgery, eye, glaucoma
Investigative Ophthalmology & Visual Science April 2008, Vol.49, 1333-1338. doi:https://doi.org/10.1167/iovs.07-1252
Dominant Genetic Effects on Corneal Astigmatism: The Genes in Myopia (GEM) Twin Study Free
PDF
Mohamed Dirani; Amirul Islam; Sri N. Shekar; Paul N. Baird
Tags: astigmatism, chief complaint, cornea, genes, genetics
Investigative Ophthalmology & Visual Science April 2008, Vol.49, 1339-1344. doi:https://doi.org/10.1167/iovs.07-1011
Associations of Plasma-Soluble Fas Ligand with Aging and Age-Related Macular Degeneration Free
PDF
Shunai Jiang; Siobhan E. Moriarty-Craige; Chun Li; Michael J. Lynn; Jiyang Cai; Dean P. Jones; Paul Sternberg
Tags: age-related macular degeneration, aging, plasma, tumor necrosis factor ligand superfamily member 6
Investigative Ophthalmology & Visual Science April 2008, Vol.49, 1345-1349. doi:https://doi.org/10.1167/iovs.07-0308
Heritability of Optic Disc and Cup Measured by the Heidelberg Retinal Tomography in Chinese: The Guangzhou Twin Eye Study Free
PDF
Mingguang He; Bin Liu; Wenyong Huang; Jian Zhang; Qiuxia Yin; Yingfeng Zheng; Dandan Wang; Jian Ge
Tags: chinese (other dialects), chinese people, eye, optic disk, tomography
Investigative Ophthalmology & Visual Science April 2008, Vol.49, 1350-1355. doi:https://doi.org/10.1167/iovs.07-1146
Heritability of the Iridotrabecular Angle Width Measured by Optical Coherence Tomography in Chinese Children: The Guangzhou Twin Eye Study Free
PDF
Mingguang He; Jian Ge; Dandan Wang; Jian Zhang; Alex W. Hewitt; Yoon-Mi Hur; David A. Mackey; Paul J. Foster
Tags: child, chinese people, eye, optical coherence tomography, twins
Investigative Ophthalmology & Visual Science April 2008, Vol.49, 1356-1361. doi:https://doi.org/10.1167/iovs.07-1397
Ethnic Variability in Retinal Vessel Caliber: A Potential Source of Measurement Error from Ocular Pigmentation?—The Sydney Childhood Eye Study Free
PDF
Elena Rochtchina; Jie Jin Wang; Bronwen Taylor; Tien Y. Wong; Paul Mitchell
Tags: child, eye, measurement error, pigmentation, retinal vascular caliber
Investigative Ophthalmology & Visual Science April 2008, Vol.49, 1362-1366. doi:https://doi.org/10.1167/iovs.07-0150

Cornea

Corneal Wound Healing in an Osteopontin-Deficient Mouse Free
PDF
Ken-ichi Miyazaki; Yuka Okada; Osamu Yamanaka; Ai Kitano; Kazuo Ikeda; Shigeyuki Kon; Toshimitsu Uede; Susan R. Rittling; David T. Denhardt; Winston Whei-Yang Kao; Shizuya Saika
Tags: alkalies, burns, cornea, healing process, mice
Investigative Ophthalmology & Visual Science April 2008, Vol.49, 1367-1375. doi:https://doi.org/10.1167/iovs.07-1007
Characterization of Wound Reepithelialization Using a New Human Tissue-Engineered Corneal Wound Healing Model Free
PDF
Patrick Carrier; Alexandre Deschambeault; Mariève Talbot; Claude J. Giasson; François A. Auger; Sylvain L. Guérin; Lucie Germain
Tags: body tissue, cornea, wound healing, wounds and injuries, epithelium
Investigative Ophthalmology & Visual Science April 2008, Vol.49, 1376-1385. doi:https://doi.org/10.1167/iovs.07-0904
A Murine Model of Dry Eye Induced by an Intelligently Controlled Environmental System Free
PDF
Wei Chen; Xiaobo Zhang; Jingna Zhang; Jinpeng Chen; Shiming Wang; Qinmei Wang; Jia Qu
Tags: cornea, dry eye syndromes, mice, fluorescein stain method, apoptosis
Investigative Ophthalmology & Visual Science April 2008, Vol.49, 1386-1391. doi:https://doi.org/10.1167/iovs.07-0744
Toxic Effects of Recombinant Tissue Plasminogen Activator on Cultured Human Corneal Endothelial Cells Free
PDF
Efdal Yoeruek; Martin S. Spitzer; Olcay Tatar; Tilo Biedermann; Salvatore Grisanti; Matthias Lüke; Karl U. Bartz-Schmidt; Peter Szurman
Tags: alteplase, cornea, endothelial cells, toxic effect
Investigative Ophthalmology & Visual Science April 2008, Vol.49, 1392-1397. doi:https://doi.org/10.1167/iovs.07-1079
The Use of Fractal Analysis and Photometry to Estimate the Accuracy of Bulbar Redness Grading Scales Free
PDF
Marc M. Schulze; Natalie Hutchings; Trefford L. Simpson
Tags: fractals, photometry, weight measurement scales
Investigative Ophthalmology & Visual Science April 2008, Vol.49, 1398-1406. doi:https://doi.org/10.1167/iovs.07-1306
Dry Eye Diagnosis Free
PDF
Santosh Khanal; Alan Tomlinson; Angus McFadyen; Charles Diaper; Kannu Ramaesh
Tags: dry eye syndromes
Investigative Ophthalmology & Visual Science April 2008, Vol.49, 1407-1414. doi:https://doi.org/10.1167/iovs.07-0635
Photorefractive Keratectomy Using Solid State Laser 213 nm and Excimer Laser 193 nm: A Randomized, Contralateral, Comparative, Experimental Study Free
PDF
Nikolaos S. Tsiklis; George D. Kymionis; George A. Kounis; Irini I. Naoumidi; Ioannis G. Pallikaris
Tags: ablation, cornea, excimer lasers, experimental study, lasers
Investigative Ophthalmology & Visual Science April 2008, Vol.49, 1415-1420. doi:https://doi.org/10.1167/iovs.07-1280

Eye Movements, Strabismus, Amblyopia and Neuro-ophthalmology

The Effect of Acute Superior Oblique Palsy on Torsional Optokinetic Nystagmus in Monkeys Free
PDF
Xiaoyan Shan; Jing Tian; Howard S. Ying; Mark F. Walker; David Guyton; Christian Quaia; Lance M. Optican; Rafael J. Tamargo; David S. Zee
Tags: cercopithecidae, eye, fourth cranial nerve palsy, musculoskeletal torsion, function, nystagmus, optokinetic
Investigative Ophthalmology & Visual Science April 2008, Vol.49, 1421-1428. doi:https://doi.org/10.1167/iovs.07-0989

Glaucoma

Induction by Latanoprost of Collagen Gel Contraction Mediated by Human Tenon Fibroblasts: Role of Intracellular Signaling Molecules Free
PDF
Yang Liu; Ji-Ae Ko; Ryoji Yanai; Kazuhiro Kimura; Tai-ichiro Chikama; Takeshi Sagara; Teruo Nishida
Tags: collagen, gel, latanoprost
Investigative Ophthalmology & Visual Science April 2008, Vol.49, 1429-1436. doi:https://doi.org/10.1167/iovs.07-0451
Reduced Retina Microglial Activation and Improved Optic Nerve Integrity with Minocycline Treatment in the DBA/2J Mouse Model of Glaucoma Free
PDF
Alejandra Bosco; Denise M. Inman; Michael R. Steele; Guangming Wu; Ileana Soto; Nicholas Marsh-Armstrong; Walter C. Hubbard; David J. Calkins; Philip J. Horner; Monica L. Vetter
Tags: glaucoma, mice, minocycline, retina, optic nerve
Investigative Ophthalmology & Visual Science April 2008, Vol.49, 1437-1446. doi:https://doi.org/10.1167/iovs.07-1337
Mitochondrial Complex I Defect Induces ROS Release and Degeneration in Trabecular Meshwork Cells of POAG Patients: Protection by Antioxidants Free
PDF
Yuan He; Kar Wah Leung; Yue-Hong Zhang; Shan Duan; Xiu-Feng Zhong; Ru-Zhang Jiang; Zhan Peng; Joyce Tombran-Tink; Jian Ge
Tags: antioxidants, cytochrome c, mitochondria, open-angle glaucoma, tissue degeneration
Investigative Ophthalmology & Visual Science April 2008, Vol.49, 1447-1458. doi:https://doi.org/10.1167/iovs.07-1361
Association of LOXL1 Common Sequence Variants in German and Italian Patients with Pseudoexfoliation Syndrome and Pseudoexfoliation Glaucoma Free
PDF
Francesca Pasutto; Mandy Krumbiegel; Christian Y. Mardin; Daniela Paoli; Robert Lämmer; Bernhard H. F. Weber; Friedrich E. Kruse; Ursula Schlötzer-Schrehardt; André Reis
Tags: exfoliation syndrome, german, italian, single nucleotide polymorphism
Investigative Ophthalmology & Visual Science April 2008, Vol.49, 1459-1463. doi:https://doi.org/10.1167/iovs.07-1449
The Effect of TGF-β2 on Elastin, Type VI Collagen, and Components of the Proteolytic Degradation System in Human Optic Nerve Astrocytes Free
PDF
Carolin Neumann; Alice Yu; Ulrich Welge-Lüssen; Elke Lütjen-Drecoll; Marco Birke
Tags: astrocytes, collagen type vi, elastin, optic nerve, catabolism
Investigative Ophthalmology & Visual Science April 2008, Vol.49, 1464-1472. doi:https://doi.org/10.1167/iovs.07-1053
Circadian Variation of Aqueous Dynamics in Young Healthy Adults Free
PDF
Arthur J. Sit; Cherie B. Nau; Jay W. McLaren; Douglas H. Johnson; David Hodge
Tags: adult, fluid flow, intraocular pressure, night time, unit of flow rate
Investigative Ophthalmology & Visual Science April 2008, Vol.49, 1473-1479. doi:https://doi.org/10.1167/iovs.07-1139

Immunology and Microbiology

Toward Improving Therapeutic Regimens for Bacillus Endophthalmitis Free
PDF
Brandt J. Wiskur; Michael L. Robinson; Allison J. Farrand; Billy D. Novosad; Michelle C. Callegan
Tags: antibiotics, bacillus, dexamethasone, endophthalmitis, eye
Investigative Ophthalmology & Visual Science April 2008, Vol.49, 1480-1487. doi:https://doi.org/10.1167/iovs.07-1303
Activated Inflammatory Infiltrate in HSV-1-Infected Corneas without Herpes Stromal Keratitis Free
PDF
Sherrie J. Divito; Robert L. Hendricks
Tags: cornea, infiltrates, stromal keratitis, simplexvirus
Investigative Ophthalmology & Visual Science April 2008, Vol.49, 1488-1495. doi:https://doi.org/10.1167/iovs.07-1107
Effects of λ-Carrageenan on In Vitro Replication of Feline Herpesvirus and on Experimentally Induced Herpetic Conjunctivitis in Cats Free
PDF
Jean Stiles; Lynn Guptill-Yoran; George E. Moore; Roman M. Pogranichniy
Tags: carrageenan, cats, herpes simplex conjunctivitis, simplexvirus, herpesviridae
Investigative Ophthalmology & Visual Science April 2008, Vol.49, 1496-1501. doi:https://doi.org/10.1167/iovs.07-1245
Substance P Promotes Susceptibility to Pseudomonas aeruginosa Keratitis in Resistant Mice: Anti-inflammatory Mediators Downregulated Free
PDF
Sharon A. McClellan; Yunfan Zhang; Ronald P. Barrett; Linda D. Hazlett
Tags: antagonists, anti-inflammatory agents, cornea, disease susceptibility, enzyme-linked immunosorbent assay
Investigative Ophthalmology & Visual Science April 2008, Vol.49, 1502-1511. doi:https://doi.org/10.1167/iovs.07-1369
Experimental Induction and Three-Dimensional Two-Photon Imaging of Conjunctiva-Associated Lymphoid Tissue Free
PDF
Philipp Steven; Jan Rupp; Gereon Hüttmann; Norbert Koop; Carmen Lensing; Horst Laqua; Andreas Gebert
Tags: conjunctiva, diagnostic imaging, lymphoid tissue, photons, mice
Investigative Ophthalmology & Visual Science April 2008, Vol.49, 1512-1517. doi:https://doi.org/10.1167/iovs.07-0809
NOD2, the Gene Responsible for Familial Granulomatous Uveitis, in a Mouse Model of Uveitis Free
PDF
Holly L. Rosenzweig; Tammy M. Martin; Monica M. Jann; Stephen R. Planck; Michael P. Davey; Koichi Kobayashi; Richard A. Flavell; James T. Rosenbaum
Tags: granulomatous uveitis, mice, uveitis, genes, eye inflammation
Investigative Ophthalmology & Visual Science April 2008, Vol.49, 1518-1524. doi:https://doi.org/10.1167/iovs.07-1174

Lens

Mutation in a Novel Connexin-like Gene (Gjf1) in the Mouse Affects Early Lens Development and Causes a Variable Small-Eye Phenotype Free
PDF
Oliver Puk; Jana Löster; Claudia Dalke; Dian Soewarto; Helmut Fuchs; Birgit Budde; Peter Nürnberg; Eckhard Wolf; Martin Hrabé de Angelis; Jochen Graw
Tags: eye, gap junction protein, genes, lens (device), lens, crystalline
Investigative Ophthalmology & Visual Science April 2008, Vol.49, 1525-1532. doi:https://doi.org/10.1167/iovs.07-1033
Novel Allele of Crybb2 in the Mouse and Its Expression in the Brain Free
PDF
Koustav Ganguly; Jack Favor; Angelika Neuhäuser-Klaus; Rodica Sandulache; Oliver Puk; Johannes Beckers; Marion Horsch; Sandra Schädler; Daniela Vogt Weisenhorn; Wolfgang Wurst; Jochen Graw
Tags: alleles, brain, mice, proteins, crystallins
Investigative Ophthalmology & Visual Science April 2008, Vol.49, 1533-1541. doi:https://doi.org/10.1167/iovs.07-0788
Dual Roles for Prox1 in the Regulation of the Chicken βB1-Crystallin Promoter Free
PDF
Xiaoren Chen; Jennifer R. Taube; Vladimir I. Simirskii; Tapan P. Patel; Melinda K. Duncan
Tags: chickens, crystallins, lens (device), lens, crystalline, dna
Investigative Ophthalmology & Visual Science April 2008, Vol.49, 1542-1552. doi:https://doi.org/10.1167/iovs.07-1300
Posttranslational Modifications in Lens Fiber Connexins Identified by Off-Line-HPLC MALDI-Quadrupole Time-of-Flight Mass Spectrometry Free
PDF
David Shearer; Werner Ens; Ken Standing; Gunnar Valdimarsson
Tags: gap junction protein, high pressure liquid chromatography procedure, lens (device), lens, crystalline, peptides
Investigative Ophthalmology & Visual Science April 2008, Vol.49, 1553-1562. doi:https://doi.org/10.1167/iovs.07-1193

Physiology and Pharmacology

Bestrophin-2 Is Involved in the Generation of Intraocular Pressure Free
PDF
Benjamin Bakall; Precious McLaughlin; J. Brett Stanton; Youwen Zhang; H. Criss Hartzell; Lihua Y. Marmorstein; Alan D. Marmorstein
Tags: genes, intraocular pressure, mice, eye, proteins
Investigative Ophthalmology & Visual Science April 2008, Vol.49, 1563-1570. doi:https://doi.org/10.1167/iovs.07-1338

Retina

Characterization of Outer Retinal Morphology with High-Speed, Ultrahigh-Resolution Optical Coherence Tomography Free
PDF
Vivek J. Srinivasan; Bryan K. Monson; Maciej Wojtkowski; Richard A. Bilonick; Iwona Gorczynska; Royce Chen; Jay S. Duker; Joel S. Schuman; James G. Fujimoto
Tags: language morphology, morphology, optical coherence tomography, retina, diagnostic imaging
Investigative Ophthalmology & Visual Science April 2008, Vol.49, 1571-1579. doi:https://doi.org/10.1167/iovs.07-0838
Retinal Laminar Architecture in Human Retinitis Pigmentosa Caused by Rhodopsin Gene Mutations Free
PDF
Tomas S. Aleman; Artur V. Cideciyan; Alexander Sumaroka; Elizabeth A. M. Windsor; Waldo Herrera; D. Alan White; Shalesh Kaushal; Anjani Naidu; Alejandro J. Roman; Sharon B. Schwartz; Edwin M. Stone; Samuel G. Jacobson
Tags: mutation, retina, retinal cone, retinitis pigmentosa, rhodopsin
Investigative Ophthalmology & Visual Science April 2008, Vol.49, 1580-1590. doi:https://doi.org/10.1167/iovs.07-1110
Activated NAD(P)H Oxidase from Supplemental Oxygen Induces Neovascularization Independent of VEGF in Retinopathy of Prematurity Model Free
PDF
Yuta Saito; Abhineet Uppal; Grace Byfield; Steven Budd; M. Elizabeth Hartnett
Tags: oxidase, oxygen, vascular endothelial growth factor a, retina, retinopathy of prematurity
Investigative Ophthalmology & Visual Science April 2008, Vol.49, 1591-1598. doi:https://doi.org/10.1167/iovs.07-1356
Retinal Microglia and Uveal Tract Dendritic Cells and Macrophages Are Not CX3CR1 Dependent in Their Recruitment and Distribution in the Young Mouse Eye Free
PDF
Jelena Kezic; Heping Xu; Holly R. Chinnery; Connor C. Murphy; Paul G. McMenamin
Tags: eye, macrophages, mice, microglia, uvea
Investigative Ophthalmology & Visual Science April 2008, Vol.49, 1599-1608. doi:https://doi.org/10.1167/iovs.07-0953
Impact of Optic Media Opacities and Image Compression on Quantitative Analysis of Optical Coherence Tomography Free
PDF
Christoph Tappeiner; Daniel Barthelmes; Mathias H. Abegg; Sebastian Wolf; Johannes C. Fleischhauer
Tags: eye, filters, image compression, optical coherence tomography, optics
Investigative Ophthalmology & Visual Science April 2008, Vol.49, 1609-1614. doi:https://doi.org/10.1167/iovs.07-1264
Circadian Regulation of Retinoschisin in the Chick Retina Free
PDF
Michael L. Ko; Yilin Liu; Liheng Shi; Dorothy Trump; Gladys Y.-P. Ko
Tags: proteins, regulation, retina, bodily secretions
Investigative Ophthalmology & Visual Science April 2008, Vol.49, 1615-1621. doi:https://doi.org/10.1167/iovs.07-1189
Local Diabetic Retinopathy Prediction by Multifocal ERG Delays over 3 Years Free
PDF
Jason S. Ng; Marcus A. Bearse, Jr; Marilyn E. Schneck; Shirin Barez; Anthony J. Adams
Tags: diabetes mellitus, diabetic retinopathy, electroretinography, retinal diseases, recurrence
Investigative Ophthalmology & Visual Science April 2008, Vol.49, 1622-1628. doi:https://doi.org/10.1167/iovs.07-1157
Threshold Amplitude and Frequency for Ocular Tissue Release from a Vibrating Instrument: An Experimental Study Free
PDF
Kristel Maaijwee; Twan Koolen; Dagmar Rosenbrand; Elmer Jacobs; Sander Kleinheerenbrink; Arjan Knulst; Joop Bos; Wim P. Holland; Alex Brouwer; Jan C. van Meurs; Sander Schutte
Tags: body tissue, tissue transplants, vibration, experimental study, friction
Investigative Ophthalmology & Visual Science April 2008, Vol.49, 1629-1632. doi:https://doi.org/10.1167/iovs.07-1220
Evaluation of the New Photosensitizer Stakel (WST-11) for Photodynamic Choroidal Vessel Occlusion in Rabbit and Rat Eyes Free
PDF
Marianne Berdugo; Riad A. Bejjani; Fatemeh Valamanesh; Michele Savoldelli; Jean-Claude Jeanny; Dominique Blanc; Herve Ficheux; Avigdor Scherz; Yoram Salomon; David BenEzra; Francine Behar-Cohen
Tags: choroidal neovascularization, eye, lasers, oryctolagus cuniculus, photosensitizing agents
Investigative Ophthalmology & Visual Science April 2008, Vol.49, 1633-1644. doi:https://doi.org/10.1167/iovs.07-0767
Beneficial Effect of Zeaxanthin on Retinal Metabolic Abnormalities in Diabetic Rats Free
PDF
Renu A. Kowluru; Bindu Menon; Dennis L. Gierhart
Tags: diabetes mellitus, rats, retina
Investigative Ophthalmology & Visual Science April 2008, Vol.49, 1645-1651. doi:https://doi.org/10.1167/iovs.07-0764
Toll-like Receptor Polymorphisms and Age-Related Macular Degeneration Free
PDF
Albert O. Edwards; Dequan Chen; Brooke L. Fridley; Katherine M. James; Yanhong Wu; Goncalo Abecasis; Anand Swaroop; Mohammad Othman; Kari Branham; Sudha K. Iyengar; Theru A. Sivakumaran; Ronald Klein; Barbara E. K. Klein; Nirubol Tosakulwong
Tags: age-related macular degeneration, cohort studies, genes, genotype, genotype determination
Investigative Ophthalmology & Visual Science April 2008, Vol.49, 1652-1659. doi:https://doi.org/10.1167/iovs.07-1378
Carnitine Palmitoyltransferase I and Acyl-CoA Dehydrogenase 9 in Retina: Insights of Retinopathy in Mitochondrial Trifunctional Protein Defects Free
PDF
Eva Roomets; Tero Kivelä; Tiina Tyni
Tags: acyl coenzyme a, carnitine o-palmitoyltransferase, mitochondria, oxidoreductase, proteins
Investigative Ophthalmology & Visual Science April 2008, Vol.49, 1660-1664. doi:https://doi.org/10.1167/iovs.07-1094

Retinal Cell Biology

Modulation of Nrf2-Dependent Antioxidant Functions in the RPE by Zip2, a Zinc Transporter Protein Free
PDF
Kasra A. Rezaei; Yan Chen; Jiyang Cai; Paul Sternberg
Tags: antioxidants, zinc, zinc transporter, mass or substance concentration per volume, genes
Investigative Ophthalmology & Visual Science April 2008, Vol.49, 1665-1670. doi:https://doi.org/10.1167/iovs.07-0959
Essential Roles of the PI3 Kinase/Akt Pathway in Regulating Nrf2-Dependent Antioxidant Functions in the RPE Free
PDF
Ling Wang; Yan Chen; Paul Sternberg; Jiyang Cai
Tags: 1-phosphatidylinositol 3-kinase, akt signaling pathway, antioxidants, proto-oncogene proteins c-akt, sulforaphane
Investigative Ophthalmology & Visual Science April 2008, Vol.49, 1671-1678. doi:https://doi.org/10.1167/iovs.07-1099
Inhibition of Choroidal Neovascularization with an Anti-Inflammatory Carotenoid Astaxanthin Free
PDF
Kanako Izumi-Nagai; Norihiro Nagai; Kazuhiro Ohgami; Shingo Satofuka; Yoko Ozawa; Kazuo Tsubota; Shigeaki Ohno; Yuichi Oike; Susumu Ishida
Tags: carotenoids, choroidal neovascularization, anti-inflammatory agents, macrophages
Investigative Ophthalmology & Visual Science April 2008, Vol.49, 1679-1685. doi:https://doi.org/10.1167/iovs.07-1426
Elevated MMP Expression in the MRL Mouse Retina Creates a Permissive Environment for Retinal Regeneration Free
PDF
Budd Tucker; Henry Klassen; Liu Yang; Dong Feng Chen; Michael J. Young
Tags: mice, retina, cd44 antigens, homing-associated cell adhesion molecule, gelatinase a
Investigative Ophthalmology & Visual Science April 2008, Vol.49, 1686-1695. doi:https://doi.org/10.1167/iovs.07-1058
FGF19 Exhibits Neuroprotective Effects on Adult Mammalian Photoreceptors In Vitro Free
PDF
Sandrine Siffroi-Fernandez; Marie-Paule Felder-Schmittbuhl; Hemant Khanna; Anand Swaroop; David Hicks
Tags: adult, antibodies, fibroblast growth factor receptors, mammals, neuroprotective effect
Investigative Ophthalmology & Visual Science April 2008, Vol.49, 1696-1704. doi:https://doi.org/10.1167/iovs.07-1272
Mecamylamine Suppresses Basal and Nicotine-Stimulated Choroidal Neovascularization Free
PDF
Katsuji Kiuchi; Masato Matsuoka; Jenny C. Wu; Raquel Lima e Silva; Muralitharan Kengatharan; Mary Verghese; Shinji Ueno; Katsutoshi Yokoi; Naw Htee Khu; John P. Cooke; Peter A. Campochiaro
Tags: choroidal neovascularization, mecamylamine, nicotine, endothelial cells
Investigative Ophthalmology & Visual Science April 2008, Vol.49, 1705-1711. doi:https://doi.org/10.1167/iovs.07-0089
The Protective Effect of Quercetin against Oxidative Stress in the Human RPE In Vitro Free
PDF
Daniel Kook; Armin H. Wolf; Alice L. Yu; Aljoscha S. Neubauer; Siegfried G. Priglinger; Anselm Kampik; Ulrich C. Welge-Lüssen
Tags: oxidative stress, quercetin, retinal pigment cell, caveolins
Investigative Ophthalmology & Visual Science April 2008, Vol.49, 1712-1720. doi:https://doi.org/10.1167/iovs.07-0477
Characterization of a Bcl-XL-Interacting Protein FKBP8 and Its Splice Variant in Human RPE Cells Free
PDF
Yan Chen; Paul Sternberg; Jiyang Cai
Tags: proteins, retinal pigment cell, thapsigargin, tacrolimus, apoptosis
Investigative Ophthalmology & Visual Science April 2008, Vol.49, 1721-1727. doi:https://doi.org/10.1167/iovs.07-1121

Visual Neuroscience

An fMRI Study of Saccadic and Smooth-Pursuit Eye Movement Control in Patients with Age-Related Macular Degeneration Free
PDF
Deborah M. Little; Keith R. Thulborn; Janet P. Szlyk
Tags: age-related macular degeneration, diagnostic imaging, eye movement, functional magnetic resonance imaging, primary visual cortex
Investigative Ophthalmology & Visual Science April 2008, Vol.49, 1728-1735. doi:https://doi.org/10.1167/iovs.07-0372

Visual Psychophysics and Physiological Optics

Accommodation-Related Changes in Monochromatic Aberrations of the Human Eye as a Function of Age Free
PDF
Norberto López-Gil; Vicente Fernández-Sánchez; Richard Legras; Robert Montés-Micó; Francisco Lara; Jean Luc Nguyen-Khoa
Tags: eye, visual accommodation, pupil
Investigative Ophthalmology & Visual Science April 2008, Vol.49, 1736-1743. doi:https://doi.org/10.1167/iovs.06-0802

Erratum

ERRATUM Free
PDF
Investigative Ophthalmology & Visual Science April 2008, Vol.49, 1298. doi:
Copyright © 2025 Association for Research in Vision and Ophthalmology.
×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×
This site uses cookies. By continuing to use our website, you are agreeing to our privacy policy.Accept