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Anatomy and Pathology/Oncology

Effects of Form Deprivation on Peripheral Refractions and Ocular Shape in Infant Rhesus Monkeys (Macaca mulatta) Free
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Juan Huang; Li-Fang Hung; Ramkumar Ramamirtham; Terry L. Blasdel; Tammy L. Humbird; Kurt H. Bockhorst; Earl L. Smith, III
Tags: cercopithecidae, eye, hyperopia, infant, macaca mulatta
Investigative Ophthalmology & Visual Science September 2009, Vol.50, 4033-4044. doi:https://doi.org/10.1167/iovs.08-3162
Effects of Elevated Pax6 Expression and Genetic Background on Mouse Eye Development Free
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Simon A. Chanas; J. Martin Collinson; Thaya Ramaesh; Natalie Dorà; Dirk A. Kleinjan; Robert E. Hill; John D. West
Tags: body tissue, chimera organism, eye, fetus, genetics
Investigative Ophthalmology & Visual Science September 2009, Vol.50, 4045-4059. doi:https://doi.org/10.1167/iovs.07-1630
Exfoliative Epitheliopathy of Bullous Keratopathy with Breaches in the MUC16 Glyocalyx Free
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Ben J. Glasgow; Oktay K. Gasymov; Richard C. Casey
Tags: bullous keratopathy, epithelium
Investigative Ophthalmology & Visual Science September 2009, Vol.50, 4060-4064. doi:https://doi.org/10.1167/iovs.08-3361

Biochemistry and Molecular Biology

Genetic Analysis of Indian Families with Autosomal Recessive Retinitis Pigmentosa by Homozygosity Screening Free
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Hardeep Pal Singh; Subhadra Jalali; Raja Narayanan; Chitra Kannabiran
Tags: autosomal recessive inheritance, family, genes, genetic analysis, homozygote
Investigative Ophthalmology & Visual Science September 2009, Vol.50, 4065-4071. doi:https://doi.org/10.1167/iovs.09-3479
Molecular Sequelae of Histone Deacetylase Inhibition in Human Retinoblastoma Cell Lines: Clinical Implications Free
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Vassiliki Poulaki; Constantine S. Mitsiades; Vassiliki Kotoula; Joseph Negri; Ciaran McMullan; Joan W. Miller; Paul A. Marks; Nicholas Mitsiades
Tags: retinoblastoma, vorinostat, apoptosis, cell lines, caspases
Investigative Ophthalmology & Visual Science September 2009, Vol.50, 4072-4079. doi:https://doi.org/10.1167/iovs.09-3517

Clinical and Epidemiologic Research

COL1A1 and COL2A1 Genes and Myopia Susceptibility: Evidence of Association and Suggestive Linkage to the COL2A1 Locus Free
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Ravikanth Metlapally; Yi-Ju Li; Khanh-Nhat Tran-Viet; Diana Abbott; Gregory R. Czaja; Francois Malecaze; Patrick Calvas; David Mackey; Thomas Rosenberg; Sandrine Paget; Tetyana Zayats; Michael J. Owen; Jeremy A. Guggenheim; Terri L. Young
Tags: disease susceptibility, genes, myopia
Investigative Ophthalmology & Visual Science September 2009, Vol.50, 4080-4086. doi:https://doi.org/10.1167/iovs.08-3346
Heritability of Central Corneal Thickness in Nuclear Families Free
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John A. Landers; Alex W. Hewitt; David P. Dimasi; Jac C. Charlesworth; Tania Straga; Richard A. D. Mills; Ravi Savarirayan; David A. Mackey; Kathryn P. Burdon; Jamie E. Craig
Tags: cornea, nuclear family, offspring, child, parent
Investigative Ophthalmology & Visual Science September 2009, Vol.50, 4087-4090. doi:https://doi.org/10.1167/iovs.08-3271
Relationship of Retinal Vascular Caliber with Retinal Nerve Fiber Layer Thickness: The Singapore Malay Eye Study Free
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Yingfeng Zheng; Ning Cheung; Tin Aung; Paul Mitchell; Mingguang He; Tien Y. Wong
Tags: eye, retinal nerve fiber layer, retinal vascular caliber, singapore, glaucoma
Investigative Ophthalmology & Visual Science September 2009, Vol.50, 4091-4096. doi:https://doi.org/10.1167/iovs.09-3444
The Relationship of Intraocular Pressure with Age, Systolic Blood Pressure, and Central Corneal Thickness in an Asian Population Free
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Tina T. Wong; Tien Y. Wong; Paul J. Foster; Jonathan G. Crowston; Chee-Weng Fong; Tin Aung
Tags: asian, cornea, intraocular pressure, systolic blood pressure
Investigative Ophthalmology & Visual Science September 2009, Vol.50, 4097-4102. doi:https://doi.org/10.1167/iovs.08-2822
Impact of the Severity of Distance and Near-Vision Impairment on Depression and Vision-Specific Quality of Life in Older People Living in Residential Care Free
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Ecosse L. Lamoureux; Eva Fenwick; Kirsten Moore; Marlena Klaic; Karen Borschmann; Keith Hill
Tags: depressive disorders, myopia, quality of life, vision, older adult
Investigative Ophthalmology & Visual Science September 2009, Vol.50, 4103-4109. doi:https://doi.org/10.1167/iovs.08-3294
Is Routine Pupil Dilation Safe among Asian Patients with Diabetes? Free
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Gavin S. Tan; Ching-Yee Wong; Tien Yin Wong; Chitra V. Govindasamy; Edmund Y. Wong; Ian Y. Yeo; Tin Aung
Tags: asian, diabetes mellitus, intraocular pressure, mydriasis, pupil dilation
Investigative Ophthalmology & Visual Science September 2009, Vol.50, 4110-4113. doi:https://doi.org/10.1167/iovs.08-2745
Causes of Blindness and Visual Impairment in Nigeria: The Nigeria National Blindness and Visual Impairment Survey Free
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Mohammed M. Abdull; Selvaraj Sivasubramaniam; Gudlavalleti V. S. Murthy; Clare Gilbert; Tafida Abubakar; Christian Ezelum; Mansur M. Rabiu
Tags: blindness, nigeria, visual impairment, surveys, eye
Investigative Ophthalmology & Visual Science September 2009, Vol.50, 4114-4120. doi:https://doi.org/10.1167/iovs.09-3507

Cornea

Evidence for a Relative Thinning of the Peripheral Cornea with Age in White European Subjects Free
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Sven Jonuscheit; Michael J. Doughty
Tags: cornea
Investigative Ophthalmology & Visual Science September 2009, Vol.50, 4121-4128. doi:https://doi.org/10.1167/iovs.08-3298
Decreased Corneal Sensitivity and Tear Production in Fibromyalgia Free
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Juana Gallar; Celia Morales; Vanesa Freire; M. Carmen Acosta; Carlos Belmonte; Juan A. Duran
Tags: cornea, fibromyalgia, tear production
Investigative Ophthalmology & Visual Science September 2009, Vol.50, 4129-4134. doi:https://doi.org/10.1167/iovs.08-3083
Reliability of Noncontact Pachymetry after Laser In Situ Keratomileusis Free
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Miguel J. Maldonado; Alberto López-Miguel; Juan C. Nieto; Juan Cano-Parra; Begoña Calvo; Jorge L. Alió
Tags: keratomileusis, laser in situ, optical pachymetry, reliability, cornea, eye
Investigative Ophthalmology & Visual Science September 2009, Vol.50, 4135-4141. doi:https://doi.org/10.1167/iovs.09-3408
Mutational Spectrum of SLC4A11 in Autosomal Recessive CHED in Saudi Arabia Free
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Mohammed A. Aldahmesh; Arif O. Khan; Brian F. Meyer; Fowzan S. Alkuraya
Tags: autosomal recessive inheritance, mutation, saudi arabia, dna, proteins
Investigative Ophthalmology & Visual Science September 2009, Vol.50, 4142-4145. doi:https://doi.org/10.1167/iovs.08-3006
Minor Influence of Myopic Laser In Situ Keratomileusis on the Posterior Corneal Surface Free
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Alfonso Pérez-Escudero; Carlos Dorronsoro; Lucie Sawides; Laura Remón; Jesús Merayo-Lloves; Susana Marcos
Tags: cornea, eye, keratomileusis, laser in situ, surgical procedures, operative
Investigative Ophthalmology & Visual Science September 2009, Vol.50, 4146-4154. doi:https://doi.org/10.1167/iovs.09-3411
Stromal Edema in Klf4 Conditional Null Mouse Cornea Is Associated with Altered Collagen Fibril Organization and Reduced Proteoglycans Free
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Robert D. Young; Shivalingappa K. Swamynathan; Craig Boote; Mary Mann; Andrew J. Quantock; Joram Piatigorsky; James L. Funderburgh; Keith M. Meek
Tags: collagen, cornea, edema, fibril, proteoglycan
Investigative Ophthalmology & Visual Science September 2009, Vol.50, 4155-4161. doi:https://doi.org/10.1167/iovs.09-3561
Molecular Profiling of Conjunctival Epithelial Side-Population Stem Cells: Atypical Cell Surface Markers and Sources of a Slow-Cycling Phenotype Free
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M. A. Murat Akinci; Helen Turner; Maria Taveras; Alex Barash; Zheng Wang; Peter Reinach; J. Mario Wolosin
Tags: atypical, body tissue, conjunctiva, epithelium, gene expression
Investigative Ophthalmology & Visual Science September 2009, Vol.50, 4162-4172. doi:https://doi.org/10.1167/iovs.08-2861
Embryonic Corneal Schwann Cells Express Some Schwann Cell Marker mRNAs, but No Mature Schwann Cell Marker Proteins Free
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Abigail H. Conrad; Michael Albrecht; Maya Pettit-Scott; Gary W. Conrad
Tags: cornea, embryo, neurons, proteins, spinal cord stimulation
Investigative Ophthalmology & Visual Science September 2009, Vol.50, 4173-4184. doi:https://doi.org/10.1167/iovs.08-3136
A Novel Antimicrobial Peptidoglycan Recognition Protein in the Cornea Free
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Amit Ghosh; Seakwoo Lee; Roman Dziarski; Shukti Chakravarti
Tags: antimicrobials, cornea, mice, peptidoglycan, proteins
Investigative Ophthalmology & Visual Science September 2009, Vol.50, 4185-4191. doi:https://doi.org/10.1167/iovs.08-3040
The Role of Bowman’s Layer in Corneal Regeneration after Phototherapeutic Keratectomy: A Prospective Study Using In Vivo Confocal Microscopy Free
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Neil Lagali; Johan Germundsson; Per Fagerholm
Tags: bowman's layer, cornea, microscopy, confocal, prospective studies, neurons
Investigative Ophthalmology & Visual Science September 2009, Vol.50, 4192-4198. doi:https://doi.org/10.1167/iovs.09-3781

Eye Movements, Strabismus, Amblyopia and Neuro-ophthalmology

The Effects of Optic Disc Drusen on the Latency of the Pattern-Reversal Checkerboard and Multifocal Visual Evoked Potentials Free
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Tomas M. Grippo; Isaac Ezon; Fabio N. Kanadani; Boonchai Wangsupadilok; Celso Tello; Jeffrey M. Liebmann; Robert Ritch; Donald C. Hood
Tags: evoked potentials, visual, eye, optic disk drusen
Investigative Ophthalmology & Visual Science September 2009, Vol.50, 4199-4204. doi:https://doi.org/10.1167/iovs.08-2887
Efficiency and Safety of AAV-Mediated Gene Delivery of the Human ND4 Complex I Subunit in the Mouse Visual System Free
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John Guy; Xiaoping Qi; Rajeshwari D. Koilkonda; Tania Arguello; Tsung-Han Chou; Marco Ruggeri; Vittorio Porciatti; Alfred S. Lewin; William W. Hauswirth
Tags: eye, genes, mice, safety, visual system
Investigative Ophthalmology & Visual Science September 2009, Vol.50, 4205-4214. doi:https://doi.org/10.1167/iovs.08-3214
The Influence of First Near-Spectacle Reading Correction on Accommodation and Its Interaction with Convergence Free
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Indu Vedamurthy; Wendy W. Harrison; Yue Liu; Ian Cox; Clifton M. Schor
Tags: reading (activity), visual accommodation, eyeglasses
Investigative Ophthalmology & Visual Science September 2009, Vol.50, 4215-4222. doi:https://doi.org/10.1167/iovs.08-3021

Glaucoma

Retrobulbar Optic Nerve Diameter Measured by High-Speed Magnetic Resonance Imaging as a Biomarker for Axonal Loss in Glaucomatous Optic Atrophy Free
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Wolf A. Lagrèze; Mirjam Gaggl; Matthias Weigel; Jürgen Schulte-Mönting; Anima Bühler; Michael Bach; Robin D. Munk; Thorsten A. Bley
Tags: biological markers, diameter, glaucomatous optic disc cupping, magnetic resonance imaging, optic nerve
Investigative Ophthalmology & Visual Science September 2009, Vol.50, 4223-4228. doi:https://doi.org/10.1167/iovs.08-2683
The Relationship between Diurnal Variations in Intraocular Pressure Measurements and Central Corneal Thickness and Corneal Hysteresis Free
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Aachal Kotecha; David P. Crabb; Alexander Spratt; David F. Garway-Heath
Tags: cornea, corneal hysteresis, intraocular pressure, circadian rhythms
Investigative Ophthalmology & Visual Science September 2009, Vol.50, 4229-4236. doi:https://doi.org/10.1167/iovs.08-2955
Analysis of α2-adrenergic Receptors and Effect of Brimonidine on Matrix Metalloproteinases and Their Inhibitors in Human Ciliary Body Free
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Yen Hoong Ooi; Dong-Jin Oh; Douglas J. Rhee
Tags: brimonidine, ciliary body, matrix metalloproteinases, tissue inhibitor of metalloproteinases, body tissue
Investigative Ophthalmology & Visual Science September 2009, Vol.50, 4237-4243. doi:https://doi.org/10.1167/iovs.08-2312
Transplanted Oligodendrocyte Precursor Cells Reduce Neurodegeneration in a Model of Glaucoma Free
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Natalie D. Bull; Karen-Amanda Irvine; Robin J. M. Franklin; Keith R. Martin
Tags: glaucoma, transplantation, oligodendroglia, nerve degeneration
Investigative Ophthalmology & Visual Science September 2009, Vol.50, 4244-4253. doi:https://doi.org/10.1167/iovs.08-3239
A Test of a Linear Model of Glaucomatous Structure–Function Loss Reveals Sources of Variability in Retinal Nerve Fiber and Visual Field Measurements Free
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Donald C. Hood; Susan C. Anderson; Michael Wall; Ali S. Raza; Randy H. Kardon
Tags: glaucoma, nerve fibers, retinal nerve fiber layer, visual fields
Investigative Ophthalmology & Visual Science September 2009, Vol.50, 4254-4266. doi:https://doi.org/10.1167/iovs.08-2697
Recharacterization of the RGC-5 Retinal Ganglion Cell Line Free
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Nicole J. Van Bergen; John P. M. Wood; Glyn Chidlow; Ian A. Trounce; Robert J. Casson; Won-Kyu Ju; Robert N. Weinreb; Jonathan G. Crowston
Tags: cell lines, concanavalin a, dna, glutamate, glutamates
Investigative Ophthalmology & Visual Science September 2009, Vol.50, 4267-4272. doi:https://doi.org/10.1167/iovs.09-3484

Immunology and Microbiology

Steroid Refractory CD4+ T Cells in Patients with Sight-Threatening Uveitis Free
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Richard W. J. Lee; Lauren P. Schewitz; Lindsay B. Nicholson; Colin M. Dayan; Andrew D. Dick
Tags: steroids, t-lymphocytes, uveitis, vision, aldesleukin
Investigative Ophthalmology & Visual Science September 2009, Vol.50, 4273-4278. doi:https://doi.org/10.1167/iovs.08-3152
rAAV.sFlt-1 Gene Therapy Achieves Lasting Reversal of Retinal Neovascularization in the Absence of a Strong Immune Response to the Viral Vector Free
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Chooi-May Lai; Marie J. Estcourt; Matthew Wikstrom; Robyn P. Himbeck; Nigel L. Barnett; Meliha Brankov; Lisa B. G. Tee; Sarah A. Dunlop; Mariapia A. Degli-Esposti; Elizabeth P. Rakoczy
Tags: eye, gene therapy, immune response, mice, retinal neovascularization
Investigative Ophthalmology & Visual Science September 2009, Vol.50, 4279-4287. doi:https://doi.org/10.1167/iovs.08-3253
Development of Experimental Autoimmune Uveitis: Efficient Recruitment of Monocytes Is Independent of CCR2 Free
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Athanasios Dagkalis; Carol Wallace; Heping Xu; Sebastian Liebau; Ayyakkannu Manivannan; Michael A. Stone; Matthias Mack; Janet Liversidge; Isabel J. Crane
Tags: autoimmune diseases, mice, monocyte chemoattractant protein-1, monocytes, retina
Investigative Ophthalmology & Visual Science September 2009, Vol.50, 4288-4294. doi:https://doi.org/10.1167/iovs.09-3434
Activated CD11b+ CD15+ Granulocytes Increase in the Blood of Patients with Uveal Melanoma Free
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Kyle C. McKenna; Kelly M. Beatty; Richard A. Bilonick; Lynn Schoenfield; Kira L. Lathrop; Arun D. Singh
Tags: antigens, cd15, macrophage-1 antigen, uveal melanoma, granulocytes, t-lymphocytes
Investigative Ophthalmology & Visual Science September 2009, Vol.50, 4295-4303. doi:https://doi.org/10.1167/iovs.08-3012

Lens

Confocal Microscopy Reveals Zones of Membrane Remodeling in the Outer Cortex of the Human Lens Free
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Julie C. Lim; Kerry L. Walker; Trevor Sherwin; Kevin L. Schey; Paul J. Donaldson
Tags: lens (device), lens, crystalline, microscopy, confocal, tissue membrane, cell nucleus
Investigative Ophthalmology & Visual Science September 2009, Vol.50, 4304-4310. doi:https://doi.org/10.1167/iovs.09-3435
A New Fgf10 Mutation in the Mouse Leads to Atrophy of the Harderian Gland and Slit-Eye Phenotype in Heterozygotes: A Novel Model for Dry-Eye Disease? Free
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Oliver Puk; Irene Esposito; Torben Söker; Jana Löster; Birgit Budde; Peter Nürnberg; Dian Michel-Soewarto; Helmut Fuchs; Eckhard Wolf; Martin Hrabé de Angelis; Jochen Graw
Tags: atrophy, dry eye syndromes, eye, fgf10 protein, human, harderian gland
Investigative Ophthalmology & Visual Science September 2009, Vol.50, 4311-4318. doi:https://doi.org/10.1167/iovs.09-3451
Age-Related Changes in the Spatial Distribution of Human Lens α-Crystallin Products by MALDI Imaging Mass Spectrometry Free
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Angus C. Grey; Kevin L. Schey
Tags: crystallins, diagnostic imaging, lens, crystalline, spectrometry, mass, matrix-assisted laser desorption-ionization, lens (device)
Investigative Ophthalmology & Visual Science September 2009, Vol.50, 4319-4329. doi:https://doi.org/10.1167/iovs.09-3522
Regional Differences in Store-Operated Ca2+ Entry in the Epithelium of the Intact Human Lens Free
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Jeremy D. Rhodes; Sarah L. Russell; Christopher D. Illingworth; George Duncan; I. Michael Wormstone
Tags: epithelium, geographic difference, lens, crystalline, lens epithelial cell, epithelial cells
Investigative Ophthalmology & Visual Science September 2009, Vol.50, 4330-4336. doi:https://doi.org/10.1167/iovs.08-3222

Retina

Feasibility of Microelectrode Array (MEA) Based on Silicone-Polyimide Hybrid for Retina Prosthesis Free
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Eui Tae Kim; Cinoo Kim; Seung Woo Lee; Jong-Mo Seo; Hum Chung; Sung June Kim
Tags: microelectrodes, prostheses, silicones, retina, implantation procedure
Investigative Ophthalmology & Visual Science September 2009, Vol.50, 4337-4341. doi:https://doi.org/10.1167/iovs.08-2500
Correlation of Genetic and Clinical Findings in Spanish Patients with X-linked Juvenile Retinoschisis Free
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Rosa Riveiro-Alvarez; Maria-Jose Trujillo-Tiebas; Ascension Gimenez-Pardo; Maria Garcia-Hoyos; Miguel-Angel Lopez-Martinez; Jana Aguirre-Lamban; Blanca Garcia-Sandoval; Silvia Vazquez-Fernandez del Pozo; Diego Cantalapiedra; Almudena Avila-Fernandez; Montserrat Baiget; Carmen Ramos; Carmen Ayuso
Tags: family, genetics, haplotypes, mutation, spanish
Investigative Ophthalmology & Visual Science September 2009, Vol.50, 4342-4350. doi:https://doi.org/10.1167/iovs.09-3418
Wall-to-Lumen Ratio of Retinal Arterioles and Arteriole-to-Venule Ratio of Retinal Vessels in Patients with Cerebrovascular Damage Free
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Delia Baleanu; Martin Ritt; Joanna Harazny; Josef Heckmann; Roland E. Schmieder; Georg Michelson
Tags: arteriole, hypertension, retinal vessels, venule
Investigative Ophthalmology & Visual Science September 2009, Vol.50, 4351-4359. doi:https://doi.org/10.1167/iovs.08-3266
Age-Related Decline in Rod Phototransduction Sensitivity in Rhesus Monkeys Fed an n-3 Fatty Acid–Deficient Diet Free
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Brett G. Jeffrey; Martha Neuringer
Tags: diet, macaca mulatta, omega-3 fatty acids, photopsia, phototransduction
Investigative Ophthalmology & Visual Science September 2009, Vol.50, 4360-4367. doi:https://doi.org/10.1167/iovs.09-3640
Evaluation of 9-cis-Retinyl Acetate Therapy in Rpe65 −/− Mice Free
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Tadao Maeda; Akiko Maeda; Gemma Casadesus; Krzysztof Palczewski; Philippe Margaron
Tags: mice, retinoids, acetates, vision
Investigative Ophthalmology & Visual Science September 2009, Vol.50, 4368-4378. doi:https://doi.org/10.1167/iovs.09-3700
Clinical and Molecular Evaluation of Probands and Family Members with Familial Exudative Vitreoretinopathy Free
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F. Nienke Boonstra; C. Erik van Nouhuys; José Schuil; Ilse J. de Wijs; Kim P. van der Donk; Kostas Nikopoulos; Arijit Mukhopadhyay; Hans Scheffer; Mauk A. D. Tilanus; Frans P. M. Cremers; Lies H. Hoefsloot
Tags: familial exudative vitreoretinopathies, family, proband
Investigative Ophthalmology & Visual Science September 2009, Vol.50, 4379-4385. doi:https://doi.org/10.1167/iovs.08-3320
Retinal Pigment Epithelium Defects in Humans and Mice with Mutations in MYO7A: Imaging Melanosome-Specific Autofluorescence Free
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Daniel Gibbs; Artur V. Cideciyan; Samuel G. Jacobson; David S. Williams
Tags: autofluorescence, diagnostic imaging, melanosomes, mice, mutation
Investigative Ophthalmology & Visual Science September 2009, Vol.50, 4386-4393. doi:https://doi.org/10.1167/iovs.09-3471
Supranormal Electroretinogram in F at-1 Mice with Retinas Enriched in Docosahexaenoic Acid and n-3 Very Long Chain Fatty Acids (C24–C36) Free
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Miyoung Suh; Yves Sauvé; Krystal J. Merrells; Jing X. Kang; David W. L. Ma
Tags: docosahexaenoic acids, electroretinography, fatty acids, mice, retina
Investigative Ophthalmology & Visual Science September 2009, Vol.50, 4394-4401. doi:https://doi.org/10.1167/iovs.08-2565
Supernormal ERG Oscillatory Potentials in Transgenic Rabbit with Rhodopsin P347L Mutation and Retinal Degeneration Free
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Takao Sakai; Mineo Kondo; Shinji Ueno; Toshiyuki Koyasu; Keiichi Komeima; Hiroko Terasaki
Tags: electroretinography, erg protein, human, oryctolagus cuniculus, rhodopsin, retinal degeneration
Investigative Ophthalmology & Visual Science September 2009, Vol.50, 4402-4409. doi:https://doi.org/10.1167/iovs.09-3458

Retinal Cell Biology

Involvement of Hyaluronan and Its Receptor CD44 with Choroidal Neovascularization Free
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Hiroshi Mochimaru; Eri Takahashi; Nobuo Tsukamoto; Junichiro Miyazaki; Tomonori Yaguchi; Takashi Koto; Toshihide Kurihara; Kousuke Noda; Yoko Ozawa; Takatsugu Ishimoto; Yutaka Kawakami; Hidenobu Tanihara; Hideyuki Saya; Susumu Ishida; Kazuo Tsubota
Tags: cd44 antigens, choroidal neovascularization
Investigative Ophthalmology & Visual Science September 2009, Vol.50, 4410-4415. doi:https://doi.org/10.1167/iovs.08-3044
Sphingosine-1-Phosphate Is a Key Regulator of Proliferation and Differentiation in Retina Photoreceptors Free
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Gisela E. Miranda; Carolina E. Abrahan; Luis E. Politi; Nora P. Rotstein
Tags: photoreceptors, glial cell-line derived neurotrophic factor, retina, sphingosine-1-phosphate phosphatase
Investigative Ophthalmology & Visual Science September 2009, Vol.50, 4416-4428. doi:https://doi.org/10.1167/iovs.09-3388
Müller Cell Reactivity and Photoreceptor Cell Death Are Reduced after Experimental Retinal Detachment Using an Inhibitor of the Akt/mTOR Pathway Free
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Geoffrey P. Lewis; Ethan A. Chapin; Jiyun Byun; Gabriel Luna; David Sherris; Steven K. Fisher
Tags: mtor serine-threonine kinases, photoreceptors, proto-oncogene proteins c-akt, retina, retinal detachment
Investigative Ophthalmology & Visual Science September 2009, Vol.50, 4429-4435. doi:https://doi.org/10.1167/iovs.09-3445
Primary Culture of Human Blood–Retinal Barrier Cells and Preliminary Study of APOBEC3 Expression: An In Vitro Study Free
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Haotian Lin; Zhenping Zhang; Hui Zhang; Pisong Yan; Qilin Wang; Ling Bai
Tags: blood-retinal barrier, polymerase chain reaction, proteins, retina, reverse transcriptase polymerase chain reaction
Investigative Ophthalmology & Visual Science September 2009, Vol.50, 4436-4443. doi:https://doi.org/10.1167/iovs.08-3169
Regulation of Dynamic Behavior of Retinal Microglia by CX3CR1 Signaling Free
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Katharine J. Liang; Jung Eun Lee; Yunqing D. Wang; Wenxin Ma; Aurora M. Fontainhas; Robert N. Fariss; Wai T. Wong
Tags: microglia, signal transduction, wounds and injuries, laser injuries, regulation
Investigative Ophthalmology & Visual Science September 2009, Vol.50, 4444-4451. doi:https://doi.org/10.1167/iovs.08-3357
Effects of Thrombin on RPE Cells Are Mediated by Transactivation of Growth Factor Receptors Free
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Margrit Hollborn; Carola Petto; Anja Steffen; Susanne Trettner; Andrea Bendig; Peter Wiedemann; Andreas Bringmann; Leon Kohen
Tags: retinal pigment cell, thrombin, vascular endothelial growth factor a, growth factor receptors, trans-activation (genetics)
Investigative Ophthalmology & Visual Science September 2009, Vol.50, 4452-4459. doi:https://doi.org/10.1167/iovs.08-3194
Endogenous Elevation of Homocysteine Induces Retinal Neuron Death in the Cystathionine-β-Synthase Mutant Mouse Free
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Preethi S. Ganapathy; Brent Moister; Penny Roon; Barbara A. Mysona; Jennifer Duplantier; Ying Dun; Tracy K. V. E. Moister; Marlena J. Farley; Puttur D. Prasad; Kebin Liu; Sylvia B. Smith
Tags: homocysteine, mice, retina, cystathionine, neuron death
Investigative Ophthalmology & Visual Science September 2009, Vol.50, 4460-4470. doi:https://doi.org/10.1167/iovs.09-3402
Activation of the β-Catenin Signaling Pathway and Its Impact on RPE Cell Cycle Free
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Kerstin Steindl-Kuscher; Walter Krugluger; Michael E. Boulton; Paulina Haas; Karl Schrattbauer; Hans Feichtinger; Wolfram Adlassnig; Susanne Binder
Tags: cell cycle, cyclin d1, flow cytometry, growth factor, insulin-like growth factor i
Investigative Ophthalmology & Visual Science September 2009, Vol.50, 4471-4476. doi:https://doi.org/10.1167/iovs.08-3139

Visual Neuroscience

Light Responses in Rods of Vitamin A–Deprived Xenopus Free
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Eduardo Solessio; Yumiko Umino; David A. Cameron; Ellis Loew; Gustav A. Engbretson; Barry E. Knox; Robert B. Barlow
Tags: rod photoreceptors, vitamin a, xenopus
Investigative Ophthalmology & Visual Science September 2009, Vol.50, 4477-4486. doi:https://doi.org/10.1167/iovs.08-3186
An fMRI Study of Word-Level Recognition and Processing in Patients with Age-Related Macular Degeneration Free
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Janet P. Szlyk; Deborah M. Little
Tags: age-related macular degeneration, diagnostic imaging, functional magnetic resonance imaging, word recognition, prefrontal cortex
Investigative Ophthalmology & Visual Science September 2009, Vol.50, 4487-4495. doi:https://doi.org/10.1167/iovs.08-2258

Visual Psychophysics and Physiological Optics

Guttman Scale Analysis of the Distance Vision Scale Free
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Clinical Trials

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