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Anatomy and Pathology/Oncology

Regulation of VEGF-A in Uveal Melanoma Free
PDF
Mariam el Filali; Guy S. O. A. Missotten; Willem Maat; Long V. Ly; Gregorius P. M. Luyten; Pieter A. van der Velden; Martine J. Jager
Tags: vascular endothelial growth factor a, uveal melanoma, hypoxia, neoplasms, cell lines
Investigative Ophthalmology & Visual Science May 2010, Vol.51, 2329-2337. doi:https://doi.org/10.1167/iovs.09-4739

Biochemistry and Molecular Biology

Association of Whirlin with Cav1.3 (α1D) Channels in Photoreceptors, Defining a Novel Member of the Usher Protein Network Free
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Ferry F. J. Kersten; Erwin van Wijk; Jeroen van Reeuwijk; Bert van der Zwaag; Tina Märker; Theo A. Peters; Nicholas Katsanis; Uwe Wolfrum; Jan E. E. Keunen; Ronald Roepman; Hannie Kremer
Tags: photoreceptors, proteins, retina
Investigative Ophthalmology & Visual Science May 2010, Vol.51, 2338-2346. doi:https://doi.org/10.1167/iovs.09-4650
Time-Lapse Imaging of Retinal Angiogenesis Reveals Decreased Development and Progression of Neovascular Sprouting by Anecortave Desacetate Free
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Noriyuki Unoki; Tomoaki Murakami; Ken Ogino; Masayuki Nukada; Nagahisa Yoshimura
Tags: anecortave, angiogenesis, diagnostic imaging, vascular endothelial growth factor a, cell motility
Investigative Ophthalmology & Visual Science May 2010, Vol.51, 2347-2355. doi:https://doi.org/10.1167/iovs.09-4158
Structural Effects of Fibulin 5 Missense Mutations Associated with Age-Related Macular Degeneration and Cutis Laxa Free
PDF
Richard P. O. Jones; Caroline Ridley; Thomas A. Jowitt; Ming-Chuan Wang; Marjorie Howard; Nicoletta Bobola; Tao Wang; Paul N. Bishop; Cay M. Kielty; Clair Baldock; Andrew J. Lotery; Dorothy Trump
Tags: cutis laxa, fibulin, age-related macular degeneration, proteins, missense mutation
Investigative Ophthalmology & Visual Science May 2010, Vol.51, 2356-2362. doi:https://doi.org/10.1167/iovs.09-4620
High Molecular-Weight Gelatinase Species of Human Bruch's Membrane: Compositional Analyses and Age-Related Changes Free
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Ali A. Hussain; Yunhee Lee; John Marshall
Tags: bruch's basal membrane, gelatinases, molecular mass, gelatinase a, gelatinase b
Investigative Ophthalmology & Visual Science May 2010, Vol.51, 2363-2371. doi:https://doi.org/10.1167/iovs.09-4259
Visual Arrestin 1 Contributes to Cone Photoreceptor Survival and Light Adaptation Free
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Bruce M. Brown; Teresa Ramirez; Lawrence Rife; Cheryl M. Craft
Tags: arrestin, electroretinography, light adaptation, mice, retinal cone
Investigative Ophthalmology & Visual Science May 2010, Vol.51, 2372-2380. doi:https://doi.org/10.1167/iovs.09-4895

Clinical and Epidemiologic Research

Rose Bengal Staining of the Temporal Conjunctiva Differentiates Sjögren's Syndrome from Keratoconjunctivitis Sicca Free
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Barbara Caffery; Trefford Simpson; Sunny Wang; Denis Bailey; John McComb; John Rutka; Allan Slomovic; Arthur Bookman
Tags: conjunctiva, keratoconjunctivitis sicca, rose bengal, sjogren's syndrome, peeling skin syndrome
Investigative Ophthalmology & Visual Science May 2010, Vol.51, 2381-2387. doi:https://doi.org/10.1167/iovs.09-4188
Alterations in the Intraocular Cytokine Milieu after Intravitreal Bevacizumab Free
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Farzin Forooghian; Peter J. Kertes; Kenneth T. Eng; Elvira Agrón; Emily Y. Chew
Tags: bevacizumab, cytokine
Investigative Ophthalmology & Visual Science May 2010, Vol.51, 2388-2392. doi:https://doi.org/10.1167/iovs.09-4065
An Ecological Correlation Study of Late Age-Related Macular Degeneration and the Complement Factor H Y402H Polymorphism Free
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Bareng A. S. Nonyane; Dorothea Nitsch; John C. Whittaker; Reecha Sofat; Liam Smeeth; Usha Chakravarthy; Astrid E. Fletcher
Tags: age-related macular degeneration, complement factor h, correlation studies, gene frequency, polymorphism
Investigative Ophthalmology & Visual Science May 2010, Vol.51, 2393-2402. doi:https://doi.org/10.1167/iovs.09-4228

Cornea

Screening of Forme Fruste Keratoconus with the Ocular Response Analyzer Free
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Cedric Schweitzer; Cynthia J. Roberts; Ashraf M. Mahmoud; Joseph Colin; Sylvie Maurice-Tison; Julien Kerautret
Tags: cornea, eye, keratoconus, screening, air pressure
Investigative Ophthalmology & Visual Science May 2010, Vol.51, 2403-2410. doi:https://doi.org/10.1167/iovs.09-3689
Effects of Topical and Subconjunctival Bevacizumab in High-Risk Corneal Transplant Survival Free
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Mohammad H. Dastjerdi; Daniel R. Saban; Andre Okanobo; Nambi Nallasamy; Zahra Sadrai; Sunil K. Chauhan; Amir R. Hajrasouliha; Reza Dana
Tags: bevacizumab, keratoplasty, cornea
Investigative Ophthalmology & Visual Science May 2010, Vol.51, 2411-2417. doi:https://doi.org/10.1167/iovs.09-3745
Application of a Novel Interferometric Method to Investigate the Relation between Lipid Layer Thickness and Tear Film Thinning Free
PDF
P. Ewen King-Smith; Erich A. Hinel; Jason J. Nichols
Tags: lipids, tear film finding, emulsions
Investigative Ophthalmology & Visual Science May 2010, Vol.51, 2418-2423. doi:https://doi.org/10.1167/iovs.09-4387
Reversal of Second-hand Cigarette Smoke–Induced Impairment of Corneal Wound Healing by Thymosin β4 Combined with Anti-inflammatory Agents Free
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Hongwei Yuan; Chongze Ma; Lisa Moinet; Noboru Sato; Manuela Martins-Green
Tags: actins, anti-inflammatory agents, cigarette smoke, cornea, corneal epithelial cells
Investigative Ophthalmology & Visual Science May 2010, Vol.51, 2424-2435. doi:https://doi.org/10.1167/iovs.09-3692
Differential Distribution of Blood and Lymphatic Vessels in the Murine Cornea Free
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Tatiana Ecoiffier; Don Yuen; Lu Chen
Tags: cornea, lymphatic vessels, nose
Investigative Ophthalmology & Visual Science May 2010, Vol.51, 2436-2440. doi:https://doi.org/10.1167/iovs.09-4505
Induction of IL-6 in Transcriptional Networks in Corneal Epithelial Cells after Herpes Simplex Virus Type 1 Infection Free
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Yuki Terasaka; Dai Miyazaki; Keiko Yakura; Tomoko Haruki; Yoshitsugu Inoue
Tags: corneal epithelial cells, human herpesvirus 1, infections, interleukin-6, transcription, genetic
Investigative Ophthalmology & Visual Science May 2010, Vol.51, 2441-2449. doi:https://doi.org/10.1167/iovs.09-4624
Intracellular Thiol Redox Status Regulates Lymphangiogenesis and Dictates Corneal Limbal Graft Survival Free
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Akiko Fukumoto; Kazuichi Maruyama; Tony Walsh; Kentaro Kajiya; Junji Hamuro; Patricia A. D'Amore; Shigeru Kinoshita
Tags: cornea, graft survival, lymphangiogenesis, lymphatic vessels, oxidation-reduction
Investigative Ophthalmology & Visual Science May 2010, Vol.51, 2450-2458. doi:https://doi.org/10.1167/iovs.09-4618
Multimodal Nonlinear Imaging of the Human Cornea Free
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Florent Aptel; Nicolas Olivier; Ariane Deniset-Besseau; Jean-Marc Legeais; Karsten Plamann; Marie-Claire Schanne-Klein; Emmanuel Beaurepaire
Tags: cornea, diagnostic imaging, edema, harmonics, excitation
Investigative Ophthalmology & Visual Science May 2010, Vol.51, 2459-2465. doi:https://doi.org/10.1167/iovs.09-4586
Molecular Mechanism of Proinflammatory Cytokine-Mediated Squamous Metaplasia in Human Corneal Epithelial Cells Free
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Shimin Li; Marianne Gallup; Ying-Ting Chen; Nancy A. McNamara
Tags: corneal epithelial cells, cytokine, metaplasia, cyclic amp-responsive dna-binding protein, proteins
Investigative Ophthalmology & Visual Science May 2010, Vol.51, 2466-2475. doi:https://doi.org/10.1167/iovs.09-4677

Eye Movements, Strabismus, Amblyopia and Neuro-ophthalmology

Occurrence of Physiologic Gaze-Evoked Nystagmus at Small Angles of Gaze Free
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Chad A. Whyte; Anne Marie Petrock; Michael Rosenberg
Tags: gaze, gaze-evoked nystagmus, pathologic nystagmus
Investigative Ophthalmology & Visual Science May 2010, Vol.51, 2476-2478. doi:https://doi.org/10.1167/iovs.08-3241
Insulin-like Growth Factor-1 and Cardiotrophin 1 Increase Strength and Mass of Extraocular Muscle in Juvenile Chicken Free
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Tian Li; Larisa M. Wiggins; Christopher S. von Bartheld
Tags: chickens, insulin-like growth factor i, child, muscle of orbit, muscle
Investigative Ophthalmology & Visual Science May 2010, Vol.51, 2479-2486. doi:https://doi.org/10.1167/iovs.09-4414
Changes to Control of Adaptive Gait in Individuals with Long-standing Reduced Stereoacuity Free
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John G. Buckley; Gurvinder K. Panesar; Michael J. MacLellan; Ian E. Pacey; Brendan T. Barrett
Tags: eye, gait, amblyopia
Investigative Ophthalmology & Visual Science May 2010, Vol.51, 2487-2495. doi:https://doi.org/10.1167/iovs.09-3858
An Evaluation of the Amblyopia and Strabismus Questionnaire Using Rasch Analysis Free
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Marta Vianya-Estopa; David B. Elliott; Brendan T. Barrett
Tags: amblyopia, questionnaires, rasch model, strabismus
Investigative Ophthalmology & Visual Science May 2010, Vol.51, 2496-2503. doi:https://doi.org/10.1167/iovs.09-4381

Glaucoma

The Prostaglandin Transporter OATP2A1 Is Expressed in Human Ocular Tissues and Transports the Antiglaucoma Prostanoid Latanoprost Free
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Michaela E. Kraft; Hartmut Glaeser; Kathrin Mandery; Jörg König; Daniel Auge; Martin F. Fromm; Ursula Schlötzer-Schrehardt; Ulrich Welge-Lüssen; Friedrich E. Kruse; Oliver Zolk
Tags: body tissue, latanoprost, membrane transport proteins, prostaglandins, aqueous humor
Investigative Ophthalmology & Visual Science May 2010, Vol.51, 2504-2511. doi:https://doi.org/10.1167/iovs.09-4290
Commingling Analyses of Central Corneal Thickness and Adjusted Intraocular Pressure in an Older Australian Population Free
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Mohammad Lutfor Rahman; Catey Bunce; Paul R. Healey; Paul Mitchell; Pak C. Sham; Peter McGuffin; Ananth C. Viswanathan
Tags: cornea, intraocular pressure, eye
Investigative Ophthalmology & Visual Science May 2010, Vol.51, 2512-2518. doi:https://doi.org/10.1167/iovs.09-4270

Immunology and Microbiology

Minimum Inhibitory Concentrations of Standard and Novel Antimicrobials for Isolates from Bacterial Keratitis Free
PDF
Henri Sueke; Stephen Kaye; Timothy Neal; Conor Murphy; Amanda Hall; Dianne Whittaker; Stephen Tuft; Christopher Parry
Tags: antimicrobials, bacterial keratitis, minimum inhibitory concentration measurement, malnutrition-inflammation-cachexia syndrome, moxifloxacin
Investigative Ophthalmology & Visual Science May 2010, Vol.51, 2519-2524. doi:https://doi.org/10.1167/iovs.09-4638
A New HLA Extended Haplotype Containing the A*2910 Allele in Birdshot Retinochoroidopathy: Susceptibility Narrowed to the HLA Molecule Itself Free
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Béatrice Donvito; Dominique Monnet; Thierry Tabary; Emmanuelle Delair; Mélanie Vittier; Brigitte Réveil; Christophe Chiquet; Antoine P. Brézin; Jacques H. M. Cohen
Tags: alleles, disease susceptibility, haplotypes, human leukocyte antigens, molecule
Investigative Ophthalmology & Visual Science May 2010, Vol.51, 2525-2528. doi:https://doi.org/10.1167/iovs.09-4329
Suppression of Bystander T Helper 1 Cells by Iris Pigment Epithelium-Inducing Regulatory T Cells via Negative Costimulatory Signals Free
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Sunao Sugita; Shintaro Horie; Yukiko Yamada; Hiroshi Keino; Yoshihiko Usui; Masaru Takeuchi; Manabu Mochizuki
Tags: interprofessional education, pigment, regulatory t-lymphocytes, t-lymphocytes, iris
Investigative Ophthalmology & Visual Science May 2010, Vol.51, 2529-2536. doi:https://doi.org/10.1167/iovs.09-4460
Role of the Fas Pathway in Pseudomonas aeruginosa Keratitis Free
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Zimei Zhou; Minhao Wu; Ronald P. Barrett; Sharon A. McClellan; Yunfan Zhang; Linda D. Hazlett
Tags: cornea, enzyme-linked immunosorbent assay, in situ nick-end labeling, keratitis, mice
Investigative Ophthalmology & Visual Science May 2010, Vol.51, 2537-2547. doi:https://doi.org/10.1167/iovs.09-4152
Mechanisms of Immune Suppression for CD8+ T Cells by Human Corneal Endothelial Cells via Membrane-Bound TGFβ Free
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Yukiko Yamada; Sunao Sugita; Shintaro Horie; Satoru Yamagami; Manabu Mochizuki
Tags: tissue membrane, t-lymphocytes, regulatory t-lymphocytes, cornea, therapeutic immunosuppression
Investigative Ophthalmology & Visual Science May 2010, Vol.51, 2548-2557. doi:https://doi.org/10.1167/iovs.09-4233
Iris Pigment Epithelial Cells Express a Functional Lipopolysaccharide Receptor Complex Free
PDF
Jeanie J. Y. Chui; Monique W. M. Li; Nick Di Girolamo; John H. Chang; Peter J. McCluskey; Denis Wakefield
Tags: cd14 antigen, pigment, interprofessional education, toll-like receptor 4, epithelial cells
Investigative Ophthalmology & Visual Science May 2010, Vol.51, 2558-2567. doi:https://doi.org/10.1167/iovs.09-3923
Evaluation of Experimental Autoimmune Uveitis in Mice Treated with FTY720 Free
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Alessandra Gonçalves Commodaro; Jean Pierre S. Peron; Camila Takao Lopes; Christina Arslanian; Rubens Belfort, Jr; Luiz Vicente Rizzo; Valquiria Bueno
Tags: fingolimod, mice, uveitis, t-lymphocytes, eye
Investigative Ophthalmology & Visual Science May 2010, Vol.51, 2568-2574. doi:https://doi.org/10.1167/iovs.09-4769

Physiology and Pharmacology

Effect of Hypoxia on Susceptibility of RGC-5 Cells to Nitric Oxide Free
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Takaki Sato; Hidehiro Oku; Kazuhiro Tsuruma; Kozo Katsumura; Masamitsu Shimazawa; Hideaki Hara; Tetsuya Sugiyama; Tsunehiko Ikeda
Tags: glucose, hypoxia, sensory potential, snap-associated protein, human, nitric oxide
Investigative Ophthalmology & Visual Science May 2010, Vol.51, 2575-2586. doi:https://doi.org/10.1167/iovs.09-4303
Postmenopausal Hormone Therapy Increases Retinal Blood Flow and Protects the Retinal Nerve Fiber Layer Free
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Micheline C. Deschênes; Denise Descovich; Michèle Moreau; Louis Granger; George A. Kuchel; Tomi S. Mikkola; Gordon H. Fick; Sylvain Chemtob; Elvire Vaucher; Mark R. Lesk
Tags: estrogen, estrogen replacement therapy, optic disk, postmenopause, retina
Investigative Ophthalmology & Visual Science May 2010, Vol.51, 2587-2600. doi:https://doi.org/10.1167/iovs.09-3710

Retina

Inhibition of Apoptosis in Human Retinal Pigment Epithelial Cells Treated with Benzo(e)Pyrene, a Toxic Component of Cigarette Smoke Free
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Saffar Mansoor; Navin Gupta; A. Jayaprakash Patil; Maria Fernanda Estrago-Franco; Claudio Ramirez; Rafael Migon; Ashish Sapkal; Baruch D. Kuppermann; M. Cristina Kenney
Tags: apoptosis, caspase-3, caspase-9, cell survival, cigarette smoke
Investigative Ophthalmology & Visual Science May 2010, Vol.51, 2601-2607. doi:https://doi.org/10.1167/iovs.09-4121
Differential Macular Morphology in Patients with RPE65-, CEP290-, GUCY2D-, and AIPL1-Related Leber Congenital Amaurosis Free
PDF
Sirichai Pasadhika; Gerald A. Fishman; Edwin M. Stone; Martin Lindeman; Ruth Zelkha; Irma Lopez; Robert K. Koenekoop; Mahnaz Shahidi
Tags: language morphology, leber's amaurosis, morphology, mutation, optical coherence tomography
Investigative Ophthalmology & Visual Science May 2010, Vol.51, 2608-2614. doi:https://doi.org/10.1167/iovs.09-3734
Comparison of High-Resolution Melting Analysis with Denaturing High-Performance Liquid Chromatography for Mutation Scanning in the ABCA4 Gene Free
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Jana Aguirre-Lamban; Rosa Riveiro-Alvarez; Maria Garcia-Hoyos; Diego Cantalapiedra; Almudena Avila-Fernandez; Cristina Villaverde-Montero; Maria Jose Trujillo-Tiebas; Carmen Ramos; Carmen Ayuso
Tags: genes, high-resolution melt curve analysis, liquid chromatography, mutation, exons
Investigative Ophthalmology & Visual Science May 2010, Vol.51, 2615-2619. doi:https://doi.org/10.1167/iovs.09-4518
Genotypic Influences on Severity of Exudative Age-Related Macular Degeneration Free
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Nicolas Leveziel; Nathalie Puche; Florence Richard; John E. A. Somner; Jennyfer Zerbib; Sylvie Bastuji-Garin; Salomon Y. Cohen; Jean-François Korobelnik; José Sahel; Gisèle Soubrane; Pascale Benlian; Eric H. Souied
Tags: alleles, choroidal neovascularization, cicatrix, exudative age-related macular degeneration, genotype
Investigative Ophthalmology & Visual Science May 2010, Vol.51, 2620-2625. doi:https://doi.org/10.1167/iovs.09-4423
Inhibition of Retinoblastoma In Vitro and In Vivo with Conditionally Replicating Oncolytic Adenovirus H101 Free
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Xin Song; Yixiong Zhou; Renbing Jia; Xiaofang Xu; Haibo Wang; Jifan Hu; Shengfang Ge; Xianqun Fan
Tags: adenovirus infections, adenoviruses, retinoblastoma, neoplasms, proteins
Investigative Ophthalmology & Visual Science May 2010, Vol.51, 2626-2635. doi:https://doi.org/10.1167/iovs.09-3516
Apolipoprotein E Genotype Is Associated with Macular Pigment Optical Density Free
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Edward Loane; Gareth J. McKay; John M. Nolan; Stephen Beatty
Tags: apolipoprotein e genotype, optics, pigment, apolipoprotein e, diet
Investigative Ophthalmology & Visual Science May 2010, Vol.51, 2636-2643. doi:https://doi.org/10.1167/iovs.09-4397
Comparison of Retinal Thickness in Normal Eyes Using Stratus and Spectralis Optical Coherence Tomography Free
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Sandeep Grover; Ravi K. Murthy; Vikram S. Brar; Kakarla V. Chalam
Tags: eye, optical coherence tomography
Investigative Ophthalmology & Visual Science May 2010, Vol.51, 2644-2647. doi:https://doi.org/10.1167/iovs.09-4774
Acute Hyperglycemia-Induced Endothelial Dysfunction in Retinal Arterioles in Cats Free
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Kenji Sogawa; Taiji Nagaoka; Naohiro Izumi; Seigo Nakabayashi; Akitoshi Yoshida
Tags: arteriole, endothelial dysfunction, hyperglycemia, hyperglycemia, acute, retina circulation
Investigative Ophthalmology & Visual Science May 2010, Vol.51, 2648-2655. doi:https://doi.org/10.1167/iovs.09-4070
Autosomal Recessive Retinitis Pigmentosa with Early Macular Affectation Caused by Premature Truncation in PROM1 Free
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Jon Permanyer; Rafael Navarro; James Friedman; Esther Pomares; Joaquín Castro-Navarro; Gemma Marfany; Anand Swaroop; Roser Gonzàlez-Duarte
Tags: autosomal recessive inheritance, mutation, protein isoforms, retina, retinitis pigmentosa
Investigative Ophthalmology & Visual Science May 2010, Vol.51, 2656-2663. doi:https://doi.org/10.1167/iovs.09-4857
Increased Sequestration of Matrix Metalloproteinases in Ageing Human Bruch's Membrane: Implications for ECM Turnover Free
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Anupma Kumar; Austen El-Osta; Ali A. Hussain; John Marshall
Tags: aging, bruch's basal membrane, matrix metalloproteinases, gelatinases, gelatinase a
Investigative Ophthalmology & Visual Science May 2010, Vol.51, 2664-2670. doi:https://doi.org/10.1167/iovs.09-4195
Impact of Tumor-Associated Macrophages in LHBETATAG Mice on Retinal Tumor Progression: Relation to Macrophage Subtype Free
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Yolanda Piña; Hinda Boutrid; Timothy G. Murray; Martine J. Jager; Colleen M. Cebulla; Amy Schefler; Long V. Ly; Armando Alegret; Magda Celdran; William Feuer; Maria-Elena Jockovich
Tags: macrophages, mice, neoplasms, retinal neoplasms, gelatinase b
Investigative Ophthalmology & Visual Science May 2010, Vol.51, 2671-2677. doi:https://doi.org/10.1167/iovs.09-4255
Optimizing Hand-held Spectral Domain Optical Coherence Tomography Imaging for Neonates, Infants, and Children Free
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Ramiro S. Maldonado; Joseph A. Izatt; Neeru Sarin; David K. Wallace; Sharon Freedman; C. Michael Cotten; Cynthia A. Toth
Tags: child, diagnostic imaging, eye, infant, newborn
Investigative Ophthalmology & Visual Science May 2010, Vol.51, 2678-2685. doi:https://doi.org/10.1167/iovs.09-4403

Retinal Cell Biology

Proliferative Response of Microglia and Macrophages in the Adult Mouse Eye after Optic Nerve Lesion Free
PDF
Stefanie G. Wohl; Christian W. Schmeer; Otto W. Witte; Stefan Isenmann
Tags: bromodeoxyuridine, macrophages, microglia, optic nerve, retina
Investigative Ophthalmology & Visual Science May 2010, Vol.51, 2686-2696. doi:https://doi.org/10.1167/iovs.09-4537
Paracrine Modulation of CXCR4 by IGF-1 and VEGF: Implications for Choroidal Neovascularization Free
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Nilanjana Sengupta; Aqeela Afzal; Sergio Caballero; Kyung-Hee Chang; Lynn C. Shaw; Ji-Jing Pang; Vincent C. Bond; Imran Bhutto; Takayuki Baba; Gerard A. Lutty; Maria B. Grant
Tags: choroidal neovascularization, cxcr4 receptors, insulin-like growth factor i, stromal cell-derived factor 1, vascular endothelial growth factor a
Investigative Ophthalmology & Visual Science May 2010, Vol.51, 2697-2704. doi:https://doi.org/10.1167/iovs.09-4137
A High-Throughput Biophotonics Instrument to Screen for Novel Ocular Photosensitizing Therapeutic Agents Free
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Mark C. Butler; Patrick N. Itotia; Jack M. Sullivan
Tags: cell culture techniques, cell death, krypton, molecule, neovascularization, pathologic
Investigative Ophthalmology & Visual Science May 2010, Vol.51, 2705-2720. doi:https://doi.org/10.1167/iovs.08-2862
Chemotactic and Cytotoxic Effects of Minocycline on Human Retinal Pigment Epithelial Cells Free
PDF
Margrit Hollborn; Peter Wiedemann; Andreas Bringmann; Leon Kohen
Tags: minocycline, retinal pigment cell, platelet-derived growth factor, chemotaxis, triamcinolone
Investigative Ophthalmology & Visual Science May 2010, Vol.51, 2721-2729. doi:https://doi.org/10.1167/iovs.09-4661
Systemic Propranolol Reduces b-Wave Amplitude in the ERG and Increases IGF-1 Receptor Phosphorylation in Rat Retina Free
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Youde Jiang; Jena J. Steinle
Tags: electroretinography, insulin-like-growth factor i receptor, phosphorylation, propranolol, retina
Investigative Ophthalmology & Visual Science May 2010, Vol.51, 2730-2735. doi:https://doi.org/10.1167/iovs.09-4779
In Search of the Identity of the XAP-1 Antigen: A Protein Localized to Cone Outer Segments Free
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Suba Nookala; Rohit Gandrakota; Amira Wohabrebbi; XiaoFei Wang; Danielle Howell; Francesco Giorgianni; Sarka Beranova-Giorgianni; Dominic M. Desiderio; Monica M. Jablonski
Tags: antigens, proteins, retinal cone, western blotting, antibodies
Investigative Ophthalmology & Visual Science May 2010, Vol.51, 2736-2743. doi:https://doi.org/10.1167/iovs.09-4286
Visual Experience–Independent Functional Expression of NMDA Receptors in the Developing Rabbit Retina Free
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Yun-Chieh Chang; Chih-Yang Chen; Chuan-Chin Chiao
Tags: n-methyl-d-aspartate receptors, oryctolagus cuniculus, retina
Investigative Ophthalmology & Visual Science May 2010, Vol.51, 2744-2754. doi:https://doi.org/10.1167/iovs.09-4217
Epithelial-Mesenchymal Transition and Proliferation of Retinal Pigment Epithelial Cells Initiated upon Loss of Cell-Cell Contact Free
PDF
Shigeo Tamiya; LanHsin Liu; Henry J. Kaplan
Tags: epithelial to mesenchymal transition, retinal pigment cell, cadherins
Investigative Ophthalmology & Visual Science May 2010, Vol.51, 2755-2763. doi:https://doi.org/10.1167/iovs.09-4725

Visual Neuroscience

Post-illumination Pupil Response in Subjects without Ocular Disease Free
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Laxmikanth Kankipati; Christopher A. Girkin; Paul D. Gamlin
Tags: eye diseases, light, lighting, pupil, pupil reaction
Investigative Ophthalmology & Visual Science May 2010, Vol.51, 2764-2769. doi:https://doi.org/10.1167/iovs.09-4717
Interrelationship of Optical Coherence Tomography and Multifocal Visual-Evoked Potentials after Optic Neuritis Free
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Alexander Klistorner; Hemamalini Arvind; Raymond Garrick; Stuart L. Graham; Mark Paine; Con Yiannikas
Tags: optic neuritis, optical coherence tomography, retinal nerve fiber layer, recovery of function, eye
Investigative Ophthalmology & Visual Science May 2010, Vol.51, 2770-2777. doi:https://doi.org/10.1167/iovs.09-4577
Muscarinic Acetylcholine Receptor Localization and Activation Effects on Ganglion Response Properties Free
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Christianne E. Strang; Jordan M. Renna; Franklin R. Amthor; Kent T. Keyser
Tags: antibodies, ganglia, muscarinic acetylcholine receptor, oryctolagus cuniculus, retina
Investigative Ophthalmology & Visual Science May 2010, Vol.51, 2778-2789. doi:https://doi.org/10.1167/iovs.09-4771
Scotopic Electrophysiology of the Retina during Transient Hyperglycemia in Type 2 Diabetes Free
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Stig Kraglund Holfort; Kristian Klemp; Peter Kristian Kofoed; Birgit Sander; Michael Larsen
Tags: diabetes mellitus, type 2, electrophysiology, glucose, hyperglycemia, retina
Investigative Ophthalmology & Visual Science May 2010, Vol.51, 2790-2794. doi:https://doi.org/10.1167/iovs.09-4891

Visual Psychophysics and Physiological Optics

Retinal Straylight as a Function of Age and Ocular Biometry in Healthy Eyes Free
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Jos J. Rozema; Thomas J. T. P. Van den Berg; Marie-José Tassignon
Tags: biometry, eye, refraction, eye color
Investigative Ophthalmology & Visual Science May 2010, Vol.51, 2795-2799. doi:https://doi.org/10.1167/iovs.09-4056
Straylight before and after LASEK in Myopia: Changes in Retinal Straylight Free
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Jos J. Rozema; Tanja Coeckelbergh; Thomas J. T. P. Van den Berg; Rene Trau; Nathalie C. Duchateau; Sofie Lemmens; Marie-José Tassignon
Tags: keratectomy, subepithelial, laser-assisted, myopia, contact lenses, preoperative care, eye
Investigative Ophthalmology & Visual Science May 2010, Vol.51, 2800-2804. doi:https://doi.org/10.1167/iovs.09-4679
The Effect of the Asphericity of Myopic Laser Ablation Profiles on the Induction of Wavefront Aberrations Free
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Jens Bühren; Lana Nagy; Geunyoung Yoon; Scott MacRae; Thomas Kohnen; Krystel R. Huxlin
Tags: ablation, image quality, laser ablation, optics, polymethyl methacrylate
Investigative Ophthalmology & Visual Science May 2010, Vol.51, 2805-2812. doi:https://doi.org/10.1167/iovs.09-4604

Clinical Trials

Optic Disc Diameter Increases during Acute Elevations of Intraocular Pressure Free
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Ali Poostchi; Tracey Wong; Kenneth C. Y. Chan; Lance Kedzlie; Nisha Sachdev; Simon Nicholas; David F. Garway-Heath; Anthony P. Wells
Tags: diameter, glaucoma, intraocular pressure, optic disk, eye
Investigative Ophthalmology & Visual Science May 2010, Vol.51, 2313-2316. doi:https://doi.org/10.1167/iovs.09-3756
Small, Hard Macular Drusen and Peripheral Drusen: Associations with AMD Genotypes in the Inter99 Eye Study Free
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Inger Christine Munch; Jakob Ek; Line Kessel; Birgit Sander; Gitte Juul Almind; Karen Brøndum-Nielsen; Allan Linneberg; Michael Larsen
Tags: drusen, eye, genotype, retinal drusen
Investigative Ophthalmology & Visual Science May 2010, Vol.51, 2317-2321. doi:https://doi.org/10.1167/iovs.09-4482
Pretreatment with Intravitreal Triamcinolone before Laser for Diabetic Macular Edema: 6-Month Results of a Randomized, Placebo-Controlled Trial Free
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Mark C. Gillies; Ian L. McAllister; Meidong Zhu; Wanling Wong; Damien Louis; Jennifer J. Arnold; Tien Y. Wong
Tags: diabetic macular edema, eye, lasers, placebos, triamcinolone
Investigative Ophthalmology & Visual Science May 2010, Vol.51, 2322-2328. doi:https://doi.org/10.1167/iovs.09-4400

Point/Counterpoint

Point: A Critical Appraisal of the Lens Circulation Model—An Experimental Paradigm for Understanding the Maintenance of Lens Transparency? Free
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Paul J. Donaldson; Linda S. Musil; Richard T. Mathias
Tags: lens (device), lens, crystalline, transparency, comprehension
Investigative Ophthalmology & Visual Science May 2010, Vol.51, 2303-2306. doi:https://doi.org/10.1167/iovs.10-5350
Counterpoint: The Lens Fluid Circulation Model—A Critical Appraisal Free
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David C. Beebe; Roger J. W. Truscott
Tags: lens (device), lens, crystalline, fluid flow
Investigative Ophthalmology & Visual Science May 2010, Vol.51, 2306-2310. doi:https://doi.org/10.1167/iovs.10-5350a
Reply to: The Lens Fluid Circulation Model—A Critical Appraisal Free
PDF
Paul J. Donaldson; Linda S. Musil; Richard T. Mathias
Tags: lens (device), lens, crystalline
Investigative Ophthalmology & Visual Science May 2010, Vol.51, 2310-2312. doi:https://doi.org/10.1167/iovs.10-5350b
Reply to: A Critical Appraisal of the Lens Circulation Model—An Experimental Paradigm for Understanding the Maintenance of Lens Transparency? Free
PDF
David C. Beebe; Roger J. W. Truscott
Tags: comprehension, lens (device), lens, crystalline, transparency
Investigative Ophthalmology & Visual Science May 2010, Vol.51, 2312. doi:https://doi.org/10.1167/iovs.10-5350c
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