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Research Highlight

Targeting Host Pathways to Block HSV-1 at the Cornea Free
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Paul R. Kinchington
Investigative Ophthalmology & Visual Science February 2014, Vol.55, 716. doi:10.1167/iovs.14-13879

Anatomy and Pathology/Oncology

Enrichment of Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE1)-Positive Macrophages Around Blood Vessels in the Normal Human Sclera Free
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Simona L. Schlereth; Barbara Neuser; Albert Caramoy; Rafael S. Grajewski; Konrad R. Koch; Falk Schrödl; Claus Cursiefen; Ludwig M. Heindl
Tags: cd44 antigens, lymphatic vessels, macrophages, sclera, endothelium
Investigative Ophthalmology & Visual Science February 2014, Vol.55, 865-872. doi:10.1167/iovs.13-13453
Integration of Defocus by Dual Power Fresnel Lenses Inhibits Myopia in the Mammalian Eye Free
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Sally A. McFadden; Dennis Y. Tse; Hannah E. Bowrey; Amelia J. Leotta; Carly S. Lam; Christine F. Wildsoet; Chi-Ho To
Tags: eye, lens (device), lens, crystalline, myopia
Investigative Ophthalmology & Visual Science February 2014, Vol.55, 908-917. doi:10.1167/iovs.13-11724
Anatomical Manifestations of Primary Blast Ocular Trauma Observed in a Postmortem Porcine Model Free
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Daniel Sherwood; William E. Sponsel; Brian J. Lund; Walt Gray; Richard Watson; Sylvia L. Groth; Kimberly Thoe; Randolph D. Glickman; Matthew A. Reilly
Tags: autopsy, basic local alignment search tool, eye, ocular trauma, suidae
Investigative Ophthalmology & Visual Science February 2014, Vol.55, 1124-1132. doi:10.1167/iovs.13-13295

Biochemistry and Molecular Biology

Method Development for Quantification of Five Tear Proteins Using Selected Reaction Monitoring (SRM) Mass Spectrometry Free
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Simin Masoudi; Ling Zhong; Mark J. Raftery; Fiona J. Stapleton; Mark D. Willcox
Tags: mass spectrometry, peptides, proteins, spatial release from masking, mass or substance concentration per volume
Investigative Ophthalmology & Visual Science February 2014, Vol.55, 767-775. doi:10.1167/iovs.13-12777
Age-Related Changes of Cystatin C Expression and Polarized Secretion by Retinal Pigment Epithelium: Potential Age-Related Macular Degeneration Links Free
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Paul Kay; Yit C. Yang; Paul Hiscott; Donna Gray; Arvydas Maminishkis; Luminita Paraoan
Tags: bodily secretions, cystatin c measurement, age, proteins, age-related macular degeneration
Investigative Ophthalmology & Visual Science February 2014, Vol.55, 926-934. doi:10.1167/iovs.13-13239

Clinical and Epidemiologic Research

Seasonal Variations in the Progression of Myopia in Children Enrolled in the Correction of Myopia Evaluation Trial Free
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Jane Gwiazda; Li Deng; Ruth Manny; Thomas T. Norton
Tags: child, myopia, seasonal variation
Investigative Ophthalmology & Visual Science February 2014, Vol.55, 752-758. doi:10.1167/iovs.13-13029
The Clinical Spectrum of Microcystic Macular Edema Free
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Marloes C. Burggraaff; Jennifer Trieu; Willemien A. E. J. de Vries-Knoppert; Lisanne Balk; Axel Petzold
Tags: edema, age-related macular degeneration
Investigative Ophthalmology & Visual Science February 2014, Vol.55, 952-961. doi:10.1167/iovs.13-12912
Lens Power in a Population-Based Cross-Sectional Sample of Adults Aged 40 to 64 Years in the Shahroud Eye Study Free
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Rafael Iribarren; Ian G. Morgan; Hassan Hashemi; Mehdi Khabazkhoob; Mohammad Hassan Emamian; Mohammad Shariati; Akbar Fotouhi
Tags: adult, eye, lens (device), lens, crystalline, cornea
Investigative Ophthalmology & Visual Science February 2014, Vol.55, 1031-1039. doi:10.1167/iovs.13-13575
Prevalence and Risk Factors of Age-Related Macular Degeneration in Korea: The Korea National Health and Nutrition Examination Survey 2010–2011 Free
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Bum-Joo Cho; Jang Won Heo; Tae Wan Kim; Jeeyun Ahn; Hum Chung
Tags: age-related macular degeneration, korea, national health and nutrition examination survey, prevalence, risk factors
Investigative Ophthalmology & Visual Science February 2014, Vol.55, 1101-1108. doi:10.1167/iovs.13-13096

Cornea

Ocular Surface Symptoms in Veterans Returning From Operation Iraqi Freedom and Operation Enduring Freedom Free
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Yasha S. Modi; Qirat Qurban; Leonid Zlotcavitch; Roberto J. Echeverri; William Feuer; Hermes Florez; Anat Galor
Tags: signs and symptoms, veterans, risk factors, afghan campaign, iraq war, 2003-2011
Investigative Ophthalmology & Visual Science February 2014, Vol.55, 650-653. doi:10.1167/iovs.13-13330
Effects of Daily Irrigation on Corneal Epithelial Permeability and Adverse Events With Silicone Hydrogel Contact Lens Continuous Wear Free
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Meng C. Lin; Heather M. French; Andrew D. Graham; Timothy L. Sanders
Tags: adverse event, contact lenses, cornea, epithelium, hydrogel
Investigative Ophthalmology & Visual Science February 2014, Vol.55, 776-783. doi:10.1167/iovs.13-13508
The Suitability of Corneas Stored by Organ Culture for Penetrating Keratoplasty and Influence of Donor and Recipient Factors on 5-Year Graft Survival Free
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W. John Armitage; Mark N. A. Jones; Isaac Zambrano; Fiona Carley; Derek M. Tole
Tags: cornea, donors, graft survival, keratoplasty, penetrating, organ culture techniques
Investigative Ophthalmology & Visual Science February 2014, Vol.55, 784-791. doi:10.1167/iovs.13-13386
Development of Allele-Specific Gene-Silencing siRNAs for TGFBI Arg124Cys in Lattice Corneal Dystrophy Type I Free
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David G. Courtney; Sarah D. Atkinson; Johnny E. Moore; Eleonora Maurizi; Chiara Serafini; Graziella Pellegrini; Graeme C. Black; Forbes D. Manson; Gary H. F. Yam; Caroline J. MacEwen; Edwin H. A. Allen; W. H. Irwin McLean; C. B. Tara Moore
Tags: alleles, corneal epithelial cells, gene silencing, meretoja syndrome, pyrosequencing
Investigative Ophthalmology & Visual Science February 2014, Vol.55, 977-985. doi:10.1167/iovs.13-13279
Measurement of Difference Thresholds on the Ocular Surface Free
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Subam Basuthkar Sundar Rao; Trefford L. Simpson
Tags: contact lenses, cornea, lens (device), lens, crystalline, psychophysics
Investigative Ophthalmology & Visual Science February 2014, Vol.55, 1095-1100. doi:10.1167/iovs.13-12874
A Model for Tear Film Thinning With Osmolarity and Fluorescein Free
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Richard J. Braun; Nicholas R. Gewecke; Carolyn G. Begley; P. Ewen King-Smith; Javed I. Siddique
Tags: