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Anatomy and Pathology/Oncology

Endotoxin-Induced Uveitis is Partially Inhibited by Anti–IL-8 Antibody Treatment Free
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Manju J. Verma; Naofumi Mukaida; Ute Vollmer–Conna; Kouji Matsushima; Andrew Lloyd; Denis Wakefield
Tags: antibodies, endotoxins, interleukin-8, uveitis
Investigative Ophthalmology & Visual Science October 1999, Vol.40, 2465-2470. doi:
Microvascular Density in Predicting Survival of Patients with Choroidal and Ciliary Body Melanoma Free
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Teemu Mäkitie; Paula Summanen; Ahti Tarkkanen; Tero Kivelä
Tags: antibodies, cd34 antigens, ciliary body melanoma, epitopes, melanoma
Investigative Ophthalmology & Visual Science October 1999, Vol.40, 2471-2480. doi:

Biochemistry and Molecular Biology

Enhanced Secretory Group II PLA2 Activity in the Tears of Chronic Blepharitis Patients Free
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Cheol Hwa Song; Jae Sin Choi; Dae Kyong Kim; Jae Chan Kim
Tags: blepharitis
Investigative Ophthalmology & Visual Science October 1999, Vol.40, 2744-2748. doi:
Localization of the Mouse nob (no b-wave) Gene to the Centromeric Region of the X Chromosome Free
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Sophie I. Candille; Machelle T. Pardue; Maureen A. McCall; Neal S. Peachey; Ronald G. Gregg
Tags: genes, mice, x chromosomes
Investigative Ophthalmology & Visual Science October 1999, Vol.40, 2748-2751. doi:

Clinical and Epidemiologic Research

A Practical Method for Measuring Macular Pigment Optical Density Free
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Billy R. Wooten; Billy R. Hammond, Jr.; Richard I. Land; D. Max Snodderly
Tags: optics, pigment, lens (device), lens, crystalline
Investigative Ophthalmology & Visual Science October 1999, Vol.40, 2481-2489. doi:

Cornea

HSV-1 Migration in Latently Infected and Naive Rabbits after Penetrating Keratoplasty Free
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Xiaodong Zheng; Mary E. Marquart; Jeannette M. Loustch; Pulin Shah; Bruno Sainz; Arnab Ray; Richard J. O’Callaghan; Herbert E. Kaufman; James M. Hill
Tags: cornea, dna, human herpesvirus 1, keratoplasty, penetrating, oryctolagus cuniculus
Investigative Ophthalmology & Visual Science October 1999, Vol.40, 2490-2497. doi:
Inhibition of Rat Corneal Angiogenesis by 16-kDa Prolactin and by Endogenous Prolactin-like Molecules Free
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Zulma Dueñas; Luz Torner; Ana M. Corbacho; Alejandra Ochoa; Gabriel Gutiérrez–Ospina; Fernando López–Barrera; Fernando A. Barrios; Peter Berger; Gonzalo Martínez de la Escalera; Clapp Carmen
Tags: antibodies, corneal neovascularization, molecule, prolactin, cornea
Investigative Ophthalmology & Visual Science October 1999, Vol.40, 2498-2505. doi:
Tear Fluid Gelatinase B Activity Correlates with IL-1α Concentration and Fluorescein Clearance in Ocular Rosacea Free
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Adolfo A. Afonso; Lucia Sobrin; Dagoberto C. Monroy; Marie Selzer; Balakrishna Lokeshwar; Stephen C. Pflugfelder
Tags: drug clearance, fluorescein, gelatinase b, mass or substance concentration per volume, ocular rosacea
Investigative Ophthalmology & Visual Science October 1999, Vol.40, 2506-2512. doi:
TGF-β2 in Aqueous Humor Suppresses S-Phase Entry in Cultured Corneal Endothelial Cells Free
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Ko-Hua Chen; Deshea L. Harris; Nancy C. Joyce
Tags: aqueous humor, cornea, endothelial cells, s phase, thymidine
Investigative Ophthalmology & Visual Science October 1999, Vol.40, 2513-2519. doi:
Investigation of Corneal Ablation Efficiency Using Ultraviolet 213-nm Solid State Laser Pulses Free
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Geoffrey T. Dair; Wayne S. Pelouch; Paul P. van Saarloos; Darren J. Lloyd; Simone M. Paz Linares; Fred Reinholz
Tags: ablation, cornea, lasers, solids
Investigative Ophthalmology & Visual Science October 1999, Vol.40, 2752-2756. doi:

Eye Movements, Strabismus, Amblyopia and Neuro-ophthalmology

Comparing Pupil Function with Visual Function in Patients with Leber’s Hereditary Optic Neuropathy Free
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Fion D. Bremner; Josephine Shallo–Hoffmann; Paul Riordan–Eva; Stephen E. Smith
Tags: optic atrophy, hereditary, leber, pupil, vision, pupil reaction
Investigative Ophthalmology & Visual Science October 1999, Vol.40, 2528-2534. doi:
Effects of Monocular Enucleation on Parvalbumin in Rat Visual System during Postnatal Development Free
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Yoritsugu Hada; Yuko Yamada; Kazuyuki Imamura; Nobuko Mataga; Yasuyoshi Watanabe; Misao Yamamoto
Tags: cellular enucleation, enucleation procedure, parvalbumins, visual system, neurons
Investigative Ophthalmology & Visual Science October 1999, Vol.40, 2535-2545. doi:
The Incidence and Waveform Characteristics of Periodic Alternating Nystagmus in Congenital Nystagmus Free
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Josephine Shallo–Hoffmann; Mary Faldon; Ronald J. Tusa
Tags: congenital nystagmus, eye movement, incidence, nystagmus, periodic alternating, pathologic nystagmus
Investigative Ophthalmology & Visual Science October 1999, Vol.40, 2546-2553. doi:
Measurement of Recti Eye Muscle Paths by Magnetic Resonance Imaging in Highly Myopic and Normal Subjects Free
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Thomas H. Krzizok; Bernd U. Schroeder
Tags: magnetic resonance imaging, muscle of orbit, orbit, gaze, eye
Investigative Ophthalmology & Visual Science October 1999, Vol.40, 2554-2560. doi:
Direct Injection of Liposome-Encapsulated Doxorubicin Optimizes Chemomyectomy in Rabbit Eyelid Free
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Linda K. McLoon; Jonathan D. Wirtschafter
Tags: doxorubicin, eyelid, liposomes, oryctolagus cuniculus, injections
Investigative Ophthalmology & Visual Science October 1999, Vol.40, 2561-2567. doi:

Glaucoma

Reduction of Collagen Type I in the Ciliary Muscle of Inflamed Monkey Eyes Free
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Takeshi Sagara; Dan D. Gaton; James D. Lindsey; B’Ann True Gabelt; Paul L. Kaufman; Robert N. Weinreb
Tags: cercopithecidae, ciliary muscle, collagen type i, eye, immunohistochemistry
Investigative Ophthalmology & Visual Science October 1999, Vol.40, 2568-2576. doi:
Modulation of Myocilin/TIGR Expression in Human Trabecular Meshwork Free
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Ernst R. Tamm; Paul Russell; David L. Epstein; Douglas H. Johnson; Joram Piatigorsky
Tags: myoc gene, rna, rna, messenger, trabecular meshwork, cell culture techniques
Investigative Ophthalmology & Visual Science October 1999, Vol.40, 2577-2582. doi:

Immunology and Microbiology

IL-1 and TNF Receptor–Deficient Mice Show Decreased Inflammation in an Immune Complex Model of Uveitis Free
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Beatriz E. Brito; Leslie M. O’Rourke; Yuzhen Pan; Joy Anglin; Stephen R. Planck; James T. Rosenbaum
Tags: antigen-antibody complex, inflammation, interleukin-1, mice, tumor necrosis factor receptor
Investigative Ophthalmology & Visual Science October 1999, Vol.40, 2583-2589. doi:
T-Cell–Mediated Immune Responses in Alloepithelial Rejection after Murine Keratoepithelioplasty Free
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Dai Miyazaki; Yoshitsugu Inoue; Yu–Feng Yao; Annabelle A. Okada; Yoshikazu Shimomura; Kozaburo Hayashi; Yasuo Tano; Yuichi Ohashi
Tags: rejection (psychology), t-lymphocytes, immune response
Investigative Ophthalmology & Visual Science October 1999, Vol.40, 2590-2597. doi:
Entry of Human Cytomegalovirus into Retinal Pigment Epithelial and Endothelial Cells by Endocytosis Free
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Bahram Bodaghi; Marlea E. P. Slobbe–vanDrunen; Andrzei Topilko; Emmanuelle Perret; Renée C. R. M. Vossen; Maria C. E. van Dam–Mieras; Donato Zipeto; Jean-Louis Virelizier; Phuc LeHoang; Cathrien A. Bruggeman; Susan Michelson
Tags: cell nucleus, endocytosis, endothelial cells, epithelium, fluorescent antibody technique
Investigative Ophthalmology & Visual Science October 1999, Vol.40, 2598-2607. doi:
Protection against Murine Cytomegalovirus Retinitis by Adoptive Transfer of Virus-Specific CD8+ T Cells Free
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John E. Bigger; Minoru Tanigawa; Charles A. Thomas, III; Sally S. Atherton
Tags: adoptive transfer, cytomegalovirus retinitis, retinitis, t-lymphocytes, viruses
Investigative Ophthalmology & Visual Science October 1999, Vol.40, 2608-2613. doi:
Role of CD4+ T Cells in Immunobiology of Orthotopic Corneal Transplants in Mice Free
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Jun Yamada; Iwao Kurimoto; J. Wayne Streilein
Tags: allografting, cornea, keratoplasty, mice, t-lymphocytes
Investigative Ophthalmology & Visual Science October 1999, Vol.40, 2614-2621. doi:
Uveitis Induced by Lymphocytes Sensitized against a Transgenically Expressed Lens Protein Free
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James C. Lai; Mark C. Lobanoff; Atsuki Fukushima; Eric F. Wawrousek; Chi–Chao Chan; Scott M. Whitcup; Igal Gery
Tags: crystallins, lymphocytes, mice, uveitis, eye inflammation
Investigative Ophthalmology & Visual Science October 1999, Vol.40, 2735-2739. doi:

Physiology and Pharmacology

Correlation between Morphological and Functional Retinal Impairment in Multiple Sclerosis Patients Free
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Vincenzo Parisi; Gianluca Manni; Maria Spadaro; Gaspare Colacino; Rita Restuccia; Stefano Marchi; Massimo G. Bucci; Francesco Pierelli
Tags: evoked potentials, visual, eye, impairment, multiple sclerosis, optic neuritis
Investigative Ophthalmology & Visual Science October 1999, Vol.40, 2520-2527. doi:
Flow after Prostaglandin E1 Is Mediated by Receptor-Coupled Adenylyl Cyclase in Human Anterior Segments Free
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Berlinde G. Dijkstra; Andrea Schneemann; Philip F. Hoyng
Tags: adenylate cyclase, alprostadil, fluid flow, perfusion, cyclic amp
Investigative Ophthalmology & Visual Science October 1999, Vol.40, 2622-2626. doi:
Increased Interleukin-6 in Aqueous Humor of Neovascular Glaucoma Free
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Ko-Hua Chen; Chih-Chiau Wu; Sayon Roy; Shui-Mei Lee; Jorn-Hon Liu
Tags: aqueous humor, glaucoma, neovascular, interleukin-6, tumor necrosis factors
Investigative Ophthalmology & Visual Science October 1999, Vol.40, 2627-2632. doi:
Optic Nerve Oxygen Tension in Pigs and the Effect of Carbonic Anhydrase Inhibitors Free
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Einar Stefánsson; Peter Koch Jensen; Thor Eysteinsson; Kurt Bang; Jens F. Kiilgaard; Jens Dollerup; Erik Scherfig; Morten la Cour
Tags: arterial oxygen tension, carbon dioxide, carbonic anhydrase inhibitors, dorzolamide, optic nerve
Investigative Ophthalmology & Visual Science October 1999, Vol.40, 2756-2761. doi:

Retina

Amplitude Increase of the Multifocal Electroretinogram during Light Adaptation Free
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Mineo Kondo; Yozo Miyake; Chang-Hua Piao; Atsuhiro Tanikawa; Masayuki Horiguchi; Hiroko Terasaki
Tags: electroretinography, light adaptation, retina
Investigative Ophthalmology & Visual Science October 1999, Vol.40, 2633-2637. doi:
Multifocal Electroretinogram Delays Reveal Local Retinal Dysfunction in Early Diabetic Retinopathy Free
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Brad Fortune; Marilyn E. Schneck; Anthony J. Adams
Tags: diabetes mellitus, diabetic retinopathy, electroretinography, eye, retinal diseases
Investigative Ophthalmology & Visual Science October 1999, Vol.40, 2638-2651. doi:
Induction of Glutathione S-Transferase hGST 5.8 Is an Early Response to Oxidative Stress in RPE Cells Free
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Sharad S. Singhal; Bernard F. Godley; Animesh Chandra; Utpal Pandya; Gui-Fang Jin; Manjit K. Saini; Sanjay Awasthi; Yogesh C. Awasthi
Tags: enzymes, glutathione, isoenzymes, oxidative stress, retinal pigment cell
Investigative Ophthalmology & Visual Science October 1999, Vol.40, 2652-2659. doi:
Inhibition of Caspase Activity in Retinal Cell Apoptosis Induced by Various Stimuli In Vitro Free
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Gülgün Tezel; Martin B. Wax
Tags: apoptosis, caspase-3, caspases, antibodies, caspase inhibitors
Investigative Ophthalmology & Visual Science October 1999, Vol.40, 2660-2667. doi:
Intrafamilial Variation of Phenotype in Stargardt Macular Dystrophy–Fundus Flavimaculatus Free
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Noemi Lois; Graham E. Holder; Frederick W. Fitzke; Catherine Plant; Alan C. Bird
Tags: age of onset, family, macular dystrophy, phenotype, relationship - sibling
Investigative Ophthalmology & Visual Science October 1999, Vol.40, 2668-2675. doi:
Age-Dependent Variation in Metalloproteinase Activity of Isolated Human Bruch’s Membrane and Choroid Free
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Li Guo; Ali A. Hussain; G. Astrid Limb; John Marshall
Tags: bruch's basal membrane, choroid, gelatinase a, gelatinases, matrix metalloproteinases
Investigative Ophthalmology & Visual Science October 1999, Vol.40, 2676-2682. doi:
Platelet-Derived Growth Factor Plays a Key Role in Proliferative Vitreoretinopathy Free
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Anthony Andrews; Egle Balciunaite; Fee Lai Leong; Michelle Tallquist; Philippe Soriano; Miguel Refojo; Andrius Kazlauskas
Tags: oryctolagus cuniculus, platelet-derived growth factor, vitreoretinopathy, proliferative, platelet-derived growth factor receptor
Investigative Ophthalmology & Visual Science October 1999, Vol.40, 2683-2689. doi:
Targeted Delivery of Anti–Angiogenic Agent TNP-470 Using Water-Soluble Polymer in the Treatment of Choroidal Neovascularization Free
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Tsutomu Yasukawa; Hideya Kimura; Yasuhiko Tabata; Hideki Miyamoto; Yoshihito Honda; Yoshito Ikada; Yuichiro Ogura
Tags: choroidal neovascularization, o-(chloroacetylcarbamoyl)fumagillol, water, polymers, angiogenesis
Investigative Ophthalmology & Visual Science October 1999, Vol.40, 2690-2696. doi:
A Novel ABCR Nonsense Mutation Responsible for Late-Onset Fundus Flavimaculatus Free
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Eric H. Souied; Dominique Ducroq; Jean–Michel Rozet; Sylvie Gerber; Isabelle Perrault; Margaret Sterkers; Nathanael Benhamou; Arnold Munnich; Gabriel Coscas; Gisèle Soubrane; Josseline Kaplan
Tags: mutation, nonsense, stargardt's disease, mutation, genes, heterozygote
Investigative Ophthalmology & Visual Science October 1999, Vol.40, 2740-2744. doi:
Blue-on-Yellow Perimetry in the Complete Type of Congenital Stationary Night Blindness Free
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Hiroko Terasaki; Yozo Miyake; Ryoji Nomura; Masayuki Horiguchi; Satoshi Suzuki; Mineo Kondo
Tags: night blindness, congenital stationary, perimetry, retinal cone, electroretinography
Investigative Ophthalmology & Visual Science October 1999, Vol.40, 2761-2764. doi:

Retinal Cell Biology

Apoptotic Retinal Neuronal Death by Ischemia–Reperfusion Is Executed by Two Distinct Caspase Family Proteases Free
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Naomichi Katai; Nagahisa Yoshimura
Tags: caspase-1, caspase-3, caspases, endopeptidases, ischemia
Investigative Ophthalmology & Visual Science October 1999, Vol.40, 2697-2705. doi:
Cell-Specific Expression of Tubby Gene Family Members (tub, Tulp1, 2, and 3) in the Retina Free
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Sakae Ikeda; Wei He; Akihiro Ikeda; Jürgen K. Naggert; Michael A. North; Patsy M. Nishina
Tags: family, genes, in situ hybridization, mice, proteins
Investigative Ophthalmology & Visual Science October 1999, Vol.40, 2706-2712. doi:
A Distinct Integrin-Mediated Phagocytic Pathway for Extracellular Matrix Remodeling by RPE Cells Free
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Ming Wei Zhao; Man Lin Jin; Shikun He; Christine Spee; Stephen J. Ryan; David R. Hinton
Tags: fibronectins, integrins, phagocytosis, retinal pigment cell, extracellular matrix
Investigative Ophthalmology & Visual Science October 1999, Vol.40, 2713-2723. doi:
Glial Cell Line–Derived Neurotrophic Factor Induces Histologic and Functional Protection of Rod Photoreceptors in the rd/rd Mouse Free
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Maria Frasson; Serge Picaud; Thierry Léveillard; Manuel Simonutti; Saddek Mohand–Said; Henri Dreyfus; David Hicks; José Sahel
Tags: glial cell-line derived neurotrophic factor, mice, rod photoreceptors, retina
Investigative Ophthalmology & Visual Science October 1999, Vol.40, 2724-2734. doi:

Erratum

Erratum Free
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Investigative Ophthalmology & Visual Science October 1999, Vol.40, 2470. doi:
Copyright © 2025 Association for Research in Vision and Ophthalmology.
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