Volume 44 Issue 8 | IOVS

Idiopathic and Radiation-Induced Ocular Telangiectasia: The Involvement of the ATM Gene Free

Martine Mauget-Faÿsse; Michèle Vuillaume; Maddalena Quaranta; Norman Moullan; Sandra Angèle; Marlin D. Friesen; Janet Hall

Tags: atm gene, radiation, telangiectasis

Investigative Ophthalmology & Visual Science August 2003, Vol.44, 3257-3262. doi:https://doi.org/10.1167/iovs.02-1269

Human Lens Thioredoxin: Molecular Cloning and Functional Characterization Free

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Svitlana Yegorova; Aimin Liu; Marjorie F. Lou

Tags: lens, crystalline, molecular cloning, proteins, suidae, thioredoxin

Investigative Ophthalmology & Visual Science August 2003, Vol.44, 3263-3271. doi:https://doi.org/10.1167/iovs.02-1322

Mutations in the CHST6 Gene in Patients with Macular Corneal Dystrophy: Immunohistochemical Evidence of Heterogeneity Free

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Nobuko Iida-Hasegawa; Atushi Furuhata; Hiroo Hayatsu; Akira Murakami; Keiko Fujiki; Kiyoo Nakayasu; Atsushi Kanai

Tags: cornea, genes, hereditary corneal dystrophy, heterogeneity, mutation

Investigative Ophthalmology & Visual Science August 2003, Vol.44, 3272-3277. doi:https://doi.org/10.1167/iovs.02-0910

Clinical and Epidemiologic Research

How Sensitive to Clinical Change are ETDRS logMAR Visual Acuity Measurements? Free

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Daniel A. Rosser; Simon N. Cousens; Ian E. Murdoch; Fred W. Fitzke; David A. H. Laidlaw

Tags: specificity of diagnostic test, visual acuity

Investigative Ophthalmology & Visual Science August 2003, Vol.44, 3278-3281. doi:https://doi.org/10.1167/iovs.02-1100

Uveal Melanoma Survival in Sweden from 1960 to 1998 Free

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Louise Bergman; Stefan Seregard; Bo Nilsson; Göran Lundell; Ulrik Ringborg; Boel Ragnarsson-Olding

Tags: uveal melanoma, mortality

Investigative Ophthalmology & Visual Science August 2003, Vol.44, 3282-3287. doi:https://doi.org/10.1167/iovs.03-0081

Evaluation of Sampling Strategies for Modeling Survival of Uveal Malignant Melanoma Free

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Tero Kivelä; Patricia M. Grambsch

Tags: cox proportional hazards models, malignant melanoma of uveal tract, uveal melanoma, hypothesis testing, mortality

Investigative Ophthalmology & Visual Science August 2003, Vol.44, 3288-3293. doi:https://doi.org/10.1167/iovs.02-1328

Repeatability of ETDRS Visual Acuity in Children Free

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Ruth E. Manny; Mohamed Hussein; Jane Gwiazda; Wendy Marsh-Tootle

Tags: child, eye, visual acuity

Investigative Ophthalmology & Visual Science August 2003, Vol.44, 3294-3300. doi:https://doi.org/10.1167/iovs.02-1199

Cornea

A Comparison of Biological Coatings for the Promotion of Corneal Epithelialization of Synthetic Surface In Vivo Free

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Deborah F. Sweeney; Ruo Zhong Xie; Margaret D. M. Evans; Antti Vannas; Simon D. Tout; Hans J. Griesser; Graham Johnson; Jack G. Steele

Tags: collagen, cornea, epithelialization, epithelium, implants

Investigative Ophthalmology & Visual Science August 2003, Vol.44, 3301-3309. doi:https://doi.org/10.1167/iovs.02-0561

Mutation Analysis of the Carbohydrate Sulfotransferase Gene in Vietnamese with Macular Corneal Dystrophy Free

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Nguyen Thanh Ha; Hoang Minh Chau; Le Xuan Cung; Ton Kim Thanh; Keiko Fujiki; Akira Murakami; Yoshimune Hiratsuka; Atsushi Kanai

Tags: carbohydrates, genes, hereditary corneal dystrophy, mutation analysis, sulfotransferase

Investigative Ophthalmology & Visual Science August 2003, Vol.44, 3310-3316. doi:https://doi.org/10.1167/iovs.03-0031

Production of Fibronectin and Tenascin Isoforms and Their Role in the Adhesion of Human Immortalized Corneal Epithelial Cells Free

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Sissi Filenius; Timo Tervo; Ismo Virtanen

Tags: adhesions, corneal epithelial cells, fibronectins, protein isoforms, tenascin

Investigative Ophthalmology & Visual Science August 2003, Vol.44, 3317-3325. doi:https://doi.org/10.1167/iovs.02-1146

Predicting Endothelial Cell Loss and Long-Term Corneal Graft Survival Free

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W. John Armitage; Andrew D. Dick; William M. Bourne

Tags: endothelial cells, keratoplasty, keratoplasty, penetrating

Investigative Ophthalmology & Visual Science August 2003, Vol.44, 3326-3331. doi:https://doi.org/10.1167/iovs.02-1255

Up-Regulation of Urokinase-Type Plasminogen Activator in Corneal Epithelial Cells Induced by Wounding Free

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Masanao Watanabe; Wataru Yano; Shoichi Kondo; Yukio Hattori; Naoyuki Yamada; Ryoji Yanai; Teruo Nishida

Tags: urokinase, oryctolagus cuniculus, corneal epithelial cells

Investigative Ophthalmology & Visual Science August 2003, Vol.44, 3332-3338. doi:https://doi.org/10.1167/iovs.02-1280

Serum Albumin in Mammalian Cornea: Implications for Clinical Application Free

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David W. Nees; Robert N. Fariss; Joram Piatigorsky

Tags: cornea, mammals, proteins, serum albumin, mice

Investigative Ophthalmology & Visual Science August 2003, Vol.44, 3339-3345. doi:https://doi.org/10.1167/iovs.02-1161

Rat Corneal Allograft Survival Prolonged by the Superantigen Staphylococcal Enterotoxin B Free

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Zhiqiang Pan; Yu Chen; Wenhua Zhang; Ying Jie; Na Li; Yuying Wu

Tags: allografting, cornea, keratoplasty, staphylococcal enterotoxin b, superantigens

Investigative Ophthalmology & Visual Science August 2003, Vol.44, 3346-3351. doi:https://doi.org/10.1167/iovs.02-0845

Presence and Localization of Neurotrophins and Neurotrophin Receptors in Rat Lacrimal Gland Free

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Emiliano Ghinelli; Jenny Johansson; José D. Ríos; Li-Li Chen; Driss Zoukhri; Robin R. Hodges; Darlene A. Dartt

Tags: brain-derived neurotrophic factor, lacrimal gland, nerve growth factors, neurotrophic tyrosine kinase receptor type 2, neurotrophic tyrosine kinase receptor type 3

Investigative Ophthalmology & Visual Science August 2003, Vol.44, 3352-3357. doi:https://doi.org/10.1167/iovs.03-0037

Eye Movements, Strabismus, Amblyopia and Neuro-ophthalmology

Maldevelopment of Convergence Eye Movements in Macaque Monkeys with Small- and Large-Angle Infantile Esotropia Free

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Lawrence Tychsen; Colin Scott

Tags: cercopithecidae, eye movement, esotropia, eye, infantile esotropia

Investigative Ophthalmology & Visual Science August 2003, Vol.44, 3358-3368. doi:https://doi.org/10.1167/iovs.02-0698

Glaucoma

Optical Tomography–Measured Retinal Nerve Fiber Layer Thickness in Normal Latinos Free

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Rohit Varma; Sheila Bazzaz; Mei Lai

Tags: hispanics or latinos, optics, retinal nerve fiber layer, tomography, eye

Investigative Ophthalmology & Visual Science August 2003, Vol.44, 3369-3373. doi:https://doi.org/10.1167/iovs.02-0975

Antigenic Specificity of Immunoprotective Therapeutic Vaccination for Glaucoma Free

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Sharon Bakalash; Anat Kessler; Tal Mizrahi; Robert Nussenblatt; Michal Schwartz

Tags: antigens, eye, glaucoma, intraocular pressure, peptides

Investigative Ophthalmology & Visual Science August 2003, Vol.44, 3374-3381. doi:https://doi.org/10.1167/iovs.03-0080

Racial Differences in the Association between Optic Disc Topography and Early Glaucoma Free

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Christopher A. Girkin; Gerald McGwin, Jr; Sandre F. McNeal; Julio DeLeon-Ortega

Tags: glaucoma, optic disk, racial differences, african american, european continental ancestry group

Investigative Ophthalmology & Visual Science August 2003, Vol.44, 3382-3387. doi:https://doi.org/10.1167/iovs.02-0792

A Model to Study Differences between Primary and Secondary Degeneration of Retinal Ganglion Cells in Rats by Partial Optic Nerve Transection Free

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Hana Levkovitch-Verbin; Harry A. Quigley; Keith R. G. Martin; Donald J. Zack; Mary Ellen Pease; Danielle F. Valenta

Tags: axon, optic nerve, rats, retinal ganglion cells, wallerian degeneration

Investigative Ophthalmology & Visual Science August 2003, Vol.44, 3388-3393. doi:https://doi.org/10.1167/iovs.02-0646

Evaluation of Anti-TGF-β2 Antibody as a New Postoperative Anti-scarring Agent in Glaucoma Surgery Free

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Anna L. Mead; Tina T. L. Wong; M. Francesca Cordeiro; Ian K. Anderson; Peng T. Khaw

Tags: adaptive testing, antibodies, blister, cats, chloramphenicol o-acetyltransferase

Investigative Ophthalmology & Visual Science August 2003, Vol.44, 3394-3401. doi:https://doi.org/10.1167/iovs.02-0978

Immunology and Microbiology

The Critical Role of IFN-γ in Experimental Coronavirus Retinopathy Free

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John J. Hooks; Yun Wang; Barbara Detrick

Tags: coronavirus, mice, mice, inbred balb c, retina, retinal diseases

Investigative Ophthalmology & Visual Science August 2003, Vol.44, 3402-3408. doi:https://doi.org/10.1167/iovs.02-1106

Analysis of Pseudomonas aeruginosa Corneal Infection Using an Oligonucleotide Microarray Free

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Xi Huang; Linda D. Hazlett

Tags: cornea, corneal infections, mice, oligonucleotide arrays, pseudomonas aeruginosa

Investigative Ophthalmology & Visual Science August 2003, Vol.44, 3409-3416. doi:https://doi.org/10.1167/iovs.03-0162

Effects of IL-4 on Conjunctival Fibroblasts: Possible Role in Ocular Cicatricial Pemphigoid Free

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Mohammed S. Razzaque; Babar S. Ahmed; C. Stephen Foster; A. Razzaque Ahmed

Tags: conjunctiva, fibroblasts, interleukin-4, ocular cicatricial pemphigoid, macrophage colony-stimulating factor

Investigative Ophthalmology & Visual Science August 2003, Vol.44, 3417-3423. doi:https://doi.org/10.1167/iovs.02-1084

Effects of Mannose on Acanthamoeba castellanii Proliferation and Cytolytic Ability to Corneal Epithelial Cells Free

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Michael Hurt; Jerry Niederkorn; Hassan Alizadeh

Tags: mannose, proteins, corneal epithelial cells, acanthamoeba castellanii, trophozoite

Investigative Ophthalmology & Visual Science August 2003, Vol.44, 3424-3431. doi:https://doi.org/10.1167/iovs.03-0019

Differential Regulation of ENA-78 and GCP-2 Gene Expression in Human Corneal Keratocytes and Epithelial Cells Free

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Rebecca A. Fillmore; Shannon E. Nelson; Robert N. Lausch; John E. Oakes

Tags: cornea, epithelial cells, gene expression, keratocytes, regulation

Investigative Ophthalmology & Visual Science August 2003, Vol.44, 3432-3437. doi:https://doi.org/10.1167/iovs.03-0095

Lens

Mechanisms and Physiological Significance of the Transport of the Glutathione Conjugate of 4-Hydroxynonenal in Human Lens Epithelial Cells Free

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Rajendra Sharma; Yusong Yang; Abha Sharma; Seema Dwivedi; Vsevolod L. Popov; Paul J. Boor; Sharad S. Singhal; Sanjay Awasthi; Yogesh C. Awasthi

Tags: biological transport, epithelial cells, glutathione, immunoglobulin g, lens, crystalline

Investigative Ophthalmology & Visual Science August 2003, Vol.44, 3438-3449. doi:https://doi.org/10.1167/iovs.03-0051

A New Model of Posterior Capsule Opacification in Rodents Free

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Noemi Lois; Rosemary Dawson; Alastair D. McKinnon; John V. Forrester

Tags: after-cataract, eye, lens (device), lens, crystalline, rodentia

Investigative Ophthalmology & Visual Science August 2003, Vol.44, 3450-3457. doi:https://doi.org/10.1167/iovs.02-1293

Expression Patterns for Glucose Transporters GLUT1 and GLUT3 in the Normal Rat Lens and in Models of Diabetic Cataract Free

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B. Rachelle Merriman-Smith; Anatoly Krushinsky; Joerg Kistler; Paul J. Donaldson

Tags: glucose transporter, lens (device), lens, crystalline, diabetes mellitus, diabetic cataract

Investigative Ophthalmology & Visual Science August 2003, Vol.44, 3458-3466. doi:https://doi.org/10.1167/iovs.02-1235

The Effect of Up- and Downregulation of MnSOD Enzyme on Oxidative Stress in Human Lens Epithelial Cells Free

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Hironori Matsui; Li-Ren Lin; Ye-Shih Ho; Venkat N. Reddy

Tags: down-regulation, enzymes, epithelial cells, lens, crystalline, oxidative stress

Investigative Ophthalmology & Visual Science August 2003, Vol.44, 3467-3475. doi:https://doi.org/10.1167/iovs.02-0830

Lenticular Oxygen Toxicity Free

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Shlomit Schaal; Itzchak Beiran; Irit Rubinstein; Benjamin Miller; Ahuva Dovrat

Tags: lens (device), lens, crystalline, oxygen toxicity, oxygen, optics

Investigative Ophthalmology & Visual Science August 2003, Vol.44, 3476-3484. doi:https://doi.org/10.1167/iovs.03-0122

Physiology and Pharmacology

Expression of Matrix Metalloproteinases and Their Inhibitors in Human Trabecular Meshwork Cells Free

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Iok-Hou Pang; Peggy E. Hellberg; Debra L. Fleenor; Nasreen Jacobson; Abbot F. Clark

Tags: matrix metalloproteinases, trabecular meshwork, stromelysin 1, tissue-inhibitor of metalloproteinase-1, tissue inhibitor of metalloproteinases

Investigative Ophthalmology & Visual Science August 2003, Vol.44, 3485-3493. doi:https://doi.org/10.1167/iovs.02-0756

Involvement of AP-1 in Interleukin-1α–Stimulated MMP-3 Expression in Human Trabecular Meshwork Cells Free

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Debra L. Fleenor; Iok-Hou Pang; Abbot F. Clark

Tags: interleukins, stromelysin 1, transcription factor ap-1, trabecular meshwork

Investigative Ophthalmology & Visual Science August 2003, Vol.44, 3494-3501. doi:https://doi.org/10.1167/iovs.02-0757

Aqueous Outflow–Enhancing Effect of tert-Butylhydroquinone: Involvement of AP-1 Activation and MMP-3 Expression Free

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Iok-Hou Pang; Debra L. Fleenor; Peggy E. Hellberg; Karen Stropki; Mitchell D. McCartney; Abbot F. Clark

Tags: eye, stromelysin 1, transcription factor ap-1, perfusion, organ culture techniques

Investigative Ophthalmology & Visual Science August 2003, Vol.44, 3502-3510. doi:https://doi.org/10.1167/iovs.02-0758

Expression of the Inwardly Rectifying K⁺ Channel Kir2.1 in Native Bovine Corneal Endothelial Cells Free

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Dongli Yang; Donald K. MacCallum; Stephen A. Ernst; Bret A. Hughes

Tags: cattle, cornea, endothelial cells, membrane potentials, reverse transcriptase polymerase chain reaction

Investigative Ophthalmology & Visual Science August 2003, Vol.44, 3511-3519. doi:https://doi.org/10.1167/iovs.02-1306

Examination of Murine Tear Film Free

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Cuong H. Tran; Caroline Routledge; Julian Miller; Frances Miller; Stuart A. Hodson

Tags: tear film finding

Investigative Ophthalmology & Visual Science August 2003, Vol.44, 3520-3525. doi:https://doi.org/10.1167/iovs.03-0178

Retina

Transplantation of Syngeneic Schwann Cells to the Retina of the Rhodopsin Knockout (Rho^−/−) Mouse Free

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David J. Keegan; Paul Kenna; Marian M. Humphries; Peter Humphries; Daniel I. Flitcroft; Peter J. Coffey; Ray D. Lund; Jean M. Lawrence

Tags: mice, retina, rhodopsin, schwann cells, transplantation

Investigative Ophthalmology & Visual Science August 2003, Vol.44, 3526-3532. doi:https://doi.org/10.1167/iovs.02-0097

Thresholds for Activation of Rabbit Retinal Ganglion Cells with an Ultrafine, Extracellular Microelectrode Free

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Ralph J. Jensen; Joseph F. Rizzo, III; Ofer R. Ziv; Andrew Grumet; John Wyatt

Tags: axon, microelectrodes, oryctolagus cuniculus, polarity, retinal ganglion cells

Investigative Ophthalmology & Visual Science August 2003, Vol.44, 3533-3543. doi:https://doi.org/10.1167/iovs.02-1041

Pattern ERG Correlates of Abnormal Fundus Autofluorescence in Patients with Retinitis Pigmentosa and Normal Visual Acuity Free

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Anthony G. Robson; Ahmed El-Amir; Claire Bailey; Catherine A. Egan; Frederick W. Fitzke; Andrew R. Webster; Alan C. Bird; Graham E. Holder

Tags: electroretinography, fundus autofluorescence imaging, retinitis pigmentosa, visual acuity, autofluorescence

Investigative Ophthalmology & Visual Science August 2003, Vol.44, 3544-3550. doi:https://doi.org/10.1167/iovs.02-1278

Specificity of Subnormal ΔPo ₂ for Retinal Neovascularization in Experimental Retinopathy of Prematurity Free

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Wei Zhang; Yasuki Ito; Emily Berlin; Robin Roberts; Hongmei Luan; Bruce A. Berkowitz

Tags: functional magnetic resonance imaging, inspiration, oxygen, retinal neovascularization, retinopathy of prematurity

Investigative Ophthalmology & Visual Science August 2003, Vol.44, 3551-3555. doi:https://doi.org/10.1167/iovs.03-0008

Alkylphosphocholines Inhibit Proliferation of Human Retinal Pigment Epithelial Cells Free

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Kirsten H. Eibl; Bernhard Banas; Carlo-L. Schoenfeld; Christian A. May; Aljoscha S. Neubauer; Siegfried Priglinger; Anselm Kampik; Ulrich Welge-Lussen

Tags: atrial premature complexes, retinal pigment cell, collagen

Investigative Ophthalmology & Visual Science August 2003, Vol.44, 3556-3561. doi:https://doi.org/10.1167/iovs.02-1172

Ocular Drug Delivery Targeting the Retina and Retinal Pigment Epithelium Using Polylactide Nanoparticles Free

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Jean-Louis Bourges; Sandrine E. Gautier; Florence Delie; Riad A. Bejjani; Jean-Claude Jeanny; Robert Gurny; David BenEzra; Francine F. Behar-Cohen

Tags: drug delivery systems, immunohistochemistry, microscopy, confocal, nanoparticles, polylactide

Investigative Ophthalmology & Visual Science August 2003, Vol.44, 3562-3569. doi:https://doi.org/10.1167/iovs.02-1068

Late-Onset Autosomal Dominant Macular Dystrophy with Choroidal Neovascularization and Nonexudative Maculopathy Associated with Mutation in the RDS Gene Free

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Shahrokh C. Khani; Athanasios J. Karoukis; Joyce E. Young; Rajesh Ambasudhan; Tracy Burch; Richard Stockton; Richard Alan Lewis; Lori S. Sullivan; Stephen P. Daiger; Elias Reichel; Radha Ayyagari

Tags: choroidal neovascularization, genes, macular disorders, macular dystrophy, mutation

Investigative Ophthalmology & Visual Science August 2003, Vol.44, 3570-3577. doi:https://doi.org/10.1167/iovs.02-1287

Macrophage Depletion Inhibits Experimental Choroidal Neovascularization Free

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Eiji Sakurai; Akshay Anand; Balamurali K. Ambati; Nico van Rooijen; Jayakrishna Ambati

Tags: choroidal neovascularization, macrophages, laser injuries, lip, lasers

Investigative Ophthalmology & Visual Science August 2003, Vol.44, 3578-3585. doi:https://doi.org/10.1167/iovs.03-0097

Macrophage Depletion Diminishes Lesion Size and Severity in Experimental Choroidal Neovascularization Free

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Diego G. Espinosa-Heidmann; Ivan J. Suner; Eleut P. Hernandez; Dagoberto Monroy; Karl G. Csaky; Scott W. Cousins

Tags: choroidal neovascularization, macrophages, mice, lip, monocytes

Investigative Ophthalmology & Visual Science August 2003, Vol.44, 3586-3592. doi:https://doi.org/10.1167/iovs.03-0038

De Novo Mutation in the RP1 Gene (Arg677ter) Associated with Retinitis Pigmentosa Free

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Sharon B. Schwartz; Tomas S. Aleman; Artur V. Cideciyan; Anand Swaroop; Samuel G. Jacobson; Edwin M. Stone

Tags: de novo mutation, genes, mutation, retinitis pigmentosa, proband

Investigative Ophthalmology & Visual Science August 2003, Vol.44, 3593-3597. doi:https://doi.org/10.1167/iovs.03-0155

Retinal Cell Biology

Proapoptotic Bcl-2 Family Members, Bax and Bak, Are Essential for Developmental Photoreceptor Apoptosis Free

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Paul Hahn; Tullia Lindsten; Gui-Shuang Ying; Jean Bennett; Ann H. Milam; Craig B. Thompson; Joshua L. Dunaief

Tags: apoptosis, bcl-2 gene family, photoreceptors, retina, mice

Investigative Ophthalmology & Visual Science August 2003, Vol.44, 3598-3605. doi:https://doi.org/10.1167/iovs.02-1113

GFAP Promoter Drives Müller Cell–Specific Expression in Transgenic Mice Free

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Milena Kuzmanovic; V. Joseph Dudley; Vijay P. Sarthy

Tags: glial fibrillary acidic protein, mice, transgenic, ciliary neurotrophic factor, retina, mice

Investigative Ophthalmology & Visual Science August 2003, Vol.44, 3606-3613. doi:https://doi.org/10.1167/iovs.02-1265

Disruption of Kinesin II Function Using a Dominant Negative-Acting Transgene in Xenopus laevis Rods Results in Photoreceptor Degeneration Free

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Jennifer Lin-Jones; Ed Parker; Mike Wu; Barry E. Knox; Beth Burnside

Tags: animals, transgenic, kinesin, photoreceptors, rod photoreceptors, tissue degeneration

Investigative Ophthalmology & Visual Science August 2003, Vol.44, 3614-3621. doi:https://doi.org/10.1167/iovs.03-0164

Expression and Localization of Bestrophin during Normal Mouse Development Free

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Benjamin Bakall; Lihua Y. Marmorstein; George Hoppe; Neal S. Peachey; Claes Wadelius; Alan D. Marmorstein

Tags: mice, proteins, polymerase chain reaction, electroretinography, rna, messenger

Investigative Ophthalmology & Visual Science August 2003, Vol.44, 3622-3628. doi:https://doi.org/10.1167/iovs.03-0030

Comparative Proteome Analysis of Native Differentiated and Cultured Dedifferentiated Human RPE Cells Free

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Claudia S. Alge; Sabine Suppmann; Siegfried G. Priglinger; Aljoscha S. Neubauer; Christian A. May; Stefanie Hauck; Ulrich Welge-Lussen; Marius Ueffing; Anselm Kampik

Tags: proteins, proteome, retinal pigment cell, gel

Investigative Ophthalmology & Visual Science August 2003, Vol.44, 3629-3641. doi:https://doi.org/10.1167/iovs.02-1225

Cloning, Mapping, and Retinal Expression of the Canine Ciliary Neurotrophic Factor Receptor α (CNTFRα) Free

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William A. Beltran; Qi Zhang; James W. Kijas; Danian Gu; Hermann Rohrer; Julie A. Jordan; Gustavo D. Aguirre

Tags: ciliary neurotrophic factor receptors, cloning, dog, domestic, retina, dna, complementary

Investigative Ophthalmology & Visual Science August 2003, Vol.44, 3642-3649. doi:https://doi.org/10.1167/iovs.02-0763

Combretastatin A-4 Phosphate Suppresses Development and Induces Regression of Choroidal Neovascularization Free

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Hiroyuki Nambu; Rie Nambu; Michele Melia; Peter A. Campochiaro

Tags: choroidal neovascularization, phosphates, vascular endothelial growth factor a

Investigative Ophthalmology & Visual Science August 2003, Vol.44, 3650-3655. doi:https://doi.org/10.1167/iovs.02-0985

The Kinase Inhibitor PKC412 Suppresses Epiretinal Membrane Formation and Retinal Detachment in Mice with Proliferative Retinopathies Free

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Yoshitsugu Saishin; Yumiko Saishin; Kyoichi Takahashi; Man-Seong Seo; Michele Melia; Peter A. Campochiaro

Tags: epiretinal membrane, kinase inhibitors, mice, proliferative diabetic retinopathy, retinal detachment

Investigative Ophthalmology & Visual Science August 2003, Vol.44, 3656-3662. doi:https://doi.org/10.1167/iovs.02-1143

Proteins Modified by Malondialdehyde, 4-Hydroxynonenal, or Advanced Glycation End Products in Lipofuscin of Human Retinal Pigment Epithelium Free

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Florian Schutt; Marion Bergmann; Frank G. Holz; Jurgen Kopitz

Tags: glycosylation end products, advanced, lipofuscin, malondialdehyde, proteins, retinal pigment epithelium

Investigative Ophthalmology & Visual Science August 2003, Vol.44, 3663-3668. doi:https://doi.org/10.1167/iovs.03-0172

Novel Role for a Complement Regulatory Protein (CD46) in Retinal Pigment Epithelial Adhesion Free

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Barbara J. McLaughlin; Wei Fan; Jing Juan Zheng; Hui Cai; Lucian V. Del Priore; Nalini S. Bora; Henry J. Kaplan

Tags: adhesions, cd46 antigen, complement system proteins, regulatory protein, pigment

Investigative Ophthalmology & Visual Science August 2003, Vol.44, 3669-3674. doi:https://doi.org/10.1167/iovs.02-0813

Visual Neuroscience

Functional Damage to Inner and Outer Retinal Cells in Experimental Glaucoma Free

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Dorit Raz; Ido Perlman; Christine L. Percicot; George N. Lambrou; Ron Ofri

Tags: eye, glaucoma, gamma-aminobutyric acid, glycine

Investigative Ophthalmology & Visual Science August 2003, Vol.44, 3675-3684. doi:https://doi.org/10.1167/iovs.02-1236

Scotopic Electroretinogram in Term Infants Born of Mothers Supplemented with Docosahexaenoic Acid during Pregnancy Free

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Cari A. Malcolm; Ruth Hamilton; Daphne L. McCulloch; Colette Montgomery; Lawrence T. Weaver

Tags: electroretinography, infant, mothers, pregnancy, docosahexaenoic acids

Investigative Ophthalmology & Visual Science August 2003, Vol.44, 3685-3691. doi:https://doi.org/10.1167/iovs.02-0767

Visual Psychophysics and Physiological Optics

The Effects of Constant and Diurnal Illumination of the Pineal Gland and the Eyes on Ocular Growth in Chicks Free

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Tong Li; Howard C. Howland

Tags: eye, lighting, pineal body, rhythm

Investigative Ophthalmology & Visual Science August 2003, Vol.44, 3692-3697. doi:https://doi.org/10.1167/iovs.02-0990

The Role of Lenticular Senescence in Age-Related Color Vision Changes Free

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David Nguyen-Tri; Olga Overbury; Jocelyn Faubert

Tags: aging, color vision, luminance, motion, older adult

Investigative Ophthalmology & Visual Science August 2003, Vol.44, 3698-3704. doi:https://doi.org/10.1167/iovs.02-1191

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