Volume 57 Issue 2 | IOVS

Parapapillary Gamma Zone and Axial Elongation–Associated Optic Disc Rotation: The Beijing Eye Study Open Access

Jost B. Jonas; Ya Xing Wang; Qi Zhang; Yuan Yuan Fan; Liang Xu; Wen Bin Wei; Rahul A. Jonas

Tags: eye, optic disk, fovea centralis, bruch's basal membrane

Investigative Ophthalmology & Visual Science February 2016, Vol.57, 396-402. doi:https://doi.org/10.1167/iovs.15-18263

Targeting the Nrf2 Signaling Pathway in the Retina With a Gene-Delivered Secretable and Cell-Penetrating Peptide Open Access

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Cristhian J. Ildefonso; Henrique Jaime; Emily E. Brown; Ryo L. Iwata; Chulbul M. Ahmed; Michael T. Massengill; Manas R. Biswal; Shannon E. Boye; William W. Hauswirth; John D. Ash; Qiuhong Li; Alfred S. Lewin

Tags: genes, mice, peptides, retina, signal pathway

Investigative Ophthalmology & Visual Science February 2016, Vol.57, 372-386. doi:https://doi.org/10.1167/iovs.15-17703

Vascular Endothelial Growth Factor (VEGF) Concentration Is Underestimated by Enzyme-Linked Immunosorbent Assay in the Presence of Anti-VEGF Drugs Open Access

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Hidenori Takahashi; Yoko Nomura; Junko Nishida; Yujiro Fujino; Yasuo Yanagi; Hidetoshi Kawashima

Tags: enzyme-linked immunosorbent assay, mass or substance concentration per volume, vascular endothelial growth factor a, bevacizumab, ranibizumab

Investigative Ophthalmology & Visual Science February 2016, Vol.57, 462-466. doi:https://doi.org/10.1167/iovs.15-18245

Clinical and Epidemiologic Research

Association Between Serum Levels of Testosterone and Estradiol With Meibomian Gland Assessments in Postmenopausal Women Open Access

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Anna F. Ablamowicz; Jason J. Nichols; Kelly K. Nichols

Tags: estradiol, hormones, meibomian gland, postmenopause, testosterone

Investigative Ophthalmology & Visual Science February 2016, Vol.57, 295-300. doi:https://doi.org/10.1167/iovs.15-18158

Corneal Mechanical Thresholds Negatively Associate With Dry Eye and Ocular Pain Symptoms Open Access

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Oriel Spierer; Elizabeth R. Felix; Allison L. McClellan; Jean Marie Parel; Alex Gonzalez; William J. Feuer; Constantine D. Sarantopoulos; Roy C. Levitt; Klaus Ehrmann; Anat Galor

Tags: cornea, dry eye syndromes, ocular pain, signs and symptoms, pain threshold

Investigative Ophthalmology & Visual Science February 2016, Vol.57, 617-625. doi:https://doi.org/10.1167/iovs.15-18133

The Association Between Subretinal Drusenoid Deposits in Older Adults in Normal Macular Health and Incident Age-Related Macular Degeneration Open Access

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Carrie Huisingh; Gerald McGwin, Jr; David Neely; Anna Zarubina; Mark Clark; Yuhua Zhang; Christine A. Curcio; Cynthia Owsley

Tags: age-related macular degeneration, digestive tract decontamination, eye, health, older adult

Investigative Ophthalmology & Visual Science February 2016, Vol.57, 739-745. doi:https://doi.org/10.1167/iovs.15-18316

Cornea

Predicative Factors for Corneal Endothelial Cell Migration Open Access

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Yu Qiang Soh; Gary Peh; Benjamin Lawrence George; Xin Yi Seah; Nishal Kishinchand Primalani; Khadijah Adnan; Jodhbir Singh Mehta

Tags: cornea, endothelial cells, endothelium, wounds and injuries, chronic exertional compartment syndrome

Investigative Ophthalmology & Visual Science February 2016, Vol.57, 338-348. doi:https://doi.org/10.1167/iovs.15-18300

APR-246/PRIMA-1^Met Inhibits and Reverses Squamous Metaplasia in Human Conjunctival Epithelium Open Access

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Jing Li; Cheng Li; Guoliang Wang; Zhen Liu; Pei Chen; Qichen Yang; Nuo Dong; Huping Wu; Zuguo Liu; Wei Li

Tags: conjunctiva, conjunctival epithelium, metaplasia, prima trial, epithelium

Investigative Ophthalmology & Visual Science February 2016, Vol.57, 444-452. doi:https://doi.org/10.1167/iovs.15-17519

All-Optical Method to Assess Stromal Concentration of Riboflavin in Conventional and Accelerated UV-A Irradiation of the Human Cornea Open Access

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Giuseppe Lombardo; Norberto Liborio Micali; Valentina Villari; Sebastiano Serrao; Marco Lombardo

Tags: cornea, mass or substance concentration per volume, optics, riboflavin, ultraviolet a radiation

Investigative Ophthalmology & Visual Science February 2016, Vol.57, 476-483. doi:https://doi.org/10.1167/iovs.15-18651

Glycerol Monolaurate Inhibits Lipase Production by Clinical Ocular Isolates Without Affecting Bacterial Cell Viability Open Access

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Judith Louise Flanagan; Neeta Khandekar; Hua Zhu; Keizo Watanabe; Maria Markoulli; John Terence Flanagan; Eric Papas

Tags: lipase, glyceryl monolaurate

Investigative Ophthalmology & Visual Science February 2016, Vol.57, 544-550. doi:https://doi.org/10.1167/iovs.15-17180

Species Cross-Reactivity of Antibodies Used to Treat Ophthalmic Conditions Open Access

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Yazad Irani; Pierre Scotney; Andrew Nash; Keryn A. Williams

Tags: antibodies, bevacizumab, cross reactions, enzyme-linked immunosorbent assay, infliximab

Investigative Ophthalmology & Visual Science February 2016, Vol.57, 586-591. doi:https://doi.org/10.1167/iovs.15-18239

Iontophoresis Transcorneal Delivery Technique for Transepithelial Corneal Collagen Crosslinking With Riboflavin in a Rabbit Model Open Access

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Myriam Cassagne; Camille Laurent; Magda Rodrigues; Anne Galinier; Eberhard Spoerl; Stéphane D. Galiacy; Vincent Soler; Pierre Fournié; François Malecaze

Tags: cornea, corneal collagen cross-linking, iontophoresis, oryctolagus cuniculus, riboflavin

Investigative Ophthalmology & Visual Science February 2016, Vol.57, 594-603. doi:https://doi.org/10.1167/iovs.13-12595

Neuroanatomy and Neurochemistry of Mouse Cornea Open Access

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Jiucheng He; Haydee E. P. Bazan

Tags: calcitonin gene-related peptide, cornea, mice, neurons, antibodies

Investigative Ophthalmology & Visual Science February 2016, Vol.57, 664-674. doi:https://doi.org/10.1167/iovs.15-18019

Biomarkers in Ocular Chronic Graft Versus Host Disease: Tear Cytokine- and Chemokine-Based Predictive Model Open Access

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Lidia Cocho; Itziar Fernández; Margarita Calonge; Verónica Martínez; María J. González-García; Dolores Caballero; Lucía López-Corral; Carmen García-Vázquez; Lourdes Vázquez; Michael E. Stern; Amalia Enríquez-de-Salamanca

Tags: biological markers, chemokines, cytokine, graft-versus-host disease, chronic, molecule

Investigative Ophthalmology & Visual Science February 2016, Vol.57, 746-758. doi:https://doi.org/10.1167/iovs.15-18615

Eye Movements, Strabismus, Amblyopia and Neuro-ophthalmology

Palisade Endings Are a Constant Feature in the Extraocular Muscles of Frontal-Eyed, But Not Lateral-Eyed, Animals Open Access

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Roland Blumer; Barbara Maurer-Gesek; Bernhard Gesslbauer; Michael Blumer; Elisabeth Pechriggl; María A. Davis-López de Carrizosa; Anja K. Horn; Paul J. May; Johannes Streicher; Rosa R. de la Cruz; Ángel M. Pastor

Tags: adaptive testing, bungarotoxins, cats, cercopithecidae, mammals

Investigative Ophthalmology & Visual Science February 2016, Vol.57, 320-331. doi:https://doi.org/10.1167/iovs.15-18716

Peripapillary Retinal Nerve Fiber Layer Swelling Predicts Peripapillary Atrophy in a Primate Model of Nonarteritic Anterior Ischemic Optic Neuropathy Open Access

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Mary A. Johnson; Neil R. Miller; Theresa Nolan; Steven L. Bernstein

Tags: atrophy, edema, primates

Investigative Ophthalmology & Visual Science February 2016, Vol.57, 527-532. doi:https://doi.org/10.1167/iovs.15-17880

How Eye Dominance Strength Modulates the Influence of a Distractor on Saccade Accuracy Open Access

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Jérôme Tagu; Karine Doré-Mazars; Christelle Lemoine-Lardennois; Dorine Vergilino-Perez

Tags: ocular dominance, saccades

Investigative Ophthalmology & Visual Science February 2016, Vol.57, 534-543. doi:https://doi.org/10.1167/iovs.15-18428

Genetics

Autosomal Dominant Retinal Dystrophies Caused by a Founder Splice Site Mutation, c.828+3A>T, in PRPH2 and Protein Haplotypes in trans as Modifiers Open Access

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Suma P. Shankar; Dianna K. Hughbanks-Wheaton; David G. Birch; Lori S. Sullivan; Karen N. Conneely; Sara J. Bowne; Edwin M. Stone; Stephen P. Daiger

Tags: genes, haplotypes, phenotype, proteins, visual fields

Investigative Ophthalmology & Visual Science February 2016, Vol.57, 349-359. doi:https://doi.org/10.1167/iovs.15-16965

Glaucoma

Structure–Function Relationship in Glaucoma Patients With Parafoveal Versus Peripheral Nasal Scotoma Open Access

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Kyoung In Jung; Min Ku Kang; Jin A. Choi; Hye-Young Shin; Chan Kee Park

Tags: glaucoma, nose, parafoveal region, scotoma, shedler-westen assessment procedure–200

Investigative Ophthalmology & Visual Science February 2016, Vol.57, 420-428. doi:https://doi.org/10.1167/iovs.15-18256

The Characteristics of Lamina Cribrosa Defects in Myopic Eyes With and Without Open-Angle Glaucoma Open Access

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Jong Chul Han; Seok Ho Cho; Dae Yong Sohn; Changwon Kee

Tags: cribriform plate, eye, open-angle glaucoma, myopia, glaucoma

Investigative Ophthalmology & Visual Science February 2016, Vol.57, 486-494. doi:https://doi.org/10.1167/iovs.15-17722

Ocular Outcomes Comparison Between 14- and 70-Day Head-Down-Tilt Bed Rest Open Access

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Giovanni Taibbi; Ronita L. Cromwell; Susana B. Zanello; Patrice O. Yarbough; Robert J. Ploutz-Snyder; Bernard F. Godley; Gianmarco Vizzeri

Tags: bed rest, head-down tilt, intraocular pressure

Investigative Ophthalmology & Visual Science February 2016, Vol.57, 495-501. doi:https://doi.org/10.1167/iovs.15-18530

Between-Subject Variability in Healthy Eyes as a Primary Source of Structural–Functional Discordance in Patients With Glaucoma Open Access

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Bright S. Ashimatey; William H. Swanson

Tags: eye, glaucoma, retinal nerve fiber layer, perimetry, bland-altman plot

Investigative Ophthalmology & Visual Science February 2016, Vol.57, 502-507. doi:https://doi.org/10.1167/iovs.15-18633

Does the Location of Bruch's Membrane Opening Change Over Time? Longitudinal Analysis Using San Diego Automated Layer Segmentation Algorithm (SALSA) Open Access

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Akram Belghith; Christopher Bowd; Felipe A. Medeiros; Naama Hammel; Zhiyong Yang; Robert N. Weinreb; Linda M. Zangwill

Tags: bruch's basal membrane, eye, follow-up, glaucoma, optic disk

Investigative Ophthalmology & Visual Science February 2016, Vol.57, 675-682. doi:https://doi.org/10.1167/iovs.15-17671

Morphological Abnormalities of Schlemm's Canal in Primary Open-Angle Glaucoma From the Aspect of Aging Open Access

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Teruhiko Hamanaka; Akira Matsuda; Tetsuro Sakurai; Toshio Kumasaka

Tags: aging, open-angle glaucoma, schlemm's canal, thrombomodulin, eye

Investigative Ophthalmology & Visual Science February 2016, Vol.57, 692-706. doi:https://doi.org/10.1167/iovs.15-17127

Down-regulation of 14-3-3 Zeta Inhibits TGF-β1–Induced Actomyosin Contraction in Human Trabecular Meshwork Cells Through RhoA Signaling Pathway Open Access

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Yiming Ye; Yangfan Yang; Xiaoxiao Cai; Liling Liu; Kaili Wu; Minbin Yu

Tags: actomyosin, down-regulation, rhoa gtp-binding protein, signal pathway, signal transduction pathways

Investigative Ophthalmology & Visual Science February 2016, Vol.57, 719-730. doi:https://doi.org/10.1167/iovs.15-17438

Immunology and Microbiology

Clinical Manifestations and Outcome of Syphilitic Uveitis Open Access

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Jan G. Bollemeijer; Wietse G. Wieringa; Tom O. A. R. Missotten; Ina Meenken; Ninette H. ten Dam-van Loon; Aniki Rothova; Leonoor I. Los

Tags: signs and symptoms, syphilis, syphilitic uveitis, treatment outcome, uveitis

Investigative Ophthalmology & Visual Science February 2016, Vol.57, 404-411. doi:https://doi.org/10.1167/iovs.15-17906

Topical Application of Interleukin-28A Attenuates Allergic Conjunctivitis in an Ovalbumin-Induced Mouse Model Open Access

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Jianping Chen; Jing Zhang; Ruijuan Zhao; Jiayi Jin; Ying Yu; Weihua Li; Wencong Wang; Hongyan Zhou; Shao Bo Su

Tags: administration, topical, allergic conjunctivitis, cytokine, immunoglobulin e, interleukins

Investigative Ophthalmology & Visual Science February 2016, Vol.57, 604-610. doi:https://doi.org/10.1167/iovs.15-18457

Lens

Dlg-1 Interacts With and Regulates the Activities of Fibroblast Growth Factor Receptors and EphA2 in the Mouse Lens Open Access

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SungKyoung Lee; Shalini Shatadal; Anne E. Griep

Tags: fgfr2 gene, fibroblast growth factor receptors, lens (device), lens, crystalline, mice

Investigative Ophthalmology & Visual Science February 2016, Vol.57, 707-718. doi:https://doi.org/10.1167/iovs.15-17727

Multidisciplinary Ophthalmic Imaging

Two-Photon Autofluorescence Imaging Reveals Cellular Structures Throughout the Retina of the Living Primate Eye Open Access

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Robin Sharma; David R. Williams; Grazyna Palczewska; Krzysztof Palczewski; Jennifer J. Hunter

Tags: autofluorescence, diagnostic imaging, photons, retina, fluorescence

Investigative Ophthalmology & Visual Science February 2016, Vol.57, 632-646. doi:https://doi.org/10.1167/iovs.15-17961

In Vivo Two-Photon Fluorescence Kinetics of Primate Rods and Cones Open Access

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Robin Sharma; Christina Schwarz; David R. Williams; Grazyna Palczewska; Krzysztof Palczewski; Jennifer J. Hunter

Tags: diagnostic imaging, fluorescence, kinetics, photons, photoreceptors, vertebrate

Investigative Ophthalmology & Visual Science February 2016, Vol.57, 647-657. doi:https://doi.org/10.1167/iovs.15-17946

Physiology and Pharmacology

The Role of Sphingosine-1-Phosphate in Adipogenesis of Graves' Orbitopathy Open Access

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Sung Eun Kim; Joon H. Lee; Min Kyoung Chae; Eun Jig Lee; Jin Sook Yoon

Tags: fibroblasts, hydrogen peroxide, sphingosine-1-phosphate phosphatase, oxidative stress, rna, messenger

Investigative Ophthalmology & Visual Science February 2016, Vol.57, 301-311. doi:https://doi.org/10.1167/iovs.15-17863

Involvement of AMPA Receptor and Its Flip and Flop Isoforms in Retinal Ganglion Cell Death Following Oxygen/Glucose Deprivation Open Access

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Yong H. Park; Heather V. Broyles; Shaoqing He; Nolan R. McGrady; Linya Li; Thomas Yorio

Tags: ampa receptors, glucose, oxygen, protein isoforms, retinal ganglion cells

Investigative Ophthalmology & Visual Science February 2016, Vol.57, 508-526. doi:https://doi.org/10.1167/iovs.15-18481

Bimatoprost Increases Mechanosensitivity of Trigeminal Ganglion Neurons Innervating the Inner Walls of Rat Anterior Chambers via Activation of TRPA1 Open Access

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Yun Ling; Zhuangli Hu; Qingli Meng; Peng Fang; Haixia Liu

Tags: bimatoprost, neurons, trpa1, anterior chamber of eye, trigeminal ganglion

Investigative Ophthalmology & Visual Science February 2016, Vol.57, 567-576. doi:https://doi.org/10.1167/iovs.15-18108

Retina

Structure/Psychophysical Relationships in X-Linked Retinoschisis Open Access

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Lea D. Bennett; Yi-Zhong Wang; Martin Klein; Mark E. Pennesi; Thiran Jayasundera; David G. Birch

Tags: psychophysics, x-linked retinoschisis, perimetry, visual acuity, retina

Investigative Ophthalmology & Visual Science February 2016, Vol.57, 332-337. doi:https://doi.org/10.1167/iovs.15-18354

Local Modulation of Retinal Vein Tone Open Access

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Dao-Yi Yu; Er-Ning Su; Stephen J. Cringle; William H. Morgan; Ian L. McAllister; Paula K. Yu

Tags: central retinal vein, adenosine, endothelin-1

Investigative Ophthalmology & Visual Science February 2016, Vol.57, 412-419. doi:https://doi.org/10.1167/iovs.15-18358

(+)-Pentazocine Reduces NMDA-Induced Murine Retinal Ganglion Cell Death Through a σR1-Dependent Mechanism Open Access

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Jing Zhao; Barbara A. Mysona; Azam Qureshi; Lily Kim; Taylor Fields; Graydon B. Gonsalvez; Sylvia B. Smith; Kathryn E. Bollinger

Tags: mice, n-methylaspartate, pentazocine, toxic effect, injections

Investigative Ophthalmology & Visual Science February 2016, Vol.57, 453-461. doi:https://doi.org/10.1167/iovs.15-18565

Extrafoveal Cone Packing in Eyes With a History of Retinopathy of Prematurity Open Access

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Ramkumar Ramamirtham; James D. Akula; Garima Soni; Matthew J. Swanson; Jennifer N. Bush; Anne Moskowitz; Emily A. Swanson; Tara L. Favazza; Jena L. Tavormina; Mircea Mujat; R. Daniel Ferguson; Ronald M. Hansen; Anne B. Fulton

Tags: eye, medical history, retinal cone, retinopathy of prematurity

Investigative Ophthalmology & Visual Science February 2016, Vol.57, 467-475. doi:https://doi.org/10.1167/iovs.15-17783

Controlled Release of Dexamethasone From an Intravitreal Delivery System Using Porous Silicon Dioxide Open Access

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Huiyuan Hou; Chengyun Wang; Kaihui Nan; William R. Freeman; Michael J. Sailor; Lingyun Cheng

Tags: dexamethasone, oryctolagus cuniculus, silicon dioxide, vascular endothelial growth factor a, cell-derived microparticles

Investigative Ophthalmology & Visual Science February 2016, Vol.57, 557-566. doi:https://doi.org/10.1167/iovs.15-18559

The Evaluation of Diabetic Macular Ischemia Using Optical Coherence Tomography Angiography Open Access

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Patrick D. Bradley; Dawn A. Sim; Pearse A. Keane; João Cardoso; Rupesh Agrawal; Adnan Tufail; Catherine A. Egan

Tags: angiogram, diabetes mellitus, diabetic retinopathy, ischemia, optical coherence tomography

Investigative Ophthalmology & Visual Science February 2016, Vol.57, 626-631. doi:https://doi.org/10.1167/iovs.15-18034

Hypothermia Promotes Survival of Ischemic Retinal Ganglion Cells Open Access

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Katja Reinhard; Marion Mutter; Elisabeth Gustafsson; Leon Gustafsson; Martin Vaegler; Maximilian Schultheiss; Sebastian Müller; Efdal Yoeruek; Merle Schrader; Thomas A. Münch

Tags: ganglia, hypothermia, induced, hypothermia, natural, ischemia, retina

Investigative Ophthalmology & Visual Science February 2016, Vol.57, 658-663. doi:https://doi.org/10.1167/iovs.15-17751

Human Vision–Motivated Algorithm Allows Consistent Retinal Vessel Classification Based on Local Color Contrast for Advancing General Diagnostic Exams Open Access

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Iliya V. Ivanov; Martin A. Leitritz; Lars A. Norrenberg; Michael Völker; Marek Dynowski; Marius Ueffing; Johannes Dietter

Tags: color, retinal vessels, vision, pixel, datasets

Investigative Ophthalmology & Visual Science February 2016, Vol.57, 731-738. doi:https://doi.org/10.1167/iovs.15-17831

In Vivo Imaging of Fluorescent Probes Linked to Antibodies Against Human and Rat Vascular Endothelial Growth Factor Open Access

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Johanna H. Meyer; Alexander Cunea; Kai Licha; Pia Welker; Dagmar Sonntag-Bensch; Paul Wafula; Jens Dernedde; Rolf Fimmers; Frank G. Holz; Steffen Schmitz-Valckenberg

Tags: antibodies, bevacizumab, diagnostic imaging, fluorescent probes, lasers

Investigative Ophthalmology & Visual Science February 2016, Vol.57, 759-770. doi:https://doi.org/10.1167/iovs.15-18118

Retinal Cell Biology

Interleukin-17A Induces IL-1β Secretion From RPE Cells Via the NLRP3 Inflammasome Open Access

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Shujie Zhang; Ning Yu; Rong Zhang; Shenghai Zhang; Jihong Wu

Tags: bodily secretions, inflammasomes, interleukin-17, retinal pigment cell, interleukins

Investigative Ophthalmology & Visual Science February 2016, Vol.57, 312-319. doi:https://doi.org/10.1167/iovs.15-17578

N-Acetylcysteine Amide Protects Against Oxidative Stress–Induced Microparticle Release From Human Retinal Pigment Epithelial Cells Open Access

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Kyle A. Carver; Dongli Yang

Tags: acetylcysteine, amides, hydrogen peroxide, mucopolysaccharidoses, oxidative stress

Investigative Ophthalmology & Visual Science February 2016, Vol.57, 360-371. doi:https://doi.org/10.1167/iovs.15-17117

siRNA-Mediated Knockdown of the mTOR Inhibitor RTP801 Promotes Retinal Ganglion Cell Survival and Axon Elongation by Direct and Indirect Mechanisms Open Access

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Peter J. Morgan-Warren; Jenna O'Neill; Felicity de Cogan; Igor Spivak; Hagit Ashush; Hagar Kalinski; Zubair Ahmed; Martin Berry; Elena Feinstein; Robert A. H. Scott; Ann Logan

Tags: axon, mtor inhibitors, neurites, neuroglia, retinal ganglion cells

Investigative Ophthalmology & Visual Science February 2016, Vol.57, 429-443. doi:https://doi.org/10.1167/iovs.15-17511

MRI of Retinal Free Radical Production With Laminar Resolution In Vivo Open Access

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Bruce A. Berkowitz; Alfred S. Lewin; Manas R. Biswal; Bryce X. Bredell; Christopher Davis; Robin Roberts

Tags: free radicals, magnetic resonance imaging, mice

Investigative Ophthalmology & Visual Science February 2016, Vol.57, 577-585. doi:https://doi.org/10.1167/iovs.15-18972

Visual Psychophysics and Physiological Optics

Flicker Sensitivity in Normal Aging—Monocular Tests of Retinal Function at Photopic and Mesopic Light Levels Open Access

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Wei Bi; Hanna Gillespie-Gallery; Alison Binns; John L. Barbur

Tags: aging, photopsia

Investigative Ophthalmology & Visual Science February 2016, Vol.57, 387-395. doi:https://doi.org/10.1167/iovs.15-16481

Myopes Show Greater Visually Induced Postural Responses Than Emmetropes Open Access

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Diane N. Sayah; Kristin Asaad; Jean-Marie Hanssens; Guillaume Giraudet; Jocelyn Faubert

Tags: refractive errors, regulation of posture, postural instability

Investigative Ophthalmology & Visual Science February 2016, Vol.57, 551-556. doi:https://doi.org/10.1167/iovs.15-17478

SyntEyes: A Higher-Order Statistical Eye Model for Healthy Eyes Open Access

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Jos J. Rozema; Pablo Rodriguez; Rafael Navarro; Marie-José Tassignon

Tags: eye, cornea, lens, crystalline, verification

Investigative Ophthalmology & Visual Science February 2016, Vol.57, 683-691. doi:https://doi.org/10.1167/iovs.15-18067

Letters to the Editor

A Problem of Proportions in OCT-Based Morphometry and a Proposed Solution Open Access

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Ian A. Sigal; Joel S. Schuman; Hiroshi Ishikawa; Larry Kagemann; Gadi Wollstein

Tags: cribriform plate, optic disk, pixel, software, stretching exercises

Investigative Ophthalmology & Visual Science February 2016, Vol.57, 484-485. doi:https://doi.org/10.1167/iovs.15-18570

Choroidal Folds in Astronauts Open Access

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Thomas H. Mader; C. Robert Gibson; Andrew G. Lee

Tags: astronauts, choroidal fold

Investigative Ophthalmology & Visual Science February 2016, Vol.57, 592. doi:https://doi.org/10.1167/iovs.15-18720

Author Response: Choroidal Folds in Astronauts Open Access

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Patrick A. Sibony; Mark J. Kupersmith; Steven E. Feldon; Randy Kardon

Tags: astronauts, choroidal fold

Investigative Ophthalmology & Visual Science February 2016, Vol.57, 593. doi:https://doi.org/10.1167/iovs.15-18927

Contamination of Primary Human Corneal Epithelial Cells With an SV40-Transformed Human Corneal Epithelial Cell Line: A Lesson for Cell Biologists in Good Laboratory Practice Open Access

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Nick Di Girolamo; Sharron Chow; Alex Richardson; Denis Wakefield

Tags: corneal epithelial cells, simian virus 40

Investigative Ophthalmology & Visual Science February 2016, Vol.57, 611-616. doi:https://doi.org/10.1167/iovs.15-18783

Transforming Growth Factor Beta Switch in Aqueous Humor of Patients With Fuchs' Endothelial Corneal Dystrophy Open Access

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An-Katrien De Roo; Sofie Struyf; Beatrijs Foets; Joost J. van den Oord

Tags: aqueous humor, endothelium, hereditary corneal dystrophy, transforming growth factor beta

Investigative Ophthalmology & Visual Science February 2016, Vol.57, 771-772. doi:https://doi.org/10.1167/iovs.15-18768

Author Response: Transforming Growth Factor Beta Switch in Aqueous Humor of Patients With Fuchs' Endothelial Corneal Dystrophy Open Access

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Mario Matthaei; Johannes Gillessen; Philipp S. Muether; Robert Hoerster; Björn O. Bachmann; Arno Hueber; Claus Cursiefen; Ludwig M. Heindl

Tags: aqueous humor, endothelium, hereditary corneal dystrophy, transforming growth factor beta

Investigative Ophthalmology & Visual Science February 2016, Vol.57, 773. doi:https://doi.org/10.1167/iovs.15-19049

Erratum

Erratum Open Access

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Investigative Ophthalmology & Visual Science February 2016, Vol.57, 403. doi:https://doi.org/10.1167/iovs.02-0589a

Erratum Open Access

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Investigative Ophthalmology & Visual Science February 2016, Vol.57, 533. doi:https://doi.org/10.1167/iovs.15-17576a

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