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Anatomy and Pathology/Oncology

Murine Autoimmune Optic Neuritis Is Not Phenotypically Altered by the Retinal Degeneration 8 Mutation Open Access
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Aleksandar Stojic; Richard Fairless; Susanne C. Beck; Vithiyanjali Sothilingam; Petra Weissgerber; Ulrich Wissenbach; Valerie Gimmy; Mathias W. Seeliger; Veit Flockerzi; Ricarda Diem; Sarah K. Williams
Tags: mice, mutation, optic neuritis, retinal degeneration, autoimmunity
Investigative Ophthalmology & Visual Science January 2017, Vol.58, 318-328. doi:https://doi.org/10.1167/iovs.16-20419
Altered Anterior Segment Biometric Parameters in Mice Deficient in SPARC Open Access
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Henrietta Ho; Hla M. Htoon; Gary Hin-Fai Yam; Li Zhen Toh; Nyein Chan Lwin; Stephanie Chu; Ying Shi Lee; Tina T. Wong; Li-Fong Seet
Tags: anterior chamber of eye, biometry, mice, sparc study, immune reconstitution inflammatory syndrome
Investigative Ophthalmology & Visual Science January 2017, Vol.58, 386-393. doi:https://doi.org/10.1167/iovs.16-20261

Biochemistry and Molecular Biology

The Effect of Phospholipids on Tear Film Lipid Layer Surface Activity Open Access
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Antti H. Rantamäki; Juha M. Holopainen *
Tags: lipids, phospholipids, tear film finding, water
Investigative Ophthalmology & Visual Science January 2017, Vol.58, 149-154. doi:https://doi.org/10.1167/iovs.16-20468
HTRA1 and TGF-β1 Concentrations in the Aqueous Humor of Patients With Neovascular Age-Related Macular Degeneration Open Access
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Gian Marco Tosi; Elena Caldi; Giovanni Neri; Elisabetta Nuti; Davide Marigliani; Stefano Baiocchi; Claudio Traversi; Gabriele Cevenini; Antonio Tarantello; Fiorella Fusco; Federica Nardi; Maurizio Orlandini; Federico Galvagni
Tags: aqueous humor, exudative age-related macular degeneration, htra1 gene
Investigative Ophthalmology & Visual Science January 2017, Vol.58, 162-167. doi:https://doi.org/10.1167/iovs.16-20922
β2–Adrenergic Receptor Antagonism Attenuates CNV Through Inhibition of VEGF and IL-6 Expression Open Access
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Jeremy A. Lavine; Mitra Farnoodian; Shoujian Wang; Soesiawati R. Darjatmoko; Lynda S. Wright; David M. Gamm; Michael S. Ip; Christine M. Sorenson; Nader Sheibani
Tags: adrenergic receptor, choroidal neovascularization, interleukin-6, vascular endothelial growth factor a, retinal pigment cell
Investigative Ophthalmology & Visual Science January 2017, Vol.58, 299-308. doi:https://doi.org/10.1167/iovs.16-20204
Restoration of Mesenchymal RPE by Transcription Factor-Mediated Reprogramming Open Access
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Ying-Hsuan Shih; Monte J. Radeke; Carolyn M. Radeke; Pete J. Coffey
Investigative Ophthalmology & Visual Science January 2017, Vol.58, 430-441. doi:https://doi.org/10.1167/iovs.16-20018
Integrated Comparison of GWAS, Transcriptome, and Proteomics Studies Highlights Similarities in the Biological Basis of Animal and Human Myopia Open Access