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Anatomy and Pathology/Oncology

The Imbalance of Lymphocyte Subsets and Cytokines: Potential Immunologic Insights Into the Pathogenesis of Chronic Dacryocystitis Open Access
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Xiaoxuan Yang; Lizhen Wang; Lunhao Li; Zhang Yu; Caiwen Xiao
Tags: cytokine, dacryocystitis, imbalance, immunology, lymphocyte subset
Investigative Ophthalmology & Visual Science April 2018, Vol.59, 1802-1809. doi:https://doi.org/10.1167/iovs.17-23660

Biochemistry and Molecular Biology

Integrin-Linked Kinase Controls Choroidal Neovascularization by Recruitment of Endothelial Progenitor Cells Open Access
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Xiu-Mei Yang; Chun-Guang Duan; Jian Zhang; Xiao-Jie Qu; Yu-Sheng Wang
Tags: choroidal neovascularization, hypoxia, rna, small interfering, stromal cell-derived factor 1, phosphotransferases
Investigative Ophthalmology & Visual Science April 2018, Vol.59, 1779-1789. doi:https://doi.org/10.1167/iovs.17-22931
Retinoic Acid Maintains Function of Neural Crest–Derived Ocular and Craniofacial Structures in Adult Zebrafish Open Access
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Bahaar Chawla; William Swain; Antionette L. Williams; Brenda L. Bohnsack
Investigative Ophthalmology & Visual Science April 2018, Vol.59, 1924-1935. doi:https://doi.org/10.1167/iovs.17-22845
Age-Related Changes to Human Tear Composition Open Access
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Alessandra Micera; Antonio Di Zazzo; Graziana Esposito; Rosa Longo; William Foulsham; Roberto Sacco; Roberto Sgrulletta; Stefano Bonini
Tags: aging, enzyme-linked immunosorbent assay, interleukin-6, interleukin-8, proteins
Investigative Ophthalmology & Visual Science April 2018, Vol.59, 2024-2031. doi:https://doi.org/10.1167/iovs.17-23358
The Level of Inflammatory Tear Cytokines is Elevated in Congenital Aniridia and Associated with Meibomian Gland Dysfunction Open Access
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Erlend C. S. Landsend; Øygunn A. Utheim; Hilde R. Pedersen; Hans Christian D. Aass; Neil Lagali; Darlene A. Dartt; Rigmor C. Baraas; Tor P. Utheim
Tags: aniridia, cytokine, meibomian gland, pathophysiology, eye
Investigative Ophthalmology & Visual Science April 2018, Vol.59, 2197-2204. doi:https://doi.org/10.1167/iovs.18-24027

Clinical and Epidemiologic Research

Plasma Concentrations of Lutein and Zeaxanthin, Macular Pigment Optical Density, and Their Associations With Cognitive Performances Among Older Adults Open Access
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Soufiane Ajana; Daniela Weber; Catherine Helmer; Bénédicte M. Merle; Wolfgang Stuetz; Jean-François Dartigues; Marie-Bénédicte Rougier; Jean-François Korobelnik; Tilman Grune; Cécile Delcourt; Catherine Féart
Tags: cognition, lutein, macular pigment, older adult, optics
Investigative Ophthalmology & Visual Science April 2018, Vol.59, 1828-1835. doi:https://doi.org/10.1167/iovs.17-22656
The Economic Burden of Visual Impairment and Comorbid Fatigue: A Cost-of-Illness Study (From a Societal Perspective) Open Access
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Wouter Schakel; Hilde P. A. van der Aa; Christina Bode; Carel T. J. Hulshof; Ger H. M. B. van Rens; Ruth M. A. van Nispen
Tags: fatigue, visual impairment, comorbidity, economics, cost of illness
Investigative Ophthalmology & Visual Science April 2018, Vol.59, 1916-1923. doi:https://doi.org/10.1167/iovs.17-23224
Long Anterior Lens Zonules and Intraocular Pressure Open Access
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Daniel K. Roberts; Tricia L. Newman; Mary Flynn Roberts; Bruce A. Teitelbaum; Janis E. Winters
Tags: intraocular pressure, lens, crystalline, eye
Investigative Ophthalmology & Visual Science April 2018, Vol.59, 2015-2023. doi:https://doi.org/10.1167/iovs.17-23705
Direct and Indirect Associations Between Diabetes and Intraocular Pressure: The Singapore Epidemiology of Eye Diseases Study Open Access
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Xiao-Yang Luo; Nicholas Y. Q. Tan; Miao-Li Chee; Yuan Shi; Yih-Chung Tham; Tien Yin Wong; Jie Jin Wang; Ching-Yu Cheng
Tags: diabetes mellitus, diabetes mellitus, type 2, eye diseases, intraocular pressure, singapore
Investigative Ophthalmology & Visual Science April 2018, Vol.59, 2205-2211. doi:https://doi.org/10.1167/iovs.17-23013

Cornea

Mast Cells Initiate the Recruitment of Neutrophils Following Ocular Surface Injury Open Access
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Srikant K. Sahu; Sharad K. Mittal; William Foulsham; Mingshun Li; Virender S. Sangwan; Sunil K. Chauhan
Tags: cornea, mast cells, neutrophil infiltration, neutrophils, wounds and injuries
Investigative Ophthalmology & Visual Science April 2018, Vol.59, 1732-1740. doi:https://doi.org/10.1167/iovs.17-23398
High-Mobility Group Box 1 in Dry Eye Inflammation Open Access
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Carolina Lema; Rose Y. Reins; Rachel L. Redfern
Investigative Ophthalmology & Visual Science April 2018, Vol.59, 1741-1750. doi:https://doi.org/10.1167/iovs.17-23363
Refractive Correction and Biomechanical Strength Following SMILE With a 110- or 160-μm Cap Thickness, Evaluated Ex Vivo by Inflation Test Open Access
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Iben Bach Damgaard; Anders Ivarsen; Jesper Hjortdal
Tags: cornea, economic inflation, postoperative care, preoperative care
Investigative Ophthalmology & Visual Science April 2018, Vol.59, 1836-1843. doi:https://doi.org/10.1167/iovs.17-23675
Oculomotor Status, Binocular Vision, and Stereoacuity in a Series of Keratoconus Subjects Open Access
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Rosália M. S. Antunes-Foschini; Jean V. A. L. Coutinho; Eduardo M. Rocha; Harley E. A. Bicas
Tags: anisometropia, depth perception, eye, keratoconus, perception
Investigative Ophthalmology & Visual Science April 2018, Vol.59, 1869-1877. doi:https://doi.org/10.1167/iovs.17-23484
The Relationship of Lid Wiper Epitheliopathy to Ocular Surface Signs and Symptoms Open Access
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Wing Li; Thao N. Yeh; Tiana Leung; Tiffany Yuen; Mariel Lerma; Meng C. Lin
Tags: contact lenses, ocular signs and symptoms, signs and symptoms, questionnaires
Investigative Ophthalmology & Visual Science April 2018, Vol.59, 1878-1887. doi:https://doi.org/10.1167/iovs.17-23639
Repeat-Associated Non-ATG (RAN) Translation in Fuchs' Endothelial Corneal Dystrophy Open Access
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Elisabetta Soragni; Lina Petrosyan; Tommy A. Rinkoski; Eric D. Wieben; Keith H. Baratz; Michael P. Fautsch; Joel M. Gottesfeld
Tags: antibodies, cornea, endothelium, hereditary corneal dystrophy, peptides
Investigative Ophthalmology & Visual Science April 2018, Vol.59, 1888-1896. doi:https://doi.org/10.1167/iovs.17-23265
Alterations of Murine Subbasal Corneal Nerves After Environmental Dry Eye Stress Open Access
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Cem Simsek; Takashi Kojima; Murat Dogru; Kazuo Tsubota
Tags: cornea, dry eye syndromes, mice, neurons, stress
Investigative Ophthalmology & Visual Science April 2018, Vol.59, 1986-1995. doi:https://doi.org/10.1167/iovs.17-23743
The Effect of Denatured Lysozyme on Human Corneal Epithelial Cells Open Access
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David J. McCanna; Sarah Oh; Junghee Seo; Chantal Coles-Brennan; Zohra Fadli; Lakshman N. Subbaraman; Lyndon W. Jones
Tags: muramidase, cytokine
Investigative Ophthalmology & Visual Science April 2018, Vol.59, 2006-2014. doi:https://doi.org/10.1167/iovs.17-22260
Tetramethylpyrazine in a Murine Alkali-Burn Model Blocks NFκB/NRF-1/CXCR4-Signaling-Induced Corneal Neovascularization Open Access
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Mingjun Tang; Ying Yang; Jingzhi Yu; Jin Qiu; Pei Chen; Yihui Wu; Qiyun Wang; Zhuojun Xu; Jian Ge; Keming Yu; Jing Zhuang
Tags: alkalies, burns, cxcr4 receptors, mice, corneal neovascularization
Investigative Ophthalmology & Visual Science April 2018, Vol.59, 2133-2141. doi:https://doi.org/10.1167/iovs.17-23712

Eye Movements, Strabismus, Amblyopia and Neuro-ophthalmology

Reliability and Validity of Gaze-Dependent Functional Vision Space: A Novel Metric Quantifying Visual Function in Infantile Nystagmus Syndrome Open Access
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Tawna L. Roberts; Kristi N. Kester; Richard W. Hertle
Tags: gaze, pathologic nystagmus, reliability, syndrome, validity of results
Investigative Ophthalmology & Visual Science April 2018, Vol.59, 1760-1768. doi:https://doi.org/10.1167/iovs.17-23229
Stable Microsaccades and Microsaccade-Induced Global Alpha Band Phase Reset Across the Life Span Open Access
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Ying Gao; Carl Huber; Bernhard A. Sabel
Tags: electroencephalography, life span, isolated tumor cells, older adult
Investigative Ophthalmology & Visual Science April 2018, Vol.59, 2032-2041. doi:https://doi.org/10.1167/iovs.17-23039
Ganglion Cell Layer and Inner Plexiform Layer as Predictors of Vision Recovery in Ethambutol-Induced Optic Neuropathy: A Longitudinal OCT Analysis Open Access
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Ju-Yeun Lee; Jae Hwan Choi; Kyung-Ah Park; Sei Yeul Oh
Tags: ethambutol, ganglia, optic nerve disorders, recovery of function, vision
Investigative Ophthalmology & Visual Science April 2018, Vol.59, 2104-2109. doi:https://doi.org/10.1167/iovs.17-22988
Longitudinal Evaluation of Accommodation During Treatment for Unilateral Amblyopia Open Access
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Angela M. Chen; Vivian Manh; T. Rowan Candy
Tags: amblyopia, visual accommodation, eye
Investigative Ophthalmology & Visual Science April 2018, Vol.59, 2187-2196. doi:https://doi.org/10.1167/iovs.17-22990

Genetics

The MT-CO1 V83I Polymorphism is a Risk Factor for Primary Open-Angle Glaucoma in African American Men Open Access
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David W. Collins; Harini V. Gudiseva; Venkata R. M. Chavali; Benjamin Trachtman; Meera Ramakrishnan; William T. Merritt III; Maxwell Pistilli; Rebecca A. Rossi; Stephanie Blachon; Prithvi S. Sankar; Eydie Miller-Ellis; Amanda Lehman; Victoria Addis; Joan M. O'Brien
Tags: open-angle glaucoma, risk factors, polymorphism
Investigative Ophthalmology & Visual Science April 2018, Vol.59, 1751-1759. doi:https://doi.org/10.1167/iovs.17-23277

Glaucoma

Interaction Between Pilocarpine and Ripasudil on Intraocular Pressure, Pupil Diameter, and the Aqueous-Outflow Pathway Open Access
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Reiko Yamagishi-Kimura; Megumi Honjo; Takashi Komizo; Takashi Ono; Akiko Yagi; Jinhee Lee; Kazunori Miyata; Tomokazu Fujimoto; Toshihiro Inoue; Hidenobu Tanihara; Junko Nishida; Takatoshi Uchida; Yuka Araki; Makoto Aihara
Tags: pilocarpine, intraocular pressure, pupil
Investigative Ophthalmology & Visual Science April 2018, Vol.59, 1844-1854. doi:https://doi.org/10.1167/iovs.18-23900
Reduced Functional and Anatomic Interhemispheric Homotopic Connectivity in Primary Open-Angle Glaucoma: A Combined Resting State-fMRI and DTI Study Open Access
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Qian Wang; Weiwei Chen; Huaizhou Wang; Xun Zhang; Xiaoxia Qu; Ying Wang; Ting Li; Ningli Wang; Junfang Xian
Tags: functional magnetic resonance imaging, open-angle glaucoma
Investigative Ophthalmology & Visual Science April 2018, Vol.59, 1861-1868. doi:https://doi.org/10.1167/iovs.17-23291
Validating Variational Bayes Linear Regression Method With Multi-Central Datasets Open Access
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Hiroshi Murata; Linda M. Zangwill; Yuri Fujino; Masato Matsuura; Atsuya Miki; Kazunori Hirasawa; Masaki Tanito; Shiro Mizoue; Kazuhiko Mori; Katsuyoshi Suzuki; Takehiro Yamashita; Kenji Kashiwagi; Nobuyuki Shoji; Ryo Asaoka
Tags: datasets, linear regression
Investigative Ophthalmology & Visual Science April 2018, Vol.59, 1897-1904. doi:https://doi.org/10.1167/iovs.17-22907
Lysophosphatidic Acid Induces ECM Production via Activation of the Mechanosensitive YAP/TAZ Transcriptional Pathway in Trabecular Meshwork Cells Open Access
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Leona T. Y. Ho; Nikolai Skiba; Christoph Ullmer; Ponugoti Vasantha Rao
Tags: connective tissue growth factor, immunoblotting, muscle contraction, proteins, trabecular meshwork
Investigative Ophthalmology & Visual Science April 2018, Vol.59, 1969-1984. doi:https://doi.org/10.1167/iovs.17-23702
Deep-Layer Microvasculature Dropout by Optical Coherence Tomography Angiography and Microstructure of Parapapillary Atrophy Open Access
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Min Hee Suh; Linda M. Zangwill; Patricia Isabel C. Manalastas; Akram Belghith; Adeleh Yarmohammadi; Tadamichi Akagi; Alberto Diniz-Filho; Luke Saunders; Robert N. Weinreb
Tags: atrophy, microvascular network, angiogram, optical coherence tomography
Investigative Ophthalmology & Visual Science April 2018, Vol.59, 1996-2005. doi:https://doi.org/10.1167/iovs.17-23046
Response of the Retinal Nerve Fiber Layer Reflectance and Thickness to Optic Nerve Crush Open Access
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Xiang-Run Huang; Wei Kong; Jianzhong Qiao
Tags: optic nerve, retina
Investigative Ophthalmology & Visual Science April 2018, Vol.59, 2094-2103. doi:https://doi.org/10.1167/iovs.17-23148
BMP and Activin Membrane Bound Inhibitor Regulates the Extracellular Matrix in the Trabecular Meshwork Open Access
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Humberto Hernandez; J. Cameron Millar; Stacy M. Curry; Abbot F. Clark; Colleen M. McDowell
Tags: activins, extracellular matrix, mice, tissue membrane, trabecular meshwork
Investigative Ophthalmology & Visual Science April 2018, Vol.59, 2154-2166. doi:https://doi.org/10.1167/iovs.17-23282

Immunology and Microbiology

Natural Killer Cell Inhibition by HLA-E Molecules on Induced Pluripotent Stem Cell–Derived Retinal Pigment Epithelial Cells Open Access
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Sunao Sugita; Kenichi Makabe; Yuko Iwasaki; Shota Fujii; Masayo Takahashi
Tags: human leukocyte antigens, idiopathic pneumonia syndrome, natural killer cells, retinal pigment cell, molecule
Investigative Ophthalmology & Visual Science April 2018, Vol.59, 1719-1731. doi:https://doi.org/10.1167/iovs.17-22703

Lens

Temporary Piggyback Intraocular Lens Implantation Versus Single Intraocular Lens Implantation in Congenital Cataracts: Long-Term Clinical Outcomes Open Access
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Sungsoon Hwang; Dong Hui Lim; Soomin Lee; Daye Diana Choi; Eui-Sang Chung; Tae-Young Chung
Tags: congenital cataract, intraocular lens implantation procedure, surgical procedures, operative, treatment outcome, implantation procedure
Investigative Ophthalmology & Visual Science April 2018, Vol.59, 1822-1827. doi:https://doi.org/10.1167/iovs.17-23684
Pharmacokinetics of Caffeine in the Lens Capsule/Epithelium After Peroral Intake: A Pilot Randomized Controlled Study Open Access
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Martin Kronschläger; Thomas Stimpfl; Manuel Ruiß; Nino Hirnschall; Christoph Leisser; Oliver Findl
Tags: caffeine, epithelium, lens (device), lens capsule, crystalline, lens, crystalline
Investigative Ophthalmology & Visual Science April 2018, Vol.59, 1855-1860. doi:https://doi.org/10.1167/iovs.18-23963

Multidisciplinary Ophthalmic Imaging

Multispectral Pattern Recognition Reveals a Diversity of Clinical Signs in Intermediate Age-Related Macular Degeneration Open Access
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Angelica Ly; Lisa Nivison-Smith; Nagi Assaad; Michael Kalloniatis
Tags: age-related macular degeneration, eye, pattern recognition, drusen, diagnostic imaging
Investigative Ophthalmology & Visual Science April 2018, Vol.59, 1790-1799. doi:https://doi.org/10.1167/iovs.17-23076
Retinal Oxygen Delivery and Metabolism in Healthy and Sickle Cell Retinopathy Subjects Open Access
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Mahnaz Shahidi; Anthony E. Felder; Ou Tan; Norman P. Blair; David Huang
Tags: metabolism, oxygen, oxygen delivery, sickle cell retinopathy
Investigative Ophthalmology & Visual Science April 2018, Vol.59, 1905-1909. doi:https://doi.org/10.1167/iovs.17-23647
In Vivo Characterization of Spontaneous Retinal Neovascularization in the Mouse Eye by Multifunctional Optical Coherence Tomography Open Access
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Marco Augustin; Matthias Wechdorn; Ulrike Pfeiffenberger; Tanja Himmel; Stanislava Fialová; René M. Werkmeister; Christoph K. Hitzenberger; Martin Glösmann; Bernhard Baumann
Tags: eye, mice, neovascularization, pathologic, optical coherence tomography, retinal neovascularization
Investigative Ophthalmology & Visual Science April 2018, Vol.59, 2054-2068. doi:https://doi.org/10.1167/iovs.17-23208

Physiology and Pharmacology

A Novel Selective Soluble Guanylate Cyclase Activator, MGV354, Lowers Intraocular Pressure in Preclinical Models, Following Topical Ocular Dosing Open Access
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Ganesh Prasanna; Luciana Ferrara; Christopher Adams; Takeru Ehara; Byron Li; Louis Yang; Chuanxi Xiang; Christopher Thow Hing Ng; Sean Kim; Christopher Towler; Todd Topley; Cale McAllister; Malay Ghosh; Ronald Newton; Rebecca Stacy; Dennis S. Rice; Muneto Mogi
Tags: cyclic gmp, glaucoma, intraocular pressure, macaca fascicularis, oryctolagus cuniculus
Investigative Ophthalmology & Visual Science April 2018, Vol.59, 1704-1716. doi:https://doi.org/10.1167/iovs.18-23772
Endothelial Protein C–Targeting Liposomes Show Enhanced Uptake and Improved Therapeutic Efficacy in Human Retinal Endothelial Cells Open Access
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Anthoula Arta; Anne Z. Eriksen; Fredrik Melander; Paul Kempen; Michael Larsen; Thomas L. Andresen; Andrew J. Urquhart
Tags: endothelial protein c receptor, liposomes, endothelial cells
Investigative Ophthalmology & Visual Science April 2018, Vol.59, 2119-2132. doi:https://doi.org/10.1167/iovs.18-23800

Retina

Humoral Immune Response After Intravitreal But Not After Subretinal AAV8 in Primates and Patients Open Access
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Felix F. Reichel; Tobias Peters; Barbara Wilhelm; Martin Biel; Marius Ueffing; Bernd Wissinger; Karl U. Bartz-Schmidt; Reinhild Klein; Stylianos Michalakis; M. Dominik Fischer; for the RD-CURE Consortium
Investigative Ophthalmology & Visual Science April 2018, Vol.59, 1910-1915. doi:https://doi.org/10.1167/iovs.17-22494
Distinctive Analysis of Macular Superficial Capillaries and Large Vessels Using Optical Coherence Tomographic Angiography in Healthy and Diabetic Eyes Open Access
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Jianqin Lei; Enhui Yi; Yan Suo; Cheng Chen; Xiayu Xu; Wenxiang Ding; Nizar Saleh Abdelfattah; Xiaojuan Fan; Huiqin Lu
Tags: angiogram, blood capillaries, diabetes mellitus, eye, large blood vessels
Investigative Ophthalmology & Visual Science April 2018, Vol.59, 1937-1943. doi:https://doi.org/10.1167/iovs.17-23676
Volume-Rendered Projection-Resolved OCT Angiography: 3D Lesion Complexity Is Associated With Therapy Response in Wet Age-Related Macular Degeneration Open Access
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Peter L. Nesper; Brian T. Soetikno; Alison D. Treister; Amani A. Fawzi
Tags: angiogram, anti-vascular endothelial growth factor therapy, choroidal neovascularization, exudative age-related macular degeneration, fluid flow
Investigative Ophthalmology & Visual Science April 2018, Vol.59, 1944-1952. doi:https://doi.org/10.1167/iovs.17-23361
Optical Coherence Tomography Minimum Intensity as an Objective Measure for the Detection of Hydroxychloroquine Toxicity Open Access
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Ali M. Allahdina; Paul F. Stetson; Susan Vitale; Wai T. Wong; Emily Y. Chew; Fredrick L. Ferris III; Paul A. Sieving; Catherine Cukras
Investigative Ophthalmology & Visual Science April 2018, Vol.59, 1953-1963. doi:https://doi.org/10.1167/iovs.17-22668
The Absence of Indoleamine 2,3-Dioxygenase Inhibits Retinal Capillary Degeneration in Diabetic Mice Open Access
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Rooban B. Nahomi; Sruthi Sampathkumar; Angela M. Myers; Lynda Elghazi; Dawn G. Smith; Jie Tang; C. Allen Lee; Timothy S. Kern; Ram H. Nagaraj; Patrice E. Fort
Tags: blood capillaries, diabetes mellitus, mice, tissue degeneration, tryptophan oxygenase
Investigative Ophthalmology & Visual Science April 2018, Vol.59, 2042-2053. doi:https://doi.org/10.1167/iovs.17-22702
Targeted Drug Delivery in the Suprachoroidal Space by Swollen Hydrogel Pushing Open Access
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Jae Hwan Jung; Patcharin Desit; Mark R. Prausnitz
Tags: eye, hydrogel, injections, oryctolagus cuniculus
Investigative Ophthalmology & Visual Science April 2018, Vol.59, 2069-2079. doi:https://doi.org/10.1167/iovs.17-23758
Characteristics of Retinal Structural and Microvascular Alterations in Early Type 2 Diabetic Patients Open Access
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Qi Chen; Fan Tan; Yufei Wu; Xiran Zhuang; Chaoming Wu; Yuheng Zhou; Yingzi Li; Dan Cheng; Jianhua Wang; Fan Lu; Meixiao Shen
Tags: diabetes mellitus, microvascular network, nonproliferative diabetic retinopathy, fractals
Investigative Ophthalmology & Visual Science April 2018, Vol.59, 2110-2118. doi:https://doi.org/10.1167/iovs.17-23193
Importance of Considering the Middle Capillary Plexus on OCT Angiography in Diabetic Retinopathy Open Access
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Alex C. Onishi; Peter L. Nesper; Philipp K. Roberts; Ganna A. Moharram; Haitao Chai; Lei Liu; Lee M. Jampol; Amani A. Fawzi
Tags: angiogram, blood capillaries, diabetic retinopathy, eye, nonproliferative diabetic retinopathy
Investigative Ophthalmology & Visual Science April 2018, Vol.59, 2167-2176. doi:https://doi.org/10.1167/iovs.17-23304

Retinal Cell Biology

Photoreceptor Cell–Derived CAPN5 Regulates Retinal Pigment Epithelium Cell Proliferation Through Direct Regulation of SLIT2 Cleavage Open Access
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Yan Wang; Heming Li; Shihu Zang; Fanfan Li; Yingying Chen; Xiao Zhang; Zongming Song; Qing Peng; Feng Gu
Tags: cell proliferation, cytokinesis, mice, photoreceptors, retinal pigment epithelium
Investigative Ophthalmology & Visual Science April 2018, Vol.59, 1810-1821. doi:https://doi.org/10.1167/iovs.17-22689
Topical Ripasudil Suppresses Retinal Ganglion Cell Death in a Mouse Model of Normal Tension Glaucoma Open Access
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Kei Akaiwa; Kazuhiko Namekata; Yuriko Azuchi; Hiroki Sano; Xiaoli Guo; Atsuko Kimura; Chikako Harada; Yoshinori Mitamura; Takayuki Harada
Tags: mice, neuroprotection, low tension glaucoma, retinal ganglion cells
Investigative Ophthalmology & Visual Science April 2018, Vol.59, 2080-2089. doi:https://doi.org/10.1167/iovs.17-23276

Visual Psychophysics and Physiological Optics

Consistency of Structure-Function Correlation Between Spatially Scaled Visual Field Stimuli and In Vivo OCT Ganglion Cell Counts Open Access
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Nayuta Yoshioka; Barbara Zangerl; Jack Phu; Agnes Y. J. Choi; Sieu K. Khuu; Katherine Masselos; Michael P. Hennessy; Michael Kalloniatis
Tags: cell count, cohort studies, ganglia, glaucoma, visual fields
Investigative Ophthalmology & Visual Science April 2018, Vol.59, 1693-1703. doi:https://doi.org/10.1167/iovs.17-23683
Color Vision in Aniridia Open Access
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Hilde R. Pedersen; Lene A. Hagen; Erlend C. S. Landsend; Stuart J. Gilson; Øygunn A. Utheim; Tor P. Utheim; Maureen Neitz; Rigmor C. Baraas
Tags: aniridia, color vision, color, foveal hypoplasia
Investigative Ophthalmology & Visual Science April 2018, Vol.59, 2142-2152. doi:https://doi.org/10.1167/iovs.17-23047
Peripheral Defocus of the Monkey Crystalline Lens With Accommodation in a Lens Stretcher Open Access
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Bianca Maceo Heilman; Fabrice Manns; Marco Ruggeri; Arthur Ho; Alex Gonzalez; Cor Rowaan; Andres Bernal; Esdras Arrieta; Jean-Marie Parel
Tags: cercopithecidae, gurneys, lens (device), lens, crystalline, visual accommodation
Investigative Ophthalmology & Visual Science April 2018, Vol.59, 2177-2186. doi:https://doi.org/10.1167/iovs.17-23273

Clinical Trials

Fundus Autofluorescence Lifetime Patterns in Retinitis Pigmentosa Open Access
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Chantal Dysli; Kaspar Schuerch; Pascal Escher; Sebastian Wolf; Martin S. Zinkernagel
Tags: diagnostic imaging, fluorescence, fundus autofluorescence imaging, retinitis pigmentosa
Investigative Ophthalmology & Visual Science April 2018, Vol.59, 1769-1778. doi:https://doi.org/10.1167/iovs.17-23336

Perspective

Essential Infantile Esotropia: Potential Pathogenetic Role of Extended Subcortical Neuroplasticity Open Access
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Michael C. Brodsky
Tags: infantile esotropia, neuronal plasticity, subcortical, eye
Investigative Ophthalmology & Visual Science April 2018, Vol.59, 1964-1968. doi:https://doi.org/10.1167/iovs.18-23780

Letters to the Editor

The First Histologic Evidence of a Paravascular Pathway Within the Optic Nerve Open Access
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Peter Wostyn; Veva De Groot; Debby Van Dam; Kurt Audenaert; Peter Paul De Deyn; Hanspeter Esriel Killer
Tags: optic nerve
Investigative Ophthalmology & Visual Science April 2018, Vol.59, 1717. doi:https://doi.org/10.1167/iovs.17-23119
Author Response: The First Histologic Evidence of a Paravascular Pathway Within the Optic Nerve Open Access
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Yeni H. Yucel; Emily Mathieu; Neeru Gupta
Tags: optic nerve
Investigative Ophthalmology & Visual Science April 2018, Vol.59, 1718. doi:https://doi.org/10.1167/iovs.18-24164
The “Ocular Glymphatic System”: An Important Missing Piece in the Puzzle of Optic Disc Edema in Astronauts? Open Access
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Peter Wostyn; Peter Paul De Deyn
Tags: astronauts, papilledema
Investigative Ophthalmology & Visual Science April 2018, Vol.59, 2090-2091. doi:https://doi.org/10.1167/iovs.17-23263
Author Response: The “Ocular Glymphatic System”: An Important Missing Piece in the Puzzle of Optic Disc Edema in Astronauts? Open Access
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Yeni Yucel; Emily Mathieu; Neeru Gupta
Tags: astronauts, papilledema
Investigative Ophthalmology & Visual Science April 2018, Vol.59, 2092-2093. doi:https://doi.org/10.1167/iovs.17-23407

Erratum

Erratum Open Access
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Investigative Ophthalmology & Visual Science April 2018, Vol.59, 1800. doi:https://doi.org/10.1167/iovs.17-21506a
Erratum Open Access
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Investigative Ophthalmology & Visual Science April 2018, Vol.59, 1801. doi:https://doi.org/10.1167/iovs.17-22508a
Erratum Open Access
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Investigative Ophthalmology & Visual Science April 2018, Vol.59, 1936. doi:https://doi.org/10.1167/iovs.17-21645a
Erratum Open Access
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Investigative Ophthalmology & Visual Science April 2018, Vol.59, 1985. doi:https://doi.org/10.1167/iovs.17-23044a
Erratum Open Access
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Investigative Ophthalmology & Visual Science April 2018, Vol.59, 2153. doi:https://doi.org/10.1167/iovs.17-21530a
Copyright © 2025 Association for Research in Vision and Ophthalmology.
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