Volume 59 Issue 9 | IOVS

An Emergent Paradigm for Vision Research: Proteostasis, Variation and Precision Management of Human Disease Open Access

William E. Balch

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 1. doi:

Immunoproteasome regulates multiple signaling pathway in ther Retinal Pigment Epithelium Open Access

Deborah A. Ferrington

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 2. doi:

The role of protein biogenesis, trafficking and ER homeostasis in retinitis pigmentosa Open Access

Michael E. Cheetham

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 3. doi:

Photoreceptor autophagy: role in maintaining homeostasis Open Access

David N. Zacks

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 4. doi:

Molecular details of protein misfolding in myocilin-associated glaucoma Open Access

Raquel L. Lieberman

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 5. doi:

Molecular Architecture of the Mammalian Circadian Clock Open Access

Joseph S Takahashi

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 6. doi:

Retinal and brain circuits underlying the effects of light on behavior Open Access

Samer Hattar

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 7. doi:

The Retina, Dopamine, and Circadian Rhythms Open Access

P. Michael Iuvone

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 8. doi:

How does melanopsin help us see? Open Access

Robert J. Lucas

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 9. doi:

ipRGCs in retinal disease Open Access

Beatrix K. Feigl

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 10. doi:

Circadian rhythms in eye growth Open Access

Debora L. Nickla

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 11. doi:

Comparative connectomics of the mammalian retina Open Access

Kevin L. Briggman

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 12. doi:

The functional organisation of bipolar cell pathways Open Access

Thomas Euler

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 13. doi:

Discovering visual pathway origins in the center of the human foveola with connectomics Open Access

Dennis M. Dacey

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 14. doi:

Circuit remodeling in retinal degeneration Open Access

Bryan W. Jones

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 15. doi:

Retinal glia - physiology and disease Open Access

Thomas W. Gardner

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 16. doi:

Cell surgery in retinitis pigmentosa: restoration and visual prognosis Open Access

Paolo G. Limoli; Enzo Maria Vingolo; Marcella Nebbioso; Sergio Zaccaria Scalinci; Marco U Morales; Celeste S. S. Limoli

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 17. doi:

Molecular Genetic Screening In A Series Of 852 Patients With Inherited Retinal Dystrophies From One German Reference Center Open Access

Ulrich Kellner; Heidi Stoehr; Simone Kellner; Silke Weinitz; Ghazaleh Farmand; Birgit Lindau; Bernhard HF Weber

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 18. doi:

Phenotypic expression of EYS mutations in patients with autosomal recessive retinitis pigmentosa in northern Sweden
Open Access

Marie Burstedt; Frida Jonsson; Ida Maria Westin; Irina Golovleva

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 19. doi:

Long-term clinical course of Japanese patients with retinitis pigmentosa caused by mutations in pre-mRNA splicing gene Open Access

Kentaro Kurata; Katsuhiro Hosono; Yoshihiro Hotta

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 20. doi:

Association between Macular Blood Flow and Choroidal Structure and their Relationships to Visual Function in Retinitis Pigmentosa Open Access

Yusuke Murakami; Jun Funatsu; Shunji Nakatake; Kohta Fujiwara; Takashi Tachibana; Toshio Hisatomi; Shigeo Yoshida; Shozo Sonoda; Taiji Sakamoto; Koh-hei Sonoda; Yasuhiro Ikeda

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 21. doi:

The Associations between Visual Acuity and Retinal Thickness in Retinitis Pigmentosa Using The Optical Coherence Tomography Open Access

Amal Qassim Aldarwesh; hanan mofty; Samah Mahmoud Fawzy; Reem Saleh Al-Qahtani

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 22. doi:

CEP290 mutation spectrum in Germany and delineation of the associated phenotype Open Access

Ditta Zobor; Britta Feldhaus; Nicole Weisschuh; Fadi Nasser; Eberhart Zrenner; Susanne Kohl

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 23. doi:

Step-wise genetic diagnosis for retinitis pigmentosa and Usher syndrome by Next-Generation Sequence Open Access

Shogo Numa; Akio Oishi; Maho Oishi; Tomoko Hasegawa; Kenji Ishihara; manabu miyata; Akitaka Tsujikawa

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 24. doi:

Relationship of visual field sensitivity in central 10-degrees to thickness of different retinal layers in eyes of patients with retinitis pigmentosa Open Access

Akira Sayo; Shinji Ueno; Taro Kominami; Daiki Inooka; Hiroko Terasaki

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 25. doi:

CRISPR-Cas9 RNP complex, delivered via lipid nanoparticle, is effective in disruption of RHO gene in vitro Open Access

Amirmohsen Arbabi; Christine Spee; David R Hinton; Peter Z. Qin; Cheryl Mae Craft; Sarah F Hamm-Alvarez; Hossein Ameri

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 26. doi:

Quantification of macular microvascular changes in patients with retinitis pigmentosa using optical coherence tomography angiography Open Access

Daiki Inooka; Shinji Ueno; Taro Kominami; Akira Sayo; Satoshi Okado; Yasuki Ito; Hiroko Terasaki

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 27. doi:

Relationships among Spectral Domain Optical Coherence Tomography (SD-OCT) Parameters and Semi-automated Kinetic Perimetry (SKP) Parameters in Subjects with Autosomal Dominant Retinitis Pi... Open Access

Kirsten G Locke; Donald C Hood; David G Birch

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 28. doi:

Use of optical coherence tomography angiography to estimate central visual function Open Access

Kosuke Nakajima; Shotaro Asano; Tatsuya Inoue; Ryo Obata; Ryo Asaoka; Makoto Aihara

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 29. doi:

Test-retest Reliability of MP1 and MAIA Microperimetry in Retinitis Pigmentosa Open Access

Mustafa Iftikhar; Jiangxia Wang; Peter A Campochiaro

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 30. doi:

Lack of Association Between Fundus Autofluorescence Loss and Retinal Vascular Diameter in Retinitis Pigmentosa Open Access

Hossein Ameri; Amirmohsen Arbabi; Preny Karamian; Mahnaz Shahidi

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 31. doi:

Investigating plasticity in Retinitis Pigmentosa using retinotopic representation of the lesion projection zone Open Access

Jeiran Choupan; Eric Jung; Vivek R Patel; Chris Purington; Noelle Stiles; Jessica Ijams Wolfing Morgan; Andrew S Bock; Kimberly K Gokoffski; Junyan Wang; Meng Law; Andrew Moshfeghi; Amir H Kashani; Hossein Ameri; Geoffrey K. Aguirre; James D. Weiland; Yonggang Shi

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 32. doi:

Assessment of Central Visual Function in Patients with Retinitis Pigmentosa Open Access

Kohta Fujiwara; Yasuhiro Ikeda; Yusuke Murakami; Takashi Tachibana; Jun Funatsu; Yoshito Koyanagi; Shunji Nakatake; Noriko Yoshida; Shintaro Nakao; Toshio Hisatomi; Shigeo Yoshida; Takeshi Yoshitomi; Tatsuro Ishibashi; Koh-hei Sonoda

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 33. doi:

Targeted Next Generation Sequencing Reveals a Novel Frameshift MERTK Mutation in Retinitis Pigmentosa Open Access

Mu Yang; Shujin Li; Xianjun Zhu; Zhenglin Yang

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 36. doi:

Associations Between Outer Retinal Structures and Focal Macular Electroretinograms in Patients with Retinitis Pigmentosa
Open Access

Taro Kominami; Shinji Ueno; Hiroko Terasaki

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 37. doi:

Prevalence of mutations in PDE6B gene in autosomal recessive retinitis pigmentosa in the aim of gene therapy Open Access

Jean-Yves Deslandes; Mathilde Giraud; Bertrand Isidor; Patricia Talarmain; Ingrid Maury; Severine Marconi; Guylene Le Meur; Michel Weber; Isabelle Meunier; Christian Hamel; Stéphane Bezieau

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 38. doi:

Phenotypic variability in patients with RP1 mutations Open Access

Rachel M Huckfeldt; Carly Murphy; Brian Palmer Hafler; Demetrios G. Vavvas; Lucy H Young; Eric A Pierce; Emily Place

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 39. doi:

Improvements in test-retest variability of static perimetry by censoring results with low sensitivity in retinitis pigmentosa Open Access

Anushka Mistry; Leon Nehmad; Rakin Khan; Gislin Dagnelie; John S Pollack; Ava K Bittner

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 40. doi:

RPGR gene editing with CRISPR-Cas 9 system in Retinal degeneration 9 (Rd9) mice to correct a disease mutation and phenotype Open Access

Amal Alsufyani; Wenhan Yu; Jessica Gumerson; Lijin Dong; Zhijian Wu; Tiansen Li

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 41. doi:

Novel RP1 Mutations in Autosomal Recessive Retinitis Pigmentosa by targeted next generation sequencing Open Access

Shujin Li; Mu Yang; Zhenglin Yang; Xianjun Zhu

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 42. doi:

Extensive phenotyping in CRB1-associated retinal dystrophies: defining clinical endpoints for gene therapy trials Open Access

Mays Talib; Mary van Schooneveld; Jan Wijnholds; Maria M van Genderen; N. Schalij-Delofs; Ralph Florijn; Frans P Cremers; Ingeborgh Born; Alberta A H J Thiadens; Carel C B Hoyng; Caroline C W Klaver; Arthur A Bergen; Camiel Boon

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 43. doi:

Pigmentary autosomal dominant familiar retinopathy of penetrance and variable expressivity: Report of a deletion not reported in the human rhodopsin gene in a series of family cases Open Access

Maria Moussalli

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 44. doi:

Progression of Retinitis Pigmentosa on Multimodal Imaging: The PREP-1 Study Open Access

Syed Mahmood Ali Shah; Mustafa Iftikhar; Bushra Usmani; Abanti Sanyal; Ramandeep Kaur; Marili Lemus; April Nefalar; Saleema A. Kherani; Simrat Sodhi; Saghar Bagheri; Etienne M Schonbach; Nadia Junaid; Peter A Campochiaro; Hendrik P Scholl

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 45. doi:

Early Structural and Functional Abnormalities in Leber Congenital Amaurosis Caused by Mutations in RDH12 Open Access

Tomas S Aleman; Katherine E Uyhazi; Leona Serrano; Scott J Bowman; Denise J Pearson; Albert M Maguire; Jean Bennett

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 46. doi:

A novel mutation in KIF3B in a family with dominant retinitis pigmentosa and polydactyly Open Access

Stephen P Daiger; Lori S Sullivan; Sara J Bowne; Elizabeth L Cadena; Kinga Maria Bujakowska; Eric A Pierce; Michael B Gorin; Xénia Latypova; Erica E Davis; Nicholas Katsanis; Ludovic Martin; Laurence Legeai-Mallet; Benjamin Cogne; Stéphane Bezieau; Thomas Besnard; Bertrand Isidor

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 47. doi:

A Natural History Study of Visual Function in Patients with Usher Syndrome Type 1C. Open Access

Meredith Harrell Hartman; Katelyn N. Robillard; Vincent Sun; Irma Lopez; Mariam Ibrahim; Kelsey Walsdorf; Maria Reinoso; Robert K Koenekoop; Jennifer J Lentz

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 48. doi:

Morpho-functional links in Usher Syndrome: ultra-widefield fundus autofluorescence and optical coherence tomography findings and their correlation with visual acuity and electrophysiology... Open Access

Nina Mustafic; Federica Ristoldo; Alessandro Invernizzi; Robyn V Jamieson; John R Grigg

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 49. doi:

Longitudinal Reductions in Thickness of Foveal Inner Retinal Layers in Relation to Progressive Vision Loss in Retinitis Pigmentosa Patients Open Access

Robert Zusman; Aaron Carass; Yufan He; Jerry Prince; Howard S Ying; Gislin Dagnelie; Alfred Vinnett; Ava K Bittner

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 50. doi:

Quantitative comparison of near-infrared versus short-wave autofluorescence imaging in monitoring progression of retinitis pigmentosa Open Access

Ruben Jauregui; xuan cui; Jimmy Duong; Stephen H Tsang

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 51. doi:

One-year outcomes of dexamethasone implant versus oral acetazolamide for the treatment of cystoid macular edema in patients with retinitis pigmentosa Open Access

Daniele Veritti; Valentina Sarao; Katia De Nadai; Francesco Parmeggiani; Paolo Lanzetta

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 52. doi:

Investigating the usefulness of fundus autofluorescence in retinitis pigmentosa Open Access

Saori Tsuneyoshi; Keiko Azuma; Tatsuya Inoue; Ryo Asaoka; Makoto Aihara; Ryo Obata

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 53. doi:

Full-Field Stimulus Thresholds (FSTs) in Subjects with Inherited Retinal Degenerations (IRDs) – a 10 Years Review Open Access

Martin Klein; Paulina Mejia; Daniel Galles; David G Birch

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 54. doi:

Phase I/II study to evaluate the safety and biological activity of HORA-PDE6B in patients with PDE6B retinitis pigmentosa (MIM#613801) Open Access

Le Meur Guylene; pierre Lebranchu; jean baptiste Deltour; Fanny Billaud; Nicolas Delaunay; Frédéric Lallemand; Severine Marconi; Michel Weber

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 55. doi:

PDGFRβ blockade inhibits choroidal neovascularization and fibrosis in a laser-induced CNV model in mice Open Access

Ye Liu; Kousuke Noda; Di Wu; Miyuki Murata; Atsuhiro Kanda; Susumu Ishida

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 56. doi:

Firsts steps in the development of a topical CeO₂NPs treatment to fight dry AMD progression using the DKOrd8 mouse model Open Access

Anna Badia; Anna Salas Torras; Ignacio Salvo Ibanez; Barbara Ferreira de Souza; Eudald Casals; Victor Puntes; Miguel Angel Zapata; Laura Fontrodona; Jose Garcia-Arumi

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 58. doi:

Effect of intravitreal triamcinolone acetonide injections on persistent sub-retinal fluid in wet-AMD patients receiving conventional anti-VEGF therapy Open Access

Danielle Wentzell; Chris Jackman

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 59. doi:

Discovery and Planned Optimization of a Complement Factor C3-Inactivating Alterase, CB-2782 Open Access

Eric Furfine; Martin Stanton; Brajesh Kumar; Nassim Usman; David Sloane; Mikhail Popkov; Edwin Madison

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 60. doi:

Novel Retina Specific Laminin Isoforms Recapitulate Retinal Interphotoreceptor Matrix to Generate Human Embryonic Stem Cell-derived Photoreceptors Open Access

Hwee Goon Tay; Zuhua Cai; Yang Sun; Jing Guo; Aida Moreno-Moral; Wei Sheng Tan; Karl Tryggvason

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 61. doi:

Dynamics of inflammatory factors in aqueous humor under Ranibizumab or Aflibercept treatment for age-related macular degeneration Open Access

Ryosuke Motohashi; Hidetaka Noma; Kanako Yasuda; Osamu Kotake; Hiroshi Goto; Masahiko Shimura

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 62. doi:

PEG-Fab Conjugates with tunable hydrodynamic radii for long-acting delivery Open Access

Guannan He; Maciej Paluch; Guanghui Han; Wendy Sandoval; Philip Hass

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 63. doi:

P2X7R inhibition activates autophagy and impairs the inflammasome response in the RPE Open Access

James T Handa; Hanna Eilken; Charles Eberhart; Marcus Karlstetter; Hartmut Schirok; Meysam Yazdankhah; Peng Shang; Marisol del Valle Cano; Jeff S Mumm; Alexander Zink; Carsten Terjung; Bernd Kalthof; Debasish Sinha

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 64. doi:

The ROCK inhibitor ripasudil suppresses angio-fibrotic switch in subretinal fibrovascular proliferation
Open Access

Iori Wada; Shintaro Nakao; Keijiro Ishikawa; Muneo Yamaguchi; Yoshihiro Kaizu; Shigeo Yoshida; Koh-hei Sonoda

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 65. doi:

Effect of two Laser Treatments on Bruchs Membrane Thickness in a Mouse Model of Age-related Macular Degeneration Open Access

Elisabeth Richert; Jan Tode; Katharina Vinh; Alexa Karina Klettner; Stefan Otto Johannes Koinzer; Ralph Lucius; Ralf Brinkmann; Johann Roider

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 66. doi:

A novel bispecific inhibitor targeting VEGF and complement system suppressed angiogenesis in model of neovascular age-related macular degeneration Open Access

Shiqi Yang; Tong Li; Xueting Luo; Xiaodong Sun

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 67. doi:

A Surgical Technique for Subretinal Delivery of Human iPSC-RPE Patch Open Access

Juan Amaral; Steve T Charles; Vladimir Kristov; Arvydas Maminishkis; Kapil Bharti

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 68. doi:

Systemic PDE 5/6 treatment of macular disease and dystrophy – long term vision and OCT results Open Access

D Jackson Coleman; Winston Lee; Stanley Chang; Suzanne Daly; Harriet O Lloyd; Stephen H Tsang

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 69. doi:

Systematic treatment with trimethoprim/sulfamethoxazole (Ditrim) significantly inhibits spontaneous choroidal neovascularization (sCNV) in the JR5558 mouse model Open Access

YU SU; Franco Rossato; Ashley Mackey; Yin Shan Eric Ng

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 70. doi:

Gelatin-based Hydrogel as a Vehicle for Retinal Progenitor Cell Transplantation in Rat Retina Open Access

Jeayoung Park; Petr Baranov; Hany Abdelgawad; Aybike Aydin; Wanting Niu; Myron Spector; Michael J. Young

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 71. doi:

APL-2, a Complement C3 Inhibitor, Slows the Growth of Geographic Atrophy Secondary to AMD: 18-month Results of a Phase 2 Trial (FILLY) Open Access

Charles Clifton Wykoff; Federico Grossi

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 72. doi:

Expression of an Anti-Inflammatory Peptide using a Minicircle-Plasmid delivery system in RPE Cell Culture Open Access

Max Brinkmann; Maximilian Kurz; Markus Mandl; Zouhair Aherrahrou; Armin Mohi; Salvatore Grisanti; Mahdy Ranjbar; Martin Rudolf

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 73. doi:

Use of Microperimetry and Visual Electrophysiology to Improve Success of Implantable Miniature Telescopic Lens in Patients with Central Macular Atrophy Open Access

Paul Namkoong; Yianni Yiannakou; Lynnette Hoai Nguyen; Keshav Narain; Randal Pham

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 74. doi:

Efficacy of Micropulse Laser in Treatment of Idiopathic Polypoidal Choroidal Vasculopathy (IPCV) Unresponsive to Aflibercept Injections Open Access

Ahmed ALNAHRAWY; Abike Goodluck; Saad Younis

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 75. doi:

Phase I/IIa Clinical Trial of Human Embryonic Stem Cell (hESC)-Derived Retinal Pigmented Epithelium (RPE, Opregen^®) Transplantation in Advanced Dry Form Age-Related Macular Degeneration (... Open Access

Eyal Banin; Yitzchak Hemo; Tareq Jaouni; Devora Marks-Ohana; Maria Gurevich; Oscar Cuzzani; David S Boyer; Benjamin Reubinoff

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 77. doi:

Measurement of the Dose of Triamcinolone Acetonide Produced by Office Based Centrifuge Concentration Open Access

Nathan Farley; Rahul Komati; Desiree Albert; Alice Zhang; Kyle Anderson; Michael Ober

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 78. doi:

Incidence of ocular hypertension following intravitreal injection of 2mg triamcinolone Open Access

Philip Storey; Anthony Obeid; Maitri Pancholy; Jake Goodman; Xinxiao Gao; Durga S Borkar; Daniel Su; Carl Regillo

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 79. doi:

In vivo Effects of CCFD9260S Following Intravitreal Administration to Cynomolgus Monkeys Open Access

Helen S Booler; Nardos Tassew; Aija MacKenzie; Hong Liu; Deborah O'Connor; Florence Lorget; Paul E Miller; Tim Streit; T Michael Nork; James N Ver Hoeve; Cinzia Stella; Yanqiu Liu; Daniela Bumbaca; Vladimir Bantseev

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 80. doi:

Initial eight years of experience with the intravitreal dexamethasone implant: A retrospective chart review Open Access

Josh O Wallsh; Charlotte Luths; Esmeralda Gallemore; Ron Gallemore

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 81. doi:

The Effect of the Vitreous on the Localization and Outcomes of Intravitreal Injections of Sustained-Release Dexamethasone Implants Open Access

Nicole Koulisis; Stavros N. Moysidis; Bruce Burkemper; Brian Do; Andrew A Moshfeghi; Hossein Ameri; Amir H Kashani; Narsing A Rao; Mark S. Humayun; Damien C Rodger

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 82. doi:

The permeability of eyelid skin to topically applied lidocaine Open Access

Krisztina Emeriewen; George Saleh; William McAuley; Michael Cook

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 83. doi:

An Alternative Surgical Approach for Marcus Gunn Jaw Wink Ptosis Open Access

Karen E Revere; Akosua Nti; William Katowitz; James A Katowitz; Gil Binenbaum

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 84. doi:

The Anterior Approach for Contact Lens Related Ptosis Correction Open Access

Livia Teo; Stephanie Lang; Se Ji Jung; Gillian Teh

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 85. doi:

Comparison of postoperative course of aponeurotic ptosis surgery in eyes with glaucoma filtration bleb and in eyes after intraocular surgery without bleb Open Access

Risako Yamamoto; Rika Shirakawa; Tetsuya Toyono; Rei Sakata; Reina Akiyama; Yurika Aoyama; Mika Noda; Junko Yoshida; Takashi Miyai; Tomohiko Usui; Makoto Aihara

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 87. doi:

Long Term Outcomes of Frontalis Suspension Surgery Using Autogenous Fascia Lata Slings in Children with Congenital Ptosis Open Access

Michael R Chua; Danielle M Lo; James A Katowitz; William R Katowitz

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 88. doi:

Goldmann Ptosis Visual Field Results in Eyes with Panretinal Photocoagulation Open Access

Giancarlo A Garcia; Thomas A Vo; Philip Ngai; Marc A Yonkers; Jeremiah P Tao

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 89. doi:

Timing of Congenital Ptosis Repair in Relation to the Development of Strabismus Open Access

Laura Kueny; Heather de Beaufort

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 90. doi:

Evaluation of ocular surface condition and subjective happiness in blepharoplastic surgery Open Access

Manami Kuze; Masaki Koizumi; Yayoi Tanaka; Kazuno Negishi; Masahiko Ayaki

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 91. doi:

Ocular Pyogenic Granulomas Treated with Topical Timolol Open Access

Arpine Barsegian; Nora Silverman; Roman Shinder

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 92. doi:

NEW METHOD TO SIMULATE DERMATOCHALASIS SURGERY Open Access

Eduardo Arenas Archila; ALEXANDRA MIETH

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 93. doi:

Quantitative Changes in Corneal Exposure during Vertical Gaze: A Clinical Model for Eyelid Contour Analysis Open Access

Yadan Quan; Tiran Zhang; Minbin Yu; Rong Lu

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 97. doi:

Self-Adhering Magnetic Device to Treat Corneal Exposure Open Access

Safwan Tayeb; Raman Michael; Pete Setabutr; Charles Qian Yu; Mark Rosenblatt

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 98. doi:

Visual acuity trends of patients wearing PROSE for exposure keratopathy after oculoplastic surgery
Open Access

Kalla A Gervasio; Elizabeth Marlow; Michelle N. Lee; Gary J. Lelli

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 99. doi:

Does Cosmetic Related Lacrimal Sac Pigmentation Play a Role in Chronic Dacryocystitis? Open Access

Fatimah Alhammad; DEEPAK P EDWARD; Azza Maktabi; Rajiv Khandekar; Osama Alsheikh

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 100. doi:

External Dacryocystorhinostomy: A Comparison of Ultrasonic Bone Aspiration to High Speed Drilling Open Access

Vikram Shankar; Krishna Kalyam; Steven M Couch

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 101. doi:

Investigation of the mechanism of onset of dacryocystitis after rebamipide ophthalmic solution administration Open Access

Fumika Hotta; Hiroshi Eguchi; Shunji Kusaka; Mariko Hasegawa; chika miyazaki; Miou Hirose; Futoshi Taketani; Tsuguyoshi Sasaki; Yasushi Inoue; Yoshikazu Shimomura

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 102. doi:

Estimation of Eyelid Pressure Using a Blepharo-Tensiometer in Patients With Functional Nasolacrimal Duct Obstruction Open Access

Jinsoo Kim; Sang Mok Lee; Youn Joo Choi; Min Joung Lee

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 103. doi:

Probing and syringing outcomes for Congenital Nasolacrimal Duct Obstruction: A retrospective study. Open Access

Olayinka Ann-marie Williams; Hariharan Narendran; Pedro Gonzalez; Muhammad Amanullah

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 104. doi:

Cost Comparison of Different Treatment Approaches to Dacryocystitis and Dacrocystocele Open Access

Erin Sieck; Anne M Lynch; Jennifer L Patnaik; Jasleen K Singh

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 105. doi:

Idiopathic Dacryoadenitis Treated with Intralesional Rituximab Open Access

Charles Grabel Miller; Arpine Barsegian; Roman Shinder

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 106. doi:

Non-coding RNA Expression in Inflammatory Dacryoadenitis Open Access

Marwan Ali; Arun Balasubramaniam; Mark Maienschein-Cline; Shreya Wadhwa; Dhara Shah; Kyung-No Son; Sushma Kalmodia; Vinay Kumar Aakalu

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 107. doi:

A rabbit model of lacrimal-duct mucosal epithelium disorder with benzalkonium chloride Open Access

Michiko Tsukamoto; Hiroshi Tanaka; Tomonori Nakayama; Takahiro Nakamura; Akihide Watanabe; Chie Sotozono; Shigeru Kinoshita

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 108. doi:

Rebamipide attenuates lacrimal duct epithelial cell damage in a rabbit model Open Access

Hiroshi Tanaka; Tomonori Nakayama; Michiko Tsukamoto; Takahiro Nakamura; Akihide Watanabe; Chie Sotozono; Shigeru Kinoshita

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 109. doi:

Evisceration versus enucleation following ocular trauma, a retrospective analysis at a level one trauma center Open Access

Donovan Stephen Reed; Wesley Brundridge; Aditya Mehta; Brett Davies

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 110. doi:

Incorporation of survey data from ophthalmologists and first responders in the development of a novel, point-of-injury treatment for ocular trauma Open Access

Michael A Washington; Katherine Duncan; Susannah Waxman; Nils A Loewen; Jenny Y Yu; Morgan V Fedorchak

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 111. doi:

Evisceration and Sympathetic Ophthalmia: Histopathology and PCR analysis of the scleral bed Open Access

Laith Kadasi; Nora V Laver; Kara Lombardo; Nelli Lakis; Michael Migliori

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 112. doi:

Stratifying risk in operating room fires: local oxygen concentrations in open faced draping with nasal cannula and basic respiration mask Open Access

Aleksey Mishulin; Brandon Kennedy; Coleen Palileo; Kathryn P. Winkler; Geoffrey Gladstone

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 113. doi:

Successes in Education Through the Use of Social Media Open Access

Jason Jensen; Kendra DeAngelis; Brian Fowler

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 114. doi:

Reducing Adenoviral Patient Infected Days (RAPID): Prevalence of Polymerase Chain Reaction (PCR) Confirmed Adenovirus Among Patients Presenting With Acute Conjunctivitis Open Access

Mary Migneco; Mathew Margolis; Christina Morettin; Tammy Than; Meredith Whiteside; Ellen Shorter; Jennifer S Harthan; Spencer Johnson; Andy Hartwick; Kelly Olsen; Tave van Zyl; Julia Huecker; Crystal Rosemann; Mae O. Gordon

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 115. doi:

The effects of rebamipide-based gene-expression analysis in human conjunctival epithelial cells Open Access

Keiko Yamada; Mayumi Ueta; Hiromi Nishigaki; Norihiko Yokoi; Chie Sotozono; Shigeru Kinoshita

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 116. doi:

Histopathologic Characterization of Pterygia in the Bronx – 15 Year Evaluation Open Access

Rebecca Weiss; LEDIANA GODUNI; Yssra Soliman; Alexandra Herzlich; Afshin Parsikia; Maria Abadi; Joyce Mbekeani

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 117. doi:

Plastic compressed collagen for ocular surface reconstruction: Evaluation of the biocompatibility in vivo Open Access

Joana Witt; Maria Borrelli; Sonja Mertsch; Gerd Geerling; Kristina Spaniol; Stefan Schrader

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 118. doi:

Evaluation of adenovirus amplified detection kit using tears including conjunctival exudate Open Access

YUSUKE SAEKI; Tomohiro Ueno; Hironori Migita; Tomoko Kawamura; Eiichi Uchio

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 119. doi:

The interaction between dry eye disease and allergic conjunctivitis in mice Open Access

Tatsuma Kishimoto; Ken Fukuda; Waka Ishida; Atsuki Fukushima

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 120. doi:

Upregulation of RelB in the Post-Operative Conjunctiva and its Role in Regulating Inflammation Open Access

Li-Fong Seet; Li Zhen Toh; Stephanie Chu; Tina Wong

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 121. doi:

Long-term prognosis of vernal keratoconjunctivitis. Open Access

Ayaka Mishima; YUSUKE SAEKI; Eiichi Uchio

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 122. doi:

Rapamycin attenuates Th2-driven experimental allergic conjunctivitis Open Access

You sook Hwang; So-Hyang Chung; Yong-Soo Byun; Soojung Shin

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 123. doi:

Effect of UVB exposure on expression of MMP9 in human pterygium fibroblasts Open Access

Naoko Shibata; Shinsuke Shibata; Hidetoshi Ishida; Etsuko Kiyokawa; Hiroshi Sasaki; Eri Kubo

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 125. doi:

The Association Between Pterygium and Elevated Serum Alkaline Phosphatase Level in the South Korean Population: A National Wide Cross-Sectional Study Open Access

Soo Han Kim; Hee Kim

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 126. doi:

Collagen matrix implant in primary pterygium excision
Open Access

Vishal Jhanji; Ka Wai Kam; Alvin Young

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 127. doi:

Decision Making Model for the Operation Method and Prognosis in Pterygium Open Access

Min-Gyu Choi; Jae Chan Kim

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 129. doi:

Impact of pterygium in the ocular surface parameters and tear cytokine profile Open Access

Bruna Duarte; Ana Claudia Viana Wanzeler; Daniel Borges; Alex Treiger Grupenmacher; Monica Alves

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 130. doi:

Electrospun silk fibroin/poly(L-lactic acid-co-ε-caprolactone) scaffolds for conjunctival tissue engineering Open Access

Yao Fu; Qinke Yao; Yang Hu; Fei Yu; Weijie Zhang

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 132. doi:

Wnt/β-catenin signaling pathway promotes self-renewal and stemness of conjunctival stem cell Open Access

Chang Rae Rho; Esther Jang; Kyong Jin Cho; Jungmook Lyu

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 133. doi:

Therapeutic Effect of Intense Pulsed Light on Ocular Demodicosis Open Access

Xiaozhao Zhang; Lan Gong

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 134. doi:

Pathological changes of eyelid in blepharitis induced by Demodex infection
Open Access

Wei Li; Yihui Mao; liying zhang; Hui He; Zuguo Liu

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 135. doi:

Detection and Assessment of Treatment Efficacy of Demodex Blepharitis by In Vivo Confocal Microscopy Open Access

Nicholas Pondelis; Milton M Hom; Leslie E O'Dell; Arsia Jamali; Pedram Hamrah

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 136. doi:

Reproducibility of Liquid Jet Aesthesiometer to Measure Corneal Sensitivity Open Access

Klaus Ehrmann; Cathleen Fedtke; Danny Kho; Nisha Yeotikar; Jennifer Shaw; Monica Jong; Jennie Diec; Daniel Tilia

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 137. doi:

Corneal Pain Has a Negative Impact on the Quality of Life of Patients with Neuropathic Corneal Pain Open Access

Maria J Lopez; Arsia Jamali; Gabriela Dieckmann; Dilruba Koseoglu; Navneet Ramesh; Bijan Khaksari; Pedram Hamrah

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 138. doi:

Using in vivo confocal microscopy to detect the effects of oral mucosal graft on lid margin pathologies in cicatricial ocular surface diseases Open Access

Chin-Te Huang; Yi-Hsuan Wei; Hsiao-Sang Chu; Wei-Li Chen

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 139. doi:

Plasma Pharmacokinetics and Safety following Topical Administration of Brimonidine Tartrate Ophthalmic Solution 0.025% in Healthy Adults Open Access

Lester O Hosten; Jason L Vittitow

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 140. doi:

Regulation of Ikzf1 inducible genes by TLR3 and IPS-1 Open Access

Mayumi Ueta; Hiromi Nishigaki; Kiyoko Oosako; Shigeru Kinoshita

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 141. doi:

Molecular characterization of pterygium fibroblasts in an enhanced serial explant culture technique Open Access

Denise Loya; Alba Guerrero-Martinez; Eduardo Camacho-Martinez; Jorge Luis Domene Hickman; Paloma Lopez; Julio C Hernandez-Camarena; Judith Zavala; Jorge E Valdez

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 142. doi:

Next Generation Exomic Sequencing for Pterygium Open Access

Bo-I Kuo; I-Jong Wang

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 143. doi:

Associations between meibum quality, age and treatment response in patients with meibomian gland dysfunction
Open Access

Vannarut Satitpitakul; Kitiya Ratanawongphaibul

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 145. doi:

Biophysical interactions of gamma-linolenic acid with tear lipids at an air-tear interface Open Access

Poonam Mudgil

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 146. doi:

Closed eye tear neutrophils produce IL-17a in homeostatic conditions Open Access

Cameron K Postnikoff; Katherine S Held; Veena Viswanath; Kelly K Nichols

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 147. doi:

Ocular Surface Temperature in Sjögren's Syndrome Open Access

Maria L. Merino; Javier Belmonte; M Carmen Acosta; Carlos Belmonte; Juana Gallar

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 148. doi:

The effect of menstrual cycle, lifestyle factors and dry eye signs and symptoms on in-vivo corneal confocal microscopy measures
Open Access

Katie Edwards; Luisa Colorado; Lynne Dinh; Sarah Ha; Danica Liu; Annie Luu; Shona Trang; Tina H Yu-Ting; Katrina L Schmid

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 149. doi:

Medial Canthus Hyperpigmentation in Ocular Allergy. Open Access

Rodrigo Crispim C Dompieri; Leonardo César Gontijo; Natasha Cruz; Leonardo Coellho Gontijo; Aquiles Diniz Gontijo; Richard Y Hida; Newton Kara Junior

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 150. doi:

Acrolein exposure to eye causes corneal inflammation, fibrosis, and angiogenesis Open Access

Suneel Gupta; Michael K Fink; Ratnakar Tripathi; Prashant R Sinha; Shyam S Chaurasia; Elizabeth A Giuliano; Nathan Hesemann; Lindsey McDaniel; Emilee M Dailey; Rajiv R Mohan

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 151. doi:

Obstructive Sleep Apnea (OSA), Matrix Metalloproteinase 9 (MMP-9), and Systemic Alterations in Tissue Elastin Open Access

Madeline Ripa; Kumaran Mudaliar; Jay Perlman; Charles S Bouchard

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 152. doi:

Changes in hyper-dry amniotic membrane after implantation in the rabbit conjunctiva Open Access

Akio Miyakoshi; Atsushi Hayashi; Yasuhiko Nishida; Atsushi Tanaka

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 153. doi:

Characterization of corneal sensory nerve activity in young and adult guinea pigs Open Access

Juana Gallar; Kamila Mizerska; Carolina Luna García; Susana Quirce; M Carmen Acosta

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 154. doi:

Coding of small temperature changes by high-background cold thermosensitive trigeminal neurons innervating the ocular surface Open Access

Ariadna Diaz-Tahoces; Enrique Velasco; Carolina Luna García; Fernando A. Carrera; Carlos Belmonte; Juana Gallar; M Carmen Acosta

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 155. doi:

Prospective study on the ocular manifestations in Epidermolysis Bullosa and Autoimmune Blistering Diseases. Open Access

Brendon William Hungchow Lee; Jeremy Tan; Melissa Radjenovic; Lien Tat; Dedee F Murrell; Minas T Coroneo

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 156. doi:

Discomfort self-perception, corneal sensitivity, blinking and tearing in young contact lens wearers. Open Access

M Carmen Acosta; José Ángel Pastor-Zaplana; Marina Morales-Villellas; Mónica Monteserín-Rodríguez; Juana Gallar

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 157. doi:

New human organotypic corneal tissue model for ophthalmic drug delivery, dry eye, and wound healing studies Open Access

Yulia Kaluzhny; Miriam Kinuthia; Thoa Truong; Allison Lapointe; Patrick Hayden; Mitchell Klausner

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 158. doi:

The presentation of patients with psoriasis to opthalmology accident and emergency Open Access

Ellen Kay; Robert John Barry; Gibran Butt

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 160. doi:

Improving Post-procedural Ocular Surface Discomfort in Patients Receiving Regular Intraocular Injections. Open Access

Elisabeth Sledz; John D Pitcher; Kamalesh Ramaiya; Mark Chiu; Frank Wyant; Phillip Jamez Sanchez; C Nathaniel Roybal

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 161. doi:

Ocular Histopathology of Acute and Chronic Pediatric Toxic Epidermal Necrolysis Open Access

Karel D Capek; Stefan D Trocmé; Hamza Pasha; Humair Khan; Kevin H Merkley; Jong O. Lee; Ted Huang; David N Herndon; Hal K Hawkins

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 162. doi:

Results from 2016 National Survey of Children’s Health (NSCH)
Open Access

Sandra S Block; Kira Baldonado

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 163. doi:

The British Childhood Visual Impairment and Blindness Study 2 (BCVIS2) Open Access

Lucinda Teoh; Ameenat Solebo; Phillippa Cumberland; Jenefer Sargent; Jugnoo Rahi

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 164. doi:

UK & Ireland observational study of outcomes following congenital / infantile cataract surgery: IoLunder2 five year follow up Open Access

Ameenat Solebo; Phillippa Cumberland; Jugnoo Rahi

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 165. doi:

Five year epidemiologic review of pediatric cataracts managed at Children’s Hospital Los Angeles Open Access

Julia Johnston; Dilshad Contractor; Bibiana Jin Jin Reiser

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 166. doi:

The Swedish national paediatric cataract register (PECARE);
incidence and onset of post-operative glaucoma
Open Access

Gunilla Magnusson

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 167. doi:

Primary intraocular lens implantation in children under 12 months of age. Open Access

Emi Sanders; William F Astle

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 168. doi:

Pediatric Traumatic Cataract Complicated by Retinal Detachment Open Access

Howe Qiu; Nathan Fischer; Jennifer L Patnaik; Jennifer L Jung; Jasleen K Singh; Emily A McCourt

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 169. doi:

Incidence of Cytomegalovirus-Related Ocular Disease in Pediatric Patients Open Access

Carmel Mercado; Euna B Koo

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 170. doi:

Analysis of pattern and clinical features of pediatric uveitis cases at a tertiary referral center in São Paulo, Brazil Open Access

Barbara Giampietro; Fernanda Maria silveira Souto; Julia Thiemi Takiuti; Lucia Maria Arruda Campos; Carlos Eduardo Hirata; Joyce H Yamamoto

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 172. doi:

Clinical characteristics of children with Ahmed glaucoma valve implantation in a reference center in Mexico. Open Access

Alejandro Guerrero-León; Carlos Francisco Navas Villar; Janet Stephany Silva Ortiz; Curt Hartleben Matkin

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 174. doi:

Corneal Configurations and High Order Aberrations in Primary Congenital Glaucoma Open Access

Yin Hu; Lei Fang; Xiaohu Ding; Xinxing Guo; Xiao Yang; Xing Liu; Mingguang He

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 175. doi:

The effect of the history of delivery on the development of open-angle glaucoma. Open Access

jaeyeun lee; JoonMo Kim; Ki Ho Park

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 176. doi:

Ocular Findings in Osteogenesis Imperfecta: An Ophthalmologist Eye Survey Open Access

Felix Chau; Victor Villegas; Thasarat S Vajaranant; Irene H Maumenee

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 177. doi:

Classifying No Improvement in Visual Acuity in Children with Amblyopia Using Simulations Open Access

Rui Wu; Ruth E Manny; Michele Melia; Elizabeth Lazar; Jonathan M Holmes; Eileen E Birch; Susan A Cotter; Raymond Kraker; David K Wallace

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 178. doi:

Partial Tendon Recession for the Correction of Small-Angle Vertical Strabismus: Preliminary Results of a Comparative Case Series Open Access

Henry Lin; Andrew Reynolds

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 179. doi:

Cost analysis of a school-based vision program in Baltimore, MD Open Access

Alyssa M Kretz; Moneesha Rani Mukherjee; Niral B Ghandi; Robert Slavin; Nancy Madden; David S Friedman; Michael X Repka; Leana Wen; Gabriel Auteri; Evan Behrle; Kevin D Frick; Megan E Collins

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 181. doi:

Eyeglass retention in a school-based vision program Open Access

Moneesha Rani Mukherjee; Alyssa M Kretz; Xinxing Guo; Robert Slavin; Nancy Madden; David S Friedman; Michael X Repka; Evan Behrle; Leana Wen; Gabriel Auteri; Megan E Collins

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 182. doi:

Visual acuity assessment in children obtained using a novel cell phone application compared to the clinical examination in a pediatric ophthalmology clinic Open Access

Lloyd Zhao; Sandra Stinnett; Sasapin Grace Prakalapakorn

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 183. doi:

Sensitivity and Specificity of the Neonatal Red Reflex Open Access

Marco Vinicio Vinicio Víquez; Lihteh Wu

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 184. doi:

Prevalence of Eye Conditions in Children with a history of Postnatal Admission to Neonatal Intensive Care Units Open Access

Felicia Adinanto; Amanda French; Kathryn Ailsa Rose

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 185. doi:

Retinopathy of Prematurity in Rwanda: setting up a screening system. Open Access

Stefan Karel De Smedt

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 186. doi:

Longitudinal Analysis of Refractive Errors in Premature Children during the First Three Years of Life Open Access

Lauren Hennein; Alejandra de Alba Campomanes

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 187. doi:

Findings of Universal Newborn eye screening examination in South Korea – The results of five years. Open Access

So Young Kim

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 188. doi:

Characteristics of Birth-related retinal hemorrhages in Newborns. Open Access

Jungwoo Lee; So Young Kim

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 189. doi:

Montelukast modulates the NF-kB inflammatory cascade in mouse retinal endothelial cells
Open Access

Reena Malongil Bapputty; Ramaprasad Talahalli; Rose Anne Gubitosi-Klug

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 190. doi:

The protective effect of Liraglutide on retinal Müller cell apoptosis induced by high glucose through activating p-ERK / Nrf2 / Trx pathway Open Access

Xiang Ren; Ling min Sun; Jun li Liu; Li Kong

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 191. doi:

Ranibizumab or Aflibercept Therapy with Dexamethosone Intravitreal Injection Efficacy in Diabetic Macular Edema. Open Access

Joao J Nassaralla; Arthur A Nassaralla; Miguel Hage Amaro; Joao J Nassaralla

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 192. doi:

RETINAL BIOAVAILABILITY OF DIFFERENT CURCUMIN ORAL FORMULATIONS: A TRANSLATIONAL STUDY Open Access

Claudio Bucolo; Chiara B M Platania; Anna Fidilio; Francesca Lazzara; Cateno Piazza; Federica Geraci; Salvatore Salomone; Filippo Drago

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 193. doi:

Elevated Expression of AOC3 in Human Eyes with NPDR Open Access

Andreas Christian Borta; Oliver W Gramlich; Kimberly Miller; Cheyanne Godwin; Remko Bakker; Markus H Kuehn

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 194. doi:

Effects of multiple intravitreal anti-VEGF injections in a rabbit model of persistent retinal neovascularization (PRNV) Open Access

Yong Li; Joanna Marie Busoy; Ben Alfyan Achirn Zaman; Jay Ji-Ye Wei; Gavin Tan; Ning Cheung; Veluchamy A Barathi; Walter Hunziker; Wanjin Hong; Tien Yin Wong; Chui Ming Gemmy Cheung

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 195. doi:

Alpha-1 Antitrypsin Decreases Cx43 Expression Through PI3K/AKT Pathway in ARPE-19 Cells Exposed to High Glycemia Open Access

MARÍA CONSTANZA POTILINSKI; Gustavo Ortiz; Juan Pablo Salica; Emiliano López; Eduardo Chuluyán; Juan E Gallo

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 196. doi:

Systemic factors associated with choroidal thickness in eyes with diabetic retinopathy. Open Access

Jee Taek Kim; Min-Gyu Choi

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 197. doi:

ADX-103, a Novel Small Molecule Aldehyde Sequestering Agent, Decreases Retinal Edema and Inflammation in a Rat Model of Diabetic Macular Edema Open Access

Adna Halilovic; Todd Brady; Susan Macdonald

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 198. doi:

A VE-PTP Antibody Activates Tie2 and Suppresses VEGF-Induced Retinal Vascular Leakage Open Access

Kevin G Peters; Ji-kui Shen; Yuanyuan liu; Astrid Nottebaum; Dietmar Vestweber; Michael Flynn; Peter A Campochiaro

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 199. doi:

AR-13503 Enhances the Efficacy of Aflibercept in a Mouse Model of Proliferative Diabetic Retinopathy
Open Access

Kevin Carbajal; Meredith Weksler; Lori Moore; Jindong Ding; Casey Kopczynski; Cheng-Wen Lin

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 200. doi:

Alpha-1 Antitrypsin Decreases NFkB Signaling in Müller Cells in an in Vitro Diabetic Retinopathy Model. Open Access

Juan E Gallo; MARÍA CONSTANZA POTILINSKI; Gustavo Ortiz; Juan Pablo Salica; Emiliano López; Eduardo Chuluyán

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 201. doi:

Use Of Aflibercept (Zaltrap ZIV) in Diabetic Macular Edema Open Access

Efrain Romo-Garcia; Alonso Meza Anguiano; Silvia Paz Camacho; Gilberto Gutierrez; Wilehaldo Quiñonez

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 203. doi:

Recurrence of vitreous haemorrhage secondary to diabetic retinopathy in patients treated with intraoperative intravitreous Bevacizumab Open Access

ALEJANDRA Nieto Nieto Jordan; Alejandro Zermeno; Alejandro Ordonez Campos

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 204. doi:

ROCK/PKC Inhibitor AR-13503 Inhibits Angiogenesis and Protects the Barrier Function of Retinal Pigment Epithelium Open Access

Jindong Ding; Briana E Foley; Casey Kopczynski; Cheng-Wen Lin

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 205. doi:

Study on the effect of lutein in an experimental model of diabetic retinopathy using the Ins2Akita mice Open Access

Wei Wang; Amy CY Lo

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 206. doi:

Vitreous cytokine levels in proliferative diabetic retinopathy and cataracts Open Access

Jane Cho; Gyungah Jun; Thor Stein; Jaeyoon Chung; Kate McConnell; Marissa Fiorello; Steven Ness; Nicole Siegel; Manju Subramanian

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 207. doi:

A novel biologics platform extends half-life and improves tissue penetration of intravitreally injected biological agents Open Access

D. Victor Perlroth; Joel Naor; Wayne To; hong liang

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 209. doi:

KSI-301: An anti-VEGF antibody biopolymer conjugate with extended half-life for treatment of neovascular retinal diseases Open Access

hong liang; Xiaojian Huang; William Ngo; Dan Dang; Janine Lu; Rachel DeVay Jacobson; Ons Harrabi; D. Victor Perlroth

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 211. doi:

Superior stability of a class of novel antibody biopolymer conjugates for the treatment of retinal diseases Open Access

Amy Duguay; Wayne To; Jonathan Zhang; hong liang; D. Victor Perlroth; carrie Su

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 212. doi:

Re-packaging bevacizumab in 2-mL glass vials for prolonged sterility, stability and bio-activity Open Access

Jan S Peterson; Kenneth Rockwell; Paul C VanVeldhuisen; Michael S Ip; Ingrid U Scott; Barbara A Blodi

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 213. doi:

Role of Intravitreal Anti VEGF agents in the management of Tubercular choroidal and optic disc granulomas Open Access

Mohit Dogra; Ramandeep Singh

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 214. doi:

Reporting of safety events across anti-VEGF indications and the Pharmacovigilance approach: Findings from the non-interventional OCEAN study Open Access

Focke Ziemssen; Jessica Voegeler; Georg Spital; Sandra Liakopoulos; Steffen Schmitz-Valckenberg; Thomas Bertelmann

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 215. doi:

Retinal toxicity in rabbits administered intravitreal TSG-6-rabbit FAb fusion proteins Open Access

Steven Thomas Laing; Devin Tesar; Susan Crowell; Julia Gray; Kelly Loyet; Roxanne Andaya; Aija McKenzie; Florence Lorget; Bob Kelley

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 216. doi:

Effect of Ring Size on the Suitability of a New Class of Rho Kinase Compounds for Posterior Segment Disease Open Access

Mitchell A deLong; Jill Sturdivant; Cynthia Lichorowic; Cheng-Wen Lin; Casey Kopczynski

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 217. doi:

The CFTR corrector, VX-809 (Lumacaftor) and Hsp27 rescues ABCA4 trafficking mutants: a potential treatment for Stargardt disease Open Access

Liudmila Cebotaru; Qiangni Liu; Inna Sabirzhanova; Emily Bergbower; Murali Yanda; William Guggino

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 218. doi:

Development and characterization of a prototype antibody biopolymer conjugate targeting the complement system Open Access

Rachel DeVay Jacobson; Dan Dang; William Ngo; Janine Lu; Amy Duguay; Ons Harrabi; Xiaojian Huang; hong liang; D. Victor Perlroth

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 219. doi:

A novel approach to inhibit pro-angiogenic VEGF splicing in retinal vascular diseases with topical administration of small molecules optimised for retinal pharmacokinetics Open Access

Jennifer Batson; Hamish Toop; Susan Liddell; James Daubney; Elizabeth Stewart; Ken McKechnie; Jonathan Morris; David Bates

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 220. doi:

Sunitinib-Loaded Injectable Polymer Depot Formulation for Potential Once per Year Treatment of Neovascular Age-related Macular Degeneration (wet AMD) Open Access

Yun Yu; Ward Peterson; Ming Yang; David McKenzie; Delia Cardona; David Culp; Brian C Gilger; Jeffrey Cleland

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 221. doi:

microRNA-181a exhibits inhibitory effect on ocular neovascularization Open Access

Pierre Hardy; ChenRongRong Cai; Chun Yang; Stephane Croteau

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 222. doi:

Efficient choroidal neovascularization reduction by Sleeping Beauty Transposon-mediated PEDF gene delivery in rat iris and retinal pigment epithelial cells by using a clinical electropora... Open Access

Patricia Fernandez; Sergio Recalde; Maria Hernandez; Laura Garcia-Garcia; Jaione Bezunartea; Juan Roberto Rodriguez; Corinne Marie; Daniel Scherman; Zsuzsanna Izsvak; Martina Kropp; Sandra Johnen; Gabriele Thumann; Alfredo García-Layana

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 223. doi:

Efavirenz treatment reduces drusen-like lesions and choroidal neovascularization in the retina of 5XFAD mice, an Alzheimer’s disease model
Open Access

Irina A Pikuleva; Aicha Saadane; Nicole El-Darzi; Natalia Mast; George Trichonas

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 224. doi:

Activity of anti-Tissue Factor fusion protein ICON-1 in a swine model of choroidal neovascularization Open Access

William Greene; Grazia Spiga; Brian C Gilger; David Culp; Thi-Sau Migone

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 225. doi:

Stability and activity profiles of anti-complement factor D fragments translate across in vitro and in vivo studies to support long-acting delivery approaches Open Access

Kelly M Loyet; Philip Hass; Wendy Sandoval; Ashley Morando; Peter Liu; Whitney B Shatz; Leslie Dickmann; Margaret Kenrick; Jeremy Good; Teresa Davancaze; Alyssa Morimoto; Robert Kelley; Justin Scheer

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 226. doi:

Simulation of Ocular Drug Distribution Following Zero Order Release of Intravitreally Dosed Bevacizumab Using 3D Computational Fluid Dynamic Model
Open Access

Jie Shen; Mohammad Kazemi; Mayssa Attar

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 228. doi:

Ophthalmic Drug Delivery Using Injectable, Aqueous Driven, PEG/Vitamin E Copolymer Hydrogels Open Access

Lina Liu; Jianfeng Zhang; Heather Sheardown

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 229. doi:

Development of a Highly Bioavailable Nanocore-based (OcuSurf™) Ophthalmic Formulation for Treatment of Blepharitis
Open Access

Kevin Ward; Koushik Barman; Chinghong Li; Shikha P Barman

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 230. doi:

ICON-1 Pharmacokinetics after intravitreal and intravenous administration to rabbits Open Access

Gabriela Burian; Jacques Gaudreault; Brian C Gilger; David Culp; Thi-Sau Migone

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 231. doi:

Delivery and Toxicity of Ruthenium Pyridine-based Nanophotoswitches in Retina Open Access

Melanie Pribisko; Uli Herget; Lan Yue; Ming-yi Lin; Robert H Chow; Mark S. Humayun; Robert H Grubbs; Harry Gray

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 232. doi:

In Vitro and In Vivo Characterization of Abicipar Pegol, an anti-VEGF DARPin® Therapeutic Open Access

Gerry A Rodrigues; Matthew Mason; Lori-Ann Christie; Candice Hansen; James A Burke; Keith Luhrs; Thomas C Hohman

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 233. doi:

Peptides that Modulate Angiogenesis Open Access

Subrahmanian Tarakkad Krishnaji; Haojie Fu; Amy Birsner; Lauren Bazinet; Robert J D'Amato

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 234. doi:

Hyaluronic acid conjugation significantly extends the vitreal half-life of antibody fragments Open Access

Susan Crowell; Amin Famili; C. Andrew Boswell; Joyce Chan; Julia Gray; Kelly Loyet; Laetitia Comps-Agrar; Amrita kamath; Karthikan Rajagopal

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 235. doi:

Combining ISTH0036, an antisense oligonucleotide targeting Transforming Growth Factor beta 2 (TGF-β2) mRNA, with aflibercept as novel treatment strategy for neovascular retinal diseases Open Access

Michel Janicot; Giedrius Kalesnykas; Eugen Leo; Petra Fettes; Simon Kaja; Katja Wosikowski

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 236. doi:

Evaluation of the effects of VEGF/ANG-2 neutralization on vascular, neuronal and inflammatory pathologies in a spontaneous choroidal neovascularization (CNV) mouse model Open Access

Richard H Foxton; Sabine Uhles; Sabine Gruener; Franco Revelant; Nadine Colé; Mirjana Lazendic; Mathieu Brecheisen; Christoph Ullmer

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 237. doi:

Sustained Release of Small, Hydrophilic Peptides to the Ocular Surface via NanoM™
Open Access

Shikha P Barman; Yang Li; Laura Kaminski; Kevin Ward

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 238. doi:

Implementation of bioanalytical methods to quantify anti-VEGF-LAD (long acting delivery) Fabs in ocular matrices Open Access

Laetitia Comps-Agrar; Hilda Hernández-Barry; Joyce Chan; Keyang Xu; Luna Liu; Susan Crowell; Bob Kelley; Devin Tesar; Kelly Loyet

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 239. doi:

Delivery of anti-VEGF molecules via subconjunctival drug depots for back-of-the-eye diseases Open Access

Subbu Venkatraman; Rini Joseph; Hui Yee Chua; Gordon Minru Xiong

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 240. doi:

CHRONIC ORAL TREATMENT WITH BIO201 PRESERVES RETINAL FUNCTION IN A DRY AMD EXPERIMENTAL MODEL Open Access

Valerie Fontaine; Elodie Monteiro; Elena Brazhnikova; Mylene Fournie; Christine Balducci; Louis Guibout; Jose A. Sahel; Stanislas Veillet; Pierre Dilda; René Lafont

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 241. doi:

Ocular and Systemic Pharmacokinetics of a PEGylated-anti-Factor D Fab Multimer in Cynomolgous Monkeys Open Access

Daniela Bumbaca Yadav; Whitney B Shatz; danielle mandikian; C. Andrew Boswell; Aija McKenzie; Daniel Sheinson; Hong Liu; Isabel Figueroa; Bob Kelley; Devin Tesar; Michelle Dion; Amrita kamath; Florence Lorget; Susan Crowell

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 242. doi:

Identification and characterization of a novel protein-PEG conjugate system for long-acting delivery to the back of the eye Open Access

Whitney Shatz; Nikhil Peer; Philip Hass; Daniela Bumbaca; Kelly Loyet; Craig Blanchette; Robert Kelley

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 243. doi:

Pegylation of Abicipar Increases Vitreal Half-Life, Supporting a Potential for up to 3 Month Duration of Action in the Clinic Open Access

Jennifer Seal; Savira Ekawardhani; Anja Schlegel; Michael T Stumpp; H. Kaspar Binz; Mayssa Attar

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 244. doi:

Effectiveness of Sustained Release TKI Hydrogel Combined with Bevacizumab in a VEGF Induced Retinal Leakage Model Through 12 Months Open Access

Rami F Elhayek; Tim Jarrett; Zachary Lattrell; Erica Kahn; Stephen Takach; Jamie Lynne Metzinger; Michael H Goldstein; Peter K Jarrett; Amar Sawhney

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 245. doi:

PK/PD modeling to identify optimal binding affinity of an intravitreally administered anti-IL33 antibody to maintain target engagement in vitreous and retina for the treatment of AMD Open Access

isabel FIGUEROA; Gerald Nakamura; Laetitia Comps-Agrar; Joyce Chan; Elaine Mai; Racquel Corpuz; Jack Bevers; Kelly Loyet; Menno Van Lookeren Campagne; Amrita kamath

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 246. doi:

Clinical performance of multifocal scleral lens for presbyopia correction Open Access

Woo Park; Sang Wook Jin; Woo Jin Jeong; Long Yu Jin; Seon Tae Kim; Seung Yoon Noh; Seoung Hyun An

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 247. doi:

Clinical Outcomes Following Implantation of Extended Range of Vision 1-Piece Intraocular Lenses with Different Target Refraction and Diffractive Multifocal Intraocular Lenses with +2.75 D... Open Access

Youngsub Eom; Young Choi; Soo Youn Choi; Jae-hyung Kim; Ho Sik Hwang; Jun-Heon Kim; Jong Suk Song; Hyo Myung Kim

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 248. doi:

Comparison between simulated and clinical visual performance in pseudophakic patients with trifocal intraocular lens Open Access

Lin He; Srichand Jasti; Rajaraman Suryakumar; Ramesh Sarangapani

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 249. doi:

Visual performance of FineVision trifocal intraocular lens in refractive lens exchange surgery Open Access

Jaime Larrea Gonzalez; Luis Carlos Escaf; maria Isabel corrales; Virgilio Galvis; Alejandro Tello

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 250. doi:

Scleral Implants Improved Near Visual Acuity: A Subsample Analysis of Patients Treated for Presbyopia Open Access

Barbara Michalek; Frank A Bucci; Breanne Michalek

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 251. doi:

Comparison of multifocal visual simulations in patients before and after implantation of diffractive trifocal lenses Open Access

Maria Vinas; Mercedes Romero; Sara Aissati; Juan Luis Mendez-Gonzalez; Clara Benedi; Enrique Gambra; Vyas Akondi; nuria Garzon; Francisco Poyales; Carlos Dorronsoro; Susana Marcos

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 252. doi:

Factors influencing ametropia following toric intraocular lens implantation in eyes with high corneal astigmatism
Open Access

Chie Yukawa; Masaharu Iida; Keita Takada; Ryohei Nejima; Keiichiro Minami; Kazunori Miyata

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 253. doi:

Impact of residual astigmatism on optical and visual performance for toric intraocular lenses Open Access

Carmen Canovas; Patricia Piers; Mengchan Sun; Aixa Alarcon; Henk A Weeber; George Waring

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 254. doi:

Experimental optical analysis of an original presbyopia-correcting variable focus lens Open Access

Jessica Jarosz; Quentin Lavigne; Norbert Molliex; Guilhem Chenon; Guilllaume Noetinger; Duc-Duy Tran; Bruno Berge

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 255. doi:

Intraocular lens movement in different axial length Open Access

Manqiang Peng; Muhammad Ahmad Khan; xuetao Huang; Ding Lin

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 256. doi:

Point spread function and wavefront evaluation of IOLs with different amount of spherical aberration Open Access

Alice T Epitropoulos; Andrew Pilon; Valeri Kolesnitchenko

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 257. doi:

Simulated Vision of Patients with Multifocal Intraocular Lens by a New Mobile Model Eye. Open Access

Yong Ho Koo; Ho Sik Hwang

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 258. doi:

Assessment of Photic Phenomena for Five Monofocal IOL Models by Combining Model Eye and In Vitro Methods Open Access

Kamal Das; Liliana Werner; Stephan Collins; Xin Hong

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 260. doi:

In vitro evaluation of a novel extended depth of field intra-ocular lens design Open Access

Arthur Ho; James Panos; Klaus Ehrmann; Ian G Cox; Paul Erickson

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 261. doi:

Nanoscratch Evaluation of Various Hydrophobic Acrylic Intraocular Lens Materials in the Wet State Open Access

Andrew Pilon; Valeri Kolesnitchenko

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 262. doi:

Physical and chemical factors underlying glistening formation in hydrophobic acrylic intraocular lens materials Open Access

Kyoko Miura; Shin Sakai; Satoshi Yokota; Takahiro Tada; Shingo Katayama; Shinji Nagasaka; Tsutomu Sunada

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 263. doi:

Incidence of Negative Dysphotopsias with Plate-Shaped Collamer Intraocular Lenses
Open Access

Nicole Nikolic Bajic; Noah Simon; Kamran Riaz

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 264. doi:

In vitro assessment of longitudinal chromatic aberration in different optical designs of intraocular lenses Open Access

Grzegorz Łabuz; Son Hyeck-Soo; Timur Mert Yildirim; Gerd Auffarth

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 265. doi:

Optical Pathway Imaging and Straylight Evaluation of Opacified Intraocular Lenses Open Access

Hyeck Soo Son; Timur Mert Yildirim; Grzegorz Łabuz; Gerd Auffarth

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 266. doi:

Unfolding efficiency and time for optic recovery of a novel hydrophobic acrylic material as compared to currently available intraocular lens materials Open Access

Gary Guenthner; Madhu Ayyagari; Andrew Pilon; Valeri Kolesnitchenko

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 267. doi:

Full shape crystalline lens geometrical changes with age from 3-D OCT images in vivo and ex vivo Open Access

Eduardo Martinez-Enriquez; Ashik Mohamed; Marco Ruggeri; Miriam Velasco-Ocana; Siobhan Williams; Bianca Maceo Heilman; Alberto De Castro; Pablo Perez-Merino; N. Geetha Sravani,; Virender Sangwan; Jean-Marie A Parel; Robert C. Augusteyn; Arthur Ho; Fabrice Manns; Susana Marcos

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 268. doi:

Evaluation of vitreoretinal cellular infiltration in uveitis on optical coherence tomography Open Access

Wataru Matsumiya; Sentaro Kusuhara; Atsuko Katsuyama; Akihito Uji; Makoto Nakamura

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 269. doi:

Evaluation of Vitreous Cells Using Swept-Source Optical Coherence Tomography Open Access

Rene Choi; Yan Li; Jay Jyh-Kuen Siak; Chen Lu; ByungKun Lee; Jianlong Yang; Gangjun Liu; Eric B Suhler; Phoebe Lin; James G Fujimoto; James T. Rosenbaum; David Huang

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 270. doi:

Quantification of the tear film lipid layer using optical coherence tomography. Open Access

Valentin Aranha dos Santos; Leopold Schmetterer; Hannes Stegmann; Gerhard Garhofer; Doreen Schmidl; Rene Marcel Werkmeister

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 271. doi:

Topographical Profile of Peripapillary Choroidal Vascularity Index in Myopic Children Open Access

Ajay Kumar; Rupesh Agrawal; Neha Khandelwal; Daniel Bohan; Jody Paige Goh; Anne Goei; Janice Lam; Cheryl Ngo

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 272. doi:

Anterior Chamber Blood Cell Differentiation Using Spectroscopic Optical Coherence Tomography Open Access

Ruobing Qian; Ryan P McNabb; Anthony N Kuo; Joseph A. Izatt

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 273. doi:

Widefield Choroidal Thickness Distribution in Normal Eyes Open Access

Giovanni Gregori; Fang Zheng; Yingying Shi; Elie Motulsky; Philip J Rosenfeld

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 274. doi:

Vitreous visualization: a comparison between ultrasound and OCT widefield Open Access

Ugo Nava; Federico Corvi; Lucia Pace; salvatore parrulli; Matteo Giuseppe Cereda; Giovanni Staurenghi; Mariano Cozzi; Maria Belotti

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 275. doi:

Regional difference of choroidal structure by wide-field optical coherence tomography Open Access

Naoko Kakiuchi; Hiroto Terasaki; Shozo Sonoda; Hideki Shiihara; Taiji Sakamoto

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 276. doi:

Estimating retinal shape based on widefield optical coherence tomography and axial length measurements Open Access

Jochen Straub; Manuel Steidle; Conor Leahy; Simon Bello; Thomas Callan; Angie Covita

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 277. doi:

In vivo cellular resolution imaging of human retina with full-field OCT Open Access

Peng XIAO; Viacheslav Mazlin; Kate Grieve; Jose A. Sahel; Mathias Fink; Claude Boccara

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 278. doi:

Relation between IOP and air-puff-induced dynamics of ocular components in human eyes measured with full-eye-length SS-OCT Open Access

Ireneusz Grulkowski; Ewa Maczynska; Jagoda Rzeszewska; Alfonso Jimenez-Villar; Maciej Wojtkowski; Bartlomiej Kaluzny

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 279. doi:

Use of intraoperative optical coherence tomography in vitreoretinal surgery for dense vitreous hemorrhage in Chinese population Open Access

Jiwei Tao

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 280. doi:

Microstructural morphology in eyes with epiretinal membrane before, during and after membrane peeling in intraoperative optical coherence tomography (iOCT) and spectral domain OCT (SD-OCT... Open Access

Melanie Weschta; Moritz Pettenkofer; Nikolaus Feucht; Chris Patrick Lohmann; Mathias Maier

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 281. doi:

Peripheral vitreoretinal findings using intraoperative optical coherence tomography in rhegmatogenous retinal detachment Open Access

Koichi Nishitsuka; Akira Sugano; Hiroyuki Namba; Yutaka Kaneko; Katsuhiro Nishi; Hidetoshi Yamashita

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 282. doi:

Impact of Intraoperative OCT-Assisted Epiretinal Membrane Peeling on ERM Recurrence Rate Open Access

Steven Tran; Parisa Emami-naeini; Mustafa Safi; Senad Osmanovic; Ala Moshiri; Susanna S Park; Lawrence S Morse; Glenn Yiu

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 283. doi:

Axial Position-Based Colorization Improves Intraoperative Visualization of Live Volumetric (4D) Microscope-Integrated Optical Coherence Tomography (MIOCT) Open Access

Isaac Bleicher; Moseph Jackson-Atogi; Christian Viehland; Hesham Gabr; Joseph A. Izatt; Cynthia A Toth

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 284. doi:

Use of 3D printing technology in fabricating intraoperative OCT compatible ophthalmic tools Open Access

Hesham Gabr; Hoan Ngo; S. Tammy Hsu; Joseph Izatt; Cynthia A Toth

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 285. doi:

Feasibility of Intraocular Forward-Imaging B-scan Optical Coherence Tomography Probe to Guide Subretinal Injections Open Access

TOMAS A Moreno; Jin H Shen; Yuankai Tao; Karen M Joos

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 286. doi:

Injection Assistance via Surgical Needle Guidance using Microscope-Integrated OCT (MI-OCT) Open Access

Jakob Weiss; Nicola Rieke; M. Ali Nasseri; Mathias Maier; Chris Patrick Lohmann; Nassir Navab; Abouzar Eslami

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 287. doi:

Effects of multifocal and monofocal intraocular lenses on swept-source microscope-integrated optical coherence tomography (SS-MIOCT) image quality in a model eye. Open Access

Wenlan Zhang; James Tian; Ryan McNabb; Hoan Ngo; Christian Viehland; Anthony N Kuo; Joseph Izatt; Cynthia A Toth

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 288. doi:

In vivo multimodality ophthalmic imaging using surgical microscope-integrated intraoperative spectrally-encoded coherence tomography and reflectometry (iSECTR) Open Access

Mohamed El-Haddad; Joseph Malone; Kelsey C Leeburg; Benjamin D Terrones; Yuankai Tao

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 289. doi:

Subretinal fibrosis detection with polarization sensitive OCT Open Access

Maximilian G. O. Gräfe; Aleid van de Kreeke; Yvonne de Jong - Hesse; Frank D Verbraak; Johannes De boer

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 290. doi:

Polarization-sensitive swept-source OCT imaging of retinal pigment epithelium and subretinal fibrous tissues Open Access

Masahiro Yamanari; Mitsuhiro Matsuzaki; Seiji Takagi; Satoshi Sugiyama; Noriko Miyamoto; Yasuhiko Hirami; Naoshi Koide; Franck Jaillon; Daisuke Suzuki; Kota Totani; Kenji Horikoshi; SUSUMU OSHIMA; Michiko Mandai; Masayo Takahashi; Yasuo Kurimoto

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 291. doi:

In-vivo imaging of the healthy and pathological human limbus with 250 kHz, axicon lens-based, 1-µm axial resolution SD-OCT Open Access

Kostadinka K Bizheva; Zohreh Hosseinaee; Bingyao Tan; Han Le; Brian Ballios; Hall F. Chew; Allan Slomovic; Luigina Sorbara

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 293. doi:

Ex-vivo imaging of the posterior human corneal layers after Big Bubble DALK and DMEK procedures with sub-micrometer axial resolution OCT Open Access

Luigina Sorbara; Murad Al Obthani; Hall F. Chew; Zohreh Hosseinaee; Han Le; Cassandra Mary Maxwell; Denise Hileeto; Simon Holland; Clara Chan; Harminda Dua; Allan Slomovic; Kostadinka K Bizheva

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 294. doi:

Investigating the functional response of cone photoreceptors during bleaching and dark adaptation with 1.7MHz optical coherence tomography Open Access

Mehdi Azimipour; Justin V Migacz; Brennan Marsh-Armstrong; Kelly S Murrell; Robert J Zawadzki; Ravi Sankar Jonnal; John S Werner

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 295. doi:

Capturing fine retinal structure using adaptive optics optical coherence tomography (AOOCT) with real-time retinal tracking Open Access

Koji Nozato; Kohei Takeno; Makoto Fukuhara; Kazuhiro Matsumoto; Yuji Katashiba; Hiroyoshi Tanaka; Hiroyuki Inoue; Yasuhisa Inao; Yuzo Sato; Hideyuki Ooban; Keisuke Oyaizu; Hayato Shioda; Hiroshi Aoki; Takashi Yuasa; Tomoyuki Makihira

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 296. doi:

Compact retinal optical coherence tomography instrument at 1060nm for large field of view imaging including an optical zoom in option using adaptive optics Open Access

Matthias Salas; Marco Augustin; Franz Felberer; Laurin Gabriel Ginner; Andreas Wartak; Rainer Leitgeb; Xavier Levecq; Adrian Reumüller; Andreas Pollreisz; Ursula Schmidt-Erfurth; Wolfgang Drexler; Michael Pircher

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 297. doi:

Increasing the field of view in high resolution imaging of the retina with adaptive optics optical coherence tomography Open Access

Michael Pircher; Marie Laslandes; Matthias Salas; Andreas Wartak; Christoph K Hitzenberger

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 298. doi:

Achromatized visible light OCT for ultrahigh resolution retinal imaging Open Access

Tingwei Zhang; Shau Poh Poh Chong; Aaron Michael Kho; Marcel Bernucci; Alfredo Dubra; Vivek Jay Srinivasan

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 299. doi:

Imaging motion in the retina in 3D using FF-SS-OCT Open Access

Gereon Huttmann; Hendrik Spahr; Clara Pfäffle; Dierck Hillmann

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 300. doi:

Optical coherence tomography angiography of choriocapillaris: normative macular choriocapillaris vasculature and novel classification of early-stage systemic hypertensive changes: A cross... Open Access

Kei Takayama; Yasuki Ito; Hiroki Kaneko; Keiko Kataoka; Takeshi Iwase; Taichi Tsunekawa; Hideyuki Shimizu; Ayana Suzumura; Tomohiko Akahori; Hiroko Terasaki

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 302. doi:

Evaluation of the subfoveal choroidal thickness in patients with oculocutaneous albinism. Open Access

MARCO SANTOS ALMEIDA; Liara Hirota; Roberta Pereira de Almeida Manzano; Ronaldo Yuiti Sano

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 303. doi:

RPE-specific Sox9 controls dorsal choroidal vascular development in the mouse retina Open Access

So Goto; Akishi Onishi; Yoko Ohigashi; Hirokazu Sakaguchi; Kohji Nishida; Masayo Takahashi

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 304. doi:

Relativity of choroidal thickness and blood flow in the subfoveal area with Idiopathic Macular Hole Open Access

lin qiurong; Haiyun Liu

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 305. doi:

Morphological Changes of the Retinal Choroid in Severe Alzheimer’s Disease: A Histopathological Study Open Access

Fred N. Ross-Cisneros; Samuel Asanad; Ernesto Barron; Alec Chan Golston; Eric A Barron; Alfredo A Sadun

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 306. doi:

Histopathologic Validation of Choroidal Thickness as a Biomarker for Leber's Hereditary Optic Neuropathy (LHON) Open Access

Fei Lin; Samuel Asanad; Fatemeh Darvizeh; Fred N. Ross-Cisneros; Mario Schunimann; Piero Barboni; Alfredo A Sadun

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 307. doi:

Morphological classification of RALDH2-positive cells in the human choroid Open Access

Falk Schroedl; Alexandra Kaser-Eichberger; Andrea Trost; Christian Runge; Daniela Bruckner; Barbara Bogner; Clemens Strohmaier; Herbert A Reitsamer; Jody A Summers

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 308. doi:

Comparison of TGF-β stimulated optic nerve head astrocytes in 2D versus 3D cultures Open Access

Kathryn E Bollinger; Barbara Mysona; jing zhao; Cecelia Hernandez; Graydon Gonsalvez

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 309. doi:

Understanding the role of glial cells (astrocytes and oligodendrocytes) in maintaining the homeostasis of the optic nerve Open Access

Meysam Yazdankhah; Rhonda Grebe; Emily G Baxi; Imran Ahmed Bhutto; Stacey L Hose; Amanda N. FairchildBaranowski; Peter Calabresi; J. Samuel Zigler; Debasish Sinha

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 311. doi:

Novel characterization of Prox-1 expression in the optic nerve Open Access

Yujia Yang; Liwei Zhang; Guangyu Li; Lu Chen

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 312. doi:

Synaptic coupling of unmyelinated optic nerve axons – a novel insight into optic nerve structure and conductivity properties Open Access

Adrian Smedowski; Saeed Akhtar; Lucia Podracka; Xiaonan Liu; Elisa Toropainen; Marialaura Amadio; Marita Pietrucha-Dutczak; Markku Varjosalo; Arto Urtti; Kai Kaarniranta; Joanna Lewin-Kowalik

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 313. doi:

Development of a Porcine Optic Nerve Injury Model Open Access

Drew Holt; Elaine Por; Jeffery Cleland; Jason Harris; Vijay Gorantla; Melody Sandoval; Chiquita Thomas-Benson; Lekrystal Harris; Alden Negaard; Larry I. Benowitz; Jeffrey L Goldberg; Gregory T Bramblett

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 314. doi:

Intra-optic nerve delivery of AAV-mediated gene therapy in mice Open Access

Joseph Paul; Timothy Colgan; Vicki Chrysostomou; Peter van Wijngaarden; Jonathan G Crowston

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 315. doi:

SEAM Organoids Model Iris Muscle Cell Development from the Optic Cup Open Access

Bar Nachmani; Timothy A Blenkinsop

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 318. doi:

Developmental change in the gene-expression of transient receptor potential melanostatin channel 3 (TRPM3) in murine lacrimal gland
Open Access

Anna Kanewska; Masataka Ito; Yoko Karasawa; Makoto Inada; Fabian Garreis; Friedrich P Paulsen; Masaru Takeuchi

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 319. doi:

Tracking Mesenchyme Primordial Cells with Gli1 Labeled the Optic Nerve Head and Periocular Mesenchyme Open Access

Kathy K H Svoboda; Hu Zhao; Matthew Petroll

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 320. doi:

Lactate receptor GPR81 modulates the integrated stress response in the developing outer retina Open Access

Xiaojuan Yang; Raphael Rouget; Tang Zhu; Christiane Quiniou; Francois Duhamel; José Carlos Rivera; Pierre Lachapelle; Sylvain Chemtob

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 321. doi:

FGF and WNT Signaling Pathways Synergize During Ciliary Margin Development Open Access

Revathi Balasubramanian; Chenqi Tao; Karina Polanco; Xin Zhang

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 322. doi:

p190RhoGAP is Required for Proper Temporal Completion of Chroid Fissure Closure in the Zebrafish Eye Open Access

Andrea James

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 323. doi:

Identification of a Conserved Biophysical Mechanism for Productive Eye Repair Open Access

Taylor Birkholz; Cindy Kha; Wendy Beane; Kelly Ai-Sun Tseng

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 324. doi:

Generation of a Novel Peroxidasin Knockout Mouse Open Access

Xiaohe Yan; Dali Li; Hongbo Cheng

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 325. doi:

NIDOGEN: A LYNCHPIN OF BASEMENT MEMBRANE DISASSEMBLY PRIOR TO CHOROID FISSURE FUSION. Open Access

Nicholas Carrara; Jakub Famulski

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 326. doi:

Postnatal development of the nonhuman primate fovea is modulated by breast versus formula feeding Open Access

Martha Neuringer; Trevor J McGill; Emily E Johnson; Kasie Paul; John W Erdman; Matthew Kuchan; Lauren Renner

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 327. doi:

Molecular genetic investigation of two distinct monogenic disorders with ocular involvement in a large consanguineous Roma family Open Access

Lubica Dudakova; Pavlina Skalicka; Petra Liskova

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 328. doi:

Tissue artefacts in post mortem human eyes. Open Access

Svetlana Cherepanoff; Lay Khoon Too; Victoria Pye; Murray Killingsworth; Alex Allende; Alessandro Invernizzi; Alex Hunyor; James Wong; Jennifer Arnold; Rohan Merani; Michael Rodriguez; Michele C Madigan; Geoff Hall

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 330. doi:

A cadaveric study of periocular and orbital surgical anatomy Open Access

Luke Dolezal; Veren Rana; Jason Sokol

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 331. doi:

Multi-electrode recording as a novel technique in electromyography of the orbicularis oculi muscle Open Access

Bonnie Sklar; Kalla A Gervasio; Khushmit Kaur; Mark Sivak; Albert Wu

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 332. doi:

Single particle tracking of nicotinic acetylcholine receptors (AChRs): implication for the pathogenesis of ocular myasthenia gravis (MG) Open Access

Wei He; Yang Sun

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 333. doi:

Feasibility of detecting RNA expression in human vitreous Open Access

Michelle Peng; Kornwipa Hemarat; Qingyun Liu; Xiangbin Kong; Intira Sukpen; Max Kudish; James Lo; Diego Tapas; Catherine Chia; Jacquelyn Kemmer; Ariana Naaseh; Thuy Doan; Ricardo Lamy; Jay M Stewart

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 334. doi:

The role of prostaglandins in floppy eyelid syndrome. Open Access

Brittany Simmons; Tailun Zhao; Collynn Woeller; Mithra Gonzalez

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 335. doi:

Measurement and analysis of pH in human vitreous body Open Access

Hiroki Mieno; Kentaro Kojima; Kazuhito Yoneda; Kenji Nagata; Tohru Inaba; Yoshinori Marunaka; Chie Sotozono

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 336. doi:

From observations in the retina clinic to insights into pathophysiology Open Access

Artur V Cideciyan

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 338. doi:

From observations in the retina clinic to insights into pathophysiology Open Access

Samuel G Jacobson

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 339. doi:

What Escher and Bach teach us about Immunology Open Access

Reza Dana

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 340. doi:

Altered mitochondrial homeostasis with AMD progression Open Access

Jorge Ricardo Polanco; Rebecca J Kapphahn; Sandra Rocio Montezuma; Deborah A. Ferrington

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 341. doi:

Visual Cycle Proteins Increase Acutely After Stimulation with CSE Open Access

Marisol del Valle Cano; Roma Pegany; Joshua Ocasio; Audrey Collins; Sayantan Datta; Lei Wang; tongyun Liu; Sonny Dike; James T Handa

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 342. doi:

Copper triggers mitochondrial biogenesis and helps in survival of RPE
Open Access

Bharathidevi Subramaniam Rajesh; Aloysius Dhivya Manohar; Sulochana KN

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 343. doi:

The role of interleukin-33 in retinal tissue fibrosis after laser injury Open Access

KEISUKE ADACHI; Toshiaki Hirakata; Yosuke Asada; Satoshi Iwamoto; Susumu Nakae; Akira Matsuda

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 344. doi:

Effects of oxidative stress and AMD on mitochondrial homeostasis in cultured human primary RPE Open Access

Cody Ronald Fisher; Mara Supik; Sandra Rocio Montezuma; Deborah A. Ferrington

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 345. doi:

The pathogenesis of polypoidal choroidal vasculopathy proceeds via a two-stage process Open Access

Yingbin Fu; Sandeep Kumar; Hiroyuki Nakashizuka; Alex Jones; Alyssia Lambert; Xuchen Zhao; Megan Shen; Mackenzie Parker; Mark O M Tso; Jon Rainier

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 346. doi:

The reduction of XIAP is associated with NLRP3 inflammasome activation in RPE: implications for AMD pathogenesis Open Access

Jiangyuan Gao; Haohang Rachel Chen; Sijia Cao; Jing Z Cui; Aikun Wang; Joanne A Matsubara

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 347. doi:

Dietary Cholesterol Contributes to Vision Loss in a Complement-Dysregulated AMD Mouse Model
Open Access

Michael Landowski; Una L Kelly; Daniel Grigsby; Marybeth Groelle; Catherine Bowes Rickman

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 348. doi:

Cytokine profiling in patients with exudative age-related macular degeneration due to choroidal neovascularization and polypoidal choroidal vasculopathy Open Access

Xin Wei; Praveen Kumar Balne; Veonice Bijin Au; Bernett Lee; Neha Khandelwal; John Connolly; Raja Narayanan; Swaminathan Sethu; Rupesh Agrawal

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 349. doi:

Relationship between pachychoroid and aqueous humor concentrations of inflammatory cytokines in age-related macular degeneration Open Access

Masatoshi Onda; Hidenori Takahashi; Yuji Inoue; Xue Tan; Yusuke Arai; Ryota Takahashi; Satoru Inoda; Shinichi Sakamoto; Ichiya Sano; Yujiro Fujino; Hidetoshi Kawashima; Yasuo Yanagi

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 350. doi:

Preventive effects of (-)-epicatechin on retina and pigmented epithelium impaired by sodium iodate (NaIO₃) Open Access

Bani Antonio-Aguirre; Luis Enrique Niembro-Muñoz; Xavier P Guillonneau; Israel Ramirez-Sanchez; Andric Christopher Perez-Ortiz; Alvaro Rendon; Esmeralda Lira-Romero; Lidia Elena Llacsahuanga-Allcca; Martha Janneth Peralta-Ildefonso; David Jimenez-Collado; Francisco Javier Estrada-Mena

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 351. doi:

Modulation of microRNA: Implications for macular degeneration Open Access

Kevin Schneider; Marilyn Chwa; Mehrnoosh Saghizadeh; Cristina M Kenney

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 353. doi:

Carboxyvinylpyrrole Protein Adducts: Potential AMD Biomarkers Open Access

Geeng-Fu Jang; Jack Crabb; belinda Willard; Joe G Hollyfield; Robert Salomon; John W Crabb

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 354. doi:

Glucose-6-Phosphate Dehydrogenase (G6PD) deficiency and age-related macular degeneration in a Sardinian male population, Italy Open Access

Ermete Giancipoli; Giuseppe D'Amico Ricci; Tiziana Porcu; Ciriaco Carru; Francesco Boscia; Antonio Pinna

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 355. doi:

Analysis of the Aqueous Humor Proteome in Patients with Age-related Macular Degeneration Open Access

Itay Chowers; Gala Beykin; Liran Tiosano; Samer Khateb; Sarah Hayoun; Michelle Grunin; Shira Levi; Batya Rinsky

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 356. doi:

Synergistic cytotoxicity and genotoxicity of polycyclic aromatic hydrocarbons and blue light in retinal pigment epithelium cells Open Access

Corinne Zinflou; Patrick J Rochette

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 357. doi:

A negative feedback loop between Angiogenin and Telomerase in AMD pathogenesis Open Access

Anuprita Ghosh; Swaminathan Sethu; Ganesh Ram Sahu; santosh gopi krishna gadde; Naresh Kumar Yadav; Rupesh Agrawal; Debasish Sinha; Arkasubhra Ghosh

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 358. doi:

c-Jun mediated microRNA-302d-3p induces RPE dedifferentiation and CNV formation by targeting p21^Waf1/Cip1 Open Access

Xue Chen; chao jiang; Chen Zhao

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 359. doi:

Cigarette smoke oxidant, hydroquinone, downregulates p62 and Nrf2 protein expressions in human RPE and induces cell death Open Access

Samuel Abokyi; Chi-ho To; Samantha Sze Wan SHAN; Henry Ho-lung Chan; Dennis Tse

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 361. doi:

EVA1A/TMEM166 regulates choroidal neovascularization by autophagy Open Access

Luzhen Huang

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 362. doi:

Photo-conversion of A2E by high-energy visible light Open Access

Marie-Christine Lambert; Mathieu Ouellette; Elodie Boisselier; Patrick J Rochette

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 363. doi:

Enhanced Detection of Sub-Retinal Pigment Epithelial Cell Layer Deposits in Human and Murine Tissue with New Zinc Detecting Probes Open Access

Scott W McPherson; Heidi Roehrich; Subrata Ghosh; Krishnakanth Sada; Mangili Venkateswarulu; Erik J Van Kuijk

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 364. doi:

Repressed AMP- activated protein kinase, Sirtuin1 and peroxisome proliferator-activated receptor-gamma coactivator (PGC)-1alpha, overactive mammalian target of rapamycin, and dysregulated... Open Access

Nady Golestaneh; Nisi Jiang; Olga Postnikova; Amrita Cheema

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 365. doi:

A Mechanism study toward understanding the protective effects of glutaredoxin 2 (Grx2) on light-induced retinal damage Open Access

Xiaobin Liu; Christy Xavier; Duen-Shian Wang; Princess Ananti; Yang Liu; Hongli Wu

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 366. doi:

Biochemical analysis of mutations in transmembrane domain one of ABCA4 responsible for Stargardt Macular Degeneration Open Access

Fabian Garces; Robert S Molday

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 367. doi:

Protective effect of unbleachable retinal chromophore analogue against light-induced retinal degeneration in mice
Open Access

Beata Jastrzebska; Songqi Gao; Grazyna Palczewska; Marcin Golczak; Zhigian Dong; Krzysztof Palczewski

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 369. doi:

Epigenetic disease mechanisms associated with age-related macular degeneration Open Access

Freekje Van Asten; Ximena Corso Diaz; Vijender Chaitankar; Rinki Ratnapriya; Margaret Starostik; Emily Y. Chew; Deborah A. Ferrington; Anand Swaroop

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 370. doi:

Aqueous humour metabolic profiles in typical age-related macular degeneration and polypoidal choroidal vasculopathy Open Access

Yasuo Yanagi; Yan Gao; Lei Zhou; Hidenori Takahashi; Yujiro Fujino; Hidetoshi Kawashima; Roger W. Beuerman; Tien Yin Wong

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 371. doi:

Loss of NLRP1 Inflammasome Exacerbated Retinal Photoreceptor Damage and Choroidal Neovascularization in Mouse Models of Age-related Macular Degeneration through Reduction of IL-18 Open Access

Jiawei Ren; Xian Zhang; QIUPING LIU; Qianyan Kang; Jingming Li

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 372. doi:

Ferroptosis in human retinal pigment epithelial cells induced by oxidative stress. Open Access

kiyohito Totsuka; Takashi Ueta; Takatoshi Uchida; Suguru Nakagawa; MEGUMI HONJO; Makoto Aihara

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 373. doi:

CRISPR/Cas9 Targeted Disruption of Herpes Simplex Virus type 1 in a Rabbit Latency Model Reduces Viral Reactivation and Associated Corneal Pathology Open Access

Christopher M Owens; Benjamin Diner; Robert Fusco; Emily King; Ari Friedland; Pankhuri Singhal; Kiran Gogi; Fred Harbinski; Shen Shen; Michael Stefanidakis; Luis Barrera; David Bumcrot; Donna Neumann; Charlie Albright

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 374. doi:

Analysis of CEP78 knockout in zebrafish generated by CRISPR-Cas9 Open Access

Yael Kinarty; Samer Khateb; Dror Sharon; Adi Inbal

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 375. doi:

Gene and mutation independent therapy via CRISPR-Cas9 mediated cellular reprogramming in rod photoreceptors Open Access

Jie Zhu; Xin Fu; Chang Ming; Yaou Duan; Duc Anh Hoang; Runze Zhang; Jeffrey Rutgard; Daniel Zhang; Rui Hou; Wenjun Xiong; Kang Zhang

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 376. doi:

CRISPR/Cas9 mediated knockout of rcbtb1 in Xenopus tropicalis to model RCBTB1-associated retinal disease Open Access

Giulia Ascari; Thomas Naert; Tom Van Nieuwenhuysen; Suzan Demuynck; Chris Guerin; Frauke Coppieters; Kris Vleminckx; Elfride De Baere

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 377. doi:

RHODOPSIN transcriptional silencing & replacement for the treatment of autosomal dominant Retinitis Pigmentosa Open Access

Enrico Maria Surace; Salvatore Botta; Elena Marrocco; Nicola de Prisco; Martina Sofia; Mariangela Lupo; Carlo Gesualdo; Settimio Rossi; Francesca Simonelli

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 378. doi:

A Novel Hammerhead Ribozyme with High Catalytic Activity at Physiological Free Mg²⁺ Levels: A Potential Therapeutic for Autosomal Dominant Retinitis Pigmentosa Open Access

Jason Myers; Zahra Fayazi; Mark Christian Butler; Jack M Sullivan

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 380. doi:

Should Genomic Expression Constructs be Employed when Developing Post-Transcriptional Silencing Agents for Gene Therapies? Open Access

Alexandria J Trujillo; Jack M Sullivan

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 381. doi:

Validation of Staphylococcus aureus Cas9 gRNAs targeting EGFP present in the rod cells of the Nrl-EGFP mouse line. Open Access

Caroline Peddle; Robert E MacLaren; Michelle McClements

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 382. doi:

ASNIP CRISPR - A novel personalised medicine approach to treat autosomal disease Open Access

Kathleen Christie; Larry A. DeDionisio; Connie Chao Shern; Kevin Blighe; M. Andrew Nesbit; Tara CB Moore

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 383. doi:

Efficient in vivo editing of CEP290 IVS26 by EDIT-101 as a novel therapeutic for treatment of Leber Congenital Amaurosis 10 Open Access

Michael Stefanidakis; Morgan Maeder; George Bounoutas; Clifford Yudkoff; Hoson Chao; Scott Haskett; Delena Nguyen; Steven J Samuelsson; Georgia Giannoukos; Dawn Ciulla; Eugenio Marco; Christopher Wilson; Peter Baciu; Pam Stetkiewicz; Charlie Albright; Haiyan Jiang

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 385. doi:

withdrawn - Normal Retinal Phenotype in the Aged Global Cas9 Expressing Mouse Strain Open Access

Mark Ellsworth Kleinman; Kyung Sik Jung; Sushil Dubey

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 386. doi:

Outcome After ≥6 Intravitreal Dexamethasone Implants For Macular Edema Due To Retinal Vein Occlusion Open Access

Muna Bhende; Smriti Jain; Yamini Attiku; Rajiv Raman

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 387. doi:

Aquaporin 4 and glymphatic drainage in the human macula Open Access

Francine F Behar-Cohen; Alexandre Moulin; Laurent Jonet; Emmanuelle Gelize; Alexandre Sellam; Patricia Crisanti

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 388. doi:

Anti-vascular endothelial growth factor agents reduce inflammation in central retinal vein occlusion with macular edema Open Access

Hidetaka Noma; Kanako Yasuda; Masahiko Shimura

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 389. doi:

Intravitreal Dexamethasone Implant Migration into the Anterior Chamber: A Multicenter Study from the Pan-American Collaborative Retina Study Group Open Access

Mariana Batista Gonçalves; Bruno Queiroz Alves; Raphael Moura; Octaviano Magalhães Júnior; André Maia; Rubens Belfort Jr; Marcos Ávila; Marcelo Zas; Mario J Saravia; Marcia Lousas; Lihteh Wu; J Fernando Arevalo; Katia Delalibera Pacheco; Michel Eid Farah; Francisco J Rodriguez; Mauricio Maia

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 390. doi:

Establishing a Colony of Non-human Primates with Cystoid Macular Edema Open Access

Laura Belen; Kortni Violette; Christopher Schillo; Christopher Gallotta; Christian Grant; Leslie Jost; David Hollander; Andy Whitlock

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 391. doi:

Prospective study of the morphologic and functional parameter changes post treatment of macular oedema associated with different retinal disorders Open Access

Lazha Sharief; Yi-Hsing Chen; Susan Lightman; Oren Tomkins-Netzer

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 392. doi:

12 Month follow-up of Intraocular Pressure after Ozurdex Implantation: a retrospective analysis
Open Access

Michael Ellis; Lawrence S Morse; Susanna S Park; Glenn Yiu; Ala Moshiri

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 393. doi:

Preoperative Intraocular Dexamethasone Implant for Treatment of Macular Edema Prior to Cataract Surgery Open Access

Himanshu Banda; Bradley T Smith

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 394. doi:

Electroretinography after long-term follow-up of selective retina therapy for macular edema.
Open Access

Satoshi Honda; Manabu Yamamoto; Takeya Kohno; Kumiko Hirayama; Akika Kyo; Dirk Theissen-Kunde; Yoko Miura; Ralf Brinkmann; Kunihiko Shiraki

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 395. doi:

The incidence of increased intraocular pressure and glaucoma incisional surgery following treatment with dexamethasone intravitreal implant in a private practice setting Open Access

Rim Makhlouf; Jay Levy; Rashid Taher; Diana Shechtman; Ava K Bittner

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 396. doi:

Results of Aflibercept in Hispanics with retinal vein occlusion macular edema Open Access

Francisco J Rodriguez; Shirley Margarita Rosenstiehl; Diana Alejandra Cortes; Claudia Rosa Carvajal

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 397. doi:

Best corrected visual acuity(BCVA) and central macular thickness (CMT) outcomes after fluocinolone acetonide intravitreal implant (FAc) injection in multitreated chronic diabetic macular ... Open Access

Manuel Paez; Eric William Deupree; Michael John Tolentino; Dana Madison Deupree

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 398. doi:

Effect of Tobacco Use on the Efficacy of Intravitreal Injection of Bevacizumab in Patients with Diabetic Macular Edema (DME) Open Access

Oliver G Fischer; David Scott Ketner

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 399. doi:

Clinical factors associated with response to dexamethasone intravitreal implant in DME recalcitrant to bevacizumab. Open Access

Pradeep Prasad; Diana Lee; Michael Javaheri

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 400. doi:

Ultrawide field scanning laser ophthalmoscopy imaging in macular edema Open Access

Radwan Ajlan; Luke Barnard; Ashley Small

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 401. doi:

The SD-OCT and OCT-A profile of DRIL extension in cases of diabetic macular edema refractory to anti-VEGF Open Access

Miguel Nicolas Nicolás Cruz Pimentel; Daniel Mesa Rosselló; Audrey Juan; Nassim Abreu Arbaje; Yazmín Baéz; Jeannette Domínguez; Juan F Batlle Pichardo; Lihteh Wu

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 402. doi:

A systematic review of the effectiveness of pharmacological agents for the treatment of uveitic macular oedema (UMO) Open Access

Mohammad O S Tallouzi; Robert John Barry; David J Moore; Melanie J Calvert; Philip Ian Murray; Jonathan M Mathers; Alastair K Denniston

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 403. doi:

Efficacy of adalimumab for refractory noninfectious uveitis in Australia Open Access

Jonathan Tak Loong Lee; William Yates; Sophie Rogers; Denis Wakefield; Peter J McCluskey; Lyndell L Lim

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 404. doi:

Adalimumab for the treatment of uveitis in a Japanese population Open Access

Yosuke Harada; Yoshiaki Kiuchi

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 405. doi:

Infliximab for the successful treatment of uveitis failing adalimumab. Open Access

Noy Ashkenazy; Ujwala Saboo; Ashley Abraham; Cristiana Ronconi; Graham Kuizin; Jennifer Cao

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 406. doi:

Tumor necrosis factor inhibitors improve inflammatory control in eyes with refractory non-infectious uveitis. Open Access

Ahmed Al-Janabi; Amgad El Nokrashy; Lazha Sharief; Susan Lightman; Oren Tomkins-Netzer

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 407. doi:

Methotrexate and tumor necrosis factor- α inhibitors discontinuation in pediatric non-infectious uveitis Open Access

Sheila T Angeles-Han; Courtney McCracken; Steven Yeh; Kirsten Jenkins; Curtis Travers; Kelly A. Rouster-Stevens; Scott R. Lambert; Carolyn Drews-Botsch; Sampath Prahalad

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 408. doi:

Title: Efficacy of abatacept treatment for severe, recalcitrant pediatric uveitis
Open Access

Syeda Maryam Ahmed Naqvi; Virginia Miraldi Utz; Sabrina Bulas; Lovell Dan; Sarah Lopper; Adam H. Kaufman

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 409. doi:

Effects of Vitreomacular Adhesion on Treatment Outcomes in the Study of Safety and Bioactivity of TOcilizumab in Patients with Non-Infectious UVEITIS: The STOP-UVEITIS Study Open Access

Nam V Nguyen; Muhammad Hassan; Muhammad Sohail Halim; Rubbia Afridi; Sean Baluyot; Yasir Jamal Sepah

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 410. doi:

Interferon Alpha-2a: an effective therapeutic option in patients with refractory uveitic cystoid macular edema
Open Access

Luca Cimino; Luca De Simone; Raffaella Aldigeri; Valentina Mastrofilippo; Sylvia Marchi; Anna Sangiovanni; Luigi Fontana; Carlo Salvarani

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 411. doi:

Post-Hoc Comparison of Best-Corrected Visual Acuity Improvement in Study and Untreated Fellow Eyes with Active Non-Infectious Uveitis of the Posterior Segment in the SAKURA Program Open Access

Brian C Joondeph

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 413. doi:

Pharmacokinetics of Sirolimus in Subjects Treated with Intravitreal Sirolimus in the SAVE-2 Study: Sirolimus As Therapeutic Approach to UVEitis – Protocol 2 with Two Doses of Intravitreal... Open Access

Yasir Jamal Sepah; Diana V Do; Hitomi Takanaga; Sreenivasu Mudumba; Quan Dong Nguyen

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 415. doi:

Treatment of noninfectious intermediate uveitis with dexamethasone (Ozurdex) intravitreal implant. Open Access

Christopher Welsh; Solin Saleh; Chloe Gottlieb

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 416. doi:

Dissociations of the fluocinolone acetonide implant: experience from long-term follow-up during the Multicenter Uveitis Steroid Treatment (MUST) Trial and Follow-up Study Open Access

Elizabeth A Sugar; Janet A Holbrook; Alyce E Burke; Glenn J Jaffe; Albert T Vitale; Janet L. Davis; Douglas A Jabs

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 417. doi:

Controlling Posterior Segment Uveitic Recurrences: Results from a Phase 3 Study of 0.18 mg Fluocinolone Acetonide Intravitreal Insert (FAi) in Subjects with Chronic Non-Infectious Uveitis... Open Access

Quan Dong Nguyen; Keyur Patel; Dario A Paggiarino

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 418. doi:

Injectable 0.19 mg fluocinolone acetonide (FAc) intravitreal implant for the treatment of non-infectious uveitic macular edema – a retrospective case study analysis Open Access

Ramin Khoramnia; Lea Weber; Stefanie Marx; Alexander Scheuerle; Gerd Auffarth

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 419. doi:

Are Anti-angiogenics (Bevacizumab) Intravitreal Injections as Effective as Intravitreal Triamcinolone Acetonide Injections for the Management of Persistent Non-infectious Uveitic Cystoid ... Open Access

J Fernando Arevalo; Andres F Lasave; Bernardo Ariel Schlaen; David Zeballos; Manuel Díaz-Llopis; Cristobal Avelino Couto; Wael El-Haig

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 420. doi:

Association between nonsteroidal anti-inflammatory drugs and uveitis recurrence in ankylosing spondylitis patients Open Access

Kaidi Wang; Lianne Gensler; Andrew Hirst; John D Reveille; Michael M Ward; Michael H Weisman; Matthew A Brown; MinJae Lee; Mohammad Rahbar; Travis Porco; Nisha Acharya

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 421. doi:

Suclinical signs persistance in Vogt-Koyanagi-Harada disease (VKHD) patients treated with early high-dose corticosteroids and immunosuppressive therapy (IMT) Open Access

Marcelo Mendes Lavezzo; Viviane Mayumi Sakata; Ever Ernesto Caso Rodriguez; Smairah Frutuoso Abdallah; Cintia Kanenobu; Celso Morita; Maria Kiyoko Oyamada; Carlos Eduardo Hirata; Joyce H Yamamoto

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 422. doi:

Immunosuppressants and/or Anti-Vascular Endothelial Growth Factor inhibitors in Punctate Inner Choroidopathy?
Follow-up Results with Optical Coherence Tomography Angiography Open Access

Dominika Pohlmann; Uwe Pleyer; Antonia M Joussen; Sibylle Winterhalter

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 423. doi:

Treatment of Relentless Placoid Choroidopathy with Intravenous Cyclophosphamide: A case series Open Access

Alejandro Zermeno; Ricardo Moreno

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 424. doi:

A retrospective study for scleritis therapy with immunosupressant and biological agents Open Access

Noriko Oishi; Satoko Yui; Naka Shiratori; Junko Hori

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 425. doi:

Long-term Maintenance Therapy of Rituximab in Treatment of Noninfectious Scleritis Open Access

Swetha Dhanireddy; Robert Swan; C. Stephen Foster

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 426. doi:

Repository Corticotropin Injection (RCI) in Ocular Inflammation: A Case Series and Literature Review Open Access

Alexander B Crane; Yael Sharon; David S. Chu

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 427. doi:

Sutureless Intrascleral Intraocular Lens Fixation Using a Microtube-assisted Technique Open Access

Kentaro Yuda; Toshiki Shimizu; Takahiko Hayashi; Kenji Yuda

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 428. doi:

The effect of OASIS iris expander in phacoemulsification surgery of cataract with small pupil Open Access

Jing Shang Zhang; Jin Da Wang; Xiu Hua Wan

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 429. doi:

Reliability of IOL Master 700 biometry readings in eyes with dense cataracts Open Access

John Wong; Philemon Huang; Han Bor Fam

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 430. doi:

Evaluation and Comparison of Macular and Choroidal Thickness after Intracameral Moxifloxacin for Prevention of Postcataract Endophthalmitis Open Access

Bruna Gil Ferreira; Iuri Cardoso da Silva; Matheus Ivan S. Vieira; Monica Alves; Mathias Violante Mélega; Alex Treiger Grupenmacher; Maurício Abujamra Nascimento; Rodrigo P. C. Lira; Carlos Eduardo L. Arieta

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 431. doi:

Is Trypan blue capsular staining really safe in cataract surgery? Open Access

Young Min Park; Jong Moon Park; Sung Who Park; Jong Soo Lee

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 432. doi:

Does the Use of a Preloaded Intraocular Lens Delivery System Improve Post-operative Refractive Outcomes for Cataract Surgery? Open Access

Mary Henry; Nishal Patel

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 433. doi:

Practice Patterns of Canadian Ophthalmological Society members in Cataract Surgery - Survey 2017 Open Access

Dara Onasanya; Lindsay Ong-Tone

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 434. doi:

Efficacy of optic capture without anterior vitrectomy in pediatric cataract surgery Open Access

Akiko Iwata; Shunji Kusaka; Kuniko Tachibana; Kosuke Abe; Daishi Tsujioka; Yoshikazu Shimomura

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 435. doi:

Diagnostic signs and biometric characteristics for preexisting posterior capsule defects in congenital cataracts during the first year of life
Open Access

Yun-e Zhao; Zhangliang Li; pingjun chang; Xixia Ding; Yinying Zhao

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 436. doi:

Electron microscopy studies for opacified Intraocular lenses after glaucoma tube implants Open Access

Ahmed Abdelmaksoud; Rebecca Lace; Simon Romani; Karl Dawson; Rachel Williams; Sarah Bentley; Mark Batterbury; Anna Bhargava

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 437. doi:

Femtosecond laser-assisted cataract surgery in octo and nonagenerians. Open Access

Priya Nidamanuri; Magdalena Popiela; Bushra Thajudeen; Vinod Kumar

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 438. doi:

Motion capture of capsulorhexis forceps Open Access

András Bálint; Balázs Varsányi; Zsolt Biró

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 439. doi:

Accuracy of partial coherence interferometry in patients with large inter-eye axial length difference Open Access

Christine Ann Petersen; Parisa Taravati; Philip P Chen

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 440. doi:

Phacoemulsification: subluxation versus divide and conquer in Beginner Surgeon Open Access

lakehal-ayat youcef; Christophe Goetz; George Hayek; Marie-Soline LUC; Jean-Charles Vermion; Nadia Ouamara; Jean-Marc Perone

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 441. doi:

Long-term Outcomes for Pediatric Patients Undergoing Trans-Scleral Fixation of the Capsular Bag with Intraocular Lens for Ectopia Lentis Open Access

Leah Owen; Julia Byrd; Marielle Young; Wei Liu; David Tate; Yue Zhang; Alan S Crandall

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 442. doi:

Opacification of Scleral Sutured Hydrophilic Acrylic Intraocular Lenses in Patients with Subsequent DSAEK or Pars Plana Vitrectomy Open Access

Tatyana Beketova; Gene Kim

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 443. doi:

Accuracy of new postoperative ACD prediction formula using anterior segment OCT Open Access

Hiroshi Sasaki; Hidetoshi Ishida; Aya Ii; Mai Kita; Yusuke Seki; Naoko Shibata; Hisanori Miyashita; Eri Shibuya; Norihiro Mita; Eri Kubo

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 444. doi:

Comparison of Corneal Endothelial Cell Changes after Phacoemulsification using Different Viscosurgical Devices
Open Access

Hongyan Zhang; Mozhu Li; Xudong Song; Hongxin Song

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 445. doi:

Surgical Simulator Training Techniques to Teach Residents Capsular Rhexis with the Non-Dominant Hand Open Access

Stephen Dryden; Jason Jensen; Elliott Kanner

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 447. doi:

Comparison of intraocular pressure (IOP) lowering effect of Femtosecond Laser Assisted Cataract Surgery (FLACS) as compared to conventional phacoemulsification Open Access

Erin Ong; Sharon Ong; Luke Chang; Syed Karim; Arturo Betancourt; Brad Spagnolo; Andrew Hammer; Osamah Saeedi

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 448. doi:

The Effect of Phacoemulsification on Intraocular Pressure in Glaucoma Patients in Resident Cases Open Access

Zoey Stoumbos; Deborah Wilson

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 449. doi:

Glaucoma surgery & ocular surface. Open Access

Rodrigo M Torres

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 450. doi:

Effects of trabeculectomy on optical characteristics Open Access

YU MIZUNO; Yoshiaki Kiuchi

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 451. doi:

Evaluation of cataract progression after trabeculectomy using lens densitometry by Pentacam Scheimpflug imaging and lens thickness by A-scan ultrasound
Open Access

Johanna Orphal; Karin R Pillunat; Robert Herber; Lutz E Pillunat

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 452. doi:

Combined Cataract and Glaucoma Surgery using a Dual Blade and Direct Viscodilation of the Collector Channels Open Access

Linda Burk; Jane Gilmore

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 453. doi:

Reducing long-term complications after combined cataract, lens implant and trabeculectomy surgeries. Open Access

Edward J Rockwood

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 454. doi:

Quality improvement: where is gonioscopy? Open Access

Beatrice Des Marchais; Elianne De Larochellière; Ralph Kyrillos; Milime Keyeutat Tondji

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 456. doi:

Effect of combined phacoemulsification and goniotomy on intraocular pressure in open-angle glaucoma Open Access

Chang-Sik Kim; Woo-Jin Kim; Woo-Hyuk Lee; Kyung-Nam Kim

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 457. doi:

Gonioscopy-assisted Transluminal Trabeculotomy (GATT) outcomes in eyes with treatment resistant open angle glaucoma. Open Access

Carlos Matos Neto; Marco Antonio Rey de Faria; Gabriela de Sousa Martins Melo de Araujo; Rafael Barbosa de Araujo; Bruno Mendes de Faria

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 458. doi:

Intraocular pressure reduction after combined ab interno trabeculotomy and endocyclophotocoagulation in patients with open angle glaucoma Open Access

Louisa Lu; Ji Liu

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 459. doi:

Relationship between intraocular pressure reduction and visual field aggravation after trabeculectomy in eyes with open angle glaucoma Open Access

SHUNSUKE TAKAHASHI; Akira Sawada; Tetsuya Yamamoto

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 460. doi:

Changes in choroidal area after intraocular pressure reduction following trabeculectomy Open Access

Kazuyuki Hirooka; Hirokazu Kojima; Eri Nitta; Kaori Ukegawa; Shozo Sonoda; Taiji Sakamoto

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 461. doi:

Comparison of changes in mGCIPL thickness between medically and surgically treated eyes with advanced glaucoma Open Access

Masahiro Onda; Akira Sawada; Hiroko Inuzuka; Tetsuya Yamamoto

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 462. doi:

Ocular Axial Length as an Indicator of Success in the Control of Primary Congenital Glaucoma (PCG) in Children Undergoing Early Trabeculotomy Open Access

Ana Catarina Melo; Artur C Veloso; Sebastiao Cronemberger; Nassim S Calixto; Eduardo Milhomens

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 464. doi:

High-stakes ocular surgery through the eyes of the surgeon: Experiences of operating on ‘only-eye’ patients. Open Access

Lee Jones; Vinette Cross; David P Crabb; Peter Shah

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 465. doi:

Ten year, single surgeon, series of 'Moorfields safer surgery technique' trabeculectomy, and combined phacotrabeculectomy with IOL: a 'Medisoft' EPR audit from Gloucestershire, UK Open Access

Andrew Ian McNaught; David Crabb

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 466. doi:

Outcomes of trabectome and phaco-trabectome by glaucoma severity: experience in a
reference center in Mexico. Open Access

Carlos Francisco Navas Villar; Janet Stephany Silva Ortiz; Curt Hartleben Matkin

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 467. doi:

Trabeculectomy bleb morphology – type of antimetabolite and other predictive factors for the development of adverse thin cystic blebs Open Access

Toby Al-Mugheiry; David C Broadway

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 468. doi:

Structural Assessment of Filtering Blebs in Eyes Requiring Digital Compression. A Comparative Study using a Clinical and Tomographic Approach. Open Access

Yesenia Yolanda Dorantes Diez; Jose A Paczka; Marco Cuadros; Montserrat Romo Sainz; Miguel Angel Dorantes-Diez

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 469. doi:

Small-incision revision of trabeculectomy with mitomycin: outcomes and complications
Open Access

Philip P Chen; Kristy Moeller

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 470. doi:

Subconjuctival Injection Versus Direct Scleral Application of Mitomycin-C in Trabeculectomy Open Access

Jiun Do; Benjamin Xu; Andrew Camp; Philip Ngai; Robert N Weinreb

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 471. doi:

Sponge-Applied vs Subconjunctival Injection of Mitomycin-C during Phaco-Trabeculectomy in Asian Eyes Open Access

Xiner Guo; Bryan Ang; Peck Hoon Angela Lim; Boon Ang Lim; Vernon Yong; Hon Tym Wong; Leonard Wei Leon Yip

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 472. doi:

Nonpenetrating Deep Sclerectomy with Mitomycin C: 5 Year Follow-up with analysis of IOP control and Visual Field Survival Open Access

Grant Slagle; William Eric Sponsel

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 473. doi:

A Novel Decorin and SAHA Combination Therapy to Treat Bleb Fibrosis in Vivo in Rabbits Open Access

Jella Angela An; Suneel Gupta; Michael K Fink; Nathan Hesemann; Ratnakar Tripathi; Prashant R Sinha; Lindsey McDaniel; Rajiv R Mohan

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 474. doi:

Antifibrotic effect of conbercept (KH902) on human tenon’s fibroblasts Open Access

Shaodan Zhang; Lin Du; Di Wu; WAI KIT CHU; Hailin Wang; Chi Liu

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 476. doi:

Valproic Acid Reduces Inflammation following Experimental Glaucoma Surgery Open Access

Tina Wong; Li Zhen Toh; Stephanie Chu; Li Fong Seet

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 477. doi:

Inhibitory effects of Y-27632, Rho-associated protein kinase inhibitor, on scarring formation following glaucoma filtration surgery Open Access

Diah Gemala Ibrahim; Ji-Ae Ko; Wakana Iwata; Hideaki Okumichi; Yoshiaki Kiuchi

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 478. doi:

Assessing the effects of indomethacin and dexamethasone on wound healing using a 3D bioartificial tissue of human Tenon’s capsule fibroblasts Open Access

Jim Denstedt; James Armstrong; Cindy ML Hutnik; Charles Trelford

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 479. doi:

Novel characterization and intravital imaging of dynamic conjunctival lymphangiogenesis after filtration surgery Open Access

Miao Zhang; Guangyu Li; Meng Shi; Lu Chen

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 480. doi:

Outcomes of microcatheter-assisted trabeculotomy in the treatment of primary congenital glaucoma after failed glaucoma surgeries
Open Access

huaizhou wang; Man Hu; Yan Shi; Ningli Wang

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 481. doi:

Number of postoperative follow-up visits after phacoemulsification in glaucoma and nonglaucoma patients Open Access

Priscilla Nobrega; Karine Bojikian; Philip P Chen

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 482. doi:

Histologic Analysis of Trabecular Meshwork Obtained from Kahook Dual Blade Goniotomy Open Access

Swarup Sai Swaminathan; Pedro Monsalve; Mabel Enriquez-Algeciras; Xiao Yi Zhou; Sanjoy K Bhattacharya; Sander R Dubovy; Anna K Junk

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 483. doi:

Influence of incision arc amount of trabecular meshwork on the short-term outcome of gonioscopy-assisted transluminal trabeculotomy/suture-trabeculotomy ab interno Open Access

Kazuhiko Mori; Yuji Yamamoto; Yoko Ikeda; Morio Ueno; Kojiro Imai; Chie Sotozono

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 484. doi:

Sutureless scleral tunnel trabeculectomy, case series report. Open Access

Clarisa Esther Del Hierro; Luis Laneri Pusineri; Carolina Prado-Larrea; Rafael Castañeda; Jesus Jimenez Roman

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 485. doi:

Variability of tensile strength during microsurgical knot construction: A comparative study of polyglactin 910 and lactomer suture Open Access

Abayomi Fabunmi; Douglas Rhee

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 486. doi:

Post-operative complications after non-valved glaucoma device implantation due to rapid Polysorb^TM suture absorption time. Open Access

Dante Sorrentino; Ian Conner; Julia Polat

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 487. doi:

Biodegradable Material for Glaucoma Drainage Devices – A Pilot study in Rabbits Open Access

SIMAR RAJAN SINGH; Surinder Singh Pandav; Ritambhra Nada; Sushmita Kaushik

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 488. doi:

Early Experience with Gonioscopy-Assisted Transluminal Trabeculotomy (GATT) using Poly-Propylene Suture in Patients with Open Angle Glaucoma Open Access

maria Isabel corrales; Marco Cuadros; Virgilio Galvis; Jose A Paczka

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 489. doi:

The Effect of Smoking on Trabeculectomy Outcomes Open Access

Jonathan Young; Ross Passo; Beth Edmunds; John C Morrison; Hana Takusagawa; Shandiz Tehrani

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 490. doi:

Effect of Tobacco Smoking on Outcomes of Trabeculectomy Open Access

Nadia Rios Acosta; Lisa Gould; Jennifer Rahman; Gdih Gdih; Shveta Bali

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 491. doi:

A Rabbit Model for Glaucoma Filtration Surgery Open Access

Saumya Nagar; Alexandra Almazan; Lakshmi Rajagopalan; Susan S Lee; Werhner Orilla; James A Burke; Michael R Robinson

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 492. doi:

The alteration of gene expression profiles after filtration surgery in mouse
Open Access

Akira Matsuda; Yosuke Asada; Satoshi Iwamoto

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 493. doi:

Role of TSLP in mediation of Toll-like receptor2/4 and antimicrobial peptides in innate immunity of corneal A. fumigatus infection
Open Access

Chenyang Dai; Xinyi Wu

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 494. doi:

TSLP-activated dendritic cells induce T helper type 2 inflammation in Aspergillus fumigatus keratitis
Open Access

Lin Sun; Xinyi Wu

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 495. doi:

In Vitro Susceptibility of Intravitreal Fungal Endophthalmitis Isolates to Novel Antifungal Agents Open Access

Kenneth Chen Fan; Jonathan Foster Russell; Darlene Miller; Harry W Flynn

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 498. doi:

Gene Expression Changes in Human Retinal Pigment Epithelial (hRPE) Cells Following Infection with Toxoplasma gondii Open Access

Elise Rochet; Shervi Lie; Yuefang Ma; Liam M. Ashander; Audra M. A. Shadforth; Timothy A. Blenkinsop; Binoy Appukuttan; Beth Wilmot; Justine R. Smith

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 499. doi:

Efficacy of Nanosponges in Protecting Retinal Function During Bacterial Endophthalmitis Open Access

Michelle C Callegan; Phillip S Coburn; Frederick Christian Miller; Austin L LaGrow; Craig Land; Yijie Chen; Weiwei Gao; Liangfang Zhang

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 500. doi:

In vivo imaging of Pseudomonas aeruginosa gene expression on mouse contact lenses Open Access

Melinda Rose Grosser; Matteo Metruccio; Lauren Tabor; David J Evans; Suzanne M J Fleiszig

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 501. doi:

The role of corneal lymphangiogenesis in a murine bacterial keratitis model. Open Access

Akitomo Narimatsu; Takaaki Hattori; Naoto Koike; Kazuki Tajima; Hayate Nakagawa; Marina Ogawa; Shigeto Kumakura; Tetsuya Matsumoto; Hiroshi Goto

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 502. doi:

L -2-amino-4-methoxy-trans-3-butenoic acid Production by the Keratitis Associated Pseudomonas aeruginosa Open Access

Salina E. Salamah; Michael Kovach; Rachida Bouhenni

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 503. doi:

IQ-domain GTPase-activating protein1 (IQGAP-1) Modulation of Tight Junction Proteins and Protection against P. aeruginosa Invasion
Open Access

Elizabeth P Shen; Fung-Rong Hu

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 504. doi:

Contact lens wear can trigger clandestine parainflammation in mice. Open Access

Suzanne M J Fleiszig; Matteo Metruccio; Aaron Sullivan; Abby Kroken; Hart Horneman; Stephanie Wan; David J Evans

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 505. doi:

Microscopic characterization of mouse model mixed keratitis Open Access

Diana Gabriela Ponce-Angulo; Luis Antonio Bautista-Hernández; Rosa Paulina Calvillo-Medina; Gerardo Aparicio-Ozores; Rosa María Ribas-Jaimes; Victor Manuel Bautista

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 506. doi:

Experimental immune-mediated conjunctivitis (EIC): downregulation by Coversin, a dual C5 and LTB4 inhibitor
Open Access

Virginia Calder; Malihe Eskandarpour; Xiaozhe Zhang; Yi-Hsing Chen; Miles Nunn; Wynne Weston-Davies

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 507. doi:

Combined blockade of VEGFR-3 and Itga-9 promotes lamellar corneal transplant survival
Open Access

Meng Shi; Ziya Zhang; Guangyu Li; Yasuyuki Yokosaki; David G. Hwang; Lu Chen

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 508. doi:

Expression of T cell/transmembrane, immunoglobulin, and mucin (TIM)-4 in normal cornea and corneal grafts Open Access

Ayaka Takeda; Hiroko Taniguchi; Tomoyuki Kunishige; Hisaya Akiba; Hideo Yagita; Junko Hori

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 510. doi:

Immunophenotypic profiles of inflammatory cells in chalazion.
Open Access

Rei Nemoto; Yoshihiko Usui; Shunichiro Ueda; Hiroshi Goto

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 511. doi:

CRISPR/Cas9-Mediated Genome Editing of Herpesviruses Limits Productive and Latent Infections Open Access

Saskia Imhof

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 512. doi:

Heparanase upregulation in human corneal tissues infected with herpes simplex virus type 1 Open Access

Ann-Marie Lobo; Deepak Shukla

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 513. doi:

The absense of DHHC3 affects primary and latent HSV-1 infection Open Access

Shaohui Wang; Kevin Mott; Marianne Cilluffo; Casey Kilpatrick; Shoko Murakami; Alexander V Ljubimov; Konstantin G. Kousoulas; Sita Awasthi; Bernhard Luscher; Homayon Ghiasi

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 514. doi:

Effect of recombinant HSV-1 expressing IL-4 or IFN-γ on macrophage responses in vitro and in vivo Open Access

Dhong Hyun Lee; Homayon Ghiasi

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 515. doi:

A Surprising Failure of Herpes Simplex Virus Type 1 (HSV-1) to Spread to the Brain or Contralateral Retina Following Uniocular Inoculation of Mice with Retrovirus-induced Immunosuppressio... Open Access

Madeline Welch; Jessica Carter; Lauren Duncan; Jay Oh; Richard D Dix

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 516. doi:

The NLRP3 Inflammasome is Involved in the Pathogenesis of Experimental Murine Cytomegalovirus (MCMV) Retinitis in Mice with Retrovirus-induced Immunosuppression (MAIDS) Open Access

Jessica Carter; Jay Oh; Lauren Duncan; Madeline Welch; Max Housman; Richard D Dix

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 517. doi:

Hypoxia associated glycolytic reprogramming in the pathogenesis of herpes stromal keratitis (HSK) Open Access

Susmit Suvas; Pushpa Rao

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 518. doi:

Human HSV-Specific Memory CD8⁺ T_EM Cells with Unique JAK/STAT, Chemokine and Anti-Inflammatory Gene Signatures Are Associated with Asymptomatic Ocular Herpes Infection Open Access

Lbachir BenMohamed; Hawa Vahed; Ruchi Srivastava; Anthony B Nesburn

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 519. doi:

Blockade of Lymphocyte activation gene-3 (LAG-3) Pathway Improved the Size and Protective Function of Herpes Simplex Virus-Specific CD8⁺ T cells against Ocular Herpes Infection and Diseas... Open Access

Anthony B Nesburn; Ruchi Srivastava; Roy Soumyabrata; Lbachir BenMohamed

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 520. doi:

Network modeling of proteins identifies critical sites for vaccine design Open Access

Elizabeth Rossin; James Chodosh; Bruce Walker; Gaurav Gaiha

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 521. doi:

Molecular mechanisms of corneal collagen crosslinking Open Access

Guzel Bikbova; Azat Khalimov; Gyulli Kazakbaeva; Mukharram Bikbov

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 522. doi:

Phenotypic study of PAX6 haploinsufficient aniridic corneal stromal cells in a tissue equivalent Open Access

Carla Sanchez Martinez; Victoria Tovell; Stephen J. Tuft; Julie T Daniels

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 523. doi:

Corneal biomechanics following intrastromal injection of hyaluronidase Open Access

Soohyun Kim; Iman Jalilian; Vijay Krishna Raghunathan; Sara M Thomasy; Christopher J Murphy

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 524. doi:

Plasminogen promotes phagocytic activity of cultured human corneal fibroblasts Open Access

Tomoko Sato; Koji Sugioka; Junko Murakami; Hiroshi Mishima; Teruo Nishida; Yoshikazu Shimomura

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 525. doi:

Improvement of Keratoprosthesis Biointegration by Covalent Functionalization of PMMA Open Access

Roholah Sharifi; Mohammad Mirazul Islam; Soudabe Mahmoudzadeh; James Chodosh; Claes H Dohlman; Miguel Gonzalez-Andrades

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 526. doi:

3D engineered corneal stroma-derived cells on a laser-assisted bioprinted matrix Open Access

Richard Nagymihaly; Anni Sorkio; Lothar Koch; Morten Carstens Moe; Boris Chichkov; Heli Skottman; Goran Petrovski

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 527. doi:

Collagenolytic Properties of Staphylococcus Aureus culture broth and Staphylokinase on Human Corneal Fibroblasts Cultured in Collagen Gel
Open Access

Koji Sugioka; Aya Kodama-Takahashi; Tomoko Sato; Junko Murakami; Hiroshi Mishima; Teruo Nishida; Yoshikazu Shimomura

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 528. doi:

Corneal Changes in Patients Treated with Rose Bengal Photodynamic Antimicrobial Therapy for Severe Infectious Keratitis Open Access

Jaime D. Martinez; Sander R Dubovy; Guillermo Amescua; Pedro Monsalve; Xiao Yi Zhou; Alejandro Arboleda; Heather Ann Durkee; Mariela C Aguilar; Nidhi Relhan; Neda Nikpoor; Harry W Flynn; Darlene Miller; Jean-Marie A Parel

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 529. doi:

Stimulation of cell proliferation and collagen synthesis of human corneal stromal cells in vitro for regeneration of ocular surface Open Access

Meike Hasenzahl; Stephan Reichl

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 530. doi:

Generation of primary pluripotent spheroid culture from human corneas using human platelet lysates Open Access

Jingjing You; Hannah Elizabeth Frazer; Li Wen; Simon Cooper; Chris Hodge; Gerard Sutton

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 531. doi:

A novel tissue engineered corneal stromal equivalent Open Access

Xin Che; Changkai Jia; Han Wu; Shangkun Ou; Xin He; Wei Li

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 532. doi:

Identification of the function of keratocan positive keratocytes Open Access

Ting Su; Xueting Chen; Xulin Liao; Zheng Wan; Yunpeng Li; Winston W Y Kao; Wei Li; Yongxiong Chen; Zuguo Liu

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 534. doi:

Enhancement of Constructing Ultra-thin Corneal Stromal Membranes-Based Bioengineered Retinal Pigment Epithelial Sheet in iPS - Conditioned Medium Open Access

Jianing Gu; Yini Wang; Xin Yan; Xu Yang; Hu Huang; Heping Xu; Jiansu Chen; Shibo Tang

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 536. doi:

Direct-to-consumer marketing by U.S. Stem-Cell Clinics for Ocular Conditions Open Access

Rajinder Singh Nirwan; Thomas Arno Albini; Jayanth Sridhar; Harry W Flynn; Ajay E. Kuriyan

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 537. doi:

Evaluation of cell production and shipment procedure in non-human primates for hESC-RPE sheet transplantation Open Access

Tanja Ilmarinen; Heidi Hongisto; Zengping Liu; Edmund Yick Mun Wong; Roger W. Beuerman; Gavin Tan; Boris V. Stanzel; Heli Skottman

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 538. doi:

HLA-E-Expressing “Universal” Pluripotent Stem Cells as a Source of Retinal Pigment Epithelium to Treat Age-Related Macular Degeneration Open Access

mei jiang; Marta Stevanovic; Vanda Lopes; Biju Thomas; David Russell; Mark S. Humayun; Dennis O Clegg

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 539. doi:

Mesenchymal stem cells reduce neuroretinal degeneration in vitro Open Access

Ivan Fernandez-Bueno; Sonia Labrador; Maria Teresa Garcia-Gutierrez; Girish Kumar Srivastava; Jose-Carlos Pastor

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 540. doi:

Genetical modification to reduce bipolar cells in hESC derived retinas aiming for enhanced host-graft contact after transplantation Open Access

Suguru Yamasaki; Tomoyo Hashiguchi; Takehito Watanabe; Keizo Matsushita; Atsushi Kuwahara; Akiyoshi Kishino; Toru Kimura; Masayo Takahashi; Michiko Mandai

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 541. doi:

Defining the optimal stage for transplantation of pluripotent stem cell derived photoreceptor precursors
Open Access

DARIN ZERTI; Joseph Collin; David Steel; Carla Bernadette Mellough; Evelyne Sernagor; Lyle Armstrong; Majlinda Lako

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 542. doi:

Comprehensive in vivo assessment of human pluripotent stem cell-derived photoreceptor survival and differentiation potential in the immune-compromised S334ter rat Open Access

Joe Phillips; Allison Ludwig; Patrick Barney; Katherine Barlow; Lindsey Jager; Elizabeth E Capowski; David M Gamm

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 543. doi:

3D retina organoids produced from CRX-GFP human embryonic stem cells (hESCs) processed into retinal sheets and transplanted into immunodeficient retinal degenerate (RD) rats Open Access

Magdalene J Seiler; Bryce T McLelland; Joseph Collin; Carla Bernadette Mellough; Majlinda Lako; Robert B Aramant; Gabriel Nistor; Hans S Keirstead

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 544. doi:

Subretinal transplantation of human induced pluripotent stem cell-derived retinal pigment epithelium (hiPS-RPE) into pigs.
Open Access

Dirk Sandner; Marlene Stein; Dierk Wittig; Seba Almedawar; Helmut Sachs; Martin Scharffenberg; Roland Jung; Lutz Pillunat; Elly Tanaka; Mike O. Karl; Marius Ader

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 545. doi:

Efficacy of clinical-grade iPSC-RPE cells and patch in rodent and swine models of retinal degeneration Open Access

Aaron Rising; Vladimir Khristov; Yichao Li; Maria M Campos; Haohua Qian; Jonathan Stoddard; Arvydas Maminishkis; Juan Amaral; Trevor J McGill; Sheldon S Miller; Kapil Bharti

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 546. doi:

Stem cell therapy for treatment of ischemic optic neuropathy Open Access

Louise Alessandra Mesentier-Louro; Nan Yang; Ali Shariati; Pablo Daniel Domizi; Robert Dodd; Gerlinde Wernig; Marius Wernig; Yaping Joyce Liao

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 549. doi:

Mesenchymal stromal cells promote vascular regeneration and modulate inflammation in a mouse model of ischemic retinopathy Open Access

Baraa Noueihed; Jose Carlos Rivera; Sylvain Chemtob

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 550. doi:

Validating the efficacy of GMP-NPCs following subretinal injection into an animal model of retinal degeneration Open Access

Bin Lu; Sergey Girman; Changqing Zhang; Joshua Saylor; Alice Pieplow; Sean Ghiam; Benjamin Bakondi; Amanda Block; Laura Nocito-Labad; Alexander V Ljubimov; Clive N Svendsen; Shaomei Wang

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 551. doi:

Modulation of the inner limiting membrane to enhance cellular engraftment into the ganglion cell layer Open Access

Zenith Acosta Torres; Galina Dvoriantchikova; Dmitry V Ivanov; Daniel Pelaez

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 552. doi:

Objective quantification of photoreceptor ribbon synapses in iPS cell-derived retina after transplantation to retinal degeneration model mice Open Access

Ryutaro Akiba; Takesi Matsuyama Hoyos; Michiko Mandai; Shuichi Yamamoto; Masayo Takahashi

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 553. doi:

The secretome of adipose stem cells primed for TSG-6 expression protects retinal endothelial barrier function and suppresses microglial activation Open Access

Mickey Pentecost; Kumar Abhiram Jha; Lada Klaic; Alex Beland; RAJI RAJESH LENIN; Nicolas Sohl; James Wohlschlegel; Rajashekhar Gangaraju

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 554. doi:

AMD Cell Therapy Efficacy Assessment Using Artificial Intelligence-Based Multi-Spectral Imaging Open Access

Nathan Hotaling; Nicholas J Schaub; Qin Wan; Ruchi Sharma; Sarala Padi; Petre Manescu; Joe Chalfoun; Mylene Simon; Mohamed Ouladi; Carl G. Simon; Peter Bajcsy; Kapil Bharti

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 555. doi:

Towards macular regeneration: generation, MACS purification and transplantation of cone photoreceptors derived from mouse induced pluripotent stem cells (mIPSC). Open Access

Hany Abdelgawad; Jeayoung Park; Koyar Afrasyab; Petr Y Baranov; Michael J. Young

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 556. doi:

Stem cell therapy enhancement with gold nanoparticles functionalized with nerve growth factor in an animal model of laser damaged retina Open Access

Simona Nicoara; Cristian Berce; Alexandru-Flaviu Tabaran; Cosmina Bouari; Simion Astilean; Monica Potara; Otilia Barbos; Olga Soritau

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 557. doi:

A Complete Retina Patch to Treat Irreversible Retinal Injuries Open Access

Biju Thomas; Bryce T McLelland; Danhong Zhu; Gabriel Nistor; Robert B Aramant; David R Hinton; Mark S. Humayun; Hans S Keirstead; Magdalene J Seiler

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 558. doi:

Adult Mammalian Retinal Regeneration Open Access

Cindy Linn; Megan Stanchfield; Deborah Otteson; Mark Webster

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 559. doi:

Differentiation methods impact the survival and lamination of human pluripotent stem cell-derived retinal organoids Open Access

Carla Bernadette Mellough; Joseph Collin; Rachel Queen; Jannetta S Steyn; Min Yu; Kathryn White; Gerrit Hilgen; David Elliot; Mauro Santibanez-koref; Michael Jackson; Evelyne Sernagor; Majlinda Lako

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 560. doi:

Laminin γ3 expression and its functional role during human retinal morphogenesis Open Access

Birthe Dorgau; Alex Sharpe; Majed Felemban; Dean Hallam; David Steel; Susan Lindsay; Carla Bernadette Mellough; Majlinda Lako

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 561. doi:

DHA promotes differentiation of photoreceptor cells in 3D neural retinas Open Access

Eisuke Arai; Bhubanananda Sahu; Lindsay Perusek; Vipul Parmar; Akira Murakami; Akiko Maeda

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 562. doi:

Enhancing Retinal Ganglion Cell Production from Human Pluripotent Stem Cell-Derived 3D Retinal Cultures
Open Access

Xiangmei Zhang; Kevin Nguyen; Steven A Barnes; Xian-Jie Yang

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 564. doi:

Using statistical models to identify key variables critical for generation of retinal organoids from iPSC Open Access

Valeria Chichagova; Dean Hallam; Mike Nicholds; Robert Thomas; Majlinda Lako; Lyle Armstrong

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 565. doi:

Optimization of xeno-free 3D culture method for retinal differentiation from pluripotent cells
Open Access

Tatiana Perepelkina; Petr Y Baranov

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 566. doi:

Development of a 3-dimensional microphysiological Retina-on-a-chip system Open Access

Jasmin Haderspeck; Kevin Achberger; Christopher Probst; Julia Rogal; Johanna Chuchuy; Wadood Haq; Peter Loskill; Stefan Liebau

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 567. doi:

Investigation of Retinal Ganglion Cell Diversity and Subtype Specification from Human Pluripotent Stem Cells Open Access

Jason S Meyer; Sarah Ohlemacher; Clarisse Fligor; M Joseph Phillips; Peng Jiang; David M Gamm; Kirstin Langer

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 568. doi:

The CRX allelic deletion in ES cells rendering delayed maturation of photoreceptors in three-dimensional Retinal organoids differentiation Open Access

Deng Pan; Xi-Xi Xia; Hui Liu; Shao-Hui Pan; Mei-Ling Gao; Zi-Bing Jin

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 569. doi:

Using hESC-derived retinal organoids to investigate the transcriptional profile of emerging photoreceptors Open Access

Joseph Collin; Rachel Queen; Carla Bernadette Mellough; Majlinda Lako

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 570. doi:

COMPASS acts as a temporal rheostat to control retinal neuroectoderm versus mesoderm fate choice. Open Access

Rajesh C Rao; Qiang Li; Fengbao Mao; Yali Dou

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 571. doi:

Differentiation of human iPSC-derived optic vesicles into numerous types of retinal cells Open Access

Kana Orihara; Chiho Yabuta; Mitsuyoshi Azuma; Noriyuki Azuma

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 572. doi:

CRISPR/Cas9 Edited hiPSCs to Model Neural Retina Differentiation Open Access

Phuong Lam; Christian Gutierrez; Katia Del Rio-Tsonis; Michael L. Robinson

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 573. doi:

Transcriptomic analysis of retinal organoids from human pluripotent stem cells Open Access

Melissa Kaye Jones; Anna R Ogata; Fei Su; Bolin Chen; Justin Seid; Karl Wahlin

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 574. doi:

Three-dimensional retinal organoids from induced pluripotent stem cells derived from rd16 mouse model of CEP290-LCA Open Access

Holly Chen; Koray Dogan Kaya; Coco Ke Jiang; Anupam Mondal; Matthew Brooks; Jung-woong Kim; Manju Swaroop; Wei Zheng; Anand Swaroop

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 575. doi:

The role of brain-derived neurotrophic factor on retinal dysfunction in diabetic retinopathy and its association with eicosapentaenoic acid. Open Access

Rina Namba; Hiroki Kaneko; Keiko Kataoka; Taichi Tsunekawa; Toshiyuki Matsuura; Ayana Suzumura; Hideyuki Shimizu; Hiroko Terasaki

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 576. doi:

The lizard third eye Open Access

Katie Irwin; Ashley Margret Rasys; Tathiana Roldan; Douglas B Menke; James D Lauderdale

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 577. doi:

Vwc2l affects eye development and interacts with olfm1 in zebrafish Vwc2l affects eye development and interacts with olfm1 in zebrafish Open Access

Naoki Nakaya; Mohor Biplab Sengupta; Stanislav I Tomarev

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 578. doi:

Microglial development in the eye and brain
Open Access

Ryo Mukai; Yoko Okunuki; Clifford Kim; Dong Ho Park; Deeba Husain; Kip M Connor

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 580. doi:

Conditional deletion of VEGFR-1 in smooth muscle cells causes decreased retinal vessel growth and reduced alveolarisation in mice Open Access

Xiangke Yin; Yuxiang Du; Zhimin Ye; Qishan Chen; Lijuan Huang; Liu Lixian; Xuri Li; Rong Ju

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 581. doi:

Six3 and Six6 are required for protecting multipotent retinal progenitors against ciliary margin fate through suppressing Wnt/β-catenin signaling Open Access

Wei Liu; Raven Diacou; Ales Cvekl

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 582. doi:

Expression of an opsin protein in developing starburst amacrine cells. Open Access

Sumathi Sekaran; Philip Moseley; Sarah Regan; Christie K Campla; Suzanne Broadgate; Anand Swaroop; Stephanie Halford

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 583. doi:

Transgenic trβ2 expression does not induce full red cone morphology despite inducing red cone physiology Open Access

Leah Middleton; Ralph F Nelson

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 584. doi:

Enhancement of mitotic activity in the chick retina following optic nerve section and growth factor treatment Open Access

Vivian Choh; Stacey A Chong; Anita Kumar; Natalie Hutchings; Christine Frances Wildsoet

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 585. doi:

Laminin β2 Chain Regulates Retinal Progenitor Cell Mitotic Spindle Orientation Via Dystroglycan Open Access

William J Brunken; Dmitri Serjanov; Galina Bachay; Dale D Hunter

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 586. doi:

Mouse retinal development at single-cell resolution Open Access

Brian S Clark; Genevieve Stein-O'Brien; Fatemeh Rajaii; Gabrielle H Cannon; Fion Shiau; Erik Aranda-Michel; Elana J Fertig; Loyal A Goff; Seth Blackshaw

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 587. doi:

Candidate gene analysis at two QTL modulating AII amacrine cell number in mouse retina Open Access

Bridget Kulesh; Patrick William Keeley; Benjamin E Reese

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 588. doi:

Anolis sagrei lizard—a novel model system for studying fovea development Open Access

Ashley Margret Rasys; Katie Irwin; Sherry Luo; Douglas B Menke; James D Lauderdale

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 589. doi:

Gbx2 regulates the development of a non-GABAergic non-Glycinergic amacrine cell in the mammalian retina. Open Access

Patrick C Kerstein; Joseph Leffler; Benjamin Sivyer; William Rowland Taylor; Kevin Wright

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 590. doi:

Pivotal roles of Fezf2 in differentiation of cone OFF bipolar cells and functional maturation of cone ON bipolar cells in developing mouse retina Open Access

Sumiko Watanabe; Atsushi Mizota; Haruna Suzuki

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 591. doi:

Eye Development in the Brown Anole Lizard Anolis sagrei Open Access

James D. Lauderdale; Ashley Margret Rasys; Shana HW Pau; Katie Irwin; Sherry Luo; Douglas B Menke

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 593. doi:

Expression of developmental commitment factors in the regenerating adult zebrafish retina
Open Access

Manuela Lahne; Margaret Brecker; Sarah Semanek; David R Hyde

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 594. doi:

QTLs on Chromosomes 3 and 13 interact to modulate horizontal cell number in the mouse retina Open Access

Patrick William Keeley; Benjamin E Reese

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 595. doi:

Growth coordination of mouse eye compartments by NF2-Hippo-Yap/Taz signaling cascade Open Access

Jin Woo Kim; Kyeong Hwan Moon

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 596. doi:

Roles of NAD for the survival of retinal progenitors through the regulation of pro-apoptotic gene expression via Sirt-mediated histone acetylation Open Access

Akira Murakami; Hiroshi Kuribayashi; Yukihiro Baba; Eisuke Arai; Sumiko Watanabe

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 597. doi:

in vitro photoprotective effect of optical filters on retinal pigment epithelium cells exposed to moderate daylight-mimicking conditions Open Access

Melanie MARIE; Coralie Barrau; Camille EHRISMANN; Pauline GONDOUIN; Jose A. Sahel; Thierry Villette; Serge A Picaud

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 598. doi:

Assessing rod function in cone dystrophy patients with ABCA4 mutations using rod fractional sensitivity estimates based on ERG a-wave rise time Open Access

Kristen E Bowles Johnson; Brett Jeffrey; Laura J Frishman

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 599. doi:

A computational method for determining opsin peak absorbance wavelengths from zebrafish PIII ERG responses Open Access

Ralph F Nelson; Annika Balraj; Tara Suresh; Meaghan Torvund; Sara Stokes Patterson

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 600. doi:

Effect of Forskolin on Recovery of the Cone Photoresponse in Grk Knockout Zebrafish Larvae Open Access

Jared David Chrispell; Shoji Osawa; Ellen R Weiss

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 601. doi:

Deletion of an Nrl-regulated alternative promoter results in retina-specific silencing of Frmpd1, a gene involved in mediating rod adaptation Open Access

Christie K Campla; Stephanie Halford; Sumathi Sekaran; Lijin Dong; Anand Swaroop

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 602. doi:

Chemogenetic manipulation of feedback inhibition from horizontal cells to photoreceptors in transgenic zebrafish expressing alien neurotransmitter receptors Open Access

Billie Beckwith-Cohen; Lars Holzhausen; Richard H Kramer

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 603. doi:

Pointillism in the retina: a new method to semi-automaticly assess rods and cones density in immunostained retinas. Open Access

Anna Verschueren; valerie fradot; Serge A Picaud; José Alain SAHEL

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 604. doi:

Identification of protein components of the rod outer segment plasma membrane by label-free protein correlation profiling Open Access

Nikolai P Skiba; Laurie Molday; Robert S Molday; Vadim Y Arshavsky

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 605. doi:

Light-induced length shrinkage of photoreceptor outer segment Open Access

Yiming Lu; Jacopo Benedetti; Xincheng Yao

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 606. doi:

Horizontal Cell Specific Dopamine Receptor Knock Out Causes ON vs OFF-pathway Specific Dysfunction in Spatial Tuning and Light Adaptation in the Retina Open Access

David Sprinzen; Douglas McMahon

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 607. doi:

Relationship between Ocular Versions and Superior Oblique Muscle Hypoplasia in Unilateral Superior Oblique Palsy Open Access

Jeong-Min Hwang; Ji Eun Lee; Hee Kyung Yang

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 608. doi:

Dynamics of ocular myasthenia gravis, generalized myasthenia gravis and remission: a retrospective cohort study in southern Thailand Open Access

Juthamat Witthayaweerasak; Nipat Aiu-aree

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 609. doi:

Retinal Sensitivity Reduced in Patients with Multiple Sclerosis and Neuromyelitis Optica Spectrum Disorder with no History of Optic Neuritis Open Access

Hirotaka Yokouchi; Takayuki Baba; Shuichi Yamamoto

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 610. doi:

Diagnostic Value of Fatigue-Induced Ice Test in the Evaluation of Ptosis in Myasthenia Gravis Open Access

Hyun Ju Kee; Hee Kyung Yang; Jeong-Min Hwang; Kyung Seok Park

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 611. doi:

Hand-held Optical Coherence Tomography – A New Biomarker of Brain Swelling in Cerebral Malaria Open Access

Zhanhan Tu; Viral Sheth; Jack Gormley; Chatonda Manda; Frank A Proudlock; Karl Seydel; Terrie Taylor; Simon P Harding; Irene Gottlob

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 612. doi:

Retinal neuronal loss detected by swept-source optical coherence tomography in patients with mild cognitive impairment Open Access

Leonardo Provetti Cunha; Ana Laura Maciel Almeida; Luciana Virgínia Ferreira Costa-Cunha; Evelyn Alvernaz Figueiredo; Rony Carlos Preti; Leandro C Zacharias; Mario L R Monteiro

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 613. doi:

Validation of an equation model to predict intracranial pressure in clinical studies Open Access

Niro Kasahara; Mateus Matuoka; Katia Santos; Natasha Cruz; Alvaro R Martins; Stanley Nigro

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 614. doi:

Anterograde microstructural changes along the visual pathways in optic neuritis Open Access

Yuyi You; Chenyu Wang; Sidong Liu; Stuart L Graham; Alexander Klistorner

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 615. doi:

Diagnostic Yield of Laboratory Testing and Imaging Studies in Patients with Optic Atrophy in an Inner City Population Open Access

Rebecca Moran; Nancy Blace; Nour Haddad; Tybee Eleff

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 616. doi:

Retinal Nerve Fiber Layer Thickness in Migraine and its Correlation to Duration and Severity of Disease Open Access

Dianne A Barrett; Nafiseh Hashemi; Ore-Ofe O Adesina

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 617. doi:

Retinal hypoperfusion in patients with Alzheimer’s disease Open Access

Yi Liu; Hong Jiang; Yuqing Deng; Zhengyu Duan; Tatjana Rundek; Xiaoyan Sun; Bernard S. Baumel; Jonathan Landman; Jianhua Wang

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 618. doi:

The Impact of Optic Nerve Disorders on Sleep Wake Open Access

Sarah Ruth Stevenson; Colm Andrews; Iona Alexander; Marcela Votruba; Patrick Yu-Wai-Man; Susan Downes; Russell Foster

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 619. doi:

Early Visual Biomarkers in a Mouse Model of Multiple Sclerosis Open Access

Oliver W Gramlich; Kasra Zarei; Alexander J Brown; Randy H Kardon

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 620. doi:

Pupillary response dynamics of mydriasis measured with multifocal pupillography. Open Access

Bhim Bahadur Rai; Faran Sabeti; Corinne F Carle; Ozge Sarac; Emilie Rohan; Ted Maddess

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 621. doi:

The population-based epidemiology of ocular diseases in multiple sclerosis
Open Access

Sarah Chao Ying Xu; Eoin Flanagan; Feng Wang; Jacqueline Leavitt; John J Chen

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 622. doi:

Axonal protection by a small molecule SIRT1 activator, SRT2104, with alteration of autophagy in optic nerve degeneration
Open Access

Yasushi Kitaoka; Kana Sase; Chihiro Tsukahara; Hitoshi Takagi

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 623. doi:

Akebia Saponin D prevents axonal loss against TNF-induced optic nerve damage with autophagy modulation
Open Access

Kana Sase; Yasushi Kitaoka; Chihiro Tsukahara; Hitoshi Takagi

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 624. doi:

Validation of microsaccades as a biomarker for disability in multiple sclerosis Open Access

Christy K Sheehy; Bingyan Shi; Ethan Bensinger; Andrew Romeo; Lakshmisahithi Rani; michael devereux; Jeffrey Gelfand; Scott B Stevenson; Ari Green

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 625. doi:

Axonal protection by tacrolimus with inhibition of NFATc1 in TNF-induced optic nerve degeneration Open Access

Chihiro Tsukahara; Yasushi Kitaoka; Kana Sase; Hitoshi Takagi

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 626. doi:

Monozygotic Twin Correlations of Retinal and Cerebral Vascular Parameters Open Access

Aleid van de Kreeke; Ton Nguyen; Elles Konijnenberg; Anouk Den Braber; Mara ten Kate; Pieter Jelle Visser; Frank D Verbraak

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 627. doi:

Optimization of visual performance in patients with age-related macular degeneration using biofeedback training Open Access

Mirella Telles Salgueiro Barboni; Zsuzsa Récsán; Zsuzsanna Szepessy; Mónika Ecsedy; Kornél Szekeres; Miklós Maczkó; Agnes Urbin; Balazs Vince Nagy; Dora F. Ventura; Janos Nemeth

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 628. doi:

Comparative Effectiveness of a Self-Guided Eye Movement Reading Training Program: Clinic vs. Home Open Access

Meesa Maeng; William H Seiple; Charlotte Jackson; Kaitlyn Randolph; Janet P Szlyk

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 629. doi:

Training to improve speed of letter recognition benefits reading speed in people with central vision loss Open Access

Susana T L Chung

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 630. doi:

Critical spacing of contour interaction for children with Cerebral Visual Impairment (CVI) Open Access

Jasmine Junge; Deborah A Orel-Bixler

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 631. doi:

Eyedaptic Augmented Reality Visual Aid Leads to Improved Reading Speed and Accuracy in Individuals with AMD Open Access

Mitul C Mehta; Brian T Kim; REBECCA KAMMER; Dave Watola

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 633. doi:

Comparison of Head Borne Electronic Low Vision Devices in Patients with Visual Impairment Open Access

Erica Joy Troyer; Margaret Dixon

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 634. doi:

Gaze-contingent screen magnification control Open Access

Roberto Manduchi; Susana T L Chung

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 635. doi:

Clinical use of a novel retinal imaging laser eyewear Open Access

Takahiro Minami; Yukako Taketani; Manabu Nakamura; Yusuke Yasuda; Satoshi Kato

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 636. doi:

Measuring the usefulness of strabismic field expansion in hemianopia Open Access

Philip M. Bronstad

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 637. doi:

High power multi-periscopic device for field expansion Open Access

Eli Peli; Jae-Hyun Jung; Nish Mohith Kurukuti; Fernando Vargas Martin

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 638. doi:

No useful field expansion for hemianopia or acquire monocular vision with full-field prisms Open Access

Jae-Hyun Jung; Eli Peli

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 639. doi:

Head Mounted Display Technology for Low Vision due to Peripheral Field Loss Open Access

Yooree Chung; Andrew Chen; Shirin E Hassan; Manuel Soto Santiago; Lauro Ojeda; David C Musch; Donna Wicker; Sherry Day; Ashley Howson; James D. Weiland; Sayoko Eileen Moroi; Joshua R Ehrlich

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 640. doi:

Feasibility of using Bluetooth Beacon Sensors to Monitor Usage of Hand-held Low Vision Devices at Home Open Access

Ava K Bittner; Rakin Khan

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 641. doi:

Preliminary evaluation of Bluetooth beacons on hand-held magnifiers as sensors to detect usage via increased temperature when held by low vision patients in clinic Open Access

Rakin Khan; Katherine Green; Ava K Bittner

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 642. doi:

Smartphone and tablet usage among individuals with vision impairment: Are mainstream devices replacing traditional visual aids? Open Access

Natalie Martiniello; Magdalena Bittner; Werner Eisenbarth; Christine Lehane; Aaron Johnson; Walter Wittich

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 643. doi:

Near Infrared Adaptive Optics Flood illumination ophthalmoscope Angiography Open Access

Elena Gofas Salas; Pedro Mecê; Cyril Petit; Kate Grieve; Laurent Mugnier; Jose A. Sahel; Michel Paques; Serge Meimon

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 644. doi:

Long-term stability and repeatability of the late phase adaptive optics enhanced indocyanine green signal demonstrates potential clinical utility for evaluation of the retinal pigment epi... Open Access

Johnny Tam; HaeWon Jung; Tao Liu; Michael Droettboom; Laryssa Huryn; Jianfei Liu

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 645. doi:

Analysis of periarteral capillary free zone in optical coherence tomography angiography of normal retina and its’ association with severe nonproliferative diabetic retinopathy
Open Access

JIN MA; honghui li; Xiaohu Ding; Lin Lu

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 646. doi:

Measuring local flicker evoked changes in retinal capillary blood flow using a dual-beam Adaptive Optics Scanning Laser Ophthalmoscope Open Access

Raymond Luval Warner; Alberto De Castro; Ting Luo; Kaitlyn Sapoznik; Lucie Sawides; Stephen A Burns

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 647. doi:

Survey of transient hyporeflective clusters of cones in healthy eyes Open Access

Ethan bensinger; Yiyi Wang; Sowmya Ravikumar; Brian Patrick Schmidt; Austin Roorda

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 648. doi:

Foveal and parafoveal between-individual variation in in-vivo cone-to-RPE cell ratio Open Access

Rigmor C Baraas; Hilde Rogeberg Pedersen; Stuart J. Gilson

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 649. doi:

Optophysiological function of individual cones
Open Access

Robert F Cooper; William Scott Tuten; David H Brainard; Jessica Ijams Wolfing Morgan

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 650. doi:

In Vivo Measurements of Cone Photoreceptor Parameters in Eyes with Different Vision from Images Obtained by an Adaptive Optics Retinal Camera
Open Access

Yuanbo Liang; Huanhuan Cheng; Sigen Lin; Kenneth J Ciuffreda; Balamurali Vasudevan; Kun Zhou

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 651. doi:

Comparing metrics for quantifying the human rod photoreceptor mosaic Open Access

Emily J Patterson; Christopher S Langlo; Robert F Cooper; Joseph Carroll

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 652. doi:

Plucking strings and playing chords: percepts elicited from single and multiple cone stimulation Open Access

Brian Patrick Schmidt; Alexandra E Boehm; Austin Roorda

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 653. doi:

Visual benefit of correcting High Order Aberrations in blue or green light: an optical effect? Open Access

Susana Marcos; Clara Benedi; Maria Vinas; Carlos Dorronsoro; Stephen A Burns; Eli Peli

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 654. doi:

Longitudinal Chromatic Aberration(LCA) compensation for adaptive optics vision testing and imaging Open Access

Xiaoyun Jiang; James Kuchenbecker; Zhaojie Yao; Ramkumar Sabesan

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 655. doi:

The role of fixational eye movements in maintaining a stable fixation locus Open Access

Kavitha Ratnam; Norick R Bowers; Austin Roorda

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 656. doi:

Toward Automated Alignment of Longitudinally-Acquired Adaptive Optics Retinal Images: Constellation Features Open Access

Min Chen; Robert F Cooper; Grace K. Han; James Gee; David H Brainard; Jessica Ijams Wolfing Morgan

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 658. doi:

Dynamic Pupil Tracking for Adaptive Optics Visual Simulator with Liquid Crystal Spatial Light Modulator Open Access

Fan Yi; Brett A Davis; Hamish McNeill; Michael J Collins

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 659. doi:

Improvements to manual registration of AOSLO image sequences Open Access

Dirk-Uwe G Bartsch; Manuel Amador; Amit Meshi; Kunny C Dans; Tiezhu Lin; William R Freeman

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 660. doi:

Dual Scan AOSLO Imaging for measuring eye velocity and correcting eye motion distortion of images. Open Access

Stephen A Burns; Ting Luo

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 661. doi:

Exploring directional retinal light scattering using a digital micromirror device
Open Access

Salihah Qaysi; Brian Vohnsen

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 662. doi:

High speed, spectral domain, line field OCT Open Access

VIMAL PRABHU PANDIYAN; Aiden Maloney Bertelli; Ramkumar Sabesan

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 663. doi:

Evaluation of a combined ultra-wide field SLO with SD OCT Open Access

Nathan Joseph Gresores; Michael Singer; Anne Marie Cairns; Michael J Sinai; Srinivas R. Sadda

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 664. doi:

The interference pattern of the anterior surface of the human eye: an Optical Coherence Tomography Study Open Access

CLAUDIO IOVINO; Maurizio Fossarello; Mirco Braghiroli; Pietro Emanuele Napoli

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 665. doi:

RPE disruption with long duration visible light exposure is governed by a photochemical damage mechanism Open Access

Jie Zhang; David R Williams; Jennifer J Hunter

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 666. doi:

Retinal structure variation in congenital aniridia: within family phenotype-genotype discordance Open Access

Hilde Rogeberg Pedersen; Maureen Neitz; Stuart J. Gilson; Erlend Christoffer Sommer Landsend; Øygunn Aass Utheim; Tor Paaske Utheim; Rigmor C Baraas

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 667. doi:

Repeatability of Flood-Illuminated Adaptive Optics Imaging in Subjects with Retinitis Pigmentosa Open Access

Michael Gale; Gareth Harman; Jimmy Chen; Mark E Pennesi

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 668. doi:

Characterization of retinal structure in ATF6-associated achromatopsia Open Access

Rebecca Mastey; Michalis Georgiou; Christopher S Langlo; Angelos Kalitzeos; Ajoy Vincent; Anthony T Moore; Stephen H. Tsang; Jonathan H Lin; Marielle Young; M Elizabeth Hartnett; Elise Heon; Susanne Kohl; Michel Michaelides; Joseph Carroll

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 669. doi:

Quantification of retinal traction caused by epiretinal membrane (ERM) using en face optical coherence tomography and its influence on visual function. Open Access

Yuki Kanzaki; Yuki Morizane; Masayuki Hirano; Shuhei Kimura; Mio Hosokawa; Yusuke Shiode; Shinichiro Doi; Shinji Toshima; Kosuke Takahashi; Atsushi Fujiwara; Mika Hosogi; Fumio Shiraga; Ippei Takasu

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 670. doi:

Assessment of lamellar macular hole and macular pseudohole with a combination of en face and radial B-scan optical coherence tomography imaging Open Access

Hirano Masayuki; Yuki Morizane; Shuhei Kimura; Mio Hosokawa; Yusuke Shiode; Shinichiro Doi; Shinji Toshima; Kosuke Takahashi; Mika Hosogi; Atsushi Fujiwara; Ippei Takasu; Fumio Shiraga

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 671. doi:

Physiologic origin of intrinsic optical signals in human retina Open Access

Clara Pfäffle; Dierck Hillmann; Hendrik Spahr; Lisa Kutzner; Bastian Kabuth; Sazan Burhan; Felix Hilge; Gereon Hüttmann

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 672. doi:

Evaluation of optical coherence tomography volumetric data prior to analysis Open Access

Homayoun Bagherinia; Ali Fard; Mary K Durbin

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 673. doi:

Trend in Utilizing Wide-Field Fundus Photography in Ophthalmology Open Access

Laura C. Huang; Diana V Do

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 675. doi:

Correlation between bright light and lens-induced myopia Open Access

Cindy Karouta; Kate Thomson; Regan Scott Ashby

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 676. doi:

Violet light exposure suppresses refractive change and axial elongation in a murine model of lens-induced myopia Open Access

Toshihide Kurihara; Xiaoyan Jiang; Kiwako Mori; Shin-cihi Ikeda; Hidemasa Torii; Kazuo Tsubota

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 677. doi:

Influence of chromatic light on lens-induced myopia in mice Open Access

Ryan Strickland; Erica Landis; Machelle T Pardue

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 678. doi:

Short-wavelength cone contrast reverses the sign of defocus for emmetropization in chick Open Access

Frances J Rucker; Christopher Patrick Taylor

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 679. doi:

The Relation of Light Spectral Composition and Dopamine D1 and D2 Receptors in Lens Induced Myopia in Guinea Pigs Open Access

Wangyuan Liu; Jinhui Dai

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 681. doi:

Effects of 0.5Hz and 20Hz Flash 530nm Monochromatic Illumination on Refraction Development in Guinea Pigs Open Access

Tian Tian; Hong Liu; Rui Liu

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 682. doi:

Indoor Illuminants, S-Cone Stimulation, and Eye Growth in Chicks Open Access

Hannah H Yoon; Christopher Patrick Taylor; Frances J Rucker

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 683. doi:

Effects of different light exposure paradigms before myopia is induced Open Access

Marita P Feldkaemper; Sandra Bernhard-Kurz; Frank Schaeffel

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 684. doi:

Combined effects of bright light and intravitreal atropine on retinal dopamine release in chickens Open Access

Ute Mathis; Marita P Feldkaemper; Min Wang; Frank Schaeffel

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 685. doi:

Effects of spectral composition of light on dopamine release and myopia development in chicks Open Access

Min Wang; Frank Schaeffel; Marita P Feldkaemper

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 686. doi:

The effect of blue light on the guinea pigs with lens induced myopia Open Access

manrong yu; Jinhui Dai

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 687. doi:

Effects of Quasi-Monochromatic Long-wavelength Ambient Lighting on Form-Deprivation Myopia in Infant Rhesus Monkeys Open Access

Li-Fang Hung; Baskar Arumugam; Zhihui She; Earl L Smith

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 688. doi:

Effects of Caffeine, an Adenosine Receptor Antagonist, on Lens Compensation in Rhesus Monkeys Open Access

Zhihui She; Baskar Arumugam; Li-Fang Hung; Monica Jong; Lisa A Ostrin; Earl L Smith

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 689. doi:

Intravitreal injection, but not topical instillation, of atropine inhibits myopic shift in the chick lens-induced myopia model Open Access

Takaaki Inaba; Tomoko Oda; Toru Shibata; Hitomi Kamio; Kenji Ueda; Masatomo Kato; Jin-Zhong Zhang

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 690. doi:

Topical Atropine Prevents Contact Lens-Induced Myopia in Guinea Pigs Open Access

Sarah Kochik; Christine Frances Wildsoet

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 691. doi:

Low dose Atropine for Myopia Progression (LAMP) Study: A Double-blinded Randomized Placebo-Controlled Trial on atropine 0.05%, 0.025%, and 0.01% Open Access

Jason YAM; Yuning Jiang; Shu Min Tang; Antony Law

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 692. doi:

Atropine applied at different times of day has different effects on choroid thickness Open Access

Pauline Kang; Stefanie Clendaniel; Anne Li; Cindy Van; Xiaoying Zhu; David Troilo; Alexandra Benavente-Perez

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 693. doi:

M to L cone ratios determine eye size in chicks Open Access

Sandra Gisbert Martinez; Frank Schaeffel

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 694. doi:

Quantification and distribution of co-localized astrocytes and capillaries in the inner retina of juvenile marmosets, normative data for myopia studies Open Access

Carol Lin; NEFELI SLAVI; Ana Nour; Miduturu Srinivas; Amy Pope; Victor Lin; Rita Nieu; Alexandra Benavente-Perez

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 695. doi:

Retinal ON-pathway responses in marmosets experiencing positive lens defocus Open Access

Rita Nieu; Alexandra Benavente-Perez; Ana Nour; Amy Pope; Carol Lin; Victor Lin; Suresh Viswanathan

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 696. doi:

Measuring changes in fundal reflectance in myopic chickens with isotropic photorefraction. Open Access

Barbara Swiatczak; Marita P Feldkaemper; Frank Schaeffel

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 697. doi:

Gene expression profiling in the retina of Collaborative Cross mice reveals pathways underlying refractive eye development and susceptibility to myopia Open Access

Tatiana V Tkatchenko; Andrei V Tkatchenko

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 698. doi:

Relative protein quantification in lens-induced chick retina by iTRAQ-based proteomics approach Open Access

Hui Zheng; Ka Wai, Jimmy CHEUNG; King Kit Li; Xin Tang; Chi Ho To; Dennis Tse; Thomas Chuen Lam

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 699. doi:

Risk variances of refractive error and axial length explained by polygenic risk scores of spherical equivalents Open Access

Clair Enthoven; Adriana I Iglesias; Milly S. Tedja; Willem Tideman; Jan Roelof Polling; Virginie JM Verhoeven; Caroline C W Klaver

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 700. doi:

Whole-Genome Sequencing Identifies UTR Variants in LRPAP1 in a Large Iranian Family with High Myopia Open Access

Terri L Young; Kristina Whisenhunt; Stuart Tompson; Reza Maroofian; Maryam Najafi; Abolfazl Rad

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 701. doi:

Family-Based Association Tests of Myopia reveal a potentially hidden association signal upstream of two GABA receptor genes Open Access

Candace Middlebrooks; Claire L. Simpson; Anthony Musolf; Laura Portas; Federico Murgia; Elise B. Ciner; Dwight Stambolian; Joan E Bailey-Wilson

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 702. doi:

Dopaminergic and serotoninergic signaling in black fur BL6 and albino, rag2-/-, immunodeficient BL6 mice subjected to lens-induced (LIM) and form-deprivation myopia (FDM) Open Access

Qianwen Gong; Longqian Liu; Miroslaw Janowski

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 704. doi:

Cone photoreceptors and optical signals to defocus following emmetropization to lenses in chicks Open Access

Mengyuan Ke; Elizabeth L Irving; Marsha Kisilak; Melanie C W Campbell

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 705. doi:

Optical defocus changes signaling of ganglion cells in the mouse retina Open Access

Feng Pan; Seema Banerjee; Ka Shing LUK; Chi Keung TANG; Siu Fan YU

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 706. doi:

Differential BMP Gene Expression Persists in Chick RPE Following Termination of Retinal Defocus and Image Degradation Treatments Open Access

Christine Frances Wildsoet; Daniel Sun; Grace May Chuang; Yan Zhang

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 707. doi:

Scleral Crosslinking Using Genipin Has a Dose-Dependent Effect on Form-Deprivation Myopia in Tree Shrews Open Access

Rafael Grytz; Mustapha El Hamdaoui; Alexander Miles Levy; Christopher A Girkin; Brian C Samuels

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 708. doi:

Substantial Preconditioning Effect Observed In the Inflation Tests of Juvenile Tree Shrew Sclera Open Access

Gianfranco Bianco; Alexander Miles Levy; Rafael Grytz; Massimo Antonio Fazio

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 709. doi:

Identification of Specific Binding Sites for Apolipoprotein A-1/Retinoic acid Complexes on Scleral Cell Membranes Open Access

Jody A Summers

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 711. doi:

An ultrasound-based biomarker of myopia in the guinea pig sclera Open Access

Jonathan Mamou; Sally A McFadden; Quan V Hoang

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 712. doi:

scleral crosslinking using glyceraldehyde for the prevention of myopia progression in the rabbit: biochemical and ultrastructural changes Open Access

Xiao Lin; Hao Zhou

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 713. doi:

Efficacy of Rose Bengal as a Light Activated Cross-Linker in Guinea Pig Sclera Open Access

Sally A McFadden; Nikki Cox; Yusuf Abdulla

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 714. doi:

Stiffening of rabbit sclera by bacteriochlorophyll derivative WST11 and near infrared illumination (NIR)through the cornea Open Access

Alexandra Goz; Jurriaan Brekelmans; Arie Marcovich; Alexander Brandis; XiaoMeng Sui; Daniel Wagner; Sidney Cohen; Avigdor Scherz

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 715. doi:

Experimental malarial retinopathy reveals vascular alterations, parasite neuroretina infiltration, and neuronal cell death Open Access

Francois Paquet-Durand; Susanne Beck; Soumyaparna Das; Timm Schubert; Naoyuki Tanimoto; Marina Garcia-Garrido; Regine Muehlfriedel; Sylvia Bolz; Benjamin Mordmueller; Mathias W Seeliger

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 716. doi:

The Use of Predatory Prokaryotes to Control an Ocular Pathogen in the Vitreous Open Access

Eric G Romanowski; Kimberly Brothers; Daniel E Kadouri; Robert M Q Shanks

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 717. doi:

Murine cytomegalovirus (MCMV) disseminates to and remains latent in the choroid following systemic infection of neonatal BALB/c mice
Open Access

Ming Zhang; Jinxian Xu; Xinglou Liu; Brendan Marshall; Zheng Dong

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 718. doi:

Ebola Virus Persistence in Ocular Tissues and Fluids (EVICT) Study: Ebolavirus RT-PCR Results and Cataract Surgery Outcomes Open Access

Jessica Shantha; John Mattia; Augustine Goba; Ian Crozier; Kayla Barnes; Brent Hayek; Colleen Kraft; Jessica Hartnett; Nisha Acharya; Moges Teshome; Paul Farmer; Lowell Gess; robert Garry; Matthew Jusu Vandy; Steven Yeh

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 719. doi:

An aberrant immune response to an ocular commensal results in disease in a mouse model of Muckle-Wells Syndrome Open Access

Kumarkrishna Raychaudhuri; Anthony St. Leger; Fatimah Almaghrabi; Ivan J Fuss; Warren Strober; Rachel R Caspi

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 720. doi:

Retinal microcirculation, microvasculature and microstructure in patients with multiple sclerosis: 1 year follow-up Open Access

Hong Jiang; Ce Shi; Zhengyu Duan; Silvia Delgado; Giovanni Gregori; Jeffrey Hernandez; Jianhua Wang

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 721. doi:

Anterior and posterior ocular structures change during long-duration spaceflight and one year after landing Open Access

Brandon Macias; Nimesh B Patel; Charles R Gibson; Brian C Samuels; Stuart Lee; Robert Ploutz-Snyder; Ashot Sargsyan; David Alexander; Roy Riascos; Larry Kramer; Steven Laurie; Thomas Mader; Tyson Brunstetter; Christian Otto; Michael B Stenger

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 722. doi:

A new approach for diagnosing internuclear ophthalmoplegia with infrared oculography Open Access

Jenny Nij Bijvank; Lisanne Balk; Stevie Tan; Bernard Uitdehaag; Axel Petzold; René van Rijn

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 723. doi:

Optical Coherence Tomography Angiography in amyloid proven Alzheimer’s disease; a non-invasive biomarker? Open Access

Jurre den Haan; Aleid van de Kreeke; Johannes de Boer; Femke Bouwman; Frank D Verbraak

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 724. doi:

Retinal venule diameters decreased following 6 months of treatment for high intracranial pressure in Idiopathic Intracranial Hypertension Treatment Trial participants Open Access

Heather E Moss; Rachel A Hollar; William S Fischer; Steven E Feldon

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 725. doi:

Effect of stimulus intensity, visual field location and duration on the rod- , cone- and melanopsin- mediated pupillary light reflex Open Access

Ifat Sher-Rosenthal; Soad Haj Yahia; Amit Hamburg; Yisroel Tucker; Daniel Ben Ner; Saeed Yassin; Ron Chibel; Estela Derazne; Ygal Rotenstreich

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 726. doi:

Sustained and transient pupil responses in the mesopic range Open Access

John L Barbur

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 727. doi:

Imaging retinal function with phase-sensitive adaptive optics optical coherence tomography Open Access

Kazuhiro Kurokawa; James A. Crowell; Furu Zhang; Zhuolin Liu; Donald Thomas Miller

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 728. doi:

Histologic correlation of cone photoreceptor maturation with ultrahigh resolution OCT in wild type swine Open Access

Niloofar Piri; Patrick A Scott; Henry J Kaplan; Bhubanananda Sahu; Maureen A McCall

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 729. doi:

Influence of light on the diurnal rhythm of photoreceptor disc shedding in humans Open Access

Furu Zhang; Kazuhiro Kurokawa; Ayoub Lassoued; James Alan Crowell; Zhuolin Liu; Donald Thomas Miller

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 730. doi:

The Relationship between Cone Density and Axial Length: CAL Study Open Access

Yiyi Wang; Nicolas Bensaid; Pavan Tiruveedhula; Jianqiang Ma; Austin Roorda; Sowmya Ravikumar

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 731. doi:

Adaptive optics ophthalmoscopy in the awake, behaving mouse Open Access

Jesse B. Schallek; Aby Joseph; Qiang Yang; Krishnan Padmanabhan; Charles Pfeifer

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 732. doi:

High speed high resolution anamorphic adaptive optics near-confocal ophthalmoscopy Open Access

Xiaolin Wang; Jing Lu; Boyu Gu; Yuhua Zhang

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 733. doi:

Clinically Relevant Outcomes from the DRCR.net Anti-VEGF Treatment Algorithm for Proliferative Diabetic Retinopathy Open Access

Jennifer K Sun

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 735. doi:

Outcomes in proliferative diabetic retinopathy patients who are lost to follow-up after panretinal photocoagulation vs. intravitreal anti-vascular endothelial growth factor injection Open Access

Jason Hsu; Anthony Obeid; Daniel Su; Joshua Uhr; Samir N Patel

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 736. doi:

Automated Hemorrhage and Microaneurysm Counts on Ultrawide Field Images Predict Increased Risk of Diabetic Retinopathy Progression Over 4 Years Open Access

Paolo Sandico Silva; Mohamed Elmasry; Alex Pisig; Yousef Aldairy; jano van hemert; Alan Fleming; Jennifer K Sun; Lloyd P Aiello

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 737. doi:

The development and validation of a deep learning algorithm for referable diabetic retinopathy
Open Access

Stuart Keel; Zhixi Li; Yifan He; Wei Meng; Robert Chang; Mingguang He

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 738. doi:

Quantitative assessment of changes in retinal vascular density and morphology among patients with diabetic retinopathy using spectral domain optical coherence tomography angiography (SD-O... Open Access

Kaitlin Kogachi; TAI-CHI LIN; Neal V Palejwala; Sujit Itty; Jeremy D. Wolfe; Kimberly A Drenser; Antonio Jr. Capone; Pravin U Dugel; Xuejuan Jiang; Anoush Shahidzadeh; Zhongdi Chu; Ruikang K Wang; Amir H Kashani

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 739. doi:

Incorporating Predominantly Peripheral Diabetic Retinopathy (DR) Lesion Identification in a Teleophthalmology Program Predicts DR Progression over 4 Years in Eyes with Early DR Open Access

Mohamed Ashraf Elmasry; Paolo Sandico Silva; jerry Cavallerano; Alex Umali Pisig; Yousef Aldairy; Jennifer K Sun; Lloyd P Aiello

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 740. doi:

Correlation between corneal and retinal neurodegenerative changes and their association to parafoveal microvascular perfusion in patients with type II diabetes Open Access

Julia Hafner; Sonja Karst; Stefan Sacu; Christoph Scholda; Eleonore Pablik; Ursula Schmidt-Erfurth

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 741. doi:

Novel Biomarker for diagnosis, prognosis, and targeted therapy of Keratoconus Open Access

Rabab Sharif; Sashia Bak-Nielsen; Henrik Sejersen; Jesper Hjortdal; Dimitrios Karamichos

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 742. doi:

Homozygous Mutation in the ELMO3 Gene with Keratoconus Open Access

Mariam Lotfy Khaled; Khaled Abu-Amero; Abdulrahman Al-Muammar; Yelena Bykhovskaya; Xiaoyo Gao; Michael A Hauser; R. Rand Allingham; Yaron Rabinowitz; Yutao Liu

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 743. doi:

Increased expression of Retinoic acid-related Orphan Receptor gamma transcription factor and its products in keratoconus patients Open Access

Ruchita Selot; Jagdeesh Naidu; Nimisha Kumar; Rohit Shetty; Rajiv R Mohan; Arkasubhra Ghosh; Swaminathan Sethu

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 744. doi:

Phase-Decorrelation OCT for Noncontact Measurement of Biomechanical Effects of Corneal Crosslinking Open Access

Brecken Blackburn; Shi Gu; Matthew R Ford; Vinicius Silbiger De Stefano; Michael Jenkins; William J Dupps; Andrew Rollins

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 745. doi:

Brillouin ocular analyzer detects biomechanical changes in corneal tissues in the early stages of keratoconus and after corneal crosslinking Open Access

Peng Shao; Amira M Eltony; Theo G Seiler; Behrouz Tavakol; Roberto Pineda II; Theo Seiler; Seok-Hyun (Andy) Yun

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 746. doi:

Native-Like, Cell-Laden, Orthogonal-Multilayer and Transplantable Tissue- Engineered Corneal Stroma Induced by a Mechanical Collagen Microenvironment Open Access

Jiansu Chen; Zekai Cui; Jun Zhang; Qiaolang Zeng; Shiwei Liu; Yonglong Guo; Mengyuan Xie; Jianing Gu; Shibo Tang

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 747. doi:

Sodium hydroxymethylglycinate via eyedrop for corneal cross-linking in Dutch-belted rabbits: a comparison of 40mM (0.5%) vs 80mM (1%) concentrations Open Access

Mariya Zyablitskaya; Daeryl Amponin; Anna Takaoka; Charles Jayyosi; Kristin Myers; Connie Chen; Leejee Suh; Takayuki Nagasaki; Stephen Trokel; David C Paik

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 748. doi:

Dynamic chromatic noise stimulation promotes myopia Open Access

Christopher Patrick Taylor; Frances J Rucker

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 749. doi:

Lens defocus alters dopamine synthesis under different ambient lighting conditions Open Access

Erica Landis; Hannah Lee Park; Li He; Curran Sidhu; Micah A Chrenek; Ryan Strickland; P. Michael Iuvone; Machelle T Pardue

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 750. doi:

Retinal gene expression profiling following exposure to hyperopic or myopic defocus supports retina’s capacity to recognize sign of defocus Open Access

Andrei V Tkatchenko; David Troilo; Alexandra Benavente-Perez; Tatiana V Tkatchenko

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 751. doi:

Retinal Simultaneous Competing Defocus of Opposite Sign Induces Up-Regulation of BMP Gene Expression in Chick RPE Open Access

Yan Zhang; Sara Yasmin Azmoun; John Riches Chhoa; Christine Frances Wildsoet

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 752. doi:

Apomorphine attenuates form deprivation myopia by a dopamine D1 receptor-dependent mechanism in mice Open Access

Xiangtian Zhou; Furong Huang; Lishuai zhang; Qiongsi Wang; Jia Qu

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 753. doi:

Muscarinic-cholinergic and GABA antagonists appear to modulate eye growth independent of the dopaminergic system Open Access

Kate Thomson; Cindy Karouta; Regan Scott Ashby

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 754. doi:

Ocular growth and metabolomics are dependent upon the spectral content of white light Open Access

Raymond Najjar; Juan Manuel Chao De La Barca; Veluchamy A Barathi; Candice Ho Ee Hua; Jing Zhan Lock; Wallace Foulds; Pascal Reynier; Dan Milea

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 755. doi:

Functional properties of human retina measured with Adaptive Optics Open Access

Austin Roorda

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 756. doi:

Optogenetics for vision restoration- translation from mice to non-human primates Open Access

Deniz Dalkara

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 757. doi:

Signaling pathways in the primate retina Open Access

William Rowland Taylor

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 758. doi:

Receptive field diversity in primate lateral geniculate nucleus Open Access

Paul R. Martin

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 759. doi:

Organization and function of feedback connections in early visual processing Open Access

Alessandra Angelucci

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 760. doi:

Modulation of endothelial cell function and pathologic ocular angiogenesis by microRNA-145 Open Access

Chi-Hsiu Liu; Zhongxiao Wang; Ye Sun; Rubi Duran; Alexander Poblete; Steve S Cho; Jing Chen

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 762. doi:

Preconditioning Across Generations: Intermittent Hypoxia in F0 Mice Promotes Neuroprotection from Retinal Ischemia in F1 Offspring Open Access

Jeff Gidday; Krystal C Belmonte; Nicholas A Lanson; Jarrod C. Harman

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 763. doi:

Photoreceptor glucose metabolic modulation by adiponectin prevents hyperglycemic ROP Open Access

Zhongjie Fu; Chatarina Lofqvist; Raffael Liegl; Zhongxiao Wang; Ye Sun; Yan Gong; Chi-Hsiu Liu; Bertan Cakir; Rubi Duran; Alexander Poblete; Steve S Cho; James D Akula; Michael Kinter; Saswata Talukdar; Ann Hellstrom; Lois E. H. Smith

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 764. doi:

Progenitor cell combination normalizes pericyte ensheathment in the oxygen-induced retinopathy (OIR) model Open Access

Sergio Li Calzi; Lynn C Shaw; William C Shelley; Judith Quigley; Leni Moldovan; Mircea Ivan; Michael E Boulton; Mervin C Yoder; Maria Grant

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 765. doi:

Endothelial Semaphorin 6A promotes retinal revascularization and decreases pathologic angiogenesis in oxygen-induced retinopathy Open Access

Yanhong Wei; Junsong Gong; Zhenhua Xu; Elia J Duh

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 766. doi:

Myeloid precursors develop into endothelial progenitor cells modulated by SOCS3 Open Access

Ye Sun; PingZhu Zhou; Chi-Hsiu Liu; Yan Gong; Bertan Cakir; Steve S Cho; Alexander Poblete; Rubi Duran; Jing Chen; Lois E. H. Smith

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 767. doi:

Synthetic compound MAF20170220-4 Protects Human Retinal Pigment Epithelial Cells from Oxidative Stress-induced Cell Death Open Access

Lucian Del Priore; Hui Cai; Jie Gong; Laura Abriola; Mark Anthony Fields

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 768. doi:

The pro-cell death RIP1 kinase mediates angiogenesis by facilitating M2-like macrophages Open Access

Takashi Ueta; Kenji Ishihara; Shoji notomi; Jong-Jer Lee; Daniel Maidana; Nikolaos Efstathiou; Yusuke Murakami; Eiichi Hasegawa; Joan W Miller; Demetrios Vavvas

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 769. doi:

Systemic dendrimer-triamcinolone therapy for age-related macular degeneration Open Access

Kannan Rangaramanujam; Siva Pramodh Kambhampati; Imran Ahmed Bhutto; Tony P Wu; Scott McLeod; Gerard A Lutty

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 770. doi:

Effects of Anti-VEGF and ALG-1001 on Human Retinal Cells in vitro Open Access

Cristina M Kenney; Marilyn Chwa; Javier Cáceres-del-Carpio; Deepika Malik; Shari Atilano; Kevin Schneider; G. Astrid Limb; David S Boyer; Anthony B Nesburn; Baruch D Kuppermann

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 771. doi:

Aflibercept does not inhibit normal retinal vascular development in the mouse model of oxygen-induced retinopathy Open Access

Jade Gieseke Gieseke Guevara; Andres Gonzalez; Clay Clay Smith; Swati Agarwal-Sinha; Sarina Amin

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 772. doi:

Alpha-1 antitrypsin ameliorates retinal degeneration by modulating microglia polarization in rd1 mice model

Open Access

Tian Zhou

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 773. doi:

Characteristics of retinopathy associated with the use of binimetinib (MEK inhibitor) in the treatment of metastatic cancers Open Access

Chi Yun Doreen Ho; Anna Song; Lyndell L Lim; Elizabeth Dang; Dustin Pomerleau; Robert Charles Andrew Symons

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 774. doi:

Analyses of the UK Biobank data highlights hundreds of genetic loci and pathways associated with refractive error and myopia Open Access

Christopher J Hammond; Pirro G Hysi; Anthony Khawaja; Paul J Foster; Phillippa Cumberland; Peng Tee Khaw; Jugnoo Rahi

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 775. doi:

Genome-wide association studies for corneal and refractive astigmatism in UK Biobank demonstrate a shared role for myopia susceptibility loci Open Access

Rupal Lalit Shah; Jeremy A Guggenheim

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 776. doi:

Circulating O-methylascorbate is associated with population IOP variation: a metabolomics and GWAS study Open Access

Pirro G Hysi; Tim Spector; Christopher J Hammond

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 777. doi:

Association of Glaucoma-Susceptible Genes to Retinal Nerve Fiber Layer Thickness in Two Racial/Ethnic Populations in the US Open Access

Xuejuan Jiang; Darryl Nousome; Roberta McKean-Cowdin; Bruce Burkemper; Mina Torres; Rohit Varma

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 778. doi:

Polygenic risk score is associated with intraocular pressure and improves glaucoma prediction in the UK Biobank cohort Open Access

X. Raymond Gao; Fangda Fan

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 779. doi:

Statistical approaches to the analysis of whole-genome sequencing in autosomal-dominant macular dystrophy Open Access

Roberto Y Cordero; Robert W. Williams; Michael B. Petersen; Haris Kokotas; Maria Grigoriadou; George Kitsos; Nawajes A Mandal; Claire L. Simpson

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 780. doi:

GWAS identifies 52 genomic regions associated with iris colour in a study conducted using almost 200,000 participants of European descent Open Access

Mark James Simcoe; Manfred Kayser; Tim Spector; Christopher J Hammond; Pirro G Hysi

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 781. doi:

Short-Term Oral Mifepristone for the Treatment of Central Serous Chorioretinopathy (STOMP CSC) – A Randomized, Placebo-Controlled Study Open Access

Roger A Goldberg; Jeffrey S. Heier

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 782. doi:

Baseline characteristics associated with good visual acuity outcomes in myopic choroidal neovascularization: results from the RADIANCE trial Open Access

Carolyn Pan; Diana V Do; Lauren Hill; Tatiana Ecoiffier; Ivaylo Stoilov

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 783. doi:

Long-term outcomes in ranibizumab-treated East Asian patients with myopic choroidal neovascularization in the 36-month post-RADIANCE study period Open Access

Mark Wieland; Bann-mo Day; Tatiana Eccoffier; Shamika Gune; Zdenka Haskova

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 784. doi:

Retinal thickness changes and fovea migration in eyes with idiopathic macular hole after vitrectomy with hemi-temporal internal limiting membrane peeling Open Access

Jiro Kogo; Akira Shiono; Hiroki Sasaki; tatsuya jujo; Hitoshi Takagi

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 785. doi:

A Novel Contrast Sensitivity Test as a Measure of Functional Vision in Macular Telangiectasia and Central Retinal Vein Occlusion Open Access

Rebecca F Silverman; Ines Lains; Ava K Bittner; Luis A Lesmes; John B Miller

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 786. doi:

Regions of Disease Sparing Spatially Correlate with Choroidal Thinning in ABCA4 Disease Open Access

Winston Lee; Maarjaliis Paavo; Jana Zernant; Stephen H. Tsang; Janet R Sparrow; Rando Allikmets

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 787. doi:

Static and dynamic assessment of fixation stability in Stargardt disease Open Access

Etienne M Schonbach; Artur V Cideciyan; Mohamed A Ibrahim; Rupert Wolfgang Strauss; David G Birch; Janet S Sunness; Srinivas R. Sadda; Hendrik P Scholl

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 788. doi:

Whole-exome sequencing in age-related macular degeneration identifies rare protein-altering variants in COL8A1, a component of Bruch’s membrane Open Access

Anneke I Den Hollander; Jordi Corominas; Johanna Maria Colijn; Maartje Geerlings; Sascha Fauser; Eiko de Jong; Cornelia van Duijn; Carel C B Hoyng; Caroline C W Klaver

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 789. doi:

Functional Analysis of the Complement Inhibitor Factor I in Sera of Patients with Advanced Age-Related Macular Degeneration Open Access

Peter Baciu; Jae Yang; David Kavanagh; John Atkinson; Johanna Seddon

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 790. doi:

C3a triggers formation of sub-RPE deposits via the ubiquitin proteasome pathway. Open Access

Rosario Fernandez-Godino; Eric A Pierce

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 791. doi:

Complement activation products, single nucleotide polymorphisms and age-related macular degeneration (AMD). Open Access

Baerbel Rohrer; ashley Frazer-Abel; Anthony Leonard; Rinki Ratnapriya; Tyson Ward; Alexandra Pietraszkiewicz; Elizabeth O’Quinn; Katherine Adams; Anand Swaroop; Bethany Wolf

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 792. doi:

Impact of lactate transport deficit in age-related macular degeneration Open Access

Laurence Klipfel; Mélanie Var; Marie Cordonnier; Saddek Mohand-Saïd; Olivier Goureau; Thierry D. Leveillard

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 793. doi:

Damaged nuclear DNA accumulates in retinal pigment epithelium cells of age-related macular degeneration patients Open Access

Haijiang Lin; Bo Tian; ahmad Al-moujahed; Joan W Miller; Demetrios G. Vavvas

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 795. doi:

Retinal Ganglion Cell Recovery Open Access

Jonathan G Crowston

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 796. doi:

Energy supply to optic nerve axons Open Access

Peter van Wijngaarden

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 797. doi:

The MATE study: Treating neovascular age- related Macular degeneration with Aflibercept: a pilot, 24 month randomised controlled trial comparing standard care with individualised Treat an... Open Access

Archana Airody; Tracey Dorey; Aleksandra Mankowska; Konstantinos Balaskas; Raj Mukherjee; Theo Empeslidis; Louise Downey; Sushma Dhar-munshi; Antony Morland; Heidi Baseler; Richard Gale

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 798. doi:

One-year real-world outcome in patients receiving individualized treatment with aflibercept for neovascular age-related macular degeneration Open Access

Mya Thida Ohn

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 799. doi:

Assessment of Mental Burden of Patients with Neovascular Age-Related Macular Degeneration Treated by Treat-and-Extend Regimen with Intravitreal Ranibizumab Open Access

Aki Kato; Tsutomu Yasukawa; Iichiro Sugita; Munenori Yoshida; Miho Nozaki; Yoshio Hirano; Junko Kondo; Tomohiro Abe; Kimiko Sugita; Takahide Okita; Hiroshi Morita; Kazuhiko Sugitani; Hideaki Usui; Naomi Niwa; Fusae Kato; Yuichiro Ogura

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 800. doi:

Treatment of neovascular Age related macular degeneration (AMD) using a Modified ‘Treat and Extend regimen’ Open Access

Rehab Ismail; Deepali Varma

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 801. doi:

AMD associated Peripapillary Choroidal Neovascularization in the era of anti-VEGF therapy Open Access

Tiezhu Lin; Kunny C Dans; Amit Meshi; Manuel Amador; William R Freeman

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 802. doi:

Prospective Randomized Controlled Trial of Combination Ranibizumab and Indomethacin for Neovascular Age-Related Macular Degeneration Open Access

Andrea Russo; Elena Gambicorti; Francesco Morescalchi; Francesco Semeraro

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 803. doi:

Psychometric properties of the National Eye Institute Visual Function Questionnaire (NEI-VFQ 25) tested in observational longitudinal study of patients with neovascular Age-related Macula... Open Access

Elma Jelin; Torbjørn Wisløff; Morten C Moe; Turid Heiberg

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 804. doi:

Comparison of Physician and Nurse-Administered Intravitreal Injections of anti-vascular endothelial growth factor, a Randomized Noninferiority Trial. Open Access

Stine Bolme; Tora Sund Morken; Turid Follestad; Vidar Halsteinli; Dordi Austeng

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 805. doi:

Factors to consider before switching anti-VEGF treatments in neovascular age-related macular degeneration (nAMD): Effect of online education on physician knowledge and confidence Open Access

Siggi D Trier; Anat Loewenstein; Deborah Middleton; Peter Schoonheim

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 806. doi:

Three-year outcomes of a treat and extend regimen of aflibercept for neovascular age-related macular degeneration Open Access

Mio Hosokawa; Yuki Morizane; Shuhei Kimura; Yusuke Shiode; Masayuki Hirano; Shinichiro Doi; Shinji Toshima; Kosuke Takahashi; Atsushi Fujiwara; Yuki Kanzaki; Mika Hosogi; Fumio Shiraga

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 807. doi:

Eight-year outcome in the first cohort of ranibizumab-treated patients at Northampton General Hospital, United Kingdom Open Access

Lin Lu; Lina Osman; Prabhu Tonne; Gopinath Reddy; Maharatnam Logendran

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 808. doi:

Anti-VEGF Therapy Patterns of Neovascular Age-related Macular Degeneration in Shanghai, China Open Access

Mengxi Shen; Tianyuan Zhou; Chunyu Fu; Xiang Gu; Meichun Xiao; Fenghua Wang; Xiaodong Sun

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 809. doi:

Retrospective Evaluation of Neovascular Age-related Macular Degeneration Managed With Treat-And-Extend Regimen: 5-year Results of the RENO Study Open Access

Micaela Koci; Greggory M Gahn; Peter D Freeman; Lauren Hill; Sarah A Taylor; Aamir Aziz; Arshad M. Khanani

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 810. doi:

One-year Outcomes of Fixed Treatment of Intravitreal Aflibercept for Exudative Age-related Macular Degeneration and the Factor of Visual Prognosis
Open Access

Rie Osaka; Chieko Shiragami; Aoi Ono; Saki Manabe; Yukari Takasago; Mamoru Kobayashi; Ayana Yamashita; Kazuyuki Hirooka

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 811. doi:

Risk factors for breakthrough vitreous hemorrhage after intravitreal anti-VEGF injection in age-related macular degeneration Open Access

Yong-Il Shin; Jae-Yun Sung; Jung-Yeul Kim

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 812. doi:

Systemic risk factors that may impinge on the therapeutic outcomes in neovascular age related macular degeneration treated with anti VEGF agents on a treat and extend regimen Open Access

Yi Fan Tang; Kanishka Randev Mendis

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 813. doi:

Evolution over 4 years of enrollment of baseline characteristics of treatment-naïve nAMD patients in the LUMINOUS study Open Access

Eric H Souied; Wayne Macfadden; Soumil Parikh

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 814. doi:

Ranibizumab and Aflibercept: Baseline and 12-month visual outcomes of patients at a large tertiary ophthalmic hospital Open Access

Siegfried K Wagner; Katrin Fasler; Farid Afshar; Reena Chopra; Karsten Ulrich Kortuem; Nikolas Pontikos; Thushanthi Ramakrishnan; Ella Preston; Praveen Patel; Adnan Tufail; Konstantinos Balaskas; Pearse Andrew Keane

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 815. doi:

Development of neovascular age-related macular degeneration in fellow eyes of patients undergoing intravitreal anti-VEGF therapy at a large tertiary ophthalmic hospital Open Access

Reena Chopra; Siegfried K Wagner; Katrin Fasler; Karsten Ulrich Kortuem; Nikolas Pontikos; Farid Afshar; Thushanthi Ramakrishnan; GABRIELLA CLAIRE PRESTON; Konstantinos Balaskas; Praveen Patel; Adnan Tufail; Pearse Andrew Keane

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 816. doi:

Intravitreal aflibercept treatment in a population of different subtypes of exsudative maculopathy Open Access

Guenther Weigert; Sandra Rezar; Katharina Eibenberger; Wolf Buehl; Ursula Schmidt-Erfurth; Stefan Sacu

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 818. doi:

Influence of posterior vitreous detachment on extendability of treat-and-extend anti-VEGF therapy in neovascular age-related macular degeneration Open Access

Sophie Klimscha; Léon Coulibaly; Amir Sadeghipour; Bianca S Gerendas; Sebastian M Waldstein; Ursula Schmidt-Erfurth

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 819. doi:

LONG-TERM OUTCOMES OF SWITCHING TO AFLIBERCEPT FOR TREATMENT RESISTANT NEOVASCULAR AGE-RELATED MACULAR DEGENERATION Open Access

Kimberly Spooner; Thomas Hong; Rashmi Nair; Nicholas Chian Chiang Chow; Geoffrey Broadhead; Wijeyanthy Wijeyakumar; Andrew Chang

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 820. doi:

Investigating visual and anatomical outcomes of patients treated with ranibizumab and aflibercept for wet macular degeneration in the United Kingdom over a 3 year period Open Access

Michael Grinton; Michael McKenna; Sreekumari Pushpoth; Philip Severn

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 821. doi:

Risk for low visual acuity after 1 and 2 years of treatment with anti-VEGF. Comparison of different agents: Ranibizumab, Aflibercept, and Bevacizumab Open Access

Inger Westborg; Aldana Rosso

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 822. doi:

Long-term analysis of intravitreal anti-VEGF drugs Open Access

Tetsuhiro Yasuma; Keiko Kataoka; Yasuki Ito; Hiroko Terasaki

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 823. doi:

Quarterly Anti-VEGF Dosing for the Treatment of Neovascular Age-Related Macular Degeneration: A Cross Trial Comparison Open Access

David Aaron Eichenbaum; Bann-mo Day; Lisa Tuomi

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 824. doi:

Long-term visual and anatomical outcomes in treatment naïve neovascular age-related macular degeneration (nAMD) patients treated with anti-VEGF agents Open Access

Saleema A. Kherani; Roomasa Channa; Rimsha Shaukat; Olukemi Adeyemo; Mustafa Iftikhar; Adrienne Scott; Akrit Sodhi; James T Handa; Ingrid Zimmer-Galler; Adam Wenick; Sharon D Solomon; Mira Sachdeva; Catherine B Meyerle; Peter A Campochiaro

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 825. doi:

One and two-year visual acuity outcomes after treatment for neovascular age-related macular degeneration at a large tertiary ophthalmic hospital Open Access

Katrin Fasler; Farid Afshar; Reena Chopra; Karsten Ulrich Kortuem; Nikolas Pontikos; Siegfried K Wagner; Laxmi Raja; Hasaneen Al Janabi; Thushanthi Ramakrishnan; GABRIELLA CLAIRE PRESTON; Konstantinos Balaskas; Adnan Tufail; Praveen Patel; Pearse Keane

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 826. doi:

Evaluation of intravitreal aflibercept for treatment-naïve eyes with retinal angiomatous proliferation (RAP) using a fixed regimen during the first year of treatment Open Access

Jan Ernest; Katerina Manethova; Petr Kolar

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 827. doi:

Outcome of Avastin treatment for wet age-related macular degeneration in patients with visual acuity score 85 or better at first presentation Open Access

Ben J L Burton; Tahmina Parveen

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 828. doi:

A Probabilistic Forecast of 12 Month Visual Outcomes of nAMD Open Access

Vuong Nguyen; Kelvin Teo; Judy Simpson; Vincent Daien; Daniel Barthelmes; Mark C Gillies; Richard Walton

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 829. doi:

Comparison of initially on-scheduled versus delayed versus missed ranibizumab treatment in neovascular age-related macular degeneration Open Access

Yi-Sheng Chang

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 830. doi:

Efficacy and safety of ranibizumab with or without verteporfin photodynamic therapy for polypoidal choroidal vasculopathy: 24-month results from the EVEREST II study Open Access

Adrian H C Koh; Soumil Parikh

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 831. doi:

Examination of the effect of topical aqueous suppressants on the efficacy of anti-VEGF infections for age-related macular degeneration Open Access

Jonathan Minkowski; Mathew MacCumber

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 832. doi:

Clinical Characteristic of and Anti-VEGF Resistance in Polypoidal Choroidal Vasculopathy in Caucasian Patients Open Access

Gregg T. Kokame; Kelli Kokame; Keke Liu; Kyle Kaneko

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 833. doi:

Outcomes in Eyes with Retinal Angiomatous Proliferation treated with different anti-VEGF regimens Open Access

Elizabeth M Walsh; Sumith Perera; Ramez Borbara; Gabriella De Salvo

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 834. doi:

Visual Outcome of Bilateral Same-Session Intravitreal Anti-VEGF Injections Open Access

Saghar Bagheri; Ismini Koulouri; Eleni Konstantinou; Feyza Erenler; Demetrios G. Vavvas

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 835. doi:

Association Between Timing of Peak Vision Gain and Long-Term Outcomes of Ranibizumab for nAMD: A Post Hoc Analysis of HARBOR Open Access

Louis Chang; Rahul N. Khurana; Bann-mo Day; Avanti Ghanekar; Ivaylo Stoilov

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 836. doi:

Ranibizumab treatment for nAMD in clinical practice: outcomes from the LUMINOUS™ study Open Access

Sanjay Sharma; Soumil Parikh; Wayne Macfadden

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 837. doi:

Visual outcomes after 50 or more intravitreal anti-VEGF injections for neovascular age-related macular degeneration at a large tertiary ophthalmic hospital Open Access

Karsten Ulrich Kortuem; Thushanthi Ramakrishnan; Katrin Fasler; Reena Chopra; NIKOLAS PONTIKOS; Siegfried Wagner; Laxmi Raja; Hasaneen Al Janabi; Farid Afshar; Ella Preston; Praveen Patel; Adnan Tufail; Konstantinos Balaskas; Pearse Keane

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 838. doi:

Real world data of Anti-VEGF treatment (Aflibercept) in treatment naive Neovascular Age Related Macular Degeneration (nAMD) over 3 years Open Access

Manju Chandran; Sidharth Praveen; Lorraine North; Hasan Naveed; Leena Bhat; Sely Mathew; Narendran Nair; Geeta Menon

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 839. doi:

Comparison of Ranibizumab and Aflibercept in Patients with Neovascular Age-Related Macular Degeneration treated following a ‘Treat and Extend’ protocol: efficacy variables from the pre-sp... Open Access

Mark C Gillies; Alex Hunyor; Jennifer Arnold; Francois Pecheur; Kathryn Underhill; Robyn H Guymer; Ian McAllister

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 840. doi:

Comparison of Outcomes in Patients with Neovascular Age-Related Macular Degeneration Managed with Anti-VEGF on Conventional Treat-and-Extend vs. Trial-Stop Regimens Open Access

Christina Y Weng; Weijie Violet Lin

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 841. doi:

Assessment of Fluorescein Angiographic Pattern and Its prognostic value in Idiopathic Epiretinal Membrane
Open Access

Ik Soo Byon; Hanjo Kwon; Sungwho Park; Ji Eun E Lee

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 842. doi:

Effect of lubricants on corneal thickness during pars plana vitrectomy Open Access

Diane Siegel; Andrew Hendrick

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 843. doi:

Visual and Anatomic Outcomes of Pediatric Endoscopic Vitrectomy in 210 Consecutive Cases Open Access

Unikora Yang; Aaron Nagiel; Sui Chien Wong; Emil Anthony Say; Thomas C Lee

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 844. doi:

Comparison of outcomes between 20, 23 and 25 gauge vitrectomy for dropped lens fragments during cataract surgery. Open Access

Seung Lee

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 845. doi:

Comparison of Visual and Anatomic Outcomes of Eyes Undergoing Type I Boston Keratoprosthesis with Combination Pars Plana Vitrectomy to Eyes without Combination Vitrectomy Open Access

Jennifer I Lim; Lindsay Machen; Andrea Arteaga; Faris Karas; Robert A Hyde; Dingcai Cao; Marcia Niec; Thasarat S Vajaranant; Maria Soledad Cortina

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 846. doi:

Foveal architectural alterations following internal limiting membrane peeling for high myopic retinoschisis identified with intraoperative optical coherence tomography Open Access

Yuji Ito; Makoto Inoue; Akito Hirakata

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 848. doi:

Inflammatory destruction of the RPE of an autologous RPE and choroid graft ? Open Access

Jan C van Meurs; Saskia HM van Romunde; Elsbeth T J van Zeeburg; Grazia Pertile

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 849. doi:

Outcomes of 25 or 27 Ga PPV and Akreos AO60 secondary lens implantation performed by trainees with supervision Open Access

Michael J Ang; Poorav Patel; Judy J Chen; Arthur D Fu

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 850. doi:

Dynamic Changes in Temperature and Condensation on Intraocular Lenses During Air-Fluid Exchange Open Access

Darren Knight; Sean Tsao; Steven Carter; Mitul C Mehta; Baruch D Kuppermann

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 851. doi:

The impact of early vitrectomy for dense vitreous hemorrhage without a history of diabetic retinopathy. Open Access

Mayuka Hayashida; Akiko Miki; Hisanori Imai; Atsushi Azumi; Makoto Nakamura

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 852. doi:

Long-term outcome of idiopathic macular hole vitrectomy without postoperative face-down positioning Open Access

Fumihiko Yagi; Tetsuro Takumi; Goji Tomita

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 854. doi:

Correlation between choroidal thickness and intraocular pressure after 23-gauge and 25-gauge vitrectomy for idiopathic epiretinal membrane Open Access

Asuka Takeyama; Yutaka Imamura; Masaki Shibata; Yuko Komiya; Goji Tomita; Masahiro Ishida

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 855. doi:

Clinical and Anatomic Outcomes of Phacovitrectomy Surgery in Proliferative Diabetic Retinopathy Open Access

Talisa E de Carlo; Shilpa Gulati; Ivy Zhu; Elmer Tu; William F Mieler

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 856. doi:

Augmented Posterior Hyaloid Adhesion Associated with Retinal Detachment after Macular Hole Repair Open Access

Danielle M Lo; Michael R Chua; Kenneth J Wald

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 857. doi:

A randomized controlled clinical trial comparing 20 gauge and 23 gauge vitrectomy for patients with macular hole or macular pucker Open Access

Paula Scholz; Philipp Müther; Petra Schiller; Moritz Felsch; Sascha Fauser

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 858. doi:

Clinical outcomes and safety profile of scleral fixated AKREOS AO60 lens Open Access

Nour Nofal; Ali Dirani; Karim Hammamji

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 859. doi:

Narcotic Prescribing Patterns and Pain Management by Vitreoretinal Surgeons Open Access

Kinley Beck; Petar Yanev; Tyson Jergensen; Joshua Iltis; Raul Membreno; Kendall Wannamaker; patricia rosales; jeong-hyeon sohn; Roberto Diaz-Rohena; Michael Singer

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 860. doi:

Vitrectomy without Prone Positioning for Rhegmatogenous Retinal Detachments in Eyes with Inferior Retinal Breaks Open Access

Susumu Sakimoto; Nobuhiko Shiraki; Hirokazu Sakaguchi; Kentaro Nishida; Kohji Nishida; Motohiro Kamei

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 861. doi:

Predictive factors for better short-term outcome in idiopathic epiretinal membrane after pars plana vitrectomy Open Access

Sakiko Minami; Yuta Shigeno; Hajime Shinoda; Norihiro Nagai; Toshihide Kurihara; Mamoru Kamoshita; Kazuhiro Watanabe; Hideki Sonobe; Yuki Hidaka; Kazuo Tsubota; Yoko Ozawa

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 862. doi:

Clinical and pathological observation of retinal changes after vitrectomy with internal limiting membrane peeling Open Access

Toshio Hisatomi; Takashi Tachibana; Shoji notomi; Kohta Fujiwara; Yusuke Murakami; Yasuhiro Ikeda; Shigeo Yoshida; Tatsuro Ishibashi; Koh-hei Sonoda

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 863. doi:

The Double-edged Sword of Epiretinal Membrane Surgery: Improving Versus Inducing Diplopia Open Access

Raymond Iezzi; Sarah R Hatt; David A Leske; Jonathan M Holmes

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 864. doi:

The Inner Limiting Membrane Peel without special staining for Macular Pucker Removal Open Access

Andrew Hou; Kevin Leikert; Paul Hanona; Bianca Kizy; Nathan Farley; Hua Gao

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 865. doi:

Topical Aqueous Suppression and Spontaneous Closure of Idiopathic Full-Thickness Macular Holes Open Access

Daniel Su; Anthony Obeid; Jason Hsu

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 866. doi:

The Treatment of Large Macular Hole using Multi-Layered Inverted ILM Flap Technique Open Access

Jung Min Park; Dong hun Song; Myeong In Yeom; Soo Jung Lee

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 867. doi:

Comparative outcomes of same-day versus day one postoperative examinations following vitreoretinal surgery Open Access

Sherveen Shayegan Salek; Hannah Lee Park; Andrew Hendrick

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 868. doi:

Macular Buckling Versus Vitrectomy for Myopic Macular Schisis and associated macular Detachment Open Access

Lin Lu; Bingqian Liu; Yonghao Li; Wei Ma; Xiling Yu

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 869. doi:

Comparison of intraocular pressure fluctuation during pars plana vitrectomy performed with various vitrectomy systems Open Access

YOICHIRO SHINKAI; Kazuhito Yoneda; Chie Sotozono

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 871. doi:

Quantitative Evaluation of Digital-Image Enhancement during Heads-Up Surgery Open Access

Kunihiko Akiyama; Ken Watanabe; Masaki Fukui; Hiroshi Higuchi; Yasufumi Fukuma; Toru Noda

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 872. doi:

Preferred practice patterns among young retina specialists Open Access

Angeline L. Wang; Jonathan Tsui; Hemang K. Pandya; Mitul C. Mehta

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 873. doi:

Incidence of pars plana vitrectomy for complications related to proliferative diabetic retinopathy in patients previously treated with panretinal photocoagulation. Open Access

Ian D Kirchner; John P. McLaughlin; Bao Dinh; Philip Henry Scharper

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 874. doi:

Scleral fixation of posterior chamber intraocular lenses using Gore-Tex suture: clinical outcomes from a single-institution case series Open Access

Andrew M. Williams; Benjamin Botsford; Ian Conner; Andrew W Eller; Joseph Martel

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 875. doi:

Clinical and Anatomic Outcomes of Combined Phacovitrectomy Surgery Open Access

Shilpa Gulati; Talisa E de Carlo; Ivy Zhu; Elmer Tu; William F Mieler

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 876. doi:

Dynamic Anatomic Changes During Epiretinal Membrane Peeling Surgery Measured Using Intraoperative OCT Open Access

Lekha Mukkamala; Parisa Emami-naeini; Sophia Wong; David Cunefare; Sina Farsiu; Lawrence S Morse; Ala Moshiri; Susanna S Park; Glenn Yiu

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 877. doi:

Optical coherence tomography angiography of dissociated optic nerve fiber layer appearance after internal limiting membrane peeling for full thickness macular hole
Open Access

Nathan Schuck; Morgan Heisler; Sherry Han; Marinko Sarunic; Eduardo Vitor Navajas

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 879. doi:

Posterior-involving open-globe injury prognostic factors and outcomes Open Access

Levi Kanu; Yi Jiang; William F Mieler

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 880. doi:

Inverted flap for large macular holes: a functional evaluation Open Access

salvatore parrulli; Isabella D'Agostino; Ugo Nava; Matteo Giuseppe Cereda; Giovanni Staurenghi

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 882. doi:

Post-vitrectomy ocular hemorrhage among United States adults on oral antithrombotics Open Access

Ronald A Cantrell; Jeffrey Ryuta Willis; Susanna S Park; Yifeng Chia; Mariam Abouhossein; Giulio Barteselli

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 883. doi:

Outcomes of 27-gauge pars plana vitrectomy for diabetic vitreoretinal disease Open Access

Megan Nichols; Rebecca M Sieburth; Yevgeniy Shildkrot

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 884. doi:

Clinical outcome comparison of vitrectomy for myopic traction maculopathy according to the international photographic classification for myopic maculopathy Open Access

Kyungsik Lee; Euichun Kang; Hyoungjun Koh

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 885. doi:

Outcomes of Vitrectomy in Von Hippel-Lindau Disease Open Access

Matthew Armstrong Powers; Ryan A Shields; Cassie Ann Ludwig; Darius M. Moshfeghi

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 886. doi:

Development, Implementation, and Evaluation of a Pre-Residency Vitreoretinal Curriculum for Ophthalmology Residents Using the American Academy of Ophthalmology’s Ophthalmology News and Ed... Open Access

Robison Vernon Paul Chan; Lindsay Machen; Karyn Jonas; Ahmad Aref

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 888. doi:

Immunolocation of aquaporin 1 and aquaporin 8 in lens Open Access

Rijo Hayashi; Shimmin Hayashi; Kazunori Fukuda; Shigeki Machida

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 889. doi:

Tropomyosin is required for normal lens development and differentiation Open Access

Eri Kubo; Teppei Shibata; Etsuko Kiyokawa; Masahito Ikawa; Dhirendra P Singh; Hiroshi Sasaki

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 890. doi:

Wnt5a through noncanonical Wnt/JNK signaling promotes the differentiation of human embryonic stem cells to lentoid bodies Open Access

Chenlu Han; Jinyan Li; Chunxiao Wang; Lixia Luo

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 891. doi:

Investigation of differentiation and cell junctions in 3D Spherical Micro-Chambered Lens Epithelial Cells In vitro Open Access

Chun-Yen Liu; Eddie Wang; Nikki Tjahjono; Chun-hong Xia; Xiaohua Gong

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 892. doi:

Spred: A regulator of lens epithelial cell proliferation and fiber differentiation.
Open Access

Fatima Wazin; Frank J Lovicu

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 893. doi:

Transcriptome landscape of early lens development Open Access

Salil Anil Lachke; Atul Kakrana; Archana D Siddam; Irfan Saadi; Deepti Anand

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 894. doi:

Investigation of proteins interacting with the cataract-linked RNA-binding protein Celf1 in mouse lens development Open Access

Sandeep Aryal; Archana D Siddam; Salil Anil Lachke

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 895. doi:

Long-term Ocular Developmental Changes in Children following Cataract Surgery Open Access

Shagun Dhaliwal; David McCartney; Kelly Mitchell; Rachel Cooley; Derek Han; Suzette Luke; Lingkun Kong

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 897. doi:

Ocular surface microbiomes of children and adults Open Access

Coby Ray; Kelly Mitchell; Elisa Morales; Declan Kirk; Lesley Motheral; Elisabeth Conser; Tammy Camp; Ted W Reid; Phat Tran; Keaton Luth; David McCartney; Bryson Tudor; Eric Nieto; Michael Maldonado; Olof Sundin

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 899. doi:

Staphylococcus aureus lysates inhibit HSV-I infection in conjunctival epithelial cells Open Access

Kaili Wu; Tianlan Lin; Xiuping Liu; Yafang Zhang; Minyi Zhu

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 901. doi:

Impact of contact lens wear and dry eye on the amicrobiomic status of the murine cornea Open Access

Stephanie Wan; Matteo Metruccio; Abby Kroken; Melinda Grosser; David J Evans; Suzanne M J Fleiszig

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 902. doi:

Ocular Demodicosis is Associated with Changes of Ocular Surface Microbiota
Open Access

Xiaohui Luo; Yan Liu; Lai Wei; Lingyi Liang

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 903. doi:

Determining the Ideal Swab Material for Analyzing the Ocular Surface Microbiome Open Access

Kara Marie Cavuoto; Anat Galor; Darlene Miller; Santanu Banerjee

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 904. doi:

In-Vitro Demodicidal Activity of Commercial Lid Hygiene Products Open Access

Alan G Kabat

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 905. doi:

Acute sunburn of human eye – microstructural observations by in vivo confocal microscopy
Open Access

Christina N Grupcheva; Dimitar Grupchev; Mladena N Radeva

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 906. doi:

Microbial Contamination in Corneas Stored in Organ Culture Media: A 30 Month Report from the Lions New South Wales Eye Bank Open Access

Meidong Zhu; Matthew Wells; Morgan Kennedy; Rajnesh Devasahayam; Pierre Georges; Mona Ghabcha; Jane Treloggen; Gerard Sutton; Con Petsoglou

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 907. doi:

What is hiding in your eyes? The microbiome of ocular surface niches Open Access

Jerome Ozkan; Mark Willcox; Bernd Wermeuer; Torsten Thomas; Minas T Coroneo

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 908. doi:

Noninvasive assessment of tear film break-up time and location in normal subjects and patients with dry eye syndrome Open Access

Ran Zhuo; Jun Jiang; Lijie Hou; Xinjie Mao; Fan Lu; Bin Zhang

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 909. doi:

Isolation and Analysis of Normal Human Tear Extracellular Vesicle RNA Open Access

Henry Fortinberry; William Ngo; Cameron Postnikoff; Jason J Nichols; Andrew Pucker

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 910. doi:

EQUIVALENCE OF LIPID LAYER PATTERNS OBTAINED FROM TWO DIFFERENT INTERFEROMETERS AND GRADED WITH TWO SCALES Open Access

Maria Vidal-Rohr; Leon N Davies; James Stuart Wolffsohn

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 911. doi:

Changes in Signs and Symptoms of Dry Eye Disease after using 0.1% or 0.05% Emulsions of Cyclosporine A Eye Drops Open Access

Jonatan Olafsson; Øygunn Aass Utheim; Xiangjun Chen; Snorri Olafsson; Sten Raeder; Darlene A Dartt; Behzod Tashbayev; Tor Paaske Utheim

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 912. doi:

Smartphone use and effects on tear film, blinking and binocular vision. Open Access

Blanka Golebiowski; Jennifer Long; Kirsten Harrison; Abigail Lee; Lisa Asper

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 913. doi:

Evaluation of the Durability of Dry Eye Symptom Relief Following Daily Use of TrueTear™ Open Access

Jeff Penzner; David Hollander; Gail Torkildsen; Stephanie Baba; Mark Holdbrook; Michelle Senchyna

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 914. doi:

Effectiveness of Trehalose 3% as a treatment for Dry Eye Syndrome in patients with Sjögren's Syndrome Open Access

Alejandro Navas; Ariadna Benitez-García; CHRISTIAN DENISSE PINKUS HERRERA; Juan Carlos Serna-Ojeda; Arturo J Ramirez-Miranda; Enrique O Graue-Hernandez

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 915. doi:

Meibomian gland dysfunction and dry-eye syndrome in type 2 diabetic patients Open Access

Ji Yoon Kwak; Tae Hun Kim; Seung Min Lee; Kyung Eun Han; Roo Min Jun

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 916. doi:

Temporal change in clinical dry eye metrics of chronic ocular graft-versus-host disease (OGVHD) after allogeneic hematopoietic stem cell transplantation (allo-HSCT) Open Access

Cynthia Tung

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 917. doi:

Effect of TrueTear™ on Dry Eye Symptoms During Exposure to a Controlled Adverse Environment Open Access

Michelle Senchyna; George W Ousler; Gary Jerkins; Guruprasad Pattar; David Evans; Mark Holdbrook; Stephanie Baba

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 918. doi:

Conjunctival epithelial cell HLA-DR expression and association with signs and symptoms of Dry Eye Disease (DED) in the ‘Dry Eye Assessment and Management’ (DREAM^©) Study. Open Access

Neeta S Roy; Yi Wei; Eric Kuklinski; Brendan Barry; Gui-Shuang Ying; Yinxi Yu; Maureen G. Maguire; Mary Brightwell-Arnold; Penny A Asbell

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 919. doi:

Contrast Between Meibomian Gland and Background as an Objective Measure of Gland Function Open Access

Thao N Yeh; Meng C Lin

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 920. doi:

Prevalence of Meibomian Gland Dysfunction in Sjogren’s Syndrome Patients Open Access

Sruthi Srinivasan; Barbara Caffery; Jennifer S Harthan; Mira Acs; Melissa Barnett; Larisa Johnson-Tong; Dominik Papinski; Bart Pemberton

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 921. doi:

Efficacy of punctal cautery in chronic ocular GVHD Open Access

Matthew Viggiano; Lanyu Mi; Joanne Shen

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 922. doi:

Lid laxity and Concurrent Signs of Ocular Surface Disease Open Access

Tracy Doll; Jennifer S Harthan; Scott Schwartz; Clare Halleran; Milton M Hom

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 923. doi:

The Association between Signs and Symptoms in Patients with Dry Eye Disease Open Access

Maxwell Pistilli; Maureen G. Maguire; Jack V Greiner; Penny A Asbell

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 924. doi:

Tivanisiran, a new treatment for Dry Eye Disease, that improved signs and symptoms in clinical trials Open Access

Ana Isabel Jimenez; Veronica Ruz; Victoria Gonzalez; Covadonga Paneda; Tamara Martinez; Beatriz Vargas; Anne Marie Bleau

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 925. doi:

The correlation between the severity of dry eye and videokeratographic indices in Korea
Open Access

Byung Yi Ko; Jong-ha Lee; Min Hwan Kim; Young Hoon Lee

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 927. doi:

Prevalence of Meibomian Gland Dysfunction in a Norwegian Working-Age Population Seeking Specialist Eye Care for Dry Eye Symptoms Open Access

Reza A Badian; Tor Paaske Utheim; Sten Raeder; Øygunn Aass Utheim; Xiangjun Chen; Behzod Tashbayev; Bente Monica Aakre; Ann Elisabeth Ystenas; Vibeke Sundling

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 928. doi:

Increased Meibomian gland dropout and MMP-9 expression in an untreated millennial population who did not self-report for MGD treatment Open Access

Srihari Narayanan; Narges Kasraie; Charles G Connor; William Miller

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 929. doi:

Is significant reduction of ocular surface inflammation while applying CSA 0,1% eyedrops in patients with ocular Graft versus Host Disease (GVHD) accompanied by improvement of the Ocular... Open Access

Stephanie Weissleder; Alexander Steinhorst; Francis Ayuk Ayuketang; Stefan Linke; Nicole Stuebiger

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 930. doi:

Correlations between dry eye, ocular surface findings, autonomic and sensitive neuropathy in diabetic patients with Charcot Joint Disease Open Access

Alex Treiger Grupenmacher; Gabriel Ayub; Yeelen Ballesteros Atala; Jessica Castro; Marina Gonçalves Monteiro Viturino; Delma Huarachi; Daniel Borges; Bruna Gil Ferreira; Bruna Duarte; Maria Candida Ribeiro Parisi; Monica Alves

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 931. doi:

Interpretation of the lipid layer thickness in dry eye disease with LipiView II interferometer Open Access

Yun Jin Lee; Do Yeh Yoon; Joon-Young Hyon; Hyun Sun Jeon

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 933. doi:

A longitudinal study of the relationship between signs and symptoms in keratoconjunctivitis sicca Open Access

Jeffry Hogg; Dahlia Ismail; Jean-Sebastien Garrigue; Maëva Deniaud; Mourad Amrane; Francisco C Figueiredo

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 934. doi:

The potential effect of LipiFlow on meibomian gland structure: a preliminary analysis utilizing Dynamic Meibomian Imaging Open Access

Arjan Hura; Alice Epitropoulos; Craig Czyz; Caroline A Blackie; Tracy Davis (McClelland)

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 935. doi:

The repeatability of tear film measurements in subjects with dry eye Open Access

Fiona Stapleton; Katherine Wong; Mark Willcox; Jacqueline Tan

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 936. doi:

Prevalence of Novel Candidate Sjogren's Syndrome Antibodies in the Dry Eye Assessment and Management (DREAM^©) Study Open Access

Vatinee Y Bunya; Gui-Shuang Ying; Maureen G. Maguire; Eric Kuklinski; Ellen Peskin; Meng C Lin; Penny A Asbell

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 937. doi:

Temperature Variabilty of Beaded Heat Mask for Meibomian Gland Dysfunction Open Access

Amy Nau; Graham Stetson

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 940. doi:

Influence of perfluorohexyloctane containing eye drops on tear film thickness in patients with mild to moderate dry eye disease Open Access

Gerhard Garhofer; Doreen Schmidl; Rene Marcel Werkmeister; Narine Adzhemian; Kosobokovs Serge; Sonja Kroesser; Leopold Schmetterer

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 941. doi:

Epidemiology of persistent dry eye-like symptoms after cataract surgery Open Access

Allister Gibbons; Eugenia Iglesias; Ravin Sajnani; Roy Levitt; Konstantine sarantopoulos; Anat Galor

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 942. doi:

Relationship between subjective symptoms of dry eye disease and lifestyle habits: Large-scale clinical research using iPhone application Open Access

Takenori Inomata; Masahiro Nakamura; Yusuke Yoshimura; Masao Iwagami; Yoshimune Hirastuka; Satoshi Hori; Keiichi Fujimoto; Yuichi Okumura; Tina Shiang; Akira Murakami

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 943. doi:

Noninvasive assessment of tear film and corneal wavefront change of 3% Diquafosol ophthalmic solution for patients with dry eye after cataract surgery Open Access

Bongjoon Choi

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 944. doi:

Effect of warming eyelids on tear film stability and quality of life in visual display terminal (VDT) users: a randomized controlled trial Open Access

Chi-Chin Sun; Ching Hsi Hsiao; Chia-Yi Lee; Yih-Shiou Hwang; Tagami Kyouko; Igaki Michihito

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 945. doi:

Periocular nerve blocks for the treatment of ocular pain Open Access

leslie small; Andrew Chang; Roy Levitt; Anat Galor; Konstantine sarantopoulos

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 946. doi:

A Phase 2 randomized, double-masked, placebo-controlled study of novel narrow spectrum kinase inhibitor TOP1630 for the treatment of dry eye syndrome Open Access

Mike Taylor; Ajay Duggal; Claire Walshe; Matthew Fyfe; Adele Rowley; Steve Webber

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 947. doi:

Clinical, cytological and biochemical results of the adjuvant treatment of freeze-dried Aloe Vera gel and drops in patients with evaporative dry eye disease. Open Access

josefina A. mejias smith; Luis Izquierdo; Marta G Hadid; Carmen Maldonado; Jose A. Chauca; Maria Henriquez

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 949. doi:

Prevalence of Dry Eye Feeling and Its Associations in Russia. The Ural Eye and Medical Study
Open Access

Jost B Jonas; Mukharram Bikbov; Gyulli Kazakbaeva; Rinat Fayzrakhmanov; Yulia Uzyanbaeva; Rinat Zainullin

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 950. doi:

Does smartphone exposure time and smartphone SAR value affect ocular surface and refractive error of the dominant eye? Open Access

Sertac Argun Kivanc; Berna Akova-Budak; Mahmut O?uz Ulusoy; Arzu Seyhan Karatepe; Osman Okan Olcaysu

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 951. doi:

Evaluation of Multiple Imputation Methods for Missing Diary Data for Statistical Analysis in Dry Eye Studies Open Access

Lot Slade; Kirk Bateman; Dale W Usner

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 952. doi:

A comparison of four warm compress devices Open Access

Graham Stetson; Christen Kenrick

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 953. doi:

Association Between Symptoms and Signs of Dry Eye after Allogeneic Hematopoietic Stem Cell Transplantation Open Access

Da Yeong Kim; Dae Yu kim; Hyun Seung Kim; Kyung-Sun Na

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 954. doi:

Altered Lymphotoxin alpha (LTA) level in tear fluid, measured with a POCT test, in dry eye patients

Open Access

Jing-Feng Huang; Xiang Lin; Zuguo Liu

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 955. doi:

Does diabetes make a difference in dry eye? Open Access

Scott Schwartz; Clare Halleran; Tracy Doll; Jennifer S Harthan; Matthew T Williams; Leslie E O'Dell; Natalie Bernabe; Milton M Hom

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 956. doi:

The Effect of 2% Rebamipide Eye drops on the Ocular Surface in Dry Eye Patients Open Access

Murat Dogru; Megumi Shinzawa; Seika Den; Hiroyuki Iseda; Mai Suzuki; Yoshiyuki Shibasaki; Jun Shimazaki

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 957. doi:

A hypothesis-free study of medication use and symptomatic dry eye in 79,866 participants Open Access

Laura Wolpert; Shehnaz Bazeer; Christopher J Hammond; Jelle Vehof

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 958. doi:

Dark rearing does not prevent prodromal rod oxidative stress in vivo in male Pde6b^rd10 mice Open Access

Bruce A Berkowitz; Robert Podolsky; Ali M Berri; Kristin Dernay; Fatema Shafie-Khorassani; Robin Roberts

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 959. doi:

The Joubert Syndrome cilia proteins arl13b, ahi1 and cc2d2a differentially modify the severity of retinal dysfunction due to loss of cep290 in zebrafish Open Access

Ping Song; Emma M Lessieur; Ellen Piccillo; Cabrielle C Nivar; Joseph Fogerty; Brian D Perkins

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 960. doi:

Evaluation of the safety of laser-delivered Photobiomodulation and its neuroprotection efficacy in a mouse model of Retinitis Pigmentosa Open Access

Jack Zi Jie Ao; Glyn Chidlow; John PM Wood; Robert J Casson

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 961. doi:

Onset of neuronal oscillation requires the loss of both rod and cone photoreceptors in deafferentated retinas Open Access

Ching-Kang Jason Chen; Takae Kiyama; Yu-Jiun Chen; Chai-An Mao

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 962. doi:

ARL2 regulates trafficking and expression of isoprenylated proteins and is crucial for development of photoreceptor outer segments Open Access

Houbin Zhang; Zhenglin Yang; Ting Lin; Yaqi Wu; Tongdan Zou; Jialiang yang; Yi Zhang

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 963. doi:

Pay attention to the toxicity of minocycline on photoreceptor cells Open Access

Yusheng Wang; Wenqin Xu

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 964. doi:

HIF1A is the responsible factor for cone degeneration and subretinal neovascularization in a mouse model of chronic hypoxia Open Access

Maya Barben; Christian Schori; Christian Grimm; Marijana Samardzija

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 965. doi:

Low-density RGR–bound membranes from suspension of outer segments Open Access

Zhaoxia Zhang; Henry KW Fong

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 966. doi:

Mitochondrial Dysfunction in Photoreceptors after Retinal Detachment
Open Access

Xueting Luo; Xiangjun She; Xinmin Lu; Xiaodong Sun

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 967. doi:

Cellular Response Following Bright Light Exposure in the Retina of Juvenile Rats Open Access

SHASHA LV; Anna Polosa; Pierre Lachapelle

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 968. doi:

Removal of the clock gene Bmal1 from 661W cells affects cell viability and response to oxidative stress Open Access

Kenkichi Baba; Ting-Chung Suen; Aida Sanchez-Bretano; Jason DeBruyne; P. Michael Iuvone; Gianluca Tosini

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 969. doi:

Validation and comparison of Achromatopsia mouse lines expressing a fluorescent marker in cone photoreceptors Open Access

Livia S Carvalho; Valentina Voigt; Iona Schuster; Paula Fuller-Carter; Juan Pablo Quesada; Sophia Vasiliou; David M Hunt

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 970. doi:

Lutein and zeaxanthin isomers ameliorate photoreceptor degeneration in Pde6^rd10 mice Open Access

Minzhong Yu; Craig Beight

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 971. doi:

Inner retinal remodelling in Tvrm4 rhodopsin mutant mice Open Access

Antonia Stefanov; Elena Novelli; Enrica Strettoi

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 972. doi:

Characterisation of Retinal Degeneration in Idh3a Mutant Mice Open Access

Amy Findlay; Klara Novakova; Lisa Mckie; Roderick Carter; Paul Potter; Ian Jackson

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 973. doi:

RNAseq Analysis to Understand the Cellular Mechanisms Involved in Thyroid
Hormone Signaling Suppression-induced Cone Protection Open Access

Hongwei Ma; Fan Yang; Willard M. Freeman; Xi-Qin Ding

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 974. doi:

The protective effect and immune suppressive mechanism of Fingomolid (FTY720) in light-induced retinal damage rats Open Access

Hui Chen; Qian Zhang

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 975. doi:

BDNF effects on retina derived 661W cells indicate distinct photoreceptor intracellular signalling pathways Open Access

Chitra Joseph; Vivek Kumar Gupta; Stuart L Graham

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 976. doi:

Photoreceptor Cholesterol Metabolism Regulates Age-Related Retinal Neurodegeneration Open Access

Norimitsu Ban; Abdoulaye Sene; Tae Jun Lee; Zhenyu Dong; Andrea Santeford; Jonathan Lin; Rajendra Apte

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 977. doi:

Effect of heat shock on mutant rhodopsin expression in a Xenopus laevis model of retinitis pigmentosa Open Access

Beatrice Tam; Damian Lee; Orson L Moritz

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 978. doi:

Deoxygedunin promotes TrkB receptor activation and downstream signalling cascades in photoreceptor cell line Open Access

Abubakar Siddiq Mangani; Chitra Joseph; Vivek Kumar Gupta; Stuart L Graham

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 979. doi:

Large-scale Whole-organism Phenotypic Screen Identifies Rod Cell Neuroprotectants Effective in Zebrafish and Mouse Models of Retinitis Pigmentosa Open Access

Liyun Zhang; Conan Chen; Jiang Qian; Hongkai Ji; Donald J Zack; Justin Hanes; David Ackerley; Baerbel Rohrer; Jeff S Mumm

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 980. doi:

CRISPR-Cas9-induced mutations in the mouse Rpgr (retinitis pigmentosa GTPase regulator) gene provide new insights into the role of the distinct RPGR isoforms in photoreceptor cilia Open Access

Wei Zhang; Linjing Li; Manisha Anand; Michael Brodsky; Hemant Khanna

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 981. doi:

Comparison of computerized system and human observers for vision assessment based on optomotor response in Rhodopsin knockout mice Open Access

Kin-Sang Cho; Jiaxin Xiao; Cong Shi; Karen Chang; Tor Paaske Utheim; Gang Luo; Dong Feng Chen

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 982. doi:

The co-receptor CD36 as a target in regulation of subretinal inflammation Open Access

Samy Omri; Katia Melal; Houda Tahiri; Dilan Mulumba; William Lubell; huy ong; Sylvain Chemtob

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 983. doi:

Establishment of a novel cone transfection technique for cone-rod dystrophy mouse models Open Access

Wataru Otsu; Jen-Zen Chuang; Ching-Hwa Sung

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 984. doi:

Modeling CRB1-associated LCA Using Patient-Specific Retinal Progenitor Cells Open Access

Lindsey Weed; Kamaljot Gill; Jean Bennett; Jason Mills

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 985. doi:

Lack of n3 VLC-PUFAs and Elovanoids correlates with impaired photoreceptor disk morphogenesis in AdipoR1 KO Open Access

William C Gordon; Nicolas G Bazan

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 986. doi:

Development of a Zebrafish Model of Retinitis Pigmentosa Open Access

Randy Igbinoba; Joshua Atkinson; Ya-Ping Lin; Gloria Orozco; Duc Nguyen; John O'Brien

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 987. doi:

Overexpression of the mitochondrial Ca²⁺ uniporter in cones alters Ca²⁺ and mitochondrial homeostasis Open Access

Rachel Hutto; Celia M Bisbach; James Hurley; Susan E Brockerhoff

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 988. doi:

Assessment of adjunctive gene therapy to dormant cones in end-stage retinitis pigmentosa Open Access

Mark Hassall; Michelle McClements; Alun R Barnard; Sher A Aslam; Robert E MacLaren

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 989. doi:

Retinal degeneration and subretinal Iba1⁺ accumulation in complement factor H-deficient mice are associated with increased gene expression of phagocytic markers Open Access

Natasha Buchanan; Erika Queiroz; John Demirs; Junzheng Yang; Barrett Leehy; Nalini Rangaswamy; Ivana Arellano; Maura Crowley; Chad E Bigelow; Karen Anderson; Sha-Mei Liao

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 990. doi:

Comparative transcriptomic and epigenomic analysis identifes regulators of neurogenic competence in retinal Müller glia. Open Access

Seth Blackshaw; Thanh Hoang; Jie Wang; Manuela Lahne; Levi Todd; Clayton Santiago; Nathalie Squires; Patrick Boyd; John D Ash; Andrew J Fischer; Jiang Qian; David R Hyde

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 991. doi:

Transcriptomics analysis of Muller glia in response to different damage paradigms in the adult zebrafish retina Open Access

David R Hyde; Patrick Boyd; Manuela Lahne; Thanh Hoang; Jie Wang; Clayton Santiago; Seth Blackshaw; Jiang Qian; John D Ash; Andy Fischer

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 992. doi:

Alpha-1-microglobulin attenuates oxidative stress and enhances photoreceptor survival in an in vitro model of rhegmatogenous retinal detachment Open Access

Linnea T Taylor; Hodan Abdshill; Jesper Bergwik; Bo Åkerström; Fredrik K Ghosh

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 993. doi:

Deletion of ER complex protein Emc3 led to photoreceptor degeneration Open Access

Xianjun Zhu; Lin Zhang

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 994. doi:

Reduced expression and delayed translocation of α-transducin in photoreceptors of a mouse model of Usher syndrome Open Access

Bhagwat V Alapure; Jennifer J Lentz

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 995. doi:

Benefitial effects of thioredoxin administration in experimental retinal degeneration Open Access

Maria Miranda; Roberto Gimeno-Hernández; Angel Fernández-Carbonell; Teresa Olivar; Vicente Hernández-Rabaza; Rosa Lopez-Pedrajas; Inmaculada Almansa

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 996. doi:

Stanniocalcin-2 preserves retinal function in a rat model of retinitis pigmentosa Open Access

Min Zhao; Wankun Xie; Shu-Huai Tsai; Maxwell G. Su; Travis W Hein; Lih Kuo; Robert H Rosa

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 997. doi:

New insights into the mechanisms of retinal degeneration due to Phosphodiesterase 6 (PDE6) deficiency

Open Access

Regine Lotte Muehlfriedel; Vithiyanjali Sothilingam; Marina Garcia Garrido; Naoyuki Tanimoto; Susanne Beck; Stylianos Michalakis; Martin Biel; Francois Paquet-Durand; Mathias W Seeliger

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 998. doi:

Protection of cone photoreceptors by CDNF (cerebral dopamine neurotrophic factor) Open Access

Yiwen Li; Jianmin Lu; Yihui Chen; Rong Wen

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 999. doi:

Disrupted electroretinogram responses in RPE or photoreceptor Adiponectin receptor 1 (AdipoR1) conditional KOs Open Access

Blake Matherne; Marie-Audrey Ines Kautzmann; William C Gordon; Nicolas G Bazan

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 1000. doi:

Dark-rearing reduces degeneration and alters the characteristics of cGMP dysregulation in rd10 mice Open Access

Hope Titus; Kyle K. Weller; Jenny Li; Richard G Weleber; Mark E Pennesi; Paul Yang

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 1001. doi:

Wedelolactone protects DNA-induced photoreceptor death

Open Access

Kevin Harkin; Sofia Pavlou; Alan W Stitt; Heping Xu; Mei Chen

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 1002. doi:

Selectively knocking down hexokinase 2 in rods leads to retinal degeneration Open Access

Rui Zhang; Weiyong Shen; So-Ra Lee; Michelle X. Yam; Ling Zhu; Ashish Easow Mathai; Ching-Kang Jason Chen; Mark C Gillies

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 1003. doi:

A frameshift mutation in RDH12 causes autosomal dominant retinitis pigmentosa in families of Tunisian Jewish origin Open Access

Boris Rosin; Prasanthi Namburi; Muhammad Imran Khan; Frans P Cremers; Eyal Banin; Dror Sharon

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 1004. doi:

Long-term Rescue of Photoreceptors in a Rodent Model of Retinitis Pigmentosa Associated with MERTK Gene Mutation Open Access

Daniel V Palanker; Seungbum Kang; Roopa Dalal; Yi Quan; Henri Lorach

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 1005. doi:

Low LED light exposure as a model of retinal degeneration in Albino rats. Open Access

Maria Mercedes Benedetto; Mario Eduardo Guido; Maria Ana Contin

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 1006. doi:

Retinal bipolar cell gene changes in the rd1 model of inherited retinal degeneration Open Access

Michael James Gilhooley; Doron G Hickey; Steven Hughes; Mark W Hankins

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 1007. doi:

Stanniocalcin-1 rescues photoreceptor degeneration in a porcine model of retinitis pigmentosa Open Access

Wankun Xie; Min Zhao; Shu-Huai Tsai; Maxwell G. Su; Gavin W Roddy; Patrick D. Bradley; Matthew M LaVail; Travis W Hein; Lih Kuo; Robert H Rosa

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 1008. doi:

Single cell RNA-Seq to elucidate the mechanism of delayed cell death in retinal dystrophy. Open Access

Rachayata Dharmat; Sangbae Kim; Yumei Li; Aiden Eblimit; Rui Chen

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 1009. doi:

Short periods of dark adaptation in a light-induced damage model of AMD produces retinal degeneration in pigmented zebrafish Open Access

Amanda Khan; Salvatore L Stella

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 1010. doi:

There and Back Again: Transient Microglial Responses to Localized Neuronal Damage In Vivo Open Access

Eric B Miller; Pengfei Zhang; Mayank Goswami; Robert J Zawadzki; Edward N. Pugh; Marie E. Burns

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 1011. doi:

Unraveling Sphingolipid Signaling in the Retina, one gene at a time- the role of Sphingosine kinase 2 Open Access

Nawajes A Mandal; Hui Qi; Joseph Wilkerson; megan stiles; sufiya khanam; Lynda Wilmott; Soma Dutta; Jerome Cole

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 1012. doi:

Variability in therapeutic outcome due to age of P23H rhodopsin mice at time of dosing can be reduced by enhanced retinal drug delivery. Open Access

Anna-Sophia Kiang; Paul Kenna; Marian M Humphries; Anh Nguyen; James Keaney; Jane G Farrar; Matthew Campbell; Peter Humphries

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 1013. doi:

Early steps of photoreceptor degeneration in a Xenoups laevis model of retinitis pigmentosa Open Access

Ulisse Bocchero; Monica Mazzolini; Beatrice M. Tam; Colette Chiu; Vincent Torre; Orson L Moritz

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 1014. doi:

Quercetin prevented retinal degeneration induced by Sodium iodate
Open Access

Byul-Nim Ahn; Yerin Shin; Si-Kyung Kim; JaeWook Yang

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 1015. doi:

Evidence of oculomotor dominance during smooth pursuit in depth Open Access

Arvind Chandna; Stephen J Heinen; Jeremy Badler; Watamaniuk N J Scott

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 1016. doi:

Cyclofusion ranges in a healthy adult population Open Access

Sara M Flodin; Tony Pansell; Agneta Rydberg; Marita Andersson Gronlund

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 1017. doi:

Motor adaptation of reflexive fusional vergence is impaired in Convergence Insufficiency
Open Access

William R Bobier; Ian Erkelens

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 1018. doi:

Change of Perceived Size of Object by Convergence or Divergence without Accommodation Measured by Three-Dimensional Scenography Open Access

Ichiro Hamasaki; kiyo shibata; Takehiro Shimizu; Satoshi Hasebe; Hiroshi Ohtsuki; Fumio Shiraga

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 1019. doi:

Decreased binocular summation ratio in intermittent exotropia. Open Access

JEONGMIN KWON; JAEHO JUNG

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 1020. doi:

Properties of cells associated with strabismus angle in the rostral superior colliculus of strabismic monkey Open Access

Suraj Upadhyaya; Vallabh Das

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 1021. doi:

Clinical comparison of tenacious proximal fusion and high AC/A ratio types of intermittent exotropia Open Access

Soo Jung Lee; Hae Rang Kim; JUNWOO PARK; Jung Min Park

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 1022. doi:

The analysis of ocular deviations between dominant and non-dominant eye using video-oculography (VOG) in intermittent exotropia Open Access

Sung-Hyuk Moon; Jihoon Ban; IlHan Yun; JaeWook Yang

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 1023. doi:

An objective rapid system based on eye tracking for eye deviation measurement in children and adults Open Access

Oren Yehezkel; Abraham Spierer; Ran Yam; Dan Oz; Michael Belkin; Tamara Wygnanski – Jaffe

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 1024. doi:

Change in the eye position under general anesthesia: Is it related to the etiology in intermittent exotropia? Open Access

Eun Hye Jung; Sang In Khwarg; Young Suk Yu; Seong-Joon Kim

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 1025. doi:

A Reevaluation of Prism Position in the Measurement of Strabismus Open Access

Declan Kirk; Coby Ray; Kenn Freedman

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 1026. doi:

Amblyopia as a risk factor for recurrence in patients with infantile esotropia treated surgically: 10-year follow-up. Open Access

Ruben Espino Icazbalceta; Mariana Urdapilleta; Alejandro Zermeno; Jessica Vargas; Claudia Murillo

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 1027. doi:

Extraocular Muscles Insertion Analysis Using Ultrasound Biomicroscopy and Anterior Segment Optical Coherence Tomography and Intraoperative Correlation in Adult Patients with Strabismus Af... Open Access

Astrid Enid Gonzalez Ramos; Natalia Cintron; Marino Blasini Torres; Rene Vazquez Botet

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 1028. doi:

Anterior segment coherence tomography to assess the insertion of extraocular muscles in patients previously submitted to strabismus surgery Open Access

Taciana Toda; Caroline Yukie Hashimoto; Eduardo Toshio Sato; Ronaldos Boaventura Barcello

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 1029. doi:

Analysis of GPR143 Gene Mutations in Five Chinese Families with the Ocular Albinism Type I Open Access

Ningdong Li; jingjing jiang

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 1030. doi:

Objective Evaluation of Characteristics of Visual Fatigue in Patients with Intermittent Exotropia
Open Access

Masakazu Hirota; Takeshi Morimoto; Hiroyuki Kanda; Takao Endo; Tomomitsu Miyoshi; Suguru Miyagawa; Yoko Hirohara; Tatsuo Yamaguchi; Makoto Saika; Takashi Fujikado

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 1031. doi:

The Effect of Strabismus Surgery on Self-Esteem Open Access

Kimberly Estes; Rebecca Parrish; James Sinacore; Patricia Mumby; James F McDonnell

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 1032. doi:

Is Myopia Associated with the Incidence and Progression of Diabetic Retinopathy? Open Access

Ryan Man; Alfred TL Gan; Preeti Gupta; Eva Fenwick; Charumathi Sabanayagam; Nicholas Tan; Tien Yin Wong; Ching-Yu Cheng; Ecosse Luc Lamoureux

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 1033. doi:

Diabetes mellitus in MacTel
Can Diabetes Mellitus be a negative prognosticator in MacTel? Open Access

Daniela Florea; Tatiana Mansour; Traci Clemons; Konstantinos Balaskas; Catherine Egan; Tunde Peto

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 1034. doi:

Risk Factors and Clinical Characteristics for Retinal Neurodegeneration in Type 2 Diabetes Open Access

Jae Min Kim; Kiyoung Kim; Sung Rae Noh; Eung-Suk Kim; Sang Youl Rhee; Suk Chon; Jeong-taek Woo; Seung-Young Yu

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 1035. doi:

Risk Factors for Central Serous Retinopathy Open Access

Maggie Zhou; Sophie Bakri; Suzann Pershing

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 1036. doi:

Risk factors associated with complex vitreoretinal surgery for patients with diabetes. Open Access

Kristen Nwanyanwu; Joshua Warren

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 1037. doi:

The prevalence of diabetes mellitus and diabetic retinopathy in the Rio Grande Valley: A demographics report Open Access

Donald C C Meadows; Hamzah Khalaf; Matthew P Johnson; Victor H Gonzalez

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 1039. doi:

Association of retinal vessel diameters and diabetic retinopathy in pregnancy Open Access

Barbara E K Klein; Kristine E Lee; Stacy M Meuer; Anne Mosher; Andy Ewen; Ronald Klein

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 1040. doi:

Is Diabetic Retinopathy Severity an Independent Risk Factor for Stroke in the Framingham Heart Study Cohort? Open Access

Catherine Qiuzi Zhu; Sudha Seshadri; Jayandra Jung Himali; Alexa Beiser; Howard S Ying

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 1041. doi:

Red flags of diabetic retinopathy (DR) in patients with Type 1 Diabetes mellitus (T1DM) using HbA1c level and antihypertensive medication Open Access

Lydia Marahrens; Fritsche Andreas; Daniel Roeck; Focke Ziemssen

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 1042. doi:

Diabetic Retinopathy Status as a Marker for More Severe Reduction in Circulating Endothelial Progentior Cells and Systemic Atherosclerosis in Diabetics
Open Access

Kendrick Co Shih; Ian Wong; Jimmy SM Lai; Kai Hang Yiu

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 1043. doi:

Comparing Teleretinal Screening-Identified Diabetic Retinopathy with Diabetic Nephropathy and Other Markers of Systemic Disease Open Access

Sean Michael Rodriguez; Eric B. Hamill; Nabeel Moon; Amritha Kanakamedala; Christina Y. Weng

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 1044. doi:

Barriers to and facilitators of diabetic retinopathy screening in a high-risk population. Open Access

Elizabeth Fairless; Kristen Nwanyanwu

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 1045. doi:

Ecological factors influencing patient adherence with diabetic eye screening in rural communities: a qualitative study Open Access

Nicholas Zupan; Olayinka Shiyanbola; Rebecca Swearingen; Julia Carlson; Nora Jacobson; Maureen Smith; Jane Mahoney; Ronald Klein; Timothy Bjelland; Yao Liu

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 1046. doi:

Geographical Nationwide Mapping of Diabetic Retinopathy Using Teleretinal Screening Open Access

Robert Wong; Gopal Karsaliya; Shelley Day Ghafoori; Jose A Martinez; Peter A Nixon; Clio A Harper; Mark Levitan; Ryan C Young

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 1048. doi:

Evaluation of a diabetic retinopathy telemedicine screening program in a metropolitan primary care setting Open Access

Miel Sundararajan; Ronald Gentile; Sophia Saleem; Meenakashi Gupta

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 1049. doi:

Assessing diabetic eye screening rates in a rural, multi-payer health system Open Access

Julia Carlson; Stephany Georgeson; Rebecca Swearingen; Nicholas Zupan; Maureen Smith; Jane Mahoney; Ronald Klein; Timothy Bjelland; Yao Liu

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 1050. doi:

Impact of Appointment Compliance on Visual Outcomes in Patients with Diabetic Retinopathy Open Access

Daniel Rahul Agarwal; Belinda Udeh; Brittany Lapin; Jack Campbell; Aleksandra V. Rachitskaya

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 1051. doi:

Evaluation of Compliance Rates in Patients with Diabetic Retinopathy Open Access

Suruchi Bhardwaj; Rachel Anderson; Bing Chiu; David Eppenstein; Kenneth J Wald; Joseph J Tseng; Yasha Modi

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 1052. doi:

Systematic Review of Photographic Screening Methods in Diabetic Retinopathy Open Access

William Yan; Myra McGuinness; Rahul Chakrabarti; Kathy Fotis; Mingguang He; Robert Patrick Finger

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 1054. doi:

Validating Optos® ultra wide-field imaging against conventional Topcon® imaging Open Access

Stine Byberg; Dorte Visitisen; Morten Haaning Charles; Marianne Valerius; Ellen Juul; Marit Eika Jørgensen; Henrik Lund-Andersen

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 1055. doi:

Diabetic Capillary Nonperfusion in the Macula and Extramacular areas on Optical Coherence Tomography Angiography Open Access

shota yasukura; Tomoaki Murakami; Kiyoshi Suzuma; Tatsuya Yoshitake; Masahiro Fujimoto; Hideo Nakanishi; Maho Oishi; Akitaka Tsujikawa

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 1056. doi:

Survey of TREATment for Diabetic Macular Edema (STREAT-DME) Study: Results by year from real world data in Japan Open Access

TAKUYA UTSUMI; Masahiko Shimura; Shigehiko Kitano; Taiji Sakamoto

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 1057. doi:

DIABETIC RETINOPATHY IN RURAL POPULATION, EXPERIENCE IN A MEXICAN INSTITUTION OF OPHTHALMOLOGY Open Access

Veronica Adriana Romero Morales; MIGUEL ANGEL VAZQUEZ; RENATA GARCIA FRANCO; ELISA HERNANDEZ; Ximena Mira; Diana dorantes; Thalia Gonzalez; Jose Antonio López; Valeria Millán; Miguel Kristo Miranda Santiago; Dalyir Rodriguez; Luis Alberto Romano; Diana Laura Torres; Paulina Ramirez; Gabriela Hernandez Alba; Van C Lansingh

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 1058. doi:

Retinal Panfotocoagulation: Outcome of diabetic patients in an Ophthalmological Hospital inserted in the Brazilian public health system: Goiânia, Goiás: Brazil Open Access

Eduardo Ribeiro Coutinho Dalia; Kenard Neto; Renata Faro; Lorena Pedroso; Thiago Martins; Leonardo Pinheiro Teixeira; Tiago Rassi

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 1059. doi:

Follow-up patterns among patients with treatment-naïve proliferative diabetic retinopathy offered panretinal photocoagulation Open Access

Sophie Cai; Mira Sachdeva; Neil M Bressler

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 1060. doi:

Visual Acuity Improvement by Refraction of Low Vision Patients in an Academic Medical Center Open Access

Xinxing Guo; Bonnielin K Swenor; Judith Goldstein

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 1061. doi:

Baseline traits of patients presenting for low vision services in a community health center Open Access

Alexis G Malkin; Robert W Massof

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 1062. doi:

Regional Differences in Eye Health: Findings from Mwanza, Tanzania Open Access

Sahil Aggarwal; David Ju; Mitul C. Mehta

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 1063. doi:

Investigation of Visual Disability in Previous Zhabei District, Shanghai, 2010 - 2017 Open Access

JILI CHEN; Ce zheng

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 1064. doi:

Clinico-epidemiologic features of oculocutaneous albinism in Mexico City Open Access

Carlos Muller Morales; Juan Carlos Zenteno; Ana María Beauregard

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 1065. doi:

Quality of life of patients attending a low-vision rehabilitation service in Brazil Open Access

Matheus Bedendo Rodrigues Silva; Gabriela Coutinho Cavalieri; Lorenna Souza Cota; Elouise Zwirtes Frare; Erika Hoyama; Tiemi Matsuo; Nobuaqui Hasegawa

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 1066. doi:

Contextual Factors that affect Participation of Adults with Deafblindness in Indian Society: A Qualitative Study Open Access

Atul Jaiswal; Heather Aldersey; Walter Wittich; Mansha Mirza; Marcia Finlayson

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 1067. doi:

Prevalence and severity of dual sensory loss (vision & hearing) in the Canadian Longitudinal Study on Aging Open Access

Walter Wittich; Anni Hämäläinen; Margaret Kathy Pichora-Fuller; Natalie Phillips; Lebo Kolisang; Dawn Guthrie; Paul Mick

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 1068. doi:

Prevalence of Visual Impairment in the Municipality of Braga -Portugal using capture-recapture methods Open Access

Pedro Lima Ramos; Rui Santana; Inês Sousa; Amandio A Rocha-Sousa; Antonio Filipe Macedo

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 1069. doi:

Exploring barriers to physical activity faced by people with vision loss Open Access

Antonio Filipe Macedo; Diana Santos; Laura Hernández_Moreno; Marta Leitao; Keziah Latham; Joao Linhares

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 1070. doi:

Relationship between low vision rehabilitation outcomes and goals included in the plan of care Open Access

Kyoko Fujiwara; Theresa M Smith; Robert W Massof

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 1071. doi:

Feasibility of developing a single disease severity scale for Retinitis Pigmentosa Open Access

Rob Chun; Gislin Dagnelie; Robert W Massof

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 1072. doi:

A novel Bayesian approach to testing and analyzing visual acuity Open Access

Luis A Lesmes

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 1073. doi:

Psychophysical validation of a novel Bayesian method for measuring visual acuity Open Access

Yukai Zhao; Luis A Lesmes; Michael Dorr; Peter J. Bex; Zhong-Lin Lu

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 1074. doi:

A Bayesian method using through focus visual acuity to predict rates of spectacle wear for pseudophakic patients Open Access

Robert Rosen; Linda Tsai; Aixa Alarcon; Kendra Hileman; Patricia Piers

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 1075. doi:

Feedback improves measured visual acuity in adults Open Access

Andrew V Collins; Muthana Noori; Robert J Jacobs; Nicola S Anstice

Investigative Ophthalmology & Visual Science July 2018, Vol.59, 1076. doi:

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