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Special Issue

Dry Eye Research Update in Japan in Celebration of the 25th Anniversary of the Dry Eye Society and the 10th Anniversary of Hakone Dry Eye Club Open Access
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Kazuo Tsubota
Tags: dry eye syndromes, societies
Investigative Ophthalmology & Visual Science November 2018, Vol.59, DESi-DESii. doi:https://doi.org/10.1167/iovs.18-24625
What We Know About the Epidemiology of Dry Eye Disease in Japan Open Access
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Miki Uchino
Tags: dry eye syndromes, epidemiology, prevalence, signs and symptoms, risk factors
Investigative Ophthalmology & Visual Science November 2018, Vol.59, DES1-DES6. doi:https://doi.org/10.1167/iovs.17-23491
Definition and Diagnostic Criteria of Dry Eye Disease: Historical Overview and Future Directions Open Access
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Jun Shimazaki
Tags: dry eye syndromes, signs and symptoms
Investigative Ophthalmology & Visual Science November 2018, Vol.59, DES7-DES12. doi:https://doi.org/10.1167/iovs.17-23475
Tear Film–Oriented Diagnosis and Tear Film–Oriented Therapy for Dry Eye Based on Tear Film Dynamics Open Access
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Norihiko Yokoi; Georgi As Georgiev
Tags: dry eye syndromes, eye, tear film finding, fluorescein, eyedrops
Investigative Ophthalmology & Visual Science November 2018, Vol.59, DES13-DES22. doi:https://doi.org/10.1167/iovs.17-23700
Assessment of Dry Eye Symptoms: Current Trends and Issues of Dry Eye Questionnaires in Japan Open Access
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Atsushi Shiraishi; Yuri Sakane
Tags: dry eye syndromes, questionnaires, signs and symptoms, trend
Investigative Ophthalmology & Visual Science November 2018, Vol.59, DES23-DES28. doi:https://doi.org/10.1167/iovs.18-24570
Functional Visual Acuity Open Access
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Minako Kaido
Tags: system of measurement, vision, visual acuity, cataract, glaucoma
Investigative Ophthalmology & Visual Science November 2018, Vol.59, DES29-DES35. doi:https://doi.org/10.1167/iovs.17-23721
Irregular Astigmatism and Higher-Order Aberrations in Eyes With Dry Eye Disease Open Access
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Shizuka Koh
Tags: astigmatism, dry eye syndromes, eye, optics, cornea
Investigative Ophthalmology & Visual Science November 2018, Vol.59, DES36-DES40. doi:https://doi.org/10.1167/iovs.17-23500
Application of In Vivo Confocal Microscopy in Dry Eye Disease Open Access
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Yukihiro Matsumoto; Osama M. A. Ibrahim
Tags: cornea, dry eye syndromes, microscopy, confocal, inflammatory cells, neurons
Investigative Ophthalmology & Visual Science November 2018, Vol.59, DES41-DES47. doi:https://doi.org/10.1167/iovs.17-23602
Meibography: A Japanese Perspective Open Access
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Reiko Arita
Tags: japanese, meibomian gland, pathophysiology, lipids, eyelid
Investigative Ophthalmology & Visual Science November 2018, Vol.59, DES48-DES55. doi:https://doi.org/10.1167/iovs.17-23631
Relationship Between Eyelid Pressure and Ocular Surface Disorders in Patients With Healthy and Dry Eyes Open Access
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Masahiko Yamaguchi; Atsushi Shiraishi
Tags: dry eye syndromes, eyelid, eye
Investigative Ophthalmology & Visual Science November 2018, Vol.59, DES56-DES63. doi:https://doi.org/10.1167/iovs.17-23586
Short Tear Film Breakup Time–Type Dry Eye Open Access
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Kazuo Tsubota
Tags: dry eye syndromes, tear film finding
Investigative Ophthalmology & Visual Science November 2018, Vol.59, DES64-DES70. doi:https://doi.org/10.1167/iovs.17-23746
Sjögren's Syndrome, Non-Sjögren's Syndrome, and Graft-Versus-Host Disease Related Dry Eye Open Access
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Yoko Ogawa
Tags: dry eye syndromes, graft-versus-host disease, sjogren's syndrome, syndrome
Investigative Ophthalmology & Visual Science November 2018, Vol.59, DES71-DES79. doi:https://doi.org/10.1167/iovs.17-23750
Severe Dry Eye With Combined Mechanisms is Involved in the Ocular Sequelae of SJS/TEN at the Chronic Stage Open Access
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Chie Sotozono; Mayumi Ueta; Norihiko Yokoi
Tags: dry eye syndromes, stevens-johnson syndrome, signs and symptoms
Investigative Ophthalmology & Visual Science November 2018, Vol.59, DES80-DES86. doi:https://doi.org/10.1167/iovs.18-24019
Meibomian Gland Dysfunction: Recent Progress Worldwide and in Japan Open Access
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Shiro Amano
Tags: meibomian gland, pathophysiology
Investigative Ophthalmology & Visual Science November 2018, Vol.59, DES87-DES93. doi:https://doi.org/10.1167/iovs.17-23553
Inflamed Obstructive Meibomian Gland Dysfunction Causes Ocular Surface Inflammation Open Access
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Tomo Suzuki
Tags: inflammation, meibomian gland, pathophysiology
Investigative Ophthalmology & Visual Science November 2018, Vol.59, DES94-DES101. doi:https://doi.org/10.1167/iovs.17-23345
Contact Lens-Associated Dry Eye Disease: Recent Advances Worldwide and in Japan Open Access
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Takashi Kojima
Tags: contact lenses, dry eye syndromes, lens (device), lens, crystalline, tear film finding
Investigative Ophthalmology & Visual Science November 2018, Vol.59, DES102-DES108. doi:https://doi.org/10.1167/iovs.17-23685
Dry Eye After LASIK Open Access
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Ikuko Toda
Tags: dry eye syndromes, keratomileusis, laser in situ, signs and symptoms
Investigative Ophthalmology & Visual Science November 2018, Vol.59, DES109-DES115. doi:https://doi.org/10.1167/iovs.17-23538
Medical Treatment for Dry Eye in Japan Open Access
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Hitoshi Watanabe
Tags: dry eye syndromes, rebamipide, medical management
Investigative Ophthalmology & Visual Science November 2018, Vol.59, DES116-DES120. doi:https://doi.org/10.1167/iovs.18-24130
Autologous Serum and Serum Components Open Access
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Akihiro Higuchi
Tags: dry eye syndromes, eyedrops
Investigative Ophthalmology & Visual Science November 2018, Vol.59, DES121-DES129. doi:https://doi.org/10.1167/iovs.17-23760
Approach to Dry Eye in Video Display Terminal Workers (Basic Science) Open Access
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Shigeru Nakamura
Tags: dry eye syndromes, video display terminals
Investigative Ophthalmology & Visual Science November 2018, Vol.59, DES130-DES137. doi:https://doi.org/10.1167/iovs.17-23762
Systemic Health and Dry Eye Open Access
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Motoko Kawashima
Tags: dry eye syndromes, health
Investigative Ophthalmology & Visual Science November 2018, Vol.59, DES138-DES142. doi:https://doi.org/10.1167/iovs.17-23765
Sleep Disorders are a Prevalent and Serious Comorbidity in Dry Eye Open Access
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Masahiko Ayaki; Kazuo Tsubota; Motoko Kawashima; Taishiro Kishimoto; Masaru Mimura; Kazuno Negishi
Tags: sleep disorders, dry eye syndromes, sleep
Investigative Ophthalmology & Visual Science November 2018, Vol.59, DES143-DES150. doi:https://doi.org/10.1167/iovs.17-23467
Secreted Mucins on the Ocular Surface Open Access
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Yuichi Hori
Tags: mucins, dry eye syndromes, goblet cells, conjunctiva
Investigative Ophthalmology & Visual Science November 2018, Vol.59, DES151-DES156. doi:https://doi.org/10.1167/iovs.17-23623
The Ocular Surface Glycocalyx and its Alteration in Dry Eye Disease: A Review Open Access
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Yuichi Uchino
Tags: dry eye syndromes, glycocalyx, mucins, galectin 3
Investigative Ophthalmology & Visual Science November 2018, Vol.59, DES157-DES162. doi:https://doi.org/10.1167/iovs.17-23756
Potential Role of Oxidative Stress in Ocular Surface Inflammation and Dry Eye Disease Open Access
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Murat Dogru; Takashi Kojima; Cem Simsek; Kazuo Tsubota
Tags: dry eye syndromes, inflammation, oxidative stress
Investigative Ophthalmology & Visual Science November 2018, Vol.59, DES163-DES168. doi:https://doi.org/10.1167/iovs.17-23402
Regeneration of Lacrimal Gland Function to Maintain the Health of the Ocular Surface Open Access
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Tetsuya Kawakita
Tags: animal model, health, inflammation, langer-giedion syndrome, mice
Investigative Ophthalmology & Visual Science November 2018, Vol.59, DES169-DES173. doi:https://doi.org/10.1167/iovs.17-23576
Advances in Functional Restoration of the Lacrimal Glands Open Access
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Masatoshi Hirayama
Tags: lacrimal gland, stem cells, epithelium, body tissue, injection therapy
Investigative Ophthalmology & Visual Science November 2018, Vol.59, DES174-DES182. doi:https://doi.org/10.1167/iovs.17-23528
Results of Detailed Investigations Into Stevens-Johnson Syndrome With Severe Ocular Complications Open Access
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Mayumi Ueta
Tags: cold medication, disease susceptibility, genes, hla-a antigens, hla-a2 antigen
Investigative Ophthalmology & Visual Science November 2018, Vol.59, DES183-DES191. doi:https://doi.org/10.1167/iovs.17-23537
Inflammatory Response in Dry Eye Open Access
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Takefumi Yamaguchi
Tags: dry eye syndromes, inflammation, inflammatory response
Investigative Ophthalmology & Visual Science November 2018, Vol.59, DES192-DES199. doi:https://doi.org/10.1167/iovs.17-23651
Copyright © 2025 Association for Research in Vision and Ophthalmology.
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