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Anatomy and Pathology/Oncology

The Association Between Retinopathy of Prematurity and Ocular Growth Open Access
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Dimitrios Kardaras; Eleni Papageorgiou; Katerina Gaitana; Ioanna Grivea; Vasileios A. Dimitriou; Sofia Androudi; Antonios Gounaris; Evangelia E. Tsironi
Tags: infant, retinopathy of prematurity, body weight, eye, risk factors
Investigative Ophthalmology & Visual Science January 2019, Vol.60, 98-106. doi:10.1167/iovs.18-24776
Oral Selumetinib Does Not Negatively Impact Photoreceptor Survival in Murine Experimental Retinal Detachment Open Access
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Colleen M. Cebulla; Bongsu Kim; Valerie George; Tyler Heisler-Taylor; Sumaya Hamadmad; Alana Y. Reese; Shaili S. Kothari; Rania Kusibati; Hailey Wilson; Mohamed H. Abdel-Rahman
Investigative Ophthalmology & Visual Science January 2019, Vol.60, 349-357. doi:10.1167/iovs.18-25405

Biochemistry and Molecular Biology

Critical Role of mTORC2-Akt Signaling in TGF-β1-Induced Myofibroblast Differentiation of Human Pterygium Fibroblasts Open Access
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Sun Woong Kim; Hye-In Kim; Bikash Thapa; Selikem Nuwromegbe; Keunwook Lee
Tags: fibroblasts, mechanistic target of rapamycin complex 2, mtor serine-threonine kinases, proto-oncogene proteins c-akt, pterygium
Investigative Ophthalmology & Visual Science January 2019, Vol.60, 82-92. doi:10.1167/iovs.18-25376
Bidirectional Analysis of Cryba4-Crybb1 Nascent Transcription and Nuclear Accumulation of Crybb3 mRNAs in Lens Fibers Open Access
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Saima Limi; Yilin Zhao; Peng Guo; Melissa Lopez-Jones; Deyou Zheng; Robert H. Singer; Arthur I. Skoultchi; Ales Cvekl
Tags: crystallins, genes, lens (device), lens, crystalline, rna, messenger
Investigative Ophthalmology & Visual Science January 2019, Vol.60, 234-244. doi:10.1167/iovs.18-25921
Cytokine Profiling in Patients With Exudative Age-Related Macular Degeneration and Polypoidal Choroidal Vasculopathy Open Access
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Rupesh Agrawal; Praveen Kumar Balne; Xin Wei; Veonice Au Bijin; Bernett Lee; Arkasubhra Ghosh; Raja Narayanan; Mukesh Agrawal; John Connolly
Investigative Ophthalmology & Visual Science January 2019, Vol.60, 376-382. doi:10.1167/iovs.18-24387

Clinical and Epidemiologic Research

Preschool Children Exhibit Evident Compensatory Role of Internal Astigmatism in Distribution of Astigmatism: The Nanjing Eye Study Open Access
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Zijin Wang; Dan Huang; Xuejuan Chen; Hui Zhu; Qigang Sun; Yue Wang; Xiaohan Zhang; Yue Wang; Leili Zhai; Chenyang Wang; Hu Liu
Tags: astigmatism, eye, preschool child
Investigative Ophthalmology & Visual Science January 2019, Vol.60, 73-81. doi:10.1167/iovs.18-24799
Randomized, Controlled, Double-Masked, Multicenter, Pilot Study Evaluating Safety and Efficacy of Intranasal Neurostimulation for Dry Eye Disease Open Access
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Geoffrey S. Cohn; Dean Corbett; Abi Tenen; Minas Coroneo; James McAlister; Jennifer P. Craig; Trevor Gray; David Kent; Neil Murray; Con Petsoglou; Stephanie N. Baba; Edward J. Holland
Tags: dry eye syndromes, pilot projects, safety, tear production
Investigative Ophthalmology & Visual Science January 2019, Vol.60, 147-153. doi:10.1167/iovs.18-23984
Longitudinal Changes in Spherical Equivalent Refractive Error Among Children With Preschool Myopia Open Access
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Yin Hu; Xiaohu Ding; Wen Long; Mingguang He; Xiao Yang
Tags: child, myopia, preschools, refraction, refractive errors
Investigative Ophthalmology & Visual Science January 2019, Vol.60, 154-160. doi:10.1167/iovs.18-24862

Cornea

MiR-34c Participates in Diabetic Corneal Neuropathy Via Regulation of Autophagy Open Access
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Jianzhang Hu; XinYing Hu; Tong Kan
Tags: autophagy, cornea, diabetes mellitus, neurons, neuropathy
Investigative Ophthalmology & Visual Science January 2019, Vol.60, 16-25. doi:10.1167/iovs.18-24968
Noninvasive Assessment of Corneal Crosslinking With Phase-Decorrelation Optical Coherence Tomography Open Access
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Brecken J. Blackburn; Shi Gu; Matthew R. Ford; Vinícius de Stefano; Michael W. Jenkins; William J. Dupps, Jr; Andrew M. Rollins
Tags: cornea, corneal collagen cross-linking, diagnostic imaging, eye, motion
Investigative Ophthalmology & Visual Science January 2019, Vol.60, 41-51. doi:10.1167/iovs.18-25535
Wnt Signaling Is Required for the Maintenance of Human Limbal Stem/Progenitor Cells In Vitro Open Access
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Sheyla González; Denise Oh; Elfren R. Baclagon; Jie J. Zheng; Sophie X. Deng