Volume 60 Issue 9 | IOVS

Subretinal visual implant. Where are we today and where are we going to? Open Access

Katarina Stingl

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 1. doi:

Photovoltaic restoration of sight in age-related macular degeneration Open Access

Daniel V Palanker

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 2. doi:

Human stem-cell-derived photoreceptors for cell-based therapies Open Access

Volker Busskamp

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 3. doi:

Gene delivery to the primate retina Open Access

Leah Byrne

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 4. doi:

Optogenetic approaches to restoring vision Open Access

Zhuo-Hua Pan

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 5. doi:

Optogenetic restoration of vision in the macaque Open Access

William H Merigan

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 6. doi:

Alzheimer's disease manifestation in the retina: early biomarkers and retinal imaging in patients Open Access

Maya Koronyo-Hamaoui

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 7. doi:

The retina as a biomarker of Parkinson disease Open Access

Nicolas Cuenca

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 8. doi:

Ocular manifestations of traumatic brain injury Open Access

José E. Capo-Aponte

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 9. doi:

Ocular and systemic presentations of phosphoinositide signaling defects Open Access

Yang Sun

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 10. doi:

Ocular side effects of systemic chemotherapy: management strategies and mechanistic clues Open Access

Colleen M Cebulla

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 11. doi:

An overview of Big Data: Promises and potential pitfalls Open Access

Laura B. Balzer

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 12. doi:

Integrating Big Data into Ophthalmology Open Access

Michael F Chiang

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 13. doi:

Big Data Sets: Leveraging existing data sources for Big Data analyses in ophthalmology Open Access

Joshua D Stein

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 14. doi:

Big Data -Omics: Approaches for Genetics and Biological Research Open Access

Christopher J Hammond

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 15. doi:

Implications of Big Data: Potential impacts on research, patient care, and policy Open Access

Anne L Coleman

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 16. doi:

Adenosine triphosphate (ATP) induces constriction after intravascular and dilatation after extravascular administration on porcine retinal arterioles ex vivo Open Access

Charlotte Ernst; Peter Skov Jensen; Christian Aalkjaer; Toke Bek

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 17. doi:

Ocular biodistribution and duration of action of low-dose LNA oligonucleotides Open Access

Sindri Traustason; Ruben Alvarez Sanchez; Uwe Wessels; Jean-Luc Mary; Elke-Astrid Atzpodien; Jürgen Funk; Heidi Hudlebusch; Susanne Kammler

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 18. doi:

Age-related decline of retinal oxygen extraction in healthy subjects Open Access

Gerhard Garhofer; Ahmed Bata; Stephan Szegedi; Gerold C Aschinger; Doreen Schmidl; Jacqueline Chua; René M Werkmeister; Leopold Schmetterer

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 19. doi:

Modulation of the electrical activity in degenerative retinas of rd10 mice using neuroprotective drugs Open Access

Kim Schaffrath; Sabine Diarra; Jana Gehlen; Frank Muller; Peter Walter; Sandra Johnen

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 20. doi:

Retinal oxygen metabolism is altered in patients with mild cognitive impairment and Alzheimer’s disease Open Access

Stephan Szegedi; Peter Dal-Bianco; Elisabeth Stögmann; Tatjana Traub-Weidinger; Michael Rainer; Andreas Masching; Doreen Schmidl; René M Werkmeister; Leopold Schmetterer; Gerhard Garhofer

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 21. doi:

Role of hypoxia-inducible factor-1α (HIF-1α) in retinal ganglion cell (RGC) death in glaucoma. Open Access

Sudha Singh; Shahid Husain

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 22. doi:

A comparison between injection speed and transient IOP elevation in normotensive eyes receiving intravitreal injections of bevacizumab Open Access

Oliver Fischer; Pearl S Rosenbaum; Zimei Zhou

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 23. doi:

Endothelin-1 Mediated Decrease in Expression of Mitochondrial Proteins ATP5H and COX17 in Retinal Ganglion Cells. Open Access

Renuka Chaphalkar; Dorota L Stankowska; Shaoqing He; Bindu Kodati; Raghu R Krishnamoorthy

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 24. doi:

Electrophysiological Responses of Isolated Retinal Pigment Epithelial (RPE) Cells to Physiological Concentrations of Thiocyanate Open Access

Bret A Hughes; Xu Cao

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 25. doi:

EXN407, a novel topical therapeutic candidate with high retinal bioavailability for the treatment of diabetic macular oedema, inhibits ocular neovascularisation Open Access

Jennifer Batson; Hamish Toop; Susan Liddell; James Daubney; Elizabeth Anne Stewart; Anthony Habgood; Amy Murphy; Ken McKechnie; Jonathan Morris; David O Bates

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 26. doi:

Quantifying retinal and choroidal contributions to macular oxygenation: a theoretical approach Open Access

Alice Chandra Verticchio Vercellin; Alon Harris; Thomas A Ciulla; Greta Chiaravalli; Riccardo Sacco; Brent A Siesky; Ingrida Januleviciene; Giovanna Guidoboni

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 28. doi:

Novel small molecule with neuroprotective activity Open Access

Suchismita Acharya; Adnan Dibas; Zhang Wei; Sai H Chavala

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 29. doi:

Changes in histone deacetylases (HDACs) in glaucomatous optic nerve. Open Access

Wendy Guzman; Sudha Singh; Shahid Husain

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 30. doi:

Modulatory effect of polyphenolic plant compounds on structure and function of rod visual receptor Open Access

Beata Jastrzebska; Joseph T Ortega; Tanu Parmar

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 31. doi:

Can inhibition of phosphodiesterase 6 mimic the oxidative stress phenotype in vivo found in mice with a loss-of-function phosphodiesterase 6 mutation? Open Access

Collin Richards; Hailey Olds; Joydip Joy; Tilman Rosales; Robert H Podolsky; Karen M Lins-Childers; Robin Roberts; Bruce A Berkowitz

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 32. doi:

Azithromycin Protects retinal ganglion cells against Ischemia-Reperfusion induced Injury in rat retina Open Access

Zhenzhen Zhang

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 33. doi:

The role of mTORC1 signaling in retinal bipolar cells Open Access

Jing Li; Yu-Qing Rao

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 34. doi:

Controlled illumination of a PDMS-free Retina-on-a-Chip for the proximity-culture of retinal organoids with pigment epithelial cells Open Access

Johanna Chuchuy; Kevin Achberger; Christopher Probst; Jasmin Haderspeck; Lena Antkowiak; Stefan Liebau; Peter Loskill

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 35. doi:

Evaluation of visual functional changes in eyes with drusen using the Micronized Lipid-Based Carotenoid Liquid Supplementation and AREDS2 Formula Open Access

Drake W Lem; Thomas Henderson; Rebecca Weiss; David W Evans; Stephanie Amonoo-Monney; Pinakin Gunvant Davey

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 36. doi:

Regulation of cytokines and STATs by delta opioid receptor activation in rat glaucoma model. Open Access

Syed A Zaidi; Sudha Singh; Shahid Husain

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 37. doi:

Macular Pigment Reflectometry: A Technique To Measure Peripheral Measurements Open Access

Juan Carlos Sanabria; Jordan Spencer Bass; Frank Spors; Dennis L Gierhart; Pinakin Gunvant Davey

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 38. doi:

NEW FORMULATIONS BASED ON INNOVATIVE BRILLIANT BLUE G DERIVATIVE TO STAIN RETINAL MEMBRANES Open Access

Claudio Bucolo; Filippo Drago; Mario R Romano; Marco Rao; Angelo Spadaro

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 39. doi:

The Endothelin Receptor Antagonist Macitentan Attenuates Vasoconstrictive Effects of Endothelin-1 following Intravitreal Administration in Rodents Open Access

Raghu R Krishnamoorthy; Wei Zhang; Sai Chavala; Dorota L Stankowska

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 40. doi:

The dynamic assessment of retinal structural changes due to heavy physical exercise Open Access

Gabor Mark Somfai; Iren Szalai; Fanni Pálya; Anita Csorba; Edit Bosnyák; Eszter Szendei; Zoltan Zsolt Nagy; Jing Tian; Miklós Tóth; Delia Cabrera DeBuc

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 41. doi:

Effect of Intravitreal Bevacizumab on the Retina Ganglion Cell Layer Open Access

Alice Zhang; Nitin Kumar; Uday Desai

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 42. doi:

Small molecules selectively reduce the misfolded rhodopsin that causes retinitis pigmentosa Open Access

Yuanyuan Chen; Krzysztof Palczewski; Xujie Liu

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 43. doi:

Upregulation of Interleukin-10 (IL-10) by interleukin-1β (IL-1β) in Human Muller cells Open Access

Sofia Noor Habib; Nuwan Niyadurupola; David Charles Broadway; Julie Sanderson

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 44. doi:

Evaluation of Risuteganib as a neuroprotective agent in retinal dystrophy, using the Rabin cone contrast test Open Access

Vanessa Tirado; Luis A. Hernández; Santiago Soberón; Elsa C. Hernández; Jazmin Baca Moreno; Enrique Garcia; Luis Daniel Garcia Arzate; Yurico Lopez; Ana Gonzalez-H.Leon; Ana Suárez Licona; Virgilio Morales-Canton; Hugo Quiroz-Mercado

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 45. doi:

Background Data for P23H Line 1 Heterozygous Rats Raised under Dim Light Conditions for the First 30 Days Post Partum Open Access

Mark Vezina; Tim Bryant; Elridge Edwards; Jonathan Levac; Elen Lebel; Andre-Jean Lambert

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 47. doi:

Pharmacokinetics of intravitreal flurbiprofen in rats with chiral and non-chiral analysis. Open Access

Pavlina Tsoka; Manolis N. Tzatzarakis; Evangelia I. Iatrou; Miltiadis K. Tsilimbaris

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 48. doi:

Sustained oral delivery of ticagrelor (Brilinta) protects against retinal degeneration Open Access

Wennan Lu; Keith Campagno; Leif Carlsson; Claire H Mitchell

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 49. doi:

Retinal Ganglion Cell Losses in an Optic Nerve Crush Model Correlate with Time-Dependent Up-Regulation in phosphorylated c-Jun, c-Jun and Caspase 3. Open Access

Dorette Z Ellis; Linya Li; Yang Liu; Shaoqing He; Thomas Yorio

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 50. doi:

Relationship Between Adult Body Height and Age-Related Macular Degeneration: A Korean Nationwide Population-Based Survey Open Access

Jeong Hun Bae; Incheol Hwang; Muhammad Hassan; Muhammad Sohail Halim; Maria Soledad Ormaechea; Günay Uludağ; Anh NT Tran; Sarakshi Mahajan; Khalid Yusuf Yaseen Al-Kirwi; Rubbia Afridi; Yasir Jamal Sepah; Diana V Do; Quan Dong Nguyen

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 51. doi:

Association of short-term progression in AMD score with risk of development of late AMD and vision loss in the AREDS2 study Open Access

Susan Vitale; Elvira Agron; Traci E Clemons; Amitha Domalpally; Ronald P Danis; Tiarnan D L Keenan; Emily Y Chew

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 52. doi:

Dietary Zinc Intake is Associated with Key Clinical Outcomes in Neovascular Age-Related Macular Degeneration Patients Open Access

Harshil Dharamdasani Detaram; Paul Mitchell; Joanna Russell; George Burlutsky; Nichole Diane Lucy Joachim; Gerald Liew; Bamini Gopinath

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 53. doi:

A further increase of late age-related macular degeneration until 2050 in Europe – a systematic review, meta-analysis and meta-regression Open Access

Jeany Qiuchen Li; Thomas Welchowski; Matthias Schmid; Frank G Holz; Robert P Finger

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 54. doi:

Features of Fear of Falling (FOF) and Balance Self-efficacy in Men and Women with Age-related Macular Degeneration (AMD) Open Access

Claire S Barnes

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 55. doi:

Mail-based Stool Collection in Women with and without Age-Related Macular Degeneration (AMD) Open Access

Amy E Millen; Kristen Hall; Kelly B Kamm; Zhe Liu; Barbara J Krajewski; Jean Wactawski-Wende; Gareth Lema; Michael Buck; Rachael Hageman Blair; Yijun Sun; Daniel McSkimming; Julie A Mares

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 56. doi:

Higher Intake of Polyunsatruated Fatty Acid and Monounsaturated Fatty Acid is inversely assoicated with presence of Age-related Macular Degeneration Open Access

Miin Roh; Hyun Joon Shin; Ines Lains; Joana Providência; Eduarda Caseiro-Alves; Patricia Barreto; Carla Lopes; Demetrios Vavvas; John B Miller; Ivana K Kim; Liming Liang; Rufino Silva; Joan W Miller; Deeba Husain

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 57. doi:

Incidence of age-related macular degeneration in the central region of Portugal: the Coimbra Eye Study – report 5 Open Access

Claudia Farinha; Maria Luz Cachulo; Dalila Alves; Isabel Pires; Jo�o Pedro Marques; Patricia Barreto; Sandrina Nunes; Jose Costa; Amelia Martins; Isa Sobral; Ines Lains; Joao Figueira; Maria Luisa Ribeiro; Jose G Cunha-Vaz; Rufino Silva

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 58. doi:

Association of medications and neovascular age-related macular degeneration: National Sample Cohort 2010-2015 Open Access

Jiyong Kwak; Tyler Hyungtaek Rim; Tae Keun Yoo; Sung Eun Kim; Dong Wook Kim; Sung Soo Kim

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 59. doi:

High-Dose Statins and Progression of Age-Related Macular Degeneration in Commercially Insured Patients, 2007 to 2016 Open Access

Cassie A. Ludwig; Nitya Rajeshuni; Daniel Vail; Natalia F. Callaway; Darius Moshfeghi

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 60. doi:

Effect of Proliferative Diabetic Retinopathy on Development of Neovascular AMD: a Big Data Analysis Open Access

Frank Brodie; Laurel Stell; Mohajeet Bhuckory; Valentina Zuckerman; Efstathios Vounotrypidis; Steven Sanislo; Daniel V Palanker

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 61. doi:

Seasonal variation of first presentation with neovascular age-related macular degeneration Open Access

Roy Schwartz; Tjebo Heeren; Adnan Tufail; Catherine A Egan

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 62. doi:

Prevalence of Age-related macular degeneration using multi-modal retinal imaging in a population based aging cohort: the NICOLA Study Open Access

Ruth Esther Hogg; Nicola B Quinn; Tunde Peto; DAVID WRIGHT; Bernadette McGuinness; Ian Young; Frank Kee; Usha Chakravarthy

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 63. doi:

The Association between Late Age-Related Macular Degeneration and Hospital Admission in the California Medicare Database Open Access

Alejandro Ochoa III; Fei Yu; Victoria Tseng; Ken Kitayama; Anne L Coleman

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 64. doi:

Clinical Manifestation of Cuticular Drusen in Korean Patients Open Access

Donghoon SHIN; Don-Il Ham

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 65. doi:

Subretinal drusenoid deposits in the elderly in a population-based study (the Montrachet study: Maculopathy, Optic Nerve, nuTRition, neurovAsCular and HEarT diseases) Open Access

Pierre-Henry GABRIELLE; Alassane Seydou; Louis Arnould; Niyazi Acar; Christine Binquet; Alain M Bron; Catherine Creuzot-Garcher

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 66. doi:

The National Eye Institute Visual Function Questionnaire-25 in Patients with Age-Related Macular Degeneration and Controls Open Access

Jennifer Patnaik; Paula Pecen; Anne Lynch; Frank Siringo; Marc Mathias; Naresh Mandava

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 67. doi:

Is Polypoidal Choroidal Vasculopathy differentiated from Age-related Macular Degeneration? Open Access

Handan Akil; Tony Fang; Theresa Wiens; David Maberley; Eduardo Vitor Navajas

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 68. doi:

Sociodemographic disparities in presenting visual acuity of neovascular age related macular degeneration patients Open Access

Meera Diana Sivalingam; Kalla A Gervasio; Connie M Wu; Douglas Matsunaga; Joshua Uhr; Anthony Obeid; Turner D Wibbelsman; Hannah Levine; Ravi R Pandit; Thomas Jenkins; David Xu; Jason Hsu; Allen C Ho

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 69. doi:

Prevalence and associated factors of age-related macular degeneration in a Russian Population. The Ural Eye and Medical Study Open Access

Rinat Zainullin; Mukharram Bikbov; Timur Gilmanshin; Gyulli Kazakbaeva; Ellina Rakhimova; Kamilla Safiullina; Songhomitra Panda-Jonas; Iulia Rusakova; Natalia Bolshakova; Guzel Bikbova; Jost B Jonas

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 70. doi:

Updated incidence rates of legal blindness from age-related macular degeneration in Denmark: 2010-2016 Open Access

Michael Larsen; Sara Brandi; Inger Christine Munch

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 71. doi:

Dietary intake of saturated fatty acid and early age-related macular degeneration in a Japanese population. Open Access

Mariko Sasaki; Sei Harada; Yumiko Kawasaki; Kazuo Tsubota; Toru Takebayashi; Yuji Nishiwaki; Ryo Kawasaki

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 72. doi:

Two year outcomes of the integrated management scheme for AMD clinics and patient feedback with Eylea treatment protocol - The Swindon model Open Access

Hani Hasan

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 73. doi:

Factors Associated with Extended Remission in Neovascular Age-Related Macular Degeneration on Pro Re Nata Treatment Protocol Open Access

Tiezhu Lin; Kunny Dans; Ilkay Kilic Muftuoglu; Amit Meshi; Manuel Amador; Lingyun Cheng; William R Freeman

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 74. doi:

Pigment Epithelial Detachments Response to a Single Ranibizumab Injection: a HARBOR Subanalysis Open Access

Michael Javaheri; Lauren Hill; Avanti Ghanekar; Ivaylo Stoilov

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 75. doi:

Anti-VEGF Non-Responders are often short-term responders Open Access

Saghar Bagheri; Georgios Bontzos; Larisa Ioannidi; Stamatina Kabanarou; Ivana K Kim; Evangelos S Gragoudas; Joan W Miller; IOANNIS DATSERIS; Miltiadis K. Tsilimbaris; Demetrios Vavvas

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 77. doi:

Changes in the inner retinal layer thickness in patients with exudative age-related macular degeneration during treatment with intravitreal anti-vascular endothelial growth factor accordi... Open Access

Jae Yong Park; BUMGI KIM; Jae Suk Kim; Miryoung Song; Je Hyung Hwang; In Beom Jang; Won Hyuk Oh

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 78. doi:

A randomised clinical trial of slow versus fast intravitreal injection of ranibizumab (Lucentis®) and its impact on intraocular pressure (the Speed IOP Study) Open Access

Samantha Fraser-Bell; Sophia Zagora; Hemal Mehta; Anna Campain; Hon Seng Wong; Yeung Aaron; Mark C Gillies

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 79. doi:

Short-Term Outcomes of Eyes with Neovascular Age-related Macular Degeneration (nAMD) that Switched from Aflibercept to Ranibizumab Open Access

Jason Hsu; Anthony Obeid; Phoebe L Mellen; Turner D Wibbelsman; Michelle A. Konkoly; Michael R. Velez; Daniel B. Calem; Kareem Sioufi; Daniel Su; Philip Storey; Michael A. Klufas; Marc J. Spirn; Carl Regillo; Allen C Ho

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 80. doi:

Three-year Outcomes of Treat and Extend Aflibercept Treatment for Neovascular Age-related Macular Degeneration Open Access

Keiko Kataoka; Keiko Asai; Yuma Tsunekawa; Yasuki Ito; Hiroko Terasaki

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 81. doi:

Real-life long-term outcomes for patients receiving intra-vitreal Aflibercept for neovascular age related macular degeneration (nAMD): five(5)-year follow-up Open Access

Ankur Mehta; Matthew Hartley; Majed Habib; Ajay Kotagiri; David Steel; Smith Jonathan; Deepali Varma

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 83. doi:

Fequency of intra- and extralesional macular atrophy in the IVAN Follow-up trial Open Access

Tunde Peto; Rebecca Evans; Barney Reeves; Usha Chakravarthy

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 84. doi:

Individualizing therapy for neovascular age-related macular degeneration with aflibercept (the VITAL study): A two year prospective, interventional single-centre trial Open Access

Simona Degli Esposti; Maria K Gemenetzi; Maria Eleftheriadou; Hari Jayaram; Bishwanath Pal; Niaz Islam; Peter Addison; Robin Hamilton; Praveen Patel

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 85. doi:

10-year Mortality and Clinical Outcomes in Patients with Neovascular Age-related Macular Degeneration Treated with Intravitreal Anti-VEGF Injections. Open Access

Su Ling Young; Martin Anderson; Shyamanga Borooah; Ana Maria Ambrecht; Peter D Cackett

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 86. doi:

Post-injection endophthalmitis rates with reduced povidone-iodine prophylaxis in patients with self-reported iodine allergy Open Access

Sarah Schimansky; Irene Mary Stratton; Emily Fletcher; Quresh Mohamed

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 87. doi:

Outcomes of cataract surgery in patient with wet age-related macular degeneration while being treated with intravitreal Aflibercept with treat-and-extend regimen. Open Access

Tatsuya Nagai; Tomohiro Nizawa; Masayasu Kitahashi; Takayuki Baba; Shuichi Yamamoto; Takehito Iwase

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 88. doi:

Psychological impact of treat-and-extend ranibizumab therapy in patients with age-related macular degeneration Open Access

SATOSHI KUWAYAMA; Aki Kato; Tsutomu Yasukawa; Iichiro Sugita; Munenori Yoshida; Miho Nozaki; Yoshio Hirano; Junko Kondo; Tomohiro Abe; Kimiko Sugita; Takahide Okita; Hiroshi Morita; Kazuhiko Sugitani; Naomi Inoue; Noriaki Takase; Yuichiro Ogura

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 89. doi:

Association Between Early Vision-Related Quality of Life Outcomes and Anatomic Dryness Response in Neovascular Age-Related Macular Degeneration (nAMD): A Post-Hoc Analysis of VIEW Trials Open Access

David Aaron Eichenbaum

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 90. doi:

Twelve percent of 6142 patients treated for neovascular age-related macular degeneration (nAMD) presented with low visual outcome within two years. Analysis from the Swedish Macula Regist... Open Access

Marion Schroeder; Monica Karin Loevestam-Adrian

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 91. doi:

Change in 1-year visual acuity gain with age-related macular degeneration from 2006 and 2015 Open Access

Sachi Nishino; Tsutomu Yasukawa; Hiroko Imaizumi; Hisashi Mastubara; Hiroto Ishikawa; Kazuhiro Kimura; Hiroto Terasaki; Yoshinori Mitamura; Toshinori Murata; Mariko Yamashita; Jiro Kogo; Masaru Takeuchi; Yoshihiro Takamura; Tomoya Murakami; Taiji Sakamoto; Masahito Ohji

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 92. doi:

Patient Preferences for Anti-VEGF Treatment Regimens for Wet Age-Related Macular Degeneration in Japan Open Access

Yuji Oshima; Takeshi Joko; Yoshimi Nagai; Ryusaburo Mori; Koji Tanaka; Yusuke Hikichi; Tetsushi Komori; Joao Carrasco; Martine Maculaitis; Oliver Will; Kathleen Beusterien; Kanji Takahashi

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 93. doi:

One-year efficacy of anti-vascular endothelial growth factor agents in patients with neovascular age-related macular degeneration: a meta-analysis and meta-regression. Open Access

Daniele Veritti; Valentina Sarao; Carla Danese; Paolo Lanzetta

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 94. doi:

Intravitreal Aflibercept in a Routine Treat and Extend (T&E) Regimen for Treatment-Naïve wet AMD Patients: 2-Year Outcomes of the observational ASTERIA Study Open Access

Andreas Ebneter; Stephan Michels; Pascal Imesch; Felix Eilenberger; Susanne Oesch; Christian Prünte; Katja Hatz

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 95. doi:

Combination therapy with intravitreal tissue plasminogen activator and ranibizumab for wet age-related macular degeneration with subretinal hyperreflective material Open Access

Ryoko Takeuchi; Tsutomu Yasukawa; Aki Kato; Tomohiro Obayashi; Satoshi Kuwayama; Soichiro Kuwayama; Norihiro Suzuki; Noriaki Takase; Naomi Inoue; Kazuhiko Sugitani; Yoshio Hirano; Munenori Yoshida; Yuichiro Ogura

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 96. doi:

Impacts of cataract surgery in eyes treated by anti-vascular endothelial growth factor therapy for wet age-related macular degeneration on visual outcomes Open Access

Tomohiro Obayashi; Tsutomu Yasukawa; Ryoko Takeuchi; Miho Inagaki; Katsuya Suzuki; Noriaki Takase; Naomi Inoue; Aki Kato; Hiroshi Morita; Yoshio Hirano; Miho Nozaki; Munenori Yoshida; Yuichiro Ogura

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 97. doi:

Assessing the Efficacy and Safety of Intravitreal Dexamethazone Implant in Treating Macular Edema in Eyes with an Incomplete Response to Anti-vascular Endothelial Growth Factor Agents. Open Access

Walid Abdallah; Mark Barakat; David Goldenberg; Sujit Itty; Pravin U Dugel; Karim Jamal; Derek Kunimoto; Sachin Mehta; Edward Quinlan; Neal Palejwala

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 98. doi:

Anatomic and functional results with Aflibercept in poor-responders to Ranibizumab with long term recurrent neovascular AMD Open Access

Laura Andrea Lima Modino; Gabriela Estefania Pacheco Callirgos; Carlos Daniel Blando Labrandero; María Isabel López Gálvez

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 99. doi:

Treat-and-extend anti-VEGF therapy for exudative age-related macular degeneration: long-term results Open Access

Sandra DELAUNAY; Frank Becquet; Sophie Dupouy; Elisabeth Hermouet-Leclair; Idriss Badat; Jean-François Le Rouic

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 100. doi:

Efficacy of the Treat-and-Extend Regimen in the Management of Neovascular Age-related Macular Degeneration: 5-year Results of the RENO Study Open Access

Jonathan Dang; Arshad M. Khanani; Greggory Gahn; Micaela Koci; Nazrul Mojumder; Sylvia Phillips; Lauren Hill

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 101. doi:

Are patients with wet AMD as satisfied following a switch from Treat and Extend to Observe and Plan protocol? Open Access

Alietha Vorren; Dordi Austeng; Tora Sund Morken

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 102. doi:

Outcomes of quarterly anti-VEGF dosing for nAMD management in real-world clinical practice Open Access

Alexander Michael Rusakevich; Brenda Zhou; Charles Clifton Wykoff

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 103. doi:

Factors predictive of visual outcome and retreatment of polypoidal choroidal vasculopathy 6 years after photodynamic therapy combined with intravitreal injection of anti-vascular endothel... Open Access

Wataru Kikushima; Yoichi Sakurada; Naohiko Tanabe; Atsushi Sugiyama; Mio Matsubara; Hiroyuki Iijima

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 104. doi:

Prognostic factors associated with long-term results of intravitreal ranibizumab combined with photodynamic therapy for treatment-naïve polypoidal choroidal vasculopathy Open Access

Atsushi Okubo; Ryo Obata; keiko azuma; Tatsuya Inoue

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 105. doi:

Clinical outcome of switching from ranibizumab to aflibercept in the treatment of neovascular age-related macular degeneration Open Access

Lin Lu; Gnanaruban Muthulingam; Claire Osborne; Prabhu Tonne; Gopinath Reddy; Maharatnam Logendran

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 106. doi:

A highly soluble and fully modified aptamer that targets all VEGF-A isoforms for treating retinal diseases Open Access

Jinpeng Wang; Qin Yang; Jingwen Yu; Hui Kang; Matthew Vukovich; Wen-Chuan Chou; Scott Ferguson; Qiang Gong

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 107. doi:

Changes in the SOD2, HIF1α and VEGFA gene expression in wet AMD cybrid cells after treatment with aflibercept or ranibizumab. Open Access

Jaime Toledo Corral; Rami San Gabriel; Paula Sakemi Fukuhara; Noor-Ul-Ain Shekoh; Tamer Hadi; Cristina Kenney; Baruch D Kuppermann

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 108. doi:

Survey of Intravitreal Injection Practice Patterns among Retina Specialists Open Access

Stephen J Smith; Therese Sassalos; Nish Patel; Chris Andrews; David C Musch; Cagri G Besirli

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 109. doi:

Macular Atrophy Affecting Visual Outcomes in Patients Undergoing Anti-VEGF Treatment Open Access

Weilin Song; Nathaniel B. Rieveschl; Ang Li; Thais Conti; Grant L Hom; Rishi P Singh

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 110. doi:

Ten-Year Treatment Outcomes of Neovascular Age-Related Macular Degeneration Open Access

Mark C Gillies; SANJEEB BHANDARI; Benjamin Wolff; Jennifer Joan Arnold; Rohan W Essex; Stephanie Young; David M Squirrell; Daniel Barthelmes; Vuong Nguyen

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 111. doi:

High-Dose High-Frequency Aflibercept For Recalcitrant Neovascular Age-Related Macular Degeneration (2-year follow up) Open Access

Manuel Amador; Mahima Jhingan; Amit Meshi; Kunny Dans; Tiezhu Lin; Melina Cavichini Cordeiro; William R Freeman

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 112. doi:

Volume evaluation of additional Anti-VEGF agents released when the plunger is double squeezed Open Access

Miryoung Song; Jae Suk Kim; Je Hyung Hwang; Won Hyuk Oh; Jae Yong Park; BUMGI KIM

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 113. doi:

A Novel Long-Acting Drug Conjugate for Extended Anti-VEGF Therapy Open Access

Wesley M Jackson; Livia W Brier; Amy Twite; Mavish Mahomed; Ricardo Lamy; Matilda F Chan

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 114. doi:

Interleukin-8 production by cells in peripheral blood is associated with age-related macular degeneration lesion activity during anti-VEGF treatment and with variants of the interleukin-8... Open Access

Ilkka J Immonen; Alexandra Robciuc; Jarno Kivioja; Jukka Moilanen; Sanna Seitsonen; Irma Järvelä; Asta Hautamäki

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 115. doi:

Anatomical outcomes of patients receiving 50 or more intravitreal anti-VEGF injections for neovascular age-related macular degeneration Open Access

Cristina Arpa; Gabriella Moraes; Katrin Fasler; Dun Jack Fu; Siegfried Karl Wagner; Konstantinos Balaskas; Pearse Andrew Keane

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 116. doi:

Efficacy of Intravitreal Aflibercept Administered using Treat-and-Extend Regimen over 2 Years in Patients with Neovascular Age-Related Macular Degeneration: 1-Year ARIES Results. Open Access

Paul Mitchell; Eric H Souied; Edoardo Midena; Frank G Holz; Philip G Hykin; Sebastian Wolf; Helmut Allmeier

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 117. doi:

Predictors of five-year visual outcome for exudative age-related macular degeneration treated with intravitreal aflibercept using treat and extend regimen. Open Access

Manabu Yamamoto; Takeya Kohno; Kumiko Hirayama; Shigeru Honda

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 118. doi:

TEN-YEAR RESULTS OF WET AGE-RELATED MACULAR DEGENERATION ANTI-VEGF TREATMENT Open Access

Heinrich Gerding; Lars Hefner; Melanie Timmermann; Katarina Hurtikova; Gabor Somfai

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 119. doi:

High-Frequency Anti-VEGF Treatment for Neovascular AMD Open Access

Dillion Matthews; Kapil G. Kapoor; Alan Wagner

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 120. doi:

Quantification of Anterior Chamber Reaction after Intravitreal Injections of Conbercept and Ranibizumab: a pilot study Open Access

Haoyu Chen; Xulong Liao; Chuang Jin; Weiqi Chen; Guihua Zhang; Lingping Cen; Siu Chun Danny Ng

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 122. doi:

Long-term treatment patterns and visual outcomes of anti-vascular endothelial growth factor agents among people with neovascular age-related macular degeneration in the US Open Access

Adrian Skelly; Arshad M. Khanani; Raymond Griner; Vladimir Bezlyak; Julie Clark; Alexandros Sagkriotis

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 123. doi:

Long-term follow up or macular neovascularization using optical coherence tomography angiography: Pro Re Nata versus Treat&Extend regimens Open Access

Pierre Sustronck; Alexandra Miere; Hassiba Oubraham; Eric H Souied

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 124. doi:

Macular atrophy in neo-vascular AMD – incidence and risk factors related to treatment Open Access

Oliveira Almeida Oliveira; Claudia Farinha; Tiago Rodrigues; Amelia Martins; Maria Luz Cachulo; Jo�o Pedro Marques; Isabel Pires; Rufino Silva

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 125. doi:

Chronic Nonclinical Ocular Toxicity Study of KSI-301 Demonstrates Tolerability after Intravitreal Administration in Cynomolgus Monkeys Open Access

John Sinclair; hong liang; zachary antonio; paul miller; avery tolosa; joel naor; leah quarberg; alok sharma; Xiaojian Huang; Janine Lu; William Ngo; dan dang; frances clemo; James N Ver Hoeve; T. Michael Nork; D. Victor Perlroth

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 126. doi:

Rhegmatogenous retinal detachment in active neovascular age-related macular degeneration Open Access

Danny Mammo; Alexander L Ringeisen; D. Wilkin Parke III

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 127. doi:

Drug Testing in the Virtual Eye Open Access

Simon Dörsam; Gerd U. Auffarth; Elfriede Friedmann

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 128. doi:

A new phenotype of atypical wet age-related macular degeneration Open Access

Bishwanath Pal; Filipa Rodrigues; Hagar Khalid

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 129. doi:

The efficacy of treatment with aflibercept intravitreal injections in patients with wet age-related macular degeneration Open Access

Anna Heinke

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 130. doi:

Intraocular pressure trends in the Canadian treat and extend trial with ranibizumab in patients with nAMD: CANTREAT study 24-month results Open Access

Peter Kertes; Tom Sheidow; Geoff Williams; Mark Greve; Ivan Galic; Emmanouil Rampakakis; Marcel Lahaie

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 131. doi:

A Novel Surrobody Reduces Neovascularization in a Rat Model of CNV Open Access

Anthony Abraham Jones; Joshua L. Morgenstern; Anne D. Strong; Jeffrey Olson

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 132. doi:

Visual Acuity Outcomes of Fellow Eyes Treated for New Onset Neovascular Age-Related Macular Degeneration in Patients in the RENO study Open Access

Nazrul Mojumder; Jonathan Dang; Arshad M. Khanani; Greggory Gahn; Micaela Koci; Sylvia Phillips; Lauren Hill

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 133. doi:

Correlation of BCVA and SRF in Type 1 CNV(Choroidal Neovascularisation) with Pachychoroid Features Open Access

Virinder Kaur Dhillon; Angela Ding Wu; Bishwanath Pal

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 134. doi:

Treatment of type 3 choroidal neovascularization with intravitreal injections of Aflibercept : a prospective study.

Open Access

Nicolas Leveziel; Rania Warrak; Emilie Bedue; Melodie Omar; Pierre Ingrand

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 135. doi:

Treatment and Management of Neovascular AMD: Impact on Patients Open Access

Vincent W Li; Isaac R. Gabriel; Madeleine M Li; Andrew N Antoszyk; Carl W Baker; Pravin U Dugel; Roger A. Goldberg; Jeffrey S. Heier; Allen C Ho; John S Pollack; Charles Clifton Wykoff; Demetrios Vavvas; William W Li

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 136. doi:

Thermo-sensitive hydrogel for the controlled release of Aflibercept: in vitro release and ex vivo bioactivity Open Access

Xinxin Zhao; Kun Xue; Xinyi Su

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 137. doi:

Significant Correlation between Ganglion Cell Layer & Inner Plexiform Layer Thickness and Retinal Sensitivity Changes After Intravitreal Aflibercept Treatment in Eyes with Exudative A... Open Access

Rie Osaka; Chieko Shiragami; Aoi Ono; Yukari Takasago; Mamoru Kobayashi; Ayana Yamashita; Saki Manabe; Akitaka Tsujikawa; Kiyoshi Suzuma

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 138. doi:

Outcomes of suspending VEGF inhibitors for neovascular age-related macular degeneration when lesions have been inactive for 3 months Open Access

Vuong Nguyen; Anagha Vaze; Samanta Fraser-Bell; Jennifer Joan Arnold; Rohan W Essex; Daniel Barthelmes; Mark C Gillies

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 139. doi:

Automated multimodal registration of OCT en face and color fundus images Open Access

Reza Jafari; Qi Yang; Charles A Reisman

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 140. doi:

Full Range Optical Coherence Tomography by Optical Path Difference Sweep Open Access

Naoki Takeno; Shinya Iwata; Ryosuke Shiba; Koichi Ito; Masaaki Hanebuchi

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 141. doi:

Optical coherence tomography shape analysis describes myopic retinal shape Open Access

Stewart Lake; Murk Bottema; Keryn Williams; Karen Reynolds

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 142. doi:

A method for automated choroidal-scleral interface segmentation in optical coherence tomography Open Access

Homayoun Bagherinia; Giovanni Gregori; Philip J. Rosenfeld; Cancan Lyu; Jila Noorikolouri; Yingying Shi; Fang Zheng; Luis De Sisternes; Mary K Durbin

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 143. doi:

Speckle Noise Reduction in Visible-Light OCT Open Access

Jenna Tauber; Roman Kuranov; Ian Rubinoff; Yuanbo Wang; Zeinab Ghassabi; Katie Lucy; Hao F Zhang; Gadi Wollstein; Joel S Schuman; Hiroshi Ishikawa

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 144. doi:

Variability and repeatability of inner retinal macula layers segmentation by SD-OCT Open Access

Radouil T Tzekov; Keith Zimmerman; David Richards; Ramesh Ayyala

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 145. doi:

Clinical implementation of malarial retinopathy screening system for improved diagnosis of cerebral malaria Open Access

Vinayak S Joshi; Jeffrey C Wigdahl; Sheila C Nemeth; Gilberto Zamora; Peter Soliz; Susan Lewallen; Simon P Harding; Benjamin Turner; Chatonda Manda; Terrie Taylor

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 146. doi:

Comparison of OCTA algorithms for detecting vascular and non-vascular flow signal on hyperreflective lesions in diabetic retinopathy Open Access

Xiang Wei; Qisheng You; Acner Camino; Jie Wang; Christina J Flaxel; Steven T Bailey; David Huang; Thomas S Hwang; Yali Jia

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 147. doi:

Enhancing visibility of choroidal vasculature in OCT via attenuation compensation and coherence transport inpainting Open Access

Jianlong Yang; Xiaoxi Mu; Yitian Zhao; Fei Li; Liyang Fang; Yan Hu; Jun Cheng; Xiulan Zhang; Jiang Liu

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 148. doi:

A theoretical study of vascular configurations of retinal capillary plexi based on OCTA data Open Access

Greta Chiaravalli; Giovanna Guidoboni; Riccardo Sacco; Thomas A Ciulla; Alon Harris

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 149. doi:

Investigation of parameters to quantify local variations in the circumpapillary retinal nerve fiber layer on OCT circle scans of eyes with early glaucoma. Open Access

William Eugene McKee; Emmanouil Tsamis; Katherine Tsang; C Gustavo De Moraes; Donald C Hood

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 150. doi:

Intergrader reproducibility of peripapillary retinal metrics from optical coherence tomographic angiography in community dwelling older adults Open Access

Saleema Kherani; Richey Sharrett; Xinxing Guo; Qisheng You; Liang Liu; David Huang; Pradeep Y Ramulu; Alison Abraham; Xiangrong Kong

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 151. doi:

Automated Bruch’s membrane segmentation in OCT volumes with choroidal neovascularization. Open Access

Jenwei Kuo; Qi Yang; Wei Chieh Huang; Charles A Reisman

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 152. doi:

Nerve fiber layer thickness in young subjects with poor fixation; resampling misaligned scans Open Access

John P Kelly; Francine Baran

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 153. doi:

Correlation between Retinal Nerve Fiber Layer Thickness of Different Parapapillary Regions and the Age Open Access

Chen LIN; Qing-Qiang LI; Wei Huang

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 154. doi:

Fast and memory-efficient Just-Enough Interaction for retinal layer segmentation in OCT in layer-disrupting pathology Open Access

Kyungmoo Lee; Honghai Zhang; Zhihui Guo; Andreas Wahle; Hrvoje Bogunović; Sebastian M Waldstein; Bianca S Gerendas; Ursula Schmidt-Erfurth; Michael David Abramoff; Milan Sonka

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 155. doi:

Real-time retinal layer segmentation for high-resolution OCT angiography Open Access

Worawee Janpongsri; Morgan Heisler; Myeong Jin Ju; Marinko V Sarunic; Yifan Jian

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 156. doi:

Optic Disc Tracking in SLO/OCT Videos Open Access

Chen Gong; John P Kelly; Steven Brunton; Eric Seibel

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 157. doi:

Asynchronous Remote Adjudication for Grading Diabetic Retinopathy Open Access

Mike Schaekermann; Naama Hammel; Brian Basham; Bilson Campana; Edith Law; Lily Peng; Dale R Webster; Rory Sayres

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 158. doi:

Distinguishing cognitive impairment with multifractal complexity of the retinal vascular network Open Access

Delia Cabrera DeBuc; Edmund Arthur; Gabor Mark Somfai; Maja Kostic; Susel Oropesa; Carlos Mendoza-Santiesteban

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 159. doi:

Characterization of macular edema in the initial stages of diabetic retinopathy Open Access

Torcato Santos; Ines Marques; Ana Rita Santos; Dalila Alves; Conceição Lobo; Jose G Cunha-Vaz

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 160. doi:

Construction of Digital Video Fluorescein Angiography for Quantitative Analysis of Retinal Blood Flow Open Access

Hanjo Kwon; Ji Eun E Lee

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 161. doi:

Integration of Artificial Intelligence and OpacitySuppression^TM Software in Tele-Retinal Screenings Open Access

Andrew Caterfino; Ashley Ooms; Sameer Trikha; Brian Caterfino; Ben Szirth; Albert S Khouri

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 162. doi:

Quantitative analysis of fundus images as affected by cataract Open Access

Lydia Mineeva; Christopher L Passaglia; Leonid Balashevich; David Richards; Leonid Shubin; Andrey Kabanov; Brian Madow; Erin Greenberg

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 163. doi:

A Study of Feature-based Consensus Formation for Glaucoma Risk Assessment Open Access

Naama Hammel; Mike Schaekermann; Sonia Phene; Carter Dunn; Lily Peng; Dale R Webster; Rory Sayres

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 164. doi:

Corneal Confocal Image Fusion Open Access

Simone Pajaro; Giulia Menin; Michele Pascolini

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 165. doi:

Chromatic vs monochromatic blue fundus Autofluorescence in patients with cataract Open Access

Marco U Morales; Andrea Muraca; Ceterina Toma; Enea Poletti; Stefano De Cillà; Winfried M K Amoaku; Stela Vujosevic

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 166. doi:

Fully automated segmentation algorithm for corneal nerves analysis from in-vivo UHR-OCT images Open Access

Zohreh Hosseinaee; Le Han; Olivera Kralj; Alexander Wong; Luigina Sorbara; Kostadinka K Bizheva

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 167. doi:

Automated structure-function analysis of OCT and microperimetry data using intensity-based image registration Open Access

Jovi Wong; Prashant Pandey; Mary Lou Jackson; Claire Sheldon

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 168. doi:

Performance evaluation of multi-retinal layer segmentation using SD-OCT Open Access

Ting Luo; Homayoun Bagherinia; Ali Fard; Jason Anderson; Yijun Huang; Katherine Makedonsky; Mary K Durbin

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 169. doi:

Estimating the Shape of the Human Foveola Open Access

Brett A Davis; Hamish J McNeill; Jared Hamwood; Michael J Collins

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 170. doi:

Measurement of optical scattering properties of retinal layers Open Access

Jeremy D Rogers

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 171. doi:

Validating Laser Speckle Contrast Imaging as a Quantitative Tool for Measuring Retinal Vascular Function in Rodents Open Access

Dwani Patel; Thomas B. Connor; Daniel M. Lipinski

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 172. doi:

Retinal pulsatile shift enhancement with blind source separation Open Access

Ivana Labounkova; Rene Labounek; Jan Odstrcilik; Michal Hracho; Igor Nestrasil; Ralf P Tornow; Radim Kolar

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 173. doi:

Pattern recognition for the distinction of drusen from reticular pseudodrusen Open Access

Angelica Ly; Lisa Nivison-Smith; Michael Kalloniatis

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 174. doi:

The Prospective Imaging Quantification of Ocular Inflammation (IQI) Study Open Access

Sunil K Srivastava; Kimberly Baynes; Sumit Sharma; Arthi Venkat; Careen Lowder

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 175. doi:

High resolution Scanning Laser Ophthalmoscope imaging with ultrafast retinal tracking Open Access

Maciej Szkulmowski; Maciej Nowakowski; Krzysztof Dalasinski; Maciej M Bartuzel; Krystian Wrobel; Szymon Tamborski; Ewelina Pijewska; Anna Szkulmowska

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 176. doi:

Fully Convolutional Segmentation of Corneal Limbus and Foveal Blood Vessels in Fluorescein Angiography Open Access

Yalin Zheng; Hanjie Yao; Yaochun Shen; Yitian Zhao; Bryan Williams

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 177. doi:

Non-mydriatic structured light imaging of the retina with the Digital Light Ophthalmoscope Open Access

Matthew S Muller; Joel Papay; Robert N Gilbert; Thomas Gast; Ann E Elsner

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 178. doi:

Euclidean distance method for retinal amyloid polarimetry segmentation Open Access

Erik Mason; Melanie C W Campbell

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 179. doi:

Confocal and multiply scattered light imaging with the Digital Light Ophthalmoscope Open Access

Joel Papay; Matthew S Muller; Robert N Gilbert; Thomas Gast; Ann E Elsner

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 180. doi:

Prediction of Late Dry and Wet Age-related Macular Degeneration (AMD) in 1-year and 2-year Incident using Retinal Imaging and Traditional Risk Factors Open Access

Alauddin Bhuiyan; Arun Govindaiah

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 181. doi:

Robust Alignment of Retinal Sequential Multispectral Images Open Access

Yu Wang; Yanhui Ding; Wanzhen Jiao; Fang Yan; Bojun Zhao; Yuanjie Zheng

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 182. doi:

Multiphoton microscopy for three dimensional histology of retinal whole mounts Open Access

Chintan Patel; Rick Torres; Eben Olson; Michael Levene; Matthew S Lawrence

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 183. doi:

Outer Retinal Oxidative Stress Measured In Vivo using QUEnch-assiSTed (QUEST) OCT Open Access

Haohua Qian; Robert H Podolsky; Karen M Lins-Childers; Yichao Li; Bruce A Berkowitz

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 184. doi:

Mouse corneal topography, pachymetry, and keratometry utilizing OCT with keratometer validation Open Access

Alice Sicong Liu; Dillon Brown; Rachel Elizabeth Conn; Ryan P McNabb; Machelle T Pardue; Anthony N Kuo

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 185. doi:

Functional and Ultrastructural Assessment of Novel OCT Findings in the Cynomolgus Monkey Open Access

Helen Booler; Aija M. Kusi; Nardos Tassew; Christopher Frantz; Matthew Holdren; Phillip Lai; T. Michael Nork; Carol Rasmussen; William Meier; Vladimir Bantseev

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 186. doi:

Monitoring Retinal Responses to Acute Intraocular Pressure Elevation in Rats with Visible Light Optical Coherence Tomography Open Access

Shaohua Pi; Tristan Hormel; Xiang Wei; William Cepurna; Acner Camino; Yukun Guo; David Huang; John C Morrison; Yali Jia

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 187. doi:

Retinal thickness increases in anesthetized but not awake-behaving mice Open Access

GUANPING FENG; Jesse B Schallek

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 188. doi:

Optimization and validation of a novel technique for in vivo imaging of FITC-dextran labelled erythrocytes in non-human primates Open Access

Elise L. Ma; Lakyn Mayo; Xiaoxuan Fan; Karen Underwood; Steven L Bernstein; Osamah Saeedi

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 189. doi:

Multimodal longitudinal in vivo retinal and cerebral imaging-based framework for neurodegenerative diseases using mouse model of Alzheimer's Disease Open Access

Da Ma; Sieun Lee; Daniel J Wahl; Ahmad Sidiqi; Andrew Yung; Joanne A Matsubara; Piotr Kozlowski; Mirza Faisal Beg; Marinko V Sarunic

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 190. doi:

Retinal Oxygen Delivery, Metabolism, and Extraction Fraction During Long-term Bilateral Common Carotid Artery Occlusion in Rats Open Access

Sophie Leahy; James Burford; Shayan Farzad; Norman P Blair; Mahnaz Shahidi

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 191. doi:

Characterization of a mouse model of RPE pathology Open Access

Ivana Arellano; Hui Li; Jorge Aranda; Shawn Hanks; Tim Pagliaro; Joanna Vrouvlianis; Nalini V Rangaswamy; Chad E Bigelow; Stephen H Poor

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 192. doi:

Assessing longitudinal changes in the SOD1 knock-out mouse model by OCT imaging Open Access

Marco Augustin; Danielle J. Harper; Conrad W. Merkle; Christoph K Hitzenberger; Martin Glösmann; Bernhard Baumann

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 193. doi:

A longitudinal study of in vivo fluorescence imaging of curcumin-labeled amyloid beta deposits in the retina of an Alzheimer mouse model Open Access

Ahmad Sidiqi; Daniel J Wahl; Sieun Lee; Da Ma; Elliott To; Sijia Cao; Eleanor To; Jing Z Cui; Mirza Faisal Beg; Marinko V Sarunic; Joanne A Matsubara

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 194. doi:

Visualization of three-dimensional microcirculation of rodents’ retina for study of critical illness using optical coherence tomography angiography Open Access

Jang Ryul Park; Yongjoo Kim; Kyuseok Kim; Wangyuhl Oh

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 195. doi:

Real-time guidance and monitoring of CNV through subretinal injection in rabbit eyes using multimodal PAM and OCT imaging system Open Access

Yanxiu Li; Wei Zhang; Van Phuc Nguyen; Xiaobo Xia; Xueding Wang; Yannis Mantas Paulus

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 196. doi:

Increased scattering by the RPE of Abca4^-/- mice relative to WT controls measured with OCT in vivo correlates with increased fundus autofluorescence measured with SLO Open Access

Ratheesh Kumar Meleppat; SUMAN Kalyan MANNA; Gabriel Peinado; Kaitryn Ronning; Pengfei Zhang; Edward N Pugh; Robert J Zawadzki

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 197. doi:

3D visualization of angiogenesis in the mouse eye using light sheet fluorescence microscopy Open Access

Marie Darche; Morgane Belle; Stéphane Fouquet; Alain Chédotal; Ilaria Cascone; Michel Paques

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 198. doi:

Investigating Retinal Changes in a Mouse Model of Alzheimer’s Disease using OCT Open Access

Bernhard Baumann; Danielle J. Harper; Antonia Lichtenegger; Martina Muck; Conrad W. Merkle; Johanna Gesperger; Tanja Himmel; Adelheid Woehrer; Martin Glösmann; Marco Augustin

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 199. doi:

Quantification of fluorescein leakage induced by DL-2-aminoadipic acid in an experimental model of chronic neovascular leakage Open Access

Robin J Goody; Anish Kurian; Akeem Browne; Eleanor Demmons; Darnel Allen; Chintan Patel; Wenzheng Hu; Matthew S Lawrence

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 200. doi:

OCT in Neonate Monkeys With and Without Maternal Zika Virus Exposure Open Access

Carol A Rasmussen; Seth Eaton; Nathan Diers; Peter Cueno; Emma L Mohr; David H O’Connor; Alexander W Katz; Michelle Schotzko; Christopher J Murphy; Yijun Huang; T Michael Nork

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 201. doi:

Assessment of the nonhuman primate macula across the lifespan: Thickness of retinal layers measured with sdOCT Open Access

Lauren Renner; Lily Sam; Martha Neuringer; Trevor J McGill

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 202. doi:

Characterization of the Royal College of Surgeon’s Rat Model Endpoints for Use in Preclinical Ophthalmic Studies Open Access

Justin Prater; Vicky Peele; David Culp; Brian C Gilger

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 203. doi:

Comparison of amyloid deposits in retinas of cognitively impaired and cognitively normal beagles Open Access

Laura Emptage; Melanie C W Campbell; Rachel Redekop; Erik Mason; Monika Kitor; Michael Hamel

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 204. doi:

Quantitative analysis of retinal structure and function in two chromosomally altered mouse models of Down syndrome Open Access

Alberto Costa; Daniella B Victorino; Jonah J Scott-McKean

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 205. doi:

Classification of Fluorophore Hyperspectral Signatures in Canine Best Disease Open Access

Jacob Rosenbloom; Yuehong Tong; Taariq Mohammed; Nayanika Challa; R Theodore Smith

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 206. doi:

Changes in visual function and visual pathway in experimental glaucoma induced by intracameral injection of a chemically cross-linked hydrogel Open Access

Tianmin Ren; Kevin C Chan; Yu Yu; Shuk Han Ng; Heather Mak; Wong Ying Yip; Yolandi VAN DER MERWE; Jasmine S Yung; Sayan Biswas; Xu Cao; Ying Chau; Christopher Kai-Shun Leung

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 207. doi:

OCT Camera Position Affects Apparent Eye Morphometry in Tree Shrews (Tupaia belangeri) Open Access

Preston Alexander Fuchs; Mustapha El Hamdaoui; Johanna Lee Henry; Rafael Grytz; Brian C Samuels

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 208. doi:

Evaluation of foveal avascular zone and macular vessel density in unilateral amblyopia using optical coherence tomographic angiography Open Access

Atsushi Miki; Syunsuke Araki; Katsutoshi Goto; Tsutomu Yamashita; Tsuyoshi Yoneda; Kazuko Haruishi; Yoshiaki Ieki; Junichi Kiryu; Goro Maehara; Kiyoshi Yaoeda

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 209. doi:

Amblyopia and Spectacle Compliance in Children Open Access

Kailey Marshall; Matthew Wade

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 210. doi:

Improving Grating Acuity in Adult Amblyopia by Perceptual Learning Open Access

Tsz Wing Leung; Michelle Antonucci; Betty Li; Suei Cheng Wong; Kin Ho Chan; Blake Feldmar; Kenneth Duy Tran; Chea-Su Kee; Roger Li

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 211. doi:

Training under constant instead of progressively elevated interocular inhibition leads to better cooperation between the two eyes in amblyopia Open Access

Zidong Chen; Zitian Liu; Daming Deng; Junpeng Yuan; Chang-Bing Huang; Minbin Yu

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 212. doi:

Response to Patching in Amblyopic patients with and without Fusion Maldevelopment Nystagmus Open Access

Fatema Firoz Ghasia; Aasef Shaikh

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 213. doi:

Inverse occlusion, a binocularly motivated treatment for amblyopia Open Access

Jiawei Zhou; Yidong Wu; Yiya Chen; Xiaoxin Chen; Yunjie Liang; Yu Mao; Zhimo Yao; Zhifen He; Fan Lu; Jia Qu; Robert Hess

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 214. doi:

Short-term deprivation of the amblyopic eye, combined with physical exercise, promotes long-term visual recovery in young amblyopic children Open Access

Michela Fresina; Claudia Lunghi; Chiara Fariselli; Alessandro Sale; Maria Concetta Morrone; Emilio C Campos

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 215. doi:

Comparing the effect of patching therapy with gaming for amblyopia Open Access

Aveen Kadhum; Emily T.C. Tan; Gerdien Holtslag; Huibert Jan Simonsz; Sjoukje E Loudon

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 216. doi:

Contribution of monocular patching of the amblyopic eye prior to dichoptic movie viewing for the treatment of amblyopia beyond the critical period Open Access

Lauren Sauvan; Natacha Stolowy; Danièle Denis; Frédéric Matonti; Frédéric Chavane; Robert Hess; Alexandre Reynaud

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 217. doi:

Binocular treatment for amblyopia in adults and children with low-pass filtering when occlusion therapy fails Open Access

Cindy Ho; Yousef M Shahin; Henry Reis; Stefanie Grenier; Deborah Giaschi

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 218. doi:

Functional Visual Acuity in patients with successfully treated anisometropic amblyopia Open Access

Ayaka Fujita; Sujin Hoshi; Takahiro Hiraoka; Atsuko Kato; Tomoya Murakami; Tetsuro Oshika

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 219. doi:

Preferred Fixation with the Hyperopic Eye In Children With Anisometropic Amblyopia Open Access

Nitza Goldenberg-Cohen; Amir Sternfeld; Raphaella Segal; Michael Altman

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 220. doi:

Visuomotor performance on precision grasping and aiming tasks in school-age children with abnormal binocular vision Open Access

Ewa Niechwiej-Szwedo; Glenda Thai; Lisa Christian

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 221. doi:

Abnormal monocular and dichoptic temporal synchrony in adults with Amblyopia Open Access

Chunwen Tao; Yidong Wu; Jiawei Zhou; Pi-chun Huang

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 222. doi:

Objective Blur Detection Thresholds in Amblyopic and Fellow Eyes of Children with Amblyopia Open Access

Alyssa M Gehring; Ana Juric; Isabel A. Ricker; Tawna L Roberts

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 223. doi:

Interocular suppression of form but not motion in dichoptic plaids Open Access

Amy Chow; Andrew Ernest Silva; Ben Thompson

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 224. doi:

Monocular Retinal Blockade (Pharmacological Occlusion Therapy) in Macaque Monkey: Spatial-Sweep Visually-Evoked Potential Visual Acuity, Relative Afferent Pupillary Defect, and Optokineti... Open Access

Paul E Foeller; Lawrence Tychsen

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 225. doi:

Refractive Adaptation Selectively Changes Magnocellular Pathway in Anisometropic Amblyopia Open Access

Liu Zitian; Zidong Chen; Daming Deng; Minbin Yu

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 227. doi:

'Restraining the over-achiever' in incomitant strabismus: Scott's resect-recess procedure re-visited Open Access

Sharon Armarnik; Sheetal Shirke; Elham AlQahtani; Christy Giligson; Vaishali Mehta; CHRISTOPHER John LYONS

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 228. doi:

Quantitative measurement of retinal vascular diameter changes after strabismus surgery Open Access

Jinqiong Zhou; Jing Fu; Jipeng Li; Xiaozhen Wang; Wenying Wang; Bowen Zhao; Meng Qi

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 229. doi:

Surgical outcomes following resection-recession versus plication-recession in unilateral surgery for children with intermittent exotropia Open Access

Haeng Jin Lee; Seong-Joon Kim

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 230. doi:

The influence of preoperative ocular misalignment on anatomic outcomes in patients undergoing surgical re-alignment for exotropia. Open Access

Daniel Oh; Daniel Maidana; In Ae Jung; Majid Roubach; Nathalie F Azar; Cem Mocan

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 231. doi:

Maximal horizontal rectus recession-resection procedure for complete six nerve palsy Open Access

zhonghao wang; Jianhua Yan

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 233. doi:

Surgical management of strabismus in patients with orbital fractures Open Access

Jianhua Yan; Qing xia; zhonghao wang

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 235. doi:

The effect of Inferior oblique weakening procedure on the resolution of initial overcorrection in exotropia surgery Open Access

Hee-Young Choi; HYESHIN JEON

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 236. doi:

Long-term results of slanted recession of bilateral lateral rectus muscle for intermittent exotropia with convergence insufficiency Open Access

Ji Min Kwon; Jung Min Park; Soo Jung Lee

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 237. doi:

What changes do patients report after strabismus surgery for planned psychosocial benefit? Open Access

Gemma Arblaster; Helen Davis; David Buckley; Sarah Barnes

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 238. doi:

The Effect of Strabismus Surgery on Vision Related Quality of Life Open Access

Sinthu Ranjan; Kimberly Estes; Rebecca Parrish; James Sinacore; Patricia Mumby; James F McDonnell

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 239. doi:

The Value of Surgical Realignment in Restoration of Near Stereoacuity in Pediatric Patients with Exotropia Open Access

Judy Chen; Daniel Maidana; Inae Jang; Majid Rouhbakhshzaeri; Nathalie F Azar; Cem Mocan

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 240. doi:

Satellite Cell Activity in Extraocular Muscle after Recession and Resection Open Access

Suk-Gyu Ha; Jin-Hwan Park; Seung-Hyun Kim

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 241. doi:

Visual impairment in patients with giant cell arteritis treated with tocilizumab in real-world clinical practice Open Access

Ivo Stoilov; Timothy J. McCulley; Jinglan Pei; Paris N. Sidiropoulos; Christine Birchwood; Jennie Best; John H. Stone; Sebastian Unizony

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 242. doi:

Systemic anti- IL6R antibody administration limits infiltrating leukocytes in pericyte depletion model in mice. Open Access

Eunice Cheung; Jingtai Cao; Carmelo Romano

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 243. doi:

A Cell Penetrating Peptide from Type I Interferon Protects Mice Against Experimental Autoimmune Uveitis Open Access

Alfred S Lewin; Chulbul M Ahmed; Howard M Johnson

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 244. doi:

Incidence of Polybacterial Infections in Three Bacterial Conjunctivitis Studies and Outcomes with Besifloxacin Ophthalmic Suspension 0.6% Open Access

Joseph M Blondeau; Christine M Sanfilippo; Heleen H DeCory

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 245. doi:

Antibiotic Resistance Among Ocular Pathogens – An Update from the 2018 ARMOR Study Open Access

Christine M Sanfilippo; Heleen H DeCory; Penny A Asbell

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 246. doi:

Comparison of toxicities of moxifloxacin, cefuroxime, and vancomycin on retinal vascular endothelial cells and pericytes Open Access

Hitomi Miyake; Fumie Ehara; Dai Miyazaki; Yumiko Shimizu; Yoshitsugu Inoue

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 248. doi:

HL036 Ophthalmic Solution, a Topical TNF-α Inhibitor, Significantly Improves Signs and Symptoms of Dry Eye in a Phase 2 Clinical Trial (VELOS-1) Open Access

Minjae Shin; Hyeakyung Ahn; Edward Bernton; Joo Hyun Chae; Seung Kook Park; Sunmi Park; Gail Torkildsen; George W Ousler

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 249. doi:

Ocular Pharmacokinetics of a Novel Class of Selective Multi-Kinase Inhibitors with Anti-Inflammatory Potential Open Access

Kevin Carbajal; Karen Crews; Kyle Vick; Briana E Foley; Jindong Ding; Angie Glendenning; Meredith Weksler; Cynthia L Lichorowic; Jill Sturdivant; Mitchell A. deLong; Eric C Carlson; Cheng-Wen Lin

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 250. doi:

Proportion of subjects achieving zero-trace anterior chamber inflammation with loteprednol etabonate (submicron) gel 0.38% following cataract surgery: Integrated analysis of 3 pivotal tri... Open Access

Joseph Martel; Raymond Fong; Megan E Cavet; Jason Vittitow

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 251. doi:

Topical tacrolimus use in inflammatory ocular surface diseases Open Access

Kelley Bohm; Ali R Djalilian

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 252. doi:

Chemical Landscape Analysis in Drug Discovery: Ophthalmic Fluoroquinolones Open Access

Anne Marie Clark; Christopher Baddeley; Matthew McBride

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 253. doi:

Novel blockers of the L-VGCC play a protective role in microglia-related ocular inflammation and angiogenesis disorders Open Access

Madhu Sudhana Saddala; Anton Lennikov; Anthony Mukwaya; Hu Huang

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 254. doi:

Co-culture with corneal epithelial cells decreases transformation of tenon`s capsule fibroblasts into myofibroblasts by benzalkonium chloride. Open Access

Chiemi Yamashiro; Kazuhiro Tokuda; Yuka Kobayashi; Makoto Hatano; Masaaki Kobayashi; Sho-Hei Uchi; Shinichiro Teranishi; Kazuhiro Kimura

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 255. doi:

Systemic and intraocular administration of the liposomal formulation of the cyclic GMP analogue CN03: An exploratory safety and tolerability study in non-human primates Open Access

Francois Paquet-Durand; Tobias Peters; Pieter Gaillard; Nicolaas Schipper; Torsten Strasser; Frank Schwede; Valeria Marigo; Per A R Ekstrom; Christer Säfholm

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 257. doi:

Regulation of Cataractogenesis in Cultured Bovine Lenses by ATB 337 Open Access

Catherine A Opere; Leonce N Maffofou N; Segewkal Heruye; Neetu J Singh; Ya Fatou Njie-Mbye; Sunny Ohia

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 258. doi:

Low Visual Pathway Alterations and Neurological Toxic Effects after Acute Mercury Poisoning in Zinc Manufacturer Workers Open Access

Salvador Pastor; Yrbani Lantigua; ROSA COCO; Itziar Fernandez; Antonio Dueñas-Laita; JOSE LUIS Pérez-Castrillon; Jose Carlos Pastor

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 259. doi:

Case Report: Severe Bilateral Visual Loss after Taking Overdose of Praziquantel and Triclabendazole Open Access

Ya Ma; Xiaoyan Peng

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 260. doi:

Polyelectrolyte multilayer coating for delivery of IL-4 from contact lenses for dry eye disease Open Access

Vishal Jhanji; Alexis Nolfi; Mangesh Kulkarni; Bryan Brown

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 262. doi:

Discriminant Proteomic Analysis of Dry Eye Syndrome and Glaucoma: Deciphering the Protein Code Underlying the Double Trouble Open Access

Natarajan Perumal; Caroline Manicam; Alexandra Tschäbunin; Maya Scieranski; Aline Ratcliffe; Laura Gronbach; Norbert Pfeiffer; Franz H Grus

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 263. doi:

Effect of parthenocissus tricuspidata extract living on pine in pre-clinical model of dry eye disease Open Access

Kyong Jin Cho; Jeongyun Kim; Zu Un Kim

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 264. doi:

Changes in tears and ocular structures involved in tear film formation in chemotherapy-induced polyneuropathy in mice Open Access

Jessica Welss; Nichapa Phunchago; Marco Sisignano; Natarajan Perumal; Franz Grus; Jessica Feldt; Elke Lütjen-Drecoll; Friedrich P Paulsen

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 265. doi:

The Effect of Comprising Natural Extracts in Experimental Dry Eye Rat Model Open Access

Soo Youn Choi; Youngsub Eom; Jee Yong Kim; Dong Hoon Jang; Jong Suk Song; Sehyun Baek; Hyo Myung Kim

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 266. doi:

Up-regulating autophagy with trehalose: a contribution to osmoprotective properties ? Open Access

Marc Labetoulle; Eva Hernandez; Oscar Haigh; Antoine Rousseau; Audrey Esclatine

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 267. doi:

Expression and Role of Nucleotide-binding Oligomerization Domain 2 (NOD2) in the Ocular Surface of Murine Dry Eye Open Access

Ying Li; Ru Jun Jin; Lan Li; HYEON JEONG YOON; In-Cheon You; Kyung Chul Yoon

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 268. doi:

Inhibitory Effect of Topical Thymosin beta 4 against Ocular Surface Inflammation in a Mouse Model of Experimental Dry Eye Open Access

Rujun Jin; Ying Li; Lan Li; HYEON JEONG YOON; In-Cheon You; Kyung Chul Yoon

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 269. doi:

NRF2 activator RS9 protects corneal epithelium from cell damage in dry eye models Open Access

Yuka Matsuda; Mamiko Machida; Yasuhiro Nakagami; Takeshi Nakajima; Mitsuyoshi Azuma

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 270. doi:

Age-associated changes in T effector and regulatory T cells Open Access

Cintia S De Paiva; Humberto Hernandez; Rodrigo G. de Souza; Zhiyuan Yu; Fang Bian

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 271. doi:

Sjögren-Syndrome Microbiota Colonization in Germ-Free Mice induces Antigen-Presenting Cell Activation and Production of IL-12 Open Access

Laura Schaefer; Claudia M Trujillo-Vargas; Stephen C Pflugfelder; Robert A Britton; Cintia S De Paiva

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 272. doi:

Application of a Cannabinoid-Receptor Agonist in a Mouse Model of Desiccating Stress Open Access

Philipp Steven; Daniela Heß; Horstmann Jens; Frank M Dautzenberg; Michael E Stern; Uta Gehlsen

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 273. doi:

Comparison of inflammatory gene networks in dry eye between human and mouse Open Access

Karima Kessal; Philippe Daull; Laurence Feraille; Nicolas Cimbolini; Hong Liang; Mylene Docquier; Stefano Barabino; Stephane Melik Parsadaniantz; Jean-Sebastien Garrigue; CRISTOPHE BAUDOUIN; Françoise Baudouin

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 274. doi:

Low humidity plus anti-cholinergic-induced dry eye skews toward a Th1 response Open Access

Zhiyuan Yu; Jehan Alam; Rodrigo G. de Souza; Cintia S De Paiva; Stephen C Pflugfelder

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 275. doi:

Selective serotonin reuptake inhibitorsaggravate depression- associated dry eyevia activating the NF-κB pathway Open Access

Xiaozhao Zhang; Yue Yin; Lan Gong

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 277. doi:

Analysis of CD4+ T cell populations in male NOD mice highlights the potential of local administration of cyclosporine A in the treatment of Sjögren’s syndrome Open Access

Hao Guo; John Andrew MacKay; Sarah F Hamm-Alvarez

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 279. doi:

Identification of Botanical Extracts with PPARγ Receptor Activity for Improving Meibomian Gland Health and Function. Open Access

James V Jester; Sun Woong Kim; Yilu Xie; Dawna Venzon; Becky L. Bender; Mary A. Murray; John F. Rebhun; Rohit P. Dugar; Kevin W. Gellenbeck; Kelly M. Glynn

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 280. doi:

Eicosapentaenoic acid activates PPARγ signaling leading to lipid synthesis and autophagy in hMGEC Open Access

Sun Woong Kim; Xie Yilu; Donald Brown; James V Jester

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 281. doi:

Efficient Delivery of a Hydrophobic PPAR Agonist OS300 via a Nanostructured Delivery System, for the Treatment of Meibomian Gland Dysfunction Open Access

Koushik Barman; Swathi Amere; Kevin Ward; Shikha P Barman

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 282. doi:

Glutathione Supplementation May Enhance Buthionine Sulfoximine-Induced Cell Death in Immortalized Human Meibomian Gland Epithelial Cells Open Access

William Ngo; Jason J Nichols

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 284. doi:

Pharmacokinetics of OTX-CSI, a Sustained Release Cyclosporine Intracanalicular Insert in Beagles Open Access

Andrew Vanslette; Charles D Blizzard; Paul Haberman; Julia Tomaszewski; Courtney Rosales; Jamie L Metzinger; Michael H Goldstein; Arthur Driscoll

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 285. doi:

High content imaging assay for detection of immunological synapse inhibition of ICAM-1/LFA-1 binding with lifitegrast Open Access

Anneli Savinainen; Anthony Essex; Galen Carey; Geoff Grandjean

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 286. doi:

Enhanced Ocular Delivery Using Biocompatible Nanomaterials Open Access

David L Kent; Gautam Behl; Sangeeta Kumari; Niall O' Reilly; Peter McLoughlin; Orla O' Donovan; Laurence Fitzhenry

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 287. doi:

Protective effects of Risuteganib® against inflammation and oxidative stress on a Dry Eye Disease experimental model on C57BL / 6J mice Open Access

Hugo Quiroz-Mercado; LUIS F HERNANDEZ; Ivan Ramos-Martínez; Ruben Zamora-Alvarado; Lenin Ochoa-de la Paz; Anri Pérez-Nakano; Roberto Gonzalez-Salinas

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 288. doi:

Effects of topical dry eye treatment on anxiety-related behavior in a mouse dry eye model Open Access

Takashi Kojima; Sayaka Omura; Taeko Nagata; Cem Simsek; Murat Dogru; Kazuo Tsubota

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 289. doi:

Therapeutic effect of STAT3 inhibition on experimental murine dry eye. Open Access

MINGLI QU; Xia Qi; Qian Wang; Lei Wan; Qingjun Zhou

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 290. doi:

Dry Eye: Efficacy evaluation of three synthetic peptides from Chondrocyte-Derived ExtraCellular Matrix (CDEM) in comparison to lifitegrast, cyclosporine A, diquafosol sodium and sodium hy... Open Access

Mark Taegon Baik; JongYoon Choi; Kyungwook Min; Laurence Feraille; Elisabeth Raymond; Elena Pierre-Paul

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 291. doi:

Efficacy of preservative-free cyclosporine emulsion eye drops in a mouse model of dry eye Open Access

Philippe Daull; Takashi Nagano; Shinji Okada; Emilie Gros; Laurence Feraille; Jean-Sebastien Garrigue

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 292. doi:

The discovery of novel LFA-1 antagonist VVN001 to treat Dry Eye Disease (DED) Open Access

Yong Li; Erning Xia; wang shen

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 293. doi:

EVALUATION OF THE DRY EYE IN THE EXPERIMENTAL MODEL OF SJOGREN SYNDROME (SJS) Open Access

Lucimeire Nova Carvalho; Priscila Cardoso Cristovam; Alex Nasare; Larissa Rigobeli Rosa; Jose Alvaro Pereira Gomes

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 294. doi:

Lacrimal gland acinar TRAIL (CD253) expression is essential for inhibiting bone marrow-derived CD45+ inflammatory cell infiltration in dry eye disease Open Access

Hyung Keun Lee; Yong Woo Ji; Eunyoung Choi; Arum Yeo

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 296. doi:

Analysis of the tear MicroRNA levels in primary sjögren’s syndrome Open Access

Yu Jeong Kim; Yeji Yeon; Jaeyoung Kim; Yong Un Shin; Heeyoon Cho; Han Woong Lim; Min Ho Kang

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 297. doi:

A Newly Thermo-Responsive Artificial Tear Formulation, AT-1401: Its Retentivity and Efficacy on Ocular Surface Open Access

Mitsuyo Takashima; Moto Kimura; Takeshi Yamamura; Tomohiro Otsuka; Yuji Takahashi; Ayako Suzuki; Ayaka Yamamuro; Saki Watanabe; Kazunao Masubuchi; Reijiro Arakawa; Akira Naito

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 298. doi:

Subconjunctival dendrimer-cyclosporin therapy for the treatment of dry eye in a rabbit model of induced autoimmune dacryoadenitis Open Access

Hui Lin; Rishi Sharma; Siva Pramodh Kambhampati; Kannan Rangaramanujam; Samuel C Yiu

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 299. doi:

Effect of cevimeline in ocular surface of dry eye mouse model Open Access

Chae Eun Kim; Dong-Yoon Kum; Young-Joon Park; Yoonjin Lee; Byul-Nim Ahn; Jaewook Yang

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 300. doi:

The effect of an ocular surface modulator in an in vitro model of inflammatory dry eye Open Access

Stefano Barabino; Francesco Carriero; Silvia Balzaretti; Demetrio Manenti; Marisa Meloni

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 301. doi:

Mucoadhesive micelles for anterior segment ocular drug delivery Open Access

Emily Anne Hicks; Ben B Muirhead; Talena Rambarran; Naveed Yasin; Lina Liu; Frances Lasowski; Heather Sheardown

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 302. doi:

Characterization of a New Phospholipid Containing Nanoemulsion Lubricant Eye Drop for Dry Eye Open Access

Rekha Rangarajan; Howard Ketelson; Richard Do; David McCanna; Adeline Suko; Daryl Enstone; Lakshman Subbaraman; Lyndon William Jones; Anne Meyer

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 303. doi:

Effectiveness of 3% trehalose and 0.15% sodium hyaluronate eye drop in an adverse dry environment Open Access

Hamad Alzamil; Louise; Madden; Edward Ian Pearce

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 304. doi:

Effects of ALY688 on Atropine-Induced Dry Eye in Rabbits Open Access

Kathryn S Crawford; Carter Schuh; Jordan Schuh; Henry Hsu

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 305. doi:

Restoration of regulatory T cell function in dry eye disease by targeting substance P/neurokinin 1 receptor Open Access

Yukako Taketani; Thomas Dohlman; Yihe Chen; Reza Dana

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 306. doi:

SP-G, a novel surfactant protein of the ocular surface that regulates surface tension of tears and might play a role in dry eye disease Open Access

Lars Bräuer; Martin Schicht; Friedrich P Paulsen

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 307. doi:

Multivalent Lacripep Elastin-Like Polypeptide fusions initiate calcium signaling and prosecretory activity in cells of the ocular surface system Open Access

Changrim Lee; Maria Edman; Sarah F Hamm-Alvarez; John Andrew MacKay

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 308. doi:

Sub-Anticoagulant Dose Heparin Dismantles Neutrophil Extracellular Traps (NETs): Therapeutic Implementations for Dry Eye Disease (DED) Open Access

Jieun Kwon; SEUNGWON AN; Illangovan Raju; Bayasgalan Surenkhuu; Anubhav Pradeep; Christine Mun; Nour Atassi; Sandeep Jain

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 309. doi:

Ability of lifitegrast to block immunological synapse formation and downstream T cell function Open Access

Galen Carey; Louise Brackenbury; Anneli Savinainen; Sylvie Hunt

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 310. doi:

Inhibition of corneal nociceptors reduces persistent, ongoing dry eye-induced pain Open Access

Neal Mecum; Rachel Russell; Joshua Havelin; Ian Meng

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 311. doi:

Five Year Outcomes of Corneal Collagen Crosslinking: Accelerated Crosslinking Induces Less Corneal Haze and Less Continuous Corneal Flattening Compared to Conventional Crosslinking. Open Access

Naoko Kato; Kazuno Negishi; Chikako Sakai; Ikuko Toda; Takeshi Ide; Kazuo Tsubota

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 313. doi:

Exosomes and their miRNA/protein contents in Keratoconus Open Access

Rabab Sharif; Mariam Khaled; JIn-Xiong She; Yutao Liu; Dimitrios Karamichos

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 314. doi:

Corneal Response to Transepithelial Corneal Collagen Crosslinking for Keratoconus Open Access

Michael Lai; Steven Greenstein; Peter Hersh

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 315. doi:

Oxygen uptake into porcine cornea with topical administration of ozonated water Open Access

Koji Kakisu

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 316. doi:

Biomechanical Impact of Drug Formulation, Supplemental Oxygen, and UV Delivery on Epi-On CXL Open Access

Desmond Christopher Adler; Jason Hill; Cailing Liu; Phillip Deardorff; Michael Raizman; Rajesh Rajpal

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 317. doi:

Clinical Outcomes of KeraVio using Violet Light Emitting Glasses and Riboflavin for Corneal Ectasia: A Pilot Study Open Access

Hidenaga Kobashi; Hidemasa Torii; Ikuko Toda; Kazuo Tsubota

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 318. doi:

Changes in collagen structure and permeability of rat and human scleral tissue after crosslinking Open Access

Sruti S Akella; Jing Yang; Peng Guo; Yuan Miao; Cheng Zhang; Roy S Chuck

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 319. doi:

Ocular surface disease index and ocular thermography in keratoconus and in normal subjects Open Access

Orsolya Németh; Sabine Lepper; Georgia Milioti; Aladin Abdin; Berthold Seitz; Timo Eppig; Zoltan Zsolt Nagy; Achim Langenbucher; Nóra Szentmáry

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 320. doi:

Assessment of clinical parameters by ethnicity in patients with keratoconus: a multi-country study. Open Access

Srujana Sahebjada; Elsie Chan; Myra McGuinness; Christopher Hodge; Calvin C P Pang; Govindasamy Kumaramanickavel; Gerard Sutton; Mark Daniell; Paul N Baird

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 321. doi:

Altered regulation of arginine metabolism during hypoxia in keratoconus human corneal fibroblasts Open Access

Tanja Stachon; Lorenz Latta; Berthold Seitz; Nóra Szentmáry

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 323. doi:

Patient Satisfaction and Visual Function after combination Intracorneal Ring Segments and Corneal Collagen Crosslinking Open Access

Daniel Chung; Steven Greenstein; Peter Hersh

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 324. doi:

Stromal Oxygen Dynamics During High-Irradiance Epi-On Corneal Crosslinking Open Access

jason mark hill; Cailing Liu; Phillip Deardorff; Desmond Christopher Adler; Vance Thompson; Daniel Gore

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 325. doi:

Depth-resolved collagen order after in vivo rabbit corneal cross-linking Open Access

James A Germann; Eduardo Martinez-Enriquez; Carmen Martinez-Garcia; Irene E Kochevar; Susana Marcos

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 326. doi:

Impact of Eye Motion and Active vs. Passive Eye Tracking on Refractive Crosslinking Open Access

David Usher; Amit Mukherjee; Mikhail Smirnov; Jason Hill; William Eddington; Cailing Liu; Desmond Christopher Adler

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 327. doi:

Regulation of the Keratoconic in vitro phenotype through Integrated stress response stimulation Open Access

James William Foster; Uri Soiberman; Michelle Lu; Ahmed Shehata; Tempest Young; Yassine Daoud; Albert S Jun

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 328. doi:

Depth-dependent analysis of contact lens-assisted corneal cross-linking by Brillouin microscopy Open Access

Hongyuan Zhang; ANDRE LUIS PICCININI; mehdi roozbahani; Oren Golan; Giuliano Scarcelli; James Bradley Randleman

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 329. doi:

Depth dependent measurements of the concentration of riboflavin to make the crosslinking (CXL) treatment safer Open Access

Maximilian Franke; Timm Landes; Theo G. Seiler; Alexander Heisterkamp; Dag Heinemann; Tammo Ripken

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 330. doi:

In-vivo evaluation of corneal collagen fibrils pattern to detect keratoconus Open Access

Vito Romano; Dr. Davide Borroni; Brendan Geraghty; Eugenio Lipari; Alessandra Sborgia; Yalin Zheng; Stephen B Kaye; Bryan Williams

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 331. doi:

Progression predictive factors of keratoconus after accelerated crosslinking (A CXL) Open Access

DA COSTA Marie; SOT Maxime; Justine Menet; christophe goetz; Nadia Ouamara; Zaidi Mohamed; Louis Lhuillier; Jean-Marc Perone

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 332. doi:

Gene expression in the corneal epithelium of progressive keratoconus patients Open Access

Uri Soiberman

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 333. doi:

In-vivo and in-vitro corneal epithelial and stromal thickness in Keratoconus Open Access

Nicole Hallett; Vinod Kumar Maseedupally; Maria Markoulli; Niroshan Jeyakumar; Christopher Hodge; Gerard Sutton; Jingjing You

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 334. doi:

Profile of inflammatory factors in patients with keratoconus after penetrating keratoplasty Open Access

Daniel Robles Yeme; Elisa Alegría-Gómez; Atzín Robles-Contreras; Oscar Baca Lozada; Oscar Fernandez Vizcaya; Cristina Pacheco Del Valle; Regina Velasco-Ramos; Alejandro Babayan Sosa; Eleuterio Ferrer-Cobos

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 335. doi:

CORNEAL CROSSLINKING EFFECTS ON TEAR INFLAMMATORY MEDIATORS IN PATIENTS WITH KERATOCONUS Open Access

Dahana Lucia Thalia Lucia Thalia Mendoza-Garcia; Cristina Pacheco Del Valle; Atzín Robles-Contreras; Oscar Baca Lozada; Oscar Fernandez Vizcaya; Regina Velasco-Ramos; Elisa Alegría-Gómez; Alejandro Babayan Sosa; Eleuterio Ferrer-Cobos

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 336. doi:

Optimizing time in crosslinking: scleral lens based riboflavin impregnation. A pilot study Open Access

Natalia Paulina Quiroz-Casian; Omar Santana-Cruz; Alejandro Navas; Arturo J Ramirez-Miranda; Enrique O Graue-Hernandez

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 337. doi:

Spectrum of Binocular Vision Function in Keratoconus Patients Open Access

Prema Padmanabhan; Sushmitha Dandapani; Jameel Rizwana Hussaindeen

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 338. doi:

Ten year results after corneal collagen crosslinking with riboflavin and UV-A irradiation (CXL) for keratoconus – when to repeat CXL? Open Access

Franziska Seifert; Franziska Seufert; Dorothee Hommes; Gunda Kann; Luisa Thederan; Jost Hillenkamp; Daniel Kampik

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 339. doi:

Improving precision for determining change in patients with keratoconus Open Access

Carlos Rocha de lossada; Matthias Brunner; Dr. Davide Borroni; Esmaeil Arbabi; Stephen B Kaye; Vito Romano; Gabriela Czanner

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 340. doi:

Main corneal tomographic findings, tear film cytokine profile and proteomic analysis in keratoconus families Open Access

Daniel Borges; Bruna Duarte; Heloisa Balan Assalin; Dioze Guadagnini; Mario Jose Abdalla Saad; Carlos Eduardo Leite Arieta; Monica Alves

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 341. doi:

In vivo Brillouin microscopy in crosslinked Keratoconus corneas Open Access

Theo G G. Seiler; Peng Shao; Amira M Eltony; Theo Seiler; Seok-Hyun Yun

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 342. doi:

Riboflavin Concentrations at the Endothelium during Corneal Crosslinking (CXL) Open Access

Beatrice E Frueh; Ana Batista; Karsten Koenig; Theo G G. Seiler

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 343. doi:

Higher Order Aberration Measurement Comparison Between Scheimpflug and Dual Scheimpflug/Placido Technology in Normal and Keratoconic Eyes Open Access

Claudia Elena Perez Straziota; ANDRE LUIS PICCININI; Oren Golan; Emilio Almeida Torres-Netto; Farhad Hafezi; James Bradley Randleman

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 344. doi:

Safety and efficacy of accelerated cornea cross-linking to arrest progression of corneal ectasia in a tertiary referral center in the UK Open Access

Borja Salvador Culla; Afsara Ahmmed; Nicola Roper; Julie Mulroy; David Tabibian; Francisco Figueiredo

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 345. doi:

Barbatimão (Stryphnodendron adstringens) extract as a potent corneal crosslinking agent: Laboratory characterization by differential scanning calorimetry (DSC) Open Access

Paulo Schor; Aline Reis; Taleesa Carvalho; Aline Marquini; Andreia Morandim-Giannetti; Patricia Alessandra Bersanetti

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 346. doi:

Early evidence of visual and topographic improvements following cross-linking procedure in eyes with keratoconus Open Access

Dian Yu; Jay M Lustbader

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 347. doi:

Comparison of the variability of Scheimpflug imaging measurements between normal eyes, progressive and no-progressive keratoconus eyes at 1 year of follow up. Open Access

Raúl Alberto Zúñiga Iracheta; Jorge Camargo Acuña; MAYTHÉ ESTEPHANÍA CAMINO QUEZADA; Carmen Maldonado; José Chauca; Katia Ruiz-Montenegro Villa; Luis Izquierdo; Maria A Henriquez

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 348. doi:

Delayed re-epithelialization after epithelium-off crosslinking: associated factors and impact on keratoconus progression Open Access

Chiara Bonzano; Donatella Musetti; Riccardo Scotto; Marta Sturloni; Carlo Alberto Cutolo; Carlo Enrico Traverso

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 349. doi:

OCT-Guided Laser Custom Corneal Collagen Cross-linking in Keratoconus Open Access

Yan Li; Omkar C Thaware; Winston Chamberlain; Afshan Nanji; John Clements; David Huang

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 350. doi:

Correlation between basal keratometric readings and the keratometric change at 12 months in two pulsed accelerated crosslinking protocols Open Access

Julio C Hernandez; Raul Ruiz; Denise Loya; Jorge E. Valdez-Garcia

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 351. doi:

Keratoconus: New insights in the underlying pathomechanism Open Access

Uwe Hansen; Melanie Timmen; Martin Goette; Richard Stange; Thomas Pap; Nicole Eter; Maged Alnawaiseh

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 353. doi:

Evaluation of a topical corneal cross-linking solution using sodium hydroxymethylglycinate by intravital confocal microscopy in the Dutch-belted rabbit: a follow up report on keratocyte m... Open Access

David C Paik; Mariya Zyablitskaya; Anna Takaoka; Jaya R. Mehta; Estee Hong; Sara Fallahi; Leejee Suh; Takayuki Nagasaki; Stephen L. Trokel

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 354. doi:

Small PEDF-derived peptides mitigate choroidal neovascularization Open Access

Jack Henkin; Ignacio Melgar-Asensio; Soesiawati R. Darjatmoko; Shoujian Wang; Christine M. Sorenson; Daniel M Albert; Reshma Bhowmick; Olga Volpert; Nader Sheibani

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 355. doi:

Short Term Effects of Carbidopa-Levodopa in Neovascular AMD Open Access

Brennan Michael Boyd; Timothy Fagan; Anna G. Figueroa; Brian S McKay; Robert W Snyder

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 356. doi:

Kaempferol protects retinal function in a mouse model of light-induced retinal damage Open Access

Jonathan Noguchi; Zhiqun Tan; James F McDonnell; Jay Ira Perlman; Ping Bu

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 357. doi:

Effects of the Mitochondria-Targeted Drug Elamipretide on Leakage-Independent Vision Loss in Fellow Eyes with Neovascular AMD in the ReCLAIM Study Open Access

Priyatham S Mettu; Michael John Allingham; Scott W Cousins

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 358. doi:

Does Brimonidine DDS Reduce the Geographic Atrophy Lesion Perimeter Hyperautofluorescence Over Time? Open Access

Amber Lewis; Ilona Kravtsova; Kevin Kerr; Yan Li; Werner Schmidt; Francisco López

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 359. doi:

Robust Generation of Photoreceptor Precursors from Human Pluripotent Stem Cells Using a Scalable 3D Bioreactor System Open Access

Qiang Feng; Christopher Chen; Jingping Zhang; Shi-Jiang Lu

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 360. doi:

Elamipretide, a Mitochondrial-Targeted Drug, for the Treatment of Vision Loss in Dry AMD with High Risk Drusen: Results of the Phase 1 ReCLAIM Study Open Access

Michael John Allingham; Priyatham S Mettu; Scott W Cousins

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 361. doi:

Triptolide inhibits experimental choroidal neovascularization in mice by modulating focal inflammatory microenvironment through macrophages Open Access

Kunbei Lai; Yajun Gong; Longhui Li; Chuangxin Huang; Fabao Xu; Chenjin Jin

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 362. doi:

The Use of Photodynamic Therapy in Exudative Age Related Macular Degeneration for Subretinal Fluid Refractory to Anti-VEGF Treatment Open Access

Michelle Peng; Robert Johnson

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 363. doi:

The local and systemic effects following subthreshold nanosecond laser treatment to the posterior retina Open Access

Quan Findlay; Andrew Ian Jobling; Kirstan Anne Vessey; Ursula Greferath; Pavan Avula; Ben Gu; Robyn H Guymer; Erica L Fletcher

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 364. doi:

Stabilization and supporting blood vessel growth as a new concept to treat wet AMD Open Access

Sylvie Julien; Alexander Tschulakow; Harsh Thakkar; Shan Liu; Barbara Illing; Ulrich Schraermeyer

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 366. doi:

IDB0062, a dual targeting protein for enhanced anti-angiogenic effect for several ocular diseases. Open Access

Seongbeom Kim; Seokwoo Yang; Kihong Min; Bomin Kim; Jeong Hun Kim; Hyuksang Kwon; SungKu Choi

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 367. doi:

P2X7 antagonist attenuates retinal inflammation and neovascularization induced by oxidized low density lipoprotein in mice Open Access

Mingzhu Yang

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 368. doi:

Inhibition of Microfibrillar-associated Protein 4 as a Potential Therapy Targeting Choroidal Neovascularisation in Age-related Macular Degeneration Open Access

Andew Benest; Amy P Lynch; Anders Schlosser; Uffe Holmskov; Grith Lykke Sorensen; David O Bates

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 369. doi:

Vitrectomy With or Without Drainage of Subretinal Hemorrhage for Breakthrough Vitreous Hemorrhage Secondary to Polypoidal Choroidal Vasculopathy Open Access

PENG SUN; Feng Gu; Han Zhang; Zheli Liu

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 370. doi:

The effect of varying dosage and fluence setting of Verteporfin on choroidal vasculature in a rodent model Open Access

PENG QIN; Ian Wong

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 371. doi:

Efficacy & Tolerability of OTX-TKI, a Sustained Hydrogel Delivery System for a Tyrosine Kinase Inhibitor, in a VEGF Induced Retinal Leakage Model: 1 Year Results Open Access

Peter K Jarrett; Rami F Elhayek; Erica Kahn; Stephen Takach; Jamie L Metzinger; Michael H Goldstein

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 372. doi:

Pegylated CB2782: a Complement Factor C3-Inactivating Protease and Potential Long-Acting Treatment for Dry AMD Open Access

Eric Furfine; Anjali Rao; Sue Baker; Mary Katherine Connacher; Alexei Kazanstev; Brajesh Kumar; Grant Blouse; Marty Stanton; Matt Traylor

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 374. doi:

Taurocholic acid prevents progression of age-related macular degeneration in in vitro models Open Access

Joshua McAlister Barnett; Cassandra Warden; Milam A Brantley

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 375. doi:

Phenotypic variability in patients with CDHR1 mutations Open Access

David Andrew Terrell; Rachel M Huckfeldt; Eric A Pierce; Emily Margaret Place

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 376. doi:

ABCA4-associated disease as a model for missing heritability in autosomal recessive disorders: novel non-coding splice, cis-regulatory, structural and recurrent hypomorphic variants Open Access

Miriam Bauwens; Alex Garanto; Riccardo Sangermano; Sarah Naessens; Nicole Weisschuh; Julie De Zaeytijd; Mubeen Khan; Françoise Sadler; Susanne Kohl; Bernd Wissinger; timothy cherry; Rob W J Collin; Frans P Cremers; Bart P Leroy; Elfride De Baere

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 377. doi:

Mutations in splicing factors that cause Retinitis Pigmentosa (RP) do not affect splicing in a global manner Open Access

Revital Bronstein; Sudeep Mehrotra; Elizabeth E. Capowski; Leah Foltz; Michael H Farkas; David M Gamm; Dennis O Clegg; Eric A Pierce

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 379. doi:

Biallelic Mutations in a Novel Gene FAM*** are Associated with Inherited Retinal Dystrophies Open Access

Zhen Yii; Qingjiong Zhang

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 380. doi:

Mutations in WDR34 is a rare cause of non-syndromic autosomal recessive rod-cone dystrophy Open Access

Isabelle S Audo; Maria Solaguren-Beascoa; Kinga Bujakowska; Cécile Méjécase; Lisa Emmengger; Saddek Mohand-Said; Thierry D Leveillard; Eric A Pierce; Helene Dollfus; Jose Alain Sahel; Shomi Bhattacharya; Christina Zeitz

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 381. doi:

Analysis of Irish Inherited Retinal Degeneration Patients with ABCA4 Gene Mutations. Open Access

Niamh Wynne; Karen Collins; Hilary Dempsey; Kirk Stephenson; David J Keegan; Giuliana Silvestri; Adrian Dockery; Gwyneth Jane Farrar; Paul F Kenna

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 383. doi:

Mutational analysis of the PABPN1 gene in oculopharyngeal muscular dystrophy Open Access

Cristina Plata; Héctor Pérez; Humberto López; Gerardo Graue Moreno; Mirena Astiazaran

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 384. doi:

Whole exome sequencing-based copy number variant detection in inherited retinal disease Open Access

Frauke Coppieters; Stijn Van de Sompele; Kristof Van Schil; Thalia Van Laethem; Rani Six; Sarah De Jaegere; Francoise Meire; Meindert De Vries; Irina Balikova; Julie De Zaeytijd; Bart P Leroy; Toon Rosseel; Elfride De Baere

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 385. doi:

NEI Ocular Proteome Database: A Description of Inherited Eye Disease Proteins and Their Stability Changes by a Computational Global Mutagenesis. Open Access

Claudia Kassouf; Caitlyn McCafferty; Yuri V Sergeev; Francisca Wood Ortiz

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 386. doi:

Novel mutations associated with keratoconus found by a bioinformatic approach Open Access

Daniela Gomez-Elizondo; Mariana Lopez-Martinez; Judith Zavala; Jorge E. Valdez-García; Victor Treviño

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 387. doi:

Reduced expression of “normal” ABCA4 alleles in iPS-derived RPE cells from Stargardt Disease patients Open Access

Anna Matynia; Saravanan Karumbayaram; Samuel Strom; Jane Hu; Nermin Kady; Roxana A Radu; Michael B Gorin

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 388. doi:

The number of RPGR cases remains under-represented Open Access

Elise Heon; Anjali Vig; Erika Tavares; Ajoy Vincent

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 389. doi:

Improving diagnostic yield in a large inherited retinal dystrophy cohort with high-throughput, NGS-based CNV calling -- a clinical evaluation of detection criteria and limitations Open Access

Nicholas K Wang; Jie Duan; Christa Kohnert; Gregory Goh; Wei Zhou; John (P-W) Chiang

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 390. doi:

High myopia with alopecia areata in cranial midline：COL18A1 and LAMA1 mutant Open Access

Panfeng Wang; Xueshan Xiao; Shiqiang Li; Xiaoyun Jia; Qingjiong Zhang

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 391. doi:

Testing for North Carolina Macular Dystrophy (NCMD) Variations Open Access

Markus N Preising; Marc Platschek; Birgit Lorenz

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 395. doi:

CAPN5 genetic inactivation phenotype supports therapeutic inhibition trials Open Access

Katherine Wert; Susanne F. Koch; Gabriel Velez; Chun-Wei Hsu; MaryAnn Mahajan; Alexander G. Bassuk; Stephen H. Tsang; Vinit B Mahajan

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 396. doi:

WITHDRAWN_Genetic variations in Bestrophin-1 and Related Clinical Findings between Chinese patients with juvenile-onset and adult-onset best vitelliform macular dystrophy Open Access

Ying Lin; Xinhua Huang; Lin Lu

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 397. doi:

Report of five families with autosomal recessive Bestrophinopathies (ARB) Open Access

Habibi Imen; Yosra Falfoul; Margarita G. Todorova; Stefan Wyrsch; Daniel F Schorderet; Leila El Matri

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 398. doi:

CSDE1 haploinsufficiency associated with ocular developmental abnormalities in human and zebrafish Open Access

Sairah Yousaf; James Liu; Mariya R Ahmed; Robert Hufnagel

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 399. doi:

Prevalence and genetic characteristics of RPE65-associated retinal disease Open Access

Tero-Pekka Alastalo; Kati Kämpjärvi; Lucia Guidugli; Johanna Känsäkoski; Kirsty Wells; Hanna Västinsalo; Laura Sarantaus; Pertteli Salmenperä; Samuel Myllykangas; Eeva-Marja Kaarina Sankila; Juha Koskenvuo; Sari Tuupanen

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 400. doi:

Genetic basis of inherited retinal disease in a UK cohort of over 2900 families Open Access

Omar Abdul Rahman Mahroo; NIKOLAS PONTIKOS; Gavin Arno; Rola Ba-Abbad; Samantha Malka; Genevieve Wright; Monica Armengol; Menachem Katz; Anthony Moore; Michel Michaelides; Andrew Webster

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 401. doi:

Pathogenicity of five new variants of BEST-1 gene among an Italian cohort: a multicentric study Open Access

Giulia Delledonne; Anna Paola Salvetti; Marta Oldani; Paolo Maltese; Matteo Bertelli; Lucia Ziccardi; Benedetto Falsini; Vladimir Frecer; Giovanni Staurenghi

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 402. doi:

Detection of clinically relevant genetic variants in nanophthalmos by whole genome sequencing Open Access

Zhigang Fan; Congcong Guo; Zhenni Zhao; Denghui Chen; Shuxiang He; Nannan Sun; Zhongwen Li; Jiafan Liu; Dandan Zhang; Jiamin Zhang; Jianlong Li; Miao Zhang; Shihui Yu; Weiwei Zhao; Jingxing Liu; Xiaoling Zhang

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 403. doi:

Clinical and genetic characterization of Pseudoxanthoma Elasticum patients Open Access

Iyar Sheps; Chen Weiner; Nadav Shoshany; Eran Pras

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 404. doi:

TTR mutations and clinical characteristics of patients with vitreous amyloidosis Open Access

Xiaohui Zhang; Ke Xu; Xiaolin Xu; Yang Li

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 405. doi:

Investigating the Effect of a PEX6 Mutation on Peroxisome Structure and Function Open Access

Matthew David Benson; Ian M MacDonald

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 406. doi:

Worldwide Carrier Frequency Analysis of Mutations Causing Autosomal Recessive Inherited Retinal Diseases Open Access

Mor Hanany; Segev Meyer; Carlo Rivolta; Dror Sharon

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 407. doi:

Retinal phenotypic characterization of a Brazilian cohort of patients with homozygous ABCA4 alleles Open Access

Fernanda Belga Ottoni Porto; Shirley AM Sampaio; Simões T Renata; Rui Chen; John (P-W) Chiang

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 408. doi:

Genome-wide screening of gene-gene interaction between HLA risk factors and other genes in Behçet’s disease Open Access

Akira Meguro; Takahiro Yamane; Masaki Takeuchi; Masao Ota; Nobuhisa Mizuki

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 409. doi:

Novel OPA1 gene mutations in Japanese patients with optic atrophy Open Access

SHIGERU SATO; Noriyasu Hashida; Takeshi Morimoto; Kikuko Hotta; Takashi Fujikado; Kohji Nishida

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 410. doi:

The Liberfarb syndrome, a multisystem disorder including early-onset retinal degeneration, is caused by a founder mutation in the PISD gene in patients from Portugal, Brazil, and the Azor... Open Access

Virginie Gisèle Peter; Mathieu Quinodoz; Jorge Pinto-Basto; Sergio De Sousa; Silvio Alessandro Di Gioia; Gabriela Soares; Gabriela Ferraz Leal; Eduardo Silva; Elizabeth Engle; Noriko Miyake; Naomichi Matsumoto; Sheila Unger; Frederic Shapiro; Belinda Campos-Xavier; Andrea Superti-Furga; Carlo Rivolta

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 411. doi:

A novel SVA retrotransposon insertion in CHM results in loss of REP-1 protein causing choroideremia Open Access

Kaylie Webb-Jones; alina radziwon; David G Birch; Ian M MacDonald

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 412. doi:

Non-penetrance in a family with PAX6-related autosomal dominant nystagmus Open Access

Vijay Tailor; Christopher Way; Nicholas Owen; Maria Theodorou; Mariya Moosajee

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 413. doi:

Mutation Screening of OPA1 in a cohort Chinese patients with Suspected Autosomal Dominant Optic Atrophy Open Access

YUE XIE; Ting Xiao; Ke Xu; Xiaohui Zhang; Yang Li

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 414. doi:

A CCDC51 frameshift variant as a candidate gene defect for autosomal recessive rod-cone dystrophy Open Access

Christina Zeitz; Cécile Méjécase; Saddek Mohand-Saïd; Lisa Emmengger; Audrey Schalk; Marion Neuillé; Elise Orhan; Frédéric Blond; Camille Prévot; Sandra Sandra Chantot-Bastaraud; Thierry D Leveillard; Jose Alain Sahel; Isabelle S Audo

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 415. doi:

Retina Has Significant Protective Mechanisms to Eliminate Mitochondria DNA Heteroplasmy SNPs Compared to Blood Open Access

Cristina Kenney; Marilyn Chwa; Shari Atilano

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 416. doi:

Pathognomonic clinical features of non-typical cone dystrophy with hearing impairment caused by loss-of-function variants in CEP250 Open Access

Suzanne E. de Bruijn; Lonneke Haer-Wigman; Martha J.H. Tjon-Fo-Sang; Hannie Kremer; Frans P Cremers; Susanne Roosing; L. Ingeborgh van den Born

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 418. doi:

Digenic triallelic inheritance in cone photoreceptor cyclic nucleotide gated channel associated retinopathies Open Access

Susanne Kohl; Markus Burkard; Timm Kraetzig; Naoyuki Tanimoto; Britta Baumann; Martin Biel; Robert Lukowski; Mathias W Seeliger; Stylianos Michalakis; Bernd Wissinger; Peter Ruth

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 419. doi:

Identification of splicing defects due to deep-intronic or non-canonical splice site variants in ABCA4 Open Access

Zeinab Fadaie; Mubeen Khan; Frans P Cremers; Susanne Roosing

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 420. doi:

A whole exome sequencing-based panel assay with boosted clinical content generates a high diagnostic yield in patients with inherited eye diseases Open Access

Kati Kämpjärvi; Kirsty Wells; Miika Mehine; Johanna Känsäkoski; Laura Sarantaus; Hanna Västinsalo; Jennifer Schleit; Inka Saarinen; Mikko Muona; Samuel Myllykangas; Tero-Pekka Alastalo; Juha Koskenvuo; Jussi Paananen; Sari Tuupanen

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 421. doi:

NMNAT1 is the most frequently mutated gene in Leber congenital amaurosis in South Korea Open Access

Dongheon Surl; Junwon Lee; Suk Ho Byeon; Christopher Seungkyu Lee; Jinu Han

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 422. doi:

The identification of a RNA splice variant in TULP1 in two siblings with early-onset photoreceptor dystrophy Open Access

Susanne Roosing; Sanne K Verbakel; Zeinab Fadaie; Jeroen Klevering; Maria M. van Genderen; Ilse Feenstra; Frans P Cremers; Carel C B Hoyng

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 423. doi:

Modelling Sorsby’s Fundus Dystrophy using patient-derived iPSC-RPE Open Access

Jennifer Dewing; David R. G. Christensen; Heidi Hongisto; Jennifer Scott; Ben Jenkins; Angela Jane Cree; Heli Skottman; J. Arjuna Ratnayaka; Andrew Lotery

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 424. doi:

High myopia and strabismus induced by a deep intronic mutation in COL2A1 Open Access

Shirel Weiss; Naama Orenstein; Alon Zahavi; Nitza Goldenberg-Cohen

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 425. doi:

A frequent variant in the Japanese population determines quasi-Mendelian inheritance of rare retinal ciliopathy Open Access

Carlo Rivolta

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 426. doi:

microRNAs expression profiling in retinal and choroidal tissues in an oxygen-induced retinopathy (OIR) model Open Access

michel desjarlais; Jose Carlos Rivera; isabelle lahaie; Sylvain Chemtob

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 427. doi:

Cyclooxygenase-1 (COX-1) modulates neuroinflammation in the rd10 mouse model of retinitis pigmentosa Open Access

Bin Lin; Wei Yang; Meng Cheng; Rong Li

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 430. doi:

Mitochondria Defects Constitute an Early Step in Retinal Degeneration Open Access

Ke Jiang; Anupam Mondal; Yogita Adlakha; Matthew Brooks; Linn Gieser; Jessica Gumerson; Kim Jung-Woong; Raul Covian Garcia; Anand Swaroop

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 431. doi:

Minocycline suppresses microglial Ccr2 expression in inherited retinal degeneration Open Access

Ryo Terauchi; Tsutomu Sakai; Tadashi Nakano; Hideo Kohno

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 432. doi:

Fundus autofluorescence abnormalities and microglia/macrophage activation in the Rpgr-deficient mouse. Open Access

Federica Staurenghi; Cristina Martinez-Fernandez dela Camara; Alun R Barnard; Robert E MacLaren

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 433. doi:

Characterization of adRP-associated rhodopsin missense mutations in transgenic Xenopus laevis rod photoreceptors Open Access

Aaron Daniel Loewen; Beatrice M Tam; Colette N Chiu; Orson L Moritz

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 434. doi:

Myo/Nog cells increase in areas of stress in a mouse model of retinitis pigmentosa Open Access

Samantha Murad; Mary Woodruff; Rushil Brahmbhatt; Paul Lecker; Alexa Noel McGrath; Serena Young; Grzegorz Gorski; Mindy George-Weinstein; Arturo Bravo-Nuevo

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 435. doi:

Effects of Ca²⁺-channel blockers on photoreceptor Ca²⁺-levels and activity of calpains Open Access

Soumyaparna Das; Michael Power; Luke Rogerson; Thomas Euler; Francois Paquet-Durand

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 436. doi:

Characterization of photoreceptors, RPE, and Müller glia conditional knockouts of AdipoR1 Open Access

Marie-Audrey Ines Kautzmann; Khanh Do; William C Gordon; Nicolas G Bazan

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 437. doi:

Loss of the Peripherin-2/rds (P/rds) C-terminal Domain Causes Progressive Retinal Degeneration in a New Mouse Model of Human Retinal Disease. Open Access

Breyanna Lynn Cavanaugh; Michelle Lynn Milstein; Adam C Seidel; Mario Hanna; Sharon X Tan; Andrew F X Goldberg

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 438. doi:

Modelling cone-rod dystrophy in genetically-modified African clawed frog (Xenopus laevis) Open Access

Brittany Jane Carr; Paloma Stanar; Beatrice M Tam; Orson L Moritz

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 440. doi:

Development of knock in (KI) mouse models of rhodopsin retinitis pigmentosa Open Access

Kelly Ziaka; Kwan-Leong Hau; Dimitra Athanasiou; Rosellina Guarascio; Mònica Aguilà; James Bellingham; Smriti A. Agrawal; Yumei Li; Rui Chen; Michael E Cheetham

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 441. doi:

Transplanted photoreceptors exchange proteins to host photoreceptors via neurites Open Access

Arturo Ortin-Martinez; En Leh Samuel Tsai; Lacrimioara Comanita; Nicole Yan; Nobuhiko Tachibana; Akshay Gurdita; Zhongda Chris Liu; Philip Nickerson; Suying Lu; Rod Bremner; Valerie Wallace

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 442. doi:

Analysis of arrestin knockout in a T4K rhodopsin model of retinitis pigmentosa in X. laevis Open Access

Beatrice M Tam; Orson L Moritz

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 443. doi:

The phagocytic function of Müller glia in a mouse model of retinitis pigmentosa Open Access

Sanae Sakami; Yoshikazu Imanishi; Krzysztof Palczewski

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 444. doi:

Novel model for blindness generated using inducible genome editing in zebrafish Open Access

Michael D Varnum; Lin Fang; Peter Meighan; Owen Canterbury; Tshering Sherpa

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 445. doi:

Development of a Pde6b Gene Knockout Rat Model for Studies of Degenerative Retinal Diseases Open Access

Joonhyung Yeo; Bok Kyoung Jung; Young Hoon Sung; In-Jeoung Baek; Joo Yong Lee

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 447. doi:

Steroids and photoreceptor survival in two models of retinal degeneration Open Access

Melisa Daniela Marquioni Ramella; Pablo Tate; Mariela Marazita; Angela M Suburo

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 448. doi:

REEP6 regulates expression of phototransduction proteins and modulates metabolism in rod photoreceptors Open Access

Tongdan Zou; Houbin Zhang

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 449. doi:

Lack of overt pathology in a K42E knock-in mouse model of retinitis pigmentosa (RP59) Open Access

Steven J Fliesler; Pravallika Kotla; Sriganesh Ramachandra Rao; Steven J. Pittler

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 450. doi:

Screening tools in zebrafish for modifiers of inherited rod degeneration Open Access

James M Fadool

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 451. doi:

Stanniocalcin-1 enhances ellipsoid zone intensity and cone function in the P23H rhodopsin transgenic pig Open Access

Wankun Xie; Min Zhao; Shu-Huai Tsai; Maxwell Su; Travis W Hein; Lih Kuo; Robert H Rosa

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 452. doi:

Early Treatment with Mycophenolate Reduces Microglial Migration in rd10 mice Open Access

Paul Yang; Hope Titus; Kyle Weller; Robert Duvoisin; Richard Weleber; Catherine W Morgans; Mark E Pennesi

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 453. doi:

Conditional ablation of NMNAT1 in the murine retina leads to rapid and severe retinal degeneration likely associated with distinct changes in the retinal metabolome Open Access

David Sokolov; Emily Sechrest; Joseph Murphy; Yekai Wang; Jianhai Du; Saravanan Kolandaivelu

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 454. doi:

CRISPR/Cas9 mutagenesis of the mtnr1a melatonin receptor gene causes rod photoreceptor dystrophy in premetamorphic Xenopus tropicalis Open Access

Allan F Wiechmann; Teryn Martin; Marko E Horb; David M Sherry

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 455. doi:

Photoreceptor damage caused by human mutant T8993G ATP6 in a transgenic mouse model of Leigh syndrome and NARP Open Access

Huijun Yuan; John Guy

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 456. doi:

Pathophysiology of voltage-gated potassium channels in a mouse model of cone-rod dystrophy Open Access

Xiaotian Jiang; David M Hunt; Livia S Carvalho

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 457. doi:

New large animal model for RDH5-associated retinopathies Open Access

Simon M Petersen-Jones; Laurence Occelli; Paige Winkler; Andrea Minella; Kelian Sun; Leslie Lyons; Anahita Daruwalla; Philip Kiser; Krzysztof Palczewski

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 458. doi:

Conditional Deletion of Lamb2Produces A Novel Progressive Retinal Degeneration Open Access

William J Brunken; Galina Bachay; Yumiko Umino; Eduardo C Solessio; Xiguang Yang; Dale D. Hunter

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 459. doi:

Novel Zebrafish Autosomal Recessive Retinitis Pigmentosa Disease Models Created by CRISPR/Cas9 Gene Editing Open Access

Liyun Zhang; Arife Unal Eroglu; Timothy Mulligan; Jie Dong; Emilie Cheng; Naveena Murugan; Wuhong Pei; Lisha Xu; Shawn Burgess; Meera Saxena; Jeff S Mumm

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 460. doi:

Monocyte-derived macrophages exacerbate cone degeneration in a mouse model of retinitis pigmentosa Open Access

Jun Funatsu; Yusuke Murakami; Shotaro Shimokawa; Shunji Nakatake; Kohta Fujiwara; Toshio Hisatomi; Kensuke Shibata; Yasuhiro Ikeda; Koh-hei Sonoda

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 461. doi:

Isoform-specific Rpgrmutant mice depict distinct roles of the RPGR isoforms in photoreceptors Open Access

Wei Zhang; Lijing li; Ramesh Periasamy; Laura Moreno Leon; Manisha Anand; Michael Brodsky; Hemant Khanna

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 462. doi:

In depth characterization of a pig model of photoreceptor degeneration Open Access

Francesca BARONE; Luisa Vera Muscatello; Domenico Ventrella; Alberto Elmi; Luca Laghi; Fabio Benfenati; Grazia Pertile; Maria Laura Bacci

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 463. doi:

Early-onset inner retina degeneration in a mouse model of retinitis pigmentosa Open Access

Arpad Palfi; Adlet Yesmambetov; Gwyneth Jane Farrar

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 464. doi:

Autosomal recessive night blindness with progressive photoreceptor degeneration in a dog model Open Access

Luis Lima Pompeo Marinho; Laurence Mireille Occelli; Nate Pasmanter; Andre Tavares Somma; Fabiano Montiani-Ferreira; Simon M Petersen-Jones

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 465. doi:

STAT3 is a potential genetic modifier of photoreceptor gene expression during stress Open Access

Casey Keuthan; Clayton Santiago; John D Ash

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 466. doi:

Mouse proteomic analysis demonstrates a critical role for phototransduction in an RS1^-/y mouse model Open Access

Lucia Ambrosio; James D Akula; Shira Rockowitz; Ronald M Hansen; Anne B Fulton

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 467. doi:

Lower Capsular Complication Rates in Pop and Prechop than Divide and Conquer and Pop and Chop in Novice Resident Cataract Surgeons Open Access

Lawrence Dean Flanders; Fredric Jay Gross; Kanika Agarwal; Joy Strawn; Apoorv Chebolu

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 469. doi:

The effects of fine motor hobbies on cataract surgical simulator performance. Open Access

Laura Palazzolo; Anna Kozlova; Allison E Rizzuti

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 470. doi:

Comparison of Delivery Forces and Wound Dimensions of New Smaller Incision Injector for Plate-Haptic Intraocular Lens Open Access

George Lau; Sushant Muchhala; Andrew Pilon; Valeri Kolesnitchenko; Ehsan Sadri

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 471. doi:

Australian Experience with Intraocular Lens Product Flaws Open Access

Zixin Hong; Elaine Chong; Alexander Ioannidis; Mark Daniell; Robert Charles Andrew Symons

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 472. doi:

Comparison of Ocular Biometry and Refractive Outcomes Using 3 Different Devices: IOL Master 500, IOL Master 700 and Lenstar LS900 Open Access

JAE SHIN SONG; Do Yeh Yoon; Joon-Young Hyon; Hyun Sun Jeon

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 474. doi:

Crowdsourcing to assess resident surgical skill proficiency in cataract surgery Open Access

Grace L Paley; Jenny Chen; Bradley Wilson; Mae O Gordon; Susan M Culican

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 475. doi:

Sutureless Intrascleral Fixation of Intraocular Lenses: Three-Year Clinical Outcome Review Open Access

Nathan Farley; Elizabeth Marlow; Mavis Gappy; Hamzeh Omar; Jeremy Wolfe

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 476. doi:

Reliability and reproducibility of a new semi automated evaluation method for intraocular lens rotation – Rotix Open Access

Daniel Schartmüller; Sabine Schriefl; Luca Schwarzenbacher; Christina Leydolt; Rupert Menapace

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 477. doi:

Expression profile of inflammatory cytokines in congenital cataract after Lensectomy and Anterior Vitrectomy Open Access

Yinying Zhao; Yune zhao; Zhangliang Li; pingjun chang

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 478. doi:

Optimizing prediction of refractive outcomes after cataract surgery using a biometry-based scoring rubric Open Access

Diane Haeji Jang; Andrew Luo; Jack Quillen; Tara O'Rourke; Ingrid U Scott; Seth Pantanelli

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 479. doi:

Preoperative topical prostaglandin use and the incidence of postoperative cystoid macular edema and persistent inflammation after cataract surgery Open Access

Alina Lou; David Vollman; Mary K Daly; Qingxia Chen; Amy Chomsky

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 480. doi:

Intraocular Lens Power Prediction for Cataract Surgery in Eyes with Corneal Ectasia Open Access

Kendrick Wang; Divya Srikumaran; Albert S Jun

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 482. doi:

Outcomes of resident performed cataract surgery with toric intraocular lens implantation Open Access

Kari Fossum; Nina Farivari; Eric N Brown; Jennifer Lindsey

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 483. doi:

Axial Length Measurement by Immersion B-Scan Open Access

Suzanne Daly; D Jackson Coleman; Danielle Trief; Ronald H Silverman

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 484. doi:

Three Cases of Scleral Sutured EnVista Intraocular Lens Dislocation and Determination of the EnVista Eyelet Tensile Strength Under Two Different Suturing Methods Open Access

John Lippincott; Brian Tieu

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 485. doi:

Intraoperative optical coherence tomography during cataract surgery in the DISCOVER study Open Access

Rachel C Chen; Michael E. Millstein; Sunil K Srivastava; Jamie L. Reese; Justis P Ehlers

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 486. doi:

Visual acuity from time of cataract surgery to Nd: YAG laser capsulotomy Open Access

Carson Petrash; Jennifer Patnaik; J. Mark Petrash; Anne Lynch; Michael Taravella; Richard Davidson; Karen Christopher

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 487. doi:

Is preoperative tropicamide required when using Mydrane? Open Access

Ivan Sychev; Matthew Fenech; Raly Job Vellaniparambil; Dan Nguyen; Pedro Muel-Gonzalez

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 488. doi:

Impact of Video Coaching on Ophthalmology Resident Capsulorhexis Performance in Cataract Surgery Open Access

Danielle Lo; Michael Main; Priya Patel; Habeeb Ahmad

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 489. doi:

Intraocular Lens Implantation Performed First to Protect The Posterior Capsule in Morgagnian Cataracts during Phacoemulsification Open Access

Dong YongXiao; Xia Hua; Jianying Du; Xiaoyong Yuan

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 490. doi:

Complications in resident-performed phacoemulsification cataract surgery at an ophthalmology center in Mexico City: Results of 7 years. Open Access

Ruben Espino Icazbalceta; DANIELA PULIDO LONDON; Daniela Alanis Cabrera; FERNANDO SOLORIO; EDUARDO CHAVEZ MONDRAGON

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 491. doi:

Preoperative factors causing refractive errors after cataract surgery Open Access

Kwang hyun Kim

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 492. doi:

Retinal detachment in high myopia after cataract surgery : retrospective study about 365 cas. Open Access

Zerin HEKALO; Zaidi Mohamed; Louis Lhuillier; alexandre schaut; George Hayek; Sarah Stoebener; Clément Gisquet; christophe goetz; Jean-Marc Perone

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 493. doi:

Investigation of postoperative refractive error of intraocular lens suturing and intrascreral fixation Open Access

Masashi Kakinoki; Osamu Sawada; Yoshitsugu Saishin; Yusuke Ichiyama; Shumpei Obata; Masahito Ohji

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 494. doi:

Using topographical axis as an indicator for sub-clinical dry eye in patients undergoing cataract surgery Open Access

Pathmanathan Pathmaraj

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 495. doi:

Predictors of Non-adherence to Follow-up after Cataract Surgery: Results from the PCIOL Study Open Access

Giannis A. Moustafa; Durga S Borkar; Emily A. Eton; Nicole Koulisis; Carolyn E. Kloek

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 496. doi:

A novel device for secondary intraocular lens placement: Design and Ex Vivo Evaluation Open Access

David Buickians; David Myung; Mark S Blumenkranz; Frank Brodie

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 497. doi:

Comparison of predicted refractive outcomes between different methods of toric IOL calculating methods Open Access

Shinichiro Nakano; Takahiro Hiraoka; Tetsuro Oshika

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 498. doi:

Glaucoma as a risk factor for early pseudophakic macular edema – an analysis of 1000 cataract surgeries Open Access

Robert Hoerster; Carl von Netzer; Leonie Schulze; Jonas Obstmayer; Erdal Tahmaz; Ludwig M Heindl

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 499. doi:

VISUAL FUNCTION AND QUALITY OF LIFE IN PATIENTS SUBMITTED TO CATARACT SURGERY WITH BILATERAL IMPLANT OF EXTENDED RANGE OF VISION INTRAOCULAR LENS. Open Access

Erick Rebolledo Enríquez; Amanda Cáceres Marín; Eduardo Chavez Mondragón; DANIELA PULIDO LONDON; Diego Zamora de la Cruz; Marisol Garzón

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 500. doi:

A web-based evaluation tool to assess surgical skill proficiency during ophthalmology residency – a multicenter longitudinal study Open Access

Hui Zhao; Grace L Paley; Susan M Culican

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 501. doi:

Incidence of postoperative complications after cataract surgery with intraoperative floppy iris syndrome Open Access

Frini Makadia; Mary K Daly; David Vollman; Qingxia Chen; Amy Chomsky

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 502. doi:

Impact of Pre-operative Spectacle Prescription on Accuracy of Holladay2 IOL Power Predictions Open Access

Rishi Singhal; Ellen Schlosser; Andrew Luo; Diane Jang; Jack Quillen; Tara O'Rourke; Ingrid U Scott; Seth Pantanelli

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 503. doi:

Comparison of 4 intraocular lens power calculations for Japanese eyes with short and long axial length Open Access

Yosai Mori; Tadatoshi Tokunaga; Katsuhito Kinoshita; Keiichiro Minami; Kazunori Miyata

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 504. doi:

Influence of the posterior corneal surface in the residual astigmatism in patients undergoing phacoemulsification and implant of toric intraocular lens. Open Access

Jacobo Jacobo Resendiz; Cynthia Solís Hernández; Claudia Palacio Pastrana

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 505. doi:

Impact of tear osmolarity in the biometric pre-assessment for phacoemulsification surgery Open Access

LAURA ALEJANDRA GONZALEZ DIBILDOX; Guadalupe Cervantes Coste; MARA CANTU TREVIÑO; ARGELIA AVENDAÑO DOMINGUEZ; CLAUDIA CORREDOR ORTEGA; CECILIO VELASCO BARONA; JAIME VILLASEÑOR DIEZ; Roberto Gonzalez-Salinas

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 506. doi:

Incidence and Associated Risk Factors of Suspected Glaucoma and Glaucoma after Congenital Cataract Surgery: A Longitudinal Follow-up Study in China Open Access

Jinghui Wang; Weirong Chen; Yizhi Liu; Haotian Lin

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 507. doi:

A Cost Analysis of an Expedited Pre-operative Anesthesia Pathway for Cataract Surgery Open Access

Cory Hoeferlin; Justin Park; Lauren Daskivich; Pradeep Prasad

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 508. doi:

Cyclorotation and docking induced rotation of the eye with Femto-second cataract laser Open Access

David Dewey; Tianheng Wang; Neil Friedman; Javier Gonzalez; Kavita Dhamdhere; Sanjeev Kasthurirangan; Janice Tarrant; Audrey Jonas

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 509. doi:

The financial burden of activity restrictions following cataract surgery Open Access

Darren C Hill; John Conklin; Eric Higgins

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 511. doi:

Visual Outcomes of Patients with Posterior Capsule Complications In Early Resident Cataract Surgery Open Access

Kanika Agarwal; Lawrence Dean Flanders; Joy Strawn; Samuel Tyson; Fredric Jay Gross

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 512. doi:

Comparison of Different Methods for Photopic and Scotopic Pupil Diameter Measurement and Clinical Analysis on the Pupil diameter changes of cataract patients Open Access

Yong Wang

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 513. doi:

Predicitive Factors of Cystoid Macular Edema After Sutured Lens Implants Open Access

Mark Barakat

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 514. doi:

The Cataract Quality Outcome Initiative: assessing visual acuity and vision function before and after cataract surgery in Ontario, Canada Open Access

Wendy Hatch; Victoria Leung; Negar Omali; Kylen McReelis; Karen Pope; Ike Ahmed; Matthew Schlenker; Sherif El Defrawy

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 515. doi:

ANGLE KAPPA IN MYOPES AND HYPEROPES AND ITS ROLE IN MULTIFOCAL LENS IMPLANTATIONS Open Access

saraswati sivakumar; Rayirth sivakumar

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 516. doi:

Pilot study of aspheric, hydrophobic, acrylic intraocular lens (IOL) design with uniques optic holes. Open Access

Shruti Mahajan; Rohit Om Parkash; tushya om parkash

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 517. doi:

To look or not to look: study of reflexive eye movements Open Access

PremNandhini Satgunam; Eswar Kurni

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 518. doi:

Characteristics of saccades when testing the near point of convergence Open Access

Clara Mestre; Josselin Gautier; Harold E Bedell; Fernando Diaz Douton; Jaume Pujol

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 519. doi:

Microvergence fixational eye movements Open Access

Daria Ivanchenko; Frank Schaeffel; Ziad Hafed

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 520. doi:

Reliability of oculomotor kinematics, visual attention, and vehicle operation in driving simulation Open Access

Hayden M Green; Victor M Borges; Charlotte W J Connell; David Newcombe; Ben Thompson; Nicholas Gant

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 521. doi:

Validation of a novel gaze-contingent perimeter with high-speed eye tracking Open Access

Nikita Thomas; Jennifer H. Acton; Jonathan T. Erichsen; Matt J. Dunn

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 522. doi:

Saccades in Parkinson’s disease: hypometric, slow, or maladaptive? Open Access

Aasef Shaikh; Fatema Firoz Ghasia

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 523. doi:

Fixation Stability Before and After Amblyopia Therapy. Open Access

William H Ridder; Reena A Patel; Apoorva Karsolia; Deborah Duan; Lani May Centeno

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 524. doi:

Age-related inhibitory deficits in cognitive control of eye movements Open Access

Rui Jin; Larry A Abel

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 525. doi:

Student eye movements to optic nerves Open Access

Amanda Douglass; Larry A Abel; James Armitage

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 526. doi:

Decrease in task performance associated with changes in fixations in optically misaligned binocular night vision systems Open Access

Larry A Abel; Amanda Douglass; Renee Karas; Maria Gavrilescu; Peter Gibbs

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 527. doi:

The Effect of Modified Anderson Procedure for Abnormal Head Position in Infantile Nystagmus Open Access

SangCheol Yang; HYESHIN JEON; Hee-Young Choi

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 528. doi:

Characterization of the retinal phenotype of the C57BL/6-c2J mouse model of human oculocutaneous albinism: implications for treatment development Open Access

Jennifer Ann Scott; Aida Sanchez-Bretano; Helen Griffiths; Jon Ward; Chiamaka Dibigbou; Flavie Soubigou; James Edward Self; Andrew Lotery; J. Arjuna Ratnayaka; Helena Lee

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 529. doi:

Proof of concept for oral Levodopa treatment in rescuing retinal morphology and visual function in a murine model of human albinism Open Access

Helena Lee; Jennifer Scott; Helen Griffiths; James Edward Self; Andrew Lotery

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 530. doi:

Intelligentized functional electrical stimulation can treat congenital nystagmus Open Access

Lejin Wang; Zequn Miao

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 531. doi:

Repeatability of Contrast Sensitivity in Patients with Infantile Nystagmus Syndrome Using the CSV-1000^R Open Access

ABIGAIL R. KRAFT; Alyssa M Gehring; Richard W Hertle; Tawna L Roberts

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 532. doi:

Two surgical techniques for correction of vertical abnormal head position in infantile nystagmus syndrome – clinical characteristics and outcomes Open Access

James Jian-Yin Law; Derick Holt; Yuxi Zheng; David Morrison; Sean Donahue

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 533. doi:

Feasibility of a home-based visual training app for youth with infantile nystagmus Open Access

Steven Ligthert; Jeroen Goossens; Bianca Huurneman

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 534. doi:

Torsional nystagmus in pediatric patients with cerebellar hypoplasia. Open Access

James Phillips; Avery H Weiss; Michael Brodsky; John P Kelly

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 535. doi:

In search of an objective measure of visual vertigo - eye movement responses to balance provoking stimulation Open Access

Tobias Wibble; Tony Pansell

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 536. doi:

The sensory specific effects of prescription-free motion sickness medication - eye movement responses to balance provoking stimulation Open Access

Tony Pansell; Johanna Engström; Tobias Wibble

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 537. doi:

The distribution of nNOS amacrine cells in the guinea pig retina Open Access

Sally A McFadden; Jose M Romero Hombrebueno; Guang Zeng; Dominique (Lena) Fuchs; Eun-Jin Lee

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 539. doi:

Anatomical and molecular characterization of CRH (corticotropin-releasing hormone) receptor 1-expressing cell populations in the mouse retina Open Access

Hannah Walsh; Pouyan Rahmani; Kathy Zhang; In-Jung Kim; Nicholas J. Justice; Jonathan B Demb; Joseph Pottackal

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 540. doi:

Gbx2 identifies and regulates the development of an atypical amacrine cell in the mouse retina. Open Access

Patrick C Kerstein; Joseph Leffler; Ben Sivyer; William Rowland Taylor; Kevin M Wright

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 541. doi:

Axon-bearing amacrine cells labelled in transgenic GlyT2 mice. Open Access

Ben Sivyer; Marc Andrew Meadows; Patrick C Kerstein; Kevin M Wright; Henrique Von Gersdorff

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 542. doi:

MODULATION OF VIP-1 AMACRINE CELL COUPLING BY DOPAMINE IN THE MOUSE RETINA Open Access

Luis Perez de Sevilla Muller; Janira de los Santos; Nicholas Brecha

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 543. doi:

The presence of recombinase activity in just one type of wide-field ON-OFF amacrine cells in a DAT-Cre mouse line Open Access

Yu-Jiun Chen; Hung-Ya Tu; Yen-Lin Chen; Allison Shay; Annie Zhang; Ching-Kang Jason Chen

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 544. doi:

Glycinergic inhibition tunes direction selectivity in the mammalian retina Open Access

Varsha Jain; Laura Hanson; Gautam B Awatramani

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 545. doi:

Synaptic mechanisms underlying direction selectivity in starburst amacrine cell dendrites Open Access

Laura Hanson; Gautam B Awatramani

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 546. doi:

Regulation of neurotransmitter release during crossover inhibition Open Access

Marc Andrew Meadows; Veeramuthu Balakrishnan; Xiaohan Wang; Henrique Von Gersdorff

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 547. doi:

Comparative anatomy and connectivity of the Aii amacrine cell in mouse and rabbit retina Open Access

Selena Wirthlin; Crystal Sigulinsky; James Anderson; Daniel Emrich; Christopher Rapp; Jeebika Dahal; Rebecca L Pfeiffer; Kevin Rapp; Jia-Hui Yang; Carl Watt; Robert Marc; Bryan W Jones

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 548. doi:

Proton-mediated inhibition of L-type Ca²⁺ currents in AII amacrine cells Open Access

Katherine Thanyamongkhonsawat; Marc Andrew Meadows; Henrique Von Gersdorff

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 549. doi:

CaBP5 and Munc13-2 regulate rod bipolar cell to AII amacrine cell synaptic transmission Open Access

Maxim Kozhemyakin; Ruth Heidelberger

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 550. doi:

Aii Amacrine Cell Connectivity in Degenerating Retina Open Access

Jeebika Dahal; Rebecca L Pfeiffer; Crystal Sigulinsky; James Anderson; Daniel Emrich; Hope Morrison; Jessica Garcia; Kevin Rapp; Jia-Hui Yang; Carl Watt; Mineo Kondo; Hiroko Terasaki; Robert Marc; Bryan W Jones

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 551. doi:

Functional divergence at the mouse type 6 bipolar cell terminal Open Access

David I Swygart; Greg Schwartz; Rachel O Wong; Wan-Qing Yu

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 552. doi:

AMPA receptor plasticity of On α RGCs revealed by optogenetic stimulation of inputs Open Access

Scott A Nawy; Asia L. Cahill

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 553. doi:

Changes in Inhibitory Retinal Circuits Following Partial Cone Loss Open Access

Joo Yeun Lee; Rachel Care; Felice Dunn

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 554. doi:

OFF-layer Branches of ON Cone Bipolar Cells in Early Retinal Degeneration Open Access

Jessica Garcia; Rebecca L Pfeiffer; Crystal Sigulinsky; James Anderson; Daniel Emrich; Jeebika Dahal; Hope Morrison; Kevin Rapp; Jia-Hui Yang; Carl Watt; Mineo Kondo; Hiroko Terasaki; Robert Marc; Bryan W Jones

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 555. doi:

Contacts between axon terminals of rod bipolar cells and somas of ganglion cells in the mouse retina Open Access

Ji-Jie Pang; Samuel M Wu

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 556. doi:

Dopamine decreases excitatory inputs to ON sustained ganglion cells via both D1 and D4 receptor-dependent pathways Open Access

Michael Flood; Erika D Eggers

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 557. doi:

The effect of arrestin-1 self-association on its distribution in rods Open Access

Vsevolod V Gurevich; Srimal Aminda Samaranayake; Sergey A Vishnivetskiy

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 558. doi:

Divergent conformations of the arrestin-rhodopsin complex in solution Open Access

Sergey A Vishnivetskiy; Matthias Elgeti; Ned Van Eps; Nicole A Perry; Wayne Hubbell; Vsevolod V Gurevich

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 559. doi:

Arrestin-1 in rod synaptic terminals Open Access

Eugenia V Gurevich; Srimal Aminda Samaranayake; Sergey A Vishnivetskiy; Vsevolod V Gurevich

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 560. doi:

Thyroid hormone receptor beta mutations alter or eliminate the signals of long-wavelength cones in zebrafish retina Open Access

Ciana Deveau; Asha Krishnakumar; xiaodong jiao; Sachihiro Suzuki; Takeshi Yoshimatsu; J Fielding Hejtmancik; Rachel O Wong; Ralph F Nelson

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 561. doi:

Cone sensitivity is diminished, but not absent, in Cpfl3 mice Open Access

Natalie Seulki Chen; Norianne T Ingram; Gordon L Fain; Jeannie Chen

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 562. doi:

LIGHT-DEPENDENT RECOVERY OF SENSITIVITY AFTER BLEACHING BY PHOTOISOMERIZATION OF RGR IN MOUSE CONES Open Access

Ala Morshedian; Rikard Frederiksen; Alapakkam P Sampath; Joanna J. Kaylor; Gabriel H Travis; Gordon L Fain

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 563. doi:

Ablation of cAMP-dependent GRK1 phosphorylation suppresses dark adaption of rod photoreceptors Open Access

Alexander V Kolesnikov; Jared Chrispell; Vladimir Kefalov; Ellen R Weiss

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 564. doi:

Cone mitochondria shape cytosolic Ca²⁺ transients and recovery of the photoresponse Open Access

Rachel Hutto; Fatima Abbas; Celia Bisbach; James Hurley; Frans Vinberg; Susan Brockerhoff

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 565. doi:

Mitochondrial Biogenesis in Zebrafish Cone Photoreceptors Open Access

Daniel Christopher Brock; Michelle Giarmarco; Whitney Cleghorn; Kristine Tsantilas; William Ge; Susan Brockerhoff

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 566. doi:

Modeling Cone Aerobic Glycolysis Open Access

Erika Tatiana Camacho; Danielle Brager; Ghizlane Elachouri; Tatyana Korneyeva; Geraldine Millet-Puel; Jose Alain Sahel; Thierry D Leveillard

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 567. doi:

Modulation of mouse rod signaling by llama-derived transducin nanobody Open Access

Guhan Iyer; Sahil Gulati; Krzysztof Palczewski; Vladimir Kefalov

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 568. doi:

Mathematically Assessing the Contributions of Key Processes in Cone Aerobic Glycolysis Open Access

Danielle Brager; Erika Tatiana Camacho; Ghizlane Elachouri; Tatyana Korneyeva; Geraldine Millet-Puel; Jose Alain Sahel; Thierry D Leveillard

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 569. doi:

The role of constitutively active RAC1 in rod out segment formation in mouse rhodopsin-null rods Open Access

Hongman Song; Yong Zeng; Ronald A Bush; Ronald S Petralia; Ya Xian Wang; Robert N Fariss; Camasamudram Vijaysarathy; Paul A Sieving

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 570. doi:

Multiquantal release from rod ribbons is facilitated by syntaxin3B. Open Access

Cassandra Hays; Justin J Grassmeyer; Roger Janz; Ruth Heidelberger; Wallace B Thoreson

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 571. doi:

EML1 modulates phototransduction in mouse rod photoreceptors Open Access

Deepak Poria; Oleg G Kisselev; Vladimir Kefalov

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 572. doi:

Peripherin-2/rds functions for photoreceptor disk morphology by bending membranes Open Access

Andrew F X Goldberg; Michelle Lynn Milstein; Breyanna Lynn Cavanaugh; Stefanie Volland; David S Williams

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 573. doi:

Dendritic voltage-gated K⁺ currents stabilize response amplitude and speed on a computational model of the rod-driven ON bipolar cell Open Access

Kae Leopoldo; Maarten Kamermans; Christina Joselevitch

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 574. doi:

Vesicular Ca²⁺ sensor Synaptotagmin-1 mediates neurotransmission from mammalian rods and cones Open Access

Wallace B Thoreson; Justin J Grassmeyer; Cassandra L. Hays; Asia L. Cahill; Norbert Babai

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 575. doi:

AMPA-DART silencing of horizontal cells in mouse retinal slices Open Access

Nicholas Brecha; Shashvat Purohit; James CR Grove; Janira de los Santos; Arlene A Hirano; Michael R Tadross; Steven A Barnes

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 576. doi:

AAV2/6 transduce to cone photoreceptors Open Access

Tesshu Hori; Masashi Fukutome; Chiseto Maejima; Satoru Moritoh; Kenta Kobayashi; Chieko Koike

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 577. doi:

Identification of PKCα-dependent phosphoproteins in mouse retina Open Access

Catherine W Morgans; Colin M Wakeham; Philip A Wilmarth; Gaoying Ren; john E Klimek; Jennifer M Cunliffe; Larry L David

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 578. doi:

TPBG: A PKCα-dependent phosphoprotein in rod bipolar cells plays a role in the light response Open Access

Colin M Wakeham; Tammie L Haley; Gaoying Ren; Catherine W Morgans

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 579. doi:

Contributions of cones to retinal adaptation to naturalistic visual inputs Open Access

Fred Rieke; Julian Freedland; Philip Mardoum

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 580. doi:

A dark decrement for enhancement of incremental sensitivity in vertebrate photoreceptors Open Access

Richard L Chappell; Shen Hu; Malcolm Slaughter

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 581. doi:

Structural and Functional Alterations in Tuberous Sclerosis Complex 1 (Tsc1)-Deficient Mouse Retina Open Access

SHARON JIYOON JUNG; Ji-Heon Choi; Seung Hee Lee; Sun Sook Paik; Hong Lim Kim; Jin Woo Kim; IN-BEOM KIM

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 582. doi:

Isolation of pure S-cone responses in the ultraviolet-elicited photopic electroretinograms under a bright middle-wave background Open Access

Rumi Kawashima; Kenji Matsushita; Kazuki Kuniyoshi; Kohji Nishida

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 584. doi:

S-cone function in Blue Cone Monochromacy Open Access

Jennifer R Chao; Xiaoyun Jiang; James A Kuchenbecker; Anna-Lisa Doebley; Maureen Neitz; Jay Neitz; Ramkumar Sabesan

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 585. doi:

UV-cones differentially encode contrast in vivo to support distinct visual functions across visual space Open Access

Takeshi Yoshimatsu; Cornelius Schröder; Philipp Berens; Tom Baden

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 586. doi:

Rod and cone photoresponsivity in the developing mouse retina Open Access

Paul Bonezzi; Matthew Tarchick; Maureen Stabio; Jordan M Renna

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 587. doi:

Light induced changes of the outer temporal retina observed with optical coherence tomography Open Access

Alina Messner; Rene Marcel Werkmeister; Gerald Seidel; Hannes Stegmann; Leopold Schmetterer; Valentin Aranha dos Santos

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 588. doi:

Computational model of sclerotic scatter Open Access

Fiona Johnston; Arthur Ho; Minas T Coroneo

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 589. doi:

A Novel 3D-Printed Eye Model for Practicing Indirect Ophthalmoscopy and Retinal Laser Photocoagulation Open Access

Danny Diaz; Mohammad Dahrouj; Tedi Begaj; Jan A. Kylstra

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 590. doi:

Automated Eye Model for Refraction and Vision Open Access

Noam Sapiens; Paul TanPiengco; John Serri

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 591. doi:

Optical performance of phase-step contact lenses in the Arizona model eye Open Access

Karen Lahav-Yacouel; Arthur Ho; Ravi Chandra Bakaraju

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 592. doi:

Clinical Measurement of Posterior Corneal Astigmatism in Normal Corneas Open Access

George Asimellis

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 593. doi:

Simulated optical and visual impact of wavefront-guided scleral lens misalignment Open Access

Sujata Rijal; Gareth D Hastings; Lan Chi Nguyen; Matthew J. Kauffman; Raymond A Applegate; Jason D Marsack

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 594. doi:

WITHDRAWN_A comparison of refraction data from Hartmann-Shack wavefront and adaptive optics visual simulator to other established methods of refraction Open Access

Carles Otero; Juan Tabernero; John Kidd; Shahina Pardhan

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 595. doi:

Influence of Wavefront Aberration Order on Vision Prediction and Correction Open Access

Kathryn Lynn Kosteva; Rosalyn Angela Lilienthal; Jos J Rozema; Christopher Taylor; David Rio

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 596. doi:

Optical adaptation to spherical aberration Open Access

Fan Yi; Michael J Collins; Brett A Davis

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 597. doi:

Isolated human crystalline lens spherical aberration: Experimental measurements and predictions from OCT-based geometry Open Access

Ashik Mohamed; Siobhan Williams; Eduardo Martinez-Enriquez; Alberto De Castro; Marco Ruggeri; Bianca Maceo Heilman; Yu-Cherng Chang; N. Geetha Sravani; Cornelis Rowaan; Alex Gonzalez; Shravya Sri Durgam; Arthur Ho; Robert C Augusteyn; Jean-Marie Parel; Susana Marcos; Fabrice Manns

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 598. doi:

Comparison of curvature-based and biometry-based methods for in vivo crystalline lens power calculation Open Access

Gabrielle Monterano Mesquita; Yu-Cherng Chang; Florence Cabot; Siobhan Williams; Giovanni Gregori; Arthur Ho; Marco Ruggeri; Sonia H Yoo; Jean-Marie Parel; Fabrice Manns

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 599. doi:

Inter-subject variability of through-focus visual acuity with induced spherical aberration Open Access

Eloy A. Villegas; Lucía Hervella; Pablo Artal

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 600. doi:

Testing the effect of ocular aberrations on perceived Transverse Chromatic Aberration Open Access

SARA AISSATI; Maria Vinas; Clara Benedi-Garcia; Carlos Dorronsoro; Susana Marcos

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 601. doi:

Towards better visual image quality metrics for real world conditions Open Access

Gareth Hastings; Jason D Marsack; Raymond A Applegate

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 602. doi:

Extremely high resolution ocular aberrometry up to 2.4 million points Open Access

Sergio Bonaque-González; José Manuel Rodríguez-Ramos; Juan Manuel Trujillo-Sevilla; Oscar Casanova-González; David Carmona-Ballester; Miguel Jesús Sicilia-Cabrera

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 603. doi:

Objective determination of visual acuity from a single wavefront measurement Open Access

Daniel R Neal; Thomas Daniel Raymond; Wei Xiong; Derek Nankivil

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 604. doi:

Adaptive-optics vision simulation of multifocal lenses for myopia progression Open Access

Shrilekha Vedhakrishnan; Maria Vinas; SARA AISSATI; Clara Benedi Garcia; Mercedes Romero; Ana Gonzalez-Ramos; Carlos Dorronsoro; Susana Marcos

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 605. doi:

Phase perception altered by long-term neural adaptation to habitual optics reduces neural binocular summation Open Access

Geunyoung Yoon; Cherlyn Joan Ng; Duje Tadin; Randolph Blake; Martin S Banks

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 606. doi:

Aberration estimation by computational adaptive optics to improve the quality of images containing structured illumination Open Access

Jyoti Paul; Andrew J Lambert

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 607. doi:

Wavelength Optimization of the Retinal Image Quality Open Access

Jesson Martin; Shantel Nunez

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 608. doi:

The rabbit lens – a bionic extended depth of focus device? Open Access

Thomas Stahnke; Sebastian Bohn; Heinrich Stolz; Rudolf F Guthoff; Oliver Stachs; Karsten Sperlich

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 609. doi:

Crystalline lens Gradient Index Profile in the guinea pig myopia model Open Access

Susana Marcos; Alberto De Castro; Eduardo Martinez-Enriquez; Pablo Perez-Merino; Miriam Velasco-Ocana; Luis Revuelta; Sally A McFadden

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 610. doi:

Applying Retinal Image Simulations to the Marmoset Eye for Emmetropization Studies Open Access

Mateusz Tomasz Jaskulski; Rita Nieu; Xiaoying Zhu; Alexandra Benavente-Perez

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 611. doi:

Preliminary Analysis of a Novel Software-Based Method of Quantifying Metamorphopsia: A Pilot Study Open Access

Jacob Lifton; Andrew A Moshfeghi

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 612. doi:

Protection of retinal ganglion cells by kynurenic acid Open Access

Rooban Nahomi; Mihyun Nam; Johanna Rankenberg; Stefan Rakete; Mina B Pantcheva; Dorota L Stankowska; Julie Houck; Ginger Johnson; Paul MacLean; Ram H Nagaraj

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 614. doi:

IGFBPL1 protects against the neuronal and vision loss in IGFBPL1^-/- mice with ocular hypertension Open Access

Kin-Sang Cho; Xin Wei; Dong Feng Chen

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 615. doi:

Upregulation of retinal gap junction protein Cx36 expression in glaucoma is mediated by reducing LNX2 degradation of Cx36 Open Access

Xinbo Li; Yi Wang; Xiaomin Zhao

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 616. doi:

Conditional TRPV4 ablation inhibits pressure-induced retinal inflammation in mouse glaucoma Open Access

Monika Lakk; Felix Vazquez-Chona; Oleg Yarishkin; David Krizaj

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 617. doi:

Treatment with p38 Inhibitor BIRB 796 is Neuroprotective in Models of Glaucoma Open Access

Wendi S Lambert; Silvia Pasini; Cathryn R Formichella; Purnima Ghose; Victoria Vest; Brian Carlson; Vincent Yao; David J Calkins

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 618. doi:

PKA inhibition protects optic nerve head astrocytes by modulating Akt/Bax phosphorylation and Mfn1/2 oligomerization against oxidative stress Open Access

Wonkyu Ju; Myoung Shim; Keunyoung Kim

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 619. doi:

The Lipoxin LXB₄ Reduces Mitochondrial Oxidative Stress in Retinal Ganglion Cells Open Access

izhar Livne-bar; John G Flanagan; Karsten Gronert; Jeremy M Sivak

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 620. doi:

Analysis of extracellular vesicles released by Müller glial cells in vitro. Open Access

William Lamb; Karen Eastlake; Gareth Williams; Peng Tee Khaw; G. Astrid Limb

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 621. doi:

Upregulation of monocarboxylate transporter 2 protects retinal ganglion cells in glaucoma Open Access

Nate Pappenhagen; Mohammad Harun-Or-Rashid; Assraa Jassim Jaboori; Denise M Inman

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 622. doi:

Effect of ripasudil on NMDA-induced retinal damage in mouse eye. Open Access

Reiko Yamagishi; Megumi Honjo; Makoto Aihara; Chui Yong Ku

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 623. doi:

The effect of GDF15 on the neurite outgrowth in retinal ganglion cells. Open Access

Yuki Iwata; Satoshi Inagaki; Wataru Morozumi; Shinsuke Nakamura; Masamitsu Shimazawa; Hideaki Hara

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 624. doi:

Adenosine A3 receptor agonist prevents the loss of retinal ganglion cells in a glaucoma model Open Access

Raquel Boia; Manuel Salinas-Navarro; Alejandro Gallego-Ortega; Caridad Galindo-Romero; Marta Agudo-Barriuso; Antonio F Ambrosio; Manuel Vidal-Sanz; Ana Raquel Santiago

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 625. doi:

Donepezil, an anti-Alzheimer's disease drug has the neuroprotective effect on RGCs derived from familial glaucoma patients’ iPS cells. Open Access

Satoshi Inagaki; Michinori Funato; Shinsuke Nakamura; Masamitsu Shimazawa; Hideo Kaneko; Hideaki Hara

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 626. doi:

Telmisartan, an angiotensin II type 1 receptor blocker, reduces IOP and prevents axon loss in mice with experimental glaucoma Open Access

Ralph J Hazlewood; John Kuchtey; Rachel W Kuchtey

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 627. doi:

FK506 treatment promotes neuroprotection in organ transplanted glaucoma patients: a retrospective chart review. Open Access

Valentina Reffatto; Tamila Williams; Mary Schmitz-Brown; Praveena K. Gupta; Gianmarco Vizzeri

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 628. doi:

Proteomic Approaches to Study Cell Death Mechanisms in Human Stem Cell-Derived Retinal Ganglion Cells Open Access

Joseph L Mertz; Xitiz Chamling; David J Clark; Kyung Cho Cho; Cynthia Berlinicke; Hui Zhang; Donald J Zack

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 629. doi:

The effect of mobile zinc on retinal ganglion cells death after glaucomatous optic nerve injury Open Access

Zhe Liu; Li Yangjiani; Yunan Wei; Jingfei Xue; Yehong Zhuo; Yiqing Li

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 630. doi:

Evaluating iron chelation for retinal ganglion cell protection in mouse models of glaucoma Open Access

Albert Bargoud; Qi Cui; Ahmara Gibbons Ross; Ying Song; Joshua L Dunaief

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 631. doi:

Sub-lethal hypoxic damage promotes primary retinal ganglion cell survival and VEGF may play an essential role Open Access

Wungrak Choi; Ah Reum Hwang; Hyoung Won Bae; Jun Mo Lee; Gong Je Sung; Chan Y Kim

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 632. doi:

Deficiency of ALX/FPR2 Deteriorates Inner Retinal Injury in Experimental Chronic Ocular Hypertension Open Access

John G Flanagan; Karsten Gronert; Jeremy M Sivak; Paul Cullen; Hsin-Hua Liu

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 633. doi:

Human Umbilical Cord Mesenchymal Stem Cells protect against ocular hypertension induced retinal injury via toll-like receptor 4 (TLR4) pathway Open Access

Shangli Ji; Jie Xiao; Zhiyuan LI; Shibo Tang

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 634. doi:

Novel Modulation of Endogenous Tau protein by Shp2 tyrosine Phosphatase in the Retina Open Access

Vivek Kumar Gupta; Nitin Chitranshi; Kanishka Pushpitha; Mehdi Mirzaei; Stuart L Graham

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 635. doi:

siRNA Downregulation of RhoA Expression Reduces Apoptosis of Oxidative Retinal Ganglion Cells Open Access

Qian Liu; Haijun Li; Changgeng Liu

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 636. doi:

Creating Gene Therapy With SIRT1 Signaling for Neuro-protection in Optic Nerve Disease Open Access

Ahmara Gibbons Ross; Devin McDougald; Reas Sulaimankutty; Kimberly Dine; Kenneth S Shindler

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 637. doi:

Ocular Hypertension Model Induced by Episcleral Vein Cauterization for Screening Retinal Ganglion Cells Neuroprotection Therapies in Brown Norway Rats Open Access

Lichun Zhong

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 638. doi:

A novel model of experimental glaucoma in the marmoset Open Access

Stewart A Bloomfield; Sandeep Kumar; Alexandra Benavente-Perez; Suresh Viswanathan; Abram Akopian

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 639. doi:

Highly Accurate, Fully-Automated Batch Processing of Retinal Ganglion Cell Counts from Retinal Flatmounts Open Access

Robert James Casson; Chelsea Guymer; Glyn Chidlow; John P M Wood; Lloyd Damp

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 640. doi:

Protects effects of edible plant, Lithospermum erythrorhizon on oxidative stress-induced retinal degeneration in vitro and in vivo Open Access

Sang Hoon Jung; Tae Kyeom Kang; Kyung-A Kim; Wook Bin Lee; Young Joo Kim; Je Hyeong Jung; Sung Jae Yang; Tae-Jin Kim

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 642. doi:

The Effects of KR-67607 on Intraocular Pressure and Glaucomatous Optic Neuropathy Open Access

Jee Young Kim; Yunjeong Kang; Yerin Shin; Eunyoung Park; Jin Soo Lee; Jaewook Yang

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 643. doi:

Electical Fields Direct Retinal Ganglion Cell Axon Growth Open Access

Kimberly Gokoffski; Min Zhao

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 644. doi:

Optimization of trabecular meshwork laser strategy to achieve sustained 2-3X intraocular pressure elevation and glaucomatous optic neuropathy in primates Open Access

Wenzheng Hu; Chintan Patel; Jamila Martin; Vernard Woodley; Jordan Attwood; Tatiana Corey; Merissa O'connor; Matthew S Lawrence

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 645. doi:

Activity-dependent molecular programs for optic nerve regeneration Open Access

Qing Wang; Irene Harutyunyan; S. Thomas Carmichael

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 646. doi:

Survival of αRGC and ipRGC in a mouse model of glaucoma Open Access

Sari Miyachi Honda; Kazuhiko Namekata; Atsuko Kimura; Xiaoli Guo; Akira Matsuda; Akira Murakami; Takayuki Harada

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 647. doi:

All classes of melanopsin-expressing retinal ganglion cells are protected from degeneration in early ocular hypertension Open Access

Yang Zhang; Ashish Bhandari; Andrew Stothert; Jennie C. Smith; Matthew J Van Hook

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 648. doi:

Timeline of retinal ganglion cell loss and complement response in βb1-CTGF glaucoma mice Open Access

Sabrina Reinehr; Johanna Dörner; Dennis Koch; Christina Voss; Rudolf Fuchshofer; Burkhard Dick; Stephanie C Joachim

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 649. doi:

POU6F2 modulates corneal thickness and susceptibility to injury in directionally selective on-off retinal ganglion cells Open Access

Eldon E Geisert; Rebecca King; Ying Li; Jiaxing Wang

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 650. doi:

Exploring the Role of BAX in the Degeneration of Retinal Ganglion Cell Axons and Dendritic Arbors Open Access

Ryan Joseph Donahue; Briana N. Ebbinghaus; Mrinalini Hoon; Robert W Nickells

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 651. doi:

Methods to improve and quantify retinal integration of transplanted stem cell-derived retinal ganglion cells for optic nerve regeneration Open Access

Thomas Vincent Johnson; Caitlyn Tuffy; Joseph L Mertz; Harry A Quigley; Donald J Zack

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 652. doi:

mTOR Signaling and Human Retinal Ganglion Cell Development and Function Open Access

Pooja Teotia; Matthew J Van Hook; Iqbal Ahmad

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 653. doi:

Switching from the proteasomal to the lysosomal pathway for MQC during human RGC differentiation is essential for RGC survival Open Access

Arupratan Das; Claire Wenger; Cindy Berlinicke; Nicholas Marsh-Armstrong; Donald J Zack

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 654. doi:

Deletion of Aqp9 in mice enhances retinal ganglion cell death after optic nerve injury Open Access

Sotaro Mori; Takuji Kurimoto; Akiko Miki; Sentaro Kusuhara; Makoto Nakamura

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 655. doi:

Downstream transcriptional control of retinal ganglion cell apoptosis after axonal injury Open Access

Stephanie B. Syc-Mazurek; Hongtian Yang; Gareth R Howell; Richard T Libby

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 656. doi:

Neuronal Nogo-A upregulation promotes retinal ganglion cell axon dystrophy: a new mechanism underlying glaucoma-induced optic nerve axonopathy? Open Access

Léa Rodriguez; Sandrine Joly; Julius Baya Mdzomba; Deniz Dalkara; Vincent Pernet

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 657. doi:

Wld^S gene protects against deficits in visual acuity and axonal transport caused by ocular hypertension Open Access

Silvia Pasini; Michael L Risner; Melissa Cooper; Wendi S Lambert; Karis B D'Alessandro; David J Calkins

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 658. doi:

Loss of mature oligodendrocytes after chronic intraocular pressure elevation in the PTP-Meg2 glaucoma mouse model Open Access

Jacqueline Reinhard; Susanne Wiemann; Maximilian Wulf; Stephanie Carolin Joachim; Andreas Faissner

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 659. doi:

Mechanisms underlying early-stage changes in cellular function of optic nerve head astrocytes and retinal ganglion cells during oxidative stress as novel targets for neuro- and glioprotec... Open Access

Peter Koulen; John Means; R. Scott Duncan

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 660. doi:

Endothelin Signaling in Glaucomatous Neurodegeneration Open Access

Olivia J Marola; Stephanie B Syc-Mazurek; Gareth R Howell; Richard T Libby

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 661. doi:

Extracellular Matrix Tissue Content of the Neuroretinal Rim differs in Healthy and Glaucomatous Eyes Open Access

Nimesh Bhikhu Patel; Louvenia Carter-Dawson; Ronald S Harwerth

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 662. doi:

Loss of optineurin disrupts mitochondrial networks and morphology Open Access

Henry Tseng; Emily Sun; James Powers; Charlaine Chen

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 663. doi:

Developmental Regulation of Mitochondrial Axonal Transport in Rat Retinal Ganglion Cells Open Access

Satoshi Yokota; Sahil Shah; Jeffrey L Goldberg

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 664. doi:

Mice with mutation of the mitochondrial gene cytochrome c oxidase 1 have impaired visual function and retinal ganglion cell loss Open Access

Qi N Cui; Albert Bargoud; Ying Song; Kiersten N Keller; Deborah G Murdock; Joshua L Dunaief; Douglas C Wallace

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 665. doi:

Short-term Cerebrospinal Fluid Pressure Reduction Model Mimic Optic Neuropathy Disease ——Beijing Intracranial and Intraocular Pressure (iCOP) Study Open Access

Ningli Wang; Xiaoxia Li

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 666. doi:

Glaucoma-associated E50K-optineurin mutation impairs mitochondrial-derived vesicle trafficking Open Access

James Powers; Kayla Trautman-Buckley; Emily Sun; Charlaine Chen; Denise M Inman; Henry Tseng

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 667. doi:

Human primary retinal cells as an in-vitro cell culture model for investigating defective signalling caused by OPTN mutants associated with glaucoma Open Access

Zuberwasim Sayyad; Sushma Vishwakarma; Tarjani Vivek Dave; Inderjeet Kaur; Radha Vegesna; Ghanshyam Swarup

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 668. doi:

Pre-degenerative Accumulation of Superoxide and Hydroxide in a Chronic Mouse Model of Glaucoma Open Access

Assraa Hassan Jassim; Denise M Inman

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 669. doi:

Frequent non-intact axons and extensive extracellular debris in the optic nerve head at very early stages of non-human primate experimental glaucoma Open Access

Nicholas Marsh-Armstrong; Catherine Hou; Cheri Stowell; Imee Williams; Eric Bushong; Howard Lockwood; Juan Reynaud; Mark Ellisman; Claude F Burgoyne

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 670. doi:

Live imaging of debris clearance in the optic nerve of Xenopus laevis Open Access

Lindsay Fague; Alexandra Mikhailova; Nicholas Marsh-Armstrong

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 671. doi:

Microglial activation and interaction at synaptic sites in experimental glaucoma. Open Access

Alfred K Yu; Kelly Mai; Esther Choe; Alan Tran; Luca Della Santina; Yvonne Ou

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 672. doi:

Neuro-inflammation and degeneration in the Optic Nerve Head (ONH) in a Genetic Feline Model of Glaucoma Open Access

Kazuya Oikawa; Julie A Kiland; N.Matthew Ellinwood; Gillian J McLellan

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 673. doi:

Increased infiltration of immune cell subsets and altered soluble factor profile in aqueous humor of glaucoma patients correlates with disease severity Open Access

Archana Padmanabhan Nair; Ganesh Ram Sahu; Sushma Tejwani; Arkasubhra Ghosh; Swaminathan Sethu

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 674. doi:

Elevated Intraocular Pressure (IOP) Induced Optic Nerve Head (ONH) Gene Expression Responses: Two Experimental Models and Two Analysis Platforms Open Access

Diana C Lozano; Hari Jayaram; Tiffany Choe; William Cepurna; Shandiz Tehrani; Elaine Johnson; John C Morrison

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 675. doi:

Correlation between RGC loss and optic nerve crush force impulse in mice established with an instrumented forceps Open Access

Xiaorong Liu; Liang Feng; Ishan Shindi; John B Troy; Laxman Saggere

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 676. doi:

A novel inducible and reversible mouse glaucoma model: Silicone Oil-Induced Ocular Hypertension Under-detected (SOHU) Open Access

Jie Zhang; Liang Li; Haoliang Huang; Hannah Webber; Shaohua Li; Peter Hao Tang; Vinit B Mahajan; Yang Sun; Mingchang Zhang; Yang Hu

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 677. doi:

Strain associated responses to experimental glaucoma induced by injection of microspheres into the anterior chamber of the rat eye. Open Access

Karen Eastlake; Hari Jayaram; Weixin Wang; William Lamb; Celia Murray-Dunning; Peng Tee Khaw; G. Astrid Limb

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 678. doi:

Automated analysis of axons and glia in a Brown Norway rat model of glaucoma, comparison of QuPath to AxonJ Open Access

Barbara A Mysona; Sharmila Segar; Jing Zhao; Kathryn E Bollinger

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 679. doi:

Serum autoantibody biomarkers of neuroinflammation and neurodegeneration in glaucoma Open Access

Daniel M. Vu; Mulugu V. Brahmajothi; Mohamed B. Abou-Donia; Henry Tseng

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 680. doi:

Drebrin plasma levels elevated with RGCs axonopathy in glaucoma patients Open Access

GAN YIJING; ZAILONG CHI; JIA QU

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 681. doi:

Role of Central Insulin Resistance in Glaucoma Open Access

Muneeb Ahmad Faiq; Tanuj Dada; Trina Sengupta; Madhu Nath; Thirumurthy Velpandian; Kevin Chan

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 682. doi:

Glucocorticoid-induced glaucomatous neurodegeneration is associated with demyelination of optic nerve axons and infiltration of immune cells. Open Access

prabhavathi maddineni; Ramesh Kasetti; Pinkal D Patel; Gulab Zode

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 683. doi:

Prediction for Effectiveness of Unilateral Selective Laser Trabeculoplasty for the Untreated Fellow Eye of Primary Open-angle Glaucoma Patients Open Access

Xiang Fan; Lingling Wu

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 684. doi:

Do Concurrent Topical Medications Influence the Extent of IOP Reduction with SLT? Open Access

Madeleine Puig; Mario Montelongo; William Eric Sponsel

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 685. doi:

Outcomes of selective laser trabeculoplasty after prior incisional surgery for open-angle glaucoma Open Access

Connie M Wu; Brandon Kuley; Cindy X Zheng; Michael Lin; Stephen J Moster; Courtland Schmidt; Marlene Moster; Michael J Pro; Daniel Lee

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 687. doi:

West Indies Glaucoma Laser Study (WIGLS) 6. Factors Associated With 3-Year Treatment Success Using Selective Laser Trabeculoplasty in Afro-Caribbean Patients with Open-Angle Glaucoma Open Access

Balasubramani K Goundappa; Darra Burt; Hazel Shillingford-Ricketts; Tony Realini

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 688. doi:

Outcomes of repeat selective laser trabeculoplasty for open-angle glaucoma Open Access

Saumya Copparam; Brandon Kuley; Cindy X Zheng; Michael Lin; Stephen J Moster; Courtland Schmidt; Marlene Moster; Daniel Lee; Michael J Pro

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 689. doi:

Is Capacity for Normalization of Optic Nerve Function After Selective Laser Trabeculoplasty Dependent on Degree of Retinal Nerve Fiber Layer thinning, Optic Nerve Head Cupping, or Hyperte... Open Access

Sabrina Chen; Lynnette Nguyen; Anvi Brahmbhatt; Keshav Narain

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 690. doi:

Is Severity of Glaucomatous Visual Field Loss Associated with Short-term IOP Lowering Effect of SLT? Open Access

Mario Montelongo; Rick Trevino; William Eric Sponsel

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 691. doi:

A Retrospective Chart Review Comparing Efficacy of Selective Laser Trabeculoplasty applied to 360 degrees vs 180 degrees of the angle. Open Access

Abraham Nirappel; David Sola-Del Valle

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 692. doi:

Comparison between nasal and temporal 180-degree selective laser trabeculoplasty in open-angle glaucoma: short-term results Open Access

Jayter Silva Paula; Cassia Senger; C Gustavo De Moraes; Maria de Lourdes Rodrigues

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 693. doi:

Laser in Glaucoma and Ocular Hypertension Trial (LIGHT) in China -An Unmasked, Pragmatic Randomized Controlled Trial: Design and Baseline Characteristics Open Access

Yangfan Yang; Yuzhen Jiang; Mingkai Lin; Xing Liu; Yanmei Fan; Neil Nathwani; Pingping Liu; Jingjing Huang; Yunlan Ling; Yi Min Zhong; Xiulan Zhang; Yehong Zhuo; Gus Gazzard; Minbin Yu

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 694. doi:

Assessing the effectiveness of PASCAL Laser Trabeculoplasty in the management of glaucoma Open Access

Syed Naqib Ahmed; Syed Mohammed Shahid; Sam Kanavati; Syed Ahmed; Julian Hickman-Casey

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 695. doi:

Efficacy of Micropulse Laser Trabeculoplasty in Open Angle Glaucoma Open Access

antonella clemente; Caterina Toma; Stela Vujosevic; chiara padovan; stefano de cillà

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 696. doi:

Post-operative one hour intraocular pressure spikes and long term pressure efficacy in micropulse laser trabeculoplasty (MLT) vs selective laser trabeculoplasty (SLT) Open Access

Catherine Thomas; Dana Darwish; Michael Giovingo; Amar Mannina

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 697. doi:

Efficacy and safety of transscleral micropulsed laser in the treatment of glaucoma refractory to treatment Open Access

Lucia Delgadillo; Gian Franco Diez; José Francisco Ortega

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 698. doi:

Short-term outcomes of MicroPulse Trans-scleral Cyclophotocoagulation in Korean patients Open Access

Jaekeun Chung; Jong Jin Jung; Young Cheol Yoo

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 699. doi:

Micropulse Transscleral Cyclophotocoagulation in Refractory Glaucoma. 6 month follow-up. Open Access

Clarisa Del Hierro; Daniela Alvarez Ascencio; Carolina Prado Larrea; Jesús Jiménez Román

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 700. doi:

Pilot Study Comparing Transscleral Cyclophocoagulation in Chinese using Short and Long Duration Protocol Open Access

Jonathan Chan; Ivan Chow

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 701. doi:

Outcomes of MicroPulse Cyclophotocoagulation in Adult Glaucoma Patients Open Access

Eric Grisham; Sara Hooshmand; Jella Angela An

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 702. doi:

The Efficacy and Safety of Micropulse Photocyclophotocoagulation in the Treatment of Refractory Advanced Pediatric Glaucomas Open Access

Bibiana Jin Jin Reiser

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 703. doi:

Three-Year Retrospective Study of Treatment with Micropulse Cyclophotocoagulation as a Primary Procedure for Neovascular Glaucoma Open Access

Brett Breshears; Thomas D Patrianakos; Michael Giovingo

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 704. doi:

Intraocular pressure reduction profile in patients with refractory glaucoma submitted to micropulse transscleral cyclophotocoagulation Open Access

Larissa Ibrahim; Ariel Chaves; Tereza Kanadani; Syril Dorairaj; Tiago Prata; Fabio Kanadani

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 705. doi:

Pars plicata versus pars plana application of micropulse transscleral cyclophotocoagulation Open Access

Sören Waibel; Robert Herber; Lutz E Pillunat; Karin R Pillunat

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 706. doi:

Efficacy of Transcleral Diode Cyclophotocoagulation in a sub-Saharan Rural Population with Severe Glaucomatous Ocular Hypertension Open Access

vincent Mkwezgalamba saka; Richard Chitedze; Scott Sullivan; Abha Amin; Mario Montelongo; William Eric Sponsel

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 707. doi:

Effectiveness of Laser Goniopuncture as an Adjuvant Therapy to Non-Penetrating Deep Sclerectomy for Lowering Intraocular Pressure Open Access

Scott Sullivan; Abha Amin; Mario Montelongo; William Eric Sponsel

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 708. doi:

Bubble-Free Gonioscopy II Open Access

Frederick M Kapetansky; Nathaniel B Dusseau

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 709. doi:

Incidence and features of uveal melanoma in a closed, managed care USA population Open Access

Gena Damento; Ronald B Melles; Isabella Phan; Michael I Seider

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 710. doi:

Scope of Retinal Disease-Related Inpatient Ophthalmology Consultations at a National Cancer Institute Designated Comprehensive Cancer Center. Open Access

M. Ali Khan; Philip P. Le; Alex Huang; Olivia L Lee; John A Irvine

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 711. doi:

Clinicopathologic Features of Rare Non-Pigmented Ciliary Body Adenomas: a case series and literature review Open Access

Richard K Lee; Elaine Han; Peng Lu; Jinrui Ma; Pedro Monsalve; Sander Dubovy

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 712. doi:

Clinicopathological evaluation of eye removal procedures: a 13-year evaluation Open Access

Vinicius Carriero Lima; Gabriela Cavalieri; Ana Beatriz Toledo Dias; Christina Mastromonaco; Sabrina Bergeron; Julia Burnier; Miguel N Burnier

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 713. doi:

A numerical model to calculate the role of the vitreous humor viscosity in laser-induced thermal damage in choroidal melanomas Open Access

Alcides Fernandes; Olga Pinheiro Garcia; Virginia Laura Lucas Torres; Paulo Roberto Maciel Lyra; Rita de Cássia Fernandes de Lima

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 714. doi:

Fractionated Stereotactic Radiosurgery for Very Large (T4) Posterior Uveal Melanoma(UM): 1-year and 2-year Results Open Access

Alexander de Castro-Abeger; Diandra N. Ayala-Peacock; Guozhen Luo; Gregory Twork; Anthony Daniels

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 715. doi:

Treatment of uveal melanoma located at the ciliary body using a robotic assisted linear accelerator Open Access

Raffael Liegl; Christoph Fuerweger; Maren Schmeinck; Jakob Siedlecki; Alexander Muacevic; Ulrich Schaller; Siegfried Priglinger; Paul Foerster

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 716. doi:

"Doughnut" shaped braquitherapy plaque for the treatment of Iris melanoma Open Access

Vidal Soberón; Yuoming Yang; James Lamb; Philip E Chow; Tara A McCannel

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 717. doi:

Two year results of a phase 1b/2 open-label clinical trial of AU-011 for the treatment of small to medium choroidal melanoma Open Access

Tara A McCannel; Abdhish Bhavsar; Antonio Capone; Hakan Demirici; Ivana K Kim; Brian Marr; Cadmus Rich; Amy C Schefler; Carol L. Shields

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 719. doi:

Blue wave fundus autofluorescence imaging following ruthenium-106 brachytherapy for choroidal melanoma Open Access

Almut Bindewald-Wittich; Thomasz Swenshon; Eva Carasco; Gregor D Willerding

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 720. doi:

Prophylactic Intravitreal Bevacizumab after Plaque Radiotherapy for Uveal Melanoma: Analysis of 1311 Eyes of 1310 Patients by Age Open Access

Michael Chang; Lauren A Dalvin; Li-Anne S Lim; Mehdi Mazloumi; Antonio Yaghy; Arman Mashayekhi; Carol L. Shields

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 721. doi:

Randomized Trial of Monthly versus PRN intravitreal injection of ranibizumab with and without PRN targeted panretinal photocoagulation (TRP) for radiation-induced macular edema: RRR Two y... Open Access

Amy C Schefler; Rajiv Anand; Timothy Fuller; Dwain Fuller; Ryan S Kim

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 722. doi:

Ryan Kim; Rajiv Anand; Dwain Fuller; Timothy Fuller; Maria Bretana; Amy C Schefler

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 723. doi:

Serous Pigment Epithelial Detachments Associated with Choroidal Nevi Open Access

Kirk Kohwa Hou; Vidal Soberón; Tara A McCannel

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 724. doi:

Photoreceptor Morphology and Correlation with Subretinal Fluid Chronicity Associated with Choroidal Nevus Open Access

Antonio Yaghy; Lauren A Dalvin; Michael Yu; Mehdi Mazloumi; Carol L. Shields

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 725. doi:

Decreased retinal sensitivity overlying melanocytic choroidal lesions evaluated by microperimetry Open Access

Rodrigo Jorge; Marina Labarrere; Andre Messias; Zelia Correa

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 726. doi:

Quantitative autofluorescence characteristics of choroidal nevi Open Access

Marco Mazzola; Ekaterina Semenova; Wei Wei; R Theodore Smith; Paul T. Finger

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 727. doi:

The SON Study: preliminary results from the Italian series Open Access

Veronica Forlani; Chiara Preziosa; Adrian Tien-Chin Fung; Giovanni Staurenghi; Alessandro Invernizzi; Marco Pellegrini

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 728. doi:

Phenotypic plasticity in uveal melanoma spheroids Open Access

Helen Kalirai; Luna Djirackor; Sarah E Coupland

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 729. doi:

A 3D spheroid model of Uveal Melanoma (UM) Open Access

Luna Djirackor; Haleh Shahidipour; Sarah E Coupland; Helen Kalirai

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 730. doi:

Characterization of uveal melanoma cell lines grown in three-dimensional culture systems Open Access

Alicia Alejandra Goyeneche; Jade Lasiste; Prisca Bustamante; Julia Burnier; Miguel N Burnier

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 731. doi:

The effect of spliceosome inhibitor E7107 on SF3B1^mutuveal melanoma cell lines Open Access

Wojtek Drabarek; Job van Riet; Harmen van de Werken; Annelies de Klein; Emine Kilic

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 732. doi:

Blockade of MDM2 Nuclear Localization Signal as a Novel Anti-Metastatic Therapeutic Approach Open Access

Andrew Irvine; Zachary K. Goldsmith; Caroline Awh; Vanessa Marie Morales; Matthew W Wilson

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 733. doi:

Infectious knockdown of CREB and HIF-1 for the treatment of metastatic uveal melanoma Open Access

Shahar Frenkel; Ana Voropaev; Maria Gimmelshein; Dudi Shneor; Alik Honigman

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 734. doi:

Cell population having a resistance to melanoma antigen specific T cell in uveal melanoma Open Access

Kinya Tsubota; Yoshihiko Usui; Hiroshi Goto

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 735. doi:

Inflammatory profile of human choroidal nevi Open Access

Melissa Therese Wegkamp; Martine J Jager; Madeleine Vader; Michele C Madigan

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 736. doi:

Influence of GNAQ or GNA11 mutations on HLA expression in Uveal Melanoma Open Access

Christiaan Weeghel; Annemijn Philine Annette Wierenga; Mieke Versluis; Gregorius P.M. Luyten; Martine J Jager

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 739. doi:

Soluble HLA in the aqueous humour as risk factor or a marker of inflammation in uveal melanoma Open Access

Annemijn Philine Annette Wierenga; Gulcin Gezgin; Els van Beelen; Michael Eikmans; Mieke Versluis; Robert M. Verdijk; Sjoerd van Duinen; Marina Marinkovic; Gregorius P.M. Luyten; Martine J Jager

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 740. doi:

Regulation of PD-L1 in uveal melanoma Open Access

Zahra Souri; Annemijn Philine Annette Wierenga; Marijke Spruyt-Gerritse; Michael Eikmans; Martine J Jager

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 741. doi:

Efficacy of immune checkpoint inhibitors for treating uveal melanoma metastases Open Access

Monica Oxenreiter; Anne Marie Lane; Justine V Cohen; Ryan J Sullivan; Ivana K Kim; Evangelos S Gragoudas

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 742. doi:

Intraocular metastases development in patients undergoing cancer immunotherapy: a cautionary tale Open Access

Martina Angi

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 743. doi:

Beta-blocker: a potential adjuvant therapy for Uveal Melanoma Open Access

Eva Jin; Prisca Bustamante; Denise Miyamoto; Jade Lasiste; Alicia Alejandra Goyeneche; Miguel N Burnier; Julia Burnier

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 744. doi:

The Role of Cytosine-5 RNA Methylation in Regulating Uveal Melanoma Cell Proliferation and Migration Open Access

Dongsheng Yan; Guangying Luo; Yunping Zhao; Dan-Ning Hu

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 745. doi:

Cancer stem cells markers in primary uveal melanoma Open Access

Isabela Vianello Valle; Matthew Kondoff; Alex Laskaris; Tadhg Ferrier; Sabrina Parent; Julia Burnier; Miguel N Burnier

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 746. doi:

Validation of Choroid from Uveal Melanoma Eyes as Control Tissue for Proteomic Studies Open Access

Geeng-Fu Jang; Jack S Crabb; Bo Hu; Belinda Willard; Helen Kalirai; Arun D Singh; Sarah E Coupland; John W Crabb

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 747. doi:

Using Mass-Cytometry approach for the characterisation of the microenvironment of primary uveal melanoma. Open Access

Carlos Rogerio De Figueiredo; Helen Kalirai; Joseph Sacco; Judy Coulson; Sarah E Coupland

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 748. doi:

Prognostication of uveal melanoma patients: are exosomes the solution? Open Access

Emine Kilic; Kyra Smit; Natasha van Poppelen; Taran Lunavat; Jolanda Vaarwater; Su Chul Jang; Robert M. Verdijk; Jan Lötvall; Annelies de Klein

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 749. doi:

BAP1 Immunoreactivity correlates with gene expression class in uveal melanoma Open Access

Hans E Grossniklaus; Thonnie R See; Gustav Stalhammar; Stephen S Phillips

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 750. doi:

Digital image analysis of BAP-1 accurately predicts uveal melanoma metastasis Open Access

Gustav Stålhammar; Thonnie Rose See; Stephen S Phillips; Hans E Grossniklaus

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 751. doi:

Next-generation sequencing of uveal melanoma for detection of genetic alterations predicting metastasis Open Access

Armin R Afshar; Bertil E Damato; Jay M Stewart; Ritu Roy; Adam Olshen; Boris Bastian

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 752. doi:

Transcriptomic analysis reveals genes and miRNAs dysregulated in high risk primary uveal melanoma. Open Access

Karen Aughton; Sarah L Lake; Louise Takeshita; Francesco Falciani; Helen Kalirai; Sarah E Coupland

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 753. doi:

MiR-34a regulates the migration and invasion of Uveal Melanoma cells through modulating LGR4 Open Access

Qiang Hou; Lili Tu

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 754. doi:

Promoter methylation of RASSF1 is common in non-tumor choroid tissue Open Access

Sabrina Yasmin Bulas; Saurabh Pancholi; James Massengill; Frederick Davidorf; Colleen M Cebulla; Mohamed H Abdel-Rahman

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 755. doi:

Methylation Clustering in Uveal Melanoma Open Access

Tadhg Ferrier; Prisca Bustamante; Thupten Tsering; Eva Jin; Paulina Garcia de Alba Graue; Julia Burnier

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 756. doi:

Expression of cysteinyl leukotriene receptors 1 and 2 in uveal melanoma Open Access

Paulina Garcia de Alba Graue; Alicia Goyeneche; Jacqueline Coblentz; Tadhg Ferrier; Miguel N Burnier

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 757. doi:

Addressing Disparities in Hispanic Patients with Uveal Melanoma Using Global and Local Ancestry Analysis Open Access

Daniel Rodriguez; Margaret I Sanchez; Christina Decatur; J. William Harbour

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 758. doi:

Clinical, tumour, and family characteristics of uveal melanoma patients referred for analysis of potential underlying BAP1-tumour predisposition syndrome Open Access

Cindy Chau; Katya Afanasieva; Martine J Jager; Gregorius P.M. Luyten

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 759. doi:

Frequency of Mismatch Repair Gene Mutations in Uveal Melanoma Open Access

Christopher Brian Toomey; Samantha Phou; Kyle Fraser; Mathieu Bakhoum; John A Thorson; Bobby S Korn; Don Osami Kikkawa; Michael Henry Goldbaum; Jonathan H Lin

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 761. doi:

Secondary primary cancers in patients with uveal melanoma Open Access

Jens F Kiilgaard; Vanna Albieri; Karin Wadt; Klaus Kaae Andersen; Mette Marie Bagger

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 762. doi:

Multifarious evidence for NLRP3 inflammasome expression and activation in retinal pigment epithelium Open Access

Ivana Apicella; Shinichi Fukuda; Shuichiro Hirahara; Shaobin Wang; Siddharth Narendran; Nagaraj Kerur; Bradley Gelfand; Jayakrishna Ambati

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 765. doi:

Elevation of miR-155 induces a non-canonical inflammasome activation pathway in human retinal pigment epithelium (hRPE) Open Access

Congxiao Zhang; Arvydas Maminishkis; Kiyoharu miyagishima; Genqing Liang; Fnu Ruchi; Sheldon S Miller

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 766. doi:

Nod2 limits autoimmunity to the neuroretina through a T cell-intrinsic mechanism Open Access

Ellen J Lee; Ruth Napier; Emily Vance; Kimberly Samson; Sydney Lashley; Mary J Mattapallil; Justine R Smith; Rachel R Caspi; Holly Lallman Rosenzweig

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 767. doi:

The inflammasome pathway is activated in the retina of type 2 but not type 1 diabetic mice Open Access

Kevin Harkin; Mei Chen; Heping Xu; Sofia Pavlou

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 768. doi:

Application of the anti-inflammatory ocular neuropeptide alpha-melanocyte stimulating hormone (α-MSH) suppresses damage in retinas with ischemia/reperfusion Open Access

Andreas A Towers; Nayan Sanjiv; Tat Fong Ng; Amy CY Lo; Andrew W Taylor

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 769. doi:

miRNA profiles in exosomes from activated microglia – implication in retinal neuroinflammation Open Access

Chang Luo; Xiao Tang; Jian Liu; Shibo Tang; Heping Xu

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 770. doi:

Kinetics of the retinal microglial response to optic nerve injury Open Access

James Walsh; Robert N Weinreb; Dorota Skowronska-Krawczyk

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 771. doi:

Evaluation of the immune-microenvironment in retinal degeneration disease of RCS rat Open Access

Yuan Gao; Zhengqin Yin

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 772. doi:

Programmed Death Ligand 1 Protects Against Experimental Laser-Induced Choroidal Neovascularization in Mice Open Access

Xiaohong Wang; Hua Yan; Yunli Huang

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 773. doi:

Latent Ocular Murine Cytomegalovirus (MCMV) exacerbates the development of Choroidal Neovascularization (CNV) in VEGF-A^hyper mice Open Access

jinxian Xu; Xinglou Liu; Brendan Marshall; Zheng Dong; Ming Zhang

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 774. doi:

Age-related macular degeneration (AMD) like pathology in murine cytomegalovirus (MCMV) latently infected eyes of BALB/c mice following systemic neonatal infection Open Access

Ming Zhang; Xinglou Liu; jinxian Xu; Brendan Marshall; Zheng Dong

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 775. doi:

Changes of cytokine patters in the aqueous humor of neovascular age-related macular degeneration after 2 months of aflibercept treatment Open Access

Tomohito Sato; Masaru Takeuchi; Yoko Karasawa; Atsushi Tanaka; Toshio Enoki

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 776. doi:

Complement activation product levels in aqueous humor of patients with age-related macular degeneration. Open Access

Yutaka Kato; Tetsuju Sekiryu; Yasuharu Oguchi; Tomoko Omori; Takeshi Machida; Hideharu Sekine

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 777. doi:

Novel epitopes for anti-bestrophin autoantibodies in vitelliform macular dystrophy Open Access

Grazyna Adamus; Sufang Yang; Sten Andreasson; Elisabeth Wittstrom

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 779. doi:

Beclin-1 is Not Stimulated During Development of Experimental Murine Cytomegalovirus (MCMV) Retinitis in Mice with Retrovirus-Induced Immunosuppression (MAIDS) Open Access

Judee Grace Nemeño; Jessica Carter; Richard D Dix

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 780. doi:

Uveitic Retinal Pigment Epithelial cells do not suppress the phagocytic antigen processing pathways in antigen presenting cells Open Access

Tat Fong Ng; Isaac J Benque; Brandon S Lee; John Muus; Andrew W Taylor

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 781. doi:

Increased Sodium Iodate-Induced Retinal Degeneration in the Presence of Systemic Inflammation Caused by Collagen-Induced Arthritis Open Access

Gloriane Schnabolk; Elisabeth Obert; Nirmal Banda; Baerbel Rohrer

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 782. doi:

The upregulation of GPR3 during experimental autoimmune uveitis (EAU) and inhibition of pathogenic uveitogenic T cells by GPR3 ligand cannabidiol (CBD) Open Access

Zhao-Hui Song; Jingrui Wang; Alyssa S Laun; Deming Sun; Henry J Kaplan; Hui Shao

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 783. doi:

Upregulation of CX3CR1 on CD4+ T cells during Experimental Autoimmune Uveoretinitis Open Access

Amy Ward; Oliver Hugh Bell; Louis Scott; David Copland; Andrew D Dick; Lindsay B Nicholson

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 784. doi:

A role of Th1/17 cells migrating across the blood-retinal-barrier in experimental autoimmune uveitis Open Access

Yi hsing Chen; Malihe Eskandarpour; Mahid Chaudhry; Xiaozhe Zhang; Susan Lightman; Virginia L Calder

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 785. doi:

Parabiosis Shows That Interplay of Donor Effector and Regulatory T cells Influences the Outcome of Disease Induction in the Partner Mouse. Open Access

Scott W McPherson; Neal D Heuss; Md Abedin; Mark Pierson; Dale S Gregerson

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 786. doi:

Fecal microbiota transplantation from Behcet’s disease patients exacerbates experimental autoimmune uveitis activity Open Access

Qingfeng Wang; Shenglan Yi; Ziyu Du; Peizeng Yang

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 787. doi:

Metagenome sequencing identifies unique microbiome associated with post fever retinitis in the vitreous body Open Access

Arunasri K.; Mahesh Malleshwarapu; Sai Prashanthi Gumpili; Mudit Tyagi; Rajeev Kumar Pappuru; Savitri Sharma; Shivaji Sisinthy

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 788. doi:

Effects of growth hormone-releasing hormone receptor antagonist in experimental autoimmune intraocular inflammation Open Access

WAI KIT CHU; Jian Li; Jing Na He; Wong Ying Yip; Liutao Guo; Oi Man Mandy Wong; Calvin C P Pang

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 789. doi:

Topical application of Cyclosporine-A-MiDROPS™ for treatment of Autoimmune Uveitis Open Access

Terry G Coursey; Phillip A Vanlandingham; Ashley K. Sparkes; Drew Wassel; Alexander B Quiambao; Didier J Nuno; Rafal Farjo

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 790. doi:

A specific IKKβ inhibitor suppresses experimental autoimmune uveoretinitis in mice Open Access

Ye Liu; Nobuyoshi Kitaichi; Di Wu; Keitaro Hase; Daiju Iwata; Kenichi Namba; Atsuhiro Kanda; Kousuke Noda; Susumu Ishida

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 791. doi:

Laquinimod effectively inhibits development of EAU and its associated immune effector responses Open Access

Biying Xu; Xiuzhi Jia; Jihong Tang; Rachel R Caspi; Igal Gery

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 792. doi:

Tofacitinibhas preventive and therapeutic effects for uveitis in mice model Open Access

YICHEN XIAO; Wenru Su

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 793. doi:

Targeting PEDF for the treatment of experimental autoimmune uveitis Open Access

Xiaomin Zhang; Zhihui Zhang; Shuang Chen; Nu Chen; Jian-Xing (Jay) Ma; Xiaorong Li

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 794. doi:

Induced pluripotent stem cells-derived suppressor cells ameliorate experimental autoimmune uveoretinitis in mice Open Access

Keitaro Hase; Kenichi Namba; Nobuyoshi Kitaichi; Daiju Iwata; Hyuma Tsuji; Haruka Wada; Ken-ichiro Seino; Susumu Ishida

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 795. doi:

Targeting the leukotriene B4 pathway and/or complement C5 via dual-functional recombinant rVA576 (Coversin) in Experimental Autoimmune Uveitis (EAU) Open Access

Mali Eskandarpour; Xiaozhe Zhang; Grazyna Galatowics; Miles Nunn; Wynne Weston-Davies; Virginia L Calder

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 797. doi:

Vitreal cytokine profile in rats innoculated with bovine insoluble Melanin Associated Antigen, type 1 collagen, and type 2 collagen, and the influence of age and sex on uveitis Open Access

Stephanie Osinchuk; Tracy Wilson-Gerwing; Alan Rosenberg; Bruce Grahn

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 798. doi:

The protective effect of low dose of lipopolysaccharide pretreatment on EIU rats was related to down-regulation of CSF-1 and up-regulation of LRR-1. Open Access

Hong Lu; Yunli Ling

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 799. doi:

Chronic model of uveitis in rabbit - Efficacy of Triamcinolone Acetonide Open Access

Yann Quentric; Sophie Antonelli; Virginie Mauro; Nicolas Cimbolini; Laurence Feraille; Elena Pierre-Paul

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 800. doi:

Characterization of a Chronic Panuveitis Model in the Rabbit. Open Access

David Culp; Justin Prater; Adam Moser; Brian C Gilger

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 801. doi:

Monkey acute uveitis induced by a TLR2 agonist Open Access

Ke Mu; Yuliang Feng; Chaomao Zhang; Peng Liao; Huangjian Hou; Jianjun Zhao; Feng Wang; Yujiao Wang; Hui Zhang

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 802. doi:

P-glycoprotein expression in patients with non-infectious uveitis on non-steroidal immunosuppressive therapy Open Access

Soumyava Basu; Ravichandra Tagirasa; Khokan Rana

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 803. doi:

MicroRNAs as biomarkers for ocular involvement in juvenile idiopathic arthritis Open Access

Michal Kramer; Shani Pillar; Nir Pillar; Gil Amarilyo; Liora Harel; Noam Shomron

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 804. doi:

Single cell molecular analysis of remnant vitreous from cytology-proven vitreoretinal lymphoma allows additional genetic information for diagnosis and prognostication. Open Access

Anita SY Chan; Wei Jian Tan; Mona Meng Wang; Soon Phaik Chee; Paola Castagnoli; TongSeng Lim

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 805. doi:

Phenotype of innate immune cells in uveitis associated with axial spondyloarthritis- versus juvenile idiopathic arthritis- associated uveitis Open Access

Maren Kasper; Karoline Walscheid; Björn Laffer; Dirk Bauer; Martin Busch; Karin Loser; Thomas Vogl; Thomas Langmann; Gerd Ganser; Thomas Rath; Arnd Heiligenhaus

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 808. doi:

Analysis of peripheral inflammatory T-cell subsets and their effector functions in patients with Birdshot Retinochoroiditis Open Access

Dominika Pohlmann; Janine Trombke; Lucie Loyal; Julian Braun; Uwe Pleyer; Andreas Thiel

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 809. doi:

Serum Biomarker Levels and Their Correlation with Disease Activity in Patients with Uveitis Open Access

MEHMET YAKIN; Benjamin Chaigne-Delalande; Jung Wha Lee; H Nida Sen

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 810. doi:

FLOW CYTOMETRY IN INTRAOCULAR SAMPLES OF HUMAN UVEITIS. IS THERE A CELLULAR SIGNATURE? Open Access

Ester Carreno; Cristina Serrano; Nélida Muñoz; Olga Sánchez-Pernaute; Nicolás Alejandre

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 811. doi:

Comparison of cytokine concentrations in vitreous fluids among uveitis diseases

Open Access

Toshikatsu Kaburaki; Hisako Ono; Rie Tanaka; Tomohito Sato; Masaru Takeuchi; Hideto Tozawa; Mari Katsura; Wada Youichiro; Shintaro Shirahama; Hirotsugu Soga; Hidetoshi Kawashima; Makoto Aihara

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 812. doi:

Single immune-cell based diagnosis of ocular liquid biopsies with small volume and sample size using DEPArray technology Open Access

TongSeng Lim; Wei Jian Tan; Mona Meng Wang; Paola Ricciardi-Castagnoli; Anita SY Chan

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 813. doi:

Validation Study of ISOLD score in classifying Primary Vitreoretinal Lymphoma vs. Uveitis Open Access

David Kuo; Maggie Wei; H Nida Sen

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 814. doi:

Autoimmune retinopathy in two patients with stiff-person syndrome with anti-GAD65 autoantibodies Open Access

Mauricio E Vargas; Huber Vasconcelos Junior; Sufang Yang; Grazyna Adamus; Paul Yang

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 815. doi:

Detection of autoantibodies against TRPM1 in cutaneous metastatic melanoma Open Access

Robert Duvoisin; Gaoying Ren; Tammie L Haley; Matthew Taylor; Catherine W Morgans

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 816. doi:

How the genetic evolution happened in Bechet’s diseases along the Silk Route: China, Turkery and United Kingdom? Open Access

Yuan Tian; Ana Poveda Gallego; Mothith Shamdas; Hedayat Javidi; Saaeha Rauz; Philip Ian Murray; Peizeng Yang; Graham R Wallace

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 817. doi:

Positivity of rubella virus in steroid-resistant intermediate uveitis of unknown etiology Open Access

Hiroshi Takase; Mitsunao Ide; Kyoko Ohno-Matsui

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 818. doi:

Outcomes of diagnostic anterior chamber tap in uveitis patients Open Access

Safa Arfeen; Pooja Bhat; Ann-Marie Lobo

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 819. doi:

The effect of PCR testing on the clinical course in herpetic uveitis Open Access

Eri Matsumoto; Kazuichi Maruyama; Yoshinori Oie; Takeshi Soma; Noriyasu Hashida; Motokazu Tsujikawa; Kohji Nishida

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 820. doi:

High-dimensional immune cell profiling characterizes features of peripheral NK cell repertoires in CMV anterior uveitis Open Access

Nobuyo Yawata; Jay Siak; Kaing Woon; Xinru Lim; Soon Phaik Chee; Makoto Yawata; Yoichi Kawano; Koh-hei Sonoda

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 821. doi:

Human Leukocyte Antigen B*51:01 and C*14:02 Indicates Susceptibility towards Recurrent Cytomegalovirus Anterior Uveitis Open Access

Owen Png; Nobuyo Yawata; Xinru Lim; Kaing Woon; Anne Jansen; Samanthila Waduthantri; Soon Phaik Chee; Jay Siak

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 822. doi:

Polymerase Chain Reaction for the Diagnosis of Chorioretinal Infections: Comparative Study of Testing in a Single Institution Open Access

Janet L Davis; Sulaiman Alhumaid

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 823. doi:

Polymerase Chain Reaction in the Diagnosis of Toxoplasma gondii Chorioretinitis Open Access

JOHN W HINKLE; Sulaiman Alhumaid; Darlene Miller; Janet L Davis; Thomas A Albini

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 824. doi:

Nanopore Sequencing for Rapid Diagnosis of Microbial Keratitis Open Access

Liying Low; Radhika Pooja Patel; Ghazala Begum; Pablo Fuentes-Utrilla; Graham R Wallace; Philip Ian Murray; Saaeha Rauz

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 825. doi:

T2 magnetic resonance assay and detection of ocular candidiasis Open Access

SHRAVANI MIKKILINENI; Rahul Komati; Nirali Shah; Hua Gao

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 826. doi:

Mycobacterium tuberculosis (M.tb) antibody and antigen biomarkers for rapid diagnosis of intra-ocular tuberculosis Open Access

Kamaljit Kaur; Michelle B Ryndak; Aniruddha Agarwal; Indu Verma; Vishali Gupta; Suman Laal

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 827. doi:

Phenotypic microarray analysis of Moraxella keratitis isolates Open Access

Cholappadi V Sundar-Raj; Nicholas A Stella; Regis P Kowalski; Robert M Q Shanks

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 828. doi:

High Throughput Sequencing reveals predominantly fungal pathogens in the vitreous of patients with presumed infectious, culture negative endophthalmitis in Southern India with implication... Open Access

Joveeta Joseph Ruben; Rajagopalaboopathi Jayasudha; Jaishree Gandhi; Savitri Sharma; Vivek Pravin Dave

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 829. doi:

Interest of QuantiFERON®-TB Gold Plus as a diagnostic test in patients with ocular inflammation (OI) Open Access

amelie Amara; Amelie Guihot; Salim Trad; Christine Fardeau; Phuc Lehoang; Valerie Touitou; Bahram Bodaghi

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 830. doi:

Fluorescence Imaging of Biofilm on Eyelashes Open Access

Michael Bahren Choi; Donna B Stolz; Eric D Donnenfeld; Henry D Perry

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 831. doi:

Clinical Utility of beta-D-glucan Testing for Detecting Fungal Chorioretinitis and/or Endophthalmitis Open Access

Michael Ammar; Robert Carroll; Anton M Kolomeyer; Gui-Shuang Ying; Gideon Whitehead; Alexander J Brucker; Benjamin J Kim

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 832. doi:

Non-liquefaciens and osloensis are the Predominant Moraxella species of Ocular Infections as Determined by DNA sequencing, MALDI-TOF MS, and Biolog ID System. Open Access

Regis P Kowalski; Samantha LaCroce; Mollie Wilson; John Romanowski; Jeff Newman; Robert M Q Shanks; Vishal Jhanji

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 833. doi:

Application of Metagenomic Deep Sequencing (MDS) to Identify an Infectious Etiology for Iridocorneal Endothelial (ICE) Syndrome Open Access

Plern Sutra; Jennifer Rose-Nussbaumer; John Alexander Gonzales; Kaidi Wang; Armin Hinterwirth; Gerami Seitzman; Nisha Acharya; Thuy Doan

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 834. doi:

Different Concentrations of Topical Fortified Vancomycin Produce Differences in Antibacterial Efficacy in an Experimental Model of MRSA Keratitis Open Access

Eric G Romanowski; John Romanowski; Kathleen A Yates; Alex Mammen; Deepinder K Dhaliwal; Vishal Jhanji; Regis P Kowalski

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 835. doi:

In vitro susceptibility of Staphylococcus aureus and Pseudomonas aeruginosa to a novel fluoroquinolone Open Access

Alejandro Arboleda; Heather Durkee; Jorge Maestre-Mesa; Maribel Hernandez; Mariela Aguilar; Harry Flynn; Jean-Marie Parel; Darlene Miller

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 836. doi:

In Vitro Susceptibilities of Methicillin-Susceptible and Resistant Staphylococci to Traditional Agents Compared to a Novel Fluoroquinolone Open Access

James Lin; Kenneth Fan; Nathan Pirakitikulr; Darlene Miller; Harry Flynn

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 837. doi:

Changes in Staphylococcus aureus Virulence Factors and Host Immune Response Following Rose Bengal Photodynamic Antimicrobial Therapy Open Access

Heather Durkee; Alejandro Arboleda; Jorge Maestre-Mesa; Mariela Aguilar; Guillermo Amescua; Jean-Marie Parel; Darlene Miller

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 838. doi:

Inference of netilmicin resistance rate for Staphylococci ocular isolates in France Open Access

Andrea Sudano Roccaro; Claude-James Soussy; Francesco Giuliano; Maria Grazia Mazzone

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 839. doi:

Rock-Scissor-Paper-Rules of Engagement in Interspecies Interactions and Outcomes in Contact lens Associated Microbial Communities Open Access

Darlene Miller; Jorge Maestre-Mesa; Eduardo Alfonso

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 840. doi:

Medication burden for patients with bacterial keratitis Open Access

Maria A Woodward; Dena Ballouz; Josh Errickson; Nenita Maganti; Megan Tuohy

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 841. doi:

Excimer-Laser and mitomycin C 0.02% to treatment acanthamoeba keratitis Open Access

Navid Ardjomand; Loay Daas; Julia Walochnik; Klemens Kaiser; Marija Anticic; Berthold Seitz; Yosuf El-Shabrawi

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 842. doi:

Outcomes of Cytomegalovirus Retinitis–Related Retinal Detachment in Acquired Immune Deficiency Syndrome (AIDS) Patients Following Pars Plana Vitrectomy in Southern Thailand Open Access

Virintorn Prapakornkovit; Wantanee Sittivarakul; Mansing Ratanasukon; Patama Bhurayanontachai; Pichai Jirarattanasopa

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 843. doi:

Clinical-Microbiological profile and antibiotic sensitivity in microbial keratitis in elderly patients. Open Access

Eduardo Jose Polania-Baron; Enrique O Graue-Hernandez; Alejandro Navas; Arturo J Ramirez-Miranda; Victor Manuel Bautista-de Lucio

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 844. doi:

Gram-negative endophthalmitis; microbiology, clinical associations and visual outcomes in Victoria, Australia Open Access

Louis Stevenson; Rosie C.H Dawkins; Harshvardha Sheorey; Andrew Hurley; Penelope J Allen

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 846. doi:

The German keratomycosis registry - results of a multi-center study Open Access

Gerd Geerling

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 847. doi:

Microbial keratitis following corneal transplantation Open Access

Pauline Khoo; Maria Paulina Cabrera Aguas; Stephanie L Watson

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 848. doi:

Microbial keratitis resulting in evisceration and enucleation in Sydney, Australia Open Access

Maria Paulina Cabrera Aguas; Pauline Khoo; Stephanie L Watson

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 849. doi:

Colistin resistance in gram negative ocular infections: prevalence, clinical outcome and antibiotic susceptibility patterns Open Access

Sanchita Mitra; Soumyava Basu; Suryasnata Rath; Srikant K Sahu

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 850. doi:

Clinical presentations, microbiology, management outcomes of endogenous endophthalmitis and a comparison with similar cohorts worldwide Open Access

Avinash Pathengay; Vivek Dave; Taraprasad Das; Bhavik Panchal; Savitri Sharma; Rajeev Reddy Pappuru

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 851. doi:

Lesions of the Vitreous, Choroid, and Retina in Injection Drug Users (IDUs) Hospitalized with Bloodstream Infections Open Access

Kathy Tsamis; Jessica Weinstein; Erin Barnes; James Peacock; Margaret Greven

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 852. doi:

Longitudinal Trends in Antibiotic Resistance Among Staphylococci Collected in the ARMOR Study Open Access

Penny A Asbell; Christine M Sanfilippo; Heleen H DeCory

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 853. doi:

Asia Cornea Society Infectious Keratitis Study: Pseudomonas aeruginosa infectious keratitis Open Access

Roger W Beuerman; A. Mishra; AL Tan; MH Periayah; X Lian; R Sultana; SE Saffari; WB Khor; Jodhbir Mehta; Donald Tan

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 854. doi:

Trends in pathogens and antibiotic resistance of corneal culture isolates in infectious keratitis in Sao Paulo, Brazil, over a 5-year period Open Access

Luiza Manhezi Shin de Shin de Oliveira; Tatiana Tanaka; Juliana Mika Kato; Flávia Rossi; João Nóbrega de Almeida Junior; Thais Romano Sabato di Gioia; Verônica Bresciani Giglio; Milton Ruiz Alves; Ruth Miyuki Santo

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 855. doi:

The Resurgence of Ocular Syphilis in British Columbia: 2013-2016 A Retrospective Chart Review Open Access

Maryam Eslami; Gelareh Noureddin; Simon Warner; Troy Grennan

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 856. doi:

Ocular syphilis: clinical manifestations and visual outcomes Open Access

Merav Koschitzky; Kunyong Xu; Szilard Kiss

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 857. doi:

Candida keratitis: epidemiology, management, and clinical outcomes Open Access

Grace Lei Qiao; Jennifer Ling; Titus Wong; Sonia Yeung; Alfonso Iovieno

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 858. doi:

Singapore Ocular Tuberculosis Immunity Study (SPOTIS) Open Access

Ae Ra Kee; Paul Edward Hutchinson; John Edward Connolly; Nobuyo Yawata; Jay Siak; Rupesh Vijay Agrawal

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 859. doi:

Collaborative Ocular Tuberculosis Study (COTS) Consensus guidelines on initiating antitubercular therapy in presumed tubercular choroiditis Open Access

Vishali Gupta; Rupesh Vijay Agrawal; Ilaria Testi; Sarakshi Mahajan; Dhananjay Raje; Aniruddha Agarwal; Dinesh Gunasekeran; John H Kempen; Quan Dong Nguyen; Carlos Pavesio

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 860. doi:

Collaborative Ocular Tuberculosis Study (COTS) consensus guidelines on initiating antitubercular therapy in presumed tubercular retinal vasculitis Open Access

Rupesh Vijay Agrawal; Ilaria Testi; Sarakshi Mahajan; Dhananjay Raje; Aniruddha Agarwal; Dinesh Gunasekeran; John H Kempen; Quan Dong Nguyen; Carlos Pavesio; Vishali Gupta

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 861. doi:

Collaborative Ocular Tuberculosis Study (COTS) Consensus guidelines on initiating antitubercular therapy in intermediate uveitis and panuveitis Open Access

Ilaria Testi; Rupesh Vijay Agrawal; Sarakshi Mahajan; Dhananjay Raje; Aniruddha Agarwal; Dinesh Gunasekeran; John H Kempen; Quan Dong Nguyen; Carlos Pavesio; Vishali Gupta

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 862. doi:

Microbial Keratitis After Penetrating and Endothelial Keratoplasty Open Access

Nicolas Dohse; Turner D Wibbelsman; Sara Rapuano; Kristin Hammersmith; Parveen Nagra; Christopher J Rapuano; Zeba A Syed

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 863. doi:

Fumagillin in microsporidial keratitis Open Access

Faisal Aljassar; Samir Shoughy; Khalid Tabbara

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 864. doi:

Understanding fungal keratitis pathogenesis through a reverse-translational approach. Open Access

Kevin K Fuller; Marina Evette Brown; David Giacalone; Jay Dunlap; Tom Lietman; Robert Cramer; K Dharmalingam; Michael Zegans

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 865. doi:

Efficacy of voriconazole on Acanthamoeba Keratitis: Prospective Randomized Double masked trial Open Access

Bhupesh Bagga; Savitri Sharma; Ruchi gour; Joveeta Joseph Ruben; Ashik Mohamed

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 868. doi:

Comparison Study on Aspergillus Pathogenicity of Corneal Clinical Isolates And Standard Strain: The Relationship Between Invasiveness And Growth Characteristics Open Access

Yingyu Li; Pei Zhang; Ziyuan Liu; Wei Wang

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 869. doi:

Role of Circumferential Full Thickness Scleral Debridement in Fulminant Infective Ring Scleritis Open Access

Samendra Karkhur; Alok Sen; Pratik Shenoy; Muhammad Hassan; Muhammad Sohail Halim; Murat Hasanreisoglu; Rubbia Afridi; Yasir Jamal Sepah; Diana V Do; Quan Dong Nguyen; Vishali Gupta

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 870. doi:

Limbal Stem Cell Deficiency Associated with Herpetic Keratitis: A Retrospective Study Open Access

Jimena Tatiana Carreno-Galeano; Thomas Dohlman; Jia Yin; Reza Dana

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 871. doi:

Undiagnosed Ocular Syphilis Treated with Biologic Immunosuppressive Therapy Open Access

Andrew Pittner; Pauline Merrill; Palak Patel

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 872. doi:

Ocular Manifestations of Disseminated Mycobacterium Chimaera Infection After Cardiothoracic Surgery Open Access

Jingyi Ma; Nathan Carrell; Chad Baker

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 873. doi:

Cryptococcal choroiditis in the absence of cryptococcal meningitis: a novel clinical description. Open Access

Doran Spencer; Adeleh Yarmohammadi; Christopher Brian Toomey; Tyler Ofstad; William R Freeman

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 874. doi:

Electroretinography and Visual Function among Individuals Infected with Human Immunodeficiency Virus Open Access

Davin Carlton Ashraf; Leticia Dourado Alves; Alla Kukuyev Goldberg; Gary N Holland; Fei Yu; Steven Nusinowitz

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 875. doi:

Decreased optic nerve head blood flow in acute retinal necrosis Open Access

Hiroshi Keino; Makiko Nakayama; Takayo Watanabe; Yoshimasa Ando; Takashi Koto; Kazunari Hirota; Makoto Inoue; Annabelle Okada

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 876. doi:

Treatment of Cytomegalovirus Retinitis in Human Immunodeficiency Virus Seropositive Patients: Systematic Review Open Access

Chanusnun Narongchai; Somsanguan Ausayakhun

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 877. doi:

Ocular toxoplasmosis : assessment of active and scarred areas of retinochoroiditis Open Access

Pierre Duraffour; Chadi Mehanna; Florence Hoogewoud; Arnaud Touboul; Dominique Monnet; Antoine Brézin

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 878. doi:

Uncommon Presentations of Ocular Toxoplasmosis Open Access

Phillip Qu; Hussein Wafapoor

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 879. doi:

Autoreactivity against HSP70 and recoverin in patients with congenital and acquired ocular toxoplasmosis Open Access

Monica Goldberg; Antonio Ibarra; Dolores Correa

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 880. doi:

Concomitant herpetic keratitis and acute retinal necrosis Open Access

Wendy Ming; Nikhil Dewan; Sonia Yeung; Alfonso Iovieno

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 881. doi:

Prevention of Blindness from CMV Retinitis-Related Retinal Detachment by Prophylactic Argon Laser Demarcation Open Access

Lynn M Hassman; Khin Thida Oo; Marissa Larochelle; Partho Kalyani; NiNi Tun; Zaw Minn Din; Gary N Holland; David Heiden; Albert T Vitale

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 882. doi:

Higher Frequencies of Macrophages and IL-12 Expression in the Cornea of Very Young Graft Recipients Open Access

Takeshi Nakao; Yihe Chen; Jia Yin; Afsaneh Amouzegar; Reza Dana

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 883. doi:

The purinergic receptor antagonist oxidized adenosine triphosphate promotes corneal allograft survival without expanding regulatory T cells Open Access

William Foulsham; Sharad Mittal; Takeshi Nakao; Giulia Coco; Yukako Taketani; Sunil Chauhan; Reza Dana

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 884. doi:

Rho-Kinase Inhibitor Ripasudil suppresses neovascularization and inflammation in murine corneal transplanatation Open Access

Takenori Inomata; Keiichi Fujimoto; Yuichi Okumura; Mikiko Okano; Toshinari Funaki; Akira Murakami

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 885. doi:

Comparison of the therapeutic effects between topical 8-oxo-2'-deoxyguanosine and steroid in ocular chemical burn experimental model Open Access

Dong Hyun Kim; Sang-Taek Im; Sang Beom Han; Myung-Hee Chung

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 886. doi:

CSFR-1⁺ CX3CR1⁺ resident corneal macrophages regulate inflammatory corneal hemangiogenesis Open Access

Deniz Hos; Anne Kiesewetter; Claus Cursiefen; Sabine A. Eming

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 887. doi:

Development of a novel corneal epithelial dendritic cell morphology grading scale Open Access

Zahra Tajbakhsh; Cecilia Chao; Rabia Mobeen; Blanka Golebiowski; Isabelle Jalbert; Fiona Stapleton

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 888. doi:

Peripheral neutrophil phenotype and function in Ocular Mucous Membrane Pemphigoid. Open Access

Mariam Murad; Liying Low; Mohith Shamdas; Natraj Poonit; Philip Ian Murray; Saaeha Rauz; Graham R Wallace

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 889. doi:

Immuno-modulative effects of corneal endothelium on innate immune-cells as determined by transcriptome analysis. Open Access

Thabo Lapp; Daniel Boehringer; Antonia Hildebrand; Paola Kammrath Betancor; Jiaqi Fan; Thomas Reinhard; Gunther R Schlunck

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 890. doi:

Integrin αvβ8 Promotes Tolerogenic Function of CD103⁺Dendritic Cells in Corneal Transplantation Open Access

Tomas Blanco; Serra Atilla; Reza Dana

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 891. doi:

Corneal epithelial dendritic cell density in a healthy population and its relationship with age and sex: A Meta-Analysis of in vivo confocal microscope data Open Access

Rabia Mobeen; Cecilia Chao; Fiona Stapleton; Michele C Madigan; Blanka Golebiowski

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 892. doi:

Retinal inflammation after penetrating corneal surgery: the role of TNF-α and IL-1β inhibition. Open Access

XIAONIAO CHEN; Fengyang Lei; Chengxin Zhou; Eleftherios I Paschalis; James Chodosh; Claes H Dohlman; Liqiang Wang

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 893. doi:

NLRP3 inflammasome regulates acute corneal allograft rejection through enhanced phosphorylation of STAT3 Open Access

Chao Wei; Demeng Xiang; Li Ma; Hua Gao; Weiyun Shi

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 894. doi:

Local VEGF-A blockade modulates the microenvironment of corneal transplantion side Open Access

Felix Bock; Ann-Charlott Schneider; Claus Cursiefen; Manuel Koch; Raphael Reuten; Esther Mahabir; Gabriele Braun; Malte Heykants

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 895. doi:

Regulatory T cells Derived from Hosts at High Risk of Corneal Graft Rejection Have Impaired Protective Effect on Corneal Endothelial Cells Open Access

Giulia Coco; William Foulsham; Takeshi Nakao; Jia Yin; Afsaneh Amouzegar; Yukako Taketani; Sunil Chauhan; Reza Dana

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 896. doi:

Local Adoptive Transfer of Plasmacytoid Dendritic Cells as a Novel Therapeutic Approach for Corneal Neovascularization Open Access

Arsia Jamali; Maria J Lopez; Deshea L Harris; Victor German Sendra; Nicholas Pondelis; Gustavo Ortiz; Pedram Hamrah

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 897. doi:

Migration rate of presumed immature dendritic cells in the healthy living human cornea as imaged with In vivo corneal confocal microscopy Open Access

Luisa H. Colorado; Katie Edwards; Holly Rose Chinnery; Haydee E P Bazan

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 898. doi:

Corneal collagen cross-linking pretreatment mitigates inflammation, hemangiogenesis and lymphangiogenesis in rats Open Access

Wei Chen; Yirui Zhu; Peter Reinach; Jia Qu

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 899. doi:

Corneal Plasmacytoid Dendritic Cell Depletion Results in Increased Expression of Neurodegenerative Markers in the Trigeminal Ganglion Open Access

Brendan Kenyon; Arsia Jamali; Yashar Seyed-Razavi; Gustavo Ortiz; Deshea L Harris; Pedram Hamrah

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 900. doi:

Post injury mu-opioid receptor (mOR) expression in the oculo-trigeminal axis: Is Less mOR? Open Access

Nicholas Fowler; Romulo Albuquerque; Jooyoung Cho

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 901. doi:

β2 adrenoceptor inhibition reduces the severity of Pseudomonas aeruginosa keratitis in mice Open Access

Qingjun Zhou; lixin Xie; Xiubin Ma

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 902. doi:

Influence of punctate superficial keratitis on intraocular pressure measured with Goldmann applanation tonometer and noncontact tonometer Open Access

Daisuke Shimizu; Shuichi Yamamoto

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 904. doi:

Effect of high glucose on corneal epithelial cellular and barrier functions Open Access

Ashley Marie-Arambula Barbarino; Saleh Alfuraih; Kiumars Shamloo; Ajay Sharma

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 905. doi:

Engineering an electrospun nanofiber to direct corneal epithelial cell proliferation and morphology Open Access

Chau Vo; Hyun Jong Lee; Gabriella Fernandes-Cunha; David Myung

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 906. doi:

Insulin mediates mitochondrial stability in corneal epithelial cells Open Access

Danielle M Robertson; Rossella Titone; Whitney Stuard; Meifang Zhu

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 907. doi:

Jagged1-mediated Notch Signaling Activation Regulates the Differentiation and Stratification of Human Limbal Stem/Progenitor Cells in vitro Open Access

Sheyla Gonzalez; Maximilian Halabi; Sophie Xiaohui Deng

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 908. doi:

The effect of near-infrared photobiomodulation on in vitro cornea wound healing. Open Access

Maud Gorbet; Parisa Hamilton; Saman Mohammadi; Daniel Choi; Alexa Roeper

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 909. doi:

Transient mitomycin C treatment of human corneal limbal epithelial cells induces secretion of cytokines. Open Access

Mary Ann Stepp; Sonali Pal-Ghosh; Gauri Tadvalkar; Audrey E K Hutcheon; James D. Zieske; Xiaoqing Q Guo

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 910. doi:

Roles of vasoactive intestinal polypeptide expression in diabetic and nerve degenerated mice corneal epithelial regeneration Open Access

Yangyang Zhang; FU-SHIN YU

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 911. doi:

TNFα induces corneal epithelial proteolytic activity in response to ER stress Open Access

Ashley Woodward; Antonio Di zazzo; Stefano Bonini; Pablo Argueso

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 912. doi:

Proteomics profiling to elucidate miR-146a targets in primary limbal epithelial cells Open Access

Mehrnoosh Saghizadeh; Adam Poe; Mangesh Kulkarni; Andrei A Kramerov; Alexander V Ljubimov; Yasaman Jami-Alahmadi; James Wohlschlegel

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 913. doi:

The impact of zinc oxide and vanadium pentoxide nanoparticles on corneal epithelial wound healing in vitro and in vivo Open Access

Atsuhiko Fukuto; Soohyun Kim; Brooke L. Gates; Laura Van Winkle; Kent E. Pinkerton; Sara M Thomasy

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 914. doi:

Secreted Ly-6/uPAR Related Protein-1 (SLURP1) modulates inflammation by moderating epithelial cells response to inflammatory agents Open Access

Sudha Swamynathan; Gregory Campbell; Anil Tiwari; John Sebastian Gnalian; Shivalingappa K Swamynathan

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 915. doi:

Corneal mechanotransduction drives TRPV4-dependent release of the transmitter ATP Open Access

Luka Lapajne; Monika Lakk; Lara Gubeljak; Oleg Yarishkin; Marko Hawlina; David Krizaj

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 916. doi:

Comparison of different methods to isolate mouse limbal epithelial cells for single-cell analysis Open Access

Zhenwei Song; Hua Mei

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 917. doi:

Corneal epithelial thickness and Bowman’s layer thickness-mapping in patients with unilateral keratoconus using large Field of View Polarization-Sensitive Optical Coherence Tomography. Open Access

Niklas Pircher; Florian Beer; Stephan Holzer; Michael Pircher; Christoph K Hitzenberger; Gerald Schmidinger; Jan Lammer

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 918. doi:

UV light-blocking contact lenses prevent UVB-induced DNA and oxidative damage of the limbal stem cell niche, protect against inflammation and maintain putative stem cell phenotype Open Access

Maria Notara; Sara Behoudifard; Bjoern Schumacher; Claus Cursiefen

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 920. doi:

Barrier strengthening in corneal epithelium by nucleic acid stimulation is a reaction via toll-like receptor 3 Open Access

Yuriko Ban; Yulia Aziza; Chie Sotozono; Shigeru Kinoshita

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 921. doi:

The characterization of adipose-derived stem cell spheroids as well as their conditioned medium effect on co-culture of dorsal root ganglion and corneal epithelial cells Open Access

Shiwei Liu; Chan Wang; Quan Yu; Jun Zhang; Jiansu Chen

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 922. doi:

Sirtuin1 deficiency suppresses migration during corneal epithelial wound healing Open Access

yong lin; Li Li; Qi Liu; Dongsheng Yan

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 923. doi:

Pediatric Ocular Surface Disease Associated with Suspected Abuse Open Access

Christine Shieh; Mehak Aziz; Minas T Coroneo; Gerald W Zaidman; Louise A Mawn

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 924. doi:

The role of insulin-like growth factor binding protein 3 (IGFBP-3) in mitochondrial homeostasis in human corneal epithelial cells Open Access

Whitney Stuard; Rossella Titone; Danielle M Robertson

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 925. doi:

Corneal neurotization protects the cornea from epithelial thinning in a rat model of neurotrophic keratopathy Open Access

Kira Antonyshyn; Joseph Catapano; Tessa Gordon; Gregory H Borschel

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 926. doi:

Effect of trypsin-EDTA on expression of DNA damage repair enzyme APE1 in human limbal epithelial cells. Open Access

Yolanda Lorenzo Corrales; Bjørn Otto Nicolaissen; Giang Nguyen; Kahsai Beraki; Morten C. Moe; Goran Petrovski; Bjørn Nicolaissen

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 927. doi:

Optimal magnitude of shear stress for human corneal epithelial cell proliferation in microfluidic culture system Open Access

SeongKwang Cha; Jae-hyung Kim; Yongsook Goo

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 928. doi:

The cytotoxic effect of Titanium oxide nanoparticles on cultured human corneal epithelial cells Open Access

Choul Yong Park

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 929. doi:

Histatin 5 can reduce apoptosis induced by hyperosmolar conditions in human corneal epithelial cells. Open Access

Vinay Kumar Aakalu; Dhara Shah; Sushma Kalmodia; Marwan Ali; Arun Balasubramaniam; Kyung-No Son

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 930. doi:

Impact of Contact Lens Wear on Epithelial Alterations in Keratoconus Open Access

Luigina Sorbara; Maud Gorbet; Kostadinka K Bizheva; Jose Lamarca Mateu; Jose Carlos Pastor; Miguel J Moldonado; Denise Hileeto

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 932. doi:

Differential DNA methylation between diabetic and non-diabetic human corneolimbal cells and limbal-derived iPSCs Open Access

Ruchi Shah; Tanya M Spektor; Vasu Punj; Sue Turjman; Sean Ghiam; Jiho Kim; Mehrnoosh Saghizadeh; Andrei A Kramerov; Alexander V Ljubimov

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 934. doi:

Preoperative Reduction of Corneal Neovascularization by Fine-Needle Vessel Coagulation Combined with Bevacizumab Decreases the Risk of Graft Rejection after Subsequent High-Risk Keratopla... Open Access

Claus Cursiefen; Bjoern Bachmann; Deniz Hos

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 935. doi:

The influence of mesenchymal stem cells on traumatic corneal neovascularization on an animal model. Open Access

Demetrios Evagelos Pirounides; KOSTAS BOBORIDIS; ANASTASIA KOMNENOU; NIKOLAOS PAPAIOANNOU; ELENI GOUNARI; ALEXANDROS ALEXANDRIDIS; EVANGELIA KOFIDOU; GEORGIOS KOLIAKOS; VASILEIOS KARAMPATAKIS

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 936. doi:

Establishing a Correlation Between Cornea Neovascularization and Cornea Opacity in a Suture Induce CNV Model in Rabbit Open Access

Christian Hissom; Nicholas Cook; Kayla Martinaz; Jenny Walters; Andrew Zhao; John Quach; Dinh Albright; Jeff Parson; Matt Lyulkin; Scott Womble; Glenwood G Gum; Vatsala Naageshwaran; Sandeep Kumar

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 937. doi:

Removal of suture-induced corneal neovascularization in rabbits using concurrently applied nanosecond laser pulses and ultrasound Open Access

Yixin Yu; Xinyi Xie; Yu Qin; Xiaobo Xia; Maria A Woodward; Xinmai Yang; Xueding Wang; Yannis Mantas Paulus

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 938. doi:

IL-21 pre-stimulated MSC derived exosomes suppressing corneal neovascularization Open Access

Ziqi Yang; Yan Liu; Tian Zhou; Xiaowei Zhu; Chang He; Xialin Liu

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 940. doi:

Comparison of UV-light crosslinking and Fine needle-diathermy to regress pathological corneal lymphatic and blood vessels in vivo Open Access

Yanhong Hou; Viet Nhat Hung Le; Felix Bock; Claus Cursiefen

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 941. doi:

Tyrosinase is a novel endogenous inhibitor of lymphangiogenesis Open Access

Thomas Clahsen; Christian Büttner; Birgit Regenfuss; Tim Gabriel; Felix Bock; André Reis; Claus Cursiefen

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 942. doi:

Therapeutic Effect of Topical Apatinib in a Murine Model of Corneal Neovascularization Open Access

HYEON JEONG YOON; Ying Li; Lan Li; Ru Jun Jin; Je Moon Woo; Kyung Chul Yoon

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 943. doi:

Proteomics-based characterization of the influence of MMP14 on the protein content of corneal fibroblast-derived exosomes Open Access

Kyuyeon Han; Jin-Hong Chang; Dimitri T Azar

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 945. doi:

Inhibitory effect of Conbercept on corneal neovascularization in rabbits with alkali burn Open Access

Na Xu; Xinyi Wu

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 946. doi:

Repair Effect of Morphogenetic Protein 4 on Rat Corneal Epithelial Injury Open Access

Yan Zhang; Shurong Wang; Yuxi He

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 947. doi:

Signals from sphingosine-1-phosphate receptor type 3 involvement in vascular formation by endothelium and in VEGF expression in macrophages in vitro. Open Access

Shingo Yasuda; Takayoshi Sumioka; Yuka Okada; Masayasu Miyajima; Kana Ichikawa; Shizuya Saika

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 948. doi:

Impaired angiogenic response in cornea by lacking TRPV4 in mice Open Access

Takayoshi Sumioka; Yuka Okada; HIroki Iwanishi; Shingo Yasuda; Masayasu Miyajima; Shizuya Saika

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 949. doi:

Role of Substance P in Promoting Corneal Neovascularization Open Access

Lingjia Liu; Takeshi Nakao; Reza Dana; Jia Yin

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 950. doi:

Plasmacytoid Dendritic Cells Inhibit Vascular Endothelial Cell Proliferation and Differentiation through the Angiostatic Molecule Platelet Factor-4 Open Access

Deshea L Harris; Arsia Jamali; Abdo Abou-Slaybi; Pedram Hamrah

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 951. doi:

En-face morphometric analysis of the human limbal lymphatic vasculature Open Access

Bernhard Steger; Christoph Palme; Vito Romano; Sajjad Ahmad; Christof Seifarth; Bryan Williams; Yalin Zheng; Mohit Parekh; Stephen B Kaye

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 953. doi:

Keratocytes promote corneal neovascularization through MMP13 induced by PPARα-inhibition Open Access

Xue Wang; Liying Tang; Wensheng Li; Yongxiong Chen

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 954. doi:

GNAQ and GNA11 in circulating tumor DNA as a novel liquid biopsy-based biomarker for Uveal Melanoma Open Access

Prisca Bustamante; Thupten Tsering; Boli Fan; Sonia Callejo; Miguel N Burnier; Julia Burnier

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 956. doi:

Class 2 metastasizing uveal melanomas arise through BAP1 loss and epigenetic reprogramming to a migratory neural crest-like state Open Access

Matthew Field; Parker Bussies; Louie Cai; Christina Decatur; Jeffim Kuznetsov; Stefan Kurtenbach; J. William Harbour

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 957. doi:

Exploratory study of candidate genes other than BAP1 associated with hereditary predisposition to uveal melanoma Open Access

Mohamed H Abdel-Rahman; Klarke M Sample; Timothy Grosel; Ben Kelly; David Gordon; Maciej Pietrzak; Robert Pilarski; Frederick Davidorf; Peter White; Colleen M Cebulla

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 958. doi:

Subpopulations of uveal melanoma cells have distinct roles and cooperate to promote hematogenous dissemination Open Access

Stephen S Phillips; Gustav Stålhammar; Thonnie Rose See; Hans E Grossniklaus

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 959. doi:

Proteomics of Metastatic and Non-Metastatic Uveal Melanoma Open Access

John W Crabb; Jack S Crabb; Geeng-Fu Jang; Belinda Willard; Bo Hu; Helen Kalirai; Arun D Singh; Sarah E Coupland

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 960. doi:

Retinal oximetry in choroidal melanoma and nevi Open Access

Niels J Brouwer; Marina Marinkovic; Jaco C Bleeker; Einar Stefánsson; Gregorius P.M. Luyten; Martine J Jager

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 961. doi:

Use of machine learning for prediction of ocular conservation and visual outcomes after proton beam radiotherapy for choroidal melanoma Open Access

Stylianos Serghiou; Bertil E Damato; Armin R Afshar

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 962. doi:

Restoring visual function in models of inherited blindness using selective histone deacetylase 6 inhibitors Open Access

Husvinee Sundaramurthi; Andrea Cerquone Perpetuini; Ailis Moran; Triona Ní Chonghaile; Breandan N Kennedy

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 963. doi:

Vision and OCT Outcomes Following 2018 Aflibercept Recall Open Access

Nate Benner; Samantha D'Amico; Brian Y Kim; Christopher J. Brady

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 964. doi:

Temporal properties of dopamine turnover in the mouse retina: a mathematical model Open Access

Morven Cameron; Victor Perez Fernandez; John Morley; Paul Breen

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 965. doi:

Peptain-1 for neuroprotection in Glaucoma Open Access

Dorota L Stankowska; Mihyun Nam; Rooban Nahomi; Renuka Chaphalkar; Rafal Fudala; Raghu R Krishnamoorthy; Ram H Nagaraj

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 966. doi:

Measurement and analysis of the vitreous biochemical data in diabetes mellitus patients Open Access

Hiroki Mieno; Kentaro Kojima; Kazuhito Yoneda; Kenji Nagata; Tohru Inaba; Yoshinori Marunaka; Chie Sotozono

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 967. doi:

Vigabatrin-induced retinal bipolar cell plasticity in C57BL/6J mice Open Access

Kore Chan; Brad Wahlgren; Shawna Gloe; James N Ver Hoeve; Mrinalini Hoon; Bikash R Pattnaik; Jeremy Williams; Julie A Kiland; Erwin Jansen; Gajja Salomons; Dana Walters; Jean-Baptiste Roullet; K Michael Gibson; Gillian J McLellan

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 968. doi:

Fourier Waveform Amplitude Distribution Using A Novel Non-Invasive Method of Retinal Vascular Pulse Waveform Assessment Open Access

Anmar Abdul-Rahman; Bill Morgan; Martin Hazelton; Brigid Betz-Stablein; Dao-Yi Yu

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 969. doi:

Restoration of Sight in Geographic Atrophy using a Photovoltaic Subretinal Prosthesis Open Access

Daniel V Palanker; Yannick Le Mer; Ralf Hornig; Guillaume Buc; Martin Deterre; Vincent Bismuth; Jose Alain Sahel

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 970. doi:

Phase 2b Study of Brimonidine DDS: Potential Novel Treatment for Geographic Atrophy Open Access

William R Freeman; Francesco Bandello; Eric H Souied; Robyn H Guymer; Sunir Garg; Fred Kuanfu Chen; Ryan M Rich; Frank G Holz; Yan Li; Kevin Kerr; Francisco J. Lopez

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 971. doi:

Demographic Analysis of a Randomized, Double Masked, Placebo Controlled Study Evaluating ORACEA® in Geographic Atrophy Secondary to Non-Exudative Age- Related Macular Degeneration (TOGA) Open Access

Suruchi Bhardwaj Bhui; Eric Lien; Ashton Leone; James T Patrie; Paul A. Yates

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 972. doi:

Evaluation of Baseline Factors on Progression in a Large Phase-2 Clinical Trial for Geographic Atrophy (FILLY Study) Open Access

Nathan Steinle; Mohamed Hamdani

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 973. doi:

Elamipretide, a Mitochondria-Targeted Drug, for the Treatment of Vision Loss in Dry AMD with Noncentral Geographic Atrophy: Results of the Phase 1 ReCLAIM Study Open Access

Scott W Cousins; Michael John Allingham; Priyatham S Mettu

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 974. doi:

Pharmacological antagonism of mineralocorticoid receptor exerts VEGF-independent anti-angiogenic effects: Implication for wet AMD Open Access

Francine F Behar-Cohen; Irmela Mantel; Emmanuelle Gelize; Carlo Rivolta; Jérémie Ganonica; Frederic Jaisser; Min Zhao

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 975. doi:

Anti-angiogenic and anti-scarring dual action of an anti-Fibroblast Growth Factor-2 aptamer in animal models of retinal disease Open Access

Robert B Bhisitkul; Yusaku Matsuda; Yosuke Nonaka; Satoshi Futakawa; Kazumasa Akita; Toshiaki Nishihata; Masatoshi Fujiwara; Yusuf Ali; Yoshikazu Nakamura

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 976. doi:

Gut microbiota intensifies retinal vascular defects by targeting adherens junction protein p120-catenin in angiotensin converting enzyme 2 (ACE2) deficient type 1 diabetes (T1D) Open Access

Ram Prasad; Yaqian Duan; Gopalkrishna Sreejit; Jason L. Floyd; Baskaran Athmanathan; Prabhakara R Nagareddy; Maria B Grant

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 977. doi:

Dyslipidemia-associated activation of monocyte-derived macrophages in diabetic retinopathy Open Access

Guillaume Blot; lucile vignaud; Hugo Charles-messance; Wassila Carpentier; David Rivera; Aida Jimenez-Corona; Sebastien Augustin; Aude Couturier; Jose Alain Sahel; Enrique O Graue-Hernandez; Yonathan Garfias; Florian Sennlaub; Xavier Guillonneau

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 978. doi:

Protective effects of Intravitreal injection of human CD34+ stem cells from bone marrow on diabetic retinopathy in a murine model Open Access

Amirfarbod Yazdanyar; Pengfei Zhang; Christian Dolf; whitney Cary; Missy Pham; Jan Nolta; Robert J Zawadzki; Nicholas Marsh-Armstrong; Susanna S Park

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 979. doi:

The effect of combined PlGF and VEGF inhibition on vascular leakage and inflammation in experimental murine models Open Access

Tine Van Bergen; Tjing-Tjing Hu; Isabelle Etienne; Geert Reyns; Jean Feyen

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 980. doi:

Long-acting FGF21 inhibits retinal vascular leakage in vivo and in vitro model Open Access

Yohei Tomita; Zhongjie Fu; Bertan Cakir; Ye Sun; Zongxiao Wang; Chi-Hsiu Liu; Shuo Huang; Alexander Poblete; Steve Cho; William Britton; Jing Chen; Lois E H Smith

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 981. doi:

Rod Visual Transduction is a Determinant of Diabetic Retinopathy Open Access

Rithwick Rajagopal; Sheng Zhang; Christina Oberlin; Clay F. Semenkovich

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 982. doi:

Neurovascular coupling impariment and vasomotor decline in a murine model of diabetic retinopathy Open Access

Botir T. Sagdullaev; Tamas Kovacs-Oller; Elena Ivanova

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 983. doi:

Myeloid cell dynamics in the mouse uveal tract during systemic inflammation Open Access

Samantha Dando; Paul G McMenamin

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 984. doi:

Inner Plexiform Layer-Specific Microglia Protect the Retinal Pigment Epitheilium in Retinal Degeneration Open Access

Chen Yu; Rose Mathew; Daniel R Saban

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 985. doi:

Neuropilin-1 Deficiency on Myeloid Cells Promotes a Pro-inflammatory Phenotype while Inhibiting Choroidal Neovascularization. Open Access

Elisabeth Andriessen; Francois Binet; Normand Beaulieu; Karine Beauchemin; Flavio A Rezende; Ariel M Wilson; Manuel Buscarlet; Frederik Fournier; Nicolas Tétreault; Przemyslaw Mike Sapieha

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 986. doi:

Interleukin-33 attenuates ocular angiogenesis through a mast cell dependent pathway. Open Access

Sofia Theodoropoulou; David Copland; Kepeng Ou; Jian Liu; Neal Millar; Andrew D Dick

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 987. doi:

A novel protective role of the C-type lectin Mincle in modulating inflammation and lesion size a mouse model of choroidal neovascularization. Open Access

Matt Rutar; Alice Brandli; Gene Venables; Erica L Fletcher; Christine Wells

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 988. doi:

SYSTEMIC INJECTION OF LOW DOSE LPS TRANSIENTLY IMPROVES THE RETINA FUNCTION AND STRUCTURE OF A MOUSE MODEL OF GEOGRAPHIC ATROPHY Open Access

Cristhian J Ildefonso; Brianna M Young

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 989. doi:

Title: Soluble oligomeric Amyloid-β induced retinal pigment epithelial degeneration requires non-canonical inflammsome activation Open Access

Siddharth Narendran; DAIPAYAN BANERJEE; Ivana Apicella; Shaobin Wang; Akhil Varshney; Shinichi Fukuda; Nagaraj Kerur; Bradley Gelfand; Jayakrishna Ambati

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 990. doi:

Biomarkers and endpoints for dry AMD trials Open Access

Srinivas R Sadda

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 991. doi:

Gene therapy trials for hereditary retinal degenerations Open Access

Jacque L Duncan

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 992. doi:

Artificial Intelligence approaches to enrich clinical trials populations Open Access

Ursula Schmidt-Erfurth

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 993. doi:

Development of Outcome Measurements for Studies of Macular Telangiectasia (Mac Tel) Type 2 Open Access

Emily Y Chew

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 994. doi:

Functional (visual fields) and structural (OCT) end points in clinical trials. Open Access

Donald C Hood

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 995. doi:

OCTA promise and challenges in clinical trials endpoint Open Access

David Huang

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 996. doi:

OCTA and beyond: Qualitative Revelations and Opportunities in Quantitative Imaging Open Access

Richard B Rosen

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 997. doi:

Regional transcriptome map of the adult rhesus macaque retina and RPE-choroid Open Access

Ameera Mungale; Temesgen D Fufa; David McGaughey; Congxiao Zhang; Arvydas Maminishkis; Sheldon S Miller; Brian Patrick Brooks; Robert Hufnagel

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 998. doi:

Mapping the Cis-Regulatory Architecture of the Human Retina Reveals Non-Coding Genetic Variation in Disease. Open Access

Timothy Cherry

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 999. doi:

De novo transcriptomes built from hundreds of human cornea, retina, and RPE RNA-seq samples identifies thousands of differentially expressed ocular specific gene transcripts and novel eye... Open Access

Vinay Swamy; Brian Patrick Brooks; Robert B Hufnagel; David McGaughey

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 1000. doi:

Cis-regulatory basis of sister cell type divergence in the vertebrate retina Open Access

Dan P Murphy; Andrew Hughes; Joseph C Corbo

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 1001. doi:

Optic nerve lipidomics reveal impaired glucosylsphingosine lipids pathway in glaucoma Open Access

Sanjoy K Bhattacharya; Muhammad Zain Chauhan; Ann Katrin Valencia; Maria Piqueras; Mabel Enriquez Algeciras

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 1002. doi:

Global RNA metabolic changes associated with a dominant-negative Crx mutation Open Access

Inez Oh; Shiming Chen

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 1003. doi:

Metabolomics in Age-related Macular Degeneration: The EYE-RISK Consortium Open Access

Ilhan Erkin Acar; Magda Meester; Laura Lorés de Motta; Daniel Pauleikhoff; Sascha Fauser; Carel C B Hoyng; Cecile DelCourt; Caroline C W Klaver; Tessel E Galesloot; Anneke I Den Hollander

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 1004. doi:

High-Fidelity Signal Transmission through Foveal Photoreceptors Open Access

Michael Tri Hoang Do; Gregory S. Bryman; Andreas Liu

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 1005. doi:

Ubiquitin-dependent regulation of transducin translocation during light and dark adaptation Open Access

Takahisa Furukawa; Taro Chaya; Ryotaro Tsutsumi; Leah Varner; Yamato Maeda

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 1006. doi:

Rod photoreceptor transition intensity between dominant time constants indicates a high rate of transducin activation Open Access

Trevor D Lamb; Timothy W Kraft

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 1007. doi:

Forward programming of photoreceptors from human induced pluripotent stem cells Open Access

Marta Zuzic; Anka Kempe; Mike O. Karl; Volker Busskamp

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 1008. doi:

Surprises from modulating GNAT1 and GNAT2 expression by CRISPR/Cas9-mediated gene targeting Open Access

Ching-Kang Jason Chen; Yu-Jiun Chen; Allison Shay

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 1009. doi:

Genetic Profiling of S- and M-Cone Photoreceptors Open Access

Wei Li; Vincent Kunze; Juan Angueyra; Li Jia

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 1010. doi:

Mapping the sensitivity of the central fovea with cone-targeted microstimulation Open Access

Niklas Domdei; Jenny Lorén Reiniger; Michael Linden; Frank G Holz; Wolf Maximilian Harmening

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 1011. doi:

Ebola virus persistence in aqueous humor and 12-month outcomes of cataract surgery in survivors of Ebola virus disease Open Access

Rachel Bishop; Robin Demi Ross; Jessica Shantha; Brent Hayek; Daniel Gradin; Benjamin Roberts; Ian Crozier; Elizabeth Higgs; Robert Dolo; Fred Amegashie; Gurcharan Singh; Kumar Nishant; Collin Van Ryn; Cavan Reilly; Steven Yeh; Allen O Eghrari

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 1012. doi:

Visual, Refractive and Anatomic Outcomes of Combined Versus Sequential Phacoemulsification and Vitrectomy in Patients with Epiretinal Membrane or Full-thickness Macular Hole Open Access

Harrison Dermer; Rehan Hussain; James Lin; Elizabeth A. Vanner; Luis J Haddock; Ninel Gregori

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 1013. doi:

Evaluation of Central Macular Thickness in low pulse energy Femtosecond Laser-assisted Cataract Surgery Open Access

Luca Schwarzenbacher; Daniel Schartmüller; Christina Leydolt; Gregor Sebastian Reiter; Rupert Menapace

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 1014. doi:

Improved Intraocular Lens Power Prediction using Ocular Coherence Tomography and Machine Learning Open Access

Chirag Shah; Darren Knight; Sumit Garg; Matthew Wade; Steven C Schallhorn; Stephen Hannan; James Tucker; Tanya Kim Huynh; Mitul C Mehta

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 1015. doi:

Intraocular Pressure (IOP) effects on self-sealing clear corneal incisions using 3D printed anterior segment model Open Access

Yann Bouremel; Christin Henein; Steve Brocchini; Peng Tee Khaw

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 1016. doi:

A Qualitative Approach to Understanding Reasons for Non-Participation and Barriers to Participation in School-Based Vision Programs Open Access

Hursuong Vongsachang; Amanda Inns; Alyssa Marie Kretz; Rani Mukherjee; David S Friedman; Michael X Repka; Megan E Collins

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 1017. doi:

The Landscape of Ophthalmologists and Optometrists in Ontario, Canada from 2011 to 2016 Open Access

Shicheng Jin; Sherif El-Defrawy; Jonathan A. Micieli; Yaping Jin; Peng Yan

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 1018. doi:

Prevalence and Determinants of Eyecare Utilization and Eyeglass Affordability in a Population-based Study of Ethnic Singaporeans Open Access

Preeti Gupta; Shivani Majithia; Alfred Gan; Eva K Fenwick; Stanley Poh; Charumathi Sabanayagam; Tien Y Wong; Yih Chung Tham; Ching-Yu Cheng; Ecosse Luc Lamoureux

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 1019. doi:

Establishing a collaborative model of glaucoma care in an Australian public hospital setting Open Access

Sharon Ann Bentley; Catherine Green; Linda Malesic; Tracy Siggins; Clare Escott; Maureen O'Keefe; Caroline Clarke

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 1020. doi:

Analysis of vision screening failures in a school-based vision program in Baltimore, MD Open Access

Alyssa Marie Kretz; Rachel Milante; Xinxing Guo; Amanda Inns; Moneesha Rani Mukherjee; David S Friedman; Michael X Repka; Megan E Collins

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 1021. doi:

Factors Influencing Patient Adherence to Diabetic Retinopathy Screening and Follow-up: An Exploratory Qualitative Study Open Access

Danielle Altman; Jennifer Jimenez; Chunyi Hsu; Sharon Hudson; Tiffany Luong; Donald S Fong

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 1022. doi:

Understanding barriers to glaucoma treatment adherence among patients in South India Open Access

OLIVIA KILLEEN; Manju Pillai; B. Udayakumar; Sujani Shroff; Menaka Vimalanathan; Juno Cho; Paula Anne Newman-Casey

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 1023. doi:

Correlated noise in extrastriate neurons of amblyopic monkeys Open Access

Bin Zhang; Ye Wang; Janice Marie Wensveen; Earl L Smith; Yuzo M Chino

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 1024. doi:

Fixation stability is not related to global motion deficits in amblyopia Open Access

Kimberly Meier; Miriam Spering; Deborah Giaschi

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 1026. doi:

Prehension planning deficits in adults with amblyopia Open Access

Simon Grant; Miriam Louise Conway

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 1027. doi:

Motor Skills and Self-Perception of 3- to 7-Year-Old Children with Deprivation Amblyopia Open Access

Eileen E Birch; Yolanda S Castañeda; Christina S Cheng-Patel; Sarah Morale [email protected]; Krista R Kelly; Serena Wang

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 1028. doi:

The Dose-Response Relationship with Intermittent Occlusion Therapy for Amblyopia Open Access

Jingyun Wang; Jing Jin; Ayesha Malik; Ruth Shoge; Siva Meiyeppen; Yi Pang; Kelly Yin; Megan Allen; Katharine Funari; Brandy Scombordi; Daniel Neely

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 1029. doi:

Cone Outer Segment Reflectance Entropy in Choroideremia Open Access

Andrew M. Huang; Robert F Cooper; Grace Vergilio; Jean Bennett; Albert M. Maguire; Tomas S Aleman; Jessica Ijams Wolfing Morgan

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 1030. doi:

Structure and Function of Dysflective Cones in Healthy and Diseased Eyes Open Access

Ethan Bensinger; Katharina G Foote; Jessica J. Wong; Jacque L Duncan; Austin Roorda

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 1031. doi:

Evaluation of Retinal Pigment Epithelium and Choroidal Neovascularization in Rats Using the Laser-scanning Optical-resolution Photoacoustic Microscopy Open Access

Fenghua Wang; Meichun Xiao; Cuixia Dai; Chuanqing Zhou; Xiaodong Sun

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 1032. doi:

Integrating AOSLO hardware and analysis using a database driven design Open Access

Stephen A Burns

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 1033. doi:

Comparison of objective measurements of retinal image motion from Tracking Scanning Laser Ophthalmoscopy (TSLO) with clinical tests of ocular motion Open Access

Nicole M Putnam; Vladimir Yevseyenkov; Ethan Bensinger; Caitlin Jomoc; Daniel Christensen; Isaiah Choy; David Bowin; Christy K Sheehy

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 1034. doi:

Fixational Eye Movements Following Concussion Open Access

Bianca Leonard; Min Zhang; Valerie Snyder; Cyndi Holland; Ethan Bensinger; Christy K Sheehy; Michael Collins; Anthony Kontos; Ethan A Rossi

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 1035. doi:

Saccadic eye movement abnormalities in Parkinson’s disease Open Access

Allen M Y Cheong; Hiu-Yan Lam; Larry A Abel; Paul Lee; Anne Chan; Yuk Fai Cheung; Leonard Li; Richard Li; Roger Li

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 1036. doi:

Overview of Gene Therapy in Anterior Segment Open Access

Alexander V Ljubimov

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 1037. doi:

Gene delivery to the trabecular meshwork for target validation, development of disease models, and the treatment of glaucoma Open Access

Abbot F Clark

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 1038. doi:

Self-delivery siRNA to prevent corneal scarring Open Access

Audrey M Bernstein

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 1039. doi:

Gene therapy to prevent corneal scarring Open Access

Rajiv R Mohan

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 1040. doi:

Harnessing the regulatory power of microRNAs to treat diseases of the anterior segment: adventures in nanotechnology. Open Access

Robert M Lavker

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 1041. doi:

Effects of visual acuity loss on running performance among visually impaired Paralympic athletes Open Access

Rob Chun; Robert W Massof; Chris Bradley; Peter Allen; Rianne Ravensbergen; David Mann

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 1043. doi:

Do vision functions predict Para Nordic skiing performance? Open Access

Amritha Stalin; Marieke Creese; Kristine Dalton

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 1044. doi:

Can vision functions predict Para Alpine skiing performance? Open Access

Kristine Dalton; Amritha Stalin; Marieke Creese

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 1045. doi:

Visual Function and Visuo-Motor Coordination in Acute Stroke Open Access

Chamini Wijesundera; Algis J Vingrys; Yu Xiang George Kong; Tissa Wijeratne; Sheila Gillard Crewther

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 1046. doi:

Association of home hazards with the falls rates per time or per step in glaucoma Open Access

Aleksandra Mihailovic; Ayodeji Sotimehin; David S Friedman; Sheila K West; Pradeep Y Ramulu

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 1047. doi:

Gait Patterns in Severe Peripheral Field Loss due to Retinitis Pigmentosa Open Access

Joshua R Ehrlich; Abigail Kumagai; Yooree Chung; Andrew Chen; Phuoc Nguyen; Sherry Day; Donna Wicker; Ashley Howson; Shirin E Hassan; David C Musch; James D Weiland; Sayoko Eileen Moroi; Lauro Ojeda

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 1048. doi:

A Binocular Scotoma Causes a Person to Adopt a Safe Street-Crossing Strategy Open Access

Shirin E Hassan

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 1049. doi:

The Impact of Vision Status on Spatial Localization Open Access

YINGZI XIONG; Douglas Addleman; Peggy Nelson; Gordon E Legge

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 1050. doi:

Effect of Observer Motion on the Visibility of Architectural Features with Simulated Acuity Reduction Open Access

Siyun Liu; Quan Lei; Brent Carpenter; Gordon E Legge; Daniel Kersten

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 1051. doi:

Implications of monocular vision for racing drivers Open Access

julien Adrian; Johan Le Brun; Neil Miller; Jose Alain Sahel; Gérard Saillant; Bahram Bodaghi

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 1052. doi:

Assessment of visual acuity requirements for autonomous vehicle operation. Open Access

Daliya Dzhaber; Alan Shan; Ryan S Meshkin; Marjan Tofigh; Gelareh Vakili; Allen O Eghrari

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 1053. doi:

Driving performance and behavior adaptation of glaucoma patients Open Access

Colas Nils Authié; Ariel Zenouda; Julien Adrian; Marco Lombardi; Emmanuelle Brasnu; Pascale Hamard; Jose Alain Sahel; CRISTOPHE BAUDOUIN; Antoine Labbé

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 1054. doi:

How do simulated central vision loss and distraction affect the detection of hazards by older and younger drivers? Open Access

Ting Zhang; Steven Savage; Alex R Bowers

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 1055. doi:

Pilot study of a tactile hazard warning device for drivers with hemianopia Open Access

Alex R Bowers; Roman Hoelzl; Lorenz Steckhan; Olivia Herzog; Steven Savage; Christian Lehsing

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 1056. doi:

Association between driving avoidance at night and the severity of primary-open angle glaucoma in a Japanese population. Open Access

Akiko Hanyuda; Kenya Yuki; Sachiko Tanabe-Awano; Takeshi Ono; Daisuke Shiba; Kazuo Tsubota

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 1057. doi:

Pilot study of an auditory scanning reminder system for drivers with hemianopia Open Access

Jing Xu; Birte Emmermann; Olivia Herzog; Garrett Swan; Christian Lehsing; Alex R Bowers

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 1058. doi:

Specificity and retention of perceptual learning in children with visual impairment Open Access

Bianca Huurneman; Nienke Boonstra; Jeroen Goossens

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 1059. doi:

Analysis of Visual Outcomes in Children with Primary Congenital Glaucoma Open Access

Lei Fang; Xing Liu; Yin Hu; Yi Min Zhong

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 1060. doi:

Face perception - can it be improved in age-related macular degeneration and Stargardt disease? Open Access

Iain R Wilson; Stephen Lloyd Hicks; Susan M. Downes; Robert E MacLaren

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 1061. doi:

Word neighborhood size is not a limiting factor of reading speed with central field loss Open Access

Aurelie Calabrese; Lauren Sauvan; Carlos Aguilar; Eric Castet

Investigative Ophthalmology & Visual Science July 2019, Vol.60, 1062. doi:

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