Select a back issue
Select a back issue
  • Alerts
    User Alerts
    You are adding an alert for:
    Investigative Ophthalmology & Visual Science
    You will receive an email whenever new content is published in the Investigative Ophthalmology & Visual Science. You can manage this and all other alerts in My Account
    The alert will be sent to:
    ×
    This feature is available to authenticated users only.
    Sign In or Create an Account ×
Page 1 of 4

ARVO Annual Meeting Abstract

Long-read technologies unravel hidden inversion-duplication in a family with choroideremia Open Access
Susanne Roosing; Zeinab Fadaie; Tuomo Mantere; Ronny Derks; Amber den Ouden; Michael Kwint; Luke O'Gorman; Dyon Valkenburg; Carel Hoyng; Christian Gilissen; Lisenka E.L.M. Vissers; Marcel Nelen; Frans P.M. Cremers; Kornelia Neveling; Alexander Hoischen
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 1. doi:
Sequencing of ABCA4 in a large international Stargardt disease cohort reveals novel pathogenic deep intronic variation and a variant enriched in Ireland. Open Access
Laura Whelan; Adrian Dockery; Mubeen Khan; Zelia Corradi; Kirk A.J. Stephenson; Julia Zhu; Stephanie Cornelis; Jacqueline Turner; James J O'Byrne; Giuliana Silvestri; David J Keegan; Paul F Kenna; Susanne Roosing; Claire-Marie Dhaenens; Frans P.M. Cremers; G. Jane Farrar
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 2. doi:
Whole genome sequencing and UMI-4C provide novel insights into the genetic architecture and mechanisms underlying North Carolina macular dystrophy, a cis-regulatory disease Open Access
Stijn Van de Sompele; Eva D'haene; Thijs Van der Snickt; Sarah Vergult; Petra Liskova; Fadi Shaya; Karen Nuytemans; Jeffery M Vance; Margaret A Pericak-Vance; Andrea L Vincent; Steven Agemy; Kent W Small; Elfride De Baere
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 3. doi:
A Deep Intronic Substitution in CNGB3 is One of the Major Causes of Achromatopsia among Jewish Patients Open Access
Hamzah Aweidah; Manar Salameh; Claudia Yahalom; Anat Blumenfeld; Michal Macarov; Nicole Weisschuh; Susanne Kohl; Eyal Banin; Dror Sharon
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 4. doi:
Intronic variant in sonic hedgehog associated with autosomal dominant pediatric cataract, myopic astigmatism, familial exudative vitreoretinopathy, and primary open-angle glaucoma Open Access
Stuart W. Tompson; Kristina N. Whisenhunt; Alex W Hewitt; David A Mackey; Terri L Young
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 5. doi:
ABCA4 c.859-25A>G, a frequent Palestinian founder mutation associated with retinal dystrophy, results in multiple splice defects Open Access
Manar Salameh; Zelia Corradi; Mubeen Khan; Ajoy Vincent; Elise Heon; Rebekkah Hitti-Malin; Yahya AlSwaiti; Eyal Banin; Claire-Marie Dhaenens; Dror Sharon; Alaa AlTalbishi; Frans P.M. Cremers
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 6. doi:
Deletion of conserved non-coding elements downstream of foxc1a in zebrafish affects its expression and produces ocular phenotype Open Access
Jesus Jose Ferre Fernandez; Sanaa Muheisen; Samuel Thompson; Ross F Collery; Elena V Semina
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 7. doi:
Correlation between photoreceptor density in adaptive optics imaging with retinal structure and sensitivity in autoimmune retinopathy Open Access
Wataru Matsumiya; Amir Akhavanrezayat; Gunay Uludag; Cigdem Yasar; Hashem Ghoraba; Azadeh Mobasserian; Irmak Karaca; Brandon Chau Lam; Brandon Pham; Jaclyn Joyce Hwang; Rubbia Afridi; Muhammad Sohail Halim; Diana V Do; Yasir J Sepah; Quan Dong Nguyen
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 8. doi:
Adaptive-glasses Full-Field OCT for high-resolution retinal imaging over a large field-of-view Open Access
Pedro Mecê; Jules Scholler; Kassandra Groux; Yao Cai; Michel Paques; Kate Grieve; Claude Boccara
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 9. doi:
Actively stabilized AOOCT with independent focus adjustment for optimal AOSLO-based eye tracking Open Access
Sanam Mozaffari; Fabio Feroldi; Francesco LaRocca; Pavan K. Tiruveedhula; Patrick Gregory; B. Hyle Park; Austin John Roorda
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 10. doi:
Using Adaptive Optics to Evaluate Photoreceptor Regularity in a Porcine Laser Model Mimicking Age-Related Macular Degeneration Open Access
Rishabh Gupta; Francesca BARONE; Dara Baker; Devika Bose; Haig Pakhchanian; Irina Bunea; Arvydas Maminishkis; Davide Ortolan; Joe Phillips; Ruchi Sharma; Juan Amaral; David Gamm; Kapil Bharti
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 11. doi:
Impaired cone function in drusen regions revealed by phase-sensitive adaptive optics OCT Open Access
Zhuolin Liu; Furu Zhang; Daniel Hammer
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 12. doi:
Automated Vessel Segmentation in Adaptive Optics – Optical Coherence Tomography Images Open Access
Christopher Le; Dongyi Wang; Ricardo Villanueva; Zhuolin Liu; Daniel Hammer; Osamah Saeedi
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 13. doi:
Ultrastructural Changes of Hard Exudates in Retinal Vein Occlusion Examined by Offset Pinhole Adaptive Optics Scanning Light Ophthalmoscope Open Access
Shin Kadomoto; Yuki Muraoka; Akihito Uji; Masaharu Ishikura; Naomi Nishigori; Akitaka Tsujikawa
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 14. doi:
Improved Adaptive Optics Scanning Laser Ophthalmoscope and lens for gonioscopic imaging Open Access
Alessandra Carmichael-Martins; Thomas Gast; Brett King; Stephen A Burns
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 15. doi:
Ultrafast adaptive optics for imaging the living human eye Open Access
Yan Liu; James Alan Crowell; Kazuhiro Kurokawa; Hae Won Jung; Ayoub Lassoued; Marcel Bernucci; Donald Thomas Miller
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 16. doi:
Red Blood Cell Velocity Variability in Small Retinal Vessels Open Access
Raymond Warner; Thomas Gast; Kaitlyn Sapoznik; Alessandra Carmichael-Martins; Stephen A Burns
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 17. doi:
In vivo longitudinal assessment of cone photoreceptor density in age-related macular degeneration Open Access
Xiaolin Wang; Srinivas R Sadda; David Sarraf; Yuhua Zhang
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 18. doi:
Variability in high resolution cone spacing measures in eyes with retinitis pigmentosa Open Access
Lawrence Chan; Jessica Wong; Shane Griffin; Stephanie K Lynch; Travis C Porco; Austin John Roorda; Jacque L Duncan
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 19. doi:
Neurovascular coupling in the human retina evaluated by adaptive optics ophthalmoscopy Open Access
Daniela Castro Farías; Carlo Lavia; Florence Rossant; Michel Paques
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 20. doi:
Retinal microcystoid lacunae in autosomal dominant optic atrophy: relation to visual function Open Access
Christina Eckmann-Hansen; Michael Larsen
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 21. doi:
Adaptive optics scanning laser ophthalmoscopy (AOSLO) measures in USH2A-related retinal degeneration Open Access
Jacque L Duncan; Wendi Liang; Joseph Carroll; Jenna Cava; Jessica Wong; Michel Michaelides; Angelos Kalitzeos; Isabelle Audo; Kate Grieve; Natalie Norberg; Michel Paques; Allison Ayala; Travis C Porco
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 22. doi:
AO-OCT imaging of the retina with a pyramid wavefront sensor Open Access
Elisabeth Brunner; Julia Shatokhina; Muhammad Faizan Shirazi; Wolfgang Drexler; Rainer A. Leitgeb; Christoph K Hitzenberger; Ronny Ramlau; Michael Pircher
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 23. doi:
Comparison of adaptive optics scanning laser ophthalmoscopy and high-magnification scanning laser ophthalmoscopy Open Access
Dirk-Uwe G Bartsch; Mahima Jhingan; Qais Zawaydeh; Melina Cavichini Cordeiro; William R Freeman
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 24. doi:
Imaging of Presumed Displaced Retinal Ganglion Cells in the Living Human Retina Open Access
Mary Marte; Kazuhiro Kurokawa; Hae Won Jung; Yan Liu; Marcel Bernucci; Brett King; Donald Thomas Miller
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 25. doi:
Direct comparison of photoreceptor reflectivity measurements using simultaneous adaptive optics SLO and OCT Open Access
Andrew J. Bower; Tao Liu; Zhuolin Liu; Nancy Aguilera; Joanne Li; Rongwen Lu; John Giannini; Steven Cornelissen; Alfredo Dubra; Daniel Hammer; Johnny Tam
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 26. doi:
Clinical retinal oximetry with visible-light optical coherence tomography Open Access
Ian Rubinoff; Roman V. Kuranov; Yuanbo Wang; Zeinab Ghassabi; Gadi Wollstein; Behnam Tayebi; Hiroshi Ishikawa; Joel S Schuman; Hao Zhang
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 27. doi:
Optoretinography in the human retina using AOOCT and AOSLO-based eye tracking Open Access
Fabio Feroldi; Sanam Mozaffari; Francesco LaRocca; Pavan K. Tiruveedhula; Patrick Gregory; B. Hyle Park; Austin John Roorda
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 28. doi:
Assessing peripapillary surface macrophage density in eyes with glaucomatous damage using enface OCT Open Access
Toco Yuen Ping Chui; Maria Virginia Castanos Toral; Davis B. Zhou; Oscar Otero-Marquez; Justin V Migacz; Rachel E Linderman; Joseph Carroll; Donald C Hood; Robert Ritch; Richard B Rosen
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 29. doi:
In vivo imaging of inner plexiform layer (IPL) stratification in the human retina with visible light Optical Coherence Tomography (OCT) Open Access
Vivek J Srinivasan; Tingwei Zhang; Aaron Michael Kho
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 30. doi:
Values of Retinoblastoma Survivors and Parents Regarding Treatment Outcomes: A Qualitative Study Open Access
Ana Janic; Ajoy Vincent; Jennifer Stinson; Helen Dimaras
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 31. doi:
Oral HIF-2α inhibitor belzutifan for ocular von Hippel-Lindau (VHL) disease Open Access
Henry Wiley; Hanna R. Coleman; Eric Jonasch; Ramaprasad Srinivasan; Frede Donskov; Anders Kruse; Jodi K. Maranchie; Jay Chhablani; Tobias Else; Hakan Demirci; Benjamin L. Maughan; Mary Elizabeth Hartnett; Rodolfo F. Perini; Eric K. Park; Emily Y Chew
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 32. doi:
Comprehensive somatic copy number analysis using the aqueous humor liquid biopsy for retinoblastoma Open Access
Ashley Polski; Mary Elizabeth Kim; Liya Xu; Rishvanth K. Prabakar; Jonathan Kim; Rachana Shah; Rima Jubran; Peter Kuhn; James Hicks; Jesse L Berry
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 33. doi:
NIGHT study: natural progression of choroideremia Open Access
Byron L Lam; Robert E MacLaren; M. Dominik Fischer; Frank G Holz; Mark E Pennesi; David G Birch; Eeva-Marja Sankila; Isabelleanne Meunier; Kimberly E Stepien; Juliana M.F. Sallum; Cindy Lu; Jiajun Liu; Dan Yoon
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 34. doi:
Likelihood of Germline Mutation with Solitary Retinoblastoma Based on Tumor Location at Presentation Open Access
Philip Dockery; Megan Ruben; Antonio Yaghy; Carol Shields
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 35. doi:
A Computational Model of BAP-1 Expression in Uveal Melanoma Reveals Early-Onset Mutagenesis Open Access
Ogul Ersin Uner; Thonnie Rose O See; Eszter Szalai; Hans E Grossniklaus; Gustav Stålhammar
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 36. doi:
Expression of immune checkpoint LAG3 is associated with high risk uveal melanoma Open Access
Zahra Souri; Gre Luyten; Martine J Jager
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 37. doi:
Evaluation of Anti-Cancer Properties of Selective Histone Deacetylase 6 Inhibitors in Uveal Melanoma Open Access
Husvinee Sundaramurthi; Sandra G. Mulero; Melody Buckley; Josep M. Piulats; Breandan N Kennedy
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 38. doi:
Clinical characteristics and gene expression profile status in young patients with uveal melanoma: Collaborative Ocular Oncology Group study #2 (COOG2) study Open Access
Ekaterina Semenova; Christina Decatur; Amy C Schefler; Thomas Aaberg; Brian Marr; Zelia Correa; J. William Harbour; Prithvi Mruthyunjaya; Miguel Materin
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 39. doi:
Outcomes of The Cancer Genome Atlas (TCGA) Classification in Uveal Melanoma by Patient Age in 1001 Eyes Open Access
Zaynab Sajjadi; Zeynep Bas; Eileen L. Mayro; Arupa Ganguly; Carol Shields
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 40. doi:
Vitreoretinal lymphoma: clinical features, treatment, and outcomes Open Access
Dimitrios Ntentakis; Saghar Bagheri; Mark P. McGarrey; Lakshmi Nayak; Lucia Sobrin; Ivana K Kim; Dean Eliott; Mary E Aronow
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 41. doi:
Inhibition of soluble adenylyl cyclase (sAC) rescues defective melanosomal pH and pigmentation in oculocutaneous albinism type 2 (OCA2). Open Access
Jonathan Zippin; Maftuna Yusupova; Kasumasa Wakamatsu; Dalee Zhou
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 42. doi:
Genome-wide transcriptional responses of human choroidal endothelial cells to corticosteroids as a model for central serous chorioretinopathy Open Access
Joost Brinks; Elon van Dijk; Szymon Kielbasa; Hailang Mei; Paul Quax; Onno Meijer; Camiel J F Boon
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 43. doi:
Development of AU-011 for Choroidal Metastasis Open Access
Cadmus C Rich; Anneli Savinainen; Rhonda Kines
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 44. doi:
Ocular findings in patients undergoing cancer treatment Open Access
Jacqueline Coblentz; Christina Mastromonaco; Sabrina Bergeron; Georges Nassrallah; Ana Beatriz Dias; Anelise Savaris Dias; Miguel N Burnier
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 45. doi:
Refractive ametropia induced by contact lenses changes OCT-A macular indices Open Access
Andrew Carkeet; Barsha Lal; Scott A Read; David Alonso-Caneiro
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 46. doi:
Cone mosaic integrity in choroideremia following gene augmentation via subretinal injection of AAV2-hCHM Open Access
Jessica Ijams Wolfing Morgan; Yu You Jiang; Leona W Serrano; Denise J Pearson; Jean Bennett; Albert M Maguire; Tomas S Aleman
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 47. doi:
Visualization of the human retinal pigment epithelial cell mosaic with and without adaptive optics using late phase indocyanine green imaging Open Access
Joanne Li; Tao Liu; Jianfei Liu; Andrew J. Bower; John Giannini; Rongwen Lu; Nancy Aguilera; Johnny Tam
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 48. doi:
Foveal cone mosaic disruptions in diabetic subjects Open Access
Vamsi Parimi; Ann E Elsner; Brittany Walker; Robert Gilbert; Thomas Gast; Stephen A Burns
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 49. doi:
Adaptive optics fluorescence lifetime ophthalmoscopy of iGlucoSnFR-TS suggests increased glucose in RPE of rho-/- compared to healthy mice Open Access
Karteek Kunala; Yunlu Xue; Khang Huynh; Qiang Yang; Keith Parkins; Samuel Steven; Alfredo Dubra; Connie L. Cepko; Jennifer J Hunter
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 50. doi:
Variation of human cone spectral composition with eccentricity Open Access
Vimal Prabhu Pandiyan; Sierra Schleufer; Hongyi Yan; Xiaoyun Jiang; James Kuchenbecker; Maureen Neitz; Jay Neitz; Ramkumar Sabesan
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 51. doi:
Measuring S, M, and L cone sensitivities in the living human eye using phase-sensitive AO-OCT Open Access
Marcel Bernucci; Kazuhiro Kurokawa; Yan Liu; Furu Zhang; James Alan Crowell; Donald Thomas Miller
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 52. doi:
Obesity and Risk of Age-Related Eye Diseases: A Systematic Review of Prospective Population-based Studies Open Access
Clarissa Ng Yin Ling; Su Chi Lim; Jost Jonas; Charumathi Sabanayagam
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 53. doi:
Ethnic differences in the prevalence of ocular disease among hospitalized older adults with obesity Open Access
Amy Chen; Aditya Uppuluri; Marco A Zarbin; Neelakshi Bhagat
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 54. doi:
Trends in prevalence of eye diseases, utilisation of eye health care services and medications after entering residential aged care in Australia Open Access
Jyoti Khadka; Julie Ratcliffe; Gillian Caughey; Steve Wesselingh; Maria Inacio
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 55. doi:
The Association of Traffic-Related Air Pollution and Perfusion of the Peripapillary Retina in African Americans Open Access
Dominic Joseph Grisafe; Meredith Franklin; Darryl Nousome; Roberta McKean-Cowdin; Bruce Burkemper; Mina Torres; Ryuna Chang; Jae Lee; Grace Richter; Rohit Varma
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 56. doi:
Smoking, Lung Disease and Other Factors Associated with the Long Anterior Zonule (LAZ) Trait Open Access
Daniel K Roberts; Tricia L Newman; Janice M McMahon; Christina E Morettin; Mary Flynn Roberts
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 57. doi:
Social Determinants of Health Data for Patients with Eye Conditions in a Nationwide Data Repository Open Access
Terrence Lee; Alison Chan; John McDermott; Bita Shahrvini; Gordon Ye; Amy M. Sitapati; Camille Nebeker; Bharanidharan Radha Saseendrakumar; Sally Liu Baxter
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 58. doi:
Visual impairment and 3-year change in cognitive function in the Canadian Longitudinal Study on Aging Open Access
Alyssa Grant; Marie-Josée Aubin; Ralf Buhrmann; Marie-Jeanne Kergoat; Ellen E. Freeman
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 59. doi:
Cardiovascular Disease Risk Factors in U.S. Adults with Vision Impairment Open Access
Elizabeth Ann Lundeen; Minchul Kim; Isabel Mendez; Jinan Saaddine
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 60. doi:
The 3-Year Incidence of Visual Impairment and its Risk Factors in Canada: The Canadian Longitudinal Study on Aging Open Access
Zaina Kahiel; Marie-Josée Aubin; Ralf Buhrmann; Marie-Jeanne Kergoat; Ellen E. Freeman
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 61. doi:
Visual Function, Physical Function, and Activities of Daily Living in Two Aging Communities Open Access
Xinxing Guo; Yanan Dong; Lubaina Tayeb Arsiwala; Aleksandra Mihailovic; Pradeep Y Ramulu; Richey A Sharrett; Alison Abraham
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 62. doi:
Post-cataract surgery health outcomes in frail older patients Open Access
Varshini Varadaraj; Shang-En Chung; Orla C Sheehan; David Roth; Oliver D Schein; Karen Bandeen-Roche; Bonnielin K Swenor
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 63. doi:
Predictors of Inadequate Health Literacy Among Comprehensive Ophthalmology Patients Open Access
Saif Hamdan; Sapna Gangaputra; Eric Brown
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 64. doi:
Gender Gap in the Award Recipients of the Association for Research in Vision and Ophthalmology Open Access
Sanyam Ratan; Anne Xuan-Lan Nguyen; Ankita Biyani; Xuan-Vi Trinh; Yang Sun; Solin Saleh; Albert Y. Wu
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 65. doi:
Normative Distribution of Optical Coherence Tomography Retinal Features and Associations with Visual Function in Older Adults (from the Eye Determinants of Cognition Study) Open Access
Yanan Dong; Xinxing Guo; Alison Abraham; Richey A Sharrett; Lubaina Tayeb Arsiwala; Pradeep Y Ramulu; Aleksandra Mihailovic
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 66. doi:
Burden and Predictors of Undetected Eye Disease in Adult African Americans: The African American Eye Disease Study (AFEDS) Open Access
Nathan Dhablania; Mina Torres; Bruce Burkemper; Roberta McKean-Cowdin; Rohit Varma
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 67. doi:
Incidence of ocular diseases as related to hyperuricemia and gout based on Taiwan Biobank Open Access
Hung-Liang Pai; Meng-Tien Hsieh; Jing-Yang Huang; Han-Hsin Chang; Jeng-Yuan Chiou; David Pei-Cheng Lin
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 68. doi:
Retinal Photography in a Cohort of Urban Middle-Aged Adults Open Access
Alisa T Thavikulwat; Tiarnan D L Keenan; Panos G Christakis; David Peprah; Alan B Zonderman; Michele K Evans; Emily Y Chew
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 69. doi:
Exfoliation Syndrome in the Baja Verapaz Region of Guatemala Open Access
Chase Paulson; Samuel C. Thomas; Orlando Gonzalez; Sam Taylor; Cole Swiston; Jennifer Herrick; Karen Curtin; Craig J. Chaya; Brian Craig Stagg; Barbara M Wirostko
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 70. doi:
Association of Non-Melanoma Skin Cancer with Exfoliation Syndrome: The Utah Project of Exfoliation Syndrome Open Access
Christian James Pompoco; Chase Paulson; Samuel C. Taylor; Brian Craig Stagg; Robert Ritch; Jae H Kang; Janey L Wiggs; Louis R Pasquale; Karen Curtin; Barbara M Wirostko
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 71. doi:
NON INVASIVE EVALUATION OF THE AGING OF THE CRISTALINE LENS IN NORMALS AND DIABETICS Open Access
Paloma Rodríguez-Esteve; Marta Gonzalez-Hernandez; Alicia Pareja-Rios; Manuel Gonzalez de la Rosa
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 72. doi:
Axial Length and Its Associations in a Very Old Population. The Ural Very Old Study Open Access
Jost Jonas; Gyulli Kazakbaeva; Songhomitra Panda-Jonas; Rinat M Zainullin; Timur M Gilmanshin; Mukharram Bikbov
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 73. doi:
Associations between a Strabismus Diagnosis and Subsequent Mental Health Disorders in Children and Adolescents Open Access
Kevin Firl; Rahul Raiker; Haig Pakhchanian; David Belyea
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 74. doi:
Risk of myocardial infarction following diagnosis of a common ophthalmic disease: analysis of a longitudinal record-linkage study of over 350,000 patients from the UK. Open Access
Siegfried Wagner; Mario Cortina-Borja; Alastair K Denniston; Fintan Hughes; Nikolas Pontikos; Jugnoo Rahi; Pearse Keane
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 75. doi:
Eyelid Cancer Prevalence and Associated Factors in the AAO IRIS® Registry Open Access
Zeynep Bas; James Sharpe; Antonio Yaghy; Qiang (Ed) Zhang; Carol Shields; Leslie Hyman
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 76. doi:
Risk Factors for lens opacities in African Americans: The African American Eye Disease Study (AFEDS) Open Access
Bruce Burkemper; Roberta McKean-Cowdin; Xuejuan Jiang; Mina Torres; Rohit Varma
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 77. doi:
Baltimore Homeless Eye Disease Study Open Access
zeshan tariq; Alfred Vinnett; Jason Alvarez; Nneoma Okezie; Laura Andrews; Moran Roni Levin; Mona Kaleem
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 78. doi:
Exploring the What-If-Tool as a solution for machine learning explainability in clinical practice Open Access
Ritvij Singh; Abdallah Abbas; Sara Beqiri; Edward Korot; Robbert Struyven; Peter Woodward-Court; Pearse Keane
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 79. doi:
Retinal mitochondrial flavoprotein fluorescence in non-exudative or neovascular age-related macular degeneration Open Access
Sarunas Petras Daugirdas; Jessica Carolina Liu; Justin Muste; Amogh Iyer; Collin Rich; Rishi P Singh
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 80. doi:
A multimodal deep learning (DL) model to predict visual acuity response in the CATT study Open Access
Jelena Novosel; Neha Anegondi; Jian Dai; Ebenezer Daniel; Glenn J Jaffe; Maureen G Maguire; Jeffrey R Willis
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 81. doi:
A pilot study using machine learning (ML) to predict treatment outcomes in patients with neovascular age-related macular degeneration (nAMD) using phase 2 trial data Open Access
Yusuke Kikuchi; Michael Kawczynski; Neha Anegondi; Jian Dai; Carlos Quezada Ruiz
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 82. doi:
Calcific nodules within retinal drusen in age-related macular degeneration: Association with disease progression and impact on microperimetry Open Access
Kai Lyn Goh; Robyn H Guymer; Lauren A.B. Hodgson; Zhichao Wu
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 83. doi:
The influence of Quantity and Location of Hyperpigmentary Abnormalities on the Progression of Age-related Macular Degeneration Open Access
Himeesh Kumar; Liubov Robman; Galina Makeyeva; Xavier Hadoux; Maxime Jannaud; Lauren A.B. Hodgson; Kai Lyn Goh; Tony Pham; Robyn H Guymer; Zhichao Wu
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 84. doi:
Beyond federated learning: fusion strategies for diabetic retinopathy screening algorithms trained from different device types Open Access
SANDIPAN CHAKROBORTY; Krunalkumar Ramanbhai Patel; Alexander Freytag
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 85. doi:
Hierarchical curriculum learning for robust automated detection of low-prevalence retinal disease features: application to reticular pseudodrusen Open Access
Cristina González-Gonzalo; Eric F. Thee; Bart Liefers; Coen de Vente; Caroline C. W. Klaver; Clara I. Sánchez
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 86. doi:
Reference Standards for Assessment of Fluid in Neovascular Age-Related Macular Degeneration (nAMD) Open Access
Kunal Malik; Melissa Lanser; Jeong W Pak; Mark Banghart; Barbara Blodi; Amitha Domalpally
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 87. doi:
Baseline choriocapillaris flow deficits in treatment-naïve neovascular AMD correlate with number of subsequent anti-VEGF injections Open Access
Peter L. Nesper; Nicholas Konopek; Janice X. Ong; Amani A Fawzi
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 88. doi:
Validation of an autonomous AI-based diagnostic system for holistic maculopathy screening in a routine occupational health checkup context Open Access
Miguel Zapata; Sandra Banderas; Didac Royo; Anniken Bures; Cecilia Salinas; Octavi Font
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 89. doi:
Bilateral evolution of OCT biomarkers in dry AMD: long-term follow up study Open Access
Anindya Samanta; Supriya Arora; Mahima Jhingan; Sumit Singh; Sohani Amarasekera; Davide Tucci; Carlo Cagini; Marco Lupidi; Jay Chhablani
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 90. doi:
Prediction of Causative Genes in Inherited Retinal Disorders from Fundus photography and Fundus Autofluorescence Imaging Utilising Deep Learning Techniques Open Access
Yu Fujinami-Yokokawa; Hideki Ninomiya; Xiao liu; Lizhu Yang; Nikolas Pontikos; Kazutoshi Yoshitake; Takeshi Iwata; Yasunori Sato; Takeshi Hashimoto; Hiroaki Miyata; Kaoru Fujinami
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 91. doi:
Deep learning survival analysis on the progression to late AMD in the Age-Related Eye Disease Study Open Access
Gregory Cyrus Ghahramani; Matthew Brendel; Qingyu Chen; Tiarnan D L Keenan; Kun Chen; Emily Y Chew; Zhiyong Lu; Yifan Peng; Fei Wang
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 92. doi:
IMPAIREMENT OF CHORIORETINAL VASCULATURE IN PATIENTS WITH INTERMEDIATE AGE-RELATED MACULAR DEGENERATION Open Access
Rita Flores; Angela Carneiro; Guilherme Nery; Sandra Tenreiro; Miguel Seabra
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 93. doi:
Prospective Validation of a Bi-modal Retinal Image Intelligent Analysis System at a District Hospital Open Access
Guanzheng Wang; Xu Zhang; Jonathan Liu; Rui Wang; Dan Cao; Chuanfeng Lv; Guotong Xie; Xin Liu
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 94. doi:
Enhanced visualization of hyperpigmentation using near infrared multiply scattered light imaging Open Access
Matthew S Muller; Ann E Elsner; Joel A Papay
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 95. doi:
Automated Machine Learning Prediction of Visual Acuity from Preoperative OCT Images After Macular Hole Surgery Open Access
Alexandre Lachance; Fares Antaki; Mélanie Hébert; Serge Bourgault; Mathieu Caissie; Eric Tourville; Ali Dirani
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 96. doi:
Relationship between Intraretinal and Subretinal Fluid with Visual Acuity in Patients with Neovascular Age-Related macular Degeneration Treated with Anti-Vascular Endothelial Growth Factor Open Access
Amogh Iyer; Justin Muste; Aneesha Kalur; Rishi P Singh
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 97. doi:
Utilizing Higher-Order Quantitative SD-OCT Biomarkers in a Machine Learning Prediction Model for the Development of Subfoveal Geographic Atrophy in Age-Related Macular Degeneration Open Access
Annapurna Hanumanthu; Kubra Sarici; Joseph Roy Abraham; Jon Whitney; Leina Lunasco; Duriye Damla Sevgi; Hasan Cetin; Sunil K. Srivastava; Jamie Reese; Justis P Ehlers
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 98. doi:
Does retinal fluid correlate with OCTA characteristics of choroidal neovascular membranes? Open Access
Markus Schranz; Reinhard Told; Valentin Hacker; Philipp Ken Roberts; Gregor Sebastian Reiter; Adrian Reumueller; Wolf-Dieter Vogl; Hrvoje Bogunovic; Stefan Sacu; Ursula Schmidt-Erfurth
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 99. doi:
Deep learning based binary image quality algorithm for low-cost fundus imaging system in remote care settings Open Access
Taylor Shagam; Minhaj Alam; Simon Bello; Laura Tracewell; Bryan Rogoff; Patricia Sha; Noli Graves; Dorothy Hitchmoth; Mary K Durbin; Niranchana Manivannan
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 100. doi:
OCTA biomarkers of CNV secondary to aged-related macular degeneration following intravitreal aflibercept Open Access
Eung Suk Kim; Jong Beom Park; Kiyoung Kim; Seung-Young Yu
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 101. doi:
Risk factors for progression of Age-related Macular Degeneration: Amish Eye Study Open Access
Muneeswar Gupta Nittala; Jyotsna Maram; Federico Covi; Swetha Bindu Velaga; Jonathan L Haines; Margaret A Pericak-Vance; Dwight Stambolian; Srinivas R Sadda
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 102. doi:
Alterations of the Ganglion Cell Complex in Age-Related Macular Degeneration: an AMISH Eye Study Analysis Open Access
Swetha Bindu Velaga; GAGAN SINGH; Muneeswar Nittala; Dwight Stambolian; Margaret A Pericak-Vance; Jonathan L Haines; Srinivas R Sadda
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 103. doi:
Impact of Residual Subretinal Fluid Volumes on Treatment Outcomes in a SRF-tolerant Treat & Extend Regimen Open Access
Christoph Grechenig; Gregor Sebastian Reiter; Sophie Riedl; Jennifer Arnold; Robyn H Guymer; Bianca S Gerendas; Hrvoje Bogunovic; Ursula Schmidt-Erfurth
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 104. doi:
Correlation of AI-quantified retinal morphology with topographic function in neovascular AMD Open Access
Sophie Riedl; Markus Schranz; Oliver Leingang; Gregor Sebastian Reiter; Christoph Grechenig; Wolf-Dieter Vogl; Mustafa Arikan; Philipp Ken Roberts; Irene Steiner; Hrvoje Bogunovic; Ursula Schmidt-Erfurth
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 105. doi:
Predictors of retinal pigment epithelium tear development after treatment for neovascular age-related macular degeneration using swept source optical coherence tomography angiography Open Access
Satoshi Yasuhara; Manabu Miyata; Sotaro Ooto; Hiroshi Tamura; Naoko Ueda; Akihito Uji; Yuki Muraoka; Masahiro Miyake; Ayako Takahashi; Tomotaka Wakazono; Kenji Yamashiro; Akitaka Tsujikawa
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 106. doi:
Automated diagnosis and grading of dry age-related macular degeneration using optical coherence tomography imaging Open Access
Mohamed Elsharkawy; Ahmed Sharafeldeen; Ahmed Soliman; Fahmi Khalifa; Rafael Widjajahakim; Andy Switala; Ahmed Elnakib; Shlomit Schaal; Harpal Singh Sandhu; Johanna M Seddon; Ayman El-Baz
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 107. doi:
Prevalence and Characteristics of Reticular Pseudodrusen in the Carotenoids in Age-Related Eye Disease Study 2 (CAREDS2) Open Access
Jeong W Pak; Spencer Cleland; Amitha Domalpally; Zhe Liu; Barbara Blodi; Steven T Bailey; Karen M Gehrs; Robert B Wallace; Lesley Tinker; Julie A Mares
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 108. doi:
Automated fovea and optic disc detection in the presence of occlusions in Fundus SLO Images Open Access
Marc Stadelmann; Agata Mosinska; Mathias Gallardo; Raphael Sznitman; Marion Munk; Stefanos Apostolopoulos; Carlos Ciller; Sandro De Zanet
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 109. doi:
The ILUVIEN implant in DME – are we leaving it too late? Open Access
Salman Naveed Sadiq; Maged Habib
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 110. doi:
Retinal Image Curation Using Deep Learning Open Access
Nancy Barrett; Bin Li; Ellen TA Dobson; Barbara Blodi; Kevin W Eliceiri; Amitha Domalpally
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 111. doi:
Ganglion Cell Layer Thickness Change in Neovascular Age-Related Macular Degeneration Treated with Anti-VEGF Injections Open Access
Dimosthenis Mantopoulos; Hetal Ray; George Sanchez; Russell Pokroy; Daniel Roth
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 112. doi:
Optimizing inference performance of a fundus image quality neural network model for edge computing using TensorFlow Lite Open Access
Hugang Ren; Simon Bello; Minhaj Nur Alam; Niranchana Manivannan; Taylor Shagam; Neil D'Souza
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 113. doi:
Artificial Intelligence-based Detection of Diabetic Retinopathy using Retinal Imaging and Traditional Risk Factors Open Access
Sajib Kumar Saha; Matthew Watson; Cirous Dehghani; Katie Edwards; Nicola Pritchard; Anthony Russell; Rayaz A Malik; Nathan Efron; Shaun Frost; Yogesan Kanagasingam
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 114. doi:
Automated screening of moderately severe and severe nonproliferative diabetic retinopathy (NPDR) from 7-field color fundus photographs (7F-CFP) using deep learning (DL) Open Access
Fethallah Benmansour; Qi Yang; Dimitrios Damopoulos; Neha Anegondi; Ales Neubert; Jelena Novosel; Beatriz Garcia Armendariz; Daniela Ferrara
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 115. doi:
Detecting Severity of Experimental Autoimmune Uveitis in Mice from Retinal Fundus Photographs using Deep Learning Open Access
Jian Sun; xiaoqin huang; Siamak Yousefi
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 116. doi:
A Deep-Learning Based Algorithm for Automated Segmentation of Geographic Atrophy in Swept-Source Optical Coherence Tomography Open Access
Varsha Pramil; Luis De Sisternes; Lars Omlor; Warren Lewis; Sophie Kubach; Harris Asad Sheikh; Mary K Durbin; Nadia K Waheed
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 117. doi:
Automated Machine Learning Model For The Classification Of Retinal Diseases From Ultra-Widefield Pseudocolor Fundus Images Open Access
Fares Antaki; Razek Georges Coussa; Karim Hammamji; Mikael Sebag; Renaud Duval
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 118. doi:
Unsupervised deep learning for grading age-related macular degeneration using retinal fundus images Open Access
Glenn Yiu; Baladitya Yellapragada; Sascha Hornauer; Kiersten Snyder; Stella Yu
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 119. doi:
Combining artificial intelligence and robotics: a semi-automated optical coherence tomography-based approach for posterior eye disease screening Open Access
Ailin Song; Pablo Ortiz; Mark Draelos; Stefanie G Schuman; Glenn J Jaffe; Sina Farsiu; Joseph Izatt; Ryan P McNabb; Anthony N Kuo
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 120. doi:
Identification of initial events leading to outer retinal atrophy in age-related macular degeneration using deep learning quantifications Open Access
Gregor Sebastian Reiter; Sophie Riedl; Antoine Rivail; Julia Mai; Wolf-Dieter Vogl; Christoph Grechenig; Zhichao Wu; Robyn H Guymer; Hrvoje Bogunovic; Ursula Schmidt-Erfurth
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 121. doi:
Deep learning-based automated fluid quantification in clinical routine OCT images in neovascular AMD over 5 years Open Access
Bianca S Gerendas; Amir Sadeghipour; Martin Michl; Felix Goldbach; Georgios Mylonas; Thomas Alten; Oliver Leingang; Stefan Sacu; Hrvoje Bogunovic; Ursula Schmidt-Erfurth
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 122. doi:
Detecting conversion to exudative neovascular age-related macular degeneration using machine learning Open Access
Sandrine Zweifel; Maximilian Wiest; Anton Mislevics; Daryna Peremot; Andrey Bondarenko; Katrin Fasler; Timothy Hamann
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 123. doi:
Performance of an Artificial Intelligence model in retinal fluid quantification for patients with diabetic macular edema and retinal vein occlusions. Open Access
Abdul-Hadi Kaakour; Weilin Song; Aneesha Kalur; Amogh Iyer; Justin Muste; Rishi P Singh
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 124. doi:
HDF-Net: A Novel Convolutional Neural Network Approach of Image and Non-image Data Integration for Treatment Outcome Prediction in Neovascular Age-Related Macular Degeneration Open Access
Tsai-Chu Yeh; An-Chun Luo; Yu-Shan Deng; Yu-Hsien Lee; Po-Han Chang; Chun-Ju Lin; Ming-Chi Tai; Yu-Bai Chou
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 125. doi:
Prediction of best-corrected visual acuity (BCVA) from color fundus photography (CFP) using deep learning (DL) Open Access
Michael Kawczynski; Neha Anegondi; Qi Yang; Jeffrey R Willis; Thomas Bengtsson; Simon S. Gao; Jian Dai
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 126. doi:
Prediction of ranibizumab injection frequency in patients with macular edema due to retinal vein occlusion during as-needed dosing period of BRAVO and CRUISE Phase 3 trials Open Access
Yun Li; Verena Steffen; Fethallah Benmansour; Michel Friesenhahn; Zdenka Haskova
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 127. doi:
Topographic Effects on AI-Quantified Regional Progression in the FILLY Trial of Pegcetacoplan (APL-2) for Treatment of Geographic Atrophy Secondary to AMD Open Access
Wolf-Dieter Vogl; Hrvoje Bogunovic; Julia Mai; Gregor Sebastian Reiter; Sophie Riedl; Dmitrii Lachinov; Ursula Schmidt-Erfurth
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 128. doi:
Predictive Identification of the Fastest Progressing Geographic Atrophy Lesions based on Deep Learning in the Phase 2 FILLY clinical trial of Pegcetacoplan Open Access
Hrvoje Bogunovic; Dmitrii Lachinov; Julia Mai; Gregor Sebastian Reiter; Sophie Riedl; Wolf-Dieter Vogl; Ursula Schmidt-Erfurth
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 129. doi:
Topographic conversion model of outer retinal atrophy progression in intermediate age-related macular degeneration using deep learning Open Access
Antoine Rivail; Gregor Sebastian Reiter; Sophie Riedl; Julia Mai; Wolf-Dieter Vogl; Christoph Grechenig; Zhichao Wu; Robyn H Guymer; Ursula Schmidt-Erfurth; Hrvoje Bogunovic
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 130. doi:
Prediction of Best-Corrected Visual Acuity from Optical Coherence Tomography in Patients with Neovascular Age-Related Macular Degeneration Using Deep Learning Open Access
Anam Akhlaq; Saleema A. Kherani; Craig Jones; Peter A Campochiaro; Tin Yan Liu
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 131. doi:
A novel, online platform for tracking amblyopia patients: cohort description and initial results Open Access
Tinh Le; Basak Can; Adam Peiffer; Hayley Klein; Maryo Kohen; Faruk Orge
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 132. doi:
Effects of demographics on the dilation of preschool children during the eye exam Open Access
Joannah M Vaughan; Talitha Dale; Daniel Herrera
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 133. doi:
Crowding effect in children with and without amblyopia Open Access
Kristine Kalnica-Dorosenko; Aiga Svede
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 134. doi:
Corneal cystine crystal deposition: Online medical education can significantly improve knowledge, competence and confidence diagnosing and treating ocular manifestations of nephrotic cyst... Open Access
Siggi Trier; Pakinam Aboulsaoud; John Maeglin; Stephanie Cherqui; Paul C Grimm; Rachel J Bishop
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 135. doi:
Maturation of hand-eye coordination in typically developing children and adolescents Open Access
Ewa Niechwiej-Szwedo; Susana Wu; Lisa Christian
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 136. doi:
Prescribing Patterns for Hyperopia Open Access
Marjean T Kulp; Elise B Ciner; G. Lynn Mitchell; Gui-Shuang Ying; Mae Millicent Peterseim; Anastasia Alex; Christine Allison; Sandra Block; T Rowan Candy; David Granet; Richard W Hertle; Bruce Moore; Deborah A Orel-Bixler; Tawna L Roberts; Shira Robbins; Gayathri Srinivasan
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 137. doi:
New 3D printed Adjustable Eyeglasses to Address the Global Burden of Pediatric Refractive Errors Open Access
Mari Ogino; Nathan Oslie; Donny Suh; Gabe Linke; James Hermsen
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 138. doi:
Naso-temporal asymmetry for global motion perception in children with deprivation amblyopia Open Access
Arijit Chakraborty; Krista R Kelly; Eileen E Birch; Benjamin Thompson
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 139. doi:
Applying Normal PedEyeQ Thresholds to Define Reduced Quality of Life in Children with Visual Impairment Open Access
Suzanne M Wernimont; David A Leske; Sarah R Hatt; Yolanda S Castañeda; Christina S Cheng-Patel; Erick D Bothun; Eileen E Birch; Jonathan M Holmes
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 140. doi:
Effect of Age on Reduced Child-Reported Eye-Related Quality of Life and Functional Vision in Strabismus Open Access
Sarah R Hatt; David A Leske; Suzanne M Wernimont; Yolanda S Castañeda; Christina S Cheng-Patel; Erick D Bothun; Eileen E Birch; Jonathan M Holmes
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 141. doi:
A New Treatment Questionnaire for Children with Eye Conditions Open Access
David A Leske; Sarah R Hatt; Suzanne M Wernimont; Yolanda S Castañeda; Christina S Cheng-Patel; Erick D Bothun; Eileen E Birch; Jonathan M Holmes
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 142. doi:
Children with amblyopia have deficiency in searching real world images Open Access
PremNandhini Satgunam; Krishnaveni Nagarajan; Gang Luo
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 143. doi:
Fixation and Saccadic Abnormalities in Amblyopic Patients With and Without Nystagmus Open Access
Dhiksha Balaji; Jordan Murray; Fatema F Ghasia
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 144. doi:
Preparation of the Early Glasses Study: a randomized, controlled trial investigating the effect of early glasses for high refractive error on the development of amblyopia Open Access
Annelies Bruinenberg; Mandy Nordmann; Wijnanda L Asjes - Tydeman; Daisy Sanders; Rinske van Ommen; Janine Benjamins; Jeanne-Marie Hament; Chantal WF Wiersma-Hartman; Inge Tissen; Nienke Boonstra; Huibert Jan Simonsz
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 145. doi:
Virtual Vision Outreach Program: Give Kids Sight Day (GKSD) 2020 Open Access
Rujuta Gore; Connie Wu; Michael Lai; Caitlin Green; Rebecca Elias; Barry Wasserman
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 146. doi:
Characterization of Higher Visual Function Deficits (HVFDs) with a Question Inventory in children with Cerebral Visual Impairment (CVI) and good visual acuity (VA) Open Access
Arvind Chandna; Saeideh Ghahghaei; Susan Foster
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 147. doi:
EUSCREEN APP calculates the cost-effectiveness of vision screening programs, taking local circumstances into account Open Access
Huibert Jan Simonsz; Hans Hoeve; Eveline Heijnsdijk; Jan Kik; Anna Horwood; Inger Úhlen; Gwen Carr; Mandy Nordmann; Harry de Koning
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 148. doi:
Impact of a Vision Screening and Spectacle Correction Program on Educational Development in Preschoolers from Low-Income Communities Open Access
Lauren Hennein; Christopher Lees; April Nakayoshi; Alejandra G. de Alba Campomanes
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 149. doi:
Ophthalmological findings in adolescents born moderate-to-late preterm Open Access
Alexandra Lind; Eva Aring; Titus Ovik; Arzu Karatepe; Lina Raffa; Zoran Popovic; Jovanna Dahlgren; Marita Andersson Gronlund
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 150. doi:
Performance of the Spot Vision Screener in Children with Down Syndrome and Other Special Needs Open Access
Lucy Mudie; Emily McCourt; Robert Enzenauer
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 151. doi:
Intergenerational utility in parents of children with amblyopia Open Access
Geertje van der Sterre; H.M. van der Meulen-Schot; Ellen Abma-Bustraan; Huibert Jan Simonsz
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 152. doi:
Contrast sensitivity assessment in children with brain injury. Open Access
Nazia M Alam; Scott William Joseph Mooney; Leul Tesfaye; Glen Thomas Prusky
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 153. doi:
Impact of Amblyopia on the Function of Stereo- and Motion-Selective Clusters in Human Extrastriate Cortex Open Access
Shahin Nasr; Bryan Kennedy; Amanda Nabasaliza; Peter Bex; Roger BH Tootell; David G Hunter
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 154. doi:
Cluster-Randomized Controlled Trial of School-Based Visual Screening for Kindergarten Children Open Access
Mayu Nishimura; Daphne Maurer; Agnes M.F. Wong
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 155. doi:
Long-term Stability of Eccentric Fixation Measured by OCT in Children with Unilateral Amblyopia Open Access
Jingyun Wang; Sharon Lehman; Dorothy Hendricks; Jonathan Salvin; Jing Jin
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 156. doi:
Fixation Eye Movements in Amblyopia during Binocular and Dichoptic viewing conditions Open Access
Fatema F Ghasia; Jordan Murray; Kiran Garg
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 157. doi:
Intact hand kinematics in anisometropic children during visually-guided reaching Open Access
Jeffrey Hunter; Reed Jost; Cynthia Beauchamp; Lori Dao; Becky Luu; Ewa Niechwiej-Szwedo; Krista R Kelly
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 158. doi:
The effect of patching and gaming therapy on visual acuity in children with amblyopia and influence on quality of life Open Access
Aveen Kadhum; Emily Tan; Janna Bruijning; Maurits V Joosse; Huibert Jan Simonsz; Sjoukje E Loudon
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 159. doi:
Perceptual learning with attention tasks improves contrast sensitivity in V1 of human adults with amblyopia Open Access
Chuan Hou; Gabriela Acevedo Munares
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 160. doi:
Risk of Acquired Retinal Detachment in Children with Ocular Coloboma Open Access
Sila Bal; Monte Mills; Lauren Tomlinson; Elana Meer; Gui-Shuang Ying; Gil Binenbaum
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 161. doi:
Factors Affecting Rates of Genetic Testing for Inherited Retinal Degenerations Open Access
Peter Yu Cheng Zhao; Kari E Branham; Dana Schlegel; Abigail T Fahim; Thiran Jayasundera
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 162. doi:
TNF-α Inhibitors and Risk of Age-related Macular Degeneration in Patients with Rheumatoid Arthritis Open Access
Elizabeth Dugan; Aisaku Nakamura; Harpal Sandhu
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 163. doi:
A prospective survey assessing patient experiences and understanding of advertised stem cell therapies for retinal disease. Open Access
Hailey Robles-Holmes; Jayanth Sridhar; Nicolas A. Yannuzzi; Marissa Patel; Jodi Hwang
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 164. doi:
Association of Environmental Factors with Neovascular Age-Related Macular Degeneration (nvAMD) using the Intelligent Research in Sight (IRIS)® Registry Open Access
Matthew Hunt; Steven Saraf; Yewlin Chee; Yue Wu; Cecilia S Lee; Aaron Y Lee; Michael B Manookin
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 165. doi:
Evaluation of geographic atrophy secondary to age-related macular degeneration in clinical practice: analysis of the American Academy of Ophthalmology IRIS® Registry Open Access
M. Ali Khan; Ehsan Rahimy; Ray Hsieh; Ramiro Ribiero; Allen Ho; Nancy M Holekamp
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 166. doi:
Time Series Trends for Rhegmatogenous Retinal Detachment Repair, Retinal Break Treatment, and Posterior Vitreous Detachment using the Intelligent Research In Sight (IRIS®) Registry Open Access
Steven Sepehr Saraf; Megan Lacy; Matthew Hunt; Aaron Y Lee; Cecilia S Lee; Yewlin Chee
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 167. doi:
Pentosan Polysulfate Sodium Maculopathy: A Big Data Study of Patients with Interstitial Cystitis Open Access
Eric Bernard Desjarlais; Judy E Kim
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 168. doi:
Discontinuation and Loss to Follow-Up Rates in Clinical Trials of Intravitreal Anti-Vascular Endothelial Growth Factor Injections Open Access
Tatiana Rosenblatt; Nadim Rayess; Ahmad Al Moujahed; Prithvi Mruthyunjaya
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 169. doi:
Investigation of the use of drusen as a biomarker for age-related macular degeneration reveals shared genetic risk in the Amish Open Access
Michael David Osterman; Yeunjoo E Song; Muneeswar Nittala; Srinivas R Sadda; William K Scott; Dwight Stambolian; Margaret A Pericak-Vance; Jonathan L Haines
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 170. doi:
Acquired vitelliform macular degeneration, characteristics and challenges of managing subretinal fluid Open Access
Joseph Juliano; Sagar Patel; Hossein Ameri
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 171. doi:
Systemic Disease Associations with Angioid Streaks using a U.S. National Healthcare Database Open Access
Yafeng Li; Jennifer Beth Nadelmann; Brendan McGeehan; Brian L VanderBeek
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 172. doi:
Smartphone based Remote Monitoring of Vision in macular disease enables early detection of worsening pathology and need for intravitreal therapy Open Access
Meriam Islam; Stafford Sansome; Radha Das; Marko Lukic; Kelvin Yi Chong Teo; Gavin Siew Wei Tan; Konstantinos Balaskas; Peter Thomas; Lucas M. Bachmann; Andrew M. Schimel; Dawn A Sim
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 173. doi:
Does cataract surgery increase the risk of future development of late AMD? A nested case-control study from the AREDS2 and AREDS2 Follow-On studies Open Access
Susan Vitale; Elvira Agron; Sanjeeb Bhandari; David Peprah; Maureen C Farrell; Traci E Clemons; Tiarnan D L Keenan; Amitha Domalpally; Emily Y Chew
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 174. doi:
Tutorial on Biostatistics: Receiver-Operating Characteristic (ROC) Analysis for Correlated Eye Data Open Access
Bernard Rosner; Gui-Shuang Ying; Maureen G Maguire; Robert Glynn
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 175. doi:
Assessing risk factors for retinal vein occlusions using the NIH All of Us Research Program Open Access
John J McDermott IV; Terrence Lee; Alison Chan; Gordon Ye; Bita Shahrvini; Bharanidharan Radha Saseendrakumar; Sally Liu Baxter
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 176. doi:
Collaborative Development of a Novel Patient-centred App (MyEyeSite): Transforming Researcher Access to Rare Inherited Retinal Disease Data Open Access
Rose Gilbert; Dayyanah Sumodhee; Nikolas Pontikos; Catherine Hollyhead; Angus Patrick; Jocelyn Cammack; Sam Scarles; Sabrina Van Der Smissen; Rodrigo Young; Nick Nettleton; Andrew Webster
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 177. doi:
Ascertainment of Age-related Macular Degeneration (AMD) Status in the Second Carotenoids in Age-Related Eye Disease Study (CAREDS2), an Ancillary Study of the Women’s Health Initiative (W... Open Access
Zhe Liu; Amitha Domalpally; Barbara Blodi; Steven Bailey; Karen M. Gehrs; Ron Gangnon; Kim Wood; Tom Lawler; Yao Liu; Robert B Wallace; Cynthia Hurtenbach; Lesley Tinker; Courtney Blomme; Jennifer Maykoski; Julie A Mares
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 178. doi:
Target 5000: Evolution of the Irish National Program for Inherited Retinal Degenerations Open Access
Kirk A.J. Stephenson; Julia Zhu; Niamh Wynne; Rebecca Cairns; Adrian Dockery; Laura Whelan; Emma Duignan; Jacqueline Turner; James J O'Byrne; Laura Brady; Giuliana Silvestri; Paul F Kenna; G. Jane Farrar; David J Keegan
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 179. doi:
Profiles of women with choroideremia diagnosis codes Open Access
Lisa Vinikoor-Imler; D. Cortney Hayflinger; Dan Yoon; Susan Eaton
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 180. doi:
Association of Age-related Macular Degeneration with Exfoliation Syndrome: The Utah Project on Exfoliation Syndrome Open Access
Samuel Taylor; Chase Paulson; Christian James Pompoco; Karen Curtin; Brian Craig Stagg; Robert Ritch; Barbara M Wirostko
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 181. doi:
Cost of Illness Study of Inherited Retinal Diseases in the USA and Canada Open Access
Avril Daly; Simone Cheung; Orla Galvin
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 182. doi:
KNP-301, a dual inhibitor of the complement pathway and angiogenesis, effectively suppresses angiogenesis and atrophy Open Access
Eu Ddeum (Philip) Chung; Donggeon Kim; Soomin Ryu; Jihoon Chang; Byoung Chul Lee
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 183. doi:
Analytical Similarity Assessment of a Ranibizumab Biosimilar SB11 to Reference Product Open Access
Se Joon Woo; Hyerim Park; Yunjung Chae; Jihyeon Han; Eunji Kim; Un Na; Beomchan Kim
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 184. doi:
Allele-selective reduction of P23H-mutant rhodopsin with stereopure oligonucleotides rescues phenotype associated with retinitis pigmentosa in preclinical models Open Access
Michael Byrne; Vinod Vathipadickal; Lankai Guo; Yuan Yin; Hailin Yang; Richard Looby; Lauren Norwood; James W Fransen; archana jalligampala; Jennifer Noel; Chandra Vargeese; Maureen A McCall
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 185. doi:
Suppression of Murine Choroidal and Retinal Neovascularization by Risuteganib and the Accompanying Transcriptome Changes in the OIR Retina Open Access
Zixuan Shao; Sean F. Hackett; Raquel Formica; Yogita Kanan; Dan Zhou; John Y Park; Hampar L Karageozian; Vicken H Karageozian; Peter A Campochiaro; Julia A. Kornfield
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 186. doi:
Oral Administration of the Complement Factor D Inhibitor Danicopan (ALXN2040) in Preclinical Studies Demonstrates High and Sustained Drug Concentrations in Posterior Ocular Tissues for th... Open Access
David Boyer; Jose Rivera; Ya-Ping Ko; Steven D Podos; Mark Cartwright; Xiang Gao; Jason Wiles; Mingjun Huang
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 187. doi:
Brolucizumab’s actions on unchallenged or VEGFA-exposed retinal endothelial cells Open Access
Heidrun L Deissler; Catharina Busch; Armin Wolf; Matus Rehak
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 188. doi:
The Port Delivery System with ranibizumab (PDS)—a new paradigm for long-acting retinal drug delivery Open Access
Jay M Stewart; Tammy Tam; Judit Horvath; Jennifer Rea; Giulio Barteselli; Shrirang Ranade
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 189. doi:
A hypothermia mimetic molecule (zr17-2) reduces ganglion cell death and prevents electroretinogram distortion following intraorbital optic nerve crush (IONC) in the rat Open Access
Ignacio M Larrayoz; Daniela S Contartese; Manuel Rey-Funes; Rafael Peláez; Manuel Soliño; Juan Carlos Fernández; Nicolás Sebastián Ciranna; Anibal Sarotto; Veronica B Dorfman; Juan J López-Costa; José M Zapico; Ana Ramos; Beatriz de Pascual-Teresa; Cesar Fabián Loidl; Alfredo Martínez
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 190. doi:
Sterculic acid treatment promotes cell survival of retinal pigment epithelium cells in a multi-pathway dependent manner. Open Access
Rafael Peláez; Ana Pariente; Álvaro Pérez-Sala; Rodrigo Ochoa; Ignacio M Larrayoz
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 191. doi:
In vitro characterization of ranibizumab release from the Port Delivery System Open Access
Stefan Yohe; Katie Maass; Judit Horvath; Jennifer Rea; Giulio Barteselli; Shrirang Ranade
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 192. doi:
How do RA and SLE patients differ while on long-term hydroxychloroquine therapy? Open Access
Manlong Xu; Ian M MacDonald
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 193. doi:
A 1-Month Toxicology and Biodistribution NHP Pilot Study Evaluating a Single Subretinal Bilateral Administration of SPVN06 - A Novel AAV-Based Gene Therapy for the Treatment of Rod-Cone D... Open Access
Melanie MARIE; Myriam Marussig; Pierre-Axel VINOT; Thomas VIHTELIC; Ryan F. Boyd; Lauren KNUPP; Jennifer LAMOUREUX; Thierry D Leveillard; Jose Alain Sahel; Florence LORGET
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 194. doi:
Cytoprotective Effects of Brimonidine in an Induced Pluripotent Stem Cell (iPSC)-Derived Retinal Pigment Epithelium (RPE) Model of Age-Related Macular Degeneration (AMD) Open Access
Lori-Ann Christie; Ruchi Sharma; Malika Nimmagadda; Davide Ortolan; Genqing Liang; Kiyoharu Joshua Miyagishima; Mitalee Tamhane; Mike Ly; William Change; Richard Graham; Shaoxin Feng; Francisco J Lopez; Brenda Smith; Kapil Bharti
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 195. doi:
Systemic Antisense Oligonucleotide Inhibition of Complement Factor B for Treatment of Geographic Atrophy: Results of a Placebo-controlled Phase 1 Dose-Escalation Study Open Access
David S Boyer; Jayashree Sahni; Sascha Fauser; Richard Geary; Eugene Schneider; Michael McCaleb
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 196. doi:
Patient preferences in retinal drug delivery Open Access
Nicholas Palmer; Brandon Jacobs; Trupti Shetty; Helen Dimaras; Amir Reza Hajrasouliha; Denis Jusufbegovic; Timothy William Corson
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 197. doi:
Highly-enriched retinal pigment epithelium and photoreceptor genes without circadian variability Open Access
Nemanja Milićević; Cristina Sandu; Jacoline B. ten Brink; Aldo Jongejan; Perry Moerland; Soile Nymark; Marie-Paule Felder-Schmittbuhl; Arthur A.B. Bergen
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 198. doi:
Sustained delivery of griseofulvin by polymeric microparticles for neovascular eye disease treatment Open Access
Dhawal Chobisa; Kamakshi Sishtla; Timothy William Corson; Yoon Yeo
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 199. doi:
Duration of Effect of a Single Intravitreal Injection of a Sustained-Release Formulation of Abicipar Pegol Compared to a Bolus Dose of Aflibercept in a Rabbit Model of Persistent Retinal ... Open Access
David Lutz; Mingting Tian; Lisa Hernandez; Hong Shen; Ashutosh Kulkarni; Hongwen Rivers; Gerry Rodrigues
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 200. doi:
Determination of a No Observed Effect Level (NOEL) for Beta Glucans following a Single Intravitreal Administration to Female Dutch Belted Rabbits Open Access
Vladimir Bantseev; Sara Parker; Roxanne Andaya; Chris Schuetz; Brian Christian; Paul E Miller; Helen Booler; Melissa Schutten
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 201. doi:
To Analyze the dead space syringe for intra-vitreous injections Open Access
Anderson Teixeira; Isadora Silva; Amelia Pereira; Camila Salaroli
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 202. doi:
VITAMIN D3 AND MESO-ZEAXANTHIN COMBINATION PROTECTS HUMAN RETINAL PIGMENTED EPITHELIAL CELLS IN AMD Open Access
Claudio Bucolo; Francesca Lazzara; Federica Conti; Chiara B M Platania; Filippo Drago
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 203. doi:
An Aflibercept-derived Mini-VEGF-Trap as a Potential Next-Generation VEGF Inhibitor Open Access
Raymond Wilson Leidich; Krunal Patel; Ashique Rafique; Annabel Romero Hernandez; Matthew Franklin; Miguel Lazo; Aynur Hermann; Gitanjali Sharma; Yiming Zhao; Hunter Chen; Nina Liu; Michael Rosconi; Carmelo Romano; William Olson; Neil Stahl
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 204. doi:
Single Subcutaneous Dose of Anti-Angiogenesis Drug Safely Suppresses Choroidal Neovascularization Comparable to Intravitreal Aflibercept Open Access
Jeffrey Cleland; Rishi Sharma; Santiago Appiani; Minghao Sun; Justin Prater; Siva Kambhampati; David Culp
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 205. doi:
Maturation of retinal pigment epithelium cells in vitro enhances the endogenous antioxidant defense system Open Access
Jenni J. Hakkarainen; Olga Vergun; Anita K. Ghosh; Simon Kaja
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 206. doi:
Targeting the Notch transcriptional activation complex with a novel PRAG1 inhibitor to attenuate reactive gliosis Open Access
Ryan Alexander Gallo; Tanya T Kelley; Galina Dvoriantchikova; Steven H Lang; Acadia Hanne Marlene Moeyersoms; David T Tse; Stephan Schürer; Daniel Pelaez
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 207. doi:
Developing Methotrexate-Induced Immune Tolerance in a Rabbit Model of Persistent Retinal Vascular Leak Open Access
Lisa Hernandez-Denlinger; Matthew Mason; Mingting Tian; Lydia Andrews-Jones; Mihir Shah; Keith A Luhrs; Gerry Rodrigues; Lori-Ann Christie
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 208. doi:
Translational Read-through of a KCNJ13 nonsense mutation with ELX-01 and ELX-03 results in functional Kir7.1 channels Open Access
HENRY ZAPATA GALARZA; Pawan K Shahi; Doug W. McMillin; Daniel K. Crawford; Bikash R Pattnaik
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 209. doi:
A Fully Human Monoclonal Antibody Targeting c-KIT is a Potent Inhibitor of Choroidal Neovascularization in Murine Model of Neovascular Age-Related Macular Degeneration Open Access
songyi seo; Jin-Ock Kim; Koung Li Kim; Se Joon Woo; Sang Gyu Park; wonhee suh
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 210. doi:
Toxicity of p(g3T2) Polymer on Human Retinal Pigment Epithelium Cells Open Access
Seyed Omid Mohammadi; Meg LaRocca; Johannes Gladisch; Eleni Stavrinidou; Magnus Berggren; Cristina Kenney; Ken Lin
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 211. doi:
Delivering topical IL-33 with a cell penetrating peptide to treat neovascular age-related macular degeneration. Open Access
Chloe Naomi Thomas; Sofia Theodoropoulou; Christopher Weston; Jessica Cooklin; Dave Copland; Andrew D Dick; Alastair K Denniston; Lisa J Hill
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 212. doi:
Intra-Vitreal Delivery of Interferon Gamma Using Porous Silicon for Treatment of Age-Related Macular Degeneration (AMD). Open Access
Shachi Saluja; Lars Esser; Mark Richardson; Jayesh Bellare; Nicolas H Voelcker
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 213. doi:
Uncovering novel drugs that restore vision by combining biological and computational drug discovery processes Open Access
Justine O'Brien; Andrea Cerquone Perpetuini; Robert Scoffin; Breandan N Kennedy
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 214. doi:
Progression of Age-Related Macular Degeneration measured by Ultrawidefield Imaging in the Age-Related Eye Disease Study 2 10 Year Follow-On Open Access
Claire E Malley; Elvira Agron; Tiarnan D L Keenan; Traci E Clemons; Amitha Domalpally; Tunde Peto; Wai T Wong; Emily Y Chew
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 215. doi:
Pentosan Polysulfate Maculopathy: Prospective Longitudinal Study of Disease Course after Drug Cessation Open Access
Aaron Lindeke-Myers; Riley Lyons; Judy Brower; Nieraj Jain
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 216. doi:
Drug-Gene Association Analysis to Identify Novel AMD Therapeutics Open Access
Edward Xie; Urooba Nadeem; Bingqing Xie; Mark D Souza; Hugo Adrian Barba; David Dao; Dinanath Sulakhe; Dimitra Skondra
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 217. doi:
Phase 1 Study of an Intravitreal Axitinib Hydrogel-based Implant for the Treatment of Neovascular Age-Related Macular Degeneration (nAMD) Open Access
James Gilbert Wong; Andrew Chang; Robyn H Guymer; Sanjeewa Wickremasinghe; Erin Reilly; Nicki Bell; Srilatha Vantipalli; Andrew A Moshfeghi; Michael H Goldstein
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 218. doi:
Pharmacokinetics and target engagement of intravitreal administration of ANX007, an anti-C1q antibody fragment, in nonhuman primates Open Access
Anita Grover; Sethu Sankaranarayanan; Vidhu Mathur; Poojan Suri; Yaisa Andrews-Zwilling; Kirsten Mease; Lori K Taylor; Ellen Cahir-McFarland; Sanjay Keswani; Ted Yednock
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 219. doi:
VEGFR2 trafficking by KIF13B is a novel therapeutic target for wet AMD Open Access
Kaori Yamada; Christopher Zhou
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 220. doi:
Differentially expressed microRNAs within extracellular vesicles of a functionally active subpopulation of endothelial colony forming cells demonstrate neurovasculotrophic effects Open Access
Kyle Vincent Marra; Edith Aguilar; Ayumi Ouchi; Guoqin Wei; Martin Friedlander
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 221. doi:
A 12-week, Randomized, Double-blind, Placebo-controlled Study Assessing the Efficacy of EGHB010, a Standardized Extract of Paeoniae radix and Glycyrrhizae radix, in Patients with Early Ag... Open Access
Joo Young Kim; Mirinae Kim; Rae Young Kim; Wookyung Park; Young-Hoon Park
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 222. doi:
Developing P2X7 antagonists for the treatment of inflammatory eye disease Open Access
Marika Zuanon; Andrea Brancale; Mark Thomas Young
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 223. doi:
Therapeutic Efficacy of BIOP 653.1 in a Rabbit Model of Chronic Retinal Neovascularization Open Access
Eric Bankaitis; Daniel White; Justin Prater; David Culp
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 224. doi:
sFLT01-anti-ANG2: a Novel Potent Inhibitor as a Next-generation Anti-angiogenic Molecule Open Access
Hamid Ahmadieh; Hamid Latifi-navid; Zahra-Soheila Soheili; Mehdi Sadeghi; Shahram Samiei; Ehsan Ranaei Pirmardan; Sepideh Taghizadeh; Shahriar Arab; Saman Tajbakhsh; Fahimeh Zakeri
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 225. doi:
Cell-penetrable, protease-resistant αA-crystallin-derived peptide chaperone triggers cell stress response pathways and alleviates β-amyloid engendered toxicity in Caenorhabditis elegans Open Access
Puttur Santhoshkumar; Swati Srivastava; SUNDARARAJAN MAHALINGAM; Gina Broitman-Maduro; Madhu Sudhana Saddala; Akash Verma; Anil Bhatia; Jay S Kirkwood; Morris F Maduro; K Krishna Sharma
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 226. doi:
Immunogenicity profile of the Port Delivery System with ranibizumab in patients with nAMD Open Access
Margaret Chang; Katie Maass; Galin Jackson Spicer; Natasha Singh; Steven Blotner; Mauricio Maia
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 227. doi:
EYS809 Non-Viral Gene Therapy to Improve Convenience and Outcomes in Wet AMD Open Access
Elise Orhan; Karine Bigot; Pauline Gondouin; Romain Bénard; Marie Piazza; Ronald BUGGAGE; Francine F Behar-Cohen; Thierry Bordet
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 228. doi:
Cell Permeable Peptain for Neuroprotection in Glaucoma Open Access
Bindu Kodati; Vignesh Krishnamoorthy; Rooban B Nahomi; Mi-Hyun Nam; Renuka M Chaphalkar; Kallen J Beall; Ashley Kay Brodrick; Ram H Nagaraj; Raghu R Krishnamoorthy; Dorota Luiza Stankowska
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 229. doi:
Pharmacological chaperones for RHO-associated retinitis pigmentosa Open Access
Yuanyuan Chen; Bing Feng; Owen Clinger; Mark Schurdak; Yibo Xi
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 230. doi:
Evaluation of Cytotoxicity of Anti-VEGF Molecules on Vascular Endothelial Growth Factor Enriched Choroidal Vascular Endothelial Cells Open Access
Bharani Krishna Mynampati Arunadithya; Sandeep grover
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 231. doi:
Anti-Inflammatory and Protective Effects of Topical Ophthalmic (R)-DOI 0.01% in Allergic Conjunctivitis and Recurrent Intermediate Uveitis Disease Models in Rabbits. Open Access
EMELINE MAILLET; Daniel Skutnik; Jeffrey Adam Jamison; David Bailey; Marianna Bacellar-Galdino; David Garlick
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 232. doi:
Improvement of Visual Function following Multi-wavelength Photobiomodulation with the Valeda Light Delivery System on Electroretinography (ERG) and Best Corrected Visual Acuity (BCVA) in ... Open Access
clark tedford; Dan Montzka; Marion Ronit Munk; Scott Pollack; Maverick Perich; Tanya Perich; Stephanie Tedford; Cindy Croissant; Matt Emmer; Laurie Cox; Shannon Brumage; Rene Ruckert; Larry Perich
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 233. doi:
Spatiotemporal mapping of neurogenic gene expression during mammalian retinal development Open Access
Shabnam Majidi; Nathan Mundell; Jiyao Zhu; Rebecca Girresch; Nick Steinauer; Aurore Valfort; Suomia Abuirqeba; Amina Kamerić; Monideepa Sengupta; Grant Kolar; Judy M Ogilvie; Colin Flaveny
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 234. doi:
Multi-modal Geographic Atrophy Lesion Growth Rate Prediction using Deep Learning Open Access
Qi Yang; Neha Anegondi; Verena Steffen; Christina Rabe; Daniela Ferrara; Simon S. Gao
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 235. doi:
AI-based quantification of photoreceptor maintenance in the treatment of Geographic Atrophy Secondary to AMD in the FILLY trial Open Access
Ursula Schmidt-Erfurth; Julia Mai; Gregor Sebastian Reiter; Sophie Riedl; Dmitrii Lachinov; Wolf-Dieter Vogl; Hrvoje Bogunovic
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 236. doi:
Characterization of macular neovascularization in geographic atrophy Open Access
Riccardo Sacconi; Maria Brambati; Alexandra Miere; Eliana Costanzo; Vittorio Capuano; Enrico Borrelli; Marco Battista; Maria Cristina Parravano; Eric H Souied; Francesco Bandello; Giuseppe Querques
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 237. doi:
SD-OCT based analysis of treatment effects on Geographic Atrophy secondary to AMD in the FILLY trial of Pegcetacoplan Open Access
Julia Mai; Sophie Riedl; Gregor Sebastian Reiter; Dmitrii Lachinov; Wolf-Dieter Vogl; Hrvoje Bogunovic; Ursula Schmidt-Erfurth
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 238. doi:
Monitoring GA lesion size on OCT using automated deep learning-based image segmentation in the FILLY phase II clinical trial Open Access
Dmitrii Lachinov; Julia Mai; Gregor Sebastian Reiter; Sophie Riedl; Wolf-Dieter Vogl; Ursula Schmidt-Erfurth; Hrvoje Bogunovic
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 239. doi:
Border Location Affects Local Progression Kinetics of Geographic Atrophy Open Access
Lucian V Del Priore; Mengyuan Sun; Aneesha Ahluwalia; Benjamin Young; Michael Park; Liangbo Shen
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 240. doi:
Precursors to Geographic Atrophy in Age-Related Macular Degeneration (AMD) Open Access
Kenneth Taylor; Spencer Cleland; Jeong W Pak; Mark Banghart; Barbara Blodi; Amitha Domalpally
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 241. doi:
Aged mice with AMD-associated genetic mutations in complement or extracellular matrix do not exhibit slow dark adaptation Open Access
Shawn Hanks; Ivana Arellano; Erika Lima; Joanna Vrouvlianis; Yubin Qiu; Natasha M Buchanan; Siyuan Shen; Garrett Klokman; Maura Crowley; Chad Bigelow; Stephen Poor
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 242. doi:
Downregulation of TNFRSF10A promotes RPE cell death via PKC deactivation Open Access
Kenichiro Mori; Keijiro Ishikawa; Iori Wada; Yuki Kubo; Takahito Nakama; Masato Akiyama; Mitsuru Arima; Shoji Notomi; Yusuke Murakami; Toshio Hisatomi; Shintaro Nakao; Shigeo Yoshida; Koh-hei Sonoda
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 243. doi:
Ocular phenotype of RORgt promoter-driven AhR knockout mice in response to RPE injury Open Access
James Regun Karmoker; Sarah Bounds; Jacob Farriester; Kim Youngsil; Yan Chen; Jiyang Cai
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 244. doi:
A transcriptome based computational drug repurposing analysis to target the RPE/choroid abnormality in advanced age-related macular degeneration Open Access
Dhanach Dhirachaikulpanich; Luminita I Paraoan
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 245. doi:
Characterization of Phospholipid Transfer Protein (PLTP) and Cholesterol Ester Transfer Protein (CETP) expression and activity levels in human Retinal Pigment Epithelium (RPE) cells Open Access
Andrew Pivovar; Leina Ibrahim; Amirfarbod Yazdanyar
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 246. doi:
The close link between hypoxia and autoinduction of placental growth factor in galectin-1 expression in retinal pigment epithelium cells Open Access
Taku Yamamoto; Atsuhiro Kanda; Satoru Kase; Susumu Ishida
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 247. doi:
Downregulation of ABCA1 in iPSC-derived RPE cells impaired cholesterol efflux leading to intracellular lipid accumulation Open Access
Florian Peters; David Grubich Atac; Wolfgang Berger; Anneke I Den Hollander; Christian Grimm
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 248. doi:
Altered microRNA expression patterns in the murine retina with diabetic retinopathy following Intravitreal injection of human CD34+ stem cells Open Access
Zeljka Smit-McBride; Amirfarbod Yazdanyar; Whitney Cary; Jan Nolta; Susanna S Park
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 249. doi:
11-month-old Humanin-G in H2O High Resolution Mass Spectrometry Analysis Open Access
Mustafa Ozgul; Ben Katz; M. Cristina Kenney
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 250. doi:
Differences in gene expression and metabolism among AMD and non-AMD patients arise only after iPSC are differentiated into RPE Open Access
Huey Cai; Jie Gong; Lawrence J Rizzolo; Lucian V Del Priore; Mark Anthony Fields
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 251. doi:
Topical Ketotifen fumarate inhibits mast cell degranulation and loss of retinal pigment epithelial cells in rat model for geographic atrophy Open Access
Tomohiro Niizawa; Imran Ahmed Bhutto; Anupama Tiwari; Rhonda R. Grebe; Jesse Alt; Rana Rais; Malia Michelle Edwards; Gerard A Lutty
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 252. doi:
The ARMS2 insertion/deletion leads to systemic upregulation of secreted HTRA1 levels in the blood in AMD patients Open Access
Yang Pan; Akiko Suga; Toru Noda; Inderjeet Kaur; Taraprasad Das; Subhabrata Chakrabarti; Robyn H Guymer; Margaret M DeAngelis; Paul N Baird; Takeshi Iwata
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 253. doi:
Complexation of A2E with a model protein increases photoreactivity of the bis-retinoid in selected model systems Open Access
Justyna Anna Furso; Andrzej Zadlo; Grzegorz Szewczyk; Tadeusz Sarna
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 254. doi:
Increased Reactive Oxygen Species (ROS) production in Patient-specific iPSC-derived RPE from AMD patients Open Access
Jie Gong; Huey Cai; Lucian V Del Priore; Mark Anthony Fields
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 255. doi:
Chronic Oxidative Stress in Primary Retinal Pigmented Epithelium Monolayers Increases Basolateral Exosome Release and Changes Both Exosome and Extracellular Matrix Proteomes Open Access
Belinda Hernandez; Mikael Klingeborn; Nikolai Skiba; Daniel Grigsby; Una Kelly; Martha Caday; Arvydas Maminishkis; TeddiJo Watkins; Sheldon S Miller; W. Daniel Stamer; Catherine Bowes Rickman
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 256. doi:
Comprehensive Analysis of Genetic Variants of Uncertain Significance in Complement Factor I (CFI) in Advanced Age Related Macular Degeneration (AAMD) Open Access
Anuja Java; Rafael Widjajahakim; John Atkinson; Johanna M Seddon
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 257. doi:
p53 plays a regulatory role in DNA damage response of mono- and multi-nucleated retinal pigment epithelial cells Open Access
qin ke; Lili Gong; Ming Zou; Ruili Qi; David W Li
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 258. doi:
The role of the EPCR pathway in protecting endogenous repair cells in the choriocapillaris Open Access
Elisa Peixoto; Sarah Chambers; Stuart McKeown; Lynsey-Dawn Allen; Pietro Bertelli; Reinhold J. Medina; Alan Stitt
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 259. doi:
Phagocytic function is reduced in the mouse retinal pigmented epithelium with age Open Access
Jessica Yuen Wuen Ma; Ursula Greferath; Linda Fothergill; KA Vessey; Josephine Hiao Ching Wong; EL Fletcher
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 260. doi:
Regulation of inner blood retina barrier integrity induces a geographic atrophy-like phenotype in animal models Open Access
Natalie Hudson; Ema Ozaki; Avril Reddy; Kieva Byrne; Sarah Doyle; Matthew Campbell
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 261. doi:
Identification of fluorophores from human retina by TLC coupled MALDI and LC-MS/MS analysis Open Access
Ankita Kotnala; David M.G. Anderson; Jarod A. Fincher; Jeffrey Messinger; Christine A Curcio; Kevin L. Schey
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 262. doi:
TREM2+ choroidal macrophages regulate vascular and lipid homeostasis in the choroid and are lost in age-related macular degeneration (AMD) Open Access
Seth Fortmann; Robert Rosencrans; Yvonne Adu-Agyeiwaah; Haley Patton; Maria B Grant
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 263. doi:
MODELING ACCELERATED RETINAL AGING USING A DOMINANT MUTANT OF THE DNA POLYMERASE GAMMA SUB-UNIT 1 Open Access
Cristhian J Ildefonso; Erin Walsh; Raela Brianne Ridley; Ahmed Jafri; Alfred S Lewin
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 264. doi:
Inflammatory adipose activates nutritional immunity leading to retinal dysfunction Open Access
Jacob Sterling; Bailey Baumann; Sierra Foshe; Andrew P Voigt; Samyuktha Guttha; Ahab Alnemri; Sam McCright; Venkata R M Chavali; David Hill; Deborah A Ferrington; Dwight Stambolian; Robert F Mullins; David Merrick; Joshua L Dunaief
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 265. doi:
Effects of Spectrum of Wavelengths of Blue-Light on Retinal Pigment Epithelial Cells Open Access
Mohamed Abdouh; Alicia Alejandra Goyeneche; Emma Youhnovska; Raphaelle Denis; Paulina Garcia de Alba Graue; Julia Valdemarin Burnier; Miguel N Burnier
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 266. doi:
Unbiased omics analyses of the sigma-2 antagonist CT1812 in age-related diseases and models Open Access
Lora Waybright; Courtney Rehak; Emily Watto; Anthony Caggiano; Mary E Hamby
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 267. doi:
Detailed phenotypic investigation of HtrA1 transgenic mice model Open Access
Waseem Ahamed Shihabuddeen; Yasuo Yanagi; Richard Yu Ming Chuan; Veluchamy A Barathi; Xiaomeng Wang; Gemmy Chui Ming Cheung
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 268. doi:
MeCP2-mediated mitochondrial impairment evidenced in Stargardt disease Open Access
Arpita R. Dave; Eunice Sze Yin Ng; Zhichun Jiang; Jane G Hu; Michael B Gorin; Anna Matynia; Linsey Stiles; Roxana A Radu
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 269. doi:
Histological Correlation of Basement Membrane Deposits in Age-Related Macular Degeneration and Renal Dense Deposit Disease Open Access
Lauren Malaya; Marjan Afrouzian; Praveena Gupta
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 270. doi:
Growth of geographic atrophy in non-neovascular age-related macular degeneration measured using sub-RPE illumination on optical coherence tomography Open Access
Phuoc-Hanh Le; Sumit Sharma; Amy Babiuch; Peter K Kaiser; Kimberly Baynes; Cindy Chen; Michael Ramos; Kayvan Barekatain; Megan Ann McDonald; Danielle Burton; Justis P Ehlers; Sunil K. Srivastava
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 271. doi:
Ten year outcome of neovascular age-related macular degeneration: association of functional and anatomical treatment outcomes with major risk allele for the disease Open Access
Brice Nguedia Vofo; Gala Beykin; Jaime Levy; Itay Chowers
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 272. doi:
Ceria-coated melanin as a novel antioxidant for age-related macular degeneration Open Access
Yongsu Kwon; Min Zheng; Zongchao Han
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 273. doi:
VEGF-A/Ang-2 neutralization causes sustained prevention of subretinal macrophage infiltration in a mouse model of spontaneous choroidal neovascularization Open Access
Jérémie Canonica; Sabine Uhles; Richard Foxton; Nadine Cole; Mirjana Lazendic; Marina Garcia Garrido; Peter Westenskow
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 274. doi:
Association of oral montelukast with reduced odds of developing neovascular age-related macular degeneration Open Access
Irmak Karaca; Wataru Matsumiya; Amir Akhavanrezayat; Gunay Uludag; Cigdem Yasar; Azadeh Mobasserian; Jaclyn Joyce Hwang; Sherin Lajevardi; Brandon Chau Lam; Rubbia Afridi; Diana V Do; Yasir J Sepah; Quan Dong Nguyen
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 275. doi:
Inter-reader repeatability of structural biomarkers in age-related macular degeneration in the multi-center MACUSTAR study Open Access
Marlene Sassmannshausen; Maximilian Pfau; Sarah Thiele; Charlotte Behning; Matthias Schmid; Frank G Holz; Steffen Schmitz-Valckenberg
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 276. doi:
Treatment Efficacy of Dual Release of Aflibercept and Dexamethasone from a Single Hydrogel Drug Delivery System in a Laser-induced Choroidal Neovascularization Model Open Access
Kayla Rudeen; Wenqiang Liu; Katherine L. Lydon; Sabrina J.K. Derwent; William F Mieler; Jennifer J Kang-Mieler
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 277. doi:
A Phase 1b Multi-Center, Open Label, Single-Arm Safety Study of Intravitreal Pegcetacoplan Supporting the Phase 3 DERBY and OAKS Studies for Geographic Atrophy: A Solution to “Tarmac Dela... Open Access
Nathan Steinle; jeffrey heier; Rishi P Singh; David S Boyer; Eleonora M Lad; Ravi Metlapally; Ramiro Ribiero; Charles Clifton Wykoff; Chris Holmes
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 278. doi:
Area under the Curve as an Alternative Outcome Measure of Dark Adaptation Response Open Access
Shrinivas Pundlik; Archana Nigalye; Ines Lains; Kevin Mendez; Raviv Katz; Janice Kim; Vivian P Douglas; Anna Marmalidou; Ivana K Kim; John Miller; Demetrios G. Vavvas; Joan W Miller; Deeba Husain; Gang Luo
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 279. doi:
Uniocular peripheral retinal laser stabilizes AMD visual outcomes binocularly Open Access
Danny H.- Kauffmann Jokl; R Theodore Smith; Rando Allikmets; Sankha Amarakoon; weijia fan; mihai busuioc; Suzanne Yzer; jan van meurs
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 280. doi:
Saccade Latencies are Longer for Early/Intermediate AMD than Age-Matched Normal Patients. Open Access
William H Ridder; Lani May Centeno
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 281. doi:
Plasma rich in growth factors protects retina against blue light in an in vivo model. Open Access
Susana del Olmo Aguado; Carlota Suárez-Barrio; Eva García-Pérez; Enol Artime; Jesus Merayo-Lloves
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 282. doi:
AMD Drusenoid deposits “L”, Lipid type: Density, Structural,Volume analysis, and their evolution study with Morphology-Structural software.5 years follow-up Open Access
Corinne Gonzalez
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 283. doi:
Impact of Baseline Macular Atrophy on Long-Term Outcomes in Neovascular Age-Related Macular Degeneration Patients Treated with anti-VEGF Treatment Open Access
Mark Quoc-Tin Bui; Grant L Hom; Amogh Iyer; Aneesha Kalur; Justin Muste; Thais F. Conti; Rishi P Singh; Katherine Talcott
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 284. doi:
Fear associated with COVID-19 in neovascular age-related macular degeneration patients Open Access
Jean-Philippe Rozon; Mélanie Hébert; Serge Bourgault; Mathieu Caissie; Laurence Letartre; Eric Tourville; Ali Dirani
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 285. doi:
A Retrospective Study on the Use of Brolucizumab for the Treatment of NVAMD: A 1-Year Private Practice Experience Open Access
Samara J Hamou; Christian D Raimondo; Pamela Weber; Bonnie C Woods
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 286. doi:
Comparison of real-life treatment of naïve patients with ranibizumab over 24 months for neovascular AMD, diabetic macular edema, retinal vein occlusion and myopic CNV – results of the cur... Open Access
Ramin Khoramnia; Christos Haritoglou; Kristina Markova; Matthias Iwersen; Ulrike Michel; Salvatore Grisanti; Thomas Hammer; Jens Schrecker; Christoph Winkler von Mohrenfels; Focke Ziemssen
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 287. doi:
Wall-to-Lumen Ratio is altered in Intermediate Age-Related Macular Degeneration but not exacerbated with Hypertension. Open Access
Lisa Nivison-Smith; Matt Trinh; Alvia Faiza; Tithi Roy
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 288. doi:
Progression of macular atrophy in patients receiving long-term anti-VEGF therapy for age-related macular degeneration; Real Life Data Open Access
Blazaki Styliani; Emmanouil Blavakis; Georgios Smoustopoulos; Georgios Bontzos; Anastassios Stavrakakis; Gregory Chlouverakis; Stamatina Kabanarou; Tina Xirou; Miltiadis K Tsilimbaris
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 289. doi:
The Effect of Treatment Delay on Exudative Age-Related Macular Degeneration Patients Due to the COVID-19 Pandemic Open Access
Arko Ghosh; Tyler Blahnik; David Fleischman; Alice Yang Zhang
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 290. doi:
Using the What-if Tool to perform nearest counterfactual analysis on an AutoML model that predicts visual acuity outcomes in patients receiving treatment for wet age-related macular degen... Open Access
Abdallah Abbas; Sara Beqiri; Siegfried Wagner; Edward Korot; Ritvij Singh; Robbert Struyven; Pearse Keane
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 291. doi:
Clinical validation of Age-Related Macular Degeneration remote monitoring device Open Access
Angela Yim; Lyna Azzouz; Andrew Yu; Yannis M Paulus
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 292. doi:
Elucidating the role of inner blood retina barrier integrity in the development of dry AMD Open Access
Deirdre Harford; Natalie Hudson; Aisling Naylor; Jeffrey O'Callaghan; Alan Hopkins; Sarah Doyle; Matthew Campbell; Mark Cahill
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 293. doi:
Reduction of choroidal thickness was not associated with the outcomes of photodynamic therapy for pachychoroid spectrum diseases Open Access
norihiko misawa; akika kyo; kumiko hirayama; Manabu Yamamoto; michiko hirabayashi; Takeya Kohno; shigeru honda
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 294. doi:
Improved sensitivity of microperimetric outcomes for clinical studies in age-related macular degeneration Open Access
Yaniv Barkana; Susanne Gunda Pondorfer; Steffen Schmitz-Valckenberg; Hermann Russ; Robert Finger
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 295. doi:
Comparison of depressive symptoms between age-related macular degeneration and glaucoma patients who live in a developing country. Open Access
Kenzo S Tomishige; Caroline Schiave Germano; Patrícia Asperti Ottaiano; Renato Maia Maccione; Niro Kasahara
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 296. doi:
Characterization of retinal structural and vascular pathologies in Royal College of Surgeons rat using visible-light OCT Open Access
Shaohua Pi; Bingjie Wang; Renee Christine Ryals; Yali Jia
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 297. doi:
Longitudinal Follow-up of Vascularized Drusen Open Access
Koosha Ramezani; Omar Abu-Qamar; Jeffrey Heier; David S Boyer; David M Brown; Sumit P Shah; Charles Clifton Wykoff; Sabin Dang; Namrata Saroj; Nadia K Waheed
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 298. doi:
ROLE OF INFLAMMATION MARKERS AND EFFECTS OF HUMANIN G IN AMD Open Access
Sonali R Nashine; M. Cristina Kenney
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 299. doi:
The Impact of the COVID-19 Pandemic on Intravitreal Bevacizumab Use Open Access
Ashton Perlroth; Kapil Mishra; Diana V Do
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 300. doi:
Histology and clinical lifecycle of acquired vitelliform lesion, a pathway to atrophy in age-related macular degeneration Open Access
Max Philipp Brinkmann; Tommaso Bacci; Jeffrey Messinger; Deepayan Kar; Kenneth R Sloan; Ling Chen; Timothy Hamann; Maximilian Wiest; K Bailey Freund; Sandrine Anne Zweifel; Christine A Curcio
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 301. doi:
MACUSTAR cross-sectional data: Repeatability and discriminatory power of visual function tests Open Access
Hannah M P Dunbar; Charlotte Behning; Deanna J Taylor; Bethany Elora Higgins; Giovanni Montesano; Alison Binns; Jan Henrik Terheyden; Amina Abdirahman; Nadia Zakaria; Stephen Poor; Gary S Rubin; Matthias Schmid; David P. Crabb; Ulrich F O Luhmann
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 302. doi:
Corneal laser procedure for vision improvement in patients with late stage age-related macular degeneration and other retinal disorders Open Access
Michael Berry; Robert Devenyi; Samuel Markowitz; Michael Berry II
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 303. doi:
Inhibition of EB3 prevents choroidal neovascularization in AMD model of non-human primates Open Access
Quinn Lee; Xinyan Qu; Martin Sanders; Mark Rosenblatt; Asrar B Malik; Yulia Komarova
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 304. doi:
Location-specific patterns of inner retinal thinning in intermediate Age-related Macular Degeneration Open Access
Matt Trinh; Michael Kalloniatis; Lisa Nivison-Smith
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 305. doi:
M-CHARTS evaluation and comparison of two Aflibercept regimens for neovascular age-related macular degeneration Open Access
Marion Schroeder; Monica K Loevestam-Adrian
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 306. doi:
Comparison of the illness perception between age-related macular degeneration and glaucoma patients living in a middle-income country Open Access
Caroline Schiave Germano; Patrícia Asperti Ottaiano; Renato Maia Maccione; Kenzo S Tomishige; Niro Kasahara
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 307. doi:
Predictive model for incomplete and complete retinal pigment epithelium and outer retinal atrophy in non-exudative age related macular degeneration Open Access
Sohani Amarasekera; Anindya Samanta; Mahima Jhingan; Supriya Arora; Sumit R Singh; Davide Tucci; Joseph N Martel; Jose Alain Sahel; Thomas R Friberg; Alexander J Anetakis; Denise Gallagher; Andrew W Eller; Carlo Cagini; Marco Lupidi; Jay Chhablani
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 308. doi:
MiRNA-24 represses TGF-β2 induced epithelial-mesenchymal transition (EMT) and fibrosis in RPE cells Open Access
Yinga Wu; Katherine Brynn; Jing Ma; Shusheng Wang
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 309. doi:
Genetic characterization of a Portuguese age-related macular degeneration population Open Access
Patrícia Barreto; Claudia Farinha; Rita Coimbra; Maria Luz Cachulo; Joana Barbosa Melo; Isabel Marques Carreira; Maria Helena Madeira; Carel Hoyng; Anneke I Den Hollander; Jose G Cunha-Vaz; Rufino Silva
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 310. doi:
COVID-19 pandemic lockdown international impact on nAMD, DME and RVO intravitreal therapy outcomes: Fight Retinal Blindness International registry Open Access
Javier Zarranz-Ventura; Vuong Nguyen; Catherine P Creuzot Garcher; Frank D Verbraak; Louise OToole; Alessandro Invernizzi; Francesco Viola; David Squirrell; Daniel Barthelmes; Mark C Gillies
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 311. doi:
[Retracted] Short-Term Normobaric Hyperoxia Treatment for Dry Age-Related Macular Degeneration: An Exploratory Study Open Access
Justin Wang; Colin Lemire; Brendan Seto; Keiko Yamada; Jorge G Arroyo
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 312. doi:
Correlations Between AMD Severity and OCT Thickness Open Access
Peyton Grisso; Jeong W Pak; Tharindu De Silva; Henry Wiley; Tiarnan D L Keenan; Elvira Agron; Emily Y Chew; Catherine A Cukras
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 313. doi:
EXPOSURE TO ENRICHED ENVIRONMENT PROTECTS THE CENTRAL RETINAL PIGMENT EPITHELIUM AND RETINA ON A DRY-AMD EXPERIMENTAL MODEL IN MICE. Open Access
Hernan Dieguez; Horacio Eduardo Romeo; Agustina Alaimo; Maria Florencia Gonzalez Fleitas; Pablo Horacio Sande; Ruth Rosenstein; Damian Dorfman
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 314. doi:
ARMS2 and CFH polymorphism and aqueous humor complement activation products in Japanese patients with age-related choroidal neovascularization Open Access
Tetsuju Sekiryu; Yutaka Kato; Keiichiro Tanaka; Yasuharu Oguchi; Tomoko Omori; Yumi Ishida; Takeshi Machida; Hideharu Sekine; Kanako Itagaki; Ogasawara Masashi
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 315. doi:
Diagnostic power of rapid ETDRS-grid matched objective perimetry in early- to late-stage AMD Open Access
Ted Maddess; Bhim Bahadur Rai; Corinne Carle; Emilie Rohan; Joshua van Kleef; Rohan W Essex; Faran Sabeti
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 316. doi:
Per-region visual field sensitivities and delays in AMD Open Access
Bhim Bahadur Rai; Rohan W Essex; Faran Sabeti; Ted Maddess; Emilie Rohan; Josh P van Kleef; Corinne Carle
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 317. doi:
Blue Color Contrast Test in non-advanced age-related macular degeneration Open Access
John David Rodriguez; Matthew Chapin; Garrick Wallstrom; Mark B Abelson
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 318. doi:
Longitudinal evaluation of variable contrast flicker test in non-advanced age-related macular degeneration Open Access
Divya Narayanan; John David Rodriguez; Garrick Wallstrom; Mark B Abelson
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 319. doi:
Vanishing optotype reading test in non-advanced age-related macular degeneration Open Access
Donna Welch; John David Rodriguez; Divya Narayanan; Mark B Abelson
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 320. doi:
Long-term safety and efficacy of ISTH0036 – a selective TGF-β2 blocking antisense oligonucleotide in preclinical and Phase 1 clinical studies. Open Access
Rene Ruckert; Marion Ronit Munk; Katja Wosikowski; Michel Janicot
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 321. doi:
Elucidating Mouse Models of Retinal Disease Using Systems Genetics and the BXD Family of Mice Open Access
TJ Hollingsworth; Anand Swaroop; Emily Y Chew; David Ashbrook; William White; Robert Williams; Monica M Jablonski
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 322. doi:
Stride length in different luminance in non-advanced age-related macular degeneration Open Access
Kara Quealy; Ethan Bensinger; Kelly Theberge; Mark B Abelson
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 323. doi:
Delineating temporal and spatial recruitment of systemically administered RPE65-programmed bone marrow-derived cells to the retina in a mouse model of age-related macular degeneration Open Access
Carolina Rovarotto; Juliana Godoy; Xiaoping Qi; Michael E Boulton
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 324. doi:
Prediction of AMD Progression Within Eye-Specific Baseline Severity Scales, and Attributable Fraction for Modifiable Factors and a Genetic Risk Score Open Access
Rafael Widjajahakim; Bernard Rosner; Johanna M Seddon
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 325. doi:
Tranilast protects against endoplasmic reticulum stress-induced cell death in retinal pigment epithelial cells: Implications for age-related retinal diseases Open Access
Thangal Yumnamcha; Michael Guerra; Ebrahim Abdul-Shukkur; Elizabeth A Berger; Lalit S Pukhrambam; Ahmed S Ibrahim
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 326. doi:
Remote monitoring device for tracking the progression of Age-Related Macular Degeneration: Device and hardware validation Open Access
Lyna Azzouz; Angela Yim; Andrew Yu; Yannis Mantas Paulus
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 327. doi:
Contrast Sensitivity Function in Non-Neovascular Age-related Macular Degeneration Measured with Active Learning Open Access
Filippos Vingopoulos; Neal Patel; Raviv Katz; Itika Garg; Edward S Lu; Ines Lains; Megan Kasetty; Rebecca Silverman; Archana Nigalye; Luis Andres Lesmes; Ivana K Kim; Leo A Kim; Deeba Husain; Joan W Miller; Demetrios G. Vavvas; John Brown Miller
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 328. doi:
Platelet complement activity reveals a new target for AMD treatment Open Access
Nicholas Pfahler; Indre Bielskus; Agni Kakouri; Michael Giovingo; Nicholas J Volpe; Paul A Knepper
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 329. doi:
Can drusen growth in age-related macular degeneration be slowed by oral curcumin? Open Access
Indre Bielskus; Nicholas Pfahler; Agni Kakouri; Stephanie Aman; Zibute Zaparackas; Paul A Knepper
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 330. doi:
An evaluation of the use of 3-hydroxy-3-methyl-glutaryl-coenzyme A reductase inhibitors (statins) and progression of age-related macular degeneration Open Access
Erica Smith; Clayton Kirk; Suzanne Kirk; Ping Bu; Evan B Stubbs; Felipe de Alba
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 331. doi:
Slowing the progression of geographic atrophy with oral resveratrol, quercetin, and curcumin Open Access
Agni Kakouri; Nicholas Pfahler; Indre Bielskus; Michael Giovingo; Stephanie Aman; Zibute Zaparackas; Paul A Knepper
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 332. doi:
Avacincaptad Pegol, A Novel C5 Inhibitor, Demonstrates a Continued Reduction in the Mean Rate of Geographic Atrophy Growth: 18-Month Results from the GATHER1 Clinical Trial Open Access
Veeral Sheth
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 333. doi:
Persistent Subretinal Fluid in the Comparison of Age-Related Macular Degeneration Treatments Trials (CATT) Open Access
Jason Quan College; Maxwell Pistilli; Ebenezer Daniel; Maureen G Maguire; Gui-Shuang Ying
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 334. doi:
Impact of Duration of Exposure to Residual Intraretinal Fluid on Visual Function Outcomes in Neovascular Age-Related Macular Degeneration Open Access
Rishi P Singh
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 335. doi:
Dark Adaptation Survey as a Screening Tool for Age Related Macular Degeneration Open Access
Noreen Shaikh; Mahesh Bhardwaj; Amer Mosa Alwreikat; Sidrah Anjum; Dan Hagan; Shane Bowen; David Ramsey
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 336. doi:
The impact of early central macular total retinal fluid index instability on future exudative volatility in neovascular AMD Open Access
Thuy K Le; Leina Lunasco; Robert Zahid; Ming Hu; Jamie Reese; Sunil K. Srivastava; Justis P Ehlers
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 337. doi:
Effect of subretinal fluid (SRF) resolution on visual acuity in patients with neovascular age-related macular degeneration (nAMD) Open Access
David Ryan Lally; Lauren Hill; Min Tsuboi
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 338. doi:
Relationship of Retinal Vessel Diameters with Age-Related Macular Degeneration Open Access
Sara Toulouie; Glenn Yiu; Julia Pan; Sean Chang; Kiersten Snyder
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 339. doi:
The RAP study, Report 4: Discoloration of the macular region in patients with macular neovascularization type 3 Open Access
Bilal Haj Najeeb; Gabor Deak; Ursula Schmidt-Erfurth; Bianca S Gerendas
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 340. doi:
Association between visual acuity and intraretinal (IRF) or subretinal (SRF) fluid in patients with neovascular age-related macular degeneration (nAMD) treated with intravitreal afliberce... Open Access
Varun Chaudhary; Frank G Holz; Philip Hykin; Edoardo Midena; Eric H Souied; Sebastian Wolf; Tobias Machewitz; George Lambrou; Paul Mitchell
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 341. doi:
AAO IRIS Registry data replicates VIEW 1 and VIEW 2 clinical trial outcome data Open Access
Theodore Leng; Jason Xu; Ashley Kras; Kevin Wood; Rahul Doriswami; Chhaya Shadra; Aracelis Torres; Charles Li; Flora Lum
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 342. doi:
Association of Human Plasma Metabolomics with Delayed Dark Adaptation in Age-Related Macular Degeneration Open Access
Janice Kim; Kevin Mendez; Ines Lains; Archana Nigalye; Raviv Katz; Shrinivas Pundlik; Ivana K Kim; Liming Liang; Demetrios G. Vavvas; John Miller; Joan W Miller; Jessica A Lasky Su; Deeba Husain
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 343. doi:
Are we doing better? Impact of treatment paradigm change on neovascular age-related macular degeneration treatment outcomes over the past decade. A big data analysis. Open Access
Roy Schwartz; Alasdair Warwick; Abraham Olvera-Barrios; Maria Pikoula; Aaron Y Lee; Spiros Denaxas; Paul Taylor; Catherine Egan; Usha Chakravarthy; Peck Lin Lip; Adnan Tufail
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 344. doi:
Plasma Metabolomic Profiles Associated with Three-Year Progression of Age-related Macular Degeneration Open Access
Ines Lains; Archana Nigalye; Kevin Mendez; Raviv Katz; Vivian P Douglas; Rachel S Kelly; Ivana K Kim; John Miller; Demetrios G. Vavvas; Jessica A Lasky Su; Joan W Miller; Deeba Husain
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 345. doi:
Dietary Nitrate Consumption And Risk of Progression in Age-Related Macular Degeneration Open Access
Geoffrey Kenneth Broadhead; Elvira Agron; David Peprah; Tiarnan D L Keenan; Traci E Clemons; Tom Lawler; Julie A Mares; Emily Y Chew
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 346. doi:
Supplement intake and plasma nutritional biomarkers reduce risk for second eye progression in age-related macular degeneration. Open Access
Yara T E Lechanteur; Thomas J Heesterbeek; Anneke I Den Hollander; Laura Lores de Motta; Ilhan E Acar; Eiko K de Jong; B. Jeroen Klevering; Caroline C. W. Klaver; Carel Hoyng
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 347. doi:
Ophthalmic Properties of Targeted Fusogenic Nanoparticles as Therapeutic Carriers Open Access
William R Freeman; Joel F Grondek; Melina Cavichini; Alexandra Warter; Ruhan Fan; Kristyn Huffman; Michael J Sailor
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 348. doi:
Simultaneous Ang-2/VEGF-A inhibition prevents subretinal fibrosis progression in preclinical mouse models of choroidal neovascularization (CNV) Open Access
Markus Linder; Richard Foxton; Sabine Uhles; Franco Revelant; Mirjana Lazendic; Jérémie Canonica; Marina Garcia Garrido; Peter Westenskow
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 349. doi:
Pharmacokinetic profile of the Port Delivery System with ranibizumab (PDS) in the phase 3 Archway trial Open Access
Peter A Campochiaro; Shamika Gune; Mauricio Maia; Han Ting Ding; Katie Maass
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 350. doi:
Artificial intelligence algorithm for retinal fluid volume quantification from self-imaging with a Home OCT System Open Access
Anat Loewenstein; Dafna Goldberg; Dinah Zur; Shiri Shulman; Tiarnan D L Keenan; Michaella Goldstein
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 351. doi:
Phase 1 Study of Intravitreal Gene Therapy with ADVM-022 for neovascular AMD (OPTIC Trial) Open Access
Brandon Busbee; David S Boyer; Arshad M. Khanani; Charles Clifton Wykoff; Dante Joseph Pieramici; Carl Regillo; Carl J Danzig; Brian C Joondeph; James Major; Carol Hoang; Adam Turpcu; Carol Chung; Szilard Kiss; Mehdi Gasmi; Aaron Osborne
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 352. doi:
5-Year Results of a Home Monitoring Device in Study Participants at High Risk for Neovascular Age-related Macular Degeneration Open Access
Marcus T Altman; Merina Thomas; Voraporn Chaikitmongkol; Neil M Bressler
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 353. doi:
Comparison of retinal characteristics in two rabbit strains Open Access
Randolph D Glickman; Igor Nasonkin
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 354. doi:
Identification of cis-regulatory elements that allow for AAV-based Müller glial-specific labeling and manipulation in the retina Open Access
Cheng-Hui Lin; Candace Chan; Man-Ru Wu; Alexander Davis; Sui Wang
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 355. doi:
Retinal Vascular Physiology Biomarkers in a 5XFAD Mouse Model of Alzheimer’s Disease Open Access
Nathanael Matei; Sophie Leahy; Norman P Blair; James Burford; Mahnaz Shahidi
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 356. doi:
Retrobulbar blood flow in rat eyes in acute ocular hypertension Open Access
Ronald H Silverman; Raksha Urs; Gulgun Tezel; Xiangjun Yang; Inez Nelson; Jeffrey A Ketterling
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 357. doi:
Retinal Hypoxia Evaluation Using Organic Room-Temperature Phosphorescent Nanoparticles Open Access
Yannis Mantas Paulus; Yingying Zeng; Van Phuc Nguyen; Yanxiu Li; Jinsang Kim
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 358. doi:
Impact of laser-induced damage on the fluorescence lifetimes at the rabbit fundus Open Access
Svenja Rebecca Sonntag; Eric Seifert; Maximilian Hamann; Britta Lewke; Dirk Theisen-Kunde; Ralf Brinkmann; Salvatore Grisanti; Yoko Miura
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 359. doi:
Mitochondrial elongation in retinal vascular cells as a result of exposure to high-glucose conditions Open Access
Ben Brenner; Yang Zhang; Junhun Kweon; Yong-Seok Song; Christine M Sorenson; Nader Sheibani; Hao Zhang
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 360. doi:
Quantitative and Qualitative Analysis of Retinal Hypoxia in a Mouse Model of Retinal Artery Occlusion (RAO) Open Access
MD Imam Uddin; Sara Jamal; Gary W. McCollum; John S Penn
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 361. doi:
Comprehensive retinal safety evaluation of photoacoustic microscopy in rabbits Open Access
Yanxiu Li; Wei Zhang; Van Phuc Nguyen; Naheed Wali Khan; Xiaobo Xia; Xueding Wang; Yannis M Paulus
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 362. doi:
Optically-triggered oxidative stress in mouse RPE as a model of geographic atrophy in AMD Open Access
Brian Quang Dang; Iris Mollhoff; Eric V. Tieu; Sook Hyun Chung; Ratheesh Kumar Meleppat; Pengfei Zhang; Robert J Zawadzki; Glenn Yiu
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 363. doi:
Comparative retinal imaging in mouse models of proteinopathies identifies disease-specific biomarkers Open Access
Lies De Groef; Lien Veys; Marjan Vandenabeele; Xavier Hadoux; Sophie Lemmens; Lutgarde Serneels; Jan Theunis; Bart De Strooper; Ingeborg Stalmans; Peter van Wijngaarden; Lieve K M Moons
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 364. doi:
Fluorescence Lifetime Imaging Ophthalmoscopy of mouse models of age-related macular degeneration Open Access
Yoko Miura; Britta Lewke; Erdal Tan Ishizuka; Svenja Rebecca Sonntag; Eric Seifert; Salvatore Grisanti; Ralf Brinkmann
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 365. doi:
Multimodal photoacoustic microscopy and OCT molecular imaging of choroidal neovascularization in rabbits using indocyanine green Open Access
Katherine Derouin; Van Phuc Nguyen; Yanxiu Li; Jessica Henry; Wei Zhang; Xueding Wang; Yannis Mantas Paulus
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 366. doi:
Multi-scale imaging of mouse corneas using optical coherence tomography and single-molecule localization microscopy Open Access
Yang Zhang; Zhen Cai; Lisa Beckmann; Cheng Sun; Hao Zhang
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 367. doi:
Retinal thickness changes over time by SD-OCT in a AD mouse model (APPNL-F/NL-F) Open Access
Rosa de Hoz; Elena Salobrar-García; Inés López Cuenca; Lídia Sanchez-Puebla; Jose A. Fernández-Albarral; Pilar Rojas; Juan J. Salazar; Ana Ramirez; Isabel Bravo-Ferrer; Violeta Medina; Maria A. Moro; Takaomi C. Saido; Takashi Saito; Jose Ramirez
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 368. doi:
Gold nanorod in vivo molecular imaging of choroidal neovascularization using OCT and photoacoustic microscopy in rabbits Open Access
Jessica Henry; Van Phuc Nguyen; Yanxiu Li; Wei Zhang; Xueding Wang; Yannis Mantas Paulus
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 369. doi:
A non-invasive imaging method to detect retinal hypoxia in a rat model of 50/10 oxygen-induced retinopathy using HYPOX4 Open Access
Sara Jamal; John Penn; MD Imam Uddin
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 370. doi:
Introduction of a novel animal model of subretinal fibrosis after choroidal neovascularization Open Access
Souska Zandi; Keijiro Ishikawa; Iori Wada; Shintaro Nakao; Laura Jahnke; Yuebing Li; Volker Enzmann; Martin Sebastian Zinkernagel
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 371. doi:
Large area choroidal and retinal vasculature maps in rats Open Access
Mircea Mujat; Ankit Patel; R. Daniel Ferguson; Nicusor Iftimia
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 372. doi:
Imaging murine corneal nerves in vivo using genetically-encoded calcium indicators Open Access
Matthew McPheeters; Brecken Blackburn; William J. Dupps; Andrew M Rollins; Michael W Jenkins
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 373. doi:
In Vivo Neural Imaging: The Impact of Retinal Neuropathy on Axonal Transport Open Access
Lucia Le Roux
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 374. doi:
Measurement of spatial and temporal retinal perfusion heterogeneity using OCTA Open Access
Arman Athwal; Dao-Yi Yu; Paula Yu; Zaid Mammo; Chandrakumar Balaratnasingham; Andrew Mehnert; Stephen Cringle; Marinko V Sarunic; Myeong Jin Ju
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 375. doi:
Retinal Nerve Fiber Layer Thickness in Normal Rhesus Macques and in Animals with a Polymorphism in OPA1 Open Access
Ala Moshiri; Tracy Nguyen; Rui Chen; Tim Stout; Jeffrey Rogers; Sara M Thomasy
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 376. doi:
Multicolor confocal fluorescence microscopy provides the enhanced visualization and fluorescent emission properties of intrinsic fluorophores in retinal pigment epithelium cells Open Access
Ratheesh Kumar Meleppat; Kaitryn Ronning; Sarah J Karlen; Karuna Kesavan Kothandath; Marie Burns; Edward N Pugh; Robert J Zawadzki
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 377. doi:
Optical Coherence Tomography Angiography (OCTA) caracterization of the choriocapillaris in a laser pig model of retinal degeneration Open Access
Francesca BARONE; Rishabh Gupta; Ruchi Sharma; Juan Amaral; Irina Bunea; Arvydas Maminishkis; Joe Phillips; David Gamm; Kapil Bharti
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 378. doi:
Clinical Observation of Allergic Conjunctival Diseases with Portable and Recordable Slit-Lump Device Open Access
HIROYUKI YAZU; Eisuke Shimizu; Shinri Sato; Naohiko Aketa; Taiichiro Katayama; Kazumi Fukagawa; Yoko Ogawa; Kazuo Tsubota; Hiroshi Fujishima
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 379. doi:
Comparing Refractive Accuracy of Cataract Surgery Using Multiple Keratometric Platforms Open Access
Kamran Ahmed; Su Naing; Paul Dickinson
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 380. doi:
Imaging the zonules using OCT with folded obliquely-aligned optics Open Access
Jonathan Bumstead; Sophie Kubach; Amanda Carpenter; Thomas Callan; Kabir Arianta; Yingjian Wang; Simon Bello; Si Xi Tom Zhao
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 381. doi:
Semantic segmentation of gonioscopic images exploiting adaptive ROI localization and uncertainty estimation Open Access
Andrea Peroni; Mauro Campigotto; Anna Paviotti; Emanuele Trucco
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 382. doi:
The association between the ocular discomfort and corneal dendritic cell densities Open Access
Azadeh Tavakoli; Maria Markoulli; Judith Flanagan; Eric B Papas
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 383. doi:
Assessment of Oblique Penlight Exam to Estimate Anterior Chamber Depth Open Access
John A Garcia; Amy Chomsky
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 384. doi:
Intravital imaging of the anterior segment by lightsheet microscopy Open Access
Yueh-Feng Wu; Li-An Chu; Wei-Kun Chang; Ann-Shyn Chiang; Bi-Chang Chen; Hsin-Yuan Tan; Ming-Kai Pan; Sung-Jan Lin
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 385. doi:
Anterior Segment Ultrasound Biomicroscopy Image Analysis Correlation with Physical Eye Exam Findings Open Access
Anusha Saga; Camilo Martinez; Moran Roni Levin; William Madigan; Janet L Alexander
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 386. doi:
Ultrasound biomicroscopy image analysis technique for the human iris Open Access
Trisha Miglani; Michael Chang; Moran Roni Levin; Janet Leath Alexander
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 387. doi:
Determination of the protective properties of Ophthalmic Viscosurgical Devices through an automatic segmentation pipeline of the anterior segment in porcine eyes using OCT Open Access
Philipp Matten; Melanie Wuest; Olivier Findl; Rainer A. Leitgeb; Wolfgang Drexler
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 388. doi:
Full Circumferential 3D Reconstruction of Schlemm’s Canal in Living Human Using Megahertz Swept Source OCT Open Access
Xinwen Yao; Yijie Ho; Jacqueline Chua; Damon Wong; Bingyao Tan; Leopold Schmetterer
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 389. doi:
Comparison of ocular parameters in cataract surgery candidates using different biometric devices Open Access
Rivkah Lender; Devora Kurland; Riki Greenberger; Zipora Boim; Lee Ben-Yaakov; Itay Chowers; Hadas Ben-Eli
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 390. doi:
Heidelberg Evaluation of the Iris: New Considerations Open Access
Gloria Wu; Ramtin Poustinchi; Ting-I Sung; Savannah Korte; Brian Nguyen
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 391. doi:
Evaluation of different OCT systems in quantitative imaging of Schlemm's Canal in human Open Access
Xuan Wu; Jinyuan Gan; Adeline Lam; Jacqueline Chua; Damon Wong; Bingyao Tan; Leopold Schmetterer; Xinwen Yao
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 392. doi:
Delineating the role of neural crest- and endothelial-derived FOXC2 in Schlemm’s Canal morphogenesis Open Access
Pieter R Norden; Lisa Beckmann; Zhen Cai; Xian Zhang; David Andrew Miller; Hao Zhang; Tsutomu Kume
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 393. doi:
Measuring Anterior Chamber Flare using Novel Slit-Lamp Imaging Technique Open Access
Muhammad Sohail Halim; Adithi D Chakravarthy; Neil L Onghanseng; Muhammad Hassan; Maria Soledad Ormaechea; Murat Hasanreisoglu; Wataru Matsumiya; Gunay Uludag; Anh NT Tran; Yasir J Sepah; Mahadevan Subramaniam; Quan Dong Nguyen
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 394. doi:
Ocular heterotopic bone formation in guinea pig: A case report with 7 months follow-up using advanced ophthalmic imaging technology Open Access
SO GOTO; Qiurong Zhu; Kelly Jensen; Josue Torres; Christine F Wildsoet
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 395. doi:
Effect of zoster vaccination on rates of herpes zoster ophthalmicus and herpes zoster in Australia Open Access
Sachin Phakey; Sophie Rogers; Anthony John Hall; Lyndell L Lim
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 396. doi:
Effects of Topical Glycyrrhizin Application on the Normal Ocular Surface Open Access
Sharon A McClellan; Mallika Somayajulu; Denise Bessert; Ahalya Pitchaikannu; Bao Chau Nguyen; Linda D Hazlett
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 397. doi:
RvD2 Counter-regulates Histamine-induced [Ca2+]i Increase and Mucin Secretion by Receptor Specific Protein Kinases in Rat Conjunctival Goblet Cells Open Access
Menglu Yang; Nora Botten; Robin Hodges; Tor P Utheim; Charles N Serhan; Darlene A Dartt
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 398. doi:
The effect of blocking substance P in reducing ocular redness Open Access
Shudan Wang; Lingjia Liu; Tomas Blanco; shuyan zhu; Kunpeng Pang; Hongyan Ge; Yihe Chen; Reza Dana
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 399. doi:
Synergistic activity of a peptide mimic with quinolones and cephalosporins against Staphylococcus aureus Open Access
Manjulatha Sara; Rajesh Kuppusamy; Madeeha Afzal; Mahjabeen Khan; Muhammad Yasir; Parthasarathi Kalaiselvan; Alex Hui; Naresh Kumar; Mark D P Willcox
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 400. doi:
Antiviral effect of multipurpose contact lens disinfecting solutions against coronavirus Open Access
Muhammad Yasir; Ajay Vijay Kumar; Mark Willcox
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 401. doi:
Hybrid Derivative of Cathelicidin (LL-37) and Human Beta-Defensin Against Gram-Positive Bacteria: A Novel Approach for the Treatment of Bacterial Keratitis Open Access
Darren S J Ting; Dalia Said; Mario Nubile; Leonardo Mastropasqua; Veluchamy A Barathi; Roger Beuerman; Rajamani Lakshminarayanan; Imran Mohammed; Harminder Dua
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 402. doi:
Antimicrobial susceptibility of Staphylococcus aureus from different ocular conditions Open Access
Madeeha Afzal; Ajay Kumar Vijay; Fiona Stapleton; Mark Willcox
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 403. doi:
Acute Adenoviral Conjunctivitis Treatment: A Phase 2 Interim Analysis of OKG-0301 Open Access
Stephanie L Watson; Robert Casson; Mei-Ling Tay-Kearney; Eric Daniels; Brian Strem; Paul Giles; Nitin Verma; Naomi Liebenberg; Hans Bloom; Fred Faigenbaum; Mark Daniell
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 404. doi:
Resolvin D1 (RvD1) as an Adjunct Anti-inflammatory Therapy to Treat Bacterial Endophthalmitis. Open Access
Pawan Kumar Singh; Sukhvinder Singh; Ashok Kumar
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 405. doi:
The Bacterial Ocular Surveillance System (BOSS): 2017 report Open Access
Maria Cabrera-Aguas; Pauline Khoo; Mia Zhang; Jason Daley; Monica Lahra; Stephanie L Watson
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 406. doi:
Lacritin Bactericidal Peptide N-104 Binds Surface-Exposed Lipoprotein YaiW, a Known Peptide Transporter Open Access
Mohammad Sharifian Gh.; Mihaela G Gadjeva; Gordon W Laurie
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 407. doi:
Minimal persistent inflammation during the silent phase of allergic conjunctivitis observed with in vivo confocal microscopy Open Access
Zahra Tajbakhsh; Isabelle Jalbert; Fiona Stapleton; Ali Alghamdi; Paul Gray; Betina Altavilla; Blanka Golebiowski
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 408. doi:
Therapeutic potential of a gK peptide for control of ocular HSV-1 infection Open Access
Shaohui Wang; Jack Yu; Kati Tormanen; Ujjaldeep Jaggi; Homayon Ghiasi
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 409. doi:
Sensitivity to netilmicin in infectious keratitis in Mexico in the period 2009 to 2017. Open Access
Francisco Beltran; Kristian Vázquez-Rom; José Arturo Oyervides-Alvarado; Laura Alejandra González-Dibildox; Nallely Ramos Betancourt; Manuel Garza Leon; Everardo Hernandez-Quintela
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 410. doi:
Are COVID-19 Antivirals Active against Adenovirus? Open Access
Eric G Romanowski; Kathleen A Yates; John Eric Romanowski; Regis P Kowalski
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 411. doi:
Effectiveness of Bilastine ophthalmic formulation for the treatment of allergic conjunctivitis Open Access
Paul J Gomes; Joseph B Ciolino; Gail Torkildsen; Ana Gonzalo; Gonzalo Hernández; Nieves Fernández
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 412. doi:
Immunoregulatory and amyloid-clearing phenotypes of conditional miR-155-depleted microglia in the retina of AD-model mice Open Access
Haoshen Shi; Yosef Koronyo; Dieu-Trang Fuchs; Julia Sheyn; Keith L. Black; Zhuoran Yin; Oleg Butovsky; Maya Koronyo-Hamaoui
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 413. doi:
In Vitro Potency of Tobramycin Against Common Bacterial Pathogens Implicated in Blepharitis Open Access
James E Deom; Megan E Cavet; Christine M Sanfilippo; Heleen H DeCory
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 414. doi:
Defining clinically meaningful improvement in ocular itching following treatment with reproxalap in an allergic conjunctivitis field trial Open Access
Yesha Raval; Paul J Gomes; Bill Cavanagh; Todd C. Brady
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 415. doi:
Bacterial metalloproteases inhibit epithelial cell migration and wound healing Open Access
Robert M Q Shanks; Mohammed Al Higaylan; Nicholas Stella; Kimberly M Brothers; Patrick H Thibodeau
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 416. doi:
Photoaocoustic determination of methicillin resistance in Staphylococcus aureus in ocular infections Open Access
Vishal Jhanji; Robert Edgar; Anie-Pier Samson; Regis P Kowalski; John Viator
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 417. doi:
Fibrinogen in Microglia-Mediated Inflammation in Diabetic Retinopathy Open Access
Borna Sarker; Sandra M Cardona; Difernando Vanegas; Kaira Church; Andrew S Mendiola; Astrid Cardona
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 418. doi:
The suppressive effect of ICP22 on CD80 promoter is altered by a recombinant virus lacking CD80 binding site Open Access
Harry Matundan; Shaohui Wang; Ujjaldeep Jaggi; Jack Yu; Homayon Ghiasi
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 419. doi:
Antimicrobial activity of a peptide mimic against Pseudomonas aeruginosa in solution and when immobilised onto contact lenses. Open Access
Parthasarathi Kalaiselvan; Rajesh Kuppusamy; Naresh Kumar; Mark Willcox
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 420. doi:
Safety Margins of Anti-VEGF Therapy using Treat and Extend Treatment Protocol – Lessons from the COVID-19 Pandemic Open Access
Ana Navarrete; Brice Vofo; Katherine Matos; Antonio Rivera; Jaime Levy; Itay Chowers
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 421. doi:
Characterizing Long-term Vision Change and Intravitreal Anti-VEGF Treatment Pattern Among Neovascular Age-Related Macular Degeneration (nAMD) Patients in the US: Analysis of the Vestrum D... Open Access
Cecile Truong; Glenn Yiu; Shih-Chen Chang; Jeffrey Willis; Nicholas Boucher; Fabio Ishii; Kemal Asik; Priya Kulkarni
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 422. doi:
Neovascular age-related macular degeneration (nAMD) treated with intravitreal aflibercept (IVT-AFL) treat-and-extend (T&E): post-hoc analysis of injection intensive (I-I) requirement ... Open Access
Sebastian Wolf; Frank G Holz; Philip Hykin; Edoardo Midena; Eric H Souied; George Lambrou; Tobias Machewitz; Helmut Allmeier; Paul Mitchell
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 423. doi:
Task shifting of intravitreal injections from physicians to nurses: a qualitative study Open Access
Stine Bolme; Dordi Austeng; Kari Hanne Gjeilo
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 424. doi:
Efficacy and safety of intravitreal aflibercept (IVT-AFL) treat-and-extend (T&E) compared with fixed dosing (q8) for neovascular age-related macular degeneration (nAMD): The AZURE stu... Open Access
Laurent Kodjikian; Lluís Arias Barquet; András Papp; Peter Kertes; Edoardo Midena; Jan Ernest; Rufino Silva; Thomas Schmelter; Tobias Niesen; Sergio Leal
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 425. doi:
HAWK and HARRIER 48-week data: potential for treatment interval extension in patients with nAMD disease activity at Week 16 Open Access
Ramin Tadayoni; Glenn J Jaffe; Frank G Holz; Ursula Schmidt-Erfurth; Kanji Takahashi; Gemmy Chui Ming Cheung; Seenu Hariprasad; Kinfemichael Gedif; Rasmus Olsen; Catherine Best; Peter K Kaiser
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 426. doi:
Safety of intravitreal pegcetacoplan in patients with neovascular age-related macular degeneration receiving anti-VEGF therapy Open Access
Allen Hu; Daniel Esmaili; Ramiro Ribiero; Caleb Bliss; Daniel Jones; David M Brown
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 427. doi:
Faricimab in Neovascular Age-Related Macular Degeneration: 1-Year Efficacy, Safety, and Durability in the Phase 3 TENAYA and LUCERNE Trials Open Access
Arshad M. Khanani; Jeffrey Heier; Carlos Quezada Ruiz; Hugh Lin; David Silverman; Christopher Brittain; Jane Ives; Balakumar Swaminathan; Karen Basu; Tien Y Wong
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 428. doi:
Dual angiopoietin-2 and VEGF-A inhibition with faricimab in neovascular age-related macular degeneration: phase 3 TENAYA and LUCERNE trial design Open Access
Robyn H Guymer; Carlos Quezada Ruiz; Jeffrey R Willis; David Silverman; Jane Ives; Karen Basu; Balakumar Swaminathan; Aachal Kotecha; Heather Boston; Hugh Lin
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 429. doi:
Risk Factors for Acute Elevated Intraocular Pressure after Intravitreal Anti-VEGF Injections Open Access
Stephen LoBue; Abenet Michael; Alan Guagliardo; Tom Chang; Michael Davis; Steven Fish
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 430. doi:
Real-world analysis of brolucizumab in neovascular AMD Open Access
Vanessa Rave; Kayshaliya Sharma; Alan Wagner; Kapil Kapoor
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 431. doi:
Cost Efficacy and Challenges of Real-world Brolucizumab use for Neovascular AMD Open Access
Kayshaliya Sharma; Vanessa Rave; Alan Wagner; Kapil Kapoor
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 432. doi:
Association between retinal thickness variability and visual acuity outcome during anti-vascular endothelial therapy for neovascular age-related macular degeneration Open Access
Timothy Y Y Lai; Ricky Y K Lai
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 433. doi:
Intravitreal injection patterns between retina providers in treating Wet Age-Related Macular Degeneration in a single hospital-based setting Open Access
Cina Karimaghaei; Anika Tanwani; Amir Ali; Nida Safdar; Efstathia Polychronopoulou; Mary Schmitz-Brown; Jaafar El-Annan; Praveena Gupta
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 434. doi:
Assessment of retinal pigment epithelial detachment treatment response and impact of size on outcomes in neovascular age-related macular degeneration from the OSPREY study Open Access
Kubra Sarici; Leina Lunasco; Thuy K Le; Robert Zahid; Xiangyi Meng; Duriye Damla Sevgi; Sunil K. Srivastava; Jamie Reese; Justis P Ehlers
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 435. doi:
Efficacy of the Treat-and-Extend Regimen in the Management of Neovascular Age-Related Macular Degeneration: 7-Year Results of the RENO Study Open Access
Cecilia Romero; Jordyn Vannavong; Jonathan M. Dang; Aamir A. Aziz; Phoebe E Shappell; Adam Wadsworth; Fawwaz Siddiqui; Micaela Koci; Greggory M. Gahn; Nazrul Mojumder; Molly M. Hagen; Wei Yang; Jay Chhablani; Arshad M. Khanani
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 436. doi:
Real-world use of intravitreal aflibercept (IVT-AFL) in neovascular age-related macular degeneration (nAMD) in Italy: results from PERSEUS-IT at Years 1 and 2 Open Access
Massimo Nicolo’; Francesco Ciucci; Andrea Russo; Marco Nardi; Salvatore Torregrossa; Andrea Scupola; Maria Vadalà; Barbara Parolini
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 437. doi:
Efficacy and outcome predictors of long-term intravitreal anti-VEGF therapy in neovascular age-related macular degeneration following a strict treat-and-extend regimen. Open Access
Katja B Hatz
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 438. doi:
Frequency of anti-VEGF intravitreal injections (IVI) after post-injection endophthalmitis in patients with neovascular age related macular degeneration (nvAMD) Open Access
Natalia Magdalena Binczyk; David Plemel; Matthew Tennant
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 439. doi:
Treatment switch from aflibercept to ranibizumab pre-filled syringe in Canadian DME patients in a real-world setting: The PRECISE study Open Access
Michel Giunta; Ananda Kalevar; Pierre Trottier; Louis Caron; Sohel Somani; Raman Tuli; Ghassan Cordahi; Joanne Gavalakis; Eser Adiguzel
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 440. doi:
Analgesic Efficacy for anti-VEGF Intravitreal Injections Open Access
Garrett Oberst; Claire Fraser
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 441. doi:
Bacillary detachment (BD) in nAMD: Incidence, clinical features, and response to anti-VEGF therapy Open Access
Sari Yordi; Kubra Sarici; Robert Zahid; Leina Lunasco; Thuy K Le; Xiangyi Meng; Duriye Damla Sevgi; Jamie Reese; Sunil K. Srivastava; Justis P Ehlers
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 442. doi:
Evolution of macular atrophy in eyes with neovascular age-related macular degeneration treated with anti-VEGF agents compared to fellow dry AMD eyes Open Access
Miltiadis K Tsilimbaris; Stella Blazaki; Emmanouil Blavakis; Georgios Bontzos; Georgios Smoustopoulos; Eleni Dimitriou; Eirini Chatziralli; Anastasis Stavrakakis; Stamatina Kabanarou; Tina Xirou; Gregory Chlouverakis
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 443. doi:
A tetravalent bispecific anti-angiopoietin-2/anti-VEGF antibody suppresses neovascular lesion and leakage in a laser-induced rat choroidal neovascularization model Open Access
Zsolt Ablonczy; James Lulo; Shengqin Wan; Christopher Schillo; Ciara O'Connor; Raj Patil; Andy Whitlock; Marco Muda
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 444. doi:
Visual acuity changes in eyes with poor presenting vision treated with bevacizumab for exudative age-related macular degeneration Open Access
Jonathan Siktberg; Sean Berkowitz; Shriji Patel
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 445. doi:
Levels of systemic VEGF-A and ranibizumab in the infant of a nursing mother receiving intravitreal ranibizumab therapy followed by a ‘pump and dump’ strategy Open Access
Verena Juncal; Radha Kohly; Samara B Marafon; Natalia Albuquerque Lucena Figueiredo; Liran Hostovsky; Yenge Diambomba; Keyvan Koushan; Rajeev H Muni
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 446. doi:
Toward a Non-Invasive Solution of Wet AMD: Sunitinib, Pazopanib, and Axitinib Eyedrops versus Intraocular Injection of Aflibercept Open Access
Kyoung-Hee Kim; Joo Young Oh; Daegeun Cho; Myungjo J. J. Kim
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 447. doi:
Anti-VEGF drugs clearly decrease phagocytic ability of retinal microglia. Open Access
Peter Heiduschka; Yahan Zhang; Tanja Plagemann; Nicole Eter
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 448. doi:
The impact of treatment intensity over 3 years of real-world data of neovascular age-related macular degeneration Open Access
Olga Gkorou; Holly Joan Duncan; Jeffry Hogg; Lydia Grace Stone; Michelle Blyth; Lesley Brandes; Adele Devenport; Leanne Timms; James Stephen Talks
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 449. doi:
Sensitivity and Specificity of Reticular Pseudodrusen detection using multimodal imaging in Amish Population Open Access
Ayesha Nuri Karamat; Sowmya Srinivas; Muneeswar Nittala; Swetha Velaga; Jonathan L Haines; Dwight Stambolian; Srinivas R Sadda
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 450. doi:
Real World Efficacy and Safety of Brolucizumab in Neovascular AMD: The REBEL Study Open Access
Aamir Abdul Aziz; Arshad M. Khanani; Nikolas London; Molly M. Hagen; Carl J Danzig; Amol D Kulkarni; Veeral S Sheth; Chirag D Jhaveri; David Aaron Eichenbaum; Michael Singer
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 451. doi:
Longer term Visual Acuity Outcomes and Anti-Vascular Endothelial Growth Factor Therapy Intensity in Neovascular AMD, Diabetic Macular Edema and Retina Vein Occlusion–Related Macular Edema... Open Access
Thomas A Ciulla; John Pollack; David Williams
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 452. doi:
Ocular Inflammatory and Retinal Vascular Occlusive Adverse Events of Intravitreal anti-VEGF Injections: A Systematic Review and Network Meta-analysis Open Access
Belinda Jiao; Eunice You; Karl Chemali; Mélanie Hébert; Shicheng Jin; Ali Dirani
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 453. doi:
Emulated trial comparing the effectiveness of Bevacuzimab vs Aflibercept using an external control arm Open Access
Paul Taylor; Darren Thomas; Aaron Y Lee; Philipp L. Mueller; Roy Schwartz; Abraham Olvera-Barrios; Alasdair Warwick; Praveen J Patel; Tjebo Herren; Catherine Egan; Adnan Tufail
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 454. doi:
Variation in visual outcomes for neovascular age-related macular degeneration within and between practitioners Open Access
Vuong Nguyen; Daniel Barthelmes; Mark C Gillies
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 455. doi:
Real-world efficacy and safety of brolucizumab Open Access
Scott D. Walter; Nicholas J. Saba
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 456. doi:
Transient vision loss associated with aflibercept pre-filled syringes Open Access
Brittni Scruggs; Daniel J Lee; Merina Thomas; Ambar Faridi
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 457. doi:
Single-cell analysis reveals a compensatory role of Muller glia in a mouse retinitis pigmentosa model Open Access
Yohei Tomita; Chenxi Qiu; Edward Bull; William Allen; Yumi Kotoda; Zhongjie Fu
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 458. doi:
Single cell RNA-seq analysis to evaluate heterogeneity of cell populations in 3D-Bioprinted outer Blood-Retinal Barrier Models Open Access
Eric Nguyen; Russell Quinn; Min Jae Song; Tea Soon Park; Claire Malley; Marc Ferrer; Kapil Bharti
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 459. doi:
Transcriptomic and genomic mapping of embryonic development of the human fovea Open Access
Lin Zhang; Ruchen Cai; Yirong Peng
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 460. doi:
Single-cell RNA sequencing reveals early responses to degeneration in rods and cones of the rd10 retina Open Access
Duygu Karademir; Vyara Todorova; Marijana Samardzija; Lynn Jenny Alix Ebner; Christian Grimm
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 461. doi:
High-Fat Diet Alters the Retinal Transcriptome Independently of Gut Microbiome in Germ-Free Mice Open Access
David Dao; Urooba Nadeem; Bingqing Xie; Asadolah Movahedan; Mark D'Souza; Hugo Adrian Barba; Edward Xie; Eugene Chang; Dinanath Sulakhe; Dimitra Skondra
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 462. doi:
Single-cell RNA sequencing identifies unique gene expression patterns in the foveal and perifoveal human retina Open Access
Andrew P Voigt; Nathaniel Kevin Mullin; S Scott Whitmore; Todd E Scheetz; Edwin M Stone; Budd A. Tucker; Robert F Mullins
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 463. doi:
The shifting epigenetic landscape along the developmental trajectory of retinal ganglion cells Open Access
Xiuqian Mu; Yichen Ge; Jonathan Bard; Julien Kann; Mobin Cheng; Fuguo Wu; Tao Liu; jie wang
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 464. doi:
Episcleral venous pressure response to brain stem stimulation: effect of topical Lidocaine. Open Access
Clemens Strohmaier; Herbert A Reitsamer; Jeffrey W Kiel
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 465. doi:
Morphological Changes to Schlemm’s Canal and the Distal Aqueous Outflow Pathway in Monkey Eyes with Laser-Induced Ocular Hypertension Open Access
Shayna Sosnowik; David L Swain; Shan Fan; Carol B Toris; Haiyan Gong
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 466. doi:
Caveolin-1 mediates relaxation of trabecular meshwork cells to chronic mechanical stretch via protein kinase C Open Access
Michael Lucio De Ieso; Megan Kuhn; Michael H Elliott; Daniel W Stamer
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 467. doi:
Genetic susceptibility to Loxl1 knockout-induced elastosis in a mouse model Open Access
Heather Schmitt; TeddiJo Watkins; Kristyn Hake; Megan Kuhn; Guorong Li; Daniel W Stamer; Michael A Hauser
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 468. doi:
Vasoregulator Effects on Outflow Resistance, Flow Patterns and Distal Vessels in the Conventional Outflow Pathway of Mouse and Human Eyes Open Access
Fiona S McDonnell; Todd Fleming; Megan Kuhn; Heather Schmitt; Kristin Perkumas; Joseph van Batenburg-Sherwood; Alex S Huang; Darryl R Overby; Daniel W Stamer
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 469. doi:
Examining the Effects of Glaucoma Medications on the Trabecular Outflow Pathway Using Glauconix Bioscience’s 3D-HTM™ Tissue Constructs Open Access
Andrea Unser; Feryan Ahmed; Hira Afzaal; Hunter Williams; Karen Yud Torrejon
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 470. doi:
Estimation of aqueous outflow facility before and after the microhook ab interno trabeculotomy Open Access
Masaki Tanito; Aika Tsutsui; Kaoru Manabe; Mihoko Mochiji
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 471. doi:
Variability in Schlemm Canal Anatomical Measurements Open Access
Mary Ben L Apatoff; Joel S Schuman; Mengling Liu; Gadi Wollstein; Hiroshi Ishikawa; Mengfei Wu; Ronald Zambrano; Ezekiel Ede; Priya Achanta; Larry Kagemann
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 472. doi:
Primary cilia and the reciprocal activation of AKT and SMAD2/3 regulate stretch-induced autophagy in trabecular meshwork cells Open Access
Myoungsup Sim; April Nettesheim; Angela Dixon; Paloma Borrajo Liton
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 473. doi:
The epidemiology of episcleral venous pressure (EVP) Open Access
Meghal Gagrani; Shan Fan; Vikas Gulati; Sachin Kedar; David Reed; Carol B Toris; Arthur J Sit; Sayoko E Moroi; Deepta Abhay Ghate
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 474. doi:
Mechanistic Role of Clusterin in Extracellular Matrix remodeling and Intraocular Pressure Homeostasis Open Access
Avinash Soundararajan; Padmanabhan P Pattabiraman
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 475. doi:
Inactivation of the Transcription Factor Sterol Regulatory Element Binding Protein (SREBP) Lowers Intraocular Pressure Open Access
Ting Wang; Jeffrey Rabinowitz; Padmanabhan P Pattabiraman
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 476. doi:
Cathepsin K Activity in Trabecular Meshwork Outflow Pathway Regulates Intraocular Pressure Homeostasis. Open Access
Sai Supriya Vuda; Sachin Anil Ghag; Padmanabhan P Pattabiraman
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 477. doi:
Dexamethasone-induced robust upregulation of ArgBP2, an actin crosslinking, ZO-1 and focal adhesion interacting adaptor protein, in human trabecular meshwork cells. Open Access
Vasantha Rao; William Bachman; Nikolai Skiba; Ayon Chakraborty; Camelia Eldawy; Rupalatha Maddala
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 478. doi:
Inhibition of TGFβ2-induced ocular hypertension using CRISPR interference Open Access
Naga pradeep Rayana; Weiming Mao; Chenna Kesavulu Sugali; Jiannong Dai
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 479. doi:
Alterations in Gene Expression of Human Trabecular Meshwork Cells in Response to Hyperglycemic Conditions Open Access
Chevy Singh; Avinash Soundararajan; Denis Jusufbegovic; John Lind; Padmanabhan P Pattabiraman
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 480. doi:
Decreased levels of Notch signaling in human trabecular meshwork cells cultured on rigid substrate Open Access
Kamesh Dhamodaran; Julia Staverosky; Janice A Vranka; VijayKrishna Raghunathan
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 481. doi:
Intracamerally transplanted stem cells changed the segmental outflow pattern and reduced intraocular pressure in a mouse glaucoma model Open Access
Yiqin Du
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 482. doi:
Automated machine learning detection of transcellular pores in Schlemm’s canal endothelial cells exposed to stretch Open Access
Justino Rodrigues; Anil Bharath; Darryl R Overby
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 483. doi:
Calcium-Dependent Transcellular Pore Formation in Schlemm’s Canal Endothelial Cells Open Access
Jacques Bertrand; Daniel W Stamer; Darryl R Overby
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 484. doi:
Activation of canonical Wnt signaling pathway inhibits dexamethasone-induced glucocorticoid receptor signaling in the trabecular meshwork Open Access
Chenna Kesavulu Sugali; Naga Pradeep Rayana; jiannong dai; Michael Peng; Sherri L Harris; Hannah Christine Webber; Shaohui Liu; Stephan Dixon; Priyanka Parekh; Elizabeth Martin; Louis B Cantor; Abbot F Clark; VijayKrishna Raghunathan; Weiming Mao
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 485. doi:
A20 may alter the fibrotic response within the trabecular meshwork by attenuating TGFβ2-TLR4 signaling crosstalk Open Access
Philip Mzyk; Colleen M McDowell
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 486. doi:
Trabecular meshwork pathology in a feline model of glaucoma due to LTBP2 mutation Open Access
Odalys Torne; Kazuya Oikawa; Julie A. Kiland; Leandro Teixeira; Gillian J McLellan
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 487. doi:
Pharmacological Sub-conjunctival Lymphatic Manipulation In Lymphatic Reporter Mice Open Access
Sindhu Saraswathy; Jong Yeon Lee; Young Gin Seong; Young-kwon Hong; Alex S Huang
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 488. doi:
Growth/Differentiation factor 15 (GDF-15) induced effects on intraocular pressure in mouse models Open Access
Rupalatha Maddala; Camelia Eldawy; William Bachman; Vasantha Rao
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 489. doi:
Knockout of the mechanotransducer, Integrin-α7, in trabecular meshwork cells affects signaling through Akt and mTOR Open Access
Julia Staverosky; VijayKrishna Raghunathan; Janice A Vranka
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 490. doi:
Small molecule Wnt signaling activators inhibit TGFβ signaling in the trabecular meshwork Open Access
Weiming Mao; Chenna Kesavulu Sugali; Naga Pradeep Rayana; jiannong dai; Michael Peng
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 491. doi:
Role of Notch Signaling Pathway in Steroid Induced Glaucoma Open Access
Sachin Anil Ghag; Padmanabhan P Pattabiraman
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 492. doi:
A novel mouse model of TGFβ2-induced ocular hypertension using lentiviral gene delivery Open Access
Shruti V Patil; Ramesh B Kasetti; Charles Kiehlbauch; J Cameron Millar; Gulab Zode
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 493. doi:
Micropump Device Capable of Measuring Outflow Facility in Awake Freely Moving Rats Open Access
Youssef Mohamed; Christopher L Passaglia
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 494. doi:
Determination of Quantitative Light Discomfort Thresholds in a Large Healthy Human Sample Open Access
Sarah Marie; Robert Montés-Micó; Alejandro Cerviño; Noelia Martínez-Albert; José Vicente García-Marqués
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 495. doi:
Spectral Properties of Glare or Positive Dysphotopsia for Different Types of Intraocular Lenses Open Access
Kamal Das; Akhil Kalapala
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 496. doi:
Novel device development to objectively assess “near-work” Open Access
Peter Wagner; Arthur Ho; Juno Kim
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 497. doi:
Accuracy of Kane and Hill-RBF V 2.0 Formulas Compared to Other Formulas for IOL Power Calculation Open Access
Cynthia C Jiang; Noah Michael Hodson; Daniel A Johnson; Ahmad Kheirkhah
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 498. doi:
Effect of pupil dilation on dark adapted perimetry using an Octopus 900 perimeter Open Access
Austin Igelman; Cristy Ann Ku; Mariana Matioli da Palma; Paul Yang; Mark E Pennesi
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 499. doi:
Age-related visual decline in companion dogs: a cross-sectional ERG study in a translational model species. Open Access
Freya M Mowat; Wojciech K Panek; Gilad Fefer; Mark Banghart; Grant Wagner; Hans D Westermeyer; Margaret Gruen; Natasha Olby
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 500. doi:
VISUAL ACUITY CHANGES WITH TIME FOLLOWING VISION THROUGH BANGERTER FILTERS Open Access
Jose Villa-Carpes; Jose M Marin-Sanchez; Enrique Josua Fernandez; Juan Manuel Bueno
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 501. doi:
Feasibility of quantitative Visual Acuity analysis for enriching Visual Acuity data collected in retina clinical trials Open Access
Raviv Katz; Filippos Vingopoulos; Rohan Bajaj; Luis Andres Lesmes; John Brown Miller
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 502. doi:
Personalized eye models for negative dysphotopsia assessment Open Access
Mihai State; Stefan Palkovits; Aixa Alarcon; Olivier Findl; Carmen Canovas; Patricia Piers
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 503. doi:
Gender Identification of faces under manipulated ocular optics Open Access
Clara Benedi-Garcia; SARA AISSATI; Miguel P Eckstein; Susana Marcos
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 504. doi:
Quantification of near word acuity thresholds with and without flankers for individuals with keratoconus Open Access
Sujata Rijal; Daniel R Coates; Jason D Marsack
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 505. doi:
Dance training to improve medical student ophthalmologic surgical skills Open Access
Kendall Goodyear; Danielle N Sarlo; Anne K Jensen; Amanda Swain; Horace DeLisser; Gil Binenbaum
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 506. doi:
Fixational Eye Movements depend on Fixation Task Open Access
Samantha Lin; Norick Bowers; Josselin Gautier; Austin John Roorda
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 507. doi:
Pediatric Assessment of Peripheral Visual Acuity Open Access
Eric R Ritchey; Ayeswarya Ravikumar; Kevin A. Butler; Chris Hunt; Joe Rappon
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 508. doi:
Comparing fixational stability of D1 baseball players as measured by Tracking Scanning Laser Ophthalmoscopy to healthy controls Open Access
Eric Van Meter; Judy Tran; Zachary Green; Christy Sheehy; Jacqueline Theis; Ethan A Rossi; Hope Reecher; Min Zhang; Charlotte Bolch; Nicole M Putnam
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 509. doi:
Machine learning classification of visual acuity curves for spectacle independence prediction Open Access
Mark David Jenkins Sanchez; Miguel Faria-Ribeiro; Linda Tsai; Stanley Bentow; Patricia Piers
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 510. doi:
The influence of stimulus defocus on two-photon visibility thresholds Open Access
Agnieszka Zielinska; Piotr Ciacka; Maciej Szkulmowski; Katarzyna Komar
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 511. doi:
Contrast sensitivity and Higher-Order Aberrations in Keratoconus subjects Open Access
Ravid Doron; David P Pinero; Einat Shneor
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 512. doi:
Keratoconus progression forecast by means of a time delay neural network Open Access
Marta Jiménez-García; IKRAM ISSARTI; Elke O. Kreps; Sorcha Ní Dhubhghaill; Carina Koppen; David Varssano; Jos J Rozema
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 513. doi:
Preclinical Estimation of Constants for Intraocular Lens Power Calculations Open Access
Michael Simpson
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 514. doi:
Seeing through the Boston Keratoprosthesis: A detailed optical assessment with natural scene imaging and characterization of the resolving power. Open Access
Pui-Chuen Hui; Leonardo A. Pereira; Shengtong Chen; Renald Dore; Elise Taniguchi; James Chodosh; Claes H Dohlman; Eleftherios I Paschalis
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 515. doi:
Age-related changes in the perception of self-motion and presence in virtual reality. Open Access
Wilson Luu; Barbara Zangerl; Michael Kalloniatis; Juno Kim
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 516. doi:
Normal values of mesopic and scotopic retinal sensitivity using microperimetry in a healthy reference population. Open Access
Isabel Fabelo Hidalgo; Consuelo Fernández-Nuñez; Nicolás Pérez-Llombet Quintana; Oswaldo Esteban Duran Carrasco; Maria Magdalena Alberto-Pestano; Marta Alonso Plasencia; Rodrigo Abreu-Gonzalez
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 517. doi:
Visual search performance across adulthood and in individuals with AMD Open Access
Catherine Agathos; Aude Tremolada; Bilel Benziane; Karine Lagrené; William H Seiple; Angelo Arleo
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 518. doi:
Vision simulator for cataract screening using holographic near-eye display with pupil tracker Open Access
Koray Kavakli; Gunes Aydindogan; Afsun Sahin; Hakan Urey
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 519. doi:
Contrast Sensitivity Function in Cataract Disease measured with Active Learning Open Access
Augustine Bannerman; Megan Kasetty; Filippos Vingopoulos; Itika Garg; Rebecca Silverman; Zhonghui Luo; June Cho; Raviv Katz; Alice Carlyle Lorch; Luis Andres Lesmes; John Brown Miller
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 520. doi:
Survey of long-term home monitoring of visual field in patients with chronic eye disease. Open Access
Selwyn Prea; Yu Xiang George Kong; Algis J Vingrys; Elizabeth K Baglin; Pyrawy Sivarajah; Robyn H Guymer
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 521. doi:
Developing a computational model of the retina for evaluating structure-function relationships in glaucoma Open Access
Kanjapat Temahivong; Chris Bradley; Robert W Massof
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 522. doi:
Dimension reduction reveals underlying factors of performance within a vision screening battery Open Access
Eric Seemiller; James Gaska; Marc Winterbottom; Eric Palmer; Eleanor O'Keefe; Elizabeth Shoda
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 523. doi:
Relationship between temporal L-cone flicker sensitivity and established clinical parameters in Stargardt’s disease Open Access
Cord R H Huchzermeyer; Julien Fars; Jan J Kremers
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 524. doi:
Evaluation of the novel Foraging Interactive D-prime (FInD) CSF Test Open Access
Jade Liu; Peter Bex; Ashutosh Jnawali; Fuensanta A Vera-Diaz
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 525. doi:
ERG and VEP Metrics of Melanopsin Sensitive Ganglion Cells Open Access
Jeff C Rabin; Julie Lovell; Neda Tahvilian; Annie Ku; Tayde Contreras; Jessica Carachure; Lydia Geabou; Jared Sies; Dung Nguyen
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 526. doi:
Explaining the Absence of Functional Tetrachromacy in Females with Four Cone Types Open Access
Dragos L Rezeanu; James Kuchenbecker; Rachel Barborek; Marcus Mazzaferri; Maureen Neitz; Jay Neitz
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 527. doi:
A new functional test sensitive to a reduction in light absorption by photoreceptors Open Access
Maryam Rezaei; Gerry Nour Chamaa; Clement Rodrigue; Judith Renaud; Remy Allard
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 528. doi:
Dissecting lipid contents in the distinct regions of native retinal rod disk membranes Open Access
Christopher Sander; Avery Sears; Antonio F. M. Pinto; Elliot H Choi; Shirin Kahremany; Hui Grace Jin; Els Pardon; Susie Suh; Zhiqian Dong; Jan Steyaert; Alan Saghatelian; Dorota Skowronska-Krawczyk; Philip David Kiser; Krzysztof Palczewski
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 529. doi:
TNFα-RUNX1 Pathway Regulates Retinal Endothelial Cell Survival and Response to Oxidative Stress Open Access
Hannah Whitmore; Daisy Y Shu; Magali Saint-Geniez; Leo A Kim
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 530. doi:
Allele-specific influence of seed polymorphism rs2168518 in hsa-miR-4513 on expression of neovascularization-associated genes Open Access
Christina Kiel; Tobias Strunz; Daniele Hasler; Gunter Meister; Felix Grassmann; Bernhard HF Weber
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 531. doi:
REDD1 ablation in Müller glia inhibits diabetes-induced retinal pathology in mice Open Access
William Phillip Miller; Allyson Lee Toro; Siddharth Sunilkumar; David L. Williamson; Michael D. Dennis
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 532. doi:
Expression and subcellular localization of USH1C/harmonin in the human retina Open Access
Uwe Wolfrum; Benjamin R Fadl; Mirjana M Becker; Daniel Sturm; Kirsten A. Wunderlich; Burcu Gür; Lew Kaplan; Matthew R Brooks; Antje A. Grosche; Anand Swaroop; Kerstin Nagel-Wolfrum
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 533. doi:
Diabetes-induced HDAC6-miR-34a pathway downregulates SIRT-1-miR-146a axis to promote stress-induced premature senescence and diabetic retinal microangiopathy Open Access
Manuela Bartoli; Ravirajsinh Jadeja; Hossameldin Abouhish; Shubhra Rajpurohit; Folami Lamoke Powell; Menaka Thounaojam; Pamela M Martin
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 534. doi:
Rab11, the TRAPPII complex, and phosphorylation regulate Rabin8 during ciliary trafficking of rhodopsin Open Access
Dusanka Deretic; Beatrice M Tam; Orson L Moritz; Theresa Fresquez
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 535. doi:
Perfluorodecalin-based oxygenated emulsion mitigates ocular hypoxia and inflammation after alkali burn Open Access
Kunpeng Pang; Sanming Li; shuyan zhu; Kathryn Pate; Jia Yin
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 536. doi:
Mouse retinal microvessels with single-file blood flow express alpha smooth muscle actin Open Access
Fei Shang; Jesse B Schallek
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 537. doi:
The anti-inflammatory and neuroprotective activity of novel hybrid molecule SA-10 in in vitro ischemic models Open Access
Suchismita Acharya; Lorea Gamboa Acha; Sudershan Gondi; Adnan Dibas; Charles Amankwa; Steven Roth; Biji Mathew
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 538. doi:
Retinal Blood Flow Dysregulation Precedes Neural Retinal Dysfunction in Type 2 Diabetic Mice Open Access
Taiji Nagaoka; Junya Hanaguri; Harumasa Yokota; Masahisa Watanabe; Satoru Yamagami
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 539. doi:
Regenerative effect of adipose derived mesenchymal stem cell on ganglion cells in the hypoxic organotypic retina culture Open Access
Meital Ben-Dov; Itay Nakdimon; Moshe Benhamou; Ainat Klein; Shulamit Schwartz; Anat Loewenstein; Adiel Barak; Aya Barzelay
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 540. doi:
Mutation of a caveolin binding motif in Na/K-ATPase activates the Nrf2 signaling pathway and attenuates experimental ischemic retinopathy Open Access
Jiayan Wang; Xiaoliang Wang; Sandrine V. Pierre; James W Gigantelli; Joseph I. Shapiro; Zijian Xie
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 541. doi:
Relationship between ocular blood flow and systemic organ blood flow in white rabbits with hemorrhagic shock Open Access
kento watanabe; Tomoaki Shiba; Tetsuya Komatsu; Akira Takahara; Yuichi Hori
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 542. doi:
Correlation of aqueous humor and plasma concentrations of amyloid and tau in older adults without dementia Open Access
Clayton Wisely; Cason Robbins; Justin Ma; Terry Kim; Dilraj Grewal; Sharon Fekrat
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 543. doi:
Post-injection Anti-inflammatory Drops Open Access
Daniel J Wisotsky; Danielle Strauss
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 544. doi:
Anti-VEGF Therapy and Elevated Intraocular Pressure: A Race-Based Analysis Open Access
Taj Nasser; Abenet Michael; Victor Chen; Ze Zhang
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 545. doi:
Effects of a proprietary de-novo IOP lowering compound (ID-65-CW69) on aqueous humor dynamics in monkeys Open Access
Shan Fan; Lisa Reid; Toni L. Goeser; Ganesh Prasanna; Carol B Toris
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 546. doi:
Predicting Pulsatile Ocular Blood Volume Non-invasively Open Access
Ryan Somogye; Cynthia J Roberts; Eberhard Spoerl; Karin R Pillunat; Lutz E Pillunat; Robert Small
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 547. doi:
Differences in retinal capillary blood flow and visual function in healthy male and female subjects of African and European descent Open Access
Brent A Siesky; Alon Harris; Nicholas Kalafatis; Louis R Pasquale; Aditya Belamkar; Joshua D. Shin; Ingrida Januleviciene; Giovanna Guidoboni; Alice Chandra Verticchio Vercellin
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 548. doi:
Orally administered dronabinol increases retinal blood flow without altering oxygen extraction in healthy subjects Open Access
Anton B Hommer; Nikolaus Hommer; Doreen Schmidl; Martin Kallab; Martin Bauer; René Werkmeister; Leopold Schmetterer; Marihan Abensperg-Traun; Gerhard Garhofer
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 549. doi:
Effects of phenylephrine on proximal and distal conventional outflow vessels in living animals Open Access
Guorong Li; Kevin Choy; Kristyn Hake; Sina Farsiu; C Ross Ethier; Daniel W Stamer
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 550. doi:
Differential effects of bimatoprost vs. bimatoprost free acid on outflow cell MMPs Open Access
Kristin Perkumas; Douglas J Rhee; Daniel W Stamer
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 551. doi:
Differential Responses of Human Juxtacanalicular and Trabecular Meshwork Beam Cells to Mechanical Stretch Open Access
Haven Roberts; Michael Lucio De Ieso; Daniel W Stamer
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 552. doi:
Metabolic status of the retina predicted using a hybrid mathematical model Open Access
Julia Arciero; Brendan Fry; Grace Mattingly; Amanda Albright; Brent A Siesky; Alice Chandra Verticchio Vercellin; Alon Harris
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 553. doi:
Single particle analysis of extracellular vesicles in aqueous humor from pediatric diseased eyes: a pilot study Open Access
Chen-Ching Peng; Liya Xu; Jesse L Berry
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 554. doi:
Proteomic alterations in the rat retina responding to the hypobaric hypoxic stress Open Access
Xiaorong Xin
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 555. doi:
Paracellular and intracellular transport in aqueous humor production: theoretical modeling and simulation Open Access
Riccardo Sacco; Greta Chiaravalli; Giovanna Guidoboni; Brent A Siesky; Alice Verticchio Vercellin; Alon Harris
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 556. doi:
Intraocular Pressure and Its Determinants in a Very Old Population. The Ural Very Old Study Open Access
Mukharram Bikbov; Gyulli Kazakbaeva; Songhomitra Panda-Jonas; Ellina Rakhimova; Jost Jonas
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 557. doi:
LOXL1-AS1 regulates extracellular matrix remodeling, mechanotransduction responses, and cellular morphology in human outflow cells. Open Access
Kristyn Hake; Heather Schmitt; William Johnson; Maria Gomez-Caraballo; Kristin Perkumas; Michael A Hauser; Daniel W Stamer
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 558. doi:
Physiology-enhanced data analytics to evaluate the effect of altitude on intraocular pressure Open Access
Giovanna Guidoboni; Marcela Szopos; Alice Chandra Verticchio Vercellin; Carlo Bruttini; Ivano Riva; Brent A Siesky; Alon Harris; Luciano Quaranta
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 559. doi:
Effect of altitude on retinal hemodynamics: A physiology-enhanced theoretical analysis Open Access
Lucia Carichino; Giovanna Guidoboni; Marcela Szopos; Alice Chandra Verticchio Vercellin; Carlo Bruttini; Ivano Riva; Brent A Siesky; Luciano Quaranta; Alon Harris
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 560. doi:
Biophysical Characterization of Antibody Biopolymer Conjugate (ABC) Platform for Improved Therapy of Retinal Vascular Diseases Open Access
Fernando Correa; Carrie Su; Long Pham; Namrata Prasad; Chandrani Chakraborty; Janine Lu; Rachel Jacobson; Bernd Jandeleit; Didier Benoit; Xiaojian Huang; Ashwath Jayagopal; Hong Liang; Victor Perlroth
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 561. doi:
Effect of Lumen Diameter on Intraocular Pressure in the Early Postoperative Period Following Tube-Shunt Implantation Open Access
Joey Tran; Luis E Vazquez; Wyatt N Deane
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 562. doi:
To compare the accuracy of intraocular lens calculation formulas in the prediction of postoperative refraction in eyes with short axial length (<22mm) Open Access
Sheetal Shirke; Nishant Gupta; Suheb Ahmed
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 563. doi:
The Risk of Posterior Capsule Rupture in Patients with Type 2 Diabetes Mellitus and Diabetic Retinopathy During Phacoemulsification Cataract Surgery Open Access
Valerie Jeanne Dawson; Jennifer Patnaik; Michael Wildes; Levi Bonnell; D. Claire Miller; Michael Taravella; Anne Lynch; Karen Christopher
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 564. doi:
Prednisolone and ketorolac versus ketorolac alone or dropless prophylaxis of macular thickening in cataract surgery Open Access
Jesper Hoeiberg Erichsen; Lars Morten Holm; Mads Forslund Jacobsen; Julie Lyng Forman; Line Kessel
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 565. doi:
Refractive outcomes using “Barrett True K Formula” for intraocular lens calculation in patients with radiated keratotomy Open Access
Alejandra Sanchez; Karla Zuniga; Ana Karen Escalona Brito; Eduardo Chavez-Mondragon
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 566. doi:
Cataract Surgery Refractive Outcomes in Long Eyes: A Comparison of 7 Formulas Open Access
Andrea Nichole Bordewyk; Shavini Athukorala; Catherine Seeger; Brett Ernst; Ingrid U Scott; Seth Pantanelli
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 567. doi:
Effect of Preoperative Anterior Chamber Depth and Intraocular Lens Power on Postoperative Pseudophakic Accommodation Following Monofocal Phacoemulsification Cataract Surgery Open Access
Sophia Joseph; Jennifer Eikenberry; David Keith Wallace
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 568. doi:
Evaluation of Three Minimally Invasive Glaucoma Surgeries (MIGS) Combined with Phacoemulsification for Treatment of Open-Angle Glaucoma and Visually Significant Cataract Open Access
Sabrina Chen; Himani Goyal; Leela Raju
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 569. doi:
Safety and Efficacy of Topical, Transzonular, and Intracanalicular Corticosteroids for the Prevention of Postoperative Inflammation after Cataract Surgery Open Access
Amy Lu; Monica Rizk; Tara O'Rourke; Ingrid U Scott; Seth Pantanelli
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 570. doi:
Evaluation of the effect of preloaded injector tip shapes on insertion resistance of the cornea and postoperative incision sizes in cataract surgery. Open Access
Tatsuya Sobajima; Takahiro Hishida; Shinji Nagasaka; Yasushi Soda
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 571. doi:
Initial Results of the PanOptix Intraocular Lens: A Comparison of Intermediate and Near Vision Acuities of PanOptix and Monofocal Lenses Open Access
Brandon Kingrey; Jeff Boomer; Tameka George
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 572. doi:
Phase 1 Study of OcuRing-K™ (Ketorolac Ophthalmic Implant) in Subjects Undergoing Cataract Surgery Open Access
Kenneth J Mandell; John D Sheppard; Iqbal Ike K. Ahmed; Richard L. Lindstrom; Ehsan Sadri; Farrell Tyson; Roberto Gonzalez-Salinas
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 573. doi:
Post-occlusion surge and anterior chamber stability in a new phacoemulsification machine with small-bore, dual-durometer aspiration tubing Open Access
Jianbo Zhou; Duru Han
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 574. doi:
An Evaluation of Commercially Available Ophthalmic Surgery Simulators for Continuous Curvilinear Capsulorrhexis Training Open Access
Nilesh Raval; Vivian Hawn; Mimi Kim; Xianhong Xie; Anurag Shrivastava
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 575. doi:
Early lensectomy in patients with pseudoexfoliation: long-term outcomes of effectiveness and safety Open Access
Ignacio Rodriguez-Una; Andrés Fernández-Vega; Montserrat Garcia-Diaz; Pedro Pablo Rodriguez-Calvo; Luis Fernandez-Vega-Cueto; José F. Alfonso; Jesus Merayo-Lloves
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 576. doi:
Patterns of Cataract Surgery Related Litigations in the United States from 2000-2020 Open Access
Daniel Zhu; Amanda Wong; Rohun Gupta; Albert S Li
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 577. doi:
Resident-performed immediate sequential bilateral cataract surgery during the COVID-19 pandemic Open Access
Tiffany A Chen; Stephanie P Chen; Tessnim Ahmad; Neel D Pasricha; Neeti Parikh; Saras Ramanathan
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 578. doi:
Multiplatform Input for Intraocular Lens Implant Calculation after Myopic Corneal Refractive Surgery Open Access
Randy Lu; Joanne Ho; Hoon Jung
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 579. doi:
Comparison of Visual Performance between Bifocal and Rotationally Asymmetric Multifocal with +1.5 Diopters Near Addition Intraocular Lenses Open Access
Hirotaka Tanabe; Tomohiro Shojo; Tomofusa Yamauchi; Kosuke Takase; Hitoshi Tabuchi
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 580. doi:
Outcomes of Resident-Performed Cataract Surgery in a Diverse Veterans Affairs Hospital System Population Open Access
Naomi E Gutkind; Elana Meer; Peiying Hua; Gui-Shuang Ying; Nirali Bhatt
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 581. doi:
Patient profile and outcomes regarding intraocular lens type selection in presbyopic hispanic population Open Access
Miguel Angel Hernandez-Delgado; Marcelo Salan-Gomez; Salvador Garza-Gonzalez; Monica Ivonne Herrera-Rodiguez; Sergio Eduardo Guevara-Quintanilla; Jorge Eugenio Valdez-Garcia
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 582. doi:
PhacoTrainer: Deep Learning for Activity Recognition in Cataract Surgical Videos Open Access
Hsu-Hang Yeh; Anjal Jain; Olivia Fox; Sophia Y Wang
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 583. doi:
Aqueous misdirection syndrome masking as myopic surprise: a case report and review of literature Open Access
Chung Shen Chean; Duminda Gabadage; Subhanjan Mukherji
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 584. doi:
Monofocal, Diffractive Trifocal and EDOF IOLs Open Access
Jihong Xie; George Lau
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 585. doi:
Rate of acute postoperative endophthalmitis after phacoemulsification using intracameral moxifloxacin Open Access
Justin Riffel; Anjulie Quick
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 586. doi:
Comparative Outcomes of Intravitreal Triamcinolone Acetonide-Moxifloxacin with Intracameral Dexamethasone-Moxifloxacin-Ketorolac in Cataract Surgery Open Access
Robin Kuriakose; Soungmin Cho; Saman Nassiri; Frank Hwang
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 587. doi:
A comparison of perception of pain in patients receiving neurolept anesthesia at 2 different time points for refractive laser assisted cataract surgery Open Access
Rishi B Gupta; Eric Tam; Hannah Chiu; Rajiv Maini; Ileana Gold; Sohel Somani
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 588. doi:
Resident-driven telehealth visits after cataract surgery: Minimizing exposures during COVID-19 Open Access
Stephanie P Chen; Tiffany A Chen; Tessnim Ahmad; Catherine Sun; Neeti Parikh; Saras Ramanathan
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 589. doi:
Efficacy of Preoperative Risk Stratification of Resident Phacoemulsification Surgery Open Access
Omar Moussa; Tahvi Frank; Ives A. Valenzuela; Joah Aliancy; Dan Gong; Lora R. Dagi Glass; Bryan Winn; George A. Cioffi; Royce Chen
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 590. doi:
Cataract Surgery Outcomes in Uveitis Patients: Experience at a Single Tertiary Referral Center Open Access
James M Samson; C Michael Samson; C Iris Samson
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 591. doi:
Does Ocular Biometry in Adults Change Over Time? Open Access
Nicholas K Chan; Reeti Gulati; Surendra Basti
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 592. doi:
Ophthalmological care during COVID-19 times. Perspectives from a Mexican eye healthcare system Open Access
Irving Armando Domínguez Varela; Gustavo Ortiz-Morales; Daniela Gomez-Elizondo; Andres Bustamante Arias; José A. Nava García; Jorge Eugenio Valdez-Garcia
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 593. doi:
Intraocular Lens Stabilisation with a novel implant: Our experience with a cohort of 72 patients Open Access
Ioannis Pallikaris; Ahmed Elmassry; Onurcan Sahin; Loukia Leonidou; Dimitris Liakopoulos; Harilaos S Ginis
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 594. doi:
Racial Disparities in Cataract Surgery Outcomes Open Access
Nakul Singh; Sila Bal; Alice Carlyle Lorch
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 595. doi:
Comparison of Gortex Sutured and Fibrin-Glued Secondary Intraocular Lenses, including Visual Acuity, Lens Tilt, and Adverse Events Open Access
Lauren Jeang; Logan Vander Woude; alex weaver; Siva S Radhakrishnan Iyer
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 596. doi:
Evaluating the accuracy and utility of a cataract simulation video for relieving patient anxiety Open Access
Anser A Abbas; Ruti Sella; Rebecca Lian; Spencer D Fuller; Sean S Bentley; Hideki Fukuoka; Natalie A Afshari
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 597. doi:
New Ophthalmic Viscosurgical Device (OVD) with Enhanced Hydroxyl Radical Scavenging Activity Open Access
William Joseph Erb; Madhu Ayyagari; George Lau
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 598. doi:
Advanced glycation endproducts are not elevated in human diabetic lens capsules when compared to age-matched nondiabetic lens capsules Open Access
Ram H Nagaraj; Johanna Rankenberg; Brandie Wagner; Jennifer Patnaik; Stefan Rakete; Marcus Glomb; Anne Lynch
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 599. doi:
A simplified nomogram for approximating intraocular lens (IOL) power in post-LASIK patients Open Access
Rebecca Lian; Francisco Malé; Ruti Sella; Helena Gali; Arturo Chayet; Natalie A Afshari
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 600. doi:
Electroretinography (ERG) Amplitude Changes in A Rat Retinal Ischemia Model Open Access
Lichun Zhong
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 601. doi:
Association between initial mfERG responses and myopic progression in children with and without prescription of Breath-O Correct orthokeratology lenses. Open Access
Kai Yip Choi; Tsz King Wong; Thomas Chuen Lam; Henry Ho-lung Chan
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 602. doi:
The effect of anti-VEGF injection loading dose in diabetic macular edema as measured by hand-held ERG system Open Access
Igor Kozak; John Centeno
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 603. doi:
A Comparison of Xenon- and LED-based Full-field Electroretinography in Patients with ABCA4-related Macular Dystrophy Open Access
Antonio Calcagni; Sophie L Glinton; Pearse A Keane; Michel Michaelides; Andrew Webster; Omar Abdul Rahman Mahroo; Anthony G Robson
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 604. doi:
Effect of bandpass filtering range on the mfERG parameters in patients undergoing screening for Plaquenil maculopathy Open Access
Abdullah Abou-Samra; Gaurav Kiri; Swetangi Bhaleeya; Radouil T Tzekov
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 605. doi:
Photopic electroretinograms recorded using a portable device at baseline in patients undergoing treatment for diabetic macular edema Open Access
Matthew Maguire; Omar Abdul Rahman Mahroo; Alistair Laidlaw; Christopher J Hammond
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 606. doi:
Effect of pupil size on fixed-luminance flicker full-field electroretinogram magnitude Open Access
Azadeh Mobasserian; Muhammad Sohail Halim; Jacklyn Joyce Hwang; Jonathan Regenold; Amir Akhavanrezayat; Hashem Ghoraba; Wataru Matsumiya; Negin Yavari; Irmak Karaca; Cigdem Yasar; Sherin Lajevardi; Brandon Huy Pham; Diana V Do; Quan Dong Nguyen
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 607. doi:
Spatial averaging effects on multifocal ERG amplitudes Open Access
Su-Yuan Yu; Sara Bijan; Gaurav Kiri; Swetangi Bhaleeya; Radouil T Tzekov
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 608. doi:
Photopic negative response in idiopathic intracranial hypertension recorded using a handheld device Open Access
Antony Raharja; Shaun Leo; Isabelle Chow; Mathura Indusegaran; Christopher J Hammond; Omar A Mahroo; Sui H Wong
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 609. doi:
The brighter the flash, the more synchronized the oscillatory potential response: A Hilbert transform analysis Open Access
Mercedes Gauthier; Anna Polosa; Jean-Marc Lina; Pierre Lachapelle
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 610. doi:
Evaluation of correlation between Diopsys® NOVA fixed-luminance flicker electroretinography and Diagnosys® full-field electroretinography Open Access
Jonathan Regenold; Hien Luong Doan; Amir Akhavanrezayat; Muhammad Sohail Halim; Azadeh Mobasserian; Jaclyn Joyce Hwang; Negin Yavari; Vahid Bazojoo; Wataru Matsumiya; Irmak Karaca; Brandon Pham; Brandon Chau Lam; Hassan Khojasteh; Sherin Lajevardi; Diana V Do; Quan Dong Nguyen
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 611. doi:
Changes in visual processing during progression of Tau accumulation and neurodegeneration in a mouse model of human tauopathy Open Access
Aleksandra Parka; Maiken Nedergaard; Florence Sotty; Bettina Laursen
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 612. doi:
The Heritability of Different Photopic Negative Response Components Explored in a Twin Study Open Access
Shaun Leo; Xiaofan Jiang; Taha Bhatti; Ambreen Tariq; Ting Shen; Katie Williams; Anthony G Robson; Pirro G Hysi; Christopher J Hammond; Omar Abdul Rahman Mahroo
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 613. doi:
Incidence of electronegative findings in tertiary ophthalmology referral centre Open Access
Dhimas Hari Sakti; Haipha Ali; Maria Korsakova; Nonna Saakova; Nina Mustafic; Clare Fraser; Robyn V Jamieson; Elisa Eleanor Cornish; John R Grigg
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 614. doi:
Visual acuity and contrast sensitivity are slightly modified in young asymptomatic relatives of Alzheimer’s disease patients Open Access
Jose Ramirez; Inés López Cuenca; Elena Salobrar-García; Jose A. Fernández-Albarral; Pilar Rojas; Lorena Elvira-Hurtado; Juan J. Salazar; Ana Barabash; Ana Ramirez; Rosa de Hoz
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 615. doi:
Spatial averaging effects on multifocal ERG peak times Open Access
Radouil T Tzekov; Sara Bijan; Gaurav Kiri; Swetangi Bhaleeya
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 616. doi:
The rise-time of the rod-driven electroretinogram a-wave measured in over 200 twins: association with age and estimation of heritability Open Access
Xiaofan Jiang; Taha Bhatti; Ambreen Tariq; Ting Shen; Katie Williams; Pirro G Hysi; Christopher J Hammond; Andrew Webster; Omar Abdul Rahman Mahroo
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 617. doi:
Ocular Characteristic in a Cohort of Neuronal Ceroid Lipofuscinoses/ Batten Disease Patients Open Access
Elisa Eleanor Cornish; Dhimas Hari Sakti; Clare Fraser; Trent Sandercoe; Michael M Jones; Neil A Rowe; Robyn V Jamieson; John R Grigg
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 618. doi:
Biofeedback fixation training in amblyopia Open Access
Mirella Telles Salgueiro Barboni; Otto Alexander Maneschg; Zoltán Zsolt Nagy; János Németh
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 619. doi:
Psychophysical Absolute Threshold in Mice is Inversely Related to Stimulus Duration Open Access
Sam LaMagna; Yumiko Umino; Ying Guo; Eduardo C Solessio
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 620. doi:
Blue light-induced alterations in visual cortex layer5pyramidal neuron and amelioration by Blue light blocking lenses(BBLs) in-Wistar rats Open Access
Nagarajan TN; Sudarshan S; Joshi Manjunath B; Manna Valiathan; Shonraj Ballae Ganeshrao
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 621. doi:
Development of a gaze-contingent electroretinogram system Open Access
Sara Aghajari; Peter Bex; Fuensanta A Vera-Diaz; Thanasis Panorgias
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 622. doi:
Temporal relationship between ERG waveforms and the firing patterns of rat retinal ganglion cells Open Access
Nicholas Johnson; Youssef Mohamed; Christopher L Passaglia
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 623. doi:
Investigating sound content in the early visual cortex of aphantasia participants Open Access
Belén María Montabes de la Cruz; Clement Abbatecola; Petra Vetter; Johanna Bergmann; Lucy Petro; Lars Muckli
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 624. doi:
Increased Cx43 and VEGF expression in acute nonarteritic anterior ischemic optic neuropathy induced with 577nm laser Open Access
Barbara Rangel Rangel; Louise Alessandra Mesentier-Louro; Ali Shariati; Roopa Dalal; Yaping Joyce Liao
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 625. doi:
Using Fixed-Force Goldmann Applanation Tonometry to measure the Ocular Pulse Amplitude Open Access
Joanne C Wen; Theodore Spaide; Yue Wu; Aaron Y Lee
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 626. doi:
Rate of bimatoprost implant biodegradation in the phase 3 ARTEMIS studies Open Access
Jacob W. Brubaker; Steven L Mansberger; James D. Branch; Kevin Wang; Michael R Robinson; Mitra Sehi
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 627. doi:
A Drug-Eluting Biomaterial Device for Reducing Post-Surgical Inflammation and Fibrosis in Glaucoma Patients Open Access
Alan Hibbitts; Mark Lemoine; Zülal Demir; Colm J O'Brien; Fergal O'Brien
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 628. doi:
The 24-2 Guided Progression Analysis can miss clear progression of glaucomatous damage identified on a single OCT follow-up test. Open Access
Donald C Hood; Emmanouil Tsamis; Sol La Bruna; Jennifer Grossman; Jeffrey M Liebmann; C Gustavo De Moraes
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 629. doi:
The agreement of STATPAC and visualFields statistical packages in visual field analyses Open Access
Herman Stubeda; Lesya Shuba; Marcelo Nicolela; Balwantray C Chauhan; Jayme R Vianna
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 630. doi:
Predictors of long-term intraocular pressure control after clear lens extraction in primary angle closure glaucoma: results from the EAGLE Open Access
David S Friedman; William Greig Mitchell; Augusto Azuara-Blanco; Jennifer Burr; Craig Ramsay; David Cooper; Claire Cochrane; John Norrie; Dolly Shuo-Teh Chang
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 631. doi:
Longitudinal Changes in the Central Visual Field and Risk of Visual Acuity Loss in Glaucoma Open Access
Tais Estrela; Alessandro A Jammal; Eduardo Bicalho Mariottoni; Leonardo Shigueoka; Felipe A Medeiros
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 632. doi:
Elucidating the role of EPOR signaling in an experimental model of neovascular age-related macular degeneration Open Access
Aniket Ramshekar; Eric Kunz; Colin Andrew Bretz; Brahim Chaqour; Mary Elizabeth Hartnett
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 633. doi:
Difference in characteristics of central serous chorioretinopathy with and without choroidal neovascularization on OCT angiography Open Access
Yuki Komuku; Xiaoyin Zhou; Takashi Araki; Hiroto Terasaki; Akiko Miki; Soichiro Kuwayama; Tomo Nishi; Takamasa Kinoshita; Fumi Gomi
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 634. doi:
An observational clinical study of the influence of phacoemulsification on choroidal neovascular membrane activity in age related macular degeneration Open Access
Jordan Reed; Nicholas Chung; George Benjamin Berrett; Mark Pearce; Jeffry Hogg; Sandro Di Simplicio
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 635. doi:
Myopic choroidal neovascularization: prognostic factors with a PRN regimen of Anti-VEGF therapy Open Access
Alicia Canalejo; Maribel Lopez-Galvez; Maria Fe Muñoz Moreno
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 636. doi:
Subretinal choroidal neovascularization in central serous chorioretinopathy resistant to mineralocorticoid receptor antagonists Open Access
Alexis Kassotis; Vlad Diaconita; Tongalp H Tezel
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 637. doi:
A Novel Tie2 activating monoclonal antibody ameliorates the lesion of choroidal neovascularization in monkey and mouse Open Access
Eun-Ah Lee; Beom Yong Park; Nuri Kang; Cheon Ho Park; Woen Sup Lee
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 638. doi:
Real-world outcomes for pro re nata and treat and extend regimens in exudative age-related macular degeneration Open Access
Holly Joan Duncan; Lydia Stone; Jeffry Hogg; Olga Gkorou; Michelle Blyth; Lesley Brandes; Adele Devenport; Leanne Timms; James Stephen Talks
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 639. doi:
Activity and pharmacokinetics of ICON-4, a New Antibody Targeting Tissue Factor Open Access
Jacques Gaudreault; Gabriela Burian; Thi-Sau MIgone
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 640. doi:
Serine Phosphorylation of IQGAP1 Regulates Choroidal Endothelial Activation and Neovascularization Open Access
Haibo Wang; Eric Kunz; Aniket Ramshekar; Mary Elizabeth Hartnett
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 641. doi:
The roles of SOCS3 in myeloid cell-derived neovascular endothelium formation in a laser-induced choroidal neovascularization mouse model Open Access
TIANXI WANG; Demetrios Tsirukis; Steve Cho; Ye Sun
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 642. doi:
The neurotrophin receptor p75NTR as a new player in the development of choroidal neovascularization Open Access
Paula Virginia Subirada Caldarone; Maria Victoria Vaglienti; Maria Paula O`brien; Alejandra Jurado; Jose D Luna Pinto; Horacio Uri Saragovi; Maria Cecilia Sanchez; Agustín Anastasía; Pablo Federico Barcelona
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 643. doi:
Quantitative evaluation of type 1 and type 2 choroidal neovascularization components under treatment with projection-resolved optical coherence tomography angiography Open Access
Steven T Bailey; kotaro tsuboi; Qisheng You; Jie Wang; Yukun Guo; Christina J Flaxel; Thomas S Hwang; David Huang; Yali Jia
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 644. doi:
Removal of retinal neovascularization in DL-AAA rabbit model using concurrently applied ultrasound bursts and nanosecond laser pulses Open Access
Julia Fu; Yixin Yu; Yu Qin; Xinmai Yang; Xueding Wang; Yannis Mantas Paulus
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 645. doi:
Multimodal imaging and clinical characteristics of peripapillary choroidal neovascularization in age-related macular degeneration. Open Access
Donato Colantuono; Eric H Souied; Francesca Amoroso; Vittorio Capuano; Giuseppe Querques; Alexandra Miere
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 646. doi:
Cellular origins of VEGF family members in laser-induced choroidal neovascularization using single-cell transcriptomic analysis. Open Access
Sook Hyun Chung; Brian Quang Dang; Glenn Yiu
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 647. doi:
DARC as a biomarker of endothelial cell stress in retinal angiogenesis Open Access
M Francesca Cordeiro; Li Guo; Vy Luong; John Maddison; Paolo Corazza; Saad Younis
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 648. doi:
Anti-angiogenic activity of Complement Factor H in a laser-induced choroidal neovascularization mouse model Open Access
Adam Tellier; Sandeep Kumar; Robyn Biggs; Melissa Deck; Suresh Katti
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 649. doi:
Macular Neovascularization Associated with Central Serous Chorioretinopathy: Multimodal Imaging-Based Predictors Open Access
Thamolwan Surakiatchanukul; Supriya Arora; Dmitri Maltsev; Sumit Singh; Niroj Kumar Sahoo; Deepika Parameshwarappa; Alexei Kulikov; Claudio Iovino; Filippo Tatti; Ramkailash Gujar; Ramesh S Venkatesh; Nikitha Reddy; Ram Snehith; Enrico Peiretti; Marco Lupidi; Jay Chhablani
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 650. doi:
The efficacy evaluation study of the clinical eye drop formulation of the NOX inhibitor, SJP1804 and the design of a phase 1 clinical trial for the treatment of wet AMD. Open Access
Moon Jung Back; Nunggum Jung; Dong Gu Jeong; Dongha Lee; Eunhye Jo; Meehwa Choi; Jin Cheul Kim; Hyun Tae Kim; Soo Jin Lee; Sung Hwan Moon; Min Hyo Ki
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 651. doi:
Role of Plasmacytoid Dendritic Cells in the Homeostasis of Retinal Blood Flow Open Access
Gustavo Ortiz; Arsia Jamali; Deshea L Harris; Pedram Hamrah
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 652. doi:
Outcomes and risk of reactivation of myopic CNV: Multi-Centre Study with long term follow up Open Access
Moawiya Alshunnar; Roy Schwartz; Alasdair Warwick; Abraham Olvera-Barrios; Maria Pikoula; Darren Thomas; Aaron Y Lee; Spiros Denaxas; Catherine Egan; Usha Chakravarthy; Peck Lin Lip; Paul Taylor; Adnan Tufail
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 653. doi:
Multiscale clinicopathologic correlation of canonical and non-canonical intraretinal neovascularization in age-related macular degeneration (AMD) Open Access
Jeffrey D. Messinger; Ling Chen; Andreas Berlin; Deepayan Kar; Tommaso Bacci; Chandrakumar Balaratnasingham; Randev Mendes; Daniela Ferrara; K Bailey Freund; Christine A Curcio
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 654. doi:
Choroidal thickness distribution among different types of CSCR based on multimodal-imaging based classification Open Access
Sonny Caplash; Supriya Arora; Dmitri Maltsev; Sumit Singh; Niroj Kumar Sahoo; Deepika Parameshwarappa; Tarun Arora; Alexei Kulikov; Claudio Iovino; Filippo Tatti; Ramkailash Gujar; Ramesh S Venkatesh; Nikitha Reddy; Ram Snehith; Enrico Peiretti; Jay Chhablani
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 655. doi:
Effect of Soft-Contact-Lens Wear on Post-Lens Tear-Film Osmolarity Open Access
Young Hyun Kim; Thien Nguyen; Meng C Lin; Cheng-Chun Peng; Clayton J Radke
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 656. doi:
Impact of monocular contact lens wear on tear film characteristics Open Access
Subam Basuthkar; Ulrike Stahl; Lyndon W Jones; Nancy Keir
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 657. doi:
Novel tear film dynamics underlying silicone hydrogel soft contact lens use Open Access
Hisataka Fujimoto; Shintaro Ochi; Tsutomu Yamashita; Arisu Masuda; Mito Yumi; Yasushi Inoue; Junichi Kiryu
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 658. doi:
Use of a Shack-Hartmann wavefront sensor to characterize the scattering properties of soft contact lenses Open Access
Minghan Chen
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 659. doi:
Recovery of corneal threshold and symptoms in symptomatic contact lens wearers Open Access
Ping Situ; Trefford Simpson; Carolyn Begley
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 660. doi:
Introduction of a new silicone hydrogel contact lens with surface modification of MPC polymer Open Access
James Wu; Charlie Shi; Vinay Sharma; David Cantu-Crouch
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 661. doi:
Surface softness comparison of select contact lenses by nanoindentation Open Access
Paul Oyler; Bob Tucker
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 662. doi:
Water gradient wettability and durability of a new monthly replacement contact lens Open Access
Pushkar Varde; Bob Tucker
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 663. doi:
Surface characterization of a new contact lens water gradient using fluorescent staining Open Access
Weihong Lang; Bob Tucker
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 664. doi:
Objective method for limbus detection of anterior segment topography Open Access
Abhishek Bhat; Kenneth Duy Tran; Christine W Sindt; Klara Barbarossa; Megan Bauer; Raymond Lum; Kuangmon Ashley Tuan
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 665. doi:
Efficacy of elastic Breath-O Correct orthokeratology on myopia control in a 1-year study period Open Access
Tsz King Wong; Kai Yip Choi; Henry Ho-lung Chan; Chuen Thomas Lam
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 666. doi:
Corneal Swelling after One Hour of Small and Large Diameter Scleral Lens Wear Open Access
Cherie B Nau; Ellen Shorter; Muriel Schornack; Jennifer Swingle Fogt; Amy Catherine Nau; Jennifer S Harthan
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 667. doi:
Relationship Between Add Power of Multifocal Soft Contact Lenses and Higher-Order Wavefront Aberrations in the Context of Myopia Management Open Access
Frank Spors; Jie Shen; Dorcas Tsang; Lance Earl McNaughton; Donald Joseph Egan
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 668. doi:
Treatment zone characteristics in children with slower axial elongation after orthokeratology treatment Open Access
Biyue Guo; Sin Wan Cheung; Pauline Cho
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 669. doi:
Clinical Subjective Performance of Two Daily Disposable Soft Contact Lenses Open Access
Lakshman N Subbaraman; Jason Miller; Bradley Giedd
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 670. doi:
Pilot study: Examining relationship among CLDEQ-8 defined classes, blink intervals, and tear film metrics Open Access
Greg Hofmann; Vrushali Korde; Nicole Franklin; Patricia Martin; Jie Xu; John R. Buch; Andrej Fogelton
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 671. doi:
Comparative analysis of the osmoprotective effects of a novel contact lens packaging solution on human corneal epithelial cells Open Access
Mirzi Grace Byrnes; Kimberly Millard; Deborah McGrath; Thomas Menzel; Marjorie Rah; William Reindel; Catherine Scheuer; Karl VanDerMeid
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 672. doi:
Antimicrobial Efficacy of Hydrogen Peroxide Contact Lens Care Products in the Presence of Contact Lenses Open Access
Rhonda Walters; Elise Miller; Cindy McAnally; Manal M Gabriel; Paul Shannon; Monica Crary
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 673. doi:
Fabrication of a MMP-9 triggered biomaterial for corneal wound healing Open Access
Susmita Bose; Chau Minh Phan; Evelyn Yim; Lyndon W Jones
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 674. doi:
Evaluation of Tear Film Surface Quality Non-Invasively During Soft Contact Lens Wear Open Access
Maryam Mousavi; Izabela K. Garaszczuk; Kelly K Nichols; D Robert Iskander
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 675. doi:
Multicenter Review of Indications for Scleral Lens Wear Open Access
Eric Kawulok; Muriel Schornack; Cherie B Nau; Christian Guier; Christina Wentz
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 676. doi:
Evaluation of Antiviral Efficacy for Contact Lens Care Products with Herpes Simplex Virus Open Access
Cynthia McAnally; Rhonda Walters; Manal M Gabriel; Paul Shannon
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 677. doi:
Scleral lenses for the management of corneal irregularities. Visual and aberrometric outcomes in Mexico. Open Access
Denise Loya; Gustavo Ortiz-Morales; Monica Herrera-Rodriguez; Julio Hernandez-Camarena; Guillermo Garcia de la Rosa; Jorge Eugenio Valdez-Garcia
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 678. doi:
Prevalence of Conjunctival Intraepithelial Neoplasia in Pterygium Specimens Open Access
Christopher Zhu; Menachem Weiss; Frank Scribbick III; Daniel A Johnson; Ahmad Kheirkhah
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 679. doi:
Comparison of ocular biometric parameters between Hispanic and non-Hispanic ethnicities Open Access
Brandon Chau Lam; Menachem Weiss; Christopher Zhu; Frank Jing; Cynthia C Jiang; Noah Michael Hodson; Daniel A Johnson; Ahmad Kheirkhah
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 680. doi:
The Impact of Frailty on Perioperative Outcomes after Open-Globe Injury in the Geriatric Population Open Access
Roger K Henry; Aditya Uppuluri; Paul D Langer; Marco A Zarbin; Neelakshi Bhagat
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 681. doi:
Corneal mechanical sensitivity in individuals with chronic pain Open Access
Brandon Baksh; Caroline Lieux; Anat Galor
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 682. doi:
Epidemiological Analysis of Causes of Ocular and Orbital Tissue Contusions Presenting to Emergency Departments Nationwide Open Access
Tyler Thomas Miller; Joshua Ong; Shaquille Josue-Coicou Charles; Kunal K. Dansingani
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 683. doi:
Ocular biomechanics during improvised explosive device blast Open Access
Alireza Karimi; Reza Razaghi; Christopher A Girkin; J Crawford C Downs
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 684. doi:
Revisit rates and associated costs after emergency room encounters for ophthalmic conditions Open Access
Amee D Azad; Evan Chen; Ravi Parikh; Benjamin Erickson; Prithvi Mruthyunjaya
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 685. doi:
A Spectroscopic Approach to Measuring Meibum Lipid Composition and Conformation in Donors with Sjogren’s Syndrome Open Access
Sravya Rao Veligandla; Anthony Ewurum; Jordan Swindel; Dr. Jeremy Clark; Douglas Borchman
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 686. doi:
Identification and spatial distribution of novel molecular features of adult human corneal cell subtypes Open Access
Guillermo Lehmann; Ann J Ligocki; Wen Fury; Christian Gutierrez; Christina Adler; Tao Yang; Min Ni; Yu Bai; Yi Wei; Carmelo Romano
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 687. doi:
Adult gonococcal conjunctivitis: case series in the United Kingdom (UK) Open Access
George Benjamin Berrett; Zoe Katarina Johnson; Matthias Schmid; Manjusha Narayanan; Francisco C Figueiredo
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 688. doi:
Effect of bevacizumab on the viability and metabolism of human corneal cells Open Access
Shayan Shokoohi; Alfonso Iovieno; Sonia Yeung
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 689. doi:
High endogenous Fibroblast Growth Factor 1 levels may explain regenerative response of rabbits to endothelial damage Open Access
David Eveleth; Grace Duffey; Lindsey Myers; Sarah Pizzuto; Jessica Weant
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 690. doi:
Analysis of the Protein Profile of Congenital Hereditary Endothelial Dystrophy Corneal Stroma after Keratoplasty Open Access
Mark Patrick Grogan; Rachida Bouhenni; Deepak P Edward; Payal Patel; Ruchi Mittal
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 691. doi:
Keratolytic and Keratostatic activity of Selenium Disulfide and its disease modifying role in Meibomian Gland Disease Open Access
Hila Epstein-Barash; Hadas Rapaport; Yair Alster; Omer Rafaeli
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 692. doi:
Lipogenic activity of Selenium Disulfide and its role in enhancing lipid production in Meibomian Glands Open Access
Yair Alster; Hila Epstein-Barash; Hadas Rapaport; Omer Rafaeli
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 693. doi:
Comparison of Pterygium Recurrence Rates between Attending and Resident Surgeons Open Access
Zachary Harbin; John Thompson; Hrishikesh Das; Lauren Deschner; Stephanie Seale; Ahmad Kheirkhah
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 694. doi:
Characteristics and Recurrence of Pterygium: A Single Center Study with a Long Follow-up Open Access
Waleed Alsarhani; Saeed Alshahrani; Mahmood Showail; Nawaf Alhabdan; Osama Alsumari; Abdullah Almalki; Abdulaziz Alsarhani; Adel Alluhaidan; Bader Alqahtani
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 695. doi:
Reducing Adenoviral Patient Infected Days (RAPID) Study: Correlation of adenoviral load with severity of adenoviral conjunctivitis and viral clearance over 21 days Open Access
Christina E Morettin; Jennifer S Harthan; Julia Huecker; AA Chamila D Perera; Tammy P Than; Ellen Shorter; Meredith Whiteside; Spencer Johnson; Andrew Hartwick; Mathew Margolis; Mary K Migneco; Christopher Alferez; Devon Camp; Len Haertter; Mae O Gordon
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 696. doi:
Dose- and time-dependent tear secretion induced by caffeine through dual P1 and P2 purinergic receptors activation in lacrimal gland Open Access
Meng-Tien Hsieh; Tsung-Han Lu; Chia-Yun Hsu; Ya-Jing Liu; Chia-Yu Hsu; Han-Hsin Chang; David Pei-Cheng Lin
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 697. doi:
Histatin -5 inhibits expression of pro-inflammatory cytokines through TLR- NF-kappa B pathway induced by hyperosmolar conditions in human corneal epithelial cells Open Access
Dhara Shah; Kyung-No Son; Sang Min Lee; Marwan Ali; Arun Balasubramaniam; Vinay Kumar Aakalu
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 698. doi:
EFFECTS OF DHT AND ESTRADIOL ON ROSIGLITAZONE-INDUCED LIPID PRODUCTION IN IMMORTALISED HUMAN MEIBOMIAN GLAND EPITHELIAL CELLS Open Access
Minh Anh Thu Phan; Michele C Madigan; Fiona Stapleton; Mark Willcox; Blanka Golebiowski
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 699. doi:
Galectin-3 Inhibition by a Small-Molecule Inhibitor Downregulates Fibrosis-Related Genes and Signaling Pathways in a Mouse Model of Corneal Fibrosis Open Access
Zhiyi Cao; Abdulraouf Ramadan; Fredrik Zetterberg; Noorjahan A Panjwani
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 700. doi:
Evaluation of meibography scores as age increases in Hispanic patients Open Access
Salvador Garza; Monica Herrera-Rodriguez; Miguel Angel Hernandez-Delgado; Marcelo Salan-Gomez; Sergio Eduardo Guevara-Quintanilla; Jorge E Valdez
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 701. doi:
The Anti-Scarring Role of Lycium Barbarum Polysaccharide on Cornea Epithelial-Stromal Injury Open Access
William Wong; Amy CY Lo; Yau Kei Chan; Kendrick Co Shih
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 702. doi:
Prevalence of Dry Eye and Meibomian Gland Dysfunction and their Associations in a Very Old Population. The Ural Very Old Study Open Access
Ellina Rakhimova; Mukharram Bikbov; Gyulli Kazakbaeva; Songhomitra Panda-Jonas; Ildar Ponomarev; Jost Jonas
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 703. doi:
Establishing the role of dietary lipids in meibogenesis Open Access
Seher Yuksel; Amber Wilkerson; Igor A Butovich
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 704. doi:
Secreted Ly-6/uPAR Related Protein-1 (SLURP1) suppresses epithelial cell proliferation by upregulating cell cycle inhibitors and downregulating cyclins and cyclin dependent kinases Open Access
Sudha Swamynathan; Gregory Campbell; Anil Tiwari; Shivalingappa K Swamynathan
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 705. doi:
Comparison of meibomian gland morphology in patients with evaporative dry eye versus healthy subjects. Open Access
Manuel Garza Leon; Ricaurte Ramiro Crespo Treviño; Anna Karen Salinas Sánchez; Francisco Amparo
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 706. doi:
Accelerated Aging in the Lacrimal Glands of Estrogen-deficient Aromatase (Aro) and Estrogen Receptor (ER) Knockout Mice Open Access
Yichen Bai; Xiaowei Yang; Xiaohe Lu; Xingwu Zhong; Dennis Lubahn; Lixing W Reneker
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 707. doi:
Conjunctival ultraviolet autofluorescence area is predictive of pterygium onset in young adults Open Access
David A Mackey; Gareth Lingham; Jason Kugelman; Jason Charng; Samantha SY Lee; Seyhan Yazar; Minas T Coroneo; David Alonso-Caneiro
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 708. doi:
Frequency of co-existing ocular surface neoplasms in pterygium biopsies: Experience from a South American country Open Access
Diego Ignacio Paredes Jalil; Carolina Aravena; Pablo Zoroquiain; Carlos Cartes Pinto; Andrea Cruzat; Rodolfo Garretón Cárcamo; Maria Carolina Ibañez Bruron; Paulina Liberman
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 709. doi:
Bioinformatic Analysis reveals possible mechanisms of Aniridic Keratopathy Open Access
Aarthi Krishnan; Adam Faranda; Samuel G Novo; Yan Wang; Melinda K Duncan
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 710. doi:
Differential Distribution of VEGF Receptor Dimers in Neuronal and Endothelial Cells Open Access
Joy Sarkar; Yuncin Luo; Qiang Zhou; Evguenia Ivakhnitskaia; Eitan Katz; Michael Sun; Daniel Lara; Victor H Guaiquil; Mark Rosenblatt
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 711. doi:
Microbiological spectrum and risk of transmission of infection from donor tissues of enucleated eyes harvested from septicaemic patients Open Access
Bhavana Sharma; Deepak Soni; Aditi Dubey; Samendra Karkhur; Deepayan Sarkar; Akhilesh Kumar; Suraj Kubrey; Vidhya Verma; Rajiv R Mohan
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 712. doi:
The Presence of SARS-CoV-2 in Human Corneal Tissue Open Access
Umangi Patel; YUAN LIU; Darlene Miller; Andrea Naranjo; Xiangxiang Liu; Jorge Maestre-Mesa; Elizabeth Fout; Richard K Lee; Sander R Dubovy
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 713. doi:
TESTOSTERONE AND PROGESTERONE IN HUMAN MEIBOMIAN GLAND EPITHELIAL CELLS DETECTED USING LC-MS Open Access
Blanka Golebiowski; Minh Anh Thu Phan; Martin Bucknall; Michele C Madigan; Mark Willcox; Fiona Stapleton
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 714. doi:
Characterizing Corneoscleral Permeability in Microgravity: A Novel Model for Testing Topical Ophthalmic Medication For Spaceflight Open Access
Daniel Bigley; Joshua Ong; Ahmad Chaudhry; Morgan V Fedorchak
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 715. doi:
Nonclinical Development of AG-920, A Topical Ocular Anesthetic for Analgesia During Intravitreal Injection Open Access
Rozemarijn S Verhoeven; Martin Uram; Audrey Schupp; Gary D Novack
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 716. doi:
Interim Analysis of Antibiotic Resistance from Bacterial Pathogens Collected in the 2020 ARMOR Study Open Access
Christine M Sanfilippo; Heleen H DeCory; Penny A Asbell
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 717. doi:
Glial cell line-derived neurotrophic factor in patients with age-related cataract Open Access
Alexander A Shpak; Alla B Guekht; Tatiana A Druzhkova; Anna A Troshina; Natalia Gulyaeva
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 718. doi:
Dose uniformity of loteprednol etabonate (submicron) ophthalmic gel 0.38% compared with prednisolone acetate ophthalmic suspension 1.0% Open Access
Zora T Marlowe; Megan E Cavet; Martin J Coffey
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 719. doi:
Occurrence of steroid-associated adverse events with loteprednol etabonate formulations Open Access
Megan E Cavet; Heleen H DeCory
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 720. doi:
The Synthesis and Testing of Rho Kinase Inhibitors Reversibly Coupled to Corticosteroids for the Treatment of Ocular Inflammatory Diseases Open Access
Mitchell A. deLong; Curtis Kelly; Karen Crews; Jill M. Sturdivant; Angie Glendenning; Briana Foley; Daphne Clancy; Monica Germann; Jeff White
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 721. doi:
In-vitro and In-vivo pharmacology of SAF312 as a TRPV1 inhibitor for ocular surface pain Open Access
Quint Medley; JUNZHENG YANG; John T Demirs; Julien Papillon; Yan Gao; YongYao Xu; James Chastain; Sameena Haque; Michela Montecchi Palmer; Aileen Wrynn
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 722. doi:
Modulation of In-vitro aggregation properties of TGFBIp peptides by osmolytes and toxicity of disaggregated amyloid fibrils Open Access
Anandalakshmi Venkatraman; Rajamani Lakshminarayanan; Jodhbir S Mehta
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 723. doi:
TGM2 inhibition with cysteamine hydrochloride does not impact corneal epithelial and stromal wound healing in vitro and in vivo Open Access
Andrea Minella; Tanvi J Chokshi; Jennifer Kang; Krista Cosert; M. Isabel Casanova; Megan M Gragg; Morgan A. W. Bowman; Michelle E Mccorkell; Nicole L Daley; Vijaykrishna Raghunathan; Brian Leonard; Christopher J Murphy; Sara M Thomasy
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 724. doi:
Topical ocular TRPV1 antagonist SAF312 demonstrated safety, low systemic exposure, and no anesthetic effect in healthy volunteers Open Access
Yifang Li; Monish Jain; Michela Montecchi Palmer; Sameena Haque; Kalliopi Stasi
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 725. doi:
OCULAR SAFETY PROFILE OF A NEW FORMULATION BASED ON HYPOCHLOROUS ACID IN RABBIT EYE Open Access
Giovanni Luca Romano; Francesca Lazzara; Federica Conti; Salvatore Giunta; Filippo Drago; Claudio Bucolo
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 726. doi:
Investigating Sodium Hexametaphosphate as a topical treatment for Band Keratopathy Open Access
Naomi Bennett; Lisa J Hill; Liam M Grover
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 727. doi:
The long-term clinical efficacy of recombinant human nerve growth factor in the treatment of neurotrophic keratitis Open Access
alice bruscolini; Marta Sacchetti; Antonietta Moramarco; Giuseppe Maria Albanese; Alberto Cerini; alessandro lambiase
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 728. doi:
Shear-stress dependent viscous properties of hyaluronic-based lubricants Open Access
Doreen Schmidl; Gerhard Garhofer; Leopold Schmetterer
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 729. doi:
Comparative In Vitro Activity of Antibiotics Frequently Used in the Management of Staphylococcal Blepharitis Open Access
Robert F Kissling; Christine M Sanfilippo; Heleen H DeCory
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 730. doi:
Safety of an Intracanalicular Dexamethasone Insert for the Treatment of Allergic Conjunctivitis: Pooled Post-hoc Analysis of Four Studies Open Access
John Meyer; Kenneth Kenyon; Michelle Sato; Steven M Silverstein; Edward J Meier; Karen Dewar; Erin Reilly; Paul J Gomes; Matthew Cheung; Michael H Goldstein
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 731. doi:
Effect of intravitreal steroid injection or implant on visual and imaging outcomes in patients with non-infectious uveitis Open Access
Philip DeSouza; Dhuruva Nidamarthi; Ala Moshiri; Glenn Yiu; Susanna S Park; Parisa Emami-Naeini
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 732. doi:
Changes in cytokine and growth factor levels at different time points after experimental glaucoma induction. Open Access
Jose A. Fernández-Albarral; Ana Ramirez; Rosa de Hoz; Meritxell López-Gallardo; Eva M. Marco; Elena Salobrar-García; Inés López Cuenca; Beatriz Martín-Sánchez; Elena Flores-Salguero; Marcelino Avilés-Trigueros; Manuel A Vidal-Sanz; Juan J. Salazar; Jose Ramirez
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 733. doi:
Evaluation of ocular irritancy based on cell membrane capacitance on a cruelty-free in vitro corneal model Open Access
Manuel Chacon; Natalia Vázquez; Mairobi Persinal-Medina; Sergio Alonso-Alonso; Ignacio Alcalde; Manuel Sánchez; Luis Fernandez-Vega-Cueto; Jesus Merayo-Lloves; Alvaro Meana
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 734. doi:
Dynamin Family Members and Protection of Ocular Surface Epithelia Open Access
Jinhong Pan; Rafael Martínez-Carrasco; M Elizabeth Fini
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 735. doi:
Pharmacokinetics of OTX-CSI, a Cyclosporine Intracanalicular Insert, in Surgically Induced Dry Eye Beagle Dogs Open Access
Andrew Vanslette; Charles D Blizzard; Art Driscoll; Matthew Cheung; Michael H Goldstein
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 736. doi:
Characterization and Development of a Novel Loteprednol Etabonate Eluting Adhesive Ocular Patch Open Access
Ann Yung; Shima Gholizadeh; Xi Chen; Nasim Annabi; Reza Dana
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 737. doi:
Titration of x-ray whole body radiation dose to optimize the murine model of ocular graft vs host disease Open Access
Jacklyn H Salmon; Jacob Nilles; Darby Roberts; Brian C Gilger
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 738. doi:
Cultured human uveal melanocytes express/secrete CXCL1 and CXCL2 constitutively and are increased by lipopolysaccharide via activation of Toll-like receptor 4 Open Access
Dan-Ning Hu; Ruihua Zhang; Wei-En Yang; Richard B Rosen; Shun-Fa Yang
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 739. doi:
Different mRNA expression patterns in cornea and limbus during the clinical course of sulfur mustard induced ocular injury in the rabbit model Open Access
Vered Horwitz; Inbal Egoz; maayan Cohen; Hila Gutman; Rellie Gez; Tamar Kadar; Shlomit Dachir; Ariel Gore
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 740. doi:
Impact of neurotrophic keratopathy on quality of life: A utility study Open Access
Sammie Eunsaem Fung; Kathryn S Park; Brian M. Fung; Erik Groessl; Daniel J. Ozzello; Don O. Kikkawa; Bobby S. Korn; Natalie A Afshari; Catherine Y. Liu
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 741. doi:
Substance P/Neurokinin-1 receptor pathway blockade alleviates epithelial stem cell deficiency Open Access
Romina M. Lasagni Vitar; Philippe Fonteyne; Paolo Rama; Giulio Ferrari
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 742. doi:
A single cell atlas of developing and adult cornea in steady state and disease conditions Open Access
Majlinda Lako; Joseph Collin; Rachel Queen; Darin Zerti; Sanja Bojic; Birthe Dorgau; Nicky Moyse; Marina Moya Molina; Chunbo Yang; Sunanda Dey; Lyle Armstrong; Francisco C Figueiredo
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 743. doi:
In situ-forming semi-interpenetrating network hydrogels for corneal regeneration: in vivo biological response Open Access
Fang Chen; Peter Le; Gabriella Fernandes-Cunha; David Christopher Mundy; David Myung
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 744. doi:
Supervised reduction of antiviral and steroid therapy in herpetic interstitial keratitis Open Access
Jackson Moran; Kevin Chung; Todd Margolis; Asim V. Farooq
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 745. doi:
Corneal sensitivity repeatability with a new non-contact air jet corneal esthesiometer and comparison with Cochet-Bonnet esthesiometer. Open Access
Javier Lozano; Alberto Barros; Jose Manuel Benitez del Castilo; Jesús Montero; Jesus Merayo-Lloves
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 746. doi:
Association between the systemic Omega-3 Index and corneal nerve architecture Open Access
Alexis Ceecee Zhang; Jennifer P Craig; Laura Elizabeth Downie
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 747. doi:
PEGlyated TRAIL alleviats alkali burn induced rat corneal fibrosis by targeting DR5 Open Access
Minjie Chen; Hui Lin; Stefanie Seo; Yumin Oh; Seulki Lee; Samuel C Yiu
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 748. doi:
Exosomes as a Novel Multitarget Approach to Promote Growth of Corneal Sensory Neurons Open Access
Eitan Katz; Victor H Guaiquil; Evguenia Ivakhnitskaia; Daniel Lara; Khandaker Anwar; Elmira Jalilian; Mark Rosenblatt; Ali R Djalilian
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 749. doi:
Diet-induced gut dysbiosis alters corneal immune cell distribution and gene expression in response to wounding Open Access
Kai Kang; Qiang Zhou; Lander McGinn; Yuncin Luo; Dimitra Skondra; Ali R Djalilian; Mark Rosenblatt
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 750. doi:
Collagen gels crosslinked by photoactivation of riboflavin for corneal defect repair Open Access
Youngyoon Amy Seo; Gabriella Fernandes-Cunha; Fang Chen; Peter Le; Caity Logan; David C Mundy; David Myung
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 751. doi:
In situ forming collagen-PEG hydrogel as a matrix therapy for corneal defects: 2 month in vivo response Open Access
Gabriella Fernandes-Cunha Rogers; Fang Chen; Peter Le; David C Mundy; Caitlin M Logan; David Myung
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 752. doi:
In Vitro and In Vivo Role of FGFR2 in Corneal Stromal Keratocytes Open Access
Roy Joseph; Om P Srivastava; Roswell R Pfister
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 753. doi:
Transient Mitomycin C treatment of human corneal epithelial cells impacts expression of autophagy and cytokine genes and increases phagocytosis Open Access
Sonali Pal Ghosh; Julie Thomasian; Beverly Karpinski; Gauri Tadvalkar; Maria Morasso; Stephen Brooks; Mary Ann Stepp
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 754. doi:
The role of pH measurement at presentation in predicting outcomes from acute ocular surface chemical injury Open Access
Emma Spowart; Sayali Pradhan; Charlotte Bruce; Borja Salvador-Culla; Gustavo Figueiredo; Francisco C Figueiredo
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 755. doi:
Differential regulatory role of normal and diabetic limbal epithelial cell-derived exosomes in limbal stromal cells Open Access
DRIRH KHARE; Adam Poe; Ruchi Shah; Alexander V Ljubimov; Mehrnoosh Saghizadeh
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 756. doi:
Validation of nanoconjugates targeting various diabetes-associated protein markers for gene therapy of diabetic keratopathy Open Access
Andrei A Kramerov; Ruchi Shah; Hui Ding; Mehrnoosh Saghizadeh; Julia Ljubimova; Alexander V Ljubimov
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 757. doi:
Oral mucosa culture system for ocular surface treatment avoiding the use of xenogeneic components Open Access
Alvaro Meana; Mairobi Persinal-Medina; Natalia Vázquez; Manuel Chacon; Sergio Alonso-Alonso; Carlos Fernández-Vega-González; Jose I Blazquez; Sara Llames; Jesus Merayo-Lloves
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 758. doi:
Organization of lamellae in the corneal stroma: Mouse models for better understanding of the pathomechanism of keratoconus Open Access
Uwe Hansen; Melanie Timmen; Martin Goette; Marie-Claire Schannne-Klein; Margaux Schmeltz; Clouthilde Raoux; Marion Bied; Gael Latour; Richard Stange; Thomas Pap; Nicole Eter; Maged Alnawaiseh
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 759. doi:
Epithelial-mesenchymal transition markers upregulation in corneal epithelial cells after UV-B irradiation which is irreversible with Resveratrol Open Access
Berbang Meshko; Marieke Domday; Stephanie Brosig; Claus Cursiefen; Maria Notara
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 760. doi:
A Living Biological Bandage for management of corneal injuries Open Access
Stephanie Poon; Kendrick Co Shih; Yau Kei Chan
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 761. doi:
A cellular model for Brittle Cornea Syndrome Open Access
Chloe Stanton; Camilla Drake; Amy Findlay; Zuhair Mustafa; Susan Campbell; Veronique Vitart
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 762. doi:
Expression of axon guidance proteins in the cornea and trigeminal ganglia and their role in cornea neuro-epithelium regeneration. Open Access
Victor H Guaiquil; Greigory Dimailig; Cissy Xiao; Daniel Lara; Qiang Zhou
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 763. doi:
Distal nerve degeneration in the cornea is initiated by oxidative stress. Open Access
Cristina Sánchez Fernández; Carlota Suarez-Barrio; Susana del Olmo Aguado; Carla Martin; Luis Fernandez-Vega-Cueto; Luis Manuel Quirós; Jesus Merayo-Lloves; Ignacio Alcalde
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 764. doi:
Rabbit limbal stem cells in vitro observation and their transplantation to rabbits Open Access
Julia Khorolskaya; Olga Aleksandrova; Daria Perepletchikova; Kirill Zhurenkov; Ilya Gavrilyik; Natalia Mikhailova; Miralda Blinova
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 765. doi:
Opsin 5 (OPN5) photoreceptors are induced in the mouse cornea following epithelial debridement. Open Access
Ethan Buhr; Nicolas M Diaz
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 766. doi:
Corneal Crosslinking Intracorneal Stress Measured by a Novel and Easily Implemented Differential Tonometry Method Open Access
Sean Joseph McCafferty; Mingwu Wang
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 767. doi:
Manifest Refraction Versus Wavefront Refraction in Patients with Keratoconus Open Access
Michael Lai; Steven Greenstein; John Gelles; Peter Hersh
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 768. doi:
Predicting keratoconus progression using deep learning Open Access
Naoko Kato; Hiroki Masumoto; Mao Tanabe; Chikako Sakai; Kazuno Negishi; Hidemasa Torii; Hitoshi Tabuchi; Kazuo Tsubota
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 769. doi:
Corneal imaging practices for keratoconus patients at an academic medical center Open Access
Alan W Kong; Tessnim Ahmad; Marcus L Turner; Neel D Pasricha; Maanasa Indaram
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 770. doi:
Regional Mechanical Deformation of Human Corneal Stroma during Intraocular Pressure Elevation Open Access
Nicholas Hazen; Keyton Clayson; Sunny Kwok; Xueliang Pan; Jun Liu
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 771. doi:
Outcomes of Intracorneal Ring Segments for Keratoconus at a Tertiary Care Center in the United Arab Emirates Open Access
shaikha aljneibi; Prateek Agarwal; Rony R Sayegh
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 772. doi:
Reliability of successive corneal tomography and biomechanical measurements by Pentacam® and Corvis ST® in keratoconus patients without treatment and after corneal crosslinking Open Access
Kassandra Xanthopoulou; Cristian Munteanu; Berthold Seitz; Michael W Belin; Elias Flockerzi
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 773. doi:
Keratoconus: Trends in Management and Adherence to Preferred Treatment Patterns Open Access
Glory Mgboji; Varshini Varadaraj; Uri Soiberman; Divya Srikumaran
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 774. doi:
Outcomes of corneal crosslinking for keratoconus in children and young adults Open Access
Solin Saleh; Euna B Koo; Scott R Lambert; Edward E Manche
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 775. doi:
Current Trends in the Holistic, Long-Term Management of Keratoconus Open Access
Amy Catherine Nau; Cherie B Nau; Muriel Schornack; Jennifer S Harthan; Jennifer Swingle Fogt; Ellen Shorter
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 776. doi:
Evaluation of Stress-Strain Index (SSI2) in Healthy and Keratoconic corneas Open Access
Ashkan Eliasy; Bernardo Teixeira Lopes; Ahmed Abass; Riccardo Vinciguerra; Susana Marcos; Ahmed Elsheikh
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 777. doi:
A novel diagnostic tool for Keratoconus and its severity Open Access
Einat Shneor; Ariela Gordon-Shaag; Arige Gedeon Abou Said
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 778. doi:
Molecular alterations in exosomes derived from corneal stromal cells of patients with keratoconus Open Access
Victor Lozano Iturbe; Luis Manuel Quirós; Luis Fernandez-Vega-Cueto; Carla Martin; Ignacio Alcalde; Helena Ordiales-Trabanco; Jesus Merayo-Lloves
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 779. doi:
Heartbeat Optical Coherence Elastography: Using Heartbeat to Assess Corneal Biomechanical Properties Open Access
Achuth Nair; Manmohan Singh; Salavat Aglyamov; Kirill Larin
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 780. doi:
Identifying the target genes of PPIP5K2 in relation to keratoconus Open Access
Theresa Akoto; Chunfang Gu; Jingwen Cai; Zhong Chen; Mitchell A Watsky; Stephen B Shears; Yutao Liu
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 781. doi:
The Role of PCSK1 in Keratoconus Pathogenesis in Two Mouse Models Open Access
Yutao Liu; Hongfang Yu; Anthony N Kuo; Amy Estes; Sylvia B Smith; Jingwen Cai
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 782. doi:
Substratum stiffness modulates the proliferation but not the motility of cultured corneal keratocytes in response to PDGF-BB Open Access
Krithika Iyer; David Schmidtke; Matthew Petroll; Victor Varner
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 783. doi:
Risk factors for the development of keratoconus in young adults Open Access
Gareth Lingham; David A Mackey; Samantha SY Lee; Seyhan Yazar; Elsie Chan; Elaine Chong
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 784. doi:
Corneal collagen cross-linking in children and developmentally delayed populations Open Access
Omar Shareef; Abdelrahman Elhusseiny; James Taekyoon Kwan; Hajirah N. Saeed
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 785. doi:
Mechanical analysis of an ocular globe, a required complexity during inflation test? Open Access
IKRAM ISSARTI; Carina Koppen; Jos J Rozema
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 786. doi:
A novel rebound technology-based method for measuring corneal sensitivity Open Access
Matjaz Mihelcic; Juha Päällysaho; Matti Raudasoja; Viktor Honkanen; Ville-Pekka Seppä; Mika Salkola; Petra Schollmayer
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 787. doi:
Computational modeling of the impact of corneal surgical procedures on regional stress distribution within the stroma Open Access
Hajar Hassaniardekani; Victor Varner; Matthew Petroll
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 788. doi:
Examining Cantilever Induced Epithelial Damage Open Access
O'Rese J Knight; Devin Hubbard; Noel Ziebarth; Hua Mei
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 789. doi:
Predictive modeling for singlet oxygen generated during Rose Bengal Photodynamic Antimicrobial Therapy Open Access
Jeffrey C Peterson; Yu-Cherng Chang; Irene Kochevar; Fabrice Manns; Jean-Marie A Parel
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 790. doi:
Elastic anisotropy of the cornea: comparison of non-contact AμT-OCE with mechanical tests Open Access
Mitchell Kirby; Ivan Pelivanov; Hon-Cin Liou; Ruikang Wang; Matthew O'Donnell; Tueng T Shen
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 791. doi:
Accelerated corneal cross-linking in pediatric patients with keratoconus from the northeast of Mexico: A 3-year follow-up Open Access
Luis Alberto Rodríguez; Victoria Holguin; Denise Loya
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 792. doi:
Metal Oxide Nanoparticles Induce Stiffening of Rabbit Corneal Fibroblasts in vitro Open Access
Krista Cosert; Jennifer Kang; Melinda Quan; Laura Van Winkle; Kent Pinkerton; Brian Leonard; Christopher J Murphy; Sara M Thomasy
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 793. doi:
Assessing the Effect of Intraocular Pressure on Elastic Wave Propagation Using Optical Coherence Elastography Open Access
Michael Sun; Taeyoon Son; Lara Nammari; Joseph Crutison; Harish Palnitkar; Qiang Zhou; Ghasem Yazdanpanah; Victor H Guaiquil; Ali R Djalilian; Dieter Klatt; Xincheng Yao; Thomas Royston; Mark Rosenblatt
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 794. doi:
Depth-dependent effects of intraocular pressure on phase-decorrelation OCT measurements Open Access
Brecken Blackburn; Matthew McPheeters; Michael W Jenkins; William J. Dupps; Andrew M Rollins
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 795. doi:
Modulating ocular surface pain through Neurokinin-1 receptor blockade Open Access
Giulio Ferrari; Romina M. Lasagni Vitar; Philippe Fonteyne; Paolo Rama
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 796. doi:
Accelerated regeneration of corneal endothelium after Descemet’s stripping mediated by the engineered fibroblast growth factor TTHX1114 Open Access
Sarah Pizzuto; Jessica Weant; Natalie A Afshari; David Eveleth
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 797. doi:
Immunomodulatory gene therapy for treatment of ocular graft vs host disease Open Access
Jacob Nilles; Darby Roberts; Beth Salmon; Matthew Hirsch; Brian C Gilger
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 798. doi:
Injection volume alters recombinant Adeno-associated Virus 8 ttansduction efficiency and biodistribution Open Access
Liujiang Song; Zhenwei Song; Telmo Llanga; Jacquelyn Bower; Matthew Hirsch
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 799. doi:
Analyzing lubricant eyedrop touchdown and motion on dry ocular surface Open Access
Muhammad Abdulrazik
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 800. doi:
Intracorneal sequential dosing of AAV-ArsB clears corneal opacity associated with mucopolysaccharidosis VI in a feline model Open Access
Brian C Gilger; Jacklyn H Salmon; Darby Roberts; Liujiang Song; Jacquelyn Bower; Matthew Hirsch
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 801. doi:
Morphology and cell density of the corneal endothelium of healthy Japanese eyes Open Access
Takashi Ono; Yosai Mori; Ryohei Nejima; Takuya Iwasaki; Kazunori Miyata
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 802. doi:
Metabolism of primary human corneal endothelial cell (HCEnC) cultures grown at ambient and 2.5% oxygen Open Access
Christian F Mueller; Sangita P Patel
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 803. doi:
Endothelial cell viability after DMEK graft preparation Open Access
Alina Miron; Anita Sajet; Esther A Groeneveld; Jet Kok; Mehtap Dedeci; Maloeke de Jong; Vicky Amo-Addae; Gerrit RJ Melles; Silke Oellerich; Jacqueline van der Wees
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 804. doi:
Molecular chaperones are direct binding partners in mitochondrial targeting of SLC4A11. Open Access
Moonjung Choi; Joseph A Bonanno
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 805. doi:
A porcine cornea model for testing corneal storage media formulations Open Access
Jana D'Amato Tothova; Laura Giurgola; Stefano Ferrari; Lorenzo Bosio; Claudio Gatto
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 806. doi:
Inducible Slc4a11 knock out in adult mice produces corneal edema through alteration of pump and barrier functions Open Access
Diego G. Ogando; Raji Shyam; Edward Taeyoon Kim; Yen-Chiao Wang; Chia-Yang Liu; Joseph A Bonanno
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 807. doi:
Cancer Risk in Patients with Fuchs Endothelial Corneal Dystrophy Open Access
Timothy T. Xu; Keith H Baratz; Michael P Fautsch; David O Hodge; Michael A Mahr
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 808. doi:
Topical ripasudil for the treatment of canine corneal endothelial dystrophy Open Access
Sarah R. Michalak; Sangwan Park; Soohyun Kim; M. Isabel Casanova; Morgan A. W. Bowman; Michelle Ferneding; Sara M Thomasy
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 809. doi:
A Novel Dual-Chamber Vial for Corneal Preservation Open Access
Joana Karanxha; Angela Gomez-Bedoya; Katrina N. Llanes; Patrice Jan Persad; Stephen D. Roper; William Buras; Elizabeth Fout; Alfonso L. Sabater
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 810. doi:
To determine the relationship between corneal endothelial parameterswith diabetes mellitus and diabetic retinopathy Open Access
ashok jha; Aditya Verma; AHMED ROSHDY ALAGORIE
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 811. doi:
Development of a French version of the Visual Function and Corneal Health Status (V-FUCHS) instrument for Fuchs endothelial corneal dystrophy (FECD) Open Access
Guillaume Albert Mullie; Alejandro Juarez; Antoine Etcheverry; Nassima Taleb; Tanguy Boutin; Johanna Choremis; Michèle Mabon; Julia C. Talajic; Charles-Édouard Giguère; Isabelle Brunette
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 812. doi:
Growth characteristics of primary human corneal endothelial cells (HCEnC) at ambient and 2.5% oxygen Open Access
Jamie Floss; Christian F Mueller; Maria Sousa; Sangita P Patel
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 813. doi:
Investigation of Oxidative Stress in Ex Vivo Corneal Endothelial Cells During Cell Culture and Expansion Open Access
Charlene Choo; Doug Chung; Anthony J Aldave
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 814. doi:
Hyperosmolar eye drops for diurnal corneal edema in Fuchs endothelial dystrophy: a double-blind randomized-controlled trial Open Access
Katrin Wacker; Daniel Zander; Daniel Böhringer; Marianne Fritz; Viviane Grewing; Thabo Lapp; Philip Maier; Thomas Reinhard
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 815. doi:
Hypothermia breaks down the barrier function of the corneal endothelium Open Access
Sudhir H Ranganath; M. Y. Thanuja; Manjunatha T D; Sangly P Srinivas
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 816. doi:
Deep neural network by transfer learning for the analysis of guttae in the patients with Fuchs endothelial corneal dystrophy Open Access
Kaito Narimoto; Naoki Okumura; Shohei Yamada; Kengo Okamura; Ayaka Izumi; Theofilos Tourtas; Friedrich E Kruse; Noriko Koizumi
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 817. doi:
Intraocular Inflammasome Activation in Pseudophakic Bullous Keratopathy Open Access
Andres Serrano; Angela Gomez-Bedoya; Enrique Salero; Arianna Tovar; Patrice Jan Persad; Roey Hadad; Guillermo Amescua; Florence Cabot; Robert W. Keane; Juan Pablo de Rivero Vaccari; Alfonso L. Sabater
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 818. doi:
Differences of the Endothelial Mosaic of Fuchs Endothelial Dystrophy examined by Non-Contact and Contact Corneal Specular Microscopes Open Access
Fernando Cesar Abib
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 819. doi:
Investigating the role of the fibrillar layer in Fuchs endothelial corneal dystrophy Open Access
Mario Matthaei; Thomas Clahsen; Christian Büttner; Sebastian Siebelmann; Ludwig M Heindl; Björn Bachmann; Claus Cursiefen; Agathe Hribek
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 820. doi:
Comparison of the protein composition between fresh and frozen acellular Descemet’s membranes Open Access
Viridiana Kocaba; Vidhya Venkatraman; Dawn Neo; Gary S L Peh; Jodhbir S Mehta
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 821. doi:
Effects of IGFBP-3 on Mitochondrial Fitness in Corneal Endothelial Cells Open Access
Melis Kabaalioğlu Güner; Whitney Stuard; Danielle M Robertson
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 822. doi:
3D environment and intraocular pressure increase corneal endothelial cell sodium-potassium pump activity. Open Access
Princia Anney; Mathieu Thériault; Stephanie Proulx
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 823. doi:
Efficacy of Neuropeptide Alpha-Melanocyte Stimulating Hormone (α-MSH) in Suppressing Corneal Edema Following Acute Injury Open Access
Hamid Alemi; Shudan Wang; Neha Deshpande; Tomas Blanco; Kunpeng Pang; Erdem Yuksel; Hayate Nakagawa; Rohan Bir Singh; Thomas Dohlman; Jia Yin; Ula V Jurkunas; Reza Dana
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 824. doi:
Examining the relationship between injector lumen diameter and exposed endothelial surface area and tissue conformation of DMEK tissue scrolls Open Access
Yong Kam; Gregory Schmidt; Mark A Greiner; Jennifer Ling; Christopher Sales
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 825. doi:
Deep neural network for the analysis of guttae via semi-supervised learning in a Fuchs endothelial corneal dystrophy mouse model Open Access
Takeru Nishikawa; Naoki Okumura; Kaito Narimoto; Shohei Yamada; Kengo Okamura; Ayaka Izumi; Noriko Koizumi
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 826. doi:
Proteomic analysis of TCF4 knock-out corneal endothelial cells derived from the patients with Fuchs endothelial corneal dystrophy Open Access
Tatsuya Nakagawa; Naoki Okumura; Naoya Hanada; Prema Padmanabhan; Sailaja Elchuri; Amit Chatterjee; Narayanan Janakiraman; Gajanan Sathe; Vivek Ghose; Theofilos Tourtas; Ursula Schlötzer-Schrehardt; Friedrich E Kruse; Noriko Koizumi
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 827. doi:
Development of a new xeno-free human corneal endothelial cells culture system based on Platelet Rich in Growth Factors. Open Access
Sergio Alonso-Alonso; Natalia Vázquez; Carlota Suarez-Barrio; Susana del Olmo Aguado; Manuel Chacon; Eva Garcia-Perez; Mairobi Persinal-Medina; José F. Alfonso; Belén Alfonso; Jesus Merayo-Lloves; Alvaro Meana
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 828. doi:
Biosynthetic corneal endothelial graft functions in a rabbit model of corneal endothelial damage Open Access
Hannah J Levis; Constandinos Carserides; Vito Romano; Rachel Williams
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 829. doi:
Impact of oxidative stress on the cytoskeleton and barrier integrity of the corneal endothelium Open Access
Anupama C; M. Y. Thanuja; Sudhir H Ranganath; Sangly P Srinivas
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 830. doi:
Mitochondrial ROS leads to lysosomal dysfunction and autophagy impairment in an animal model of Congenital Hereditary Endothelial Dystrophy Open Access
Raji Shyam; Diego G. Ogando; Moonjung Choi; Paloma Borrajo Liton; Joseph A Bonanno
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 831. doi:
A robust approach to assess cellular yield from simple non-cultured endothelial cells (SNEC) harvesting technique for corneal endothelial cell-injection therapy Open Access
Gary S L Peh; Khadijah Adnan; Dawn Neo; Hon Shing Ong; Jodhbir S Mehta
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 832. doi:
Loss of NQO1 generates genotoxic estrogen byproducts and causes increased female susceptibility to UVA in Fuchs dystrophy Open Access
Varun Kumar; Neha Deshpande; Hanna Hui; Muhammad Zahid; Eleanor G. Rogan; Ula V Jurkunas
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 833. doi:
Solubilized Ubiquinol Improves Reactive Oxygen Species Scavenging in Donor Corneal Endothelial Cells Open Access
Sanjib Saha; Youssef W. Naguib; Jessica M. Skeie; Timothy Acri; Kareem Ebeid; Somaya Abdel-rahman; Sandeep Kesh; Gregory Schmidt; Darryl Y. Nishimura; Mark A Greiner; Aliasger K. Salem
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 834. doi:
The Role of NQO1 in the Increased DNA Damage Response in Fuchs Endothelial Corneal Dystrophy Open Access
Alex Gauthier
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 835. doi:
Short-Term Effects on Corneal Endothelial Cell Density and Morphology After Deep Small Incision Lenticule Extraction (SMILE) Open Access
Simran Mangwani Mordani; Enrique O Graue-Hernandez; Alejandro Navas Perez; Arturo Ramirez Miranda
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 836. doi:
Effect of anti-inflammatory eye drops on cultured porcine corneal endothelial cell viability Open Access
Dominic F Hakim; Takako Noguchi; Anser A Abbas; Emma N Finburgh; Natalie A Afshari
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 837. doi:
Defective DNA Repair in Fuchs endothelial corneal dystrophy Open Access
Neha Deshpande; Geetha Melangath; Shivakumar Vasanth; Marianne Price; Francis Price; Ula V Jurkunas
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 838. doi:
Restoration of corneal clarity after transplantation of an engineered corneal endothelium: preliminary in vivo model Open Access
Judith Zavala; Maria Dolores Montalvo Parra; Denise Loya; Andres Bustamante Arias; Miguel Hernández; Sergio Guevara-Quintanilla; Salvador Garza; Marcelo Salan-Gomez; Jorge E Valdez
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 839. doi:
Evaluation of function-related corneal endothelial markers in TAZ deficient mice over time Open Access
Sangwan Park; Brian Leonard; Soohyun Kim; Michelle E Mccorkell; Christopher J Murphy; Vijaykrishna Raghunathan; Sara M Thomasy
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 840. doi:
Epithelial abrasion induces distinct changes in interaction of 2 ion channel proteins Pannexin1 and P2X7 in diabetic mice Open Access
Vickery E Trinkaus-Randall; Kristen L Segars; Celeste B Rich
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 841. doi:
Topical Recombinant Human Nerve Growth Factor Improves Outcomes in Murine Model of Neuropathic Corneal Pain Open Access
Brendan Kenyon; Deshea L Harris; Fangfang Qiu; Cecilia Chao; Yashar Seyed-Razavi; Pedram Hamrah
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 842. doi:
Validation of a novel single-use esthesiometer to test corneal sensitivity Open Access
Marta Sacchetti; Francesca Giovannetti; alice bruscolini; marco marenco; giulia firmani; antonio valerio chicca; alessandro lambiase
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 843. doi:
Differential Effects of Two Ocular Surface Injury Models on the Functional Properties of Regenerated Corneal Sensory Nerves Open Access
Evguenia Ivakhnitskaia; Tara Nguyen; Qiang Zhou; Joy Sarkar; Victor H Guaiquil; Harumitsu Hirata; Kuei Y. Tseng; Mark Rosenblatt
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 844. doi:
PRMT1 Enhances Corneal Epithelial Wound Healing Open Access
Peter Reinach; Qiongjie Cao; Dongsheng Yan
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 845. doi:
Epithelial IL-2 receptor expression and its effects on corneal nerves Open Access
Mary Ann Stepp; Sonali Pal Ghosh; Gauri Tadvalkar; Jehan Alam; Winston W-Y Kao; Vivien J Coulson-Thomas; Cintia S De Paiva
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 846. doi:
Wnt5a promotes diabetic corneal epithelial wound healing and limbal stem cell expression Open Access
Ruchi Shah; Tanya M Spektor; Vasu Punj; Sue Turjman; Sean Ghiam; Jiho Kim; Sasha Tolstoff; Cynthia Amador; Steven Takeshi Chun; Daniel J Weisenberger; Mehrnoosh Saghizadeh; Andrei A Kramerov; Alexander V Ljubimov
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 847. doi:
Role of AMP-activated protein kinase (AMPK) in corneal epithelial cells stimulated by fungi Open Access
Hongmin Zhang; Chun-mei Wang; Jingjing Wei; Wei Si; Juan Yue; Yanting Xie
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 848. doi:
CD147 contributes to maintain a nonkeratinized squamous epithelium in cornea Open Access
Pablo Argueso; Ashley M. Woodward; Marissa N. Feeley; Jamie Rinaldi
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 849. doi:
Thrombospondin is Up Regulated by Proteasome Inhibition Open Access
Fawzia Bardag-Gorce; Jeremy Stark; Daileen Cortez; imara Meepe; Carter Hoffman; Joan Oliva; Richard Hoft; Samuel French; Yutaka Niihara
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 850. doi:
Conditional Deletion of AP-2β in the Periocular Mesenchyme of Mice Promotes Corneal Conjunctivalization Open Access
Haydn Walker; Aftab Taiyab; Monica Akula; Trevor Williams; Judith A West-Mays
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 851. doi:
IGFBP-3 mediates mitochondrial homeostasis during hyperosmolar stress Open Access
Whitney Stuard; Danielle M Robertson
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 852. doi:
Expression of Apical-Basal Polarity Determinants during Corneal Epithelial Stratification and Maturation. Open Access
Anil Tiwari; Sudha Swamynathan; Gregory Campbell; Shivalingappa K Swamynathan
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 853. doi:
Regional Differences of Novel Limbal Palisade of Vogt Complex Parameters using En Face Optical Coherence Tomography in Healthy Subjects Open Access
Daniel Saukkonen; William Binotti; Anya de Leeuw; Betul Bayraktutar; M. Cuneyt Ozmen; Pedram Hamrah
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 854. doi:
Long-term Survival of Cultivated Oral Mucosal Epithelial Cell Sheets in post-COMET Patients Open Access
Yi-Jen Hsueh; Hung-Chi Chen; Hui-Kang David Ma
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 855. doi:
Matriptase Deletion: A Model of Dry Eye. Open Access
Linda D Hazlett; Denise Bessert; Sharon A McClellan; Mallika Somayajulu; Karin List
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 856. doi:
Toxicity of amphotericin B on corneal epithelial cells stored in Optisol-GS: corneal epithelial cell morphology and migration Open Access
Kohei Harada; Hideki Fukuoka; Yuriko Ban; Yulia Aziza; Hidetoshi Tanioka; Shigeru Kinoshita; Masafumi Uematsu; Takashi Kitaoka; Chie Sotozono
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 857. doi:
The Evaluation of Barrier Function in Ocular Surface Epithelium Response Mechanism via Toll-like Receptor 3 (TLR3) Open Access
Yulia Aziza; Yuriko Ban; Shigeru Kinoshita; Chie Sotozono
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 858. doi:
In vitro characterization of a novel in situ-forming semi-interpenetrating polymer network of crosslinked collagen and glycosaminoglycans for corneal defect repair Open Access
David C Mundy; Fang Chen; Peter Le; David Myung
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 859. doi:
Retrospective large-cohort evaluation of trans-epithelial phototherapeutic keratectomy (PTK) for recurrent corneal erosion syndrome (RCES) Open Access
Po Hsiang (Shawn) Yuan; Geoffrey Ching; Mukhtar Bizrah; Simon Holland
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 860. doi:
Single-Cell Transcriptomics Identifies Limbal Stem Cell Population, Differentiation Trajectory and Signature Markers in Human Corneal Limbus Open Access
De-Quan Li; Jinmiao Li; Sangbae Kim; Jongsu Choi; Fang Bian; Stephen C Pflugfelder; Rui Chen
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 861. doi:
Prospective evaluation of the safety and efficacy of Cultivated Oral Mucosal Epithelial Transplantation (COMET) for fornix reconstruction in cases of severe ocular surface disease Open Access
Seitaro Komai; Kojiro Imai; Takahiro Nakamura; Tsutomu Inatomi; Mayumi Ueta; Masahiro Go; Yasuko Kimura; Masanori Fukushima; Shigeru Kinoshita; Chie Sotozono
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 862. doi:
High mobility group box 1 mediated crosstalk between infected corneal epithelial cells and stromal keratocytes Open Access
Amrita Saha; Ashrafali Mohamed Ismail; Xiaohong Zhou; James Chodosh; Jaya Rajaiya
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 863. doi:
Conjunctival and Scleral Thicknesses with and without Conjunctival Ultraviolet Autofluorescence Open Access
Alyra Shaw; Pryntha Rajasingam; Brett A Davis; Michael J Collins
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 864. doi:
The battle of the Ephs in regulating miRNA boundaries in ocular anterior segmental epithelia Open Access
Nihal Kaplan; Wending Yang; Han Peng; Robert Lavker
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 865. doi:
Photoporation of the corneal epithelium with biocompatible poly-dopamine nanoparticles for the delivery of biologics Open Access
Mike Wels; Félix Sauvage; Koen Raemdonck; Dimitri Roels; Kevin Braeckmans; Stefaan De Smedt
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 866. doi:
Identification of Human Epithelial Cell Type by Analysis of Cell Function in Cultured Conjunctival Epithelium Open Access
Jeffrey Bair; Robin Hodges; Darlene A Dartt
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 867. doi:
Parallel genomic and proteomic profiling of miR-10b targets in human limbal epithelial cells Open Access
Adam Poe; DRIRH KHARE; Yizhou Wang; Alexander V Ljubimov; Jennifer Van Eyk; Mehrnoosh Saghizadeh
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 868. doi:
Mapping of label retaining cells and hyaluronan in the mouse cornea Open Access
Xiao Lin; Mingxia Sun; Kazadi N Mutoji; Vivien J Coulson-Thomas
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 869. doi:
Autophagy in the limbal epithelium during UV-induced stem cell damage Open Access
Thomas Volatier; Claus Cursiefen; Maria Notara
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 870. doi:
Efficacy and safety of induced pluripotent stem cell-derived corneal endothelial-like cell transplantation in rabbit animal model of corneal endothelial failure Open Access
Hun Lee; Ye Eun Han; Jimin Park; Sol Ah Han; Su Young Moon; Jae Yong Kim; Hungwon Tchah
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 871. doi:
Rheological and Proteomics Characterization of Thermoresponsive Hydrogel from Porcine Cornea Extracellular Matrix for Corneal Tissue Engineering Purposes Open Access
Ghasem Yazdanpanah; Yizhou Jiang; Sayena Jabbehdari; Khandaker Anwar; Xiang Shen; Seungwon An; Elmira Jalilian; Meisam Omidi; Mark Rosenblatt; Tolou Shokuhfar; Yayue Pan; Alexandra Naba; Ali R Djalilian
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 872. doi:
Generation of Three-dimensional Stem Cell Derived Eye Organoids with Corneal Features Open Access
Anne Zebitz Eriksen; Timothy A Blenkinsop
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 873. doi:
The effects of fibroblast growth factor-10 on primary corneal and lacrimal gland human epithelial cell cultures Open Access
Emma N Finburgh; Takako Noguchi; Anser A Abbas; Dominic F Hakim; Natalie A Afshari; Helen P Makarenkova
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 874. doi:
Characterization and application of a hydrogel derived from acellular porcine corneal stroma Open Access
Qiang Zhou; Victor H Guaiquil; Alejandro Escobar; Matthea Wong; Evguenia Ivakhnitskaia; Ghasem Yazdanpanah; Hongwu Jing; Michael Sun; Joy Sarkar; Yuncin Luo; Mark Rosenblatt
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 875. doi:
Identification Of Putative Limbal Stem Cells By Analyzing Label-Retaining Cells In H2B-GFP Mice Using Single-Cell RNA Sequencing Open Access
Hua Mei; Zhenwei Song; Di Wu; Brian Dong Chen
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 876. doi:
Mitochondrial and metabolic alterations in diabetic corneal epithelial cells Open Access
Natalia Mussi; Whitney Stuard; Melis Kabaalioğlu Güner; Danielle M Robertson
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 877. doi:
Novel En Face Optical Coherence Tomography Parameters for the Assessment of Palisades of Vogt Complex in Patients with Limbal Stem Cell Deficiency Open Access
William Binotti; Anya de Leeuw; Daniel Saukkonen; Betul Bayraktutar; M. Cuneyt Ozmen; Pedram Hamrah
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 878. doi:
CD103+ Dendritic Cells Suppress Th1 Alloimmunity by Modulating CD11b+ Antigen Presenting Cells via IL-10 Open Access
Tomas Blanco; Hayate Nakagawa; Hamid Alemi; Rohan Bir Singh; shuyan zhu; Yukako Taketani; Sonia Anchouche; Yihe Chen; Sunil Chauhan; Jia Yin; Reza Dana
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 879. doi:
Time-dependent serial changes of antigen-presenting cell subsets are distinct between the corneal sterile inflammation and allosensitization Open Access
Kyoung Woo Kim; Hyun Ju Lee; Hyeon Ji Kim; Mee Kum Kim
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 880. doi:
Corneal Nerves Modulate Angiogenesis via Secreted Neuropeptides Open Access
Jia Yin; shuyan zhu; Lingjia Liu; Kunpeng Pang
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 881. doi:
The Regulatory Effect of IFN-γ or IL-17A Primed Limbal Mesenchymal Stem Cells on Lymphocytes Immune Response Open Access
Noushin Zibandeh; Eda Kusan; Afsun Sahin
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 882. doi:
Effects of anti-inflammatory eye drops in cultured human corneal epithelial cells Open Access
Takako Noguchi; Ruti Sella; Yamit Cohen-Tayar; Jiagang Zhao; Rebecca Lian; Anser A Abbas; Emma N Finburgh; Dominic F Hakim; Natalie A Afshari
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 883. doi:
The effect of topical decorin on corneal immune cell dynamics after epithelial abrasion Open Access
Mengliang Wu; Laura Elizabeth Downie; Lisa J Hill; Holly R Chinnery
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 884. doi:
Effect of the rho-kinase inhibitor Netarsudil on established corneal neovascularization in a PAX-6 knockout mouse model Open Access
Timothy Janetos; Ting Liu; Pieter R Norden; Tsutomu Kume; Surendra Basti
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 885. doi:
CRISPR/Cas9-mediated gene-editing of TAPBP to alleviate antigenicity of human corneal-limbal epithelial cells Open Access
Giorgia Scapin; Sunil Chauhan
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 886. doi:
Ocular surface distribution of mast cells functionally contributes to asymmetrical angiogenic response Open Access
WonKyung Cho; Sharad Mittal; Elsayed Elbasiony; Sunil Chauhan
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 887. doi:
Galectin 8 impairs TLR4 signaling and dampens innate immune response to P. aeruginosa infection in mouse corneas Open Access
Noorjahan A Panjwani; Zhiyi Cao; Abdulraouf Ramadan
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 888. doi:
Repeatability and reliability of density and morphology measurements of corneal and conjunctival epithelial dendritic cells using in vivo confocal microscopy. Open Access
Ali Alghamdi; Zahra Tajbakhsh; Isabelle Jalbert; Fiona Stapleton; Blanka Golebiowski
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 889. doi:
Mast cells directly activate corneal allograft-primed T cells Open Access
Elsayed Elbasiony; Sharad Mittal; WonKyung Cho; Sunil Chauhan
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 890. doi:
Anti-inflammatory medication after corneal trauma or surgery to prevent subsequent late glaucoma. Open Access
Eleftherios I Paschalis; Chengxin Zhou; Fengyang Lei; Sarah Kim; Demetrios G. Vavvas; James Chodosh; Arto Urtti; George Papaliodis; Claes H Dohlman
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 891. doi:
Interactions between mesenchymal stem cells (MSCs) and trigeminal ganglion (TGs) improve neurite growth and elongation Open Access
Elmira Jalilian; Ilham Putra; Eitan Katz; Ghasem Yazdanpanah; Victor H Guaiquil; Xiang Shen; Khandaker Anwar; Seungwon An; Mark Rosenblatt; Ali R Djalilian
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 892. doi:
A pilot study to characterise the immune response in human Herpes Keratitis Open Access
Sana Arshad; Damien Hunter; Kirstie Bertram; Andrew JR White; Con Petsoglou; Anthony Cunningham; Nicole Ann Carnt
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 893. doi:
Epidermal Growth Factor Enhances Exosome-mediated Anti-angiogenic Signals between M1 Macrophages and Human Corneal Endothelial Cells Open Access
Soojin Lee; Kyoung Woo Kim
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 894. doi:
Sustained hyperglycemia impairs corneal re-epithelialization after alkaline injury through modulation of the ocular surface, systemic Immunity and intestinal microbiome Open Access
Yashan Bu; Yau Kei Chan; Amy CY Lo; Kendrick Co Shih
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 895. doi:
Genetic variability of lymphangiogenesis in Collaborative Cross mice: a powerful tool to identify novel endogenous regulators of lymphangiogenesis Open Access
Thomas Clahsen; Christian Büttner; Niloofar Hatami; Felix Nüst; Tim Gabriel; André Reis; Claus Cursiefen
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 896. doi:
Injury dependent angiogenic responses in the cornea Open Access
Wei Zhang; Karina Hadrian; Claus Cursiefen; Felix Bock
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 897. doi:
IFNγ+IL17+ effector T cells are the principal source of memory Th17 cells in dry eye disease Open Access
Nai-Wen Fan; Yihe Chen; Sunil Chauhan; Reza Dana
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 898. doi:
Cystathionine β-synthase as novel regulator of lymphangiogenesis Open Access
Niloofar Hatami; Christian Büttner; Felix Bock; Sara Simfors; André Reis; Claus Cursiefen; Thomas Clahsen
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 899. doi:
Aflibercept influences the immunocompetence of Dendritic Cells. Open Access
Jasmin J Weindler; Felix Bock; Matthias Hamdorf; Claus Cursiefen
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 900. doi:
Development of small molecule inhibitors against the corneal neovascularization via MMP14 Open Access
Kyuyeon Han; HYUN LEE; Dimitri T Azar
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 901. doi:
Topical nanoemulsion of a RUNX1 inhibitor for the treatment of corneal neovascularization Open Access
Santiago Delgado-Tirado; Lucia Gonzalez-Buendia; Miranda An; Jose M. Ruiz-Moreno; Leo A Kim; Joseph Arboleda-Velasquez
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 902. doi:
EFFICACY of CELL-BASED PLASMACYTOID DENDRITIC CELL THERAPY FOR CORNEAL WOUND HEALING Open Access
Arsia Jamali; Betul Bayraktutar; Deshea L Harris; Victor G. Sendra; Pedram Hamrah
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 903. doi:
Evaluation of in vivo murine modeling of Staphylococcus aureus bacterial keratitis Open Access
Tomas Meijome; Rachel Wozniak; Lyna Azzouz; Leslie M Niziol; Matthias Kriegel; Maria A Woodward
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 904. doi:
Distinct Plasmacytoid Dendritic Cell-T Cell Contacts in Draining Lymph Nodes Define T Cell Responses during Acute Herpes Simplex Virus Keratitis Open Access
Victor G. Sendra; Arsia Jamali; Brendan Kenyon; Deshea L Harris; Pedram Hamrah
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 905. doi:
The Impact of Donor Diabetes on Corneal Immune Cells and Corneal Transplant Survival Open Access
Hayate Nakagawa; Tomas Blanco; Thomas Dohlman; shuyan zhu; Hamid Alemi; Bruno-Adonai Gonzalez-Nolasco; Yihe Chen; Jia Yin; Reza Dana
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 906. doi:
Inhibition of corneal neovascularization with rAAV-anti-VEGF in mouse corneal injury models Open Access
Wenqi Su; shuo sun; Bo Tian; Yongwen Luo; Jihye Ko; Phillip W.L. Tai; Xiao Ke; Qiang zheng; Hua Yan; Haijiang Lin; Guangping Gao
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 907. doi:
Mesenchymal stem cells enhance suppressive function of T regulatory cells and promote corneal graft survival Open Access
Sharad Mittal; WonKyung Cho; Elsayed Elbasiony; Sunil Chauhan
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 908. doi:
Effect of sCD83 on macrophages in corneal high-risk transplantation Open Access
Alfrun Schönberg; Katrin Peckert-Maier; Andreas Wild; Dmytro Royzman; Gabriele Braun; Lena Stich; Claus Cursiefen; Alexander Steinkasserer; Felix Bock; Elisabeth Zinser
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 909. doi:
Up-Regulation of Multiple CD8+ T Cell Exhaustion Pathways is Associated to Recurrent Ocular Herpes Simplex Virus Type 1 Infection Open Access
Lbachir BenMohamed; Swayam Prakash; Ruchi Srivastava; Nisha Dhanushkodi; Pierre-Gregoire A Coulon
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 910. doi:
Long-term outcome of aflibercept subconjuctival treatment for chemical induced corneal neovascularization in the rabbit model Open Access
Ariel Gore; Tamar Kadar; Mayyan Cohen; Hila Gutman; Liat Cohen; Relli Gez; Shlomit Dachir; Vered Horwitz
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 911. doi:
Retinoid X receptor alpha (RXRa) mutant Pinkie and vitamin A deficient B6 mice develop similar spectrum of corneal inflammation Open Access
Jehan Alam; Zhiyuan Yu; Rinki Ratnapriya; Cintia S De Paiva; Stephen C Pflugfelder
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 912. doi:
Corneal Nerve Alterations of Neuropathic Corneal Pain Patients with Underlying Autoimmune Conditions: Comparative In Vivo Confocal Microscopy Study in Patients with and without Anti-Neuro... Open Access
Leyla Yavuz Saricay; Betul Bayraktutar; Vanessa Atocha; Pedram Hamrah
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 913. doi:
Nociceptors control innate responses to Pseudomonas aeruginosa Open Access
Mihaela G Gadjeva; Daisy Quellier; Jeffrey Lamb
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 914. doi:
Trigeminal ganglion neurons directly modulate leukocyte migration via chemotactic mediators Open Access
Sudan Puri; Brendan Kenyon; Victor G. Sendra; Fangfang Qiu; Yashar Seyed-Razavi; Pedram Hamrah
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 915. doi:
Dose dependent induction and kinetics of human beta-defensin 3 peptide expression after treatment with herbal compounds Open Access
Brian Leonard; Theint Aung; Melinda Quan; Allison Shannon; VijayKrishna Raghunathan; Sara M Thomasy; Christopher J Murphy
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 916. doi:
Regulatory T cells Modulate Th1 Alloimmune Response by Early Suppression of Graft-site Antigen Presenting Cells via TGF-β1 Open Access
Rohan Bir Singh; Tomas Blanco; Hayate Nakagawa; Hamid Alemi; Thomas Dohlman; Yihe Chen; Sunil Chauhan; Jia Yin; Reza Dana
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 917. doi:
Single-cell RNA-seq reveals a dynamic shift of engrafted peripheral macrophages in the CNS towards a microglia signature. Open Access
Fengyang Lei; Naiwen Cui; Chengxin Zhou; Yamei Cai; Claes H Dohlman; James Chodosh; Demetrios G. Vavvas; Huidan Zhang; David A Weitz; Eleftherios I Paschalis
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 918. doi:
Interleukin (IL)-27 regulates corneal immunopathology and viral clearance during herpes simplex virus-1 (HSV) infection Open Access
Ferrin Antony; Maninder Sandey; Amarjit MIshra; Amol Suryawanshi
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 919. doi:
Systemic anti-transgene T-cell immune response induced by subretinal AAV gene transfer can be inhibited by a simultaneous co-injection of peptides from the transgene product Open Access
Sylvain Fisson; Gaëlle A Chauveau; Julie Vendomele; Deniz Dalkara; Anne Galy
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 920. doi:
Variant in the TNFRl gene associated with response to topical anti-TNFα antibody fragment OCS-02 in patients with dry eye disease Open Access
Victor L Perez
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 921. doi:
Sensory nerve retraction and sympathetic nerve innervation are involved in the immunopathology of murine recurrent Herpes Stromal Keratitis (HSK) Open Access
Hongmin Yun; Xiao-Tang Yin; Patrick Stuart; Anthony St. Leger
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 922. doi:
Single Cell RNA-Sequencing Points to an Inter-relationship between Corneal Macrophages and Dendritic Cells Open Access
Sejiro Littleton; Chen Yu; Rose Mathew; Joan Kalnitsky; Daniel R Saban
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 923. doi:
Chitosan film adhesive for sutureless corneal surgery Open Access
Jackie Tan; Leslie John Ray Foster; Stephanie L Watson
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 924. doi:
Human corneal stromal stem cells express specific microRNAs with anti-inflammatory and anti-fibrotic activities: a novel mechanism to reduce corneal scarring Open Access
Gary Hin-Fai Yam; Tianbing Yang; Moira L Geary; Martha L Funderburgh; Yiqin Du; Vishal Jhanji
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 925. doi:
A glial point of view: investigating corneal Schwann cells in ex vivo murine organ and whole-eye cultures Open Access
Gwendolyn Schultz; Paola Bargagna-Mohan; Royce Mohan
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 926. doi:
Effect of S-Nitrosylation on post-mortem donor cornea endothelial health during hypothermic storage period Open Access
Ahmed Omar; Onkar Sawant; James Reynolds; Kayla Jones; Stephanie How; Lin Zhu; Daniel Daroszewski; Jonathan H Lass
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 927. doi:
Long-term tolerability profiling of BMP7+HGF overexpression on rabbit cornea in vivo Open Access
Rajiv R Mohan; Suneel Gupta; Nishant Rajiv Sinha; Lynn Martin; Nathan Hesemann; Sabeeh Kamil; Prashant R. Sinha; Praveen Balne; Ratnakar Tripathi; Shyam S Chaurasia
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 928. doi:
Basement membrane integrity maintains blood vessel networks in inflamed corneas Open Access
Felix Bock; Viet Nhat Hung Le; Manuel Koch; Raphael Reuten
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 929. doi:
Regulation of SARS-CoV2 viral entry-related proteins in human ocular surface epithelium Open Access
Yuzuru Sasamoto; Catherine Lee; Masahito Yoshihara; Gabrielle Martin; Bruce Ksander; Markus H Frank; Natasha Frank
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 930. doi:
Perlecan-associated defective epithelial basement membrane regeneration in rabbit corneas after fibrosis-inducing epithelial-stromal injury Open Access
Rodrigo Carlos De Oliveira; George Tye; Lycia Sampaio; Thomas Michael Shiju; Marcony R Santhiago; JodiRae DeDreu; A Sue Menko; Steven E Wilson
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 931. doi:
Cell-free liquid hydrogel sealant/filler restores long term corneal integrity and shape after perforating and non-perforating trauma in feline eyes Open Access
Alejandro Juarez; Christopher D. McTiernan; Mohamed Djallali; Marilyse Piché; Fiona Simpson; May Griffith; Isabelle Brunette
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 932. doi:
Assembly of epithelial basement membrane (EBM) in vitro in a 3D organotypic cornea model Open Access
Shiju Thomas; Rodrigo Carlos de Oliveira; Lycia Pedral Sampaio; Guilherme Simões Luz Hilgert; Steven E Wilson
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 933. doi:
Cellular effects of a demethylating agent on normal human corneal endothelial cells Open Access
Georgia Kaidonis; Peipei Pan; Daniel J Weisenberger; Gangning Liang; David G Hwang; Ula V Jurkunas; Yu Tian; Matilda F Chan
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 934. doi:
ECM stiffness regulates the myofibroblastic differentiation of cultured primary keratocytes via subcellular changes in contractility and focal adhesion assembly. Open Access
Daniel Maruri; Miguel Miron-Mendoza; David Schmidtke; Matthew Petroll; Victor Varner
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 935. doi:
Topical Insulin - Utility and results in refractory Neurotrophic Keratopathy in stages 2 and 3 Open Access
Ricardo Machado Soares; Carlos Arêde; Joana Fernandes; Catarina Ferreira; Joaquim Sequeira
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 936. doi:
Collagen Expression in mini Ossabaw pigs Cornea with Type II Diabetes Open Access
Nishant Rajiv Sinha; Alexandria Caroline Hofmann; Praveen Balne; Rajiv R Mohan; Shyam S Chaurasia
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 937. doi:
Gellan Hydrogel Eyedrop Promotes Wound Healing and Prevents Fibrosis of Cornea by Preferentially Absorbing Pro-Fibrotic Proteins Open Access
Rachel Caroline Vincent; Richard J.A. Moakes; Gibran Farook Butt; Anthony D. Metcalfe; Richard L. Williams; Graham R Wallace; Ann Logan; Saaeha Rauz; Liam M Grover
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 938. doi:
Effects of mustard gas exposure to the corneal basement membrane and epithelial-stromal attachment to human cornea ex vivo Open Access
Ratnakar Tripathi; Nishant Rajiv Sinha; Praveen Balne; Suneel Gupta; Nathan Hesemann; Jason T Rodier; Prashant R. Sinha; Shyam S Chaurasia; Rajiv R Mohan
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 939. doi:
A novel, easy-to-use hydrogel sealant (OcuPairTM) for temporary corneal repair Open Access
Siva Pramodh Kambhampati; Hui Lin; Rishi Sharma; Santiago Appiani; Dan Saragnese; Samuel C Yiu; Jeffrey Cleland; Kannan Rangaramanujam
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 940. doi:
Evaluation of pirfenidone and pirfenidone-loaded liposomes for treating chemical corneal injury Open Access
Isaac Vidal Paredes; Carlos Daniel Diaz Palomera; Jose Navarro Partida; Arturo Santos; Juan Armendariz Borunda
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 941. doi:
Mechanism associated with acrolein’s toxicity to the cornea in vitro Open Access
Suneel Gupta; Nishant Rajiv Sinha; Praveen Balne; Ratnakar Tripathi; Nathan Hesemann; Prashant R. Sinha; Rajiv R Mohan
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 942. doi:
Vimentin as Regulator of Spreading and Migration of Corneal Fibroblasts in 3D Collagen Matrices Open Access
Miguel Miron Mendoza; Kara Poole; Hajar Hassaniardekani; Matthew Petroll
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 943. doi:
Cellular and molecular changes in human corneal fibroblasts following hydrogen sulfide exposure in vitro Open Access
Praveen Kumar Balne; Nishant Rajiv Sinha; Alexandria Caroline Hofmann; Ratnakar Tripathi; Suneel Gupta; Prashant R. Sinha; Rajiv R Mohan
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 944. doi:
A corneal tissue opacity model for the evaluation of corneal wound healing technologies Open Access
Peter Le; David Myung
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 945. doi:
A multifactorial blast injury model induces consistent and controllable damage in ex vivo and in vivo animal studies Open Access
R Glenn Hepfer; Peng Chen; Hai Yao
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 946. doi:
Bio-orthogonally Crosslinked Matrix Therapies for Corneal Defect Repair Open Access
David Myung; Fang Chen; Gabriella Fernandes-Cunha; Peter Le; Sarah Hull; Sarah Heilshorn
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 947. doi:
Supramolecular host-guest hyaluronic acid hydrogels for corneal endothelial cell delivery and epithelial wound healing Open Access
Caitlin M Logan; Gabriella Fernandes-Cunha; Sang Hoon Jung; Peter Le; David C Mundy; Mungu Kim; Geon-Hui Lee; Sei Kwang Hahn; David Myung
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 948. doi:
Freeze-dried versus cryopreserved amniotic membranes in corneal ulcers treated by overlay transplantation: a case-control study. Open Access
benjamin MEMMI; Loic LEVEZIEL; Juliette KNOERI; Amelie LECLERE; Marie-Claire DESPIAUX; Nacim Bouheraoua; Jean-Philippe NORDMANN; Christophe Baudouin; Vincent Borderie
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 949. doi:
3D-printed ABCB5-positive stem cells for treating bilateral limbal stem cell deficiency Open Access
Catherine Lee; Wonhye Lee; Jennifer Kunes; Yuzuru Sasamoto; Bruce Ksander; Markus H Frank; Seung-Schik Yoo; Natasha Frank
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 950. doi:
Prospects of lower lip mucosa stem cells in corneal restoration Open Access
Kirill Zhurenkov; Olga Aleksandrova; Ilya Gavrilyik; Natalya Yartseva; Svetlana Aleksandrova; Tatyana Mashel; Julia Khorolskaya; Daria Perepletchikova; Miralda Blinova
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 951. doi:
Single-cell RNA-seq analysis of human cornea and corneal organoid Open Access
George Maiti; Karl J Wahlin; James W Foster; Shukti Chakravarti
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 952. doi:
Pluripotent Stem Cell-derived Corneal Endothelial Cells for Donor-Free Keratoplasty Open Access
Muhammad Ali; Shahid Y Khan; John Gottsch; Eric Hutchinson; Aisha Khan; S. Amer Riazuddin
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 953. doi:
Comparison of Pre-operative Measured to Post-operative Refractive Astigmatism in Pseudophakes Open Access
Shavini Athukorala; Neal Kansara; Tara O'Rourke; Ingrid U Scott; Seth Pantanelli
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 954. doi:
Nittany-AK Calculator: A Novel Femtosecond Laser-assisted Keratotomy Nomogram for the Management of Corneal Astigmatism During Cataract Surgery Open Access
Catherine Seeger; Neal Kansara; Ashley Sun; Amy Longenecker; Brett Ernst; Gautam Mishra; Ingrid U Scott; Seth Pantanelli
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 955. doi:
Tear Neuromediator and Corneal Denervation following Small Incision Lenticule Extraction (SMILE) Open Access
Yu-Chi Liu; Molly Tzu-Yu Lin; Jodhbir S Mehta
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 956. doi:
Flap cut design for a new femtosecond laser for tissue-bridge-free corneal refractive surgery Open Access
Hong Fu; Nima Khatibzadeh; James Hill; Deepali Mehta-Hurt; Andrew Voorhees; Li Bing; Li Chen; Mohammad Rahaman; Cynthia Villanueva; Harvey liu; Paul Gray; Alisyn Facemire
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 957. doi:
Evaluating Iris Registration on a Femtosecond Laser for Refractive Corneal Lenticule Extraction Treatment Open Access
Li Chen; Andrew Voorhees; Li Bing; Hong Fu
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 958. doi:
Refraction vs. Keratometry Comparisons After Wavefront-Guided LASIK and Wavefront-Guided Photorefractive Keratectomy Open Access
Ying Wang; Cheryl McKinnon; Sanjeev Kasthurirangan
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 959. doi:
Confidence Intervals for Assessing Ectatic Changes Post-Crosslinking Using the ABCD Grading System Open Access
Hyun Soo Jang; Michael W Belin; Emilio Torres-Netto; Mark Borgstrom; Francesca Gilardoni; Hormoz Abdshahzadeh; Farhad Hafezi; Elias Flockerzi; Berthold Seitz
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 960. doi:
Full Field Tissue Ablation Profilometer with Submicron Precision Open Access
Alexander Vankov
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 961. doi:
Graft Survival after Penetrating Keratoplasty in Patients with History of Incisional Glaucoma Surgery Open Access
Sarah Marie Stuccio; Aakriti Garg Shukla; Wesam Shamseldin Shalaby; Eric J Shiuey; Zeba Almas Syed
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 962. doi:
Impact of Carrier Graft Thickness on Intraoperative Aqueous Leak after Boston Keratoprosthesis Implantation Open Access
Michael Moussa; Prateek Agarwal; Rony R Sayegh
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 963. doi:
Outcomes of simultaneous Descemet Stripping Automated Endothelial Keratoplasty (DSAEK) and intraocular lens exchange surgery Open Access
Abdelhalim Awidi; Yassine Daoud
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 964. doi:
Quality of life outcomes and prognostic factors one year after corneal transplantation: a nationwide cohort study Open Access
Ruth M A Van Nispen; Eline Vreijsen; Date van der Meij; Ellen Elsman; Rudy Nuijts; Ger H.M.B. van Rens
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 965. doi:
Longterm outcomes of Ahmed glaucoma valve (AGV) and Baerveldt glaucoma implant (BGI) in patients with Boston Keratoprosthesis type I (K-Pro) Open Access
Joseph Hakim; Dominique Geoffrion; Mona Harissi-Dagher
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 966. doi:
Topical ocular TRPV1 antagonist SAF312 was well tolerated and effectively reduced pain after photorefractive keratectomy (PRK) Open Access
Kalliopi Stasi; Vance Thompson; Majid Moshirfar; Thomas Clinch; Stephen Scoper; Steven Linn; Avery McIntosh; Yifang Li; Matt Eaton; Michela Montecchi Palmer; Sameena Haque; Michael Ferriere
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 967. doi:
Impact of cataract surgery on donor cornea suitability: an intra-individual retrospective audit Open Access
Andrew Muthurajah; Christopher Hodge; Con Petsoglou; Pierre Georges; Jane Treloggen; Gerard Sutton; Meidong Zhu
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 968. doi:
Assessing the Severity of Fuchs Endothelial Corneal Dystrophy by using Scheimpflug Tomography Open Access
Sanjay V Patel; Emily J Treichel; Keith H Baratz
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 969. doi:
Epidemiological profile of corneal transplant surgeries at Londrina Eye Hospital (HOFTALON), Brazil Open Access
Isabela Vale; Rafael Balestreri Trevisol; Ivan Luis Idalgo de Oliveira; Tiemi Matsuo; Erika Hoyama
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 970. doi:
Improving Refractive Outcomes in Patients with Keratoconus Treated with Superior-Masked Topography-Guided Photorefractive Keratectomy Open Access
Aditya Gill; Steven Greenstein
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 971. doi:
Visual Outcomes and Complications of Corneal Transplant With and Without Previous Glaucoma Surgery Open Access
Adnan Alawami; Henry Liu; Irfan Kherani; Fargol Mostofian; Setareh Ziai; George Mintsioulis; Kashif Baig
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 972. doi:
Factors associated with central corneal thickness changes after crosslinking combined with photorefractive keratectomy Open Access
Lacey Haines; Olivera Kralj; Sebastian Marschall; Ahmed Gawish; Paul Fieguth; Neera Singal; Hall Chew; David Rootman; Allan Slomovic; Wendy Hatch; Kostadinka K Bizheva; Luigina Sorbara
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 973. doi:
Corneal Crosslinking to Regress Pathological Corneal Neovascularization Before High-Risk Keratoplasty Open Access
Deniz Hos; Friederike Schaub; Yanhong Hou; Wei Zhang; Felix Bock; Claus Cursiefen
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 974. doi:
Optimising outcomes for cataract surgery in ocular mucous membrane pemphigoid Open Access
Nada Alfahad; Peter Nightingale; Apostolos Lazaridis; Mohammad Ahmad; Natraj Poonit; Saaeha Rauz
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 975. doi:
Readability Analysis of Laser Eye Surgery (LASIK) Online Patient Educational Material. Open Access
Erin Flynn; Haig Pakhchanian; Rahul Raiker; Craig Geist
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 976. doi:
Determining the Utility of Epithelial Thickness Mapping in Refractive Surgery Evaluations Open Access
James Randleman; Lara Asroui; William J. Dupps
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 977. doi:
A novel device for descemetorhexis creation: 3D Printed Prototype Design and Ex Vivo Evaluation Open Access
David Buickians; Michael Mbagwu; Charles C. Lin; David Myung
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 978. doi:
Modification of an eye bank pre-loaded DMEK graft preparation protocol to accommodate “flat” grafts Open Access
Megan M.W. Straiko; Tucker Hikes; Philip K Dye; Khoa D. Tran; Mark A Terry
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 979. doi:
Ten Year Experience of Optical Keratoplasty in Mexican Children Open Access
Norma Morales; Alejandro Navas; Lucero Pedro Aguilar; Arturo Ramirez Miranda; Enrique O Graue-Hernandez
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 980. doi:
Keratoconus-like Changes After Descemet Membrane Endothelial Keratoplasty in Patients with Fuchs' Dystrophy Open Access
Jeffrey Tapley; Alex Bauer; Michael Straiko; Mark A Terry
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 981. doi:
Treatment Decentration in Small Incision Lenticule Extraction (SMILE) Open Access
Lara Asroui; William J. Dupps; James Randleman
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 982. doi:
3 year outcomes of corneal wavefront guided PRK and simultaneous accelerated crosslinking in keratoconus Open Access
Enrique O Graue-Hernandez; Eduardo Gonzalez Lubcke; Jesus Cabral-Macías; Denisse Pinkus; Arturo Ramirez Miranda; Alejandro Lichtinger-Dondish; Alejandro Navas
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 983. doi:
Tear film cytokine profiles of Boston keratoprosthesis patients with and without glaucoma Open Access
Dominique Geoffrion; Marie-Claude Robert; Adriana Di Polo; Robert K Koenekoop; Younes Agoumi; Mona Harissi-Dagher
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 984. doi:
Descemet Membrane Endothelial Keratoplasty (DMEK) in vascularized high-risk eyes Open Access
Takahiko Hayashi; Wei Zhang; Deniz Hos; Silvia Schrittenlocher; Viet Nhat Hung Le; Sebastian Siebelmann; Mario Matthaei; Björn Bachmann; Felix Bock; Claus Cursiefen
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 985. doi:
Refractive Outcomes of Superficial Keratectomy for Salzmann Nodular Degeneration Open Access
Emily Witsberger; Leo Maguire; Sanjay V Patel
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 986. doi:
The Effects of Donor-Recipient Age and Sex Compatibility in the Outcomes of Anterior Lamellar Keratoplasties Open Access
Hon Shing Ong; Nathalie Chiam; Hla Myint Htoon; Anshu Arundhati; Jodhbir S Mehta
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 987. doi:
Descemet stripping endothelial keratoplasty: 15-year outcomes Open Access
Marianne Price; Francis Price
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 988. doi:
The diverse angiogenic effect of IL6-family cytokines on vascular endothelial cells and the modulatory influence of STAT3 signaling Open Access
Julian Rapp; Rhena Klar; Julian Wolf; Oliver Gorka; Ralph Fritsch; Olaf Groß; Clemens Lange; Hansjürgen Agostini; Gunther R Schlunck; Felicitas Bucher
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 989. doi:
An investigation of ocular surface intracellular cytokines in asymptomatic versus symptomatic soft contact lens wearers using a novel mass cytometry method. Open Access
Rachel Cant
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 990. doi:
Peptide Inhibitors of MARCKS Reverse Endotoxin Induced Uveitis in Rats Open Access
Tara Madeleine Stonex; Kenneth Adler; Beth Salmon; Brian C Gilger
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 991. doi:
OCU200 (transferrin-tumstatin fusion protein): A potential therapeutic for DME, DR, and wet-AMD Open Access
Arun K Upadhyay; Rasappa Arumugham; Pratap Naha; Dinesh Singh
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 992. doi:
bFGF alleviated dry eye disease by modulating inflammatory response and promoting healing process both in vitro and in vivo Open Access
YINGLUO XIONG; Bo Yang; Tao Jiang; Chenghao Xiong; Qi Xue; Haicai Li; Haizhou Fang; Ge Zhang; Malcom Ngiam
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 993. doi:
Prevention of experimental autoimmune uveitis by intravitreal AAV-EqIL-10 Open Access
Elizabeth Crabtree; Brian C Gilger; Matthew Hirsch; Jacquelyn Bower; Sara Smith; Beth Salmon; Liujiang Song
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 994. doi:
Sensitivity of a combined OCT index in glaucomatous eyes Open Access
Jordan Wilson; Thomas Callan; Sophia Yu; Mary K Durbin; Ian P Conner; Robert Chang; Tin Aung; Gary C Lee
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 995. doi:
Evaluation of an OCT B-scan of interest tool in glaucomatous eyes Open Access
Gary C Lee; Katherine Makedonsky; Laura Tracewell; Sophia Yu; Mary K Durbin; Noelleisha Graves; Charles Wu; Iryna Falkenstein; Todd Severin; Thomas Callan
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 996. doi:
Evaluation of machine learning algorithms for prediction of trabeculectomy outcomes Open Access
Ahmed Amer Zanabli; Hasan Ul Banna; Brian McMillan; Maria Lehmann; Sumeet Gupta; Joel R Palko
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 997. doi:
Predicting High Impact Ophthalmology Articles Using Machine Learning and Natural Language Processing Open Access
Yash Karandikar; Sophia Y Wang
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 998. doi:
AI estimation of the non-pathological loss rate for the waist of the nerve fiber layer in the optic nerve head Open Access
Konstancija Kisonaite; Zhaohua Yu; Camilla Sandberg Melin; Gabriel Carrizo; Chunliang Wang; Per G Soderberg
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 999. doi:
Intervisit specificity of a combined retinal ganglion cell index in glaucoma Open Access
David Christian Richter; Thomas Callan; Sophia Yu; Mary K Durbin; Ian P Conner; Robert Chang; Tin Aung; Gary C Lee
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 1000. doi:
Page 1 of 4
Copyright © 2025 Association for Research in Vision and Ophthalmology.
×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×
This site uses cookies. By continuing to use our website, you are agreeing to our privacy policy.Accept