Volume 64 Issue 13 | IOVS

Anatomy and Pathology/Oncology

Optical Density Ratio of Subretinal Fluid in Choroidal Melanomas Versus Choroidal Naevi Assessed by Optical Coherence Tomography Open Access

PDF

Zachary Mahoun; Denis Malaise; Livia Lumbroso-Le Rouic; Christine Levy-Gabriel; Nathalie Cassoux; Alexandre Matet

Tags: malignant melanoma of choroid, nevus of choroid, optical coherence tomography, optics, melanoma

Investigative Ophthalmology & Visual Science October 2023, Vol.64, 1. doi:https://doi.org/10.1167/iovs.64.13.1

Refractive Status and Biometric Characteristics of Children With Familial Exudative Vitreoretinopathy Open Access

PDF

Yarou Hu; Zixin Fan; Xinyu Zhao; Victor S. M. C. Correa; Zhenquan Wu; Xiaofeng Lu; Xianlu Zeng; Laijiao Chen; Zhen Yu; Lei Zheng; Jicang He; Guoming Zhang

Tags: biometry, familial exudative vitreoretinopathies, child

Investigative Ophthalmology & Visual Science October 2023, Vol.64, 27. doi:https://doi.org/10.1167/iovs.64.13.27

Release of Cell-Free Tumor DNA in the Plasma of Uveal Melanoma Patients Under Radiotherapy Open Access

PDF

Viktoria Kim; Maja Guberina; Nikolaos E. Bechrakis; Dietmar R. Lohmann; Michael Zeschnigk; Claudia H. D. Le Guin

Tags: circulating tumor dna, plasma, radiation therapy, uveal melanoma, neoplasms

Investigative Ophthalmology & Visual Science October 2023, Vol.64, 35. doi:https://doi.org/10.1167/iovs.64.13.35

Proteopathy Linked to Exon-Skipping Isoform of RGR-Opsin Contributes to the Pathogenesis of Age-Related Macular Degeneration Open Access

PDF

Chi Ren; Haoran Cui; Xuan Bao; Lvzhen Huang; Shikun He; Henry K. W. Fong; Mingwei Zhao

Tags: age-related macular degeneration, exons, mice, opsin, pathogenesis

Investigative Ophthalmology & Visual Science October 2023, Vol.64, 41. doi:https://doi.org/10.1167/iovs.64.13.41

Tumor Profiles of Late Presentation Uveal Ring Melanoma With Novel Characteristics – A Case Series Open Access

PDF

Joevy Z. Lim; Alexandra Z. Crawford; Charles N. J. McGhee

Tags: melanoma, neoplasms, uvea, uveal melanoma, enucleation procedure

Investigative Ophthalmology & Visual Science October 2023, Vol.64, 44. doi:https://doi.org/10.1167/iovs.64.13.44

Biochemistry and Molecular Biology

Investigation of Inter- and Intra-Day Variability of Tear Fluid Regarding Flow Rate, Protein Concentration as well as Protein Composition Open Access

PDF

Annika Guntermann; Oluwaseun Fatoba; Marc Kronenberg; Sabrina Reinehr; Pia Grotegut; Marc Schargus; Teresa Tsai; Svetlana Ivanova; Bettina Serschnitzki; Nina Kumowski; Christoph Maier; Katrin Marcus; H. Burkhard Dick; Stephanie C. Joachim; Caroline May

Tags: mass or substance concentration per volume, proteins, unit of flow rate

Investigative Ophthalmology & Visual Science October 2023, Vol.64, 13. doi:https://doi.org/10.1167/iovs.64.13.13

Evaluation of Ocular and Systemic Oxidative Stress Markers in Ocular Rosacea Patients Open Access

PDF

Nilufer Yesilirmak; Neslihan Bukan; Busra Kurt; Sema Yuzbasioglu; Min Zhao; Daniela Rodrigues-Braz; Akin Aktas; Francine Behar-Cohen; Jean-Louis Bourges

Tags: ocular rosacea, oxidative stress, rosacea

Investigative Ophthalmology & Visual Science October 2023, Vol.64, 22. doi:https://doi.org/10.1167/iovs.64.13.22

Clinical and Epidemiologic Research

Choroidal Changes After Anti-VEGF Therapy in AMD Eyes With Different Types of Macular Neovascularization Using Swept-Source OCT Angiography Open Access

PDF

Mengxi Shen; Hao Zhou; Jie Lu; Jianqing Li; Xiaoshuang Jiang; Omer Trivizki; Rita Laiginhas; Jeremy Liu; Qinqin Zhang; Luis de Sisternes; William J. Feuer; Robert O'Brien; Giovanni Gregori; Ruikang K. Wang; Philip J. Rosenfeld

Tags: angiogram, anti-vascular endothelial growth factor therapy, eye, macular neovascularization, cortical blindness

Investigative Ophthalmology & Visual Science October 2023, Vol.64, 16. doi:https://doi.org/10.1167/iovs.64.13.16

Ultrasound Assessment of Gaze-induced Posterior Eyewall Deformation in Highly Myopic Eyes Open Access

PDF

Kai Xiong Cheong; Shen Yi Lim; Yee Shan Dan; Ronald H. Silverman; Stanley Chang; Lawrence A. Yannuzzi; K. Bailey Freund; Kazuyo Ito; Quan V. Hoang

Tags: eye, gaze, myopia, staphyloma, ultrasonography

Investigative Ophthalmology & Visual Science October 2023, Vol.64, 38. doi:https://doi.org/10.1167/iovs.64.13.38

Unsupervised Learning Based on Meibography Enables Subtyping of Dry Eye Disease and Reveals Ocular Surface Features Open Access

PDF

Siyan Li; Yiyi Wang; Chunyu Yu; Qiyuan Li; Pingjun Chang; Dandan Wang; Zhangliang Li; Yinying Zhao; Hongfang Zhang; Ning Tang; Weichen Guan; Yana Fu; Yun-e Zhao

Tags: dry eye syndromes, learning, ocular surfaces

Investigative Ophthalmology & Visual Science October 2023, Vol.64, 43. doi:https://doi.org/10.1167/iovs.64.13.43

Worldwide Incidence of Ocular Melanoma and Correlation With Pigmentation-Related Risk Factors Open Access

PDF

Mike Wu; Serdar Yavuzyiğitoğlu; Erwin Brosens; Wishal D. Ramdas; Emine Kiliç; on behalf of the Rotterdam Ocular Melanoma Study Group (ROMS)

Tags: eye melanomas, incidence, pigmentation, risk factors, single nucleotide polymorphism

Investigative Ophthalmology & Visual Science October 2023, Vol.64, 45. doi:https://doi.org/10.1167/iovs.64.13.45

Cornea

Single-Cell Transcriptomics Reveals Cellular Heterogeneity and Complex Cell–Cell Communication Networks in the Mouse Cornea Open Access

PDF

Yueh-Feng Wu; Nai-Wen Chang; Li-An Chu; Hsin-Yu Liu; Yu-Xian Zhou; Yun-Lin Pai; Yu-Sheng Yu; Chen-Hsiang Kuan; Yu-Ching Wu; Sung-Jan Lin; Hsin-Yuan Tan

Tags: cell communication, cornea, heterogeneity, mice, rna, small cytoplasmic

Investigative Ophthalmology & Visual Science October 2023, Vol.64, 5. doi:https://doi.org/10.1167/iovs.64.13.5

Keratocyte-Derived Myofibroblasts: Functional Differences With Their Fibroblast Precursors Open Access

PDF

Ana C. Acosta; Hadi Joud; Mei Sun; Marcel Y. Avila; Curtis E. Margo; Edgar M. Espana

Tags: collagen, fibroblasts, keratocytes, myofibroblasts, cornea

Investigative Ophthalmology & Visual Science October 2023, Vol.64, 9. doi:https://doi.org/10.1167/iovs.64.13.9

Use of Nanoindentation in Determination of Regional Biomechanical Properties of Rabbit Cornea After UVA Cross-Linking Open Access

PDF

Xiaobo Zheng; Yue Xin; Chong Wang; Yiwen Fan; Peng Yang; Lingqiao Li; Danping Yin; Erchi Zhang; Yuxin Hong; Han Bao; Junjie Wang; Fangjun Bao; Weiwei Zhang; Shihao Chen; Ahmed Elsheikh; Michael Swain

Tags: cornea, corneal collagen cross-linking, cross-linking, oryctolagus cuniculus, ultraviolet a radiation

Investigative Ophthalmology & Visual Science October 2023, Vol.64, 26. doi:https://doi.org/10.1167/iovs.64.13.26

Adipose Mesenchymal Stem Cell-Derived Exosomes Promote the Regeneration of Corneal Endothelium Through Ameliorating Senescence Open Access

PDF

Yunkyoung Ryu; Jin Sun Hwang; Kyung Bo Noh; Se Hie Park; Je Hyun Seo; Young Joo Shin

Tags: ambulatory surgery center, exosomes, micrornas, aging, corneal endothelium

Investigative Ophthalmology & Visual Science October 2023, Vol.64, 29. doi:https://doi.org/10.1167/iovs.64.13.29

Molecular and Phenotypic Characterization of Ocular Methicillin-Resistant Staphylococcus epidermidis Isolates in Taiwan Open Access

PDF

Yin-Hsi Chang; Yhu-Chering Huang; Hung-Chi Chen; David H. K. Ma; Lung-Kun Yeh; Kuo-Hsuan Hung; Ching-Hsi Hsiao

Tags: biofilms, conjunctiva, disease susceptibility, eye infections, methicillin

Investigative Ophthalmology & Visual Science October 2023, Vol.64, 33. doi:https://doi.org/10.1167/iovs.64.13.33

Blocking Mitochondrial Pyruvate Transport Alters Corneal Myofibroblast Phenotype: A New Target for Treating Fibrosis Open Access

PDF

Kye-Im Jeon; Ankita Kumar; Christine L. Callan; Margaret DeMagistris; Scott MacRae; Keith Nehrke; Krystel R. Huxlin

Tags: cornea, fibrosis, mitochondria, myofibroblasts, phenotype

Investigative Ophthalmology & Visual Science October 2023, Vol.64, 36. doi:https://doi.org/10.1167/iovs.64.13.36

Characterization of the Limbal Epithelial Stem Cell Niche Open Access

PDF

Isabel Y. Moreno; Arian Parsaie; Tarsis F. Gesteira; Vivien J. Coulson-Thomas

Tags: cornea, epithelial stem cells, genes, immunohistochemistry, proteins

Investigative Ophthalmology & Visual Science October 2023, Vol.64, 48. doi:https://doi.org/10.1167/iovs.64.13.48

Eye Movements, Strabismus, Amblyopia and Neuro-ophthalmology

The Suppressive Basis of Ocular Dominance Changes Induced by Short-Term Monocular Deprivation in Normal and Amblyopic Adults Open Access

PDF

Ling Gong; Alexandre Reynaud; Robert F. Hess; Jiawei Zhou

Tags: adult, amblyopia, contrast sensitivity, eye, ocular dominance

Investigative Ophthalmology & Visual Science October 2023, Vol.64, 2. doi:https://doi.org/10.1167/iovs.64.13.2

Altered Eye Movements During Reading With Simulated Central and Peripheral Visual Field Defects Open Access

PDF

Haojue Yu; MiYoung Kwon

Tags: eye movement, reading (activity), saccades, scotoma, scotoma, central

Investigative Ophthalmology & Visual Science October 2023, Vol.64, 21. doi:https://doi.org/10.1167/iovs.64.13.21

Deficits of Visual Cortex Function in Acute Acquired Concomitant Esotropia Patients Open Access

PDF

Yan Hu; Shenjiang Wang; Lianqun Wu; Sida Xi; Wen Wen; Chen Zhao

Tags: esotropia, visual cortex, signs and symptoms

Investigative Ophthalmology & Visual Science October 2023, Vol.64, 46. doi:https://doi.org/10.1167/iovs.64.13.46

Genetics

Variants in the WDR45 Gene Within the OPA-2 Locus Associate With Isolated X-Linked Optic Atrophy Open Access

PDF

Inbal Gazit; Idan Hecht; Chen Weiner; Alina Kotlyar; Zina Almer; Erez Bakshi; Lior Or; Hadas Volkov; Barak Feldman; Idit Maharshak; Marina Michelson; Nitza Goldenberg-Cohen; Eran Pras

Tags: family, genes, optic atrophy, x-linked inheritance

Investigative Ophthalmology & Visual Science October 2023, Vol.64, 17. doi:https://doi.org/10.1167/iovs.64.13.17

A Slc38a8 Mouse Model of FHONDA Syndrome Faithfully Recapitulates the Visual Deficits of Albinism Without Pigmentation Defects Open Access

PDF

Ana Guardia; Almudena Fernández; Davide Seruggia; Virginie Chotard; Carla Sánchez-Castillo; Oksana Kutsyr; Xavier Sánchez-Sáez; Esther Zurita; Marta Cantero; Alexandra Rebsam; Nicolás Cuenca; Lluís Montoliu

Tags: albinism, mice, pigmentation, syndrome, homozygote

Investigative Ophthalmology & Visual Science October 2023, Vol.64, 32. doi:https://doi.org/10.1167/iovs.64.13.32

Influence of Genetic Polymorphisms on the Short-Term Response to Ranibizumab in Patients With Neovascular Age-Related Macular Degeneration Open Access

PDF

Laura García-Quintanilla; Pablo Almuiña-Varela; Olalla Maroñas; Almudena Gil-Rodriguez; María José Rodríguez-Cid; María Gil-Martinez; Maximino J. Abraldes; Francisco Gómez-Ulla de Irazazabal; Miguel González-Barcia; Cristina Mondelo-Garcia; Raquel Cruz; Ana Estany-Gestal; Maribel Fernández-Rodríguez; Anxo Fernández-Ferreiro

Tags: exudative age-related macular degeneration, pharmacogenetics, polymorphism, ranibizumab

Investigative Ophthalmology & Visual Science October 2023, Vol.64, 34. doi:https://doi.org/10.1167/iovs.64.13.34

Glaucoma

Investigating the Impact of Sun/UV Protection and Ease of Skin Tanning on the Risk of Pseudoexfoliation Glaucoma: A Mendelian Randomization Study Open Access

PDF

Jinyue Dai; Lingge Suo; Haocheng Xian; Zhe Pan; Chun Zhang

Tags: exfoliation syndrome, mendelian randomization analysis, skin tanning, uv protection

Investigative Ophthalmology & Visual Science October 2023, Vol.64, 4. doi:https://doi.org/10.1167/iovs.64.13.4

Deep Optic Nerve Head Morphology in Tilted Disc Syndrome and Its Clinical Implication on Visual Damage Open Access

PDF

Eun Jung Lee; Jong Chul Han; Changwon Kee

Tags: optic disk, optic nerve hypoplasia, tilted optic disc, language morphology, morphology

Investigative Ophthalmology & Visual Science October 2023, Vol.64, 10. doi:https://doi.org/10.1167/iovs.64.13.10

The Structural Layers of the Porcine Iris Exhibit Inherently Different Biomechanical Properties Open Access

PDF

Royston K. Y. Tan; Satish K. Panda; Fabian A. Braeu; Arumugam R. Muralidharan; Monisha E. Nongpiur; Anita S. Y. Chan; Tin Aung; Raymond P. Najjar; Michaël J. A. Girard

Tags: body tissue, dilators, iris, suidae, permeability

Investigative Ophthalmology & Visual Science October 2023, Vol.64, 11. doi:https://doi.org/10.1167/iovs.64.13.11

Immunology and Microbiology

CRB1-Associated Retinal Dystrophy Patients Have Expanded Lewis Glycoantigen-Positive T Cells Open Access

PDF

Lude Moekotte; Jonas J. W. Kuiper; Sanne Hiddingh; Xuan-Thanh-An Nguyen; Camiel J. F. Boon; L. Ingeborgh van den Born; Joke H. de Boer; Maria M. van Genderen

Tags: retinal dystrophies, t-lymphocytes, flow cytometry

Investigative Ophthalmology & Visual Science October 2023, Vol.64, 6. doi:https://doi.org/10.1167/iovs.64.13.6

IL-8 Triggers Neutrophil Extracellular Trap Formation Through an Nicotinamide Adenine Dinucleotide Phosphate Oxidase- and Mitogen-Activated Protein Kinase Pathway-Dependent Mechanism in U... Open Access

PDF

Qinxin Shu; Ni Zhang; Yanyao Liu; Xing Wang; Jinquan Chen; Hao Xie; Fuying Pan; Long Zhao; Xuanheng Ding; Yan Wen; Lingda Wang; Wenxi Xie; Jing Lu; Guannan Su; Hui Peng; Peizeng Yang

Tags: interleukin-8, mitogen-activated protein kinases, nadp, uveitis, oxidase

Investigative Ophthalmology & Visual Science October 2023, Vol.64, 19. doi:https://doi.org/10.1167/iovs.64.13.19

Lens

Single-Cell RNA Sequencing Analysis of the Early Postnatal Mouse Lens Epithelium Open Access

PDF

Adrienne A. Giannone; Caterina Sellitto; Barbara Rosati; David McKinnon; Thomas W. White

Tags: genes, lens (device), lens epithelium, lens, crystalline, mice

Investigative Ophthalmology & Visual Science October 2023, Vol.64, 37. doi:https://doi.org/10.1167/iovs.64.13.37

Multidisciplinary Ophthalmic Imaging

A Fully Automatic Estimation of Tear Meniscus Height Using Artificial Intelligence Open Access

PDF

Shaopan Wang; Xin He; Jiezhou He; Shuang Li; Yuguang Chen; Changsheng Xu; Xiang Lin; Jie Kang; Wei Li; Zhiming Luo; Zuguo Liu

Tags: artificial intelligence, joint meniscus

Investigative Ophthalmology & Visual Science October 2023, Vol.64, 7. doi:https://doi.org/10.1167/iovs.64.13.7

Retina

Diabetes Reshapes the Circadian Transcriptome Profile in Murine Retina Open Access

PDF

Suna Ye; Zhijie Wang; Jacey Hongjie Ma; Shangli Ji; Yanfang Peng; Yinhua Huang; Jiansu Chen; Shibo Tang

Tags: diabetes mellitus, diabetes mellitus, type 2, mice, retina, rhythm

Investigative Ophthalmology & Visual Science October 2023, Vol.64, 3. doi:https://doi.org/10.1167/iovs.64.13.3

Pathophysiology of Secondary Macular Hole in Rhegmatogenous Retinal Detachment Open Access

PDF

Isabela Martins Melo; Aaditeya Jhaveri; Aditya Bansal; Wei Wei Lee; Paola L. Oquendo; Christine A. Curcio; Rajeev H. Muni

Tags: pathophysiology, rhegmatogenous retinal detachment, macular holes, photoreceptors, retinal detachment

Investigative Ophthalmology & Visual Science October 2023, Vol.64, 12. doi:https://doi.org/10.1167/iovs.64.13.12

Presumed Müller Cell Activation in Multiple Evanescent White Dot Syndrome Open Access

PDF

Maria Vittoria Cicinelli; Matteo Menean; Aurelio Apuzzo; Pierluigi Scandale; Alessandro Marchese; Ugo Introini; Maurizio Battaglia Parodi; Francesco Bandello; Elisabetta Miserocchi

Tags: multiple evanescent white dot syndrome

Investigative Ophthalmology & Visual Science October 2023, Vol.64, 20. doi:https://doi.org/10.1167/iovs.64.13.20

Inference of Capillary Nonperfusion Progression on Widefield OCT Angiography in Diabetic Retinopathy Open Access

PDF

Miyo Yoshida; Tomoaki Murakami; Kentaro Kawai; Keiichi Nishikawa; Kenji Ishihara; Yuki Mori; Akitaka Tsujikawa

Tags: angiogram, blood capillaries, diabetic retinopathy, inference, nasopharyngeal aspirate

Investigative Ophthalmology & Visual Science October 2023, Vol.64, 24. doi:https://doi.org/10.1167/iovs.64.13.24

Increased Oxygen Saturation in Retinal Venules During Isometric Exercise Is Accompanied With Increased Peripheral Blood Flow in Normal Persons Open Access

PDF

Jacob Drachmann; Signe Krejberg Jeppesen; Toke Bek

Tags: exercise, isometric, oxygen saturation measurement, peripheral circulation, vascular flow, retinal venule

Investigative Ophthalmology & Visual Science October 2023, Vol.64, 25. doi:https://doi.org/10.1167/iovs.64.13.25

Pupillary Light Reflex and Multimodal Imaging in Patients With Central Serous Chorioretinopathy Open Access

PDF

Xiaoyin Zhou; Hisashi Fukuyama; Takaaki Sugisawa; Yoichi Okita; Hiroyuki Kanda; Yuki Yamamoto; Takashi Araki; Fumi Gomi

Tags: central serous chorioretinopathy, pupil light reflex, multimodal imaging

Investigative Ophthalmology & Visual Science October 2023, Vol.64, 28. doi:https://doi.org/10.1167/iovs.64.13.28

Variability in Capillary Perfusion Is Increased in Regions of Retinal Ischemia Due to Branch Retinal Vein Occlusion Open Access

PDF

Martin Hein; Andrew Mehnert; K. Bailey Freund; Dao-Yi Yu; Chandrakumar Balaratnasingam

Tags: blood capillaries, ischemia, perfusion, retinal ischemia, venous retinal branch occlusion

Investigative Ophthalmology & Visual Science October 2023, Vol.64, 30. doi:https://doi.org/10.1167/iovs.64.13.30

Turnover of Microaneurysms After Intravitreal Injections of Faricimab for Diabetic Macular Edema Open Access

PDF

Yoshihiro Takamura; Yutaka Yamada; Masakazu Morioka; Makoto Gozawa; Takehiro Matsumura; Masaru Inatani

Tags: diabetic macular edema, faricimab, intravitreal injections, macrophage activation syndrome, meconium aspiration syndrome

Investigative Ophthalmology & Visual Science October 2023, Vol.64, 31. doi:https://doi.org/10.1167/iovs.64.13.31

Local Myeloid-Derived Suppressor Cells Impair Progression of Experimental Autoimmune Uveitis by Alleviating Oxidative Stress and Inflammation Open Access

PDF

Jae-Young Lee; Sueon Kim; Hyun-Jung Sohn; Chang-Hyun Kim; Tai-Gyu Kim; Hyun Soo Lee

Tags: myeloid-derived suppressor cells, uveitis, inflammation, oxidative stress

Investigative Ophthalmology & Visual Science October 2023, Vol.64, 39. doi:https://doi.org/10.1167/iovs.64.13.39

Retinal Dystrophy Associated With RLBP1 Retinitis Pigmentosa: A Five-Year Prospective Natural History Study Open Access

PDF

Marie Burstedt; James H. Whelan; Jane S. Green; Karen Holopigian; Claudio Spera; Erin Greco; Jean-Yves Deslandes; Michael Wald; Cynthia Grosskreutz; Xiao Ni; Guillaume Normand; Michael Maker; Arnaud Charil; Michael Rosol; Yunsheng He; Kalliopi Stasi

Tags: disease progression, eye, natural history, retinal dystrophies, retinitis pigmentosa

Investigative Ophthalmology & Visual Science October 2023, Vol.64, 42. doi:https://doi.org/10.1167/iovs.64.13.42

Silibinin Prevents TGFβ-Induced EMT of RPE in Proliferative Vitreoretinopathy by Inhibiting Stat3 and Smad3 Phosphorylation Open Access

PDF

Xinqi Ma; Yiyu Xie; Yajun Gong; Chuxuan Hu; Kairui Qiu; Yao Yang; Huangxuan Shen; Xiaolai Zhou; Chongde Long; Xiaofeng Lin

Tags: epithelial to mesenchymal transition, phosphorylation, silibinin, smad3 gene, stat3 protein

Investigative Ophthalmology & Visual Science October 2023, Vol.64, 47. doi:https://doi.org/10.1167/iovs.64.13.47

Retinal Cell Biology

METTL3-Mediated RNA m⁶A Modification Regulates the Angiogenic Behaviors of Retinal Endothelial Cells by Methylating MMP2 and TIE2 Open Access

PDF

Yong Lin; Guangying Luo; Qi Liu; Rusen Yang; Peter Sol Reinach; Dongsheng Yan

Tags: angiogenesis, endothelial cells, gelatinase a, hypoxia, mice

Investigative Ophthalmology & Visual Science October 2023, Vol.64, 18. doi:https://doi.org/10.1167/iovs.64.13.18

Gene Expression Within a Human Choroidal Neovascular Membrane Using Spatial Transcriptomics Open Access

PDF

Andrew P. Voigt; Nathaniel K. Mullin; Emma M. Navratil; Miles J. Flamme-Wiese; Li-Chun Lin; Todd E. Scheetz; Ian C. Han; Edwin M. Stone; Budd A. Tucker; Robert F. Mullins

Tags: choroidal neovascularization, gene expression, macular neovascularization, genes, sequence analysis, rna

Investigative Ophthalmology & Visual Science October 2023, Vol.64, 40. doi:https://doi.org/10.1167/iovs.64.13.40

Visual Neuroscience

CHIASM-Net: Artificial Intelligence-Based Direct Identification of Chiasmal Abnormalities in Albinism Open Access

PDF

Robert J. Puzniak; Gokulraj T. Prabhakaran; Rebecca J. McLean; Sebastian Stober; Sarim Ather; Frank A. Proudlock; Irene Gottlob; Robert A. Dineen; Michael B. Hoffmann

Tags: albinism, intelligence, optic chiasms, congenital abnormality

Investigative Ophthalmology & Visual Science October 2023, Vol.64, 14. doi:https://doi.org/10.1167/iovs.64.13.14

Integrative Transcriptome and Proteome Analyses Elucidate the Mechanism of Lens-Induced Myopia in Mice Open Access

PDF

Shunmei Ji; Lin Ye; Jiayue Yuan; Qianhong Feng; Jinhui Dai

Tags: lens (device), lens, crystalline, mice, myopia, proteome

Investigative Ophthalmology & Visual Science October 2023, Vol.64, 15. doi:https://doi.org/10.1167/iovs.64.13.15

Achromatopsia—Visual Cortex Stability and Plasticity in the Absence of Functional Cones Open Access

PDF

Barbara Molz; Anne Herbik; Heidi A. Baseler; Peter de Best; Noa Raz; Andre Gouws; Khazar Ahmadi; Rebecca Lowndes; Rebecca J. McLean; Irene Gottlob; Susanne Kohl; Lars Choritz; John Maguire; Martin Kanowski; Barbara Käsmann-Kellner; Ilse Wieland; Eyal Banin; Netta Levin; Antony B. Morland; Michael B. Hoffmann

Tags: achromatopsia, luminance, prolactin-releasing hormone, retinal cone, visual cortex

Investigative Ophthalmology & Visual Science October 2023, Vol.64, 23. doi:https://doi.org/10.1167/iovs.64.13.23

Letters to the Editor

Is Occasional Alcohol Drinking and Smoking Related to the Development of Age-Related Cataract? Open Access

PDF

Piotr Kanclerz; Idan Hecht; Raimo Tuuminen

Tags: alcohol drinking, cataract, senile, smoking

Investigative Ophthalmology & Visual Science October 2023, Vol.64, 8. doi:https://doi.org/10.1167/iovs.64.13.8

This feature is available to authenticated users only.

To View More...

You must be signed into an individual account to use this feature.