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Retinal Cell Biology October 2020

Modulation of Tmem135 Leads to Retinal Pigmented Epithelium Pathologies in Mice

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Michael Landowski; Samuel Grindel; Pawan K. Shahi; Abigail Johnson; Daniel Western; Adrienne Race; Franky Shi; Jonathan Benson; Marvin Gao; Evelyn Santoirre; Wei-Hua Lee; Sakae Ikeda; Bikash R. Pattnaik; Akihiro Ikeda

Invest. Ophthalmol. Vis. Sci.. 2020; 61(12):16. doi: https://doi.org/10.1167/iovs.61.12.16

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2020

Overexpression of TMEM135 Causes Progressive RPE Atrophy Dependent on Mouse Genetic Background

Samuel Grindel; Michael Landowski; Adrienne Race; Abigail Johnson; Daniel Western; Marvin Gao; Jonathan Benson; Evelyn Santoirre; Pawan Shahi; Wei-Hua Lee; Bikash R Pattnaik; Sakae Ikeda; Akihiro Ikeda

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):3536. doi:

ARVO Annual Meeting Abstract June 2020

Genomic analysis of cat lens and lens tumor

Akihiro Ikeda; Tetsuya Takimoto; Kazuya Oikawa; Sakae Ikeda; Gillian J McLellan; Nader Sheibani; Richard Dubielzig; Daniel Albert

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):3630. doi:

ARVO Annual Meeting Abstract June 2017

Altered fate of corneal epithelial cells in Dstn corn1 mice

Yuyun Zhu; Sharolyn Kawakami-Schulz; Wei-Hua Lee; Akihiro Ikeda; Winston W Y Kao; Sakae Ikeda

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):966. doi:

ARVO Annual Meeting Abstract June 2017

Metabolic alterations caused by dysregulation of mitochondrial dynamics in RPE cells

Wei-Hua Lee; Vijesh Bhute; Sarah Lewis; Hitoshi Higuchi; Sakae Ikeda; Sean P. Palecek; Akihiro Ikeda

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1604. doi:

ARVO Annual Meeting Abstract June 2017

Age-dependent retinal abnormalities and neurodegeneration in the small kinky tail mutant

Erica L Macke; Erika Henningsen; Erik Jessen; Hitoshi Higuchi; Samuel Miller; Sakae Ikeda; Akihiro Ikeda

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):4524. doi:

ARVO Annual Meeting Abstract September 2016

Early changes in optic nerve head (ONH) gene expression in a spontaneous glaucoma model

Kazuya Oikawa; James N Ver Hoeve; Leandro B C Teixeira; Julie Kiland; Elizabeth Hennes-Beean; Carol A Rasmussen; Xiao-yu Liu; Akihiro Ikeda; Matthew Ellinwood; Gillian J McLellan

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12) doi:

ARVO Annual Meeting Abstract September 2016

Phenome-wide association study provides biologic insights into the etiology of age-related macular degeneration

scott hebbring; John Mayer; Zhan Ye; Jixia Liu; Wei-hua Lee; Brian Hoch; Steven Schrodi; Jeffrey Joyce; Akihiro Ikeda; Murray Brilliant

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):2623. doi:

Genetics June 2015

A Mutation in Syne2 Causes Early Retinal Defects in Photoreceptors, Secondary Neurons, and Müller Glia

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Dennis M. Maddox; Gayle B. Collin; Akihiro Ikeda; C. Herbert Pratt; Sakae Ikeda; Britt A. Johnson; Ron E. Hurd; Lindsay S. Shopland; Jürgen K. Naggert; Bo Chang; Mark P. Krebs; Patsy M. Nishina
TAGS: electroretinography, homozygote, mice, mutation, neuroglia, neurons, photoreceptors, retina, retinal cone, rod photoreceptors
Invest. Ophthalmol. Vis. Sci.. 2015; 56(6):3776-3787. doi: https://doi.org/10.1167/iovs.14-16047

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2015

The role of Tmem135 in retinal aging and mitochondrial dynamics

Wei-Hua Lee; Hitoshi Higuchi; Erica Macke; Che Liu; Li-Fang Chu; John B Troy; Robert F Mullins; Joseph Takahashi; Lawrence Pinto; Akihiro Ikeda

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):5422. doi:

Genetics March 2012

An Allele of Microtubule-Associated Protein 1A ( Mtap1a ) Reduces Photoreceptor Degeneration in Tulp1 and Tub Mutant Mice

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Dennis M. Maddox; Sakae Ikeda; Akihiro Ikeda; Weidong Zhang; Mark P. Krebs; Patsy M. Nishina; Jürgen K. Naggert
TAGS: alleles, mice, photoreceptors, retinal degeneration, tissue degeneration, microtubule-associated proteins, genes, chromosomes, human, pair 2
Invest. Ophthalmol. Vis. Sci.. 2012; 53(3):1663-1669. doi: https://doi.org/10.1167/iovs.11-8871

ARVO Annual Meeting Abstract April 2011

The Age-dependent Retinal Synaptic Abnormality Is Affected By The Genetic Background

Hitoshi Higuchi; Sakae Ikeda; Akihiro Ikeda

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):1847. doi:

ARVO Annual Meeting Abstract April 2011

Phenotypic Variations in the Cornea of Destrin Mutants Caused by Allelic Differences and Genetic Modifiers

Sharolyn V. Kawakami-Schulz; Angela M. Verdoni; Akihiro Ikeda; Sakae Ikeda

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):6400. doi:

ARVO Annual Meeting Abstract April 2009

Microarray Analysis of Gene Expression Changes During Improvement of Schisis in Rs1tmgc1 Mice

A. Ikeda; B. A. Johnson; N. Aoyama; S. Ikeda

Invest. Ophthalmol. Vis. Sci.. 2009; 50(13):4140. doi:

ARVO Annual Meeting Abstract April 2009

Conditional Ablation of Srf in the Corneal Epithelium Rescues the Abnormalities in corn1 Mice

A. M. Verdoni; A. Ikeda; W. W. Kao; S. Ikeda

Invest. Ophthalmol. Vis. Sci.. 2009; 50(13):5199. doi:

ARVO Annual Meeting Abstract May 2008

Age-Related Formation of Ectopic Synapses in the Mouse Retina Is Suppressed by Calorie Restriction Through Mitochondrial Functions

A. Ikeda; N. Aoyama; S. Someya; G. C. Kujoth; T. A. Prolla

Invest. Ophthalmol. Vis. Sci.. 2008; 49(13):3997. doi:

ARVO Annual Meeting Abstract May 2008

Genetic Modification of the Schisis Phenotype in a Mouse Model of X-Linked Retinoschisis

B. A. Johnson; N. Aoyama; S. Ikeda; A. Ikeda

Invest. Ophthalmol. Vis. Sci.. 2008; 49(13):4035. doi:

ARVO Annual Meeting Abstract May 2008

The Effect of Actin Cytoskeletal Abnormalities on Gene Expression in corn1 Mice

A. M. Verdoni; N. Aoyama; A. Ikeda; S. Ikeda

Invest. Ophthalmol. Vis. Sci.. 2008; 49(13):4297. doi:

ARVO Annual Meeting Abstract May 2007

An Early Stop Codon in the Giant Scaffolding Protein Synaptic Nuclear Envelope 2 (Syne2) May Lead to Altered Synapse Morphology and Disorganization of the Outer Plexiform Layer (OPL) in Diminished Cone Electroretinogram (dice) Mice

D. M. Maddox; W. L. Hicks; A. Ikeda; S. Ikeda; R. S. Smith; N. L. Hawes; B. Chang; J. K. Naggert; P. M. Nishina

Invest. Ophthalmol. Vis. Sci.. 2007; 48(13):2987. doi:

ARVO Annual Meeting Abstract May 2007

Identification of a Major QTL, Which Modifies the Schisis and Layer Disorganization Phenotypes in Rs1htmgc1 Mice

B. A. Johnson; S. Ikeda; A. Ikeda

Invest. Ophthalmol. Vis. Sci.. 2007; 48(13):3000. doi:

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Modulation of Tmem135 Leads to Retinal Pigmented Epithelium Pathologies in Mice

Overexpression of TMEM135 Causes Progressive RPE Atrophy Dependent on Mouse Genetic Background

Genomic analysis of cat lens and lens tumor

Altered fate of corneal epithelial cells in Dstn corn1 mice

Metabolic alterations caused by dysregulation of mitochondrial dynamics in RPE cells

Age-dependent retinal abnormalities and neurodegeneration in the small kinky tail mutant

Early changes in optic nerve head (ONH) gene expression in a spontaneous glaucoma model

Phenome-wide association study provides biologic insights into the etiology of age-related macular degeneration

A Mutation in Syne2 Causes Early Retinal Defects in Photoreceptors, Secondary Neurons, and Müller Glia

The role of Tmem135 in retinal aging and mitochondrial dynamics

An Allele of Microtubule-Associated Protein 1A ( Mtap1a ) Reduces Photoreceptor Degeneration in Tulp1 and Tub Mutant Mice

The Age-dependent Retinal Synaptic Abnormality Is Affected By The Genetic Background

Phenotypic Variations in the Cornea of Destrin Mutants Caused by Allelic Differences and Genetic Modifiers

Microarray Analysis of Gene Expression Changes During Improvement of Schisis in Rs1tmgc1 Mice

Conditional Ablation of Srf in the Corneal Epithelium Rescues the Abnormalities in corn1 Mice

Age-Related Formation of Ectopic Synapses in the Mouse Retina Is Suppressed by Calorie Restriction Through Mitochondrial Functions

Genetic Modification of the Schisis Phenotype in a Mouse Model of X-Linked Retinoschisis

The Effect of Actin Cytoskeletal Abnormalities on Gene Expression in corn1 Mice

An Early Stop Codon in the Giant Scaffolding Protein Synaptic Nuclear Envelope 2 (Syne2) May Lead to Altered Synapse Morphology and Disorganization of the Outer Plexiform Layer (OPL) in Diminished Cone Electroretinogram (dice) Mice

Identification of a Major QTL, Which Modifies the Schisis and Layer Disorganization Phenotypes in Rs1htmgc1 Mice

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