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ARVO Annual Meeting Abstract June 2022

Activin A limits VEGF-induced permeability

Basma Baccouche; Lina Lietuvninkas; Yueru Li; Andrius Kazlauskas

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3602 – A0057. doi:

ARVO Annual Meeting Abstract June 2022

Hyperglycemia alters VEGF-induced permeability in retinal endothelial cells

Maximilian McCann; Yueru Li; Andrius Kazlauskas

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3594 – A0049. doi:

ARVO Annual Meeting Abstract June 2022

Hyperglycemia promotes mitophagy and thereby mitigates hyperglycemia-induced damage

Anara Serikbaeva; Ruth Zelkha; Destiny Ogbu; Yueru Li; Andrius Kazlauskas

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3621 – A0076. doi:

Retinal Cell Biology September 2021

The Role of the Wnt Pathway in VEGF/Anti-VEGF-Dependent Control of the Endothelial Cell Barrier

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Yueru Li; Basma Baccouche; Olamide Olayinka; Anara Serikbaeva; Andrius Kazlauskas
TAGS: endothelial cells, permeability, vascular endothelial growth factor a, anti-vascular endothelial growth factor therapy, endothelium, signal transduction
Invest. Ophthalmol. Vis. Sci.. 2021; 62(12):17. doi: https://doi.org/10.1167/iovs.62.12.17

Includes: Supplemental Content

Physiology and Pharmacology February 2021

VEGFR2 Trafficking by KIF13B Is a Novel Therapeutic Target for Wet Age-Related Macular Degeneration

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Stephen B. Waters; Christopher Zhou; Tara Nguyen; Ruth Zelkha; Hyun Lee; Andrius Kazlauskas; Mark I. Rosenblatt; Asrar B. Malik; Kaori H. Yamada
TAGS: choroidal neovascularization, exudative age-related macular degeneration, eyedrops, lasers, mice, peptides, vascular endothelial growth factor receptor-2, neovascularization, pathologic, eye, antibodies
Invest. Ophthalmol. Vis. Sci.. 2021; 62(2):5. doi: https://doi.org/10.1167/iovs.62.2.5

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2020

The Renin-Angiotensin-Aldosterone System (RAAS) is One of the Effectors used by VEGF/anti-VEGF to Control the Endothelial Cell Barrier.

Yueru Li; Komal Chaudhry; Andrius Kazlauskas

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):297. doi:

Cornea February 2017

PDGFRα Is a Key Regulator of T1 and T3's Differential Effect on SMA Expression in Human Corneal Fibroblasts

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Sriniwas Sriram; Jennifer A. Tran; Xiaoqing Guo; Audrey E. K. Hutcheon; Hetian Lei; Andrius Kazlauskas; James D. Zieske
TAGS: cell lines, cornea, fibroblasts, fluorescent antibody technique, transforming growth factor beta3, platelet-derived growth factor, polymerase chain reaction, growth factor, protein isoforms, transcription, genetic
Invest. Ophthalmol. Vis. Sci.. 2017; 58(2):1179-1186. doi: https://doi.org/10.1167/iovs.16-20016

ARVO Annual Meeting Abstract September 2016

Identifying the role of PDGFRα in the fibrotic pathway of TGF-β3

Sriniwas Sriram; Jennifer A Tran; Xiaoqing Q Guo; Hetian Lei; Andrius Kazlauskas; James D Zieske

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):2355. doi:

Biochemistry and Molecular Biology July 2016

Prevention of Proliferative Vitreoretinopathy by Suppression of Phosphatidylinositol 5-Phosphate 4-Kinases

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Gaoen Ma; Yajian Duan; Xionggao Huang; Cynthia X. Qian; Yewlin Chee; Shizuo Mukai; Jing Cui; Arif Samad; Joanne Aiko Matsubara; Andrius Kazlauskas; Patricia A. D'Amore; Shuyan Gu; Hetian Lei
TAGS: mice, oryctolagus cuniculus, phosphates, phosphatidylinositols, phosphotransferases, prevention, vitreoretinopathy, proliferative, vitreous body, western blotting, cell proliferation
Invest. Ophthalmol. Vis. Sci.. 2016; 57(8):3935-3943. doi: https://doi.org/10.1167/iovs.16-19405

ARVO Annual Meeting Abstract June 2015

PDGFRα is required for the anti-fibrotic action of TGFβ3

Sriniwas Sriram; Jennifer A Tran; Xiaoqing Q Guo; Andrius Kazlauskas; James D Zieske

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):719. doi:

ARVO Annual Meeting Abstract June 2015

AMD-Associated Silent Substitutions in HTRA1 Hijack the Unfolded Protein Response in RPE

Sarah Melissa Porras Jacobo; Andrius Kazlauskas

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):2596. doi:

ARVO Annual Meeting Abstract June 2015

A Role of Phosphatidylinoitol 5-Phosphate 4-Kinases in Proliferative Vitreoretinopathy

Hetian Lei; Andrius Kazlauskas

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):398. doi:

ARVO Annual Meeting Abstract June 2015

Development and Characterization of a new Mouse Model of Proliferative Diabetic Retinopathy

Ashley Michael Mackey; Jorge Aranda; Chiara Gerhardinger; Andrius Kazlauskas

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):4676. doi:

ARVO Annual Meeting Abstract June 2013

Ranibizumab is a potential prophylaxis for proliferative vitreoretinopathy, a non-angiogenic blinding disease

Steven Pennock; David Kim; Shizuo Mukai; Matthew Kuhnle; Dal Chun; Joanne Matsubara; Jing Cui; Patrick Ma; David Maberley; Andrius Kazlauskas

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):2849. doi:

ARVO Annual Meeting Abstract June 2013

AMD-associated silent polymorphisms in HtrA1 ameliorate IGF-1 antagonism

Sarah Melissa Jacobo; Margaret DeAngelis; Andrius Kazlauskas

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):4578. doi:

ARVO Annual Meeting Abstract June 2013

Epithelial cells promote fibroblast-mediated contraction of collagen gels by secreting bFGF

Maryada Sharma; Hetian Lei; Steven Pennock; Andrius Kazlauskas

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):6258. doi:

Translational Research February 2013

SU9518 Inhibits Proliferative Vitreoretinopathy in Fibroblast and Genetically Modified Müller Cell–Induced Rabbit Models

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Gisela Velez; Alexa R. Weingarden; Hetian Lei; Andrius Kazlauskas; Guangping Gao
TAGS: fibroblasts, oryctolagus cuniculus, vitreoretinopathy, proliferative, eye
Invest. Ophthalmol. Vis. Sci.. 2013; 54(2):1392-1397. doi: https://doi.org/10.1167/iovs.12-10320

Retina July 2012

A Phage Display-Based Approach to Investigate Abnormal Neovessels of the Retina

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Magdalena Staniszewska; Xiaolin Gu; Carmelo Romano; Andrius Kazlauskas
TAGS: bacteriophages, retina, peptides
Invest. Ophthalmol. Vis. Sci.. 2012; 53(8):4371-4379. doi: https://doi.org/10.1167/iovs.12-9690

Includes: Multimedia, Supplemental Content

ARVO Annual Meeting Abstract March 2012

Viral Vectors For Gene Transfer To Corneal Endothelial Cells

Thomas A. Fuchsluger; Ula V. Jurkunas; Andrius Kazlauskas; Reza Dana

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):5998. doi:

ARVO Annual Meeting Abstract March 2012

A Novel Function of p53: A Gatekeeper of Retinal Detachment

Hetian Lei; Marc-Andr Rheaume; Jing Z. Cui; Shizuo Mukai; David Maberley; Arif Samad; Joanne A. Matsubara; Andrius Kazlauskas

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):894. doi:

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Activin A limits VEGF-induced permeability

Hyperglycemia alters VEGF-induced permeability in retinal endothelial cells

Hyperglycemia promotes mitophagy and thereby mitigates hyperglycemia-induced damage

The Role of the Wnt Pathway in VEGF/Anti-VEGF-Dependent Control of the Endothelial Cell Barrier

VEGFR2 Trafficking by KIF13B Is a Novel Therapeutic Target for Wet Age-Related Macular Degeneration

The Renin-Angiotensin-Aldosterone System (RAAS) is One of the Effectors used by VEGF/anti-VEGF to Control the Endothelial Cell Barrier.

PDGFRα Is a Key Regulator of T1 and T3's Differential Effect on SMA Expression in Human Corneal Fibroblasts

Identifying the role of PDGFRα in the fibrotic pathway of TGF-β3

Prevention of Proliferative Vitreoretinopathy by Suppression of Phosphatidylinositol 5-Phosphate 4-Kinases

PDGFRα is required for the anti-fibrotic action of TGFβ3

AMD-Associated Silent Substitutions in HTRA1 Hijack the Unfolded Protein Response in RPE

A Role of Phosphatidylinoitol 5-Phosphate 4-Kinases in Proliferative Vitreoretinopathy

Development and Characterization of a new Mouse Model of Proliferative Diabetic Retinopathy

Ranibizumab is a potential prophylaxis for proliferative vitreoretinopathy, a non-angiogenic blinding disease

AMD-associated silent polymorphisms in HtrA1 ameliorate IGF-1 antagonism

Epithelial cells promote fibroblast-mediated contraction of collagen gels by secreting bFGF

SU9518 Inhibits Proliferative Vitreoretinopathy in Fibroblast and Genetically Modified Müller Cell–Induced Rabbit Models

A Phage Display-Based Approach to Investigate Abnormal Neovessels of the Retina

Viral Vectors For Gene Transfer To Corneal Endothelial Cells

A Novel Function of p53: A Gatekeeper of Retinal Detachment

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