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Physiology and Pharmacology February 2021

VEGFR2 Trafficking by KIF13B Is a Novel Therapeutic Target for Wet Age-Related Macular Degeneration

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Stephen B. Waters; Christopher Zhou; Tara Nguyen; Ruth Zelkha; Hyun Lee; Andrius Kazlauskas; Mark I. Rosenblatt; Asrar B. Malik; Kaori H. Yamada
TAGS: choroidal neovascularization, exudative age-related macular degeneration, eyedrops, lasers, mice, peptides, vascular endothelial growth factor receptor-2, neovascularization, pathologic, eye, antibodies
Invest. Ophthalmol. Vis. Sci.. 2021; 62(2):5. doi: https://doi.org/10.1167/iovs.62.2.5

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2020

The Renin-Angiotensin-Aldosterone System (RAAS) is One of the Effectors used by VEGF/anti-VEGF to Control the Endothelial Cell Barrier.

Yueru Li; Komal Chaudhry; Andrius Kazlauskas

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):297. doi:

Cornea February 2017

PDGFRα Is a Key Regulator of T1 and T3's Differential Effect on SMA Expression in Human Corneal Fibroblasts

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Sriniwas Sriram; Jennifer A. Tran; Xiaoqing Guo; Audrey E. K. Hutcheon; Hetian Lei; Andrius Kazlauskas; James D. Zieske
TAGS: cell lines, cornea, fibroblasts, fluorescent antibody technique, transforming growth factor beta3, platelet-derived growth factor, polymerase chain reaction, growth factor, protein isoforms, transcription, genetic
Invest. Ophthalmol. Vis. Sci.. 2017; 58(2):1179-1186. doi: https://doi.org/10.1167/iovs.16-20016

ARVO Annual Meeting Abstract September 2016

Identifying the role of PDGFRα in the fibrotic pathway of TGF-β3

Sriniwas Sriram; Jennifer A Tran; Xiaoqing Q Guo; Hetian Lei; Andrius Kazlauskas; James D Zieske

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):2355. doi:

Biochemistry and Molecular Biology July 2016

Prevention of Proliferative Vitreoretinopathy by Suppression of Phosphatidylinositol 5-Phosphate 4-Kinases

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Gaoen Ma; Yajian Duan; Xionggao Huang; Cynthia X. Qian; Yewlin Chee; Shizuo Mukai; Jing Cui; Arif Samad; Joanne Aiko Matsubara; Andrius Kazlauskas; Patricia A. D'Amore; Shuyan Gu; Hetian Lei
TAGS: mice, oryctolagus cuniculus, phosphates, phosphatidylinositols, phosphotransferases, prevention, vitreoretinopathy, proliferative, vitreous body, western blotting, cell proliferation
Invest. Ophthalmol. Vis. Sci.. 2016; 57(8):3935-3943. doi: https://doi.org/10.1167/iovs.16-19405

ARVO Annual Meeting Abstract June 2015

PDGFRα is required for the anti-fibrotic action of TGFβ3

Sriniwas Sriram; Jennifer A Tran; Xiaoqing Q Guo; Andrius Kazlauskas; James D Zieske

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):719. doi:

ARVO Annual Meeting Abstract June 2015

AMD-Associated Silent Substitutions in HTRA1 Hijack the Unfolded Protein Response in RPE

Sarah Melissa Porras Jacobo; Andrius Kazlauskas

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):2596. doi:

ARVO Annual Meeting Abstract June 2015

A Role of Phosphatidylinoitol 5-Phosphate 4-Kinases in Proliferative Vitreoretinopathy

Hetian Lei; Andrius Kazlauskas

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):398. doi:

ARVO Annual Meeting Abstract June 2015

Development and Characterization of a new Mouse Model of Proliferative Diabetic Retinopathy

Ashley Michael Mackey; Jorge Aranda; Chiara Gerhardinger; Andrius Kazlauskas

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):4676. doi:

ARVO Annual Meeting Abstract June 2013

Ranibizumab is a potential prophylaxis for proliferative vitreoretinopathy, a non-angiogenic blinding disease

Steven Pennock; David Kim; Shizuo Mukai; Matthew Kuhnle; Dal Chun; Joanne Matsubara; Jing Cui; Patrick Ma; David Maberley; Andrius Kazlauskas

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):2849. doi:

ARVO Annual Meeting Abstract June 2013

AMD-associated silent polymorphisms in HtrA1 ameliorate IGF-1 antagonism

Sarah Melissa Jacobo; Margaret DeAngelis; Andrius Kazlauskas

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):4578. doi:

ARVO Annual Meeting Abstract June 2013

Epithelial cells promote fibroblast-mediated contraction of collagen gels by secreting bFGF

Maryada Sharma; Hetian Lei; Steven Pennock; Andrius Kazlauskas

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):6258. doi:

Translational Research February 2013

SU9518 Inhibits Proliferative Vitreoretinopathy in Fibroblast and Genetically Modified Müller Cell–Induced Rabbit Models

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Gisela Velez; Alexa R. Weingarden; Hetian Lei; Andrius Kazlauskas; Guangping Gao
TAGS: fibroblasts, oryctolagus cuniculus, vitreoretinopathy, proliferative, eye
Invest. Ophthalmol. Vis. Sci.. 2013; 54(2):1392-1397. doi: https://doi.org/10.1167/iovs.12-10320

Retina July 2012

A Phage Display-Based Approach to Investigate Abnormal Neovessels of the Retina

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Magdalena Staniszewska; Xiaolin Gu; Carmelo Romano; Andrius Kazlauskas
TAGS: bacteriophages, retina, peptides
Invest. Ophthalmol. Vis. Sci.. 2012; 53(8):4371-4379. doi: https://doi.org/10.1167/iovs.12-9690

Includes: Multimedia, Supplemental Content

ARVO Annual Meeting Abstract March 2012

A Novel Function of p53: A Gatekeeper of Retinal Detachment

Hetian Lei; Marc-Andr Rheaume; Jing Z. Cui; Shizuo Mukai; David Maberley; Arif Samad; Joanne A. Matsubara; Andrius Kazlauskas

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):894. doi:

ARVO Annual Meeting Abstract March 2012

Viral Vectors For Gene Transfer To Corneal Endothelial Cells

Thomas A. Fuchsluger; Ula V. Jurkunas; Andrius Kazlauskas; Reza Dana

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):5998. doi:

Biochemistry and Molecular Biology August 2011

Expression of PDGFRα Is a Determinant of the PVR Potential of ARPE19 Cells

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Hetian Lei; Marc-André Rhéaume; Gisela Velez; Shizuo Mukai; Andrius Kazlauskas
TAGS: oryctolagus cuniculus, retinal pigment cell, signal transduction, vitreous body, fibroblasts, western blotting, apoptosis, collagen, tissue membrane
Invest. Ophthalmol. Vis. Sci.. 2011; 52(9):5016-5021. doi: https://doi.org/10.1167/iovs.11-7442

Includes: Supplemental Content

ARVO Annual Meeting Abstract April 2011

Expression Of PDGFRα In Retinal Pigment Epithelial Cells Promotes Experimental Proliferative Vitreoretinopathy

Hetian Lei; Marc-Andre Rheaume; Gisela Velez; Shizuo mukai; Andrius Kazlauskas

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):6590. doi:

ARVO Annual Meeting Abstract April 2011

A Novel Strategy To Develop Therapeutic Approaches To Prevent Proliferative Vitreoretinopathy

Steven Pennock; Marc-Andre Rheaume; Shizuo Mukai; Joanne A. Matsubara; Jing Cui; David Maberley; Patrick Ma; Arif Samad; R.J. van Geest; Andrius Kazlauskas

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):4924. doi:

ARVO Annual Meeting Abstract April 2011

SU9518 Inhibits Proliferative Vitreoretinopathy (PVR) in a Muller Cell Rabbit Model of PVR

Gisela Velez; Hetian Lei; Andrius Kazlauskas; Shalesh Kaushal; Michael Young

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):2065. doi:

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VEGFR2 Trafficking by KIF13B Is a Novel Therapeutic Target for Wet Age-Related Macular Degeneration

The Renin-Angiotensin-Aldosterone System (RAAS) is One of the Effectors used by VEGF/anti-VEGF to Control the Endothelial Cell Barrier.

PDGFRα Is a Key Regulator of T1 and T3's Differential Effect on SMA Expression in Human Corneal Fibroblasts

Identifying the role of PDGFRα in the fibrotic pathway of TGF-β3

Prevention of Proliferative Vitreoretinopathy by Suppression of Phosphatidylinositol 5-Phosphate 4-Kinases

PDGFRα is required for the anti-fibrotic action of TGFβ3

AMD-Associated Silent Substitutions in HTRA1 Hijack the Unfolded Protein Response in RPE

A Role of Phosphatidylinoitol 5-Phosphate 4-Kinases in Proliferative Vitreoretinopathy

Development and Characterization of a new Mouse Model of Proliferative Diabetic Retinopathy

Ranibizumab is a potential prophylaxis for proliferative vitreoretinopathy, a non-angiogenic blinding disease

AMD-associated silent polymorphisms in HtrA1 ameliorate IGF-1 antagonism

Epithelial cells promote fibroblast-mediated contraction of collagen gels by secreting bFGF

SU9518 Inhibits Proliferative Vitreoretinopathy in Fibroblast and Genetically Modified Müller Cell–Induced Rabbit Models

A Phage Display-Based Approach to Investigate Abnormal Neovessels of the Retina

A Novel Function of p53: A Gatekeeper of Retinal Detachment

Viral Vectors For Gene Transfer To Corneal Endothelial Cells

Expression of PDGFRα Is a Determinant of the PVR Potential of ARPE19 Cells

Expression Of PDGFRα In Retinal Pigment Epithelial Cells Promotes Experimental Proliferative Vitreoretinopathy

A Novel Strategy To Develop Therapeutic Approaches To Prevent Proliferative Vitreoretinopathy

SU9518 Inhibits Proliferative Vitreoretinopathy (PVR) in a Muller Cell Rabbit Model of PVR

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