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ARVO Annual Meeting Abstract June 2022

Morphometric analysis of the human retinal pigment epithelium indicates regional susceptibilities to disease

Sharanya Suresh; Davide Ortolan; Ruchi Sharma; Andrei Volkov; Arvydas Maminishkis; Nathan Hotaling; Kapil Bharti

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):4623 – F0415. doi:

ARVO Annual Meeting Abstract June 2022

Single cell resolution map of retinal pigment epithelium helps discover subpopulations with differential disease sensitivity

Davide Ortolan; Ruchi Sharma; Andrei Volkov; Arvydas Maminishkis; Nathan Hotaling; Laryssa Huryn; Stefano Di Marco; Silvia Bisti; Kapil Bharti

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):4616 – F0408. doi:

ARVO Annual Meeting Abstract June 2022

Automatic retinal layer segmentation in OCT images of a laser induced porcine model for retinal injury

Rohan Gupta; Samuel Heaps; Bruno Alvisio; Francesca BARONE; Arvydas Maminishkis; Juan Amaral; Irina Bunea; Kristi Creel; Mitra Farnoodian; Kapil Bharti

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2081 – F0070. doi:

ARVO Annual Meeting Abstract June 2022

Retinal Pigment Epithelium Modulates Endothelial Cell, Fibroblast, and Pericyte Gene Expression Patterns in 3D Bioprinted Tissues

Eric Nguyen; Min Jae Song; Russell Quinn; Tea Soon Park; Yu-Chi Chen; Claire Malley; Carlos Tristan; Devika Bose; Ruchi Sharma; Roba Dejene; Amir Ali; Rishabh Hirday; Arvydas Maminishkis; Ilyas Singec; Marc Ferrer; Kapil Bharti

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3027 – F0398. doi:

ARVO Annual Meeting Abstract June 2021

Using Adaptive Optics to Evaluate Photoreceptor Regularity in a Porcine Laser Model Mimicking Age-Related Macular Degeneration

Rishabh Gupta; Francesca BARONE; Dara Baker; Devika Bose; Haig Pakhchanian; Irina Bunea; Arvydas Maminishkis; Davide Ortolan; Joe Phillips; Ruchi Sharma; Juan Amaral; David Gamm; Kapil Bharti

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):11. doi:

ARVO Annual Meeting Abstract June 2021

Optical Coherence Tomography Angiography (OCTA) caracterization of the choriocapillaris in a laser pig model of retinal degeneration

Francesca BARONE; Rishabh Gupta; Ruchi Sharma; Juan Amaral; Irina Bunea; Arvydas Maminishkis; Joe Phillips; David Gamm; Kapil Bharti

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):378. doi:

ARVO Annual Meeting Abstract June 2021

Chronic Oxidative Stress in Primary Retinal Pigmented Epithelium Monolayers Increases Basolateral Exosome Release and Changes Both Exosome and Extracellular Matrix Proteomes

Belinda Hernandez; Mikael Klingeborn; Nikolai Skiba; Daniel Grigsby; Una Kelly; Martha Caday; Arvydas Maminishkis; TeddiJo Watkins; Sheldon S Miller; W. Daniel Stamer; Catherine Bowes Rickman

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):256. doi:

ARVO Annual Meeting Abstract June 2021

Modeling the outer blood-retina barrier using microfluidic chips and iPSC-derived RPE and endothelial cells

Tea Soon Park; Eric Nguyen; Haig Pakhchanian; Davide Ortolan; Nikhil Vettikatu; Roba Dejene; Devika Bose; Genqing Liang; Ruchi Sharma; Arvydas Maminishkis; Kapil Bharti

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2192. doi:

ARVO Annual Meeting Abstract June 2021

The human retinal pigment epithelium has five morphometrically distinct subpopulations which present differential disease vulnerability

Davide Ortolan; Ruchi Sharma; Andrei Volkov; Arvydas Maminishkis; Jorge Ferrari Escoto; Nathan Hotaling; Stefano Di Marco; Silvia Bisti; Kapil Bharti

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2717. doi:

ARVO Annual Meeting Abstract June 2020

Hypoxia-induced Alterations of miR-204 Regulates Autophagy Activity in Human Retinal Pigment Epithelium (hRPE)

Congxiao Zhang; Kiyoharu J Miyagishima; Ruchi Sharma; Malika Nimmagadda; Genqing Liang; Arvydas Maminishkis; Kapil Bharti; Sheldon S Miller

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):3110. doi:

ARVO Annual Meeting Abstract June 2020

At-line functional characterization of iPSC-derived retinal pigment epithelium

Colby Foster Lewallen; Qin Wan; Arvydas Maminishkis; Kapil Bharti; Craig R. Forest

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):4127. doi:

ARVO Annual Meeting Abstract July 2019

Elevation of miR-155 induces a non-canonical inflammasome activation pathway in human retinal pigment epithelium (hRPE)

Congxiao Zhang; Arvydas Maminishkis; Kiyoharu miyagishima; Genqing Liang; Fnu Ruchi; Sheldon S Miller

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):766. doi:

ARVO Annual Meeting Abstract July 2019

Regional transcriptome map of the adult rhesus macaque retina and RPE-choroid

Ameera Mungale; Temesgen D Fufa; David McGaughey; Congxiao Zhang; Arvydas Maminishkis; Sheldon S Miller; Brian Patrick Brooks; Robert Hufnagel

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):998. doi:

ARVO Annual Meeting Abstract July 2019

Fibulin-3 mutation induces loss of polarity in RPE cells and alters the protein and micro RNA content of exosomes

Mi Zhou; Sarah Weber; Yuanjun Zhao; Yuka Imamura; Arvydas Maminishkis; Sheldon S Miller; Jeffrey M. Sundstrom

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1917. doi:

ARVO Annual Meeting Abstract July 2019

Towards automated intracellular electrophysiology of retinal pigment epithelium

Colby Foster Lewallen; Qin Wan; Arvydas Maminishkis; William Stoy; Ilya Kolb; Nathan Hotaling; Kapil Bharti; Craig R. Forest

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1938. doi:

ARVO Annual Meeting Abstract July 2019

Tissue Engineered Macular Edema-On-A-Chip

Haig Pakhchanian; Eric Nguyen; Nathan Hotaling; Davide Ortolan; Roba Dejene; Arvydas Maminishkis; Kapil Bharti

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2863. doi:

ARVO Annual Meeting Abstract July 2019

Transplantation of Bio-Printed Choroid-RPE Tissue into The Subretinal Space of Rats

Céline Koster; Francesca Barone; Arvydas Maminishkis; Min Jae Song; Russell Quinn; Colby F Lewallen; Jan van Meurs; Kapil Bharti; Arthur A Bergen

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3275. doi:

ARVO Annual Meeting Abstract July 2019

Altered electrical responses in iPSC-RPE derived from distinct genetic eye diseases

Qin Wan; Mitra Farnoodian; Nathan Hotaling; Aman George; Kiyoharu miyagishima; Roba Dejene; Tyler Pfister; Arvydas Maminishkis; Brian Patrick Brooks; Sheldon S Miller; Kapil Bharti

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):6396. doi:

ARVO Annual Meeting Abstract July 2018

Human Retinal Pigment Epithelium Transcriptional Response to Stress Induced by Advanced Glycation End Products and Lipid Peroxidation

Wasu Supharattanasitthi; Joe M. Butler; Arvydas Maminishkis; Yit C. Yang; Luminita I Paraoan

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):2349. doi:

ARVO Annual Meeting Abstract July 2018

TLR2 bridges oxidative damage and complement-associated pathology and is a therapeutic target for age-related macular degeneration.

Sarah Doyle; Kelly Mulfaul; Nilisha Fernando; Kathleen Chirco; Emma Connolly; Tony Ryan; Ema Ozaki; Kiva Brennan; Arvydas Maminishkis; Robert Salomon; Riccardo Natoli; Robert F Mullins; Matthew Campbell

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3475. doi:

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Morphometric analysis of the human retinal pigment epithelium indicates regional susceptibilities to disease

Single cell resolution map of retinal pigment epithelium helps discover subpopulations with differential disease sensitivity

Automatic retinal layer segmentation in OCT images of a laser induced porcine model for retinal injury

Retinal Pigment Epithelium Modulates Endothelial Cell, Fibroblast, and Pericyte Gene Expression Patterns in 3D Bioprinted Tissues

Using Adaptive Optics to Evaluate Photoreceptor Regularity in a Porcine Laser Model Mimicking Age-Related Macular Degeneration

Optical Coherence Tomography Angiography (OCTA) caracterization of the choriocapillaris in a laser pig model of retinal degeneration

Chronic Oxidative Stress in Primary Retinal Pigmented Epithelium Monolayers Increases Basolateral Exosome Release and Changes Both Exosome and Extracellular Matrix Proteomes

Modeling the outer blood-retina barrier using microfluidic chips and iPSC-derived RPE and endothelial cells

The human retinal pigment epithelium has five morphometrically distinct subpopulations which present differential disease vulnerability

Hypoxia-induced Alterations of miR-204 Regulates Autophagy Activity in Human Retinal Pigment Epithelium (hRPE)

At-line functional characterization of iPSC-derived retinal pigment epithelium

Elevation of miR-155 induces a non-canonical inflammasome activation pathway in human retinal pigment epithelium (hRPE)

Regional transcriptome map of the adult rhesus macaque retina and RPE-choroid

Fibulin-3 mutation induces loss of polarity in RPE cells and alters the protein and micro RNA content of exosomes

Towards automated intracellular electrophysiology of retinal pigment epithelium

Tissue Engineered Macular Edema-On-A-Chip

Transplantation of Bio-Printed Choroid-RPE Tissue into The Subretinal Space of Rats

Altered electrical responses in iPSC-RPE derived from distinct genetic eye diseases

Human Retinal Pigment Epithelium Transcriptional Response to Stress Induced by Advanced Glycation End Products and Lipid Peroxidation

TLR2 bridges oxidative damage and complement-associated pathology and is a therapeutic target for age-related macular degeneration.

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