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ARVO Annual Meeting Abstract June 2022

Bone morphogenetic protein 2 contributes to diabetes-induced extracellular matrix deposition and apoptosis in retinal microvasculature

Khaled Elmasry; Ahmed S Ibrahim; Mohamed Moustafa; Yunjoo Shin; Kathereen Albishara; Mohamed Al-Sayed Al-Shabrawey

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3597 – A0052.

ARVO Annual Meeting Abstract June 2021

Tranilast protects against endoplasmic reticulum stress-induced cell death in retinal pigment epithelial cells: Implications for age-related retinal diseases

Thangal Yumnamcha; Michael Guerra; Ebrahim Abdul-Shukkur; Elizabeth A Berger; Lalit S Pukhrambam; Ahmed S Ibrahim

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):326.

ARVO Annual Meeting Abstract June 2021

Application of Electric Cell-Substrate Impedance Sensing (ECIS) to investigate the effect of mitochondrial bioenergetics on retinal pigment epithelial barrier functionality

Michael Hayden GUERRA; Thangal Yumnamcha; Lalit P Singh; Ahmed S Ibrahim

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2963.

ARVO Annual Meeting Abstract June 2020

Metabolic Bioenergetic Signature of Inner and Outer Blood Retinal Barrier Cells

Ahmed S Ibrahim; Shaimaa Eltanani; Thangal Yumnamcha; Lalit P Singh

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):4155.

ARVO Annual Meeting Abstract July 2019

A Bioactive Small Molecule Derivative of Fluoro-catechol Ester of 3-Hydroxy-Benzoic Acid Inhibits High Glucose/Hypoxia-Induced Endothelial Switch to Angiogenic Phenotype in Diabetes Induced Retinal Microvasculopathy

Ahmed S Ibrahim; Shaimaa Eltanani; Heba Saleh; Ibrahim Eldeeb; Farid Badria; Mohamed Al-Sayed Al-Shabrawey

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5709.

Retina November 2018

A Controlled Impact of Optic Nerve as a New Model of Traumatic Optic Neuropathy in Mouse

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Ahmed S. Ibrahim; Khaled Elmasry; Ming Wan; Samer Abdulmoneim; Amber Still; Farid Khan; Abraham Khalil; Alan Saul; Md Nasrul Hoda; Mohamed Al-Shabrawey
TAGS: eye, mice, optic nerve, optic nerve injuries, wounds and injuries, electroretinography, velocity
Invest. Ophthalmol. Vis. Sci.. 2018; 59(13):5548-5557. https://doi.org/10.1167/iovs.18-24773

Includes: Multimedia, Supplemental Content

ARVO Annual Meeting Abstract July 2018

12/15-lipoxygenase contributes to retinal inflammation in diabetic retinopathy via activation of ER stress/NADPH oxidase signaling pathway

Khaled Elmasry; Ahmed S Ibrahim; Heba Saleh; Nehal Elsherbiny; Sally Elshafey; Khaled Hussein; Mohamed Al-Sayed Al-Shabrawey

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1594.

ARVO Annual Meeting Abstract June 2017

Endothelial but not Leukocytic 12/15-Lipoxygenase Contributes to Retinal Leukostasis in Diabetic Retinopathy

Ahmed S Ibrahim; Mohamed El-Shafey; Heba M Saleh; Khaled Elmasry; Nader Sheibani; Amany Tawfik; Mohamed Al-Sayed Al-Shabrawey

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):5215.

Retinal Cell Biology February 2017

Adenosine Deaminase-2–Induced Hyperpermeability in Human Retinal Vascular Endothelial Cells Is Suppressed by MicroRNA-146b-3p

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Yara A. Samra; Heba M. Saleh; Khaled A. Hussein; Nehal M. Elsherbiny; Ahmed S. Ibrahim; Khaled Elmasry; Sadanand Fulzele; Mamdouh M. El-Shishtawy; Laila A. Eissa; Mohamed Al-Shabrawey; Gregory I. Liou
TAGS: adenosine, albumins, cecr1 gene, diabetic retinopathy, endothelial cells, macrophages, micrornas, cytokine, interleukin-6, tumor necrosis factors
Invest. Ophthalmol. Vis. Sci.. 2017; 58(2):933-943. https://doi.org/10.1167/iovs.16-19782

ARVO Annual Meeting Abstract September 2016

Hyperhomocysteinemia Disrupts Retinal Pigment Epithelial Structure and Function with Features of Age-Related Macular Degeneration

Amany M Tawfik; Ahmed S Ibrahim; Nehal Elsherbini; Sylvia B Smith; Mohamed Al-Sayed Al-Shabrawey

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12)

ARVO Annual Meeting Abstract September 2016

Differential Activity of Systemic and Retinal 12/15-Lipoxygenases in a Mouse Model of Diabetes

Ahmed S Ibrahim; Heba M Saleh; Khaled Hussein; Babak Baban; Nader Sheibani; Mohamed Al-Sayed Al-Shabrawey

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):1756.

ARVO Annual Meeting Abstract September 2016

NOX4 Stabilizes Barrier Function of Human Retinal Endothelial Cells and Retinal Pigment Epithelial Cells

Heba Mohamed Saleh; Khaled Hussein; Ahmed S Ibrahim; Khaled Elmasry; Nehal M El-Sherbiny; David Fulton; Mohamed Al-Sayed Al-Shabrawey

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):3216.

ARVO Annual Meeting Abstract September 2016

Elevated homocysteine in the vitreous of diabetic patients and blood of type 1 and 2 diabetic animal models; Potential role of homocysteine in blood retinal barrier dysfunction

Isha Sharma; Ahmed S Ibrahim; Heba Mohamed Saleh; Shaikh Rizwan; Gregory Ing Liou; Mohamed Al-Sayed Al-Shabrawey; Amany M Tawfik

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):3218.

ARVO Annual Meeting Abstract September 2016

Exosomes Released From Human Retinal Endothelial Cells Upon 15-HETE Treatment or ER Stress Induction: Potential Role of Nanoparticles in Diabetic Retinopathy

Khaled Elmasry; Khaled Hussein; Heba Mohamed Saleh; Ahmed S Ibrahim; Nehal M El-Sherbiny; Inas Helwa; Yutao Liu; Mohamed Al-Sayed Al-Shabrawey

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):3230.

ARVO Annual Meeting Abstract September 2016

BMP2 and 4 Contribute to Retinal Endothelial Cell Barrier Dysfunction in Diabetic Retinopathy: Role of p38 MAPK Pathway

Khaled Hussein; Fang Wang; Ahmed S Ibrahim; Heba Mohamed Saleh; Khaled Elmasry; Nehal M El-Sherbiny; Paul Yu; Mohamed Al-Sayed Al-Shabrawey

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):5448.

ARVO Annual Meeting Abstract June 2015

12/15-Lipoxygenase Gene Deletion Attenuates Blood-Retinal Barrier Dysfunction During Diabetic Retinopathy: Contribution of ER Stress

Ahmed S Ibrahim; Khaled Hussein; Amany M Tawfik; Nasser Rizk; Sylvia B Smith; Mohamed Al-Sayed Al-Shabrawey

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):5852.

ARVO Annual Meeting Abstract June 2015

Supplementing Dietary DHA Attenuates Traumatic Optic Neuropathy by Manipulating 12/15-Lipoxygenase Activity

Farid M Khan; Ahmed S Ibrahim; amber still; Alan Saul; Nasrul Hoda; Mohamed Al-Sayed Al-Shabrawey; Al-Shabrawey Laboratory at Georgia Regents University

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):6028.

ARVO Annual Meeting Abstract April 2014

Pro-inflammatory effect of 12/15-lipoxygenase derived lipid metabolites in retina: Role of Pigment epithelium-derived factor (PEDF) suppression

Ahmed S Ibrahim; Amany M Tawfik; Sally Elshafey; Elia J Duh; Sylvia B Smith; Mohamed Al-Shabrawey; Lipid dyslipidemia and retinopathy

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):2258.

ARVO Annual Meeting Abstract April 2014

12/15-Lipoxygenase-Derived Eicosanoids Induce Vascular Inflammation and Angiogenic Effects in Human Retinal Endothelial Cells: Role of NADPH oxidase and ER Stress

Sally El-shafey; Mohamed El-Sherbiny; Amira Othman; Ahmed S Ibrahim; Mohammed A Abdelsaid; Nasser Rizk; Mohamed Al-Shabrawey; Diabetic retinopathy

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):5398.

ARVO Annual Meeting Abstract April 2011

Cannabidiol Dampens Streptozotocin-Induced Retinal Inflammation by Targeting of Microglial Activation

Gregory I. Liou; Mamdouh M. El-Shishtawy; Ahmed S. Ibrahim

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):1002.

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Bone morphogenetic protein 2 contributes to diabetes-induced extracellular matrix deposition and apoptosis in retinal microvasculature

Tranilast protects against endoplasmic reticulum stress-induced cell death in retinal pigment epithelial cells: Implications for age-related retinal diseases

Application of Electric Cell-Substrate Impedance Sensing (ECIS) to investigate the effect of mitochondrial bioenergetics on retinal pigment epithelial barrier functionality

Metabolic Bioenergetic Signature of Inner and Outer Blood Retinal Barrier Cells

A Bioactive Small Molecule Derivative of Fluoro-catechol Ester of 3-Hydroxy-Benzoic Acid Inhibits High Glucose/Hypoxia-Induced Endothelial Switch to Angiogenic Phenotype in Diabetes Induced Retinal Microvasculopathy

A Controlled Impact of Optic Nerve as a New Model of Traumatic Optic Neuropathy in Mouse

12/15-lipoxygenase contributes to retinal inflammation in diabetic retinopathy via activation of ER stress/NADPH oxidase signaling pathway

Endothelial but not Leukocytic 12/15-Lipoxygenase Contributes to Retinal Leukostasis in Diabetic Retinopathy

Adenosine Deaminase-2–Induced Hyperpermeability in Human Retinal Vascular Endothelial Cells Is Suppressed by MicroRNA-146b-3p

Hyperhomocysteinemia Disrupts Retinal Pigment Epithelial Structure and Function with Features of Age-Related Macular Degeneration

Differential Activity of Systemic and Retinal 12/15-Lipoxygenases in a Mouse Model of Diabetes

NOX4 Stabilizes Barrier Function of Human Retinal Endothelial Cells and Retinal Pigment Epithelial Cells

Elevated homocysteine in the vitreous of diabetic patients and blood of type 1 and 2 diabetic animal models; Potential role of homocysteine in blood retinal barrier dysfunction

Exosomes Released From Human Retinal Endothelial Cells Upon 15-HETE Treatment or ER Stress Induction: Potential Role of Nanoparticles in Diabetic Retinopathy

BMP2 and 4 Contribute to Retinal Endothelial Cell Barrier Dysfunction in Diabetic Retinopathy: Role of p38 MAPK Pathway

12/15-Lipoxygenase Gene Deletion Attenuates Blood-Retinal Barrier Dysfunction During Diabetic Retinopathy: Contribution of ER Stress

Supplementing Dietary DHA Attenuates Traumatic Optic Neuropathy by Manipulating 12/15-Lipoxygenase Activity

Pro-inflammatory effect of 12/15-lipoxygenase derived lipid metabolites in retina: Role of Pigment epithelium-derived factor (PEDF) suppression

12/15-Lipoxygenase-Derived Eicosanoids Induce Vascular Inflammation and Angiogenic Effects in Human Retinal Endothelial Cells: Role of NADPH oxidase and ER Stress

Cannabidiol Dampens Streptozotocin-Induced Retinal Inflammation by Targeting of Microglial Activation

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