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Lens April 2022

Patterns of Crystallin Gene Expression in Differentiation State Specific Regions of the Embryonic Chicken Lens

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Zhiwei Ma; Daniel Chauss; Joshua Disatham; Xiaodong Jiao; Lisa Ann Brennan; A. Sue Menko; Marc Kantorow; J. Fielding Hejtmancik
TAGS: crystallins, genes, lens (device), lens, crystalline, chickens, gene expression, embryo
Invest. Ophthalmol. Vis. Sci.. 2022; 63(4):8. doi: https://doi.org/10.1167/iovs.63.4.8

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2021

Perlecan-associated defective epithelial basement membrane regeneration in rabbit corneas after fibrosis-inducing epithelial-stromal injury

Rodrigo Carlos De Oliveira; George Tye; Lycia Sampaio; Thomas Michael Shiju; Marcony R Santhiago; JodiRae DeDreu; A Sue Menko; Steven E Wilson

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):931. doi:

ARVO Annual Meeting Abstract June 2021

Role of PI3K Signaling Inhibition in Inducing Autophagy-Dependent Organelle Elimination

Rifah Gheyas; A Sue Menko

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2084. doi:

ARVO Annual Meeting Abstract June 2021

Uncovering the Properties of Lens Resident Immune Cells

A Sue Menko

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2077. doi:

ARVO Annual Meeting Abstract June 2020

Distinct PI3K Pathways Regulate Elimination of Organelles and Nuclei during Lens Development

Rifah Gheyas; Kelly Ryan; A Sue Menko

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2301. doi:

ARVO Annual Meeting Abstract June 2020

Caspase-Activated DNase (CAD), p27 and Prox1 are Key Downstream Signaling Targets of Caspase-3 in Lens Differentiation Initiation

Kelly Ryan; Rifah Gheyas; A Sue Menko

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2862. doi:

ARVO Annual Meeting Abstract June 2020

In an Experimental Autoimmune Uveitis Model, Immune Cells Populate the Lens Surface-Associated Ciliary Zonules and Transit the Lens Capsule

JodiRae DeDreu; Sonali Pal Ghosh; Paola Parlanti; Mary Mattapallil; Rachel Caspi; Mary Ann Stepp; A Sue Menko

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2863. doi:

ARVO Annual Meeting Abstract June 2020

Lens resident immune cells: mediators of sterile injury and immediate responders to cataract surgery wounding

Janice L Walker; JodiRae DeDreu; Heather Paulson; Caitln Logan; Alex V Levin; A Sue Menko

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):3984. doi:

ARVO Annual Meeting Abstract June 2020

The microenvironment dictates the requirement for endogenous TGFβ signaling in mediating wound healing vs. fibrotic repair in response to injury

Heather Paulson; A Sue Menko; Janice L Walker

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):5035. doi:

ARVO Annual Meeting Abstract July 2019

How the wound-repair microenvironment regulates whether outcomes are regenerative repair or fibrosis

Janice L Walker; A Sue Menko

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):6448. doi:

ARVO Annual Meeting Abstract July 2019

Immune Surveillance of the Lens – Can Protection Lead to Disease?

A Sue Menko; Janice L Walker; JodiRae DeDreu; Caitlin Bowen; Sonali Pal-Ghosh; Mary Ann Stepp

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1380. doi:

ARVO Annual Meeting Abstract July 2019

Genome-wide chromatin mapping and transcriptome analysis reveals chromatin regulation as a novel mechanism for controlling gene expression during lens differentiation

Joshua Disatham; Daniel Chauss; Rifah Gheyas; Lisa A Brennan; David Blanco; Lauren Daley; A Sue Menko; Marc Kantorow

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4286. doi:

ARVO Annual Meeting Abstract June 2017

Elimination of Mitochondria, Endoplasmic Reticulum and Golgi during lens cell differentiation to form the lens organelle-free zone requires the mitophagy protein BNIP3L and is regulated by the transcription factor HIF1a.

Lisa A Brennan; Rebecca McGreal; Caitlin Logan; Ales Cvekl; A Sue Menko; Marc Kantorow

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1212. doi:

ARVO Annual Meeting Abstract June 2017

Lens Fiber Cell Migration and Morphogenesis Depends on N-cadherin Regulation

Caitlin Logan; Suren Rajakaruna; Caitlin Bowen; Glenn Radice; Michael L Robinson; A Sue Menko

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1709. doi:

ARVO Annual Meeting Abstract June 2017

A Critical Role for Microtubules in Lens Morphogenesis Through Regulation of Myosin-II Activation

Caitlin Bowen; Caitlin Logan; A Sue Menko

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1710. doi:

ARVO Annual Meeting Abstract June 2017

A role for the PI3K regulator PIK3IP1 in signaling the autophagy-dependent removal of organelles during lens development

Rifah Gheyas; Lisa A Brennan; Marc Kantorow; A Sue Menko

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1712. doi:

ARVO Annual Meeting Abstract June 2017

α9 Integrin-Vimentin Linked Pathways are Positioned for Important Roles in the Regulation of Wound Healing and Fibrosis

Alhanoof A Alnwibit; Brigid Bleaken; A Sue Menko; Janice L Walker

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):3190. doi:

ARVO Annual Meeting Abstract June 2017

Hyaluronic Acid and its Receptor RHAMM in an Ex Vivo Mock Cataract Surgery Model Under Fibrotic Promoting Conditions

Alison R Romisher; Alhanoof A Alnwibit; William J Vines; Yana Sharpadskaya; A Sue Menko; Janice L Walker

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):3196. doi:

ARVO Annual Meeting Abstract June 2017

Extracellular vimentin secreted in response to injury induces emergence of fibrosis-causing myofibroblasts

Janice L Walker; Alhanoof A Alnwibit; Alison R Romisher; Brigid Bleaken; A Sue Menko

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):3791. doi:

ARVO Annual Meeting Abstract September 2016

Myofibroblast emergence is induced in a PI3K isoform-specific Akt-independent manner in a mock cataract surgery model of PCO

Janice L Walker; Liping Zhang; Tung Chan; A Sue Menko

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12) doi:

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Patterns of Crystallin Gene Expression in Differentiation State Specific Regions of the Embryonic Chicken Lens

Perlecan-associated defective epithelial basement membrane regeneration in rabbit corneas after fibrosis-inducing epithelial-stromal injury

Role of PI3K Signaling Inhibition in Inducing Autophagy-Dependent Organelle Elimination

Uncovering the Properties of Lens Resident Immune Cells

Distinct PI3K Pathways Regulate Elimination of Organelles and Nuclei during Lens Development

Caspase-Activated DNase (CAD), p27 and Prox1 are Key Downstream Signaling Targets of Caspase-3 in Lens Differentiation Initiation

In an Experimental Autoimmune Uveitis Model, Immune Cells Populate the Lens Surface-Associated Ciliary Zonules and Transit the Lens Capsule

Lens resident immune cells: mediators of sterile injury and immediate responders to cataract surgery wounding

The microenvironment dictates the requirement for endogenous TGFβ signaling in mediating wound healing vs. fibrotic repair in response to injury

How the wound-repair microenvironment regulates whether outcomes are regenerative repair or fibrosis

Immune Surveillance of the Lens – Can Protection Lead to Disease?

Genome-wide chromatin mapping and transcriptome analysis reveals chromatin regulation as a novel mechanism for controlling gene expression during lens differentiation

Elimination of Mitochondria, Endoplasmic Reticulum and Golgi during lens cell differentiation to form the lens organelle-free zone requires the mitophagy protein BNIP3L and is regulated by the transcription factor HIF1a.

Lens Fiber Cell Migration and Morphogenesis Depends on N-cadherin Regulation

A Critical Role for Microtubules in Lens Morphogenesis Through Regulation of Myosin-II Activation

A role for the PI3K regulator PIK3IP1 in signaling the autophagy-dependent removal of organelles during lens development

α9 Integrin-Vimentin Linked Pathways are Positioned for Important Roles in the Regulation of Wound Healing and Fibrosis

Hyaluronic Acid and its Receptor RHAMM in an Ex Vivo Mock Cataract Surgery Model Under Fibrotic Promoting Conditions

Extracellular vimentin secreted in response to injury induces emergence of fibrosis-causing myofibroblasts

Myofibroblast emergence is induced in a PI3K isoform-specific Akt-independent manner in a mock cataract surgery model of PCO

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