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ARVO Annual Meeting Abstract June 2021

A human pluripotent stem cell-derived organ-on-a-chip model of the outer blood-retinal barrier for understanding age-related macular degeneration

Yusuf ARIK; Louet Koolen; Sofie ten Brink; Giuliana Gagliardi; Joost Brinks; Seba Almedawar; Camiel Boon; Peter Benz; Heike Neubauer; Stefan Kauschke; Anneke I Den Hollander; Andries van der Meer

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2598. doi:

ARVO Annual Meeting Abstract June 2021

Common and rare genetic risk variants for Age-related Macular Degeneration progression in the Coimbra Eye Study.

Claudia Farinha; Patricia Barreto; Rita Coimbra; Maria Luz Cachulo; Joana Barbosa Melo; Isabel Marques Carreira; Maria Helena Madeira; Anneke I Den Hollander; Carel Hoyng; Jose G Cunha-Vaz; Rufino Silva

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1489. doi:

ARVO Annual Meeting Abstract June 2021

Supplement intake and plasma nutritional biomarkers reduce risk for second eye progression in age-related macular degeneration.

Yara T E Lechanteur; Thomas J Heesterbeek; Anneke I Den Hollander; Laura Lores de Motta; Ilhan E Acar; Eiko K de Jong; B. Jeroen Klevering; Caroline C. W. Klaver; Carel Hoyng

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):347. doi:

ARVO Annual Meeting Abstract June 2021

Genetic characterization of a Portuguese age-related macular degeneration population

Patrícia Barreto; Claudia Farinha; Rita Coimbra; Maria Luz Cachulo; Joana Barbosa Melo; Isabel Marques Carreira; Maria Helena Madeira; Carel Hoyng; Anneke I Den Hollander; Jose G Cunha-Vaz; Rufino Silva

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):310. doi:

ARVO Annual Meeting Abstract June 2021

Downregulation of ABCA1 in iPSC-derived RPE cells impaired cholesterol efflux leading to intracellular lipid accumulation

Florian Peters; David Grubich Atac; Wolfgang Berger; Anneke I Den Hollander; Christian Grimm

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):248. doi:

Genetics December 2020

The Effect of Genetic Variants Associated With Age-Related Macular Degeneration Varies With Age

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Tina Schick; Laura Lorés-Motta; Lebriz Altay; Lars G. Fritsche; Anneke I. den Hollander; Sascha Fauser

Invest. Ophthalmol. Vis. Sci.. 2020; 61(14):17. doi: https://doi.org/10.1167/iovs.61.14.17

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2020

The phenotype of the ARMS2 risk variant in age-related macular degeneration. Findings from the E3 & EYE-RISK consortium

Eric F. Thee; Johanna Colijn; Magda A. Meester; Anneke Den Hollander; Timo Verzijden; Caroline Klaver

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2312. doi:

ARVO Annual Meeting Abstract June 2020

Genotype-phenotype correlation in geographic atrophy secondary to age-related macular degeneration. The EYE-RISK Consortium

Marc Biarnes Perez; Johanna Colijn; Jose Sousa; Lucia Ferraro; Míriam Garcia; Timo Verzijden; Magda A. Meester; Cecile Delcourt; Caroline Klaver; Anneke Den Hollander; Imre Lengyel; Tunde Peto; Jordi Monés

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):3520. doi:

Biochemistry and Molecular Biology May 2020

Genes Involved in Energy Metabolism Are Differentially Expressed During the Day–Night Cycle in Murine Retinal Pigment Epithelium

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Elja M. M. Louer; Guoqiang Yi; Claudia Carmone; Joris Robben; Henk G. Stunnenberg; Anneke I. den Hollander; Peter M. T. Deen
TAGS: genes, mice, rhythm, metabolism, retinal pigment epithelium, energy metabolism, sequence analysis, rna
Invest. Ophthalmol. Vis. Sci.. 2020; 61(5):49. doi: https://doi.org/10.1167/iovs.61.5.49

Includes: Supplemental Content

Retina March 2020

Complement Activation Levels Are Related to Disease Stage in AMD

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Thomas J. Heesterbeek; Yara T. E. Lechanteur; Laura Lorés-Motta; Tina Schick; Mohamed R. Daha; Lebriz Altay; Sandra Liakopoulos; Dzenita Smailhodzic; Anneke I. den Hollander; Carel B. Hoyng; Eiko K. de Jong; B. Jeroen Klevering
TAGS: complement activation, complement system proteins, choroidal neovascularization
Invest. Ophthalmol. Vis. Sci.. 2020; 61(3):18. doi: https://doi.org/10.1167/iovs.61.3.18

Includes: Supplemental Content

Retina August 2019

Elevated Steroid Hormone Levels in Active Chronic Central Serous Chorioretinopathy

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Rosa L. Schellevis; Lebriz Altay; Asha Kalisingh; Timo W. F. Mulders; Vasilena Sitnilska; Carel B. Hoyng; Camiel J. F. Boon; Joannes M. M. Groenewoud; Eiko K. de Jong; Anneke I. den Hollander
TAGS: central serous chorioretinopathy, steroid hormone, steroids, hormones
Invest. Ophthalmol. Vis. Sci.. 2019; 60(10):3407-3413. doi: https://doi.org/10.1167/iovs.19-26781

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2019

Metabolomics in Age-related Macular Degeneration: The EYE-RISK Consortium

Ilhan Erkin Acar; Magda Meester; Laura Lorés de Motta; Daniel Pauleikhoff; Sascha Fauser; Carel C B Hoyng; Cecile DelCourt; Caroline C W Klaver; Tessel E Galesloot; Anneke I Den Hollander

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1004. doi:

ARVO Annual Meeting Abstract July 2019

Risk factors for Fellow Eye Progression in Patients with Unilateral Exudative Age-Related Macular Degeneration

Julia Lemke; Vasilena Sitnilska; Caroline Gietzelt; Tina Schick; Carel C B Hoyng; Anneke I Den Hollander; Sascha Fauser; Lebriz Altay

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1134. doi:

ARVO Annual Meeting Abstract July 2019

Non-genetic risk factors for age-related macular degeneration in nonagenarians

Vasilena Sitnilska; Tina Schick; Anneke I Den Hollander; Carel C B Hoyng; Sascha Fauser; Lebriz Altay

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1135. doi:

ARVO Annual Meeting Abstract July 2019

Expression levels of rare missense variants in CFI found in age-related macular degeneration, atypical uremic syndrome or both diseases

Sarah de Jong; Elena Volokhina; Sara Nilsson; Bjorn Bakker; Eiko de Jong; Lambert van den Heuvel; Anna Blom; Anneke I Den Hollander

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4914. doi:

ARVO Annual Meeting Abstract July 2019

Development of a Genotyping Assay for Age-Related Macular Degeneration: The EYE-RISK Consortium

Anita de Breuk; Ilhan Erkin Acar; Magda Meester; Mascha MVAP Schijvenaars; Eveline Kersten; Jordi Mones; Daniel Pauleikhoff; Rufino Silva; Sascha Fauser; Carel C B Hoyng; Cecile DelCourt; Caroline C W Klaver; Marieke JH Coenen; Anneke I Den Hollander

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2955. doi:

ARVO Annual Meeting Abstract July 2019

Subclinical choroidal neovascularizations in fellow-eyes of exudative age-related macular degeneration patients show a decrease in retinal sensitivity over time

Thomas Johannes Heesterbeek; Yara Lechanteur; Anita de Breuk; Anneke I Den Hollander; Jeroen Klevering; Thomas Theelen; Carel C B Hoyng

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3484. doi:

ARVO Annual Meeting Abstract July 2019

Factor H-Related Protein 4 (FHR-4) drives complement dysregulation in age-related macular degeneration

Valentina Cipriani; Laura Lorés de Motta; Fan He; Dina Fathalla; Selina McHarg; Nadhim Bayatti; Ilhan Erkin Acar; Carel C B Hoyng; Sascha Fauser; Anthony Moore; John RW Yates; Paul Morgan; Eiko de Jong; Anneke I Den Hollander; Paul N Bishop; Simon J Clark

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3870. doi:

ARVO Annual Meeting Abstract July 2019

Whole genome methylation profiling of retinal pigment epithelium reveals differential methylation and gene expression associated with AMD

Louise Frances Porter; Neil Saptarshi; Yongxiang Fang; Sonika Rathi; Anneke I Den Hollander; Eiko de Jong; Simon Clark; Paul N Bishop; Timothy W Olsen; Triantafillos Liloglu; Venkata Ramana Murthy Chavali; Luminita Paraoan

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4247. doi:

ARVO Annual Meeting Abstract July 2019

The effect of genetic variants associated with age-related macular degeneration decreases in individuals aged 90 years and older. Findings from the International AMD Genomics Consortium

Laura Lorés de Motta; Tina Schick; Lebriz Altay; Carel C B Hoyng; Anneke I Den Hollander; Sascha Fauser

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4248. doi:

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A human pluripotent stem cell-derived organ-on-a-chip model of the outer blood-retinal barrier for understanding age-related macular degeneration

Common and rare genetic risk variants for Age-related Macular Degeneration progression in the Coimbra Eye Study.

Supplement intake and plasma nutritional biomarkers reduce risk for second eye progression in age-related macular degeneration.

Genetic characterization of a Portuguese age-related macular degeneration population

Downregulation of ABCA1 in iPSC-derived RPE cells impaired cholesterol efflux leading to intracellular lipid accumulation

The Effect of Genetic Variants Associated With Age-Related Macular Degeneration Varies With Age

The phenotype of the ARMS2 risk variant in age-related macular degeneration. Findings from the E3 & EYE-RISK consortium

Genotype-phenotype correlation in geographic atrophy secondary to age-related macular degeneration. The EYE-RISK Consortium

Genes Involved in Energy Metabolism Are Differentially Expressed During the Day–Night Cycle in Murine Retinal Pigment Epithelium

Complement Activation Levels Are Related to Disease Stage in AMD

Elevated Steroid Hormone Levels in Active Chronic Central Serous Chorioretinopathy

Metabolomics in Age-related Macular Degeneration: The EYE-RISK Consortium

Risk factors for Fellow Eye Progression in Patients with Unilateral Exudative Age-Related Macular Degeneration

Non-genetic risk factors for age-related macular degeneration in nonagenarians

Expression levels of rare missense variants in CFI found in age-related macular degeneration, atypical uremic syndrome or both diseases

Development of a Genotyping Assay for Age-Related Macular Degeneration: The EYE-RISK Consortium

Subclinical choroidal neovascularizations in fellow-eyes of exudative age-related macular degeneration patients show a decrease in retinal sensitivity over time

Factor H-Related Protein 4 (FHR-4) drives complement dysregulation in age-related macular degeneration

Whole genome methylation profiling of retinal pigment epithelium reveals differential methylation and gene expression associated with AMD

The effect of genetic variants associated with age-related macular degeneration decreases in individuals aged 90 years and older. Findings from the International AMD Genomics Consortium

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