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Glaucoma November 2020

Reduced Oxidative Phosphorylation and Increased Glycolysis in Human Glaucoma Lamina Cribrosa Cells

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Khalid Kamel; Colm J. O'Brien; Alexander V. Zhdanov; Dmitri B. Papkovsky; Abbot F. Clark; W. Daniel Stamer; Mustapha Irnaten

Invest. Ophthalmol. Vis. Sci.. 2020; 61(13):4. doi: https://doi.org/10.1167/iovs.61.13.4

ARVO Annual Meeting Abstract June 2020

The mechanical rigidity of the extracellular matrix regulates the structure, proliferation and stiffness of human trabecular meshwork cells

Sarah Eivers; Baiyun Liu; Jason Kilpatrick; Bartlomiej Lukasz; Suzanne Jarvis; Abbot F Clark; Deborah Wallace; Colm J O'Brien

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):3457. doi:

ARVO Annual Meeting Abstract July 2019

Gene delivery to the trabecular meshwork for target validation, development of disease models, and the treatment of glaucoma

Abbot F Clark

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1038. doi:

ARVO Annual Meeting Abstract July 2019

The role of cadherins in glaucomatous trabecular signaling and the regulation of IOP

Abbot F Clark

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1365. doi:

ARVO Annual Meeting Abstract July 2019

The Role of Yes-Associated Protein (YAP) in Mechanotransduction at the Lamina Cribrosa and its Potential as a Novel Therapeutic Target In Glaucoma.

Rory Murphy; Alan Hopkins; Mustapha Irnaten; W Daniel Stamer; Abbot F Clark; Deirdre Brennan; Deborah Wallace; Colm J O'Brien

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1786. doi:

ARVO Annual Meeting Abstract July 2019

Evidence of Increased Glycolysis and Glutaminolysis in Glaucoma Lamina Cribrosa Cells

Mustapha Irnaten; Diarmaid Hickey; Deirdre Brennan; William D Stamer; Abbot F Clark; Colm J O'Brien

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5650. doi:

ARVO Annual Meeting Abstract July 2019

Characterization of gene expression profiles of cultured human primary trabecular meshwork cells, transformed cell lines and human skin fibroblasts

Ankur Jain; Tasneem Putliwala Sharma; S. Scott whitmore; Todd E Scheetz; Abbot F Clark; Budd Tucker; John H Fingert

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5664. doi:

ARVO Annual Meeting Abstract July 2019

TGFβ2 Regulation of DNMTs in Optic Nerve Head Astrocytes

Tara Tovar-Vidales; Navita Lopez; Abbot F Clark

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5667. doi:

ARVO Annual Meeting Abstract July 2019

Epigenetic regulation of optic nerve head fibrosis in glaucoma

Navita Lopez; Abbot F Clark; Tara Tovar-Vidales

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5668. doi:

ARVO Annual Meeting Abstract July 2019

Canonical Wnt signaling in optic nerve head astrocytes

Declan Ilan Hesson; Yang Liu; Abbot F Clark

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5671. doi:

ARVO Annual Meeting Abstract July 2019

Piezo1 plays a role in optic nerve head astrocyte mechanotransduction

Yang Liu; Jiafeng Liu; Abbot F Clark; Yong Yang

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):6185. doi:

ARVO Annual Meeting Abstract July 2019

Modulating human intraocular and intracranial pressure using the ex-vivo Translaminar Autonomous System

Tasneem Putliwala Sharma; Abbot F Clark; Husain Lohawala; Colleen M McDowell

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2247. doi:

Glaucoma May 2019

Glucocorticoid Receptor Transactivation Is Required for Glucocorticoid-Induced Ocular Hypertension and Glaucoma

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Gaurang C. Patel; J. Cameron Millar; Abbot F. Clark
TAGS: glaucoma, glucocorticoid receptors, glucocorticoids, medication therapy management, mice, ocular hypertension, trans-activation (genetics), intraocular pressure, injections
Invest. Ophthalmol. Vis. Sci.. 2019; 60(6):1967-1978. doi: https://doi.org/10.1167/iovs.18-26383

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2018

Mouse Eye Perfusion In-Vivo Versus Ex-Vivo: Influence on Aqueous Outflow Facility

J Cameron Millar; Navita N Lopez; Urmimala Raychaudhuri; Abbot F. Clark

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1655. doi:

ARVO Annual Meeting Abstract July 2018

TGFβ2 regulates the expression of ECM and associated proteins by modulating miRNAs in human optic nerve head astrocytes and lamina cribrosa cells

Navita Nanda Lopez; Tara Tovar-Vidales; Abbot F. Clark

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3524. doi:

ARVO Annual Meeting Abstract July 2018

High glucose impairs optic nerve head astrocyte phagocytosis prior to retinal ganglion cell degeneration

Yang Liu; Jinzi Wu; Liang-jun Yan; Abbot F. Clark

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3549. doi:

ARVO Annual Meeting Abstract July 2018

Canonical Wnt signaling in optic nerve head

Elliott Allums; Yang Liu; Abbot F. Clark

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3739. doi:

ARVO Annual Meeting Abstract July 2018

Primary Cilia and Extracellular Matrix Interactions in Trabecular Meshwork Cells

Ankur Jain; Wei Zhu; Qihong Zhang; Markus H Kuehn; Abbot F. Clark; Val C. Sheffield

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):4721. doi:

ARVO Annual Meeting Abstract July 2018

Glucocorticoid-Induced Ocular Hypertension in Mice Requires Glucocorticoid Receptor Transactivation Activity

Abbot F. Clark; J Cameron Millar; Gaurang Patel

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):6037. doi:

ARVO Annual Meeting Abstract July 2018

Novel Ex-Vivo Translaminar Autonomous System to study effects of Intraocular and Intracranial pressure differential on Human Retinal Ganglion Cells.

Tasneem Putliwala Sharma; Abbot F. Clark; Colleen M McDowell

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1214. doi:

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Reduced Oxidative Phosphorylation and Increased Glycolysis in Human Glaucoma Lamina Cribrosa Cells

The mechanical rigidity of the extracellular matrix regulates the structure, proliferation and stiffness of human trabecular meshwork cells

Gene delivery to the trabecular meshwork for target validation, development of disease models, and the treatment of glaucoma

The role of cadherins in glaucomatous trabecular signaling and the regulation of IOP

The Role of Yes-Associated Protein (YAP) in Mechanotransduction at the Lamina Cribrosa and its Potential as a Novel Therapeutic Target In Glaucoma.

Evidence of Increased Glycolysis and Glutaminolysis in Glaucoma Lamina Cribrosa Cells

Characterization of gene expression profiles of cultured human primary trabecular meshwork cells, transformed cell lines and human skin fibroblasts

TGFβ2 Regulation of DNMTs in Optic Nerve Head Astrocytes

Epigenetic regulation of optic nerve head fibrosis in glaucoma

Canonical Wnt signaling in optic nerve head astrocytes

Piezo1 plays a role in optic nerve head astrocyte mechanotransduction

Modulating human intraocular and intracranial pressure using the ex-vivo Translaminar Autonomous System

Glucocorticoid Receptor Transactivation Is Required for Glucocorticoid-Induced Ocular Hypertension and Glaucoma

Mouse Eye Perfusion In-Vivo Versus Ex-Vivo: Influence on Aqueous Outflow Facility

TGFβ2 regulates the expression of ECM and associated proteins by modulating miRNAs in human optic nerve head astrocytes and lamina cribrosa cells

High glucose impairs optic nerve head astrocyte phagocytosis prior to retinal ganglion cell degeneration

Canonical Wnt signaling in optic nerve head

Primary Cilia and Extracellular Matrix Interactions in Trabecular Meshwork Cells

Glucocorticoid-Induced Ocular Hypertension in Mice Requires Glucocorticoid Receptor Transactivation Activity

Novel Ex-Vivo Translaminar Autonomous System to study effects of Intraocular and Intracranial pressure differential on Human Retinal Ganglion Cells.

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