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ARVO Annual Meeting Abstract June 2024

ALDH1A1 Gene Therapy Attenuates Acrolein-Induced Müller Cell Dysfunction in Diabetic Retinopathy.

Burak Mugdat Karan; Josy Augustine; Peter Barabas; Mei Chen; Alan W Stitt; Tim M Curtis

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):872.

ARVO Annual Meeting Abstract June 2023

The impact of forced circadian misalignment on the progression of diabetic retinopathy

Hanagh Winter; Katie Dunlop; Thomas Friedel; Josy Augustine; Tim M Curtis; Alan Stitt; Eleni Beli

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):939.

ARVO Annual Meeting Abstract June 2023

Exploring the vasoreparative function of the APC/EPCR pathway in diabetic retinopathy

Amie Lowry; Elisa Peixoto; Sarah Chambers; Reinhold Medina; Alan Stitt; Judith Lechner

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):573.

ARVO Annual Meeting Abstract June 2023

Gene therapeutic enhancement of acrolein detoxification mechanisms for the treatment of diabetic retinopathy

Burak Mugdat Karan; Josy Augustine; Peter Barabas; Mei Chen; Alan W Stitt; Tim M Curtis

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):998.

ARVO Annual Meeting Abstract June 2023

Longitudinal study of neurovascular and glial pathology in the streptozotocin-induced rat model of diabetic retinopathy

Josy Augustine; Rosemary E McDowell; Thomas Friedel; Paul Canning; Alan W Stitt; Tim M Curtis

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):1601.

ARVO Annual Meeting Abstract June 2022

"Mapping in time" the daily rhythmic transcriptome in the diabetic retina

Eleni Beli; Ryan P Silk; Hanagh R Winter; Vijay Tiwari; David Simpson; Alan W Stitt

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):281 – F0326.

ARVO Annual Meeting Abstract June 2022

Characterising retinal neurovascular dysfunction in a mouse model of Alzheimer’s disease combined with Type 2 diabetes

Karis Little; María Llorián-Salvador; Ángel del Marco; Monica Garcia-Alloza; Rafael Simó; Alan W Stitt

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):271 – F0316.

ARVO Annual Meeting Abstract June 2022

Regulatory T cells limit age-associated retinal degeneration

Maria Llorian-Salvador; Alerie Guzman de la Fuente; Alan W Stitt; Denise Fitzgerald

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):963 – A0432.

ARVO Annual Meeting Abstract June 2022

Circadian rhythms in diabetic retinal endothelial cells

Hanagh Winter; Andriana Margariti; Alan W Stitt; Eleni Beli

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):790 – F0349.

ARVO Annual Meeting Abstract June 2022

THR-687, a potent pan-RGD integrin antagonist, protects against retinal vascular permeability, inflammation and reactive gliosis in the diabetic rat

Tine Van Bergen; Astrid De Vriese; Bart Jonckx; Kelly Vanhulst; Marc Vanhove; Michaël Porcu; Elke Vermassen; Philippe Barbeaux; Alan W Stitt

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2306.

ARVO Annual Meeting Abstract June 2022

2-Hydrazino-4,6-dimethylpyrimidine (2-HDP) as a novel therapeutic for the neurovascular pathology of diabetic retinopathy

Josy Augustine; Evan P Troendle; Thomas Friedel; Eimear M Byrne; Paul Canning; Peter Barabas; Martin B Ulmschneider; Alan W Stitt; Tim M Curtis

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2305.

ARVO Annual Meeting Abstract June 2022

Deletion of Angiotensin II type 2 receptor (AT2) exacerbates retinal neovascularization and hemorrhage in oxygen-induced retinopathy (OIR)

Kevin Harkin; Pietro Bertelli; Hazal Yilmaz; Paul Canning; Ana Rodriguez; Thomas Walther; Alan W Stitt

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2677.

Retina October 2021

Targeting Plasma Kallikrein With a Novel Bicyclic Peptide Inhibitor (THR-149) Reduces Retinal Thickening in a Diabetic Rat Model

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Tine Van Bergen; Tjing-Tjing Hu; Karis Little; Lies De Groef; Lieve Moons; Alan W. Stitt; Elke Vermassen; Jean H. M. Feyen
TAGS: diabetes mellitus, plasma kallikrein, eye, peptides
Invest. Ophthalmol. Vis. Sci.. 2021; 62(13):18. https://doi.org/10.1167/iovs.62.13.18

ARVO Annual Meeting Abstract June 2021

The role of the EPCR pathway in protecting endogenous repair cells in the choriocapillaris

Elisa Peixoto; Sarah Chambers; Stuart McKeown; Lynsey-Dawn Allen; Pietro Bertelli; Reinhold J. Medina; Alan Stitt

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):259.

ARVO Annual Meeting Abstract June 2021

Exposure to a diabetic-like milieu in vitro alters metabolism in human microvascular endothelial cells

David Hughes; Pietro Bertelli; Edoardo Pedrini; Cristina Branco; Tim Curtis; Reinhold J. Medina; Alan Stitt

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2252.

ARVO Annual Meeting Abstract June 2021

The role of placental growth factor (PlGF) in retinal pigment epithelial (RPE) barrier integrity and outer retinal integrity in geographic atrophy

Fiona Cunningham; Tine van Bergen; Jean Feyen; Imre Lengyel; Alan Stitt

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2698.

ARVO Annual Meeting Abstract June 2021

Regenerating the ocular retinal vasculature using endothelial progenitors is modulated by miR-130

Stuart McKeown; Jasenka Guduric-Fuchs; Reinhold J. Medina; Alan Stitt

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):3021.

Physiology and Pharmacology August 2019

Involvement of TRPV1 and TRPV4 Channels in Retinal Angiogenesis

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Caitriona O'Leary; Mary K. McGahon; Sadaf Ashraf; Jennifer McNaughten; Thomas Friedel; Patrizia Cincolà; Peter Barabas; Jose A. Fernandez; Alan W. Stitt; J. Graham McGeown; Tim M. Curtis
TAGS: angiogenesis, trpv1 receptor
Invest. Ophthalmol. Vis. Sci.. 2019; 60(10):3297-3309. https://doi.org/10.1167/iovs.18-26344

Includes: Multimedia, Supplemental Content

ARVO Annual Meeting Abstract July 2019

Pre-treatment of Endothelial Colony Forming Cells (ECFCs) with a novel anti-oxidant enhances their vasoregenerative potential.

Stuart McKeown; Paul Canning; Caroline Barelle; Fiona Cunningham; Donald McPhail; Andrew J.R Porter; Reinhold J. Medina; Alan W Stitt

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1663.

ARVO Annual Meeting Abstract July 2019

Placental growth factor (PlGF) induced signalling regulates barrier properties of the retinal pigment epithelium (RPE)

Fiona Cunningham; Paul Canning; Tine Van Bergen; Jean Feyen; Imre Lengyel; Alan W Stitt

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1932.

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ALDH1A1 Gene Therapy Attenuates Acrolein-Induced Müller Cell Dysfunction in Diabetic Retinopathy.

The impact of forced circadian misalignment on the progression of diabetic retinopathy

Exploring the vasoreparative function of the APC/EPCR pathway in diabetic retinopathy

Gene therapeutic enhancement of acrolein detoxification mechanisms for the treatment of diabetic retinopathy

Longitudinal study of neurovascular and glial pathology in the streptozotocin-induced rat model of diabetic retinopathy

"Mapping in time" the daily rhythmic transcriptome in the diabetic retina

Characterising retinal neurovascular dysfunction in a mouse model of Alzheimer’s disease combined with Type 2 diabetes

Regulatory T cells limit age-associated retinal degeneration

Circadian rhythms in diabetic retinal endothelial cells

THR-687, a potent pan-RGD integrin antagonist, protects against retinal vascular permeability, inflammation and reactive gliosis in the diabetic rat

2-Hydrazino-4,6-dimethylpyrimidine (2-HDP) as a novel therapeutic for the neurovascular pathology of diabetic retinopathy

Deletion of Angiotensin II type 2 receptor (AT2) exacerbates retinal neovascularization and hemorrhage in oxygen-induced retinopathy (OIR)

Targeting Plasma Kallikrein With a Novel Bicyclic Peptide Inhibitor (THR-149) Reduces Retinal Thickening in a Diabetic Rat Model

The role of the EPCR pathway in protecting endogenous repair cells in the choriocapillaris

Exposure to a diabetic-like milieu in vitro alters metabolism in human microvascular endothelial cells

The role of placental growth factor (PlGF) in retinal pigment epithelial (RPE) barrier integrity and outer retinal integrity in geographic atrophy

Regenerating the ocular retinal vasculature using endothelial progenitors is modulated by miR-130

Involvement of TRPV1 and TRPV4 Channels in Retinal Angiogenesis

Pre-treatment of Endothelial Colony Forming Cells (ECFCs) with a novel anti-oxidant enhances their vasoregenerative potential.

Placental growth factor (PlGF) induced signalling regulates barrier properties of the retinal pigment epithelium (RPE)

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