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Retina July 2022

The Relationship Between Fetal Growth and Retinal Nerve Fiber Layer Thickness in a Cohort of Young Adults

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Kathleen I. C. Dyer; Paul G. Sanfilippo; Seyhan Yazar; Jamie E. Craig; Alex W. Hewitt; John P. Newnham; David A. Mackey; Samantha S. Y. Lee
TAGS: cohort studies, fetal growth, retinal nerve fiber layer, young adult, pregnancy, birth weight, fetus
Trans. Vis. Sci. Tech.. 2022; 11(7):8. doi: https://doi.org/10.1167/tvst.11.7.8

Includes: Supplemental Content

Genetics June 2022

Sonic Hedgehog Intron Variant Associated With an Unusual Pediatric Cortical Cataract

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Terri L. Young; Kristina N. Whisenhunt; Sarah M. LaMartina; Alex W. Hewitt; David A. Mackey; Stuart W. Tompson
TAGS: cataract, childhood, cortical cataract, introns, pediatrics, shh gene, enhancer of transcription, genes, genetic pedigree
Invest. Ophthalmol. Vis. Sci.. 2022; 63(6):25. doi: https://doi.org/10.1167/iovs.63.6.25

ARVO Annual Meeting Abstract June 2022

The APOE E4 allele is associated with faster rates of mGCIPL thinning in the PROGRESSA cohort

Sean Mullany; Henry Marshall; Emmanuelle Souzeau; Mark Hassall; Ashish Agar; Anna Galanopoulos; John Landers; Paul Mitchell; Paul Healey; Stuart L Graham; Alex W Hewitt; Stuart MacGregor; Puya Gharahkhani; Robert Casson; Owen Siggs; Jamie E Craig

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):1658 – A0153. doi:

ARVO Annual Meeting Abstract June 2022

Change in peripapillary retinal nerve fibre layer thickness from 20 to 28 years old

Samantha Sze-Yee Lee; Alex W Hewitt; David A Mackey

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):1629 – A0124. doi:

ARVO Annual Meeting Abstract June 2022

Investigating photoreceptor outer segment phagocytosis by retinal pigment epithelium in CLN3-Batten

Jimin Han; Katherine A White; Sueanne Chear; Jana Talbot; Whitney Spencer; Cheyenne I Thomas; Vicki Swier Mosher; Tyler B Johnson; Alex W Hewitt; Anthony L Cook; Jill M Weimer; Ruchira Singh

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2442 – F0386. doi:

ARVO Annual Meeting Abstract June 2022

High polygenic risk is associated with earlier treatment initiation and escalation in glaucoma suspects

Henry Marshall; Xikun Han; Sean Mullany; Georgie Hollitt; Ella Claire Berry; Lachlan Knight; Richard A Mills; John Landers; Paul Healey; Alex W Hewitt; Stuart L Graham; Robert Casson; Stuart MacGregor; Owen Siggs; Jamie E Craig

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):4018 – A0360. doi:

ARVO Annual Meeting Abstract June 2022

A polygenic risk score predicts functional progression in early primary open-angle glaucoma

Owen Siggs; Ayub Qassim; Xikun Han; Henry Marshall; Sean Mullany; Emmanuelle Souzeau; Anna Galanopoulos; Ashish Agar; John Landers; Robert Casson; Alex W Hewitt; Paul Healey; Stuart L Graham; Stuart MacGregor; Jamie Craig

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):4011 – A0353. doi:

ARVO Annual Meeting Abstract June 2022

Generation of a CRISPRi RPE model to study age-related macular degeneration genetics

Raymond Wong; Jiang Hui Wang; Daniel Urrutia-Cabrera; Jarmon Lees; Santiago Mesa Mora; Tu Nguyen; Sandy Shen-Chi Hung; Alex W Hewitt; Thomas Edwards

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):4607 – F0399. doi:

ARVO Annual Meeting Abstract June 2022

Genetic biomarkers predicting response to anti-vascular endothelial growth factor injections in diabetic macular edema, a pilot study

Rajya L gurung; Liesel M FitzGerald; Bennet J McComish; ebony lui; Jamie E Craig; Nitin Verma; Alex W Hewitt; Brendan JT Vote; Kathryn P Burdon

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3852. doi:

ARVO Annual Meeting Abstract June 2021

Intronic variant in sonic hedgehog associated with autosomal dominant pediatric cataract, myopic astigmatism, familial exudative vitreoretinopathy, and primary open-angle glaucoma

Stuart W. Tompson; Kristina N. Whisenhunt; Alex W Hewitt; David A Mackey; Terri L Young

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):5. doi:

ARVO Annual Meeting Abstract June 2021

Cost-effectiveness of polygenic risk profiling for primary open-angle glaucoma in the United Kingdom and Australia

Qinqin Liu; John Davis; Xikun Han; David A Mackey; Stuart MacGregor; Jamie E Craig; Lei Si; Alex W Hewitt

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2649. doi:

ARVO Annual Meeting Abstract June 2021

The relationship between fetal growth and retinal nerve fibre layer thickness measured in a cohort of young adults

Kathleen Dyer; Seyhan Yazar; Paul Sanfilippo; John Newnham; Jamie E Craig; Alex W Hewitt; David A Mackey; Samantha SY Lee

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1583. doi:

ARVO Annual Meeting Abstract June 2021

Combining glaucoma and correlated risk factors dramatically expands gene discovery for glaucoma

Stuart MacGregor; Xikun Han; Puya Gharahkhani; Maciej Trzaskowski; Jamie E Craig; Alex W Hewitt; David A Mackey; Janey L Wiggs; Anthony P Khawaja

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1512. doi:

ARVO Annual Meeting Abstract June 2021

Hypercholestolaemia predicts disease progression in primary open-angle glaucoma

Henry Marshall; Sean Mullany; Ayub Qassim; Xikun Han; Mark Hassall; Thi Nguyen; Paul R Healey; Ashish Agar; Alex W Hewitt; Stuart MacGregor; Stuart L Graham; Robert Casson; Owen Siggs; Jamie E Craig

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2365. doi:

ARVO Annual Meeting Abstract June 2020

Towards retinal regeneration: Reprogramming retinal glial cells into photoreceptors using CRISPRa

Raymond Wong; Tu Nguyen; Lyujie Fang; Sam Lukowski; Camden Lo; Sandy Hung; Chi D Luu; Mark C Gillies; Alex W Hewitt

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2497. doi:

ARVO Annual Meeting Abstract June 2020

A polygenic risk score predicts intraocular pressure fluctuation and readings outside office hours as measured by home tonometry

Ayub Qassim; Mona S Awadalla; Sean Mullany; Mark Hassall; owen siggs; Emmanuelle Souzeau; Thi Nguyen; Henry Marshall; Xikun Han; Angela Schulz; Anna Galanopoulos; Stuart L Graham; Alex W Hewitt; Stuart MacGregor; John Landers; Jamie E Craig

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):3491. doi:

Genetics September 2019

MicroRNA-Related Genetic Variants Are Associated With Diabetic Retinopathy in Type 1 Diabetes Mellitus

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Ebony Liu; Georgia Kaidonis; Bennet J. McComish; Mark C. Gillies; Sotoodeh Abhary; Rohan W. Essex; John H. Chang; Bishwanath Pal; Mark Daniell; Stewart Lake; Nikolai Petrovsky; Alex W. Hewitt; Alicia Jenkins; Ecosse L. Lamoureux; Jonathan M. Gleadle; Jamie E. Craig; Kathryn P. Burdon
TAGS: diabetes mellitus, type 1, diabetic retinopathy, genes, genetics, micrornas, single nucleotide polymorphism
Invest. Ophthalmol. Vis. Sci.. 2019; 60(12):3937-3942. doi: https://doi.org/10.1167/iovs.18-25570

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2019

A glaucoma polygenic risk score strongly associated with disease prediction and treatment intensity.

Jamie E Craig; Ayub Qassim; Xikun Han; Mark Hassall; Robert James Casson; Stuart L Graham; David A Mackey; Colin Willoughby; Kathryn P Burdon; John Landers; Emmanuelle Souzeau; Janey L Wiggs; Alex W Hewitt; Stuart MacGregor

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1619. doi:

ARVO Annual Meeting Abstract July 2019

Associations between optic disc measures and obstructive sleep apnoea in young adults

Samantha SY Lee; Nigel McArdle; Paul Sanfilippo; Seyhan Yazar; Peter Eastwood; Alex W Hewitt; David A Mackey

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1957. doi:

ARVO Annual Meeting Abstract July 2019

The correlation between Glaucoma polygenic risk score and IOP measured by Icare® HOME tonometry within and outside of office hours.

Mona S Awadalla; Mark Hassall; Ayub Qassim; thi thi nguyen; Xikun Han; Stuart MacGregor; John Landers; Jamie E Craig; David A Mackey; Alex W Hewitt

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2408. doi:

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The Relationship Between Fetal Growth and Retinal Nerve Fiber Layer Thickness in a Cohort of Young Adults

Sonic Hedgehog Intron Variant Associated With an Unusual Pediatric Cortical Cataract

The APOE E4 allele is associated with faster rates of mGCIPL thinning in the PROGRESSA cohort

Change in peripapillary retinal nerve fibre layer thickness from 20 to 28 years old

Investigating photoreceptor outer segment phagocytosis by retinal pigment epithelium in CLN3-Batten

High polygenic risk is associated with earlier treatment initiation and escalation in glaucoma suspects

A polygenic risk score predicts functional progression in early primary open-angle glaucoma

Generation of a CRISPRi RPE model to study age-related macular degeneration genetics

Genetic biomarkers predicting response to anti-vascular endothelial growth factor injections in diabetic macular edema, a pilot study

Intronic variant in sonic hedgehog associated with autosomal dominant pediatric cataract, myopic astigmatism, familial exudative vitreoretinopathy, and primary open-angle glaucoma

Cost-effectiveness of polygenic risk profiling for primary open-angle glaucoma in the United Kingdom and Australia

The relationship between fetal growth and retinal nerve fibre layer thickness measured in a cohort of young adults

Combining glaucoma and correlated risk factors dramatically expands gene discovery for glaucoma

Hypercholestolaemia predicts disease progression in primary open-angle glaucoma

Towards retinal regeneration: Reprogramming retinal glial cells into photoreceptors using CRISPRa

A polygenic risk score predicts intraocular pressure fluctuation and readings outside office hours as measured by home tonometry

MicroRNA-Related Genetic Variants Are Associated With Diabetic Retinopathy in Type 1 Diabetes Mellitus

A glaucoma polygenic risk score strongly associated with disease prediction and treatment intensity.

Associations between optic disc measures and obstructive sleep apnoea in young adults

The correlation between Glaucoma polygenic risk score and IOP measured by Icare® HOME tonometry within and outside of office hours.

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