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Glaucoma May 2024

TGFβ Signaling Dysregulation May Contribute to COL4A1-Related Glaucomatous Optic Nerve Damage

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Mao Mao; Yien-Ming Kuo; Alfred K. Yu; Cassandre Labelle-Dumais; Yvonne Ou; Douglas B. Gould
TAGS: glaucoma, mice, optic nerve, signal transduction, transforming growth factor-beta type ii receptor, heterozygote, eye, intraocular pressure
Invest. Ophthalmol. Vis. Sci.. 2024; 65(5):15. https://doi.org/10.1167/iovs.65.5.15

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2022

Retinal ex vivo live imaging indicates microglia interaction with synaptic sites in experimental glaucoma

Tonatiuh Garcia Ruiz; Alfred K Yu; Jeanette Hyer; Luca Della Santina; Yvonne Ou

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):10.

ARVO Annual Meeting Abstract June 2022

Thrombospondin-1 is synaptoprotective in a retina explant model

Alan W Kong; Tonatiuh Garcia Ruiz; Yien-Ming Kuo; Alfred K Yu; Luca Della Santina; Yvonne Ou

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):1618 – A0441.

ARVO Annual Meeting Abstract June 2021

Activated microglia target specific ganglion cell types in experimental glaucoma

Alfred K Yu; Luca Della Santina; Manuel Soliño; Yvonne Ou

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2349.

ARVO Annual Meeting Abstract June 2021

Rearrangement of retinal inhibitory and excitatory synapses in experimental glaucoma

Luca Della Santina; Manuel Soliño; Tonatiuh Garcia-Ruiz; Alfred K Yu; Yvonne Ou

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):3144.

ARVO Annual Meeting Abstract June 2021

Expanding the view: large-scale assessment of synaptic disassembly in experimental glaucoma

Manuel Soliño; Alfred K Yu; Luca Della Santina; Yvonne Ou

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):3137.

ARVO Annual Meeting Abstract June 2020

Microglial activation in experimental glaucoma is mediated by complement signaling

Alfred K Yu; Luca Della Santina; Kelly Mai; Yvonne Ou

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):270.

ARVO Annual Meeting Abstract July 2019

Microglial activation and interaction at synaptic sites in experimental glaucoma.

Alfred K Yu; Kelly Mai; Esther Choe; Alan Tran; Luca Della Santina; Yvonne Ou

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):672.

ARVO Annual Meeting Abstract July 2019

Disassembly and rewiring of synaptic connectivity in the inner retina in experimental glaucoma

Yvonne Ou; Alfred K Yu; Kelly Mai; Alan Tran; Luca Della Santina

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):6440.

ARVO Annual Meeting Abstract September 2016

Repurposing known drugs to identify potential therapeutics for Leber's hereditary Optic Neuropathy: screening in cells and testing in a mouse model of LHON.

Gino Cortopassi; Alfred K Yu; Sandipan Datta; Lanying Song

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):763.

ARVO Annual Meeting Abstract September 2016

Protection of visual function and neurodegeneration in a mouse model of Leber’s hereditary optic neuropathy by drug intervention

Alfred K Yu; Lanying Song; Sandipan Datta; Gino Cortopassi

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):6409.

Retina June 2016

Epithelial Membrane Protein-2 in Human Proliferative Vitreoretinopathy and Epiretinal Membranes

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David G. Telander; Alfred K. Yu; Krisztina I. Forward; Shawn A. Morales; Lawrence S. Morse; Susanna S. Park; Lynn K. Gordon
TAGS: epiretinal membrane, epithelium, proteins, tissue membrane, vitreoretinopathy, proliferative, immunohistochemistry
Invest. Ophthalmol. Vis. Sci.. 2016; 57(7):3112-3117. https://doi.org/10.1167/iovs.15-17791

ARVO Annual Meeting Abstract June 2015

Leber's hereditary Optic Neuropathy: cellular pathophysiology, potential animal model, and cell-based drug screens for potential therapeutics

Gino Cortopassi; Alfred K Yu; Lanying Song; Karl Murray

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):3858.

ARVO Annual Meeting Abstract June 2015

Rapamycin rescues the innate immune/inflammatory response in the retina of the Ndufs4 mouse

Alfred K Yu; Lanying Song; Karl Murray; Gino Cortopassi

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):5541.

ARVO Annual Meeting Abstract April 2014

Microglial activation and inflammatory response in a mouse model of Leber’s Hereditary Optic Neuropathy

Alfred K Yu; Lanying Song; Karl D Murray; Deborah van der List; Gino A Cortopassi

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):1352.

Retina March 2013

The Comparative Histologic Effects of Subthreshold 532- and 810-nm Diode Micropulse Laser on the Retina

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Alfred K. Yu; Kevin D. Merrill; Steven N. Truong; Krisztina M. Forward; Lawrence S. Morse; David G. Telander
TAGS: lasers, retina, light coagulation
Invest. Ophthalmol. Vis. Sci.. 2013; 54(3):2216-2224. https://doi.org/10.1167/iovs.12-11382

ARVO Annual Meeting Abstract March 2012

Dasatinib inhibits experimental PVR progression

Shawn A. Morales; David G. Telander; Alfred K. Yu; Krisztina I. Forward; Jonathan Braun; Lynn K. Gordon

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):899.

ARVO Annual Meeting Abstract March 2012

Age-related Variation of Cytosine Methylation in the Sod2 Promoter in the RPE/choroid and Retina Within and Among Individual BALB/c Mouse Eyes

Leonard M. Hjelmeland; Alfred K. Yu; Zeljka Smit-McBride

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):5136.

ARVO Annual Meeting Abstract March 2012

Ocular Safety of Dasatinib in a Rabbit Model

Alfred K. Yu; Shawn A. Morales; Krisztina I. Forward; Lynn K. Gordon; David G. Telander

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):5357.

ARVO Annual Meeting Abstract March 2012

Analysis And Comparison Of Human Circulatory MicroRNA Profiles Of Aqueous And Vitreous Humour From Normal Eyes vs. Those With Diabetic Retinopathy or AMD

Zeljka Smit-McBride; Saadia Rashid; Alfred K. Yu; Susanna S. Park; Leonard M. Hjelmeland; David G. Telander; Lawrence S. Morse

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):2438.

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TGFβ Signaling Dysregulation May Contribute to COL4A1-Related Glaucomatous Optic Nerve Damage

Retinal ex vivo live imaging indicates microglia interaction with synaptic sites in experimental glaucoma

Thrombospondin-1 is synaptoprotective in a retina explant model

Activated microglia target specific ganglion cell types in experimental glaucoma

Rearrangement of retinal inhibitory and excitatory synapses in experimental glaucoma

Expanding the view: large-scale assessment of synaptic disassembly in experimental glaucoma

Microglial activation in experimental glaucoma is mediated by complement signaling

Microglial activation and interaction at synaptic sites in experimental glaucoma.

Disassembly and rewiring of synaptic connectivity in the inner retina in experimental glaucoma

Repurposing known drugs to identify potential therapeutics for Leber's hereditary Optic Neuropathy: screening in cells and testing in a mouse model of LHON.

Protection of visual function and neurodegeneration in a mouse model of Leber’s hereditary optic neuropathy by drug intervention

Epithelial Membrane Protein-2 in Human Proliferative Vitreoretinopathy and Epiretinal Membranes

Leber's hereditary Optic Neuropathy: cellular pathophysiology, potential animal model, and cell-based drug screens for potential therapeutics

Rapamycin rescues the innate immune/inflammatory response in the retina of the Ndufs4 mouse

Microglial activation and inflammatory response in a mouse model of Leber’s Hereditary Optic Neuropathy

The Comparative Histologic Effects of Subthreshold 532- and 810-nm Diode Micropulse Laser on the Retina

Dasatinib inhibits experimental PVR progression

Age-related Variation of Cytosine Methylation in the Sod2 Promoter in the RPE/choroid and Retina Within and Among Individual BALB/c Mouse Eyes

Ocular Safety of Dasatinib in a Rabbit Model

Analysis And Comparison Of Human Circulatory MicroRNA Profiles Of Aqueous And Vitreous Humour From Normal Eyes vs. Those With Diabetic Retinopathy or AMD

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