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Biochemistry and Molecular Biology December 2015

Modulating the Transport Characteristics of Bruch's Membrane With Steroidal Glycosides and its Relevance to Age-Related Macular Degeneration (AMD)

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Yunhee Lee; Ali A. Hussain; Jae-Hwan Seok; Suhn-Hee Kim; John Marshall
TAGS: biological transport, bruch's basal membrane, panax, lipids, glycosides
Invest. Ophthalmol. Vis. Sci.. 2015; 56(13):8403-8418. doi: https://doi.org/10.1167/iovs.15-16936

ARVO Annual Meeting Abstract April 2014

The effect of varying levels of active MMP on hydraulic conductivity across aged Bruch’s membrane.

Ling Zhi Heng; Ali A Hussain; John Marshall

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):1320. doi:

ARVO Annual Meeting Abstract April 2014

Developing phosphotidyl choline polymers for ocular implantation

Athmar Dhahir Habeeb; Alastair Lockwood; Ali A Hussain; Jin H Wang; Mike Driver; Steve Brocchini; Peng Khaw

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):477. doi:

Glaucoma April 2014

Characterization of the Gelatinase System of the Laminar Human Optic Nerve, and Surrounding Annulus of Bruch's Membrane, Choroid, and Sclera

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Ali A. Hussain; Yunhee Lee; Jin-Jun Zhang; John Marshall
TAGS: bruch's basal membrane, choroid, gelatinases, matrix metalloproteinases, optic nerve, sclera, proteins
Invest. Ophthalmol. Vis. Sci.. 2014; 55(4):2358-2364. doi: https://doi.org/10.1167/iovs.13-12503

ARVO Annual Meeting Abstract June 2013

Vectorial release of matrix metalloproteinase enzymes from porcine RPE in explant culture following nanosecond laser exposure

Ling Zhi Heng; Ali Hussain; Sobha Sivaprasad; Robin Hamilton; John Marshall

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):1382. doi:

Translational Research May 2012

Laser-Mediated Activation of Human Retinal Pigment Epithelial Cells and Concomitant Release of Matrix Metalloproteinases

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Jin Jun Zhang; Yue Sun; Ali A. Hussain; John Marshall
TAGS: laser therapy, lasers, matrix metalloproteinases, retinal pigment cell
Invest. Ophthalmol. Vis. Sci.. 2012; 53(6):2928-2937. doi: https://doi.org/10.1167/iovs.11-8585

ARVO Annual Meeting Abstract March 2012

Characterisation Of The Gelatinase Component Of The Matrix Metalloproteinase (MMP) System At The Human Optic Nerve Head Region

Ali A. Hussain; Yunhee Lee; JinJun Zhang; John Marshall

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):3859. doi:

ARVO Annual Meeting Abstract March 2012

Laser Mediated Activation Of Human Retinal Pigment Epithelial (rpe) Cells And Concomitant Release Of Matrix Metalloproteinases (mmps)

JinJun Zhang; Ali Hussain; John Marshall

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):5817. doi:

ARVO Annual Meeting Abstract March 2012

Characterisation Of The Large Macromolecular MMP Complex Of Human Bruch’s Membrane With Respect To Stability, Activation And Effects Of Ginseng Compounds

Yong Dol Shin; Jae Hwan Seok; Cheul Muu Sim; Min Young Kang; Hyeon Jea Shim; Yun Hee Lee; Ali Hussain

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):6486. doi:

ARVO Annual Meeting Abstract March 2012

Ginseng Mediated Improvement In The Hydraulic Conductivity Of Human Bruch’s Membrane: Potential For Preventive Therapy In AMD

Cheul Muu Sim; Jae Hwan Seok; Min Young Kang; Yong Dol Shin; Hyeon Jea Shim; Yun Hee Lee; Ali Hussain

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):6494. doi:

ARVO Annual Meeting Abstract March 2012

Effect Of Divalent Metal Chelation On The MMP System And Transport Characteristics Of Human Bruch’s Membrane

Yunhee Lee; Ali Hussain; John Marshall

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):6500. doi:

ARVO Annual Meeting Abstract March 2012

Albumin Diffusion Across Human Bruch’s Membrane: Modulation By Ginseng Compounds

Min Young Kang; Cheul Muu Sim; Jae Hwan Seok; Yong Dol Shin; Hyeon Jae Shim; Yun Hee Lee; Ali Hussain

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):1595. doi:

Anatomy and Pathology/Oncology June 2011

Disturbed Matrix Metalloproteinase Activity of Bruch's Membrane in Age-Related Macular Degeneration

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Ali A. Hussain; Yunhee Lee; Jin-Jun Zhang; John Marshall
TAGS: age-related macular degeneration, bruch's basal membrane, donors, gelatinase a, gelatinase b, gelatinases, matrix metalloproteinases, gel
Invest. Ophthalmol. Vis. Sci.. 2011; 52(7):4459-4466. doi: https://doi.org/10.1167/iovs.10-6678

Biochemistry and Molecular Biology May 2010

High Molecular-Weight Gelatinase Species of Human Bruch's Membrane: Compositional Analyses and Age-Related Changes

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Ali A. Hussain; Yunhee Lee; John Marshall
TAGS: bruch's basal membrane, gelatinases, molecular mass, gelatinase a, gelatinase b
Invest. Ophthalmol. Vis. Sci.. 2010; 51(5):2363-2371. doi: https://doi.org/10.1167/iovs.09-4259

Retina May 2010

Increased Sequestration of Matrix Metalloproteinases in Ageing Human Bruch's Membrane: Implications for ECM Turnover

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Anupma Kumar; Austen El-Osta; Ali A. Hussain; John Marshall
TAGS: aging, bruch's basal membrane, matrix metalloproteinases, gelatinases, gelatinase a, donors
Invest. Ophthalmol. Vis. Sci.. 2010; 51(5):2664-2670. doi: https://doi.org/10.1167/iovs.09-4195

Retina November 2008

Scleral Hydraulic Conductivity and Macromolecular Diffusion in Patients with Uveal Effusion Syndrome

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Timothy L. Jackson; Ali Hussain; Ana M. S. Morley; Paul M. Sullivan; Andrea Hodgetts; Austen El-Osta; Jost Hillenkamp; Stephen J. Charles; Richard Sheard; Tom H. Williamson; Anupma Kumar; D. Alistair H. Laidlaw; W. Hong Woon; Mark J. Costen; Andrew J. Luff; John Marshall
TAGS: diffusion, effusion, sclera, syndrome, uvea, surgical procedures, operative, dextran
Invest. Ophthalmol. Vis. Sci.. 2008; 49(11):5033-5040. doi: https://doi.org/10.1167/iovs.08-1980

Includes: Supplemental Content

Physiology and Pharmacology September 2008

Human Transscleral Albumin Permeability and the Effect of Topographical Location and Donor Age

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Owen A. Anderson; Timothy L. Jackson; Jasmin K. Singh; Ali A. Hussain; John Marshall
TAGS: albumins, donors, permeability, sclera
Invest. Ophthalmol. Vis. Sci.. 2008; 49(9):4041-4045. doi: https://doi.org/10.1167/iovs.07-1660

Physiology and Pharmacology November 2006

Human Scleral Hydraulic Conductivity: Age-Related Changes, Topographical Variation, and Potential Scleral Outflow Facility

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Timothy L. Jackson; Ali Hussain; Andrea Hodgetts; Ana M. S. Morley; Jost Hillenkamp; Paul M. Sullivan; John Marshall
TAGS: sclera
Invest. Ophthalmol. Vis. Sci.. 2006; 47(11):4942-4946. doi: https://doi.org/10.1167/iovs.06-0362

Retina December 2004

Taurine Uptake by Human Retinal Pigment Epithelium: Implications for the Transport of Small Solutes between the Choroid and the Outer Retina

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Jost Hillenkamp; Ali A. Hussain; Timothy L. Jackson; Joanna R. Cunningham; John Marshall
TAGS: biological transport, choroid, taurine, retina, retinal pigment epithelium
Invest. Ophthalmol. Vis. Sci.. 2004; 45(12):4529-4534. doi: https://doi.org/10.1167/iovs.04-0919

Physiology and Pharmacology November 2004

Compartmental Analysis of Taurine Transport to the Outer Retina in the Bovine Eye

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Jost Hillenkamp; Ali A. Hussain; Timothy L. Jackson; Paul A. Constable; Joanna R. Cunningham; John Marshall
TAGS: biological transport, taurine, cattle, mass or substance concentration per volume, retina, choroid
Invest. Ophthalmol. Vis. Sci.. 2004; 45(11):4099-4105. doi: https://doi.org/10.1167/iovs.04-0624

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Modulating the Transport Characteristics of Bruch's Membrane With Steroidal Glycosides and its Relevance to Age-Related Macular Degeneration (AMD)

The effect of varying levels of active MMP on hydraulic conductivity across aged Bruch’s membrane.

Developing phosphotidyl choline polymers for ocular implantation

Characterization of the Gelatinase System of the Laminar Human Optic Nerve, and Surrounding Annulus of Bruch's Membrane, Choroid, and Sclera

Vectorial release of matrix metalloproteinase enzymes from porcine RPE in explant culture following nanosecond laser exposure

Laser-Mediated Activation of Human Retinal Pigment Epithelial Cells and Concomitant Release of Matrix Metalloproteinases

Characterisation Of The Gelatinase Component Of The Matrix Metalloproteinase (MMP) System At The Human Optic Nerve Head Region

Laser Mediated Activation Of Human Retinal Pigment Epithelial (rpe) Cells And Concomitant Release Of Matrix Metalloproteinases (mmps)

Characterisation Of The Large Macromolecular MMP Complex Of Human Bruch’s Membrane With Respect To Stability, Activation And Effects Of Ginseng Compounds

Ginseng Mediated Improvement In The Hydraulic Conductivity Of Human Bruch’s Membrane: Potential For Preventive Therapy In AMD

Effect Of Divalent Metal Chelation On The MMP System And Transport Characteristics Of Human Bruch’s Membrane

Albumin Diffusion Across Human Bruch’s Membrane: Modulation By Ginseng Compounds

Disturbed Matrix Metalloproteinase Activity of Bruch's Membrane in Age-Related Macular Degeneration

High Molecular-Weight Gelatinase Species of Human Bruch's Membrane: Compositional Analyses and Age-Related Changes

Increased Sequestration of Matrix Metalloproteinases in Ageing Human Bruch's Membrane: Implications for ECM Turnover

Scleral Hydraulic Conductivity and Macromolecular Diffusion in Patients with Uveal Effusion Syndrome

Human Transscleral Albumin Permeability and the Effect of Topographical Location and Donor Age

Human Scleral Hydraulic Conductivity: Age-Related Changes, Topographical Variation, and Potential Scleral Outflow Facility

Taurine Uptake by Human Retinal Pigment Epithelium: Implications for the Transport of Small Solutes between the Choroid and the Outer Retina

Compartmental Analysis of Taurine Transport to the Outer Retina in the Bovine Eye

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