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Glaucoma February 2018

Testosterone Pathway Genetic Polymorphisms in Relation to Primary Open-Angle Glaucoma: An Analysis in Two Large Datasets

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Jessica N. Cooke Bailey; Puya Gharahkhani; Jae H. Kang; Mariusz Butkiewicz; David A. Sullivan; Robert N. Weinreb; Hugues Aschard; R. Rand Allingham; Allison Ashley-Koch; Richard K. Lee; Sayoko E. Moroi; Murray H. Brilliant; Gadi Wollstein; Joel S. Schuman; John H. Fingert; Donald L. Budenz; Tony Realini; Terry Gaasterland; William K. Scott; Kuldev Singh; Arthur J. Sit; Robert P. Igo, Jr; Yeunjoo E. Song; Lisa Hark; Robert Ritch; Douglas J. Rhee; Douglas Vollrath; Donald J. Zack; Felipe Medeiros; Thasarat S. Vajaranant; Daniel I. Chasman; William G. Christen; Margaret A. Pericak-Vance; Yutao Liu; Peter Kraft; Julia E. Richards; Bernard A. Rosner; Michael A. Hauser; Jamie E. Craig; Kathryn P. Burdon; Alex W. Hewitt; David A. Mackey; Jonathan L. Haines; Stuart MacGregor; Janey L. Wiggs; Louis R. Pasquale; for the Australian and New Zealand Registry of Advanced Glaucoma (ANZRAG) Consortium
TAGS: testosterone, metabolism, polymorphism, glaucoma, genes, open-angle glaucoma, datasets
Invest. Ophthalmol. Vis. Sci.. 2018; 59(2):629-636. doi: 10.1167/iovs.17-22708

Includes: Supplemental Content

Genetics March 2017

Systematic Functional Testing of Rare Variants: Contributions of CFI to Age-Related Macular Degeneration

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Perciliz L. Tan; Melanie E. Garrett; Jason R. Willer; Peter A. Campochiaro; Betsy Campochiaro; Donald J. Zack; Allison E. Ashley-Koch; Nicholas Katsanis
TAGS: alleles, cohort studies, age-related macular degeneration, cultural formulation interview
Invest. Ophthalmol. Vis. Sci.. 2017; 58(3):1570-1576. doi: 10.1167/iovs.16-20867

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2015

Interval mapping reveals a quantitative trait locus controlling retinal ganglion cell number in mice

Felix L Struebing; Rebecca King; Allison Ashley-Koch; Michael A Hauser; R Rand Allingham; Eldon E Geisert

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):3660. doi:

ARVO Annual Meeting Abstract June 2015

GENOMIC LOCI MODULATING GANGLION CELL DEATH FOLLOWING ELEVATED IOP IN THE MOUSE

Eldon E Geisert; Felix L Struebing; Rebecca King; Louis R Pasquale; Allison E Ashley-Koch; Michael A Hauser; R Rand Allingham; Janey L Wiggs

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):3665. doi:

ARVO Annual Meeting Abstract June 2015

Mouse Genomic Loci Modulating Corneal Thickness

Rebecca King; Michael A Hauser; Louis R Pasquale; Janey L Wiggs; Allison E Ashley-Koch; R Rand Allingham; Eldon E Geisert

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):1645. doi:

Genetics December 2014

DNA Copy Number Variants of Known Glaucoma Genes in Relation to Primary Open-Angle Glaucoma

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Yutao Liu; Melanie E. Garrett; Brian L. Yaspan; Jessica Cooke Bailey; Stephanie J. Loomis; Murray Brilliant; Donald L. Budenz; William G. Christen; John H. Fingert; Douglas Gaasterland; Terry Gaasterland; Jae H. Kang; Richard K. Lee; Paul Lichter; Sayoko E. Moroi; Anthony Realini; Julia E. Richards; Joel S. Schuman; William K. Scott; Kuldev Singh; Arthur J. Sit; Douglas Vollrath; Robert Weinreb; Gadi Wollstein; Donald J. Zack; Kang Zhang; Margaret A. Pericak-Vance; Jonathan L. Haines; Louis R. Pasquale; Janey L. Wiggs; R. Rand Allingham; Allison E. Ashley-Koch; Michael A. Hauser
TAGS: glaucoma, dna, genes, open-angle glaucoma, copy number polymorphism
Invest. Ophthalmol. Vis. Sci.. 2014; 55(12):8251-8258. doi: 10.1167/iovs.14-15712

ARVO Annual Meeting Abstract April 2014

The retinal nerve fiber layer is reduced in POAG cases homozygous for the common Six6 risk-allele of rs33912345 (Asn141His)

Shane J Havens; Joanne C Wen; Megan Ulmer Carnes; Janey L Wiggs; Louis R Pasquale; Allison E Ashley-Koch; Michael A Hauser; R Rand Allingham; NEIGHBORHOOD Consortium Investigators

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):3799. doi:

ARVO Annual Meeting Abstract April 2014

Rare Genetic Variants are Associated with POAG in Populations of African Ancestry

Michael A Hauser; Allison E Ashley-Koch; Xuejun Qin; Shelby Strickland; Yutao Liu; Christopher A Girkin; Donald L Budenz; Stephen Akafo; R. Rand Allingham; ICAARE-Glaucoma Consortium

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):3807. doi:

ARVO Annual Meeting Abstract April 2014

Copy Number Variants associated with Glaucoma in the NEIGHBOR Study

Allison E Ashley-Koch; Melanie E Garrett; Jonathan L Haines; Janey L Wiggs; Louis R Pasquale; Yutao Liu; R Rand Allingham; Michael A Hauser; NEIGHBORHOOD Consortium Investigators

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):3814. doi:

ARVO Annual Meeting Abstract April 2014

Variants associated with exfoliation glaucoma affect promoter activity of the LOXL1 antisense gene

Inas F Aboobakar; Yutao Liu; Shiro Miura; Joshua Wheeler; Xuejun Qin; Megan Ulmer Carnes; Benjamin T Whigham; Allison E Ashley-Koch; Michael A Hauser; R. Rand Allingham

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):3816. doi:

Glaucoma September 2013

Gene Expression Profile in Human Trabecular Meshwork From Patients With Primary Open-Angle Glaucoma

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Yutao Liu; R. Rand Allingham; Xuejun Qin; David Layfield; Andrew E. Dellinger; Jason Gibson; Joshua Wheeler; Allison E. Ashley-Koch; W. Daniel Stamer; Michael A. Hauser
TAGS: gene expression profiling, open-angle glaucoma, trabecular meshwork, myoc gene
Invest. Ophthalmol. Vis. Sci.. 2013; 54(9):6382-6389. doi: 10.1167/iovs.13-12128

Includes: Supplemental Content

Genetics September 2013

Investigation of Known Genetic Risk Factors for Primary Open Angle Glaucoma in Two Populations of African Ancestry

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Yutao Liu; Michael A. Hauser; Stephen K. Akafo; Xuejun Qin; Shiroh Miura; Jason R. Gibson; Joshua Wheeler; Douglas E. Gaasterland; Pratap Challa; Leon W. Herndon; Robert Ritch; Sayoko E. Moroi; Louis R. Pasquale; Christopher A. Girkin; Donald L. Budenz; Janey L. Wiggs; Julia E. Richards; Allison E. Ashley-Koch; R. Rand Allingham
TAGS: glaucoma, open-angle glaucoma, single nucleotide polymorphism, genetic risk, african american, cdkn2b gene
Invest. Ophthalmol. Vis. Sci.. 2013; 54(9):6248-6254. doi: 10.1167/iovs.13-12779

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2013

The role of SIX6 in primary open-angle glaucoma

Michael Hauser; Megan Ulmer; Yangfan Liu; Erica Davis; Nicholas Katsanis; Yutao Liu; Louis Pasquale; Janey Wiggs; Allison Ashley-Koch; R Rand Allingham; NEIGHBORHOOD Consortium Investigators

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):4501. doi:

ARVO Annual Meeting Abstract June 2013

The Role of Protein-Coding Variants in South Africans with Exfoliation Glaucoma

Yutao Liu; Xuejun Qin; Jason Gibson; Susan Williams; Robyn Rautenbach; Trevor Carmichael; Allison Ashley-Koch; R Rand Allingham; Michael Hauser

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):6229. doi:

ARVO Annual Meeting Abstract June 2013

Rare Genetic Variants in African Americans with Primary Open Angle Glaucoma

Allison Ashley-Koch; Xuejun Qin; Jason Gibson; Yutao Liu; Janey Wiggs; Julia Richards; Sayoko Moroi; Christopher Girkin; R Rand Allingham; Michael Hauser; POAG African American Study Group

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):6239. doi:

Genetics July 2012

Genome-Wide Analysis of Central Corneal Thickness in Primary Open-Angle Glaucoma Cases in the NEIGHBOR and GLAUGEN Consortia

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Megan Ulmer; Jun Li; Brian L. Yaspan; Ayse Bilge Ozel; Julia E. Richards; Sayoko E. Moroi; Felicia Hawthorne; Donald L. Budenz; David S. Friedman; Douglas Gaasterland; Jonathan Haines; Jae H. Kang; Richard Lee; Paul Lichter; Yutao Liu; Louis R. Pasquale; Margaret Pericak-Vance; Anthony Realini; Joel S. Schuman; Kuldev Singh; Douglas Vollrath; Robert Weinreb; Gadi Wollstein; Donald J. Zack; Kang Zhang; Terri Young; R. Rand Allingham; Janey L. Wiggs; Allison Ashley-Koch; Michael A. Hauser
TAGS: open-angle glaucoma, cornea, genome-wide association study
Invest. Ophthalmol. Vis. Sci.. 2012; 53(8):4468-4474. doi: 10.1167/iovs.12-9784

Includes: Supplemental Content

ARVO Annual Meeting Abstract March 2012

Genome-wide Analysis Of Central Corneal Thickness In POAG Cases From The NEIGHBOR Consortium

Megan Ulmer; Jun Li; Ayse B. Ozel; Julia Richards; Sayoko E. Moroi; Brian Yaspan; Janey L. Wiggs; Allison Ashley-Koch; NEIGHBOR Consortium Investigators; Michael A. Hauser

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):5291. doi:

ARVO Annual Meeting Abstract March 2012

Gene Expression Profiling Of Human Trabecular Meshwork In Glaucoma Patients With Or Without Myocilin Mutations

Yutao Liu; Xuejun Qin; David Layfield; Andrew E. Dellinger; Jason Gibson; Joshua Wheeler; Allison E. Ashley-Koch; W Daniel Stamer; Michael A. Hauser; R R. Allingham

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):3844. doi:

ARVO Annual Meeting Abstract March 2012

POAG Genetic Risk Factors In The African American and West African Populations

R R. Allingham; Yutao Liu; Jason Gibson; Joshua Wheeler; Xuejun Qin; Christopher A. Girkin; Stephen K. Akafo; Allison E. Ashley-Koch; POAG African American Study Group; Michael A. Hauser

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):4496. doi:

ARVO Annual Meeting Abstract March 2012

Identification of Candidate Regulatory Variants in Exfoliation Glaucoma

Allison E. Ashley-Koch; Yutao Liu; Susan E. Williams; Benjamin Whigham; Joshua Wheeler; Trevor R. Carmichael; Xuejun Qin; Pratap Challa; R R. Allingham; Michael A. Hauser

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):4506. doi:

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Testosterone Pathway Genetic Polymorphisms in Relation to Primary Open-Angle Glaucoma: An Analysis in Two Large Datasets

Systematic Functional Testing of Rare Variants: Contributions of CFI to Age-Related Macular Degeneration

Interval mapping reveals a quantitative trait locus controlling retinal ganglion cell number in mice

GENOMIC LOCI MODULATING GANGLION CELL DEATH FOLLOWING ELEVATED IOP IN THE MOUSE

Mouse Genomic Loci Modulating Corneal Thickness

DNA Copy Number Variants of Known Glaucoma Genes in Relation to Primary Open-Angle Glaucoma

The retinal nerve fiber layer is reduced in POAG cases homozygous for the common Six6 risk-allele of rs33912345 (Asn141His)

Rare Genetic Variants are Associated with POAG in Populations of African Ancestry

Copy Number Variants associated with Glaucoma in the NEIGHBOR Study

Variants associated with exfoliation glaucoma affect promoter activity of the LOXL1 antisense gene

Gene Expression Profile in Human Trabecular Meshwork From Patients With Primary Open-Angle Glaucoma

Investigation of Known Genetic Risk Factors for Primary Open Angle Glaucoma in Two Populations of African Ancestry

The role of SIX6 in primary open-angle glaucoma

The Role of Protein-Coding Variants in South Africans with Exfoliation Glaucoma

Rare Genetic Variants in African Americans with Primary Open Angle Glaucoma

Genome-Wide Analysis of Central Corneal Thickness in Primary Open-Angle Glaucoma Cases in the NEIGHBOR and GLAUGEN Consortia

Genome-wide Analysis Of Central Corneal Thickness In POAG Cases From The NEIGHBOR Consortium

Gene Expression Profiling Of Human Trabecular Meshwork In Glaucoma Patients With Or Without Myocilin Mutations

POAG Genetic Risk Factors In The African American and West African Populations

Identification of Candidate Regulatory Variants in Exfoliation Glaucoma

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