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Cornea July 2024

Physiological Effects of Soat1 Inactivation on Homeostasis of the Mouse Ocular Surface

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Amber Wilkerson; Seher Yuksel; Riya Acharya; Igor A. Butovich
TAGS: cornea, mice, ocular surfaces
Invest. Ophthalmol. Vis. Sci.. 2024; 65(8):2. https://doi.org/10.1167/iovs.65.8.2

Includes: Supplemental Content

Cornea August 2023

Comparative Biophysical Study of Meibomian Lipids of Wild Type and Soat1 -Null Mice: Implications to Meibomian Gland Dysfunction and Dry Eye Disease

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Xiaojie Xu; Amber Wilkerson; Guangle Li; Igor A. Butovich; Yi Y. Zuo
TAGS: dry eye syndromes, lipids, meibomian gland dysfunction, mice, biophysics
Invest. Ophthalmol. Vis. Sci.. 2023; 64(11):20. https://doi.org/10.1167/iovs.64.11.20

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2023

Retinoic acid receptor X alpha mutant strain develops meibomian gland disease with aging

Ebru Yaman; Igor A Butovich; Jahan Alam; Amber Wilkerson; Ghasem Yasdanpanah; Stephen C Pflugfelder

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):171.

ARVO Annual Meeting Abstract June 2023

Comparative Biophysical Study of Meibomian Lipids of Wild Type and Soat1- Knockout Mice: Implications to Dry Eye

Yi Zuo; Xiaojie Xu; Amber Wilkerson; Igor A Butovich

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):188.

ARVO Annual Meeting Abstract June 2023

Sdr16c5 and Sdr16c6 genes control a bifurcation point between meibogenesis and sebogenesis in Meibomian glands of mice by suppressing a dormant biosynthetic pathway

Igor A Butovich; Amber Wilkerson; Kelly R. Goggans; Natalia Kedishvili; Seher Yuksel

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):166.

ARVO Annual Meeting Abstract June 2023

Hedgehog signaling and lipid synthesis during Meibomian gland development and homeostasis in mouse and human

Carlo Iomini; Céline Portal; Varuni Rastogi; Yvonne Lin; Amber Wilkerson; Igor A Butovich

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):693.

ARVO Annual Meeting Abstract June 2023

Investigating the impact of Soat1 inactivation on the mouse ocular phenotype

Amber Wilkerson; Igor A Butovich

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):3019.

ARVO Annual Meeting Abstract June 2022

Pathophysiological consequences of Soat1/ SOAT1 inactivation for the ocular surface and Meibomian gland homeostasis

Amber Wilkerson; Igor A Butovich

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2271.

ARVO Annual Meeting Abstract June 2021

Sterol O-acyltransferase 1 ( Soat1 ) is critical for cholesteryl ester production in mouse Meibomian glands

Amber Wilkerson; Seher Yuksel; Igor A Butovich

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2048.

ARVO Annual Meeting Abstract June 2021

Establishing the role of dietary lipids in meibogenesis

Seher Yuksel; Amber Wilkerson; Igor A Butovich

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):704.

ARVO Annual Meeting Abstract June 2020

The roles of Elovl3 and Elovl4 in lipid homeostasis in Harderian glands of mice

Seher Yuksel; Amber Wilkerson; Anne McMahon; Igor A Butovich

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2622.

ARVO Annual Meeting Abstract June 2020

Inactivation of Awat2 in mice causes loss of wax ester lipids from meibum.

Anne McMahon; Seher Yuksel; Nita Bhat; Hai Pham; Amber Wilkerson; Igor A Butovich

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2632.

ARVO Annual Meeting Abstract June 2020

Elongases of very long chain fatty acids-3 and 4 (ELOVL3 and ELOVL4) are essential for biosynthesis of meibum in mice

Amber Wilkerson; Nita Bhat; Seher Yuksel; Anne McMahon; Hai Pham; Igor A Butovich

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):3227.

ARVO Annual Meeting Abstract July 2019

Side-by-side comparison of branching and elongation patterns of cholesteryl esters of human and mouse meibum

Seher Yuksel; Nita Bhat; Amber Wilkerson; Anne McMahon; Jadwiga Wojtowicz; Igor A Butovich

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4175.

ARVO Annual Meeting Abstract July 2019

Elongase of Very Long Chain Fatty Acids-3 (Elovl3) Is Critical for Meibum Biosynthesis in Mice

Amber Wilkerson; Nita Bhat; Anne McMahon; Igor A Butovich

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4194.

ARVO Annual Meeting Abstract July 2019

Defining the Role of ELOVL6 in Meibogenesis in Mice

Anne McMahon; Seher Yuksel; Amber Wilkerson; Nita Bhat; Igor A Butovich

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4302.

Immunology and Microbiology September 2018

Induction of Contrasuppressor Cells and Loss of Immune Privilege Produced by Corneal Nerve Ablation

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Sudha Neelam; Jessamee Mellon; Amber Wilkerson; Jerry Y. Niederkorn
TAGS: cornea, eye, immune privilege, mice, nerve ablation, injections, adoptive transfer, patient isolation, spleen, immunization
Invest. Ophthalmol. Vis. Sci.. 2018; 59(11):4738-4747. https://doi.org/10.1167/iovs.18-24894

ARVO Annual Meeting Abstract July 2018

Severing corneal nerves induces the release of substance P which converts ocular surface CD11c+ cells to contrasuppressor cells that abolish ocular immune privilege.

Sudha Neelam; Amber Wilkerson; Jessamee Mellon; Jerry Y Niederkorn

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):2576.

ARVO Annual Meeting Abstract June 2017

Corneal nerve ablation in one eye induces Langerhans cell infiltration into both eyes and abolishes immune privilege in both eyes

Jerry Y Niederkorn; Juan Mo; Sudha neelam; jessamee Mellon; amber Wilkerson

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):5731.

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Physiological Effects of Soat1 Inactivation on Homeostasis of the Mouse Ocular Surface

Comparative Biophysical Study of Meibomian Lipids of Wild Type and Soat1 -Null Mice: Implications to Meibomian Gland Dysfunction and Dry Eye Disease

Retinoic acid receptor X alpha mutant strain develops meibomian gland disease with aging

Comparative Biophysical Study of Meibomian Lipids of Wild Type and Soat1- Knockout Mice: Implications to Dry Eye

Sdr16c5 and Sdr16c6 genes control a bifurcation point between meibogenesis and sebogenesis in Meibomian glands of mice by suppressing a dormant biosynthetic pathway

Hedgehog signaling and lipid synthesis during Meibomian gland development and homeostasis in mouse and human

Investigating the impact of Soat1 inactivation on the mouse ocular phenotype

Pathophysiological consequences of Soat1/ SOAT1 inactivation for the ocular surface and Meibomian gland homeostasis

Sterol O-acyltransferase 1 ( Soat1 ) is critical for cholesteryl ester production in mouse Meibomian glands

Establishing the role of dietary lipids in meibogenesis

The roles of Elovl3 and Elovl4 in lipid homeostasis in Harderian glands of mice

Inactivation of Awat2 in mice causes loss of wax ester lipids from meibum.

Elongases of very long chain fatty acids-3 and 4 (ELOVL3 and ELOVL4) are essential for biosynthesis of meibum in mice

Side-by-side comparison of branching and elongation patterns of cholesteryl esters of human and mouse meibum

Elongase of Very Long Chain Fatty Acids-3 (Elovl3) Is Critical for Meibum Biosynthesis in Mice

Defining the Role of ELOVL6 in Meibogenesis in Mice

Induction of Contrasuppressor Cells and Loss of Immune Privilege Produced by Corneal Nerve Ablation

Severing corneal nerves induces the release of substance P which converts ocular surface CD11c+ cells to contrasuppressor cells that abolish ocular immune privilege.

Corneal nerve ablation in one eye induces Langerhans cell infiltration into both eyes and abolishes immune privilege in both eyes

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