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ARVO Annual Meeting Abstract June 2015

Weekly oral delivery of a vascular endothelial growth factor receptor (VEGFR) inhibitor compound optimized for ocular exposure improves safety and maintains efficacy compared to daily dosing

Yubin Qiu; Siyuan Shen; Elizabeth S Fassbender; Amber Woolfenden; Debby Long; Ron Newton; Erik Meredith; Bruce D Jaffee; Stephen H Poor; Ophthalmology, Novartis Institutes for BioMedical Research, Inc.

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):151. doi:

ARVO Annual Meeting Abstract June 2015

A vascular endothelial growth factor receptor inhibitor (VEGFRi) achieves topical efficacy in rat and monkey models of choroidal neovascularization (CNV)

Stephen H Poor; Yubin Qiu; Amber Woolfenden; Debby Long; Christopher M Adams; Jason Elliott; Vinayak Hosagrahara; Jeremy M Sivak; Bruce D Jaffee

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):3380. doi:

Retina October 2014

Reliability of the Mouse Model of Choroidal Neovascularization Induced by Laser Photocoagulation

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Stephen H. Poor; Yubin Qiu; Elizabeth S. Fassbender; Siyuan Shen; Amber Woolfenden; Andrea Delpero; Yong Kim; Natasha Buchanan; Thomas C. Gebuhr; Shawn M. Hanks; Erik L. Meredith; Bruce D. Jaffee; Thaddeus P. Dryja
TAGS: choroidal neovascularization, lasers, light coagulation, mice, reliability
Invest. Ophthalmol. Vis. Sci.. 2014; 55(10):6525-6534. doi: https://doi.org/10.1167/iovs.14-15067

Includes: Supplemental Content

ARVO Annual Meeting Abstract April 2014

Intravitreal (IVT) injection exacerbates murine choroidal neovascularization (CNV) area by a MYD88 dependent mechanism

Elizabeth Fassbender; Yubin Qiu; Siyuan Shen; Amber Woolfenden; Andrea Delpero; Yong Kim; Bruce D Jaffee; Stephen H Poor

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):1194. doi:

ARVO Annual Meeting Abstract June 2013

EphA2 Stimulation of Angiogenesis is Dependent on VEGFR2

Luciana Ferrara; Andrea De Erkenez; Elizabeth Fassbender; Siyuan Shen; Amber Woolfenden; Yubin Qiu; Stephen Poor; Karen Anderson; Bruce Jaffee

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):5613. doi:

ARVO Annual Meeting Abstract June 2013

Validation and Characterization of Murine Oxygen-induced Retinopathy of Prematurity Model

Yubin Qiu; Amber Woolfenden; Wei Zheng; Karen Anderson; Melinda Hubbard; John Demirs; Joseph Loureiro; Joy Ghosh; Stephen Poor; Bruce Jaffee

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):617. doi:

ARVO Annual Meeting Abstract March 2012

Complement Play A Minor Role In Mouse Laser-induced Choroidal Neovascularization

Stephen H. Poor; Elizabeth Fassbender; Siyuan Shen; Yubin Qiu; Amber Woolfenden; John Demirs; Karen Anderson; Bruce D. Jaffee

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):1642. doi:

ARVO Annual Meeting Abstract March 2012

In Vitro And In Vivo Response Of VEGFR-2 To VEGF165 With/Without Ranibizumab

Amber Woolfenden; Elizabeth Fassbender; Siyuan Shen; Kathyrn McAllister; Lisa Baker; Bruce D. Jaffee; Stephen H. Poor; Yubin Qiu

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):2962. doi:

ARVO Annual Meeting Abstract April 2011

Intravitreal Ranibizumab Inhibits Injected VEGF-induced Pathology In Rabbits Up To 9 Weeks After A Single Injection

Stephen H. Poor; Chad E. Bigelow; Yubin Qiu; Shawn M. Hanks; Elizabeth Fassbender; Siyuan Shen; Amber Woolfenden; Bruce D. Jaffee

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):972. doi:

ARVO Annual Meeting Abstract April 2011

Development of a Rabbit Model to Assess Anti-Angiogenic Therapies that Modulate Human VEGF-Mediated Retinal Vessel Pathology

Chad E. Bigelow; Stephen Poor; Yubin Qiu; Shawn M. Hanks; Michael Maker; Elizabeth Fassbender; Siyuan Shen; Amber Woolfenden; Bruce D. Jaffee

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):1384. doi:

ARVO Annual Meeting Abstract April 2011

Analysis of Laser-induced Choroidal Neovascularization (CNV) Area from 143 Control Cohorts

Siyuan Shen; Yubin Qiu; Elizabeth Fassbender; Amber Woolfenden; Bruce D. Jaffee; Stephen H. Poor

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):3974. doi:

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