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ARVO Annual Meeting Abstract June 2024

In-depth analysis of the molecular mechanisms underlying the differences in vascularization and inflammatory response in two extreme CC strains using total RNAseq

Thomas Clahsen; Christian Buettner; Felix Bock; Niloofar Hatami; Felix Nüst; Tim Gabriel; Lois Balmer; Grant Morahan; Claus Cursiefen; Andre Reis

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2918.

ARVO Annual Meeting Abstract June 2024

Absence of tyrosinase leads to altered distribution of corneal immune cells, corneal thinning and reduced corneal graft survival

Šejla Gegić; takahiko hayashi; Wei Zhang; Felix Bock; Niloofar Hatami; Christian Büttner; Andre Reis; Claus Cursiefen; Thomas Clahsen

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2906.

ARVO Annual Meeting Abstract June 2022

Tyrosinase reduces expression of vascular endothelial growth factors and improves corneal graft survival

Thomas Clahsen; Niloofar Hatami; Christian Büttner; André Reis; Claus Cursiefen

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):909 – A0273.

ARVO Annual Meeting Abstract June 2021

Cystathionine β-synthase as novel regulator of lymphangiogenesis

Niloofar Hatami; Christian Büttner; Felix Bock; Sara Simfors; André Reis; Claus Cursiefen; Thomas Clahsen

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):899.

ARVO Annual Meeting Abstract June 2021

Genetic variability of lymphangiogenesis in Collaborative Cross mice: a powerful tool to identify novel endogenous regulators of lymphangiogenesis

Thomas Clahsen; Christian Büttner; Niloofar Hatami; Felix Nüst; Tim Gabriel; André Reis; Claus Cursiefen

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):896.

ARVO Annual Meeting Abstract June 2020

Analysis of genetically determined gene expression suggest role of inflammatory processes in etiology of exfoliation syndrome

Jibril Hirbo; Francesca Pasutto; Julia Sealock; Patrick Evans; Priyanka Pawar; Ran Tao; Peter Straub; Max Breyer; Daniel Berner; Andre Reis; Ursula Schlötzer-Schrehardt; CC Khor; Eric Gamazon; Milam A Brantley; Karen M Joos; Nancy Cox

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1255.

ARVO Annual Meeting Abstract July 2019

Tyrosinase is a novel endogenous inhibitor of lymphangiogenesis

Thomas Clahsen; Christian Büttner; Birgit Regenfuss; Tim Gabriel; Felix Bock; André Reis; Claus Cursiefen

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):942.

ARVO Annual Meeting Abstract July 2019

Functional implication of the pseudoexfoliation-associated rare variant p.Y407F at LOXL1

Daniel Berner; Ursula Hoja; Matthias Zenkel; Francesca Pasutto; Mei Chin Lee; Tin Aung; Chiea Chuen Khor; André Reis; Friedrich E Kruse; Ursula Schlotzer-Schrehardt

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1612.

ARVO Annual Meeting Abstract July 2019

Identifying Genes that Underlie Exfoliation Syndrome using Genetically Determined Gene Expression

Jibril Hirbo; Francesca Pasutto; Priyanka Pawar; Julia Sealock; Patrick Evans; Eric Gamazon; Ran Tao; André Reis; Daniel Berner; Ursula Schlotzer-Schrehardt; Milam A Brantley; Chiea Chuen Khor; Nancy Cox; Karen M Joos

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):6072.

ARVO Annual Meeting Abstract July 2018

RNA-seq and pathway analysis of ocular tissues in PEX patients and healthy subjects

Francesca Pasutto; Matthias Zenkel; Daniel Berner; Steffen Uebe; Arif Ekici; Friedrich E Kruse; Andre Reis; Ursula Schlotzer-Schrehardt

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3019.

ARVO Annual Meeting Abstract July 2018

Tyrosinase downregulates Fibromodulin-induced lymphangiogenesis

Thomas Clahsen; Birgit Regenfuss; Christian Büttner; Tim Gabriel; Felix Bock; Andre Reis; Claus Cursiefen

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3330.

ARVO Annual Meeting Abstract July 2018

Pseudoexfoliation associated protective variant, rs7173049, reveals a novel regulatory region downstream of LOXL1

Daniel Berner; Francesca Pasutto; Ursula Hoja; Matthias Zenkel; Mineo Ozaki; Susan Williams; Michele Ramsay; Trevor R Carmichael; Friedrich E Kruse; Tin Aung; Chiea Chuen Khor; Andre Reis; Ursula Schlotzer-Schrehardt

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3515.

Glaucoma November 2017

Posttranscriptional Regulation of LOXL1 Expression Via Alternative Splicing and Nonsense-Mediated mRNA Decay as an Adaptive Stress Response

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Daniel Berner; Matthias Zenkel; Francesca Pasutto; Ursula Hoja; Panah Liravi; Gabriele C. Gusek-Schneider; Friedrich E. Kruse; Johannes Schödel; Andre Reis; Ursula Schlötzer-Schrehardt
TAGS: alternative splicing, body tissue, regulation, rna, messenger, stress response, caffeine, syndrome, western blotting, proteins, stress
Invest. Ophthalmol. Vis. Sci.. 2017; 58(13):5930-5940. https://doi.org/10.1167/iovs.17-22963

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2017

Tyrosinase: a novel endogenous regulator of (corneal) lymphangiogenesis

Thomas Clahsen; Birgit Regenfuss; Christian Büttner; Marie-Luise Dreisow; Tim Gabriel; Felix Bock; André Reis; Claus Cursiefen

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1009.

ARVO Annual Meeting Abstract June 2017

L- and M-cone driven temporal contrast sensitivity is reduced at low frequencies in patients with Stargardt’s disease

Cord R H Huchzermeyer; Francesca Pasutto; André Reis; Jan J Kremers

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):4299.

ARVO Annual Meeting Abstract June 2017

Dysregulated expression of POMP and TMEM136 may contribute to impaired proteasome function and endothelial dysfunction in eyes with pseudoexfoliation syndrome/glaucoma

Matthias Zenkel; Ursula Schlotzer-Schrehardt; Daniel Berner; Friedrich E Kruse; André Reis; Chiea Chuen Khor; Tin Aung; Francesca Pasutto

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):4902.

ARVO Annual Meeting Abstract June 2017

Alternative splicing and nonsense-mediated mRNA decay contribute to regulation of LOXL1 expression in response to cellular stress in pseudoexfoliation

Daniel Berner; Matthias Zenkel; Francesca Pasutto; Johannes Schödel; André Reis; Friedrich E Kruse; Ursula Schlotzer-Schrehardt

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):4909.

ARVO Annual Meeting Abstract September 2016

LOXL1 intronic variants influence LOXL1 expression through differential transcription factor binding in pseudoexfoliation syndrome/glaucoma

Ursula Schlötzer-Schrehardt; Matthias Zenkel; Ursula Hoja; Mineo Ozaki; Tin Aung; Chiea-Chuen Khor; Friedrich E Kruse; Andre Reis; Francesca Pasutto

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):789.

ARVO Annual Meeting Abstract June 2015

Strain-dependent changes in the limbal lymphatic vasculature in BALB/c and C57BL/6 mice during aging

Birgit Regenfuss; Marie-Luise Dreisow; Zita Steiber; Christian Buettner; André Reis; Deniz Hos; Claus Cursiefen

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):4501.

ARVO Annual Meeting Abstract March 2012

Novel Stra6 Null Mutations In The Original Patient With Matthew-wood Syndrome

Francesca Pasutto; Frances Flinter; André Reis; Anita Rauch

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):4929.

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In-depth analysis of the molecular mechanisms underlying the differences in vascularization and inflammatory response in two extreme CC strains using total RNAseq

Absence of tyrosinase leads to altered distribution of corneal immune cells, corneal thinning and reduced corneal graft survival

Tyrosinase reduces expression of vascular endothelial growth factors and improves corneal graft survival

Cystathionine β-synthase as novel regulator of lymphangiogenesis

Genetic variability of lymphangiogenesis in Collaborative Cross mice: a powerful tool to identify novel endogenous regulators of lymphangiogenesis

Analysis of genetically determined gene expression suggest role of inflammatory processes in etiology of exfoliation syndrome

Tyrosinase is a novel endogenous inhibitor of lymphangiogenesis

Functional implication of the pseudoexfoliation-associated rare variant p.Y407F at LOXL1

Identifying Genes that Underlie Exfoliation Syndrome using Genetically Determined Gene Expression

RNA-seq and pathway analysis of ocular tissues in PEX patients and healthy subjects

Tyrosinase downregulates Fibromodulin-induced lymphangiogenesis

Pseudoexfoliation associated protective variant, rs7173049, reveals a novel regulatory region downstream of LOXL1

Posttranscriptional Regulation of LOXL1 Expression Via Alternative Splicing and Nonsense-Mediated mRNA Decay as an Adaptive Stress Response

Tyrosinase: a novel endogenous regulator of (corneal) lymphangiogenesis

L- and M-cone driven temporal contrast sensitivity is reduced at low frequencies in patients with Stargardt’s disease

Dysregulated expression of POMP and TMEM136 may contribute to impaired proteasome function and endothelial dysfunction in eyes with pseudoexfoliation syndrome/glaucoma

Alternative splicing and nonsense-mediated mRNA decay contribute to regulation of LOXL1 expression in response to cellular stress in pseudoexfoliation

LOXL1 intronic variants influence LOXL1 expression through differential transcription factor binding in pseudoexfoliation syndrome/glaucoma

Strain-dependent changes in the limbal lymphatic vasculature in BALB/c and C57BL/6 mice during aging

Novel Stra6 Null Mutations In The Original Patient With Matthew-wood Syndrome

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