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Review April 2021

Inflammation in Viral Vector-Mediated Ocular Gene Therapy: A Review and Report From a Workshop Hosted by the Foundation Fighting Blindness, 9/2020

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Ying Kai Chan; Andrew D. Dick; Sara Mary Hall; Thomas Langmann; Curtis L. Scribner; Brian C. Mansfield; for the Ocular Gene Therapy Inflammation Working Group
TAGS: blindness, gene therapy, inflammation, spatial vectors, disease vectors
Trans. Vis. Sci. Tech.. 2021; 10(4):3. doi: https://doi.org/10.1167/tvst.10.4.3

Clinical and Epidemiologic Research May 2020

Ambient Air Pollution Associations with Retinal Morphology in the UK Biobank

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Sharon Y. L. Chua; Anthony P. Khawaja; Andrew D. Dick; James Morgan; Baljean Dhillon; Andrew J. Lotery; Nicholas G. Strouthidis; Charles Reisman; Tunde Peto; Peng T. Khaw; Paul J. Foster; Praveen J. Patel; on behalf of The UK Biobank Eye and Vision Consortium
TAGS: air pollution, biobanks, language morphology, morphology
Invest. Ophthalmol. Vis. Sci.. 2020; 61(5):32. doi: https://doi.org/10.1167/iovs.61.5.32

Glaucoma November 2019

The Relationship Between Ambient Atmospheric Fine Particulate Matter (PM 2.5 ) and Glaucoma in a Large Community Cohort

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Sharon Y. L. Chua; Anthony P. Khawaja; James Morgan; Nicholas Strouthidis; Charles Reisman; Andrew D. Dick; Peng T. Khaw; Praveen J. Patel; Paul J. Foster; for the UK Biobank Eye and Vision Consortium
TAGS: cohort studies, glaucoma, particulate matter, community, intraocular pressure, self-report, air pollution
Invest. Ophthalmol. Vis. Sci.. 2019; 60(14):4915-4923. doi: https://doi.org/10.1167/iovs.19-28346

Articles October 2019

Modelling Macular Edema: The Effect of IL-6 and IL-6R Blockade on Human Blood–Retinal Barrier Integrity In Vitro

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Marina Mesquida; Faye Drawnel; Philippa J. Lait; David A. Copland; Madeleine L. Stimpson; Victor Llorenç; Maite Sainz de la Maza; Alfredo Adan; Gabriella Widmer; Pamela Strassburger; Sascha Fauser; Andrew D. Dick; Richard W. J. Lee; Blanca Molins
TAGS: interleukin 6 receptor, interleukin-6, macular edema, personal integrity, blood-retinal barrier
Trans. Vis. Sci. Tech.. 2019; 8(5):32. doi: https://doi.org/10.1167/tvst.8.5.32

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2019

Upregulation of CX3CR1 on CD4+ T cells during Experimental Autoimmune Uveoretinitis

Amy Ward; Oliver Hugh Bell; Louis Scott; David Copland; Andrew D Dick; Lindsay B Nicholson

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):784. doi:

ARVO Annual Meeting Abstract July 2019

Interleukin-33 attenuates ocular angiogenesis through a mast cell dependent pathway.

Sofia Theodoropoulou; David Copland; Kepeng Ou; Jian Liu; Neal Millar; Andrew D Dick

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):987. doi:

ARVO Annual Meeting Abstract July 2019

RNA-Seq Reveals Alterations in Homeostatic Microglial Function during Inflammation and Resolution

Oliver Hugh Bell; David Copland; Amy Ward; Colin J Chu; Clemens Lange; Andrew D Dick

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2800. doi:

ARVO Annual Meeting Abstract July 2019

Gene therapy for Glaucoma by CRISPR-Cas9 mediated disruption of Aquaporin 1 in the Ciliary Body

Colin J Chu; Jiahui Wu; Oliver Hugh Bell; David Copland; Ryea Maswood; Alison Young; John Pooley; Peng Tee Khaw; Robin R Ali; Andrew D Dick

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5120. doi:

ARVO Annual Meeting Abstract July 2019

Mapping interleukin-33 to metabolic function in the retinal pigment epithelium

Louis Scott; Emma E Vincent; Natalie Hudson; David Copland; Kate Heesom; Matthew Campbell; Andrew Halestrap; Andrew D Dick; Sofia Theodoropoulou

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1685. doi:

Special Issue July 2018

A Perspective of AMD Through the Eyes of Immunology

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David A. Copland; Sofia Theodoropoulou; Jian Liu; Andrew D. Dick
TAGS: body tissue, eye, immunology, inflammation, complement system proteins, microglia
Invest. Ophthalmol. Vis. Sci.. 2018; 59(4):AMD83-AMD92. doi: https://doi.org/10.1167/iovs.18-23893

ARVO Annual Meeting Abstract July 2018

Modulation of mast cells regulates retinal microenvironment and vascular integrity.

Sofia Theodoropoulou; David A Copland; Jian Liu; Louis Scott; Jiahui Wu; Andrew D Dick

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):5555. doi:

ARVO Annual Meeting Abstract July 2018

Clinical spectrum of vitreoretinal lymphoma and its association with MyD88 L265P mutation

Ester Carreno; Timothy Clench; Laura R Steeples; Serena Salvatore; Richard W. J. Lee; Andrew D Dick; Joya Pawade

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):5578. doi:

Articles October 2017

Augmenting Endogenous Levels of Retinal Annexin A1 Suppresses Uveitis in Mice

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Peter J. Gardner; Samia Yazid; Joana Ribeiro; Robin R. Ali; Andrew D. Dick
TAGS: annexin a1, mice, uveitis, retina, eye
Trans. Vis. Sci. Tech.. 2017; 6(5):10. doi: https://doi.org/10.1167/tvst.6.5.10

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2017

In vitro effects of IL-6 and IL-6R blockade on the blood-retinal barrier

Marina Mesquida; David A Copland; Philippa J P Lait; Victor Llorens; Maite Sainz De La Maza; Alfredo Adan Civera; Andrew D Dick; Richard W J Lee; Blanca Molins

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):5728. doi:

ARVO Annual Meeting Abstract June 2017

A prospective, longitudinal observational study of patients receiving TNFα inhibitors for refractory ocular inflammation.

Colm David Andrews; Erika Damato; Annie Hinchcliffe; Kate Tilling; Andrew D Dick; Srilakshmi M Sharma

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1230. doi:

ARVO Annual Meeting Abstract June 2017

Interleukin 33 attenuates choroidal neovascularization by activating mast cells.

Sofia Theodoropoulou; David A Copland; Jian Liu; Jiahui Wu; Andrew D Dick

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1627. doi:

ARVO Annual Meeting Abstract June 2017

New staging of Acute Posterior Multifocal Placoid Pigment Epiteliopathy by using multimodal imaging

Ester Carreno; Tomas Burke; Colin Chu; Serena Salvatore; Richard W J Lee; Clare Bailey; Andrew D Dick; Adam H Ross

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):5995. doi:

ARVO Annual Meeting Abstract June 2017

Immunohistochemical examination of the B lymphocyte infiltrate in human uveitis

Simon Epps; Natalie Coplin; Philip J Luthert; Andrew D Dick; Sarah E. Coupland; Lindsay B Nicholson

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):553. doi:

ARVO Annual Meeting Abstract June 2017

The suppressive effect of the epigenetic drug, Givinostat (ITF2357), on peripheral blood leukocytes from uveitis patients

Lauren P Schewitz-Bowers; Philippa J P Lait; Wei Chen; Ester Carreno; Xiao Hu; Zhiyu Li; Jing Chen; Kara M Ponsford; Andrew D Dick; Lai Wei; Rachel R Caspi; Richard W J Lee; Benjamin Chaigne-Delalande

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):510. doi:

ARVO Annual Meeting Abstract June 2017

Quantification of flow at baseline and follow-up in uveitic and non-age-related macular degeneration choroidal neovascular membranes (CNVM) using Optical Coherence Tomography-Angiography (OCT-A).

Tomas Burke; Ester Carreno; Clare Bailey; Richard W J Lee; Andrew D Dick; Adam H Ross

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1643. doi:

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Inflammation in Viral Vector-Mediated Ocular Gene Therapy: A Review and Report From a Workshop Hosted by the Foundation Fighting Blindness, 9/2020

Ambient Air Pollution Associations with Retinal Morphology in the UK Biobank

The Relationship Between Ambient Atmospheric Fine Particulate Matter (PM 2.5 ) and Glaucoma in a Large Community Cohort

Modelling Macular Edema: The Effect of IL-6 and IL-6R Blockade on Human Blood–Retinal Barrier Integrity In Vitro

Upregulation of CX3CR1 on CD4+ T cells during Experimental Autoimmune Uveoretinitis

Interleukin-33 attenuates ocular angiogenesis through a mast cell dependent pathway.

RNA-Seq Reveals Alterations in Homeostatic Microglial Function during Inflammation and Resolution

Gene therapy for Glaucoma by CRISPR-Cas9 mediated disruption of Aquaporin 1 in the Ciliary Body

Mapping interleukin-33 to metabolic function in the retinal pigment epithelium

A Perspective of AMD Through the Eyes of Immunology

Modulation of mast cells regulates retinal microenvironment and vascular integrity.

Clinical spectrum of vitreoretinal lymphoma and its association with MyD88 L265P mutation

Augmenting Endogenous Levels of Retinal Annexin A1 Suppresses Uveitis in Mice

In vitro effects of IL-6 and IL-6R blockade on the blood-retinal barrier

A prospective, longitudinal observational study of patients receiving TNFα inhibitors for refractory ocular inflammation.

Interleukin 33 attenuates choroidal neovascularization by activating mast cells.

New staging of Acute Posterior Multifocal Placoid Pigment Epiteliopathy by using multimodal imaging

Immunohistochemical examination of the B lymphocyte infiltrate in human uveitis

The suppressive effect of the epigenetic drug, Givinostat (ITF2357), on peripheral blood leukocytes from uveitis patients

Quantification of flow at baseline and follow-up in uveitic and non-age-related macular degeneration choroidal neovascular membranes (CNVM) using Optical Coherence Tomography-Angiography (OCT-A).

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