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ARVO Annual Meeting Abstract June 2024

Altered retinal capillary reactivity correlates with impaired microglial calcium-dependent vasoregulation in the STZ model of diabetes

Andrew Ian Jobling; Pialuisa Quiriconi; Una Greferath; Bang V Bui; Michael Alexander Dixon; Erica L Fletcher

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):867.

ARVO Annual Meeting Abstract June 2024

Targeting VEGFB signaling to reduce early changes in the retina during diabetes

Erica L Fletcher; Kiana Kakavand; Gene Venables; Magda Montgomery; Elena Velkoska; Pierre Scotney; Una Greferath; Andrew Ian Jobling

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):336.

ARVO Annual Meeting Abstract June 2024

Increased RNA editing of inflammatory and vision-related genes in the RPE with age

Josephine Hiao Ching Wong; Brendan Robert E Ansell; Alice Brandli; Andrew Ian Jobling; Erica L Fletcher

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2180.

ARVO Annual Meeting Abstract June 2023

Microglia regulate blood vessel tone and blood flow in the retina via Cx3cr1, purinergic, and glutamatergic mechanisms

Michael Alexander Dixon; Samuel Alexander Mills; Bang Bui; Vickie Wong; Da Zhao; Andrew Ian Jobling; Erica L Fletcher

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):2943.

ARVO Annual Meeting Abstract June 2023

Retinal microglia regulate blood vessel calibre in the superficial but not deep vascular plexus

Pialuisa Quiriconi; Michael Alexander Dixon; Una Greferath; Andrew Ian Jobling; Erica Lucy Fletcher

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):1993.

ARVO Annual Meeting Abstract June 2023

Blockade of the toll like receptor co-factor, CD14, reduces angiogenesis and fibrosis in models of neovascular age related macular degeneration.

Erica L Fletcher; Gene Venables; Brian Ziegelaar; Garry Redlich; Xilun Wang; Una Greferath; George Magrath; Andrew Ian Jobling

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):2944.

ARVO Annual Meeting Abstract June 2023

Leukocyte mediated mechanisms of subretinal fibrosis in neovascular age-related macular degeneration

Josephine Hiao Ching Wong; Alice Brandli; Matt Rutar; Ellie Cho; Andrew Ian Jobling; Erica L Fletcher

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):2722.

Glaucoma September 2019

Reversibility of Retinal Ganglion Cell Dysfunction From Chronic IOP Elevation

PDF

Da Zhao; Vickie H. Y. Wong; Christine T. O. Nguyen; Andrew I. Jobling; Erica L. Fletcher; Algis J. Vingrys; Bang V. Bui
TAGS: ganglia, intraocular pressure, pathophysiology, recovery of function, retinal ganglion cells, electroretinography, eye, sutures, mice
Invest. Ophthalmol. Vis. Sci.. 2019; 60(12):3878-3886. https://doi.org/10.1167/iovs.19-27113

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2019

Functional microglial involvement in the neurovascular unit

Michael Alexander Dixon; Andrew Ian Jobling; Joanna Phipps; Samuel Alexander Mills; Erica L Fletcher

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1640.

ARVO Annual Meeting Abstract July 2019

The local and systemic effects following subthreshold nanosecond laser treatment to the posterior retina

Quan Findlay; Andrew Ian Jobling; Kirstan Anne Vessey; Ursula Greferath; Pavan Avula; Ben Gu; Robyn H Guymer; Erica L Fletcher

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):364.

Retinal Cell Biology October 2018

Failure of Autophagy–Lysosomal Pathways in Rod Photoreceptors Causes the Early Retinal Degeneration Phenotype Observed in Cln6 nclf Mice

PDF

Philipp von Eisenhart-Rothe; Alexandra Grubman; Ursula Greferath; Linda J. Fothergill; Andrew I. Jobling; Joanna A. Phipps; Anthony R. White; Erica L. Fletcher; Kirstan A. Vessey
TAGS: autophagy, mice, photoreceptors, rod photoreceptors, retinal degeneration, retina
Invest. Ophthalmol. Vis. Sci.. 2018; 59(12):5082-5097. https://doi.org/10.1167/iovs.18-24757

ARVO Annual Meeting Abstract July 2018

Reversibility of retinal ganglion cell dysfunction due to chronic IOP elevation.

Da Zhao; Vickie Hoi Ying Wong; Zheng He; Christine Tram Oanh Nguyen; Andrew Ian Jobling; Erica Fletcher; Holly Chinnery; Patricia Jusuf; Jeremiah K.H. Lim; Algis J Vingrys; Bang V Bui

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3696.

ARVO Annual Meeting Abstract July 2018

Microglial involvement in the neurovascular unit and alterations during early diabetic retinopathy

Andrew Ian Jobling; Samuel A Mills; Joanna Amy Phipps; Kirstan Anne Vessey; Michael A Dixon; Una Greferath; Bang V Bui; Erica L Fletcher

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):5379.

ARVO Annual Meeting Abstract July 2018

Treatment of age related macular degeneration using nanosecond laser therapy: Safety profile studies in humans and mice

Kirstan Anne Vessey; Tracy Ho; Andrew Ian Jobling; Samuel A Mills; Mai Tran; Alice Brandli; Jackson Lam; Robyn H Guymer; Erica L Fletcher

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):6080.

Retinal Cell Biology February 2018

Nanosecond Laser Treatment for Age-Related Macular Degeneration Does Not Induce Focal Vision Loss or New Vessel Growth in the Retina

PDF

Kirstan A. Vessey; Tracy Ho; Andrew I. Jobling; Samuel A. Mills; Mai X. Tran; Alice Brandli; Jackson Lam; Robyn H. Guymer; Erica L. Fletcher
TAGS: laser therapy, lasers, retina, mice, age-related macular degeneration, blindness
Invest. Ophthalmol. Vis. Sci.. 2018; 59(2):731-745. https://doi.org/10.1167/iovs.17-23098

Retinal Cell Biology January 2018

The Role of Angiotensin II/AT1 Receptor Signaling in Regulating Retinal Microglial Activation

PDF

Joanna A. Phipps; Kirstan A. Vessey; Alice Brandli; Nupur Nag; Mai X. Tran; Andrew I. Jobling; Erica L. Fletcher
TAGS: angiotensin ii, microglia, signal transduction, retina, intravitreal injections, eye
Invest. Ophthalmol. Vis. Sci.. 2018; 59(1):487-498. https://doi.org/10.1167/iovs.17-22416

Includes: Multimedia, Supplemental Content

ARVO Annual Meeting Abstract June 2017

The role of pro-apoptotic proteins Bak and Bax in rd1 rodent model of retinitis pigmentosa

Kiana Kakavand; Andrew Ian Jobling; Robbert De Iongh; Stephane Chappaz; Benjamin T. Kyle; Erica L Fletcher

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):5373.

Biochemistry and Molecular Biology April 2017

Reduced Scleral TIMP-2 Expression Is Associated With Myopia Development: TIMP-2 Supplementation Stabilizes Scleral Biomarkers of Myopia and Limits Myopia Development

PDF

Hsin-Hua Liu; Megan S. Kenning; Andrew I. Jobling; Neville A. McBrien; Alex Gentle
TAGS: gelatinase a, myopia, sclera, timp2 protein, human, collagen
Invest. Ophthalmol. Vis. Sci.. 2017; 58(4):1971-1981. https://doi.org/10.1167/iovs.16-21181

ARVO Annual Meeting Abstract September 2016

Microglial dynamics and phenotype are altered by Angiotensin II in the mouse retina

Joanna Phipps; Kirstan Vessey; Nupur Nag; Andrew Ian Jobling; Erica L Fletcher

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):2232.

ARVO Annual Meeting Abstract September 2016

A novel model of type 1 diabetes shows neuronal, glial and vascular pathology.

Erica L Fletcher; Michael Dixon; Samuel Alexander Mills; Joanna Phipps; Kirstan Vessey; Dirk Wedekind; Andrew Ian Jobling

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):2714.

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Altered retinal capillary reactivity correlates with impaired microglial calcium-dependent vasoregulation in the STZ model of diabetes

Targeting VEGFB signaling to reduce early changes in the retina during diabetes

Increased RNA editing of inflammatory and vision-related genes in the RPE with age

Microglia regulate blood vessel tone and blood flow in the retina via Cx3cr1, purinergic, and glutamatergic mechanisms

Retinal microglia regulate blood vessel calibre in the superficial but not deep vascular plexus

Blockade of the toll like receptor co-factor, CD14, reduces angiogenesis and fibrosis in models of neovascular age related macular degeneration.

Leukocyte mediated mechanisms of subretinal fibrosis in neovascular age-related macular degeneration

Reversibility of Retinal Ganglion Cell Dysfunction From Chronic IOP Elevation

Functional microglial involvement in the neurovascular unit

The local and systemic effects following subthreshold nanosecond laser treatment to the posterior retina

Failure of Autophagy–Lysosomal Pathways in Rod Photoreceptors Causes the Early Retinal Degeneration Phenotype Observed in Cln6 nclf Mice

Reversibility of retinal ganglion cell dysfunction due to chronic IOP elevation.

Microglial involvement in the neurovascular unit and alterations during early diabetic retinopathy

Treatment of age related macular degeneration using nanosecond laser therapy: Safety profile studies in humans and mice

Nanosecond Laser Treatment for Age-Related Macular Degeneration Does Not Induce Focal Vision Loss or New Vessel Growth in the Retina

The Role of Angiotensin II/AT1 Receptor Signaling in Regulating Retinal Microglial Activation

The role of pro-apoptotic proteins Bak and Bax in rd1 rodent model of retinitis pigmentosa

Reduced Scleral TIMP-2 Expression Is Associated With Myopia Development: TIMP-2 Supplementation Stabilizes Scleral Biomarkers of Myopia and Limits Myopia Development

Microglial dynamics and phenotype are altered by Angiotensin II in the mouse retina

A novel model of type 1 diabetes shows neuronal, glial and vascular pathology.

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