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Telemedicine March 2024

Inequalities in Uptake and Use of Digital Applications for Home-Monitoring of Neovascular Age-Related Macular Degeneration in an Elderly Visually Impaired Population: The MONARCH Study

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Ruth E. Hogg; Robin Wickens; Sean O'Connor; Eleanor Gidman; Elizabeth Ward; Tunde Peto; Benjamen J. L. Burton; Paul Knox; Andrew J. Lotery; Sobha Sivaprasad; Michael Donnelly; Chris A. Rogers; Barnaby C. Reeves
TAGS: exudative age-related macular degeneration, older adult, technology, follow-up
Trans. Vis. Sci. Tech.. 2024; 13(3):2. https://doi.org/10.1167/tvst.13.3.2

Retina August 2023

Comparison of Novel Volumetric Microperimetry Metrics in Intermediate Age-Related Macular Degeneration: PINNACLE Study Report 3

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Philipp Anders; Ghislaine L. Traber; Maximilian Pfau; Sophie Riedl; Ahmed M. Hagag; Hanna Camenzind; Julia Mai; Rebecca Kaye; Hrvoje Bogunović; Lars G. Fritsche; Daniel Rueckert; Ursula Schmidt-Erfurth; Sobha Sivaprasad; Andrew J. Lotery; Hendrik P. N. Scholl
TAGS: age-related macular degeneration, study report, visual acuity, software
Trans. Vis. Sci. Tech.. 2023; 12(8):21. https://doi.org/10.1167/tvst.12.8.21

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2023

MacuSIM: An in-vitro model of the outer retina as an experimental platform for macular disease and therapeutic trials

J. Arjuna Ratnayaka; David A Johnston; Ben Mills; Andrew J Lotery; Tracey A Newman; Savannah Amy Lynn

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):4743.

ARVO Annual Meeting Abstract June 2023

Deep-learning-based clustering of OCT images for automated biomarker discovery in age-related macular degeneration

Robbie Holland; Oliver Leingang; Ahmed M Hagag; Christopher Holmes; Philipp Anders; Johannes C. C. Paetzold; Rebecca Kaye; Sophie Riedl; Hrvoje Bogunovic; Ursula Schmidt-Erfurth; Hendrik P Scholl; Daniel Rueckert; Andrew J Lotery; Sobha Sivaprasad; Martin Joseph Menten

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):1283.

ARVO Annual Meeting Abstract June 2023

IMPG2 -related maculopathy

Johannes Birtel; Richard Caswell; Samantha R De Silva; Philipp Herrmann; Salwah Rehman; Andrew J Lotery; Omar Abdul Rahman Mahroo; Michel Michaelides; Andrew R Webster; Robert E MacLaren; Peter Charbel Issa

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):4643.

ARVO Annual Meeting Abstract June 2023

Regional Variation of Retinal Sensitivity in Intermediate AMD in the PINNACLE study

Philipp Anders; Ghislaine L Traber; Maximilian Pfau; Sophie Riedl; Julia Mai; Hanna Camenzind; Chrysoula Gabrani; Rebecca Kaye; Toby Prevost; Hrvoje Bogunovic; Lars G Fritsche; Daniel Rueckert; Ursula Schmidt-Erfurth; Sobha Sivaprasad; Andrew J Lotery; Hendrik P Scholl

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):4328.

ARVO Annual Meeting Abstract June 2023

Intraluminal acidity plays a key role in the function of lysosomes in RPE cells

Rebecca Denise Miller; Savannah Amy Lynn; Eloise Keeling; Charles Ellis; David Chatelet; David A Johnston; David A Tumbarello; Andrew J Lotery; Arjuna Ratnayaka

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):3891.

ARVO Annual Meeting Abstract June 2023

Self-supervised machine learning for individual prediction of conversion to neovascular AMD in PINNACLE study

Arunava Chakravarty; Taha Emre; Oliver Leingang; Sophie Riedl; Julia Mai; Hendrik P Scholl; Sobha Sivaprasad; Lars G Fritsche; Daniel Rueckert; Andrew J Lotery; Ursula Schmidt-Erfurth; Hrvoje Bogunovic

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):545.

ARVO Annual Meeting Abstract June 2023

Deep learning-based detection of advanced AMD on retinal OCT from the UK Biobank dataset on behalf of the PINNACLE Consortium

Oliver Leingang; Hrvoje Bogunovic; Gregor Sebastian Reiter; Arunava Chakravarty; Martin Joseph Menten; Robert Holland; Lars G Fritsche; Hendrik P Scholl; Daniel Rueckert; Sobha Sivaprasad; Andrew J Lotery; Ursula Schmidt-Erfurth

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):544.

ARVO Annual Meeting Abstract June 2023

Geometric deep learning for disease classification in OCTA images

Johannes C. C. Paetzold; Laurin Lux; Linus Kreitner; Ivan Ezhov; Suprosanna Shit; Andrew J Lotery; Martin Joseph Menten; Daniel Rueckert

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):1098.

ARVO Annual Meeting Abstract June 2023

Deciphering hypereflective foci in age related macular degeneration using adaptive optics in the PINNACLE Study

Christopher Holmes; Syed Ahmer Raza; Ahmed M Hagag; Thomas Taylor; Sophie Riedl; Julia Mai; Toby Prevost; Daniel Rueckert; Hrvoje Bogunovic; Hendrik P Scholl; Ursula Schmidt-Erfurth; Lars G Fritsche; Andrew J Lotery; Sobha Sivaprasad

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):2171.

ARVO Annual Meeting Abstract June 2023

6-year outcomes of the United Kingdom Medisoft® audit study following treatment with the ILUVIEN® (fluocinolone acetonide) implant in patients with diabetic macular edema.

Bushra Mushtaq; Clare C Bailey; Usha Chakravarthy; Andrew J Lotery; James Talks; Geeta Menon

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):2651.

ARVO Annual Meeting Abstract June 2023

CRISPR/Cas9 mutagenesis of Tetraspanin-10, a novel AMD risk variant, impacts human retinal pigment epithelial cell pigmentation and oxidative stress

Rebecca Kaye; Jorn Lakowski; Andrew J Lotery

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):3197.

ARVO Annual Meeting Abstract June 2023

Characterising central serous chorioretinopathy and choroidal thickness in UK Biobank

Catherine Jamison; Barbra Hamill; Michael J Quinn; Alyson Muldrew; Alan Sproule; Peter Blows; Savita Madhusudhan; Konstantinos Balaskas; Andrew J Lotery; Tunde Peto; Paul Foster

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):4184.

Retina February 2023

Repeatability of Quantitative Autofluorescence Imaging in a Multicenter Study Involving Patients With Recessive Stargardt Disease 1

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Patty P.A. Dhooge; Philipp T. Möller; Nils Meland; Katarina Stingl; Camiel J. F. Boon; Andrew J. Lotery; Maurizio Battaglia Parodi; Philipp Herrmann; Wolfgang Klein; Mario G. Fsadni; Thomas H. Wheeler-Schilling; Frank G. Holz; Carel B. Hoyng; Steffen Schmitz-Valckenberg; for the Soraprazan Consortium
TAGS: autofluorescence, diagnostic imaging, multicenter studies, stargardt's disease, reading (activity), eye
Trans. Vis. Sci. Tech.. 2023; 12(2):1. https://doi.org/10.1167/tvst.12.2.1

Includes: Supplemental Content

Genetics November 2022

Zfp503/Nlz2 Is Required for RPE Differentiation and Optic Fissure Closure

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Elangovan Boobalan; Amy H. Thompson; Ramakrishna P. Alur; David M. McGaughey; Lijin Dong; Grace Shih; Emile R. Vieta-Ferrer; Ighovie F. Onojafe; Vijay K. Kalaskar; Gavin Arno; Andrew J. Lotery; Bin Guan; Chelsea Bender; Omar Memon; Lauren Brinster; Clement Soleilhavoup; Lia Panman; Tudor C. Badea; Andrea Minella; Antonio Jacobo Lopez; Sara M. Thomasy; Ala Moshiri; Delphine Blain; Robert B. Hufnagel; Tiziana Cogliati; Kapil Bharti; Brian P. Brooks
TAGS: embryo, fissure, mice, optics, eye, transcription factor
Invest. Ophthalmol. Vis. Sci.. 2022; 63(12):5. https://doi.org/10.1167/iovs.63.12.5

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2022

UK Biobank retinal imaging grading: methods, baseline characteristics and findings for common ocular diseases.

Katie Curran; Alasdair Warwick; Barbra Hamill; Anthony Khawaja; Paul Foster; Andrew J Lotery; Konstantinos Balaskas; Savita Madhusudhan; Michael Joseph Quinn; Alyson Muldrew; catherine Jamison; Peter Blows; David Parry; Nisha Shah; Irene Leung; Tunde Peto

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):993 – F0240.

ARVO Annual Meeting Abstract June 2022

Characterising individuals with retinopathy from retinal image grading data in UK Biobank

Alasdair Warwick; Barbra Hamill; Katie Curran; Anthony Khawaja; Andrew J Lotery; Paul Foster; Konstantinos Balaskas; Michael Joseph Quinn; Savita Madhusudhan; Alan Sproule; Sophie Leach; Daniela Florea; Muldrew Alyson; Laura Cushley; Graham Young; Tunde Peto

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):814.

ARVO Annual Meeting Abstract June 2022

Impact of COVID-19 pandemic on patients with nAMD: Assessing clinical outcomes of patients who underwent four and eight weekly anti-VEGF treatment with no clinic review

Abeir Baltmr; Mohamed Farag; Panos Vouzounis; Sameh Alkhalili; Eslam Ahmed; Mohamed Eldakkak; Samir Khandhadia; Ramez Borbara; Christina Rennie; Gabriella DeSalvo; Andrew J Lotery

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):1340 – F0174.

ARVO Annual Meeting Abstract June 2022

The impact of COVID-19 on visual acuity for nAMD patients treated with aflibercept in the UK

Clare Bailey; Marta Helena Gruszka-Goh; Andrew J Lotery; Romi Chhabra; Haralabos Eleftheriadis; Faruque Ghanchi; Colin Jones; Peter H Scanlon

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):1336 – F0170.

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Inequalities in Uptake and Use of Digital Applications for Home-Monitoring of Neovascular Age-Related Macular Degeneration in an Elderly Visually Impaired Population: The MONARCH Study

Comparison of Novel Volumetric Microperimetry Metrics in Intermediate Age-Related Macular Degeneration: PINNACLE Study Report 3

MacuSIM: An in-vitro model of the outer retina as an experimental platform for macular disease and therapeutic trials

Deep-learning-based clustering of OCT images for automated biomarker discovery in age-related macular degeneration

IMPG2 -related maculopathy

Regional Variation of Retinal Sensitivity in Intermediate AMD in the PINNACLE study

Intraluminal acidity plays a key role in the function of lysosomes in RPE cells

Self-supervised machine learning for individual prediction of conversion to neovascular AMD in PINNACLE study

Deep learning-based detection of advanced AMD on retinal OCT from the UK Biobank dataset on behalf of the PINNACLE Consortium

Geometric deep learning for disease classification in OCTA images

Deciphering hypereflective foci in age related macular degeneration using adaptive optics in the PINNACLE Study

6-year outcomes of the United Kingdom Medisoft® audit study following treatment with the ILUVIEN® (fluocinolone acetonide) implant in patients with diabetic macular edema.

CRISPR/Cas9 mutagenesis of Tetraspanin-10, a novel AMD risk variant, impacts human retinal pigment epithelial cell pigmentation and oxidative stress

Characterising central serous chorioretinopathy and choroidal thickness in UK Biobank

Repeatability of Quantitative Autofluorescence Imaging in a Multicenter Study Involving Patients With Recessive Stargardt Disease 1

Zfp503/Nlz2 Is Required for RPE Differentiation and Optic Fissure Closure

UK Biobank retinal imaging grading: methods, baseline characteristics and findings for common ocular diseases.

Characterising individuals with retinopathy from retinal image grading data in UK Biobank

Impact of COVID-19 pandemic on patients with nAMD: Assessing clinical outcomes of patients who underwent four and eight weekly anti-VEGF treatment with no clinic review

The impact of COVID-19 on visual acuity for nAMD patients treated with aflibercept in the UK

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