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ARVO Annual Meeting Abstract June 2025

Investigating the role of GNGT2-mediated GPCR signalling in cone development

Catherine Robertson; Delphine Boche; Andrew J Lotery; Jörn Lakowski

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):5317.

ARVO Annual Meeting Abstract June 2025

Specializing vision-language models for the clinical management of age-related macular degeneration

Martin Menten; Robbie Holland; Tom Taylor; Christopher Holmes; Sophie Riedl; Julia Mai; Maria Patsiamanidi; Dimitra Mitsopoulou; Paul Hager; Philip Müller; Johannes Paetzold; Hendrik P Scholl; Hrvoje Bogunovic; Ursula Schmidt-Erfurth; Daniel Rückert; Sobha Sivaprasad; Andrew J Lotery

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):863.

ARVO Annual Meeting Abstract June 2025

Early life pre-disposition to diet-induced retinal pathology

Anna-Marie Muir; Savannah A Lynn; Eloise Keeling; Helen Griffiths; Sandrine Willaime-Morawek; Neil R Smyth; Helena Lee; Andrew J Lotery; J. Arjuna Ratnayaka

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):4823.

ARVO Annual Meeting Abstract June 2025

Functional outcomes across high-risk OCT-based phenotypes in intermediate age-related macular degeneration in the prospective PINNACLE study

Marie Louise Enzendorfer; Julia Mai; Sophie Riedl; Hrvoje Bogunovic; Martin Menten; Daniel Rueckert; Lars G Fritsche; A Toby Prevost; Sobha Sivaprasad; Maximilian Pfau; Hendrik P Scholl; Andrew J Lotery; Ursula Schmidt-Erfurth

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):1334.

ARVO Annual Meeting Abstract June 2025

Prototypical Machine Learning for Individual Prediction of Conversion to Atrophic AMD in the PINNACLE Study

Arunava Chakravarty; Julia Mai; Taha Emre; Marie Louise Enzendorfer; Sophie Riedl; Hendrik P Scholl; Sobha Sivaprasad; Lars G Fritsche; Toby Prevost; Martin Menten; Daniel Rueckert; Andrew J Lotery; Hrvoje Bogunovic; Ursula Schmidt-Erfurth

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):4086.

ARVO Annual Meeting Abstract June 2025

Pointwise structure-function correlation between focal event-targeted microperimetry and the first sign of conversion to advanced AMD in the PINNACLE study

Sophie Frank; Klaudia Birner; Julia Mai; Sophie Riedl; Magdalena Baratsits; Simon Schürer-Waldheim; Markus Gumpinger; Hrvoje Bogunovic; Manjula Nugawela; Martin Menten; Daniel Rueckert; Lars G Fritsche; Toby Prevost; Sobha Sivaprasad; Maximilian Pfau; Hendrik P Scholl; Andrew J Lotery; Ursula Schmidt-Erfurth

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):1340.

ARVO Annual Meeting Abstract June 2025

Studies in the 5xFAD mouse retina reveal chronic Amyloid-beta mediated effects, providing new insights into complex retinopathies

J. Arjuna Ratnayaka; Savannah A Lynn; Sudha Priya Soundara Pandi; Aida Sanchez-Bretano; Anna-Marie Muir; Lidia Parker; David S Chatelet; Tutte Newall; Jenny A Scott; Eloise Keeling; Neil R Smyth; James E Self; Helena Lee; Andrew J Lotery

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):1180.

ARVO Annual Meeting Abstract June 2025

Pointwise correlation of deep learning-based quantified features of intermediate AMD on OCT and standardized retinal sensitivity in the prospective PINNACLE study

Julia Mai; Sophie Riedl; Louise Enzendorfer; Hrvoje Bogunovic; Martin Menten; Daniel Rueckert; Lars G Fritsche; A Toby Prevost; Sobha Sivaprasad; Maximilian Pfau; Hendrik P Scholl; Andrew J Lotery; Ursula Schmidt-Erfurth

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):1075.

Retina February 2025

Targeted Microperimetry Grids for Focal Lesions in Intermediate AMD: PINNACLE Study Report 7

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Stefan Futterknecht; Philipp Anders; Julia Mai; Sophie Riedl; Ursula Hall; Chrysoula Gabrani; Kristina Pfau; Martin J. Menten; Daniel Rueckert; A. Toby Prevost; Hrvoje Bogunovic; Lars G. Fritsche; Ursula Schmidt-Erfurth; Sobha Sivaprasad; Andrew Lotery; Hendrik P. N. Scholl; Maximilian Pfau
TAGS: drusen, study report, vision, eye, diagnostic imaging
Invest. Ophthalmol. Vis. Sci.. 2025; 66(2):6. https://doi.org/10.1167/iovs.66.2.6

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2024

Using adaptive optics to assess hyporeflective clumps as a biomarker for progression to cRORA in the PINNACLE study

Christopher Holmes; Naomi Wijesingha; Syed Ahmer Raza; Tom Taylor; Ahmed Hagag; Sophie Riedl; Julia Mai; Daniel Rueckert; Hrvoje Bogunovic; Hendrik P Scholl; Ursula Schmidt-Erfurth; Lars Fritsche; Andrew Lotery; Sobha Sivaprasad

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):3264.

ARVO Annual Meeting Abstract June 2024

A clinical study evaluating biomarkers of immunosenescence in the progression of Age-Related Macular Degeneration (The Immuno AMD Study)

Adnan Khan; Andrew Shapanis; Paul Skipp; Andrew Lotery

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):940.

ARVO Annual Meeting Abstract June 2024

OCT-based AI-assisted phenotyping of intermediate AMD in the prospective PINNACLE trial

Sophie Riedl; Julia Mai; Simon Schürer-Waldheim; Georg Faustmann; Hrvoje Bogunovic; Lars Fritsche; Toby Prevost; Daniel Rueckert; Hendrik P Scholl; Sobha Sivaprasad; Andrew Lotery; Ursula Schmidt-Erfurth

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):980.

ARVO Annual Meeting Abstract June 2024

Molecular and Cellular Mechanisms of Levodopa-Mediated Visual Function Rescue in Albinism

Sarah Macdonald; Eloise Keeling; Jennifer A Scott; Helen Griffiths; Andrew Lotery; J. Arjuna Ratnayaka; James Edward Self; Helena Lee

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):821.

ARVO Annual Meeting Abstract June 2024

Remofuscin slows retinal thinning in Stargardt Disease (STGD1) – results from the Stargardt Remofuscin Treatment Trial (STARTT) a 2-year placebo-controlled study.

Tobias Peters; Katarina Stingl; Wolfgang Klein; Mario G Fsadni; Nils Meland; Patty P.A. Dhooge; Camiel Boon; Andrew Lotery; Maurizio Battaglia Parodi; Philipp Herrmann; Frank G Holz; Steffen Schmitz-Valckenberg; Philipp Möller; Carel C B Hoyng

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2205.

ARVO Annual Meeting Abstract June 2024

Real world treatment intervals in eyes with nAMD treated with Aflibercept. Retrospective UK multicentre study.

Peter Henry Scanlon; Marta Gruszka-Goh; Sharam Kashani; Martin McKibbin; Andrew Lotery; Romi Chhabra; James Talks; Quresh Mohamed

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2117.

ARVO Annual Meeting Abstract June 2024

Evaluating the distribution of fundus autofluorescence phenotypes in a large, European intermediate AMD cohort and describing a novel phenotype (A PINNACLE Study Report)

Tom Taylor; Rebecca Anne Kaye; Julia Mai; Lars Fritsche; Toby Prevost; Daniel Rueckert; Hrvoje Bogunovic; Hendrik P Scholl; Ursula Schmidt-Erfurth; Sobha Sivaprasad; Andrew Lotery

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2266.

ARVO Annual Meeting Abstract June 2024

Patient-tailored Microperimetry Grids for Focal Lesions in Intermediate AMD: A PINNACLE Study Report

Stefan Futterknecht; Maximilian Pfau; Philipp Anders; Julia Mai; Ursula Hall; Hrvoje Bogunovic; Lars Fritsche; Daniel Rueckert; Ursula Schmidt-Erfurth; Sobha Sivaprasad; Andrew Lotery; Hendrik P Scholl

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4386.

Telemedicine March 2024

Inequalities in Uptake and Use of Digital Applications for Home-Monitoring of Neovascular Age-Related Macular Degeneration in an Elderly Visually Impaired Population: The MONARCH Study

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Ruth E. Hogg; Robin Wickens; Sean O'Connor; Eleanor Gidman; Elizabeth Ward; Tunde Peto; Benjamen J. L. Burton; Paul Knox; Andrew J. Lotery; Sobha Sivaprasad; Michael Donnelly; Chris A. Rogers; Barnaby C. Reeves
TAGS: exudative age-related macular degeneration, older adult, technology, follow-up
Trans. Vis. Sci. Tech.. 2024; 13(3):2. https://doi.org/10.1167/tvst.13.3.2

Retina August 2023

Comparison of Novel Volumetric Microperimetry Metrics in Intermediate Age-Related Macular Degeneration: PINNACLE Study Report 3

PDF

Philipp Anders; Ghislaine L. Traber; Maximilian Pfau; Sophie Riedl; Ahmed M. Hagag; Hanna Camenzind; Julia Mai; Rebecca Kaye; Hrvoje Bogunović; Lars G. Fritsche; Daniel Rueckert; Ursula Schmidt-Erfurth; Sobha Sivaprasad; Andrew J. Lotery; Hendrik P. N. Scholl
TAGS: age-related macular degeneration, study report, visual acuity, software
Trans. Vis. Sci. Tech.. 2023; 12(8):21. https://doi.org/10.1167/tvst.12.8.21

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2023

Deep-learning-based clustering of OCT images for automated biomarker discovery in age-related macular degeneration

Robbie Holland; Oliver Leingang; Ahmed M Hagag; Christopher Holmes; Philipp Anders; Johannes C. C. Paetzold; Rebecca Kaye; Sophie Riedl; Hrvoje Bogunovic; Ursula Schmidt-Erfurth; Hendrik P Scholl; Daniel Rueckert; Andrew J Lotery; Sobha Sivaprasad; Martin Joseph Menten

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):1283.

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Investigating the role of GNGT2-mediated GPCR signalling in cone development

Specializing vision-language models for the clinical management of age-related macular degeneration

Early life pre-disposition to diet-induced retinal pathology

Functional outcomes across high-risk OCT-based phenotypes in intermediate age-related macular degeneration in the prospective PINNACLE study

Prototypical Machine Learning for Individual Prediction of Conversion to Atrophic AMD in the PINNACLE Study

Pointwise structure-function correlation between focal event-targeted microperimetry and the first sign of conversion to advanced AMD in the PINNACLE study

Studies in the 5xFAD mouse retina reveal chronic Amyloid-beta mediated effects, providing new insights into complex retinopathies

Pointwise correlation of deep learning-based quantified features of intermediate AMD on OCT and standardized retinal sensitivity in the prospective PINNACLE study

Targeted Microperimetry Grids for Focal Lesions in Intermediate AMD: PINNACLE Study Report 7

Using adaptive optics to assess hyporeflective clumps as a biomarker for progression to cRORA in the PINNACLE study

A clinical study evaluating biomarkers of immunosenescence in the progression of Age-Related Macular Degeneration (The Immuno AMD Study)

OCT-based AI-assisted phenotyping of intermediate AMD in the prospective PINNACLE trial

Molecular and Cellular Mechanisms of Levodopa-Mediated Visual Function Rescue in Albinism

Remofuscin slows retinal thinning in Stargardt Disease (STGD1) – results from the Stargardt Remofuscin Treatment Trial (STARTT) a 2-year placebo-controlled study.

Real world treatment intervals in eyes with nAMD treated with Aflibercept. Retrospective UK multicentre study.

Evaluating the distribution of fundus autofluorescence phenotypes in a large, European intermediate AMD cohort and describing a novel phenotype (A PINNACLE Study Report)

Patient-tailored Microperimetry Grids for Focal Lesions in Intermediate AMD: A PINNACLE Study Report

Inequalities in Uptake and Use of Digital Applications for Home-Monitoring of Neovascular Age-Related Macular Degeneration in an Elderly Visually Impaired Population: The MONARCH Study

Comparison of Novel Volumetric Microperimetry Metrics in Intermediate Age-Related Macular Degeneration: PINNACLE Study Report 3

Deep-learning-based clustering of OCT images for automated biomarker discovery in age-related macular degeneration

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