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Genetics November 2022

Zfp503/Nlz2 Is Required for RPE Differentiation and Optic Fissure Closure

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Elangovan Boobalan; Amy H. Thompson; Ramakrishna P. Alur; David M. McGaughey; Lijin Dong; Grace Shih; Emile R. Vieta-Ferrer; Ighovie F. Onojafe; Vijay K. Kalaskar; Gavin Arno; Andrew J. Lotery; Bin Guan; Chelsea Bender; Omar Memon; Lauren Brinster; Clement Soleilhavoup; Lia Panman; Tudor C. Badea; Andrea Minella; Antonio Jacobo Lopez; Sara M. Thomasy; Ala Moshiri; Delphine Blain; Robert B. Hufnagel; Tiziana Cogliati; Kapil Bharti; Brian P. Brooks
TAGS: embryo, fissure, mice, optics, eye, transcription factor
Invest. Ophthalmol. Vis. Sci.. 2022; 63(12):5. doi: https://doi.org/10.1167/iovs.63.12.5

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2022

UK Biobank retinal imaging grading: methods, baseline characteristics and findings for common ocular diseases.

Katie Curran; Alasdair Warwick; Barbra Hamill; Anthony Khawaja; Paul Foster; Andrew J Lotery; Konstantinos Balaskas; Savita Madhusudhan; Michael Joseph Quinn; Alyson Muldrew; catherine Jamison; Peter Blows; David Parry; Nisha Shah; Irene Leung; Tunde Peto

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):993 – F0240. doi:

ARVO Annual Meeting Abstract June 2022

Characterising individuals with retinopathy from retinal image grading data in UK Biobank

Alasdair Warwick; Barbra Hamill; Katie Curran; Anthony Khawaja; Andrew J Lotery; Paul Foster; Konstantinos Balaskas; Michael Joseph Quinn; Savita Madhusudhan; Alan Sproule; Sophie Leach; Daniela Florea; Muldrew Alyson; Laura Cushley; Graham Young; Tunde Peto

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):814. doi:

ARVO Annual Meeting Abstract June 2022

Impact of COVID-19 pandemic on patients with nAMD: Assessing clinical outcomes of patients who underwent four and eight weekly anti-VEGF treatment with no clinic review

Abeir Baltmr; Mohamed Farag; Panos Vouzounis; Sameh Alkhalili; Eslam Ahmed; Mohamed Eldakkak; Samir Khandhadia; Ramez Borbara; Christina Rennie; Gabriella DeSalvo; Andrew J Lotery

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):1340 – F0174. doi:

ARVO Annual Meeting Abstract June 2022

The impact of COVID-19 on visual acuity for nAMD patients treated with aflibercept in the UK

Clare Bailey; Marta Helena Gruszka-Goh; Andrew J Lotery; Romi Chhabra; Haralabos Eleftheriadis; Faruque Ghanchi; Colin Jones; Peter H Scanlon

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):1336 – F0170. doi:

ARVO Annual Meeting Abstract June 2022

Adaptive optics phenotypes of intermediate age-related macular degeneration

Ahmed M Hagag; Sophie Riedl; Toby Prevost; Lars Fritsche; Daniel Rueckert; Hendrik P Scholl; Ursula Schmidt-Erfurth; Sobha Sivaprasad; Andrew J Lotery

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2322. doi:

ARVO Annual Meeting Abstract June 2022

Assessing choroidal thickness in eyes with idiopathic serous epithelial detachments in UK Biobank

catherine Jamison; Barbra Hamill; Michael Joseph Quinn; Alyson Muldrew; Alan Sproule; Graham Young; Peter Blows; Laura Cushley; Savita Madhusudhan; Konstantinos Balaskas; Andrew J Lotery; Tunde Peto; Paul Foster

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2542 – A0111. doi:

ARVO Annual Meeting Abstract June 2022

Risk factors for progression of intermediate age-related macular degeneration: A systematic review and meta-analysis

Andrew J Lotery; Ahmed M Hagag; Rebecca Kaye; Sophie Riedl; Vy Hoang; Philipp Anders; Christian Appenzeller-Herzog; Ursula Schmidt-Erfurth; Hendrik P Scholl; Toby Prevost; Lars Fritsche; Daniel Rueckert; Sobha Sivaprasad; Ghislaine Traber; Beth Stuart

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2530 – A0099. doi:

ARVO Annual Meeting Abstract June 2022

Assessing the impact of COVID-19 on visual acuity for diabetic macular edema patients treated with aflibercept in the UK

Peter H Scanlon; Charlotte Frances Elizabeth Norridge; Rajarshi Mukherjee; Andrew J Lotery; Tunde Peto; Romi Chhabra; Clare Bailey; Haralabos Eleftheriadis; Faruque Ghanchi; Colin Jones

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3776 – F0197. doi:

ARVO Annual Meeting Abstract June 2022

Reliability of Quantitative Autofluorescence Imaging in a Multicenter Study Involving Patients with Stargardt Disease

Jeroen Adrianus Antonius Hendrikus Pas; Patty P.A. Dhooge; Philipp T. Möller; Katarina Stingl; Camiel J F Boon; Andrew J Lotery; Maurizio Battaglia Parodi; Philipp Herrmann; Wolfgang Klein; Mario G Fsadni; Thomas H. Wheeler-Schilling; Frank G Holz; Carel C B Hoyng; Steffen Schmitz-Valckenberg

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):4098 – F0062. doi:

ARVO Annual Meeting Abstract June 2022

Investigation of intermediate AMD with MAIA microperimetry metrics by the PINNACLE Consortium

Philipp Anders; Ghislaine L Traber; Ahmed M Hagag; Sophie Riedl; Lars Fritsche; Daniel Rueckert; Ursula Schmidt-Erfurth; Sobha Sivaprasad; Andrew J Lotery; Hendrik P Scholl

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):876. doi:

ARVO Annual Meeting Abstract June 2022

Self-supervised pretraining enables deep learning-based classification of AMD with fewer annotations

Robbie Holland; Martin Joseph Menten; Oliver Leingang; Hrvoje Bogunovic; Ahmed M Hagag; Rebecca Kaye; Sophie Riedl; Ghislaine Traber; Lars Fritsche; Toby Prevost; Hendrik P Scholl; Ursula Schmidt-Erfurth; Sobha Sivaprasad; Daniel Rueckert; Andrew J Lotery

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3004 – F0274. doi:

ARVO Annual Meeting Abstract June 2022

Automated deep learning-based AMD stage detection in real-world OCT datasets

Oliver Leingang; Hrvoje Bogunovic; Sophie Riedl; Arunava Chakravarty; Martin Joseph Menten; Robbie Holland; Ghislaine L Traber; Lars Fritsche; Toby Prevost; Hendrik P Scholl; Daniel Rueckert; Sobha Sivaprasad; Andrew J Lotery; Ursula Schmidt-Erfurth

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2106 – F0095. doi:

ARVO Annual Meeting Abstract June 2022

Automated detection of morphologic changes on SD-OCT leading toward outer retinal atrophy in intermediate age-related macular degeneration in the prospective PINNACLE trial

Sophie Riedl; Wolf-Dieter Vogl; Oliver Leingang; Hrvoje Bogunovic; Lars Fritsche; Toby Prevost; Daniel Rueckert; Hendrik P Scholl; Sobha Sivaprasad; Andrew J Lotery; Ursula Schmidt-Erfurth

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2319. doi:

ARVO Annual Meeting Abstract June 2022

Impaired glutamylation of ORF15 presents a unique phenotype in RPGR-related retinal dystrophy

Jasmina Cehajic Kapetanovic; Cristina Martinez-Fernandez de la Camara; Johannes Birtel; Salwah Rehman; Michelle E. McClements; Peter Charbel Issa; Andrew J Lotery; Robert E MacLaren

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):137 – A0317. doi:

ARVO Annual Meeting Abstract June 2022

Discovery of imaging biomarkers for healthy aging and age-related macular degeneration using counterfactual generative adversarial networks

Martin Joseph Menten; Oliver Leingang; Hrvoje Bogunovic; Robbie Holland; Ahmed M Hagag; Rebecca Kaye; Sophie Riedl; Ghislaine Traber; Lars Fritsche; Toby Prevost; Hendrik P Scholl; Ursula Schmidt-Erfurth; Sobha Sivaprasad; Daniel Rueckert; Andrew J Lotery

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3855. doi:

ARVO Annual Meeting Abstract June 2021

Clinical and genetic spectrum of patients with GUCY2D -associated retinal dystrophies

Leo Hahn; Mary J. van Schooneveld; Michalis Georgiou; Magda Meester-Smoor; Andrew J Lotery; Maria M. van Genderen; Jeannette Ossewaarde-van Norel; L. Ingeborgh van den Born; Carel Hoyng; Caroline C. W. Klaver; Susan M Downes; Martin McKibbin; Arthur A.B. Bergen; Bart Leroy; Michel Michaelides; Camiel Boon

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1544. doi:

ARVO Annual Meeting Abstract June 2021

Choroidal Vascularity in Chronic Central Serous Chorioretinopathy

Rebecca Kaye; Tunde Peto; Andrew J Lotery

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1902. doi:

ARVO Annual Meeting Abstract June 2021

Visual function improvements with BIIB112 (NSR-RPGR) in X-linked retinitis pigmentosa: XIRIUS (dose-expansion) and XOLARIS (natural disease progression) studies

Robert E MacLaren; Byron L Lam; Andrew J Lotery; Paulo Eduardo Stanga; Assad Jalil; Mark E Pennesi; David G Birch; Christine Kay; Jiajun Liu; Eileen Liao; Lenore von Krusenstiern

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1479. doi:

Articles March 2021

Reliability of Retinal Pathology Quantification in Age-Related Macular Degeneration: Implications for Clinical Trials and Machine Learning Applications

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Philipp L. Müller; Bart Liefers; Tim Treis; Filipa Gomes Rodrigues; Abraham Olvera-Barrios; Bobby Paul; Narendra Dhingra; Andrew Lotery; Clare Bailey; Paul Taylor; Clarisa I. Sánchez; Adnan Tufail
TAGS: age-related macular degeneration, machine learning, pathology, reliability, drusen, diagnostic imaging
Trans. Vis. Sci. Tech.. 2021; 10(3):4. doi: https://doi.org/10.1167/tvst.10.3.4

Includes: Supplemental Content

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Zfp503/Nlz2 Is Required for RPE Differentiation and Optic Fissure Closure

UK Biobank retinal imaging grading: methods, baseline characteristics and findings for common ocular diseases.

Characterising individuals with retinopathy from retinal image grading data in UK Biobank

Impact of COVID-19 pandemic on patients with nAMD: Assessing clinical outcomes of patients who underwent four and eight weekly anti-VEGF treatment with no clinic review

The impact of COVID-19 on visual acuity for nAMD patients treated with aflibercept in the UK

Adaptive optics phenotypes of intermediate age-related macular degeneration

Assessing choroidal thickness in eyes with idiopathic serous epithelial detachments in UK Biobank

Risk factors for progression of intermediate age-related macular degeneration: A systematic review and meta-analysis

Assessing the impact of COVID-19 on visual acuity for diabetic macular edema patients treated with aflibercept in the UK

Reliability of Quantitative Autofluorescence Imaging in a Multicenter Study Involving Patients with Stargardt Disease

Investigation of intermediate AMD with MAIA microperimetry metrics by the PINNACLE Consortium

Self-supervised pretraining enables deep learning-based classification of AMD with fewer annotations

Automated deep learning-based AMD stage detection in real-world OCT datasets

Automated detection of morphologic changes on SD-OCT leading toward outer retinal atrophy in intermediate age-related macular degeneration in the prospective PINNACLE trial

Impaired glutamylation of ORF15 presents a unique phenotype in RPGR-related retinal dystrophy

Discovery of imaging biomarkers for healthy aging and age-related macular degeneration using counterfactual generative adversarial networks

Clinical and genetic spectrum of patients with GUCY2D -associated retinal dystrophies

Choroidal Vascularity in Chronic Central Serous Chorioretinopathy

Visual function improvements with BIIB112 (NSR-RPGR) in X-linked retinitis pigmentosa: XIRIUS (dose-expansion) and XOLARIS (natural disease progression) studies

Reliability of Retinal Pathology Quantification in Age-Related Macular Degeneration: Implications for Clinical Trials and Machine Learning Applications

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