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ARVO Annual Meeting Abstract June 2022

Long-term safety and efficacy of sepofarsen in a Ph1b/2 INSIGHT extension trial in CEP290 -associated Leber congenital amaurosis (LCA10)

Stephen R Russell; Arlene V Drack; Artur V Cideciyan; Samuel G. Jacobson; Bart P Leroy; Caroline Van Cauwenbergh; Michael Schwartz; Aniz Girach

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):453. doi:

ARVO Annual Meeting Abstract June 2022

Efficacy and safety of sepofarsen, an intravitreal RNA antisense oligonucleotide, for the treatment of CEP290 -associated Leber congenital amaurosis (LCA10): a randomized, double-masked, sham-controlled, Phase 3 study (ILLUMINATE)

Bart Peter Leroy; Katarina Stingl; Isabelle S Audo; Camiel J F Boon; Fernanda Belga O Porto; Michel Michaelides; Helene Dollfus; L. Ingeborgh van den Born; Lyubomyr M Lytvynchuk; Francesca Simonelli; Juliana M F Sallum; Robert K Koenekoop; Elise Heon; Stephen R Russell; Michael Schwartz; Aniz Girach

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):4536 – F0323. doi:

ARVO Annual Meeting Abstract June 2021

Safety and efficacy of sepofarsen in the second treated eye in a Ph1b/2 extension trial in Leber Congenital Amaurosis type 10 (LCA10)

Stephen R Russell; Arlene V Drack; Artur V Cideciyan; Samuel G Jacobson; Bart Leroy; Allen Ho; Caroline Van Cauwenbergh; Arun kumar Krishnan; Wilhelmina R. den Hollender; Adriana Hollestein-Havelaar; Mike Schwartz; Aniz Girach

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):3317. doi:

ARVO Annual Meeting Abstract June 2020

Results of a phase 1b/2 trial of intravitreal (IVT) sepofarsen (QR-110) antisense oligonucleotide in Leber congenital amaurosis 10 (LCA10) due to p.Cys998X mutation in the CEP290 gene

Stephen R Russell; Arlene V Drack; Artur V Cideciyan; Samuel G Jacobson; Bart Peter Leroy; Wanda L. Pfeifer; Alina V. Dumitrescu; Alexandra V. Garafolo; Allen C. Ho; Caroline Van Cauwenbergh; Julie De Zaeytijd; Aniz Girach; Wil den Hollander; Mike Schwartz; David M. Rodman

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):866. doi:

ARVO Annual Meeting Abstract July 2018

Relationship between Choroidal Structural Parameters and Photoreceptor Layer Area in Choroideremia

Swetha Bindu Velaga; Amir H Hariri; Muneeswar Gupta Nittala; Aniz Girach; Kiran Vupparaboina; Jay Chhablani; Srinivas R. Sadda

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1513. doi:

ARVO Annual Meeting Abstract July 2018

The impact of scanning density on quantitative analyses in optical coherence tomography for choroideremia

Amy McIntosh; Swetha Velaga; Muneeswar Gupta Nittala; Amir H Hariri; Aniz Girach; Srinivas R. Sadda; Michael S Ip

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1680. doi:

ARVO Annual Meeting Abstract July 2018

Natural History of Progression of Choroideremia (NIGHT) Study: Cross-Sectional Analysis of Baseline Characteristics

Byron L Lam; M Dominik Fischer; Mark E Pennesi; Eeva-Marja Kaarina Sankila; Frank G. Holz; Robert E MacLaren; David G Birch; Ian M MacDonald; Carel C B Hoyng; Graeme Black; Neil M Bressler; Stephen H. Tsang; Kimberly E Stepien; Michael S Ip; Vedran Pavlovic; Aniz Girach

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3899. doi:

ARVO Annual Meeting Abstract July 2018

The Natural History of the Progression of Choroideremia (NIGHT) Study: Longitudinal Changes in Visual Acuity over 12 Months

Mark E Pennesi; Byron L Lam; M Dominik Fischer; Eeva-Marja Kaarina Sankila; Frank G. Holz; Robert E MacLaren; David G Birch; Ian M MacDonald; Graeme Black; Carel C B Hoyng; Neil M Bressler; Stephen H. Tsang; Kimberly E Stepien; Michael S Ip; Vedran Pavlovic; Aniz Girach

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3898. doi:

ARVO Annual Meeting Abstract July 2018

Spatial distribution of preserved autofluorescence in patients with choroideremia

Amir H Hariri; Aniz Girach; Michael S Ip; Byron L Lam; M Dominik Fischer; Eeva-Marja Kaarina Sankila; Mark E Pennesi; Frank G. Holz; David G Birch; Robert E MacLaren; Ian M MacDonald; Carel C B Hoyng; Graeme Black; Neil M Bressler; Stephen H. Tsang; Srinivas R. Sadda

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):4991. doi:

ARVO Annual Meeting Abstract June 2017

Measurement and Reproducibility of Preserved Ellipsoid Zone Area and Preserved Autofluorescence Area in a Natural History Study of a Cohort of Eyes with Choroideremia

Amir H Hariri; Swetha Bindu Velaga; Aniz Girach; Michael S Ip; Philip Le; Srinivas R Sadda

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):4748. doi:

Retina October 2013

Vitreous Levels of Active Ocriplasmin Following Intravitreal Injection: Results of an Ascending Exposure Trial

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Peter Stalmans; Aniz Girach
TAGS: ocriplasmin, vitreous body, intravitreal injections
Invest. Ophthalmol. Vis. Sci.. 2013; 54(10):6620-6627. doi: https://doi.org/10.1167/iovs.13-11811

Multidisciplinary Ophthalmic Imaging October 2012

Assessment of Retinal Morphology with Spectral and Time Domain OCT in the Phase III Trials of Enzymatic Vitreolysis

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Francisco A. Folgar; Cynthia A. Toth; Francis Char DeCroos; Aniz Girach; Steve Pakola; Glenn J. Jaffe
TAGS: eye, language morphology, morphology, ocriplasmin, phase 3 clinical trials, diagnostic imaging, macular holes, vitreomacular traction syndrome, surrogate endpoints
Invest. Ophthalmol. Vis. Sci.. 2012; 53(11):7395-7401. doi: https://doi.org/10.1167/iovs.12-10379

Letters to the Editor December 2010

Author Response: Effect of Ruboxistaurin on the Visual Acuity Decline Associated with Long-standing Diabetic Macular Edema

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Matthew J. Sheetz; Matthew D. Davis; Lloyd P. Aiello; Roy C. Milton; Ronald P. Danis; Xin Zhi; Aniz Girach; Maria C. Jimenez; Louis Vignati; for the PKC-DRS2 Study Group
TAGS: diabetic macular edema, visual acuity
Invest. Ophthalmol. Vis. Sci.. 2010; 51(12):6890-6891. doi: https://doi.org/10.1167/iovs.09-4285

Clinical Trials January 2009

Effect of Ruboxistaurin on the Visual Acuity Decline Associated with Long-standing Diabetic Macular Edema

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Matthew D. Davis; Matthew J. Sheetz; Lloyd P. Aiello; Roy C. Milton; Ronald P. Danis; Xin Zhi; Aniz Girach; Maria C. Jimenez; Louis Vignati
TAGS: diabetic macular edema, eye, placebos, visual acuity
Invest. Ophthalmol. Vis. Sci.. 2009; 50(1):1-4. doi: https://doi.org/10.1167/iovs.08-2473

Clinical and Epidemiologic Research September 2007

Progression of Diabetic Macular Edema: Correlation with Blood–Retinal Barrier Permeability, Retinal Thickness, and Retinal Vessel Diameter

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Birgit Sander; Dorte Nellemann Thornit; Lotte Colmorn; Charlotte Strøm; Aniz Girach; Larry D. Hubbard; Henrik Lund-Andersen; Michael Larsen
TAGS: blood-retinal barrier, diabetic macular edema, diameter, eye, light coagulation, permeability, retinal vessels, edema, retinal diseases
Invest. Ophthalmol. Vis. Sci.. 2007; 48(9):3983-3987. doi: https://doi.org/10.1167/iovs.06-1102

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Long-term safety and efficacy of sepofarsen in a Ph1b/2 INSIGHT extension trial in CEP290 -associated Leber congenital amaurosis (LCA10)

Efficacy and safety of sepofarsen, an intravitreal RNA antisense oligonucleotide, for the treatment of CEP290 -associated Leber congenital amaurosis (LCA10): a randomized, double-masked, sham-controlled, Phase 3 study (ILLUMINATE)

Safety and efficacy of sepofarsen in the second treated eye in a Ph1b/2 extension trial in Leber Congenital Amaurosis type 10 (LCA10)

Results of a phase 1b/2 trial of intravitreal (IVT) sepofarsen (QR-110) antisense oligonucleotide in Leber congenital amaurosis 10 (LCA10) due to p.Cys998X mutation in the CEP290 gene

Relationship between Choroidal Structural Parameters and Photoreceptor Layer Area in Choroideremia

The impact of scanning density on quantitative analyses in optical coherence tomography for choroideremia

Natural History of Progression of Choroideremia (NIGHT) Study: Cross-Sectional Analysis of Baseline Characteristics

The Natural History of the Progression of Choroideremia (NIGHT) Study: Longitudinal Changes in Visual Acuity over 12 Months

Spatial distribution of preserved autofluorescence in patients with choroideremia

Measurement and Reproducibility of Preserved Ellipsoid Zone Area and Preserved Autofluorescence Area in a Natural History Study of a Cohort of Eyes with Choroideremia

Vitreous Levels of Active Ocriplasmin Following Intravitreal Injection: Results of an Ascending Exposure Trial

Assessment of Retinal Morphology with Spectral and Time Domain OCT in the Phase III Trials of Enzymatic Vitreolysis

Author Response: Effect of Ruboxistaurin on the Visual Acuity Decline Associated with Long-standing Diabetic Macular Edema

Effect of Ruboxistaurin on the Visual Acuity Decline Associated with Long-standing Diabetic Macular Edema

Progression of Diabetic Macular Edema: Correlation with Blood–Retinal Barrier Permeability, Retinal Thickness, and Retinal Vessel Diameter

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